tetracycline and Acidosis

Topics: Acidosis; Adult; Fanconi Syndrome; Female; Humans; Lactates; Tetracycline

Topics: Acidosis; Biguanides; Diabetes Mellitus; Drug Interactions; Humans; Phenformin; Tetracycline

Tetracycline generally is believed to be a safe drug with relatively minor side effects. Serious irreversible renal damage and metabolic acidosis can occur in patients with azotemia. While the exact mechanism is unknown, the commonly reported nephrotoxic and metabolic effects of tetracycline are reviewed and an illustrative case is presented.

Topics: Acidosis; Acute Kidney Injury; Aged; Female; Humans; Infusions, Parenteral; Pregnancy; Tetracycline

Topics: Acidosis; Animals; Ascorbic Acid; Bicarbonates; Calcium; Carbon Dioxide; Dogs; Hydrochloric Acid; Hydrogen-Ion Concentration; Injections, Intravenous; Lactates; Oxygen; Pyruvates; Tetracycline

Topics: Acidosis; Administration, Oral; Adolescent; Adult; Aged; Bangladesh; Bicarbonates; Child; Child, Preschool; Cholera; Dehydration; Diarrhea; Female; Glucose; Humans; Infant; Injections, Intravenous; Male; Middle Aged; Refugees; Sodium Chloride; Solutions; Tetracycline; Vomiting; Water-Electrolyte Balance

Topics: Acidosis; Clostridium Infections; Clostridium perfringens; Endocarditis, Bacterial; Enterococcus faecalis; Heart Failure; Humans; Male; Middle Aged; Penicillin Resistance; Penicillins; Streptococcal Infections; Streptomycin; Tetracycline

Topics: Acidosis; Acute Kidney Injury; Animals; Bone Diseases; Bone Regeneration; Bone Resorption; Chronic Kidney Disease-Mineral and Bone Disorder; Hyperplasia; Male; Nephrectomy; Osteoclasts; Osteomalacia; Parathyroid Glands; Rats; Tetracycline; Tibia; Time Factors; Uremia

Topics: Acidosis; Animals; Blood Urea Nitrogen; Colon, Sigmoid; Dogs; Electrolytes; Humans; Kidney; Methods; Postoperative Complications; Surgical Wound Infection; Tetracycline; Ureter; Urinary Diversion; Urography; Vesico-Ureteral Reflux

Topics: Acidosis; Adult; Female; Humans; Lactates; Phenformin; Pulmonary Edema; Pyelonephritis; Tetracycline

Topics: Acidosis; Cystitis; Diabetes Complications; Escherichia coli Infections; Gases; Tetracycline; Urography

Topics: Acidosis; Acidosis, Renal Tubular; Ataxia; Biopsy; Blood; Chemistry, Pharmaceutical; Glycosuria; Glycosuria, Renal; Humans; Hypokalemia; Kidney Diseases; Neurologic Manifestations; Nystagmus, Pathologic; Pathology; Proteinuria; Renal Aminoacidurias; Tetracycline; Toxicology; Uric Acid; Urine

Topics: Acidosis; Acidosis, Renal Tubular; Anti-Bacterial Agents; Blood; Kidney Diseases; Kidney Tubules; Metabolism; Tetracycline; Toxicology; Urine

Boric acid poisoning in 11 infants, occurring in the newborn nursery as a result of the accidental and inadvertent use of 2.5% boric acid in the preparation of the formulae, is reported. Five of the infants died. All except two exhibited the classical symptomatology of acute boric acid poisoning, namely, diarrhea, vomiting, erythema, exfoliation, desquamation of the skin, and marked central nervous system irritation. Early manifestations of poisoning were nonspecific, and one patient died before skin manifestations were noted. Peritoneal dialysis, instituted in nine cases, was found to be the most effective method of treatment. It is recommended that boric acid, which is of doubtful therapeutic value, should be completely removed from hospitals, dispensaries and pharmacopoeias.

Topics: Acidosis; Anti-Bacterial Agents; Borates; Boric Acids; Color Perception Tests; Dehydration; Diarrhea; Diarrhea, Infantile; Erythema; Exchange Transfusion, Whole Blood; Gastric Lavage; Hypernatremia; Infant; Infant, Newborn; Peritoneal Dialysis; Phenobarbital; Seizures; Tetracycline; Toxicology; Vomiting

Topics: Acidosis; Cesarean Section; Fatty Liver; Female; Hematemesis; Humans; Hypoproteinemia; Hypotension; Hysterectomy; Jaundice; Liver Diseases; Melena; Oxytetracycline; Pathology; Placenta Previa; Pneumonia; Postpartum Hemorrhage; Postpartum Period; Pregnancy; Pregnancy Complications; Tetracycline; Toxicology

Topics: Acidosis; Anti-Bacterial Agents; Endotoxins; Humans; Shock; Tetracycline

Topics: Acidosis; Amino Acids; Glycosuria; Proteinuria; Syndrome; Tetracycline