An organosulfur compound with the general formula R-N=C=S.
ChEBI ID: 52221
| Member | Definition | Role |
|---|---|---|
| 1-naphthylisothiocyanate | 1-naphthyl isothiocyanate | |
| 6-methylthiohexyl isothiocyanate | A isothiocyanate that is hexane in which two of the terminal methyl hydrogens at positions 1 and 6 have been replaced by isothiocyanato and methylsulfanyl groups. | 1-isothiocyanato-6-(methylsulfanyl)hexane |
| allyl isothiocyanate | An isothiocyanate with the formula CH2=CHCH2N=C=S. A colorless oil with boiling point 152degreeC, it is responsible for the pungent taste of mustard, horseradish, and wasabi. | allyl isothiocyanate |
| amoscanate | An isothiocyanate that is phenyl isothiocyanate in which the hydrogen at the para- position has been replaced by a 4-nitroanilinyl group. | amoscanate |
| benzyl isothiocyanate | benzyl isothiocyanate | |
| butyl isothiocyanate | An isothiocyanate having a butyl group attached to the nitrogen. | butyl isothiocyanate |
| eosine-5-isothiocyanate | The 2',4',5',7'-tetrabromo-5-isothiocyanato derivative of fluorescein; exhibits phosphorescence with an emission maximum at ~680 nm. | eosin 5-isothiocyanate |
| erucin | Erucin | |
| ethyl isothiocyanate | An isothiocyanate having an ethyl group attached to the nitrogen. | ethyl isothiocyanate |
| iberin | An isothiocyanate that is 1-isothiocyanatopropane in which a hydrogen at position 3 has been replaced by a methylsulfinyl group. A glucosinolate hydrolysis product found in many members of the Brassicaceae family, it is a quorum-sensing inhibitor (QSI) of the bacterial pathogen Pseudomonas aeruginosa. | iberin |
| methyl isothiocyanate | An isothiocyanate having a methyl group attached to the nitrogen. It is also the active nematicide of the pronematicide metam-sodium. | methyl isothiocyanate |
| phenethyl isothiocyanate | An isothiocyanate having a phenethyl group attached to the nitrogen. It is a naturally occurring compound found in some cruciferous vegetables (e.g. watercress) and is known to possess anticancer properties. | phenethyl isothiocyanate |
| phenylisothiocyanate | An isothiocyanate having a phenyl group attached to the nitrogen; used for amino acid sequencing in the Edman degradation. | phenyl isothiocyanate |
| sulforaphane | An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen. | sulforaphane |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 301 (8.33) | 18.7374 |
| 1990's | 295 (8.16) | 18.2507 |
| 2000's | 708 (19.59) | 29.6817 |
| 2010's | 1,727 (47.77) | 24.3611 |
| 2020's | 584 (16.15) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 87 (2.19%) | 5.53% |
| Reviews | 217 (5.46%) | 6.00% |
| Case Studies | 11 (0.28%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 3,662 (92.08%) | 84.16% |