tetracycline and Vaginal-Diseases

Topics: Antifungal Agents; Candidiasis, Vulvovaginal; Female; Glucocorticoids; Gonorrhea; Haemophilus Infections; Herpes Simplex; Humans; Infant, Newborn; Infant, Newborn, Diseases; Metronidazole; Mycoplasma Infections; Ophthalmia Neonatorum; Penicillin G Procaine; Pregnancy; Pregnancy Complications, Infectious; Pregnancy in Diabetics; Syphilis; Syphilis Serodiagnosis; Syphilis, Congenital; Tetracycline; Trichomonas Vaginitis; Vaginal Diseases

A tetracycline and amphotericin B vaginal cream (Vagmycin; Squibb) was highly effective in mixed vaginal infections. More than 95% of patients had symptomatic relief while 85% showed bacterial and clinical response. There appeared to be little difference whether the cream was applied for 1 week or 2 weeks. A group of asymptomatic patients were evaluated to compare alterations in normal and pathological organisms as a result of treatment.

Topics: Amphotericin B; Drug Combinations; Female; Humans; Tetracycline; Time Factors; Vagina; Vaginal Creams, Foams, and Jellies; Vaginal Diseases

A proctocol to be administered by nurses for the management of dysuria, frequent urination, and vaginal discharge was validated. In a randomized, controlled trial, 146 women were seen by both nurse and physician and then assigned to either the nurse-proctocol treatment plan or the physician treatment plan. The clinical data collected by the nurse showed no important differences from the physicians' data. The protocol recommended that 89 percent of the patients be sent home without seeing the physician. The physicians agreed with the protocol-recommended disposition in all but two cases. All patients with complications were appropriately referred to the physician. In follow-up, more than 95 percent of both groups reported symptomatic improvement, and repeat urine cultures were negative. We conclude that the protocol can be accurately administered, makes sound recommendations, is safe, and efficiently saves physician time.

Topics: Adolescent; Adult; Ampicillin; Candidiasis, Vulvovaginal; Female; Humans; Nurses; Physicians; Sulfisoxazole; Syndrome; Tetracycline; Trichomonas Infections; Urethral Diseases; Urethritis; Urinary Tract Infections; Urination Disorders; Vagina; Vaginal Diseases; Vaginitis

To assess the usefulness of aspiration sclerotherapy in the treatment of hydroceles in the tropics.. This prospective study included 82 patients with 94 primary vaginal hydroceles of which 62 hydroceles were treated by aspiration and tetracycline hydrochloride sclerotherapy as an outpatient procedure (mean age of patients 56.5 years, range 40-82) and 28 were treated surgically and included as controls (mean age 52.4 years, range 40-70). All patients were followed for a year.. In the sclerotherapy group, the overall cure rate after a year was 95%. Few complications were encountered in this group: six patients (10%) experienced pain during the procedure, seven patients (12%) had local infection and three patients (5%) developed haematoma. No recurrence was encountered in the surgical group, seven patients (25%) had infection and two patients (7%) developed haematoma. The mean hospital stay for the surgical group was 3.4 +/- 1.3 days (range 1-7). Four patients with thick-walled hydroceles had persistent swelling after sclerotherapy, the recurrence of which dissatisfied the patients.. Aspiration sclerotherapy for thin-walled hydroceles proved to be a curative, simple, safe and cost-effective out-patient procedure. It can be an alternative to surgery in developing countries where resources are limited.

Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Female; Humans; Length of Stay; Male; Middle Aged; Prospective Studies; Recurrence; Sclerosing Solutions; Sclerotherapy; Testicular Hydrocele; Tetracycline; Tropical Medicine; Vaginal Diseases

Fifteen patients suffering from symptomatic Gartner cysts were subjected to cyst fluid aspiration and 5% tetracycline injection of a similar volume (as that of aspirated cyst fluid) under local analgesia. Twenty-four hours later the injected tetracycline was re-aspirated until the cyst walls collapsed. The procedure was easy, inexpensive, acceptable by all patients with no operative or postoperative complaints or complications and no cyst reformation. This novel technique is an ideal, safe and effective simple office procedure for management of symptomatic Gartner cysts.

Topics: Cysts; Female; Humans; Sclerotherapy; Suction; Tetracycline; Vaginal Diseases; Vulvar Diseases; Wolffian Ducts

The in vitro antibacterial activity of the antifungal compound fenticonazole was compared with those of clotrimazole, miconazole, tetracycline, and metronidazole against 177 strains of bacterial species associated with either bacterial vaginosis (BV) or skin infections by agar dilution MIC determinations. BV-associated Bacteroides isolates of the Bacteroides melaninogenicus-B. oralis group, Gardnerella vaginalis, Mobiluncus spp., and anaerobic, gram-positive cocci were highly susceptible to fenticonazole, clotrimazole, and miconazole; but Bacteroides spp. not associated with BV, Bacteroides ureolyticus and the Bacteroides fragilis group, were resistant. All Bacteroides strains were susceptible to metronidazole, but the susceptibility of G. vaginalis and Mobiluncus spp. varied. Among the skin bacteria, Staphylococcus aureus, coryneforms, and streptococci were highly susceptible to the imidazoles; but Staphylococcus epidermidis strains were generally resistant. This antibacterial activity may give fenticonazole a useful role in the topical treatment of vaginal discharge and in mycotic skin infections that are superinfected with bacteria.

Topics: Antifungal Agents; Bacteria; Female; Humans; Imidazoles; Metronidazole; Microbial Sensitivity Tests; Skin Diseases, Infectious; Tetracycline; Vaginal Diseases

Twenty nine patients with genital fixed drug eruptions were studied during one year. In 15 the genitalia were exclusively affected, whereas the other 14 had cutaneous lesions in addition. It was striking that those whose lesions were exclusively genital reported for consultation much earlier. Drug history was the mainstay of diagnosis. Provocation tests with graded doses of the suspected drug(s) were undertaken in all cases. Tetracycline was the commonest causative drug, followed by oxyphenbutazone and acetylsalicylic acid.

Topics: Adolescent; Adult; Child; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Penile Diseases; Skin Tests; Skin Ulcer; Tetracycline; Vaginal Diseases; Vulvar Diseases

A positive microbiological evidence could be obtained 54 times from the smear of the exterior genitals of 80 women suffering from complaints that were caused by urethritis, criteria of the examinations being sterile catheter specimen, negative cystoscopical findings, and missing indications to anatomical changes in the urethral region. Cytological examinations of these cases with regard to the vaginal epithelium had the following results:Group I:6 times; group II: 37 times; group IIW:8 times; group IIId: once; group IVa:twice. The cytological tests were carried out according to the method of papanicolaou as modified by Soost. Furthermore, we could state the following degrees of purity: Degree I: 8 times; degree II:16 times; degree III: 30 times. The cytological examinations of the urethral epithelium demonstrated, in 52 cases, an increased appearance of "nude" completely exposed epithelial cell nuclei--a fact corresponding to a degenerative autolysis (according to Wied). In the 26 women with missing atypical germ flora within the region of the exterior genitals, exclusively groups I (according to Papanicolaou and Soost) and degrees of purity I were stated. These persons also demonstrated remarkably grave psychical disturbances, especially in the intimate regions. In the cases of positive microbiological evidence, the following measures have proved satisfactory: Vaginal hygienization combined with a directly aimed antibacterial therapy, and the prescription of preparations containing lactic acid. A transitory discontinuation of contraceptives is being discussed. Our examination results are emphasizing the necessity of an analysis of the germ flora in cases of complaints arising from urethritis. Also psychical disturbances must be taken into consideration in cases of missing urological and gynaecological criteria of evidence.

Topics: Candidiasis, Vulvovaginal; Cervix Uteri; Chronic Disease; Female; Humans; Male; Metronidazole; Mycoplasma Infections; Nystatin; Psychophysiologic Disorders; Tetracycline; Trichomonas Vaginitis; Urethra; Urethritis; Vagina; Vaginal Diseases

Topics: Aged; Amphotericin B; Biopsy; Doxycycline; Escherichia coli; Estrogens; Female; Humans; Malacoplakia; Microscopy, Electron; Tetracycline; Vagina; Vaginal Diseases

The prevalence of tetracycline-resistant beta-haemolytic streptococci in South-west Essex has been recorded over the past 10 years. It has fallen from a peak of 35% in 1965 to a level of 9.2% in 1972. Ear infections no longer provide the highest incidence of these organisms; vaginal, perineal, and skin infections now seem to be of greater relative importance but throat swabs still provide the greatest actual number of isolations. Erythromycin-resistant strains are still rare.

Topics: Drug Resistance, Microbial; Ear; Ear Diseases; England; Erythromycin; Female; Humans; Nose; Paranasal Sinuses; Perineum; Pharynx; Skin Diseases; Sputum; Streptococcal Infections; Streptococcus pyogenes; Tetracycline; Vaginal Diseases; Vulva; Wounds and Injuries

Topics: Bacterial Infections; Female; Humans; Neomycin; Oxytetracycline; Sulfonamides; Tetracycline; Vaginal Diseases