A humectant that is used as a food additive to prevent foodstuffs from drying out.
ChEBI ID: 77969
| Member | Definition | Class |
|---|---|---|
| mannitol | The D-enantiomer of mannitol. | D-mannitol |
| sorbitol | The D-enantiomer of glucitol (also known as D-sorbitol). | D-glucitol |
| triacetin | A triglyceride obtained by acetylation of the three hydroxy groups of glycerol. It has fungistatic properties (based on release of acetic acid) and has been used in the topical treatment of minor dermatophyte infections. | triacetin |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 7,903 (43.51) | 18.7374 |
| 1990's | 3,061 (16.85) | 18.2507 |
| 2000's | 3,358 (18.49) | 29.6817 |
| 2010's | 3,067 (16.89) | 24.3611 |
| 2020's | 773 (4.26) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 1,054 (5.31%) | 5.53% |
| Reviews | 926 (4.66%) | 6.00% |
| Case Studies | 598 (3.01%) | 4.05% |
| Observational | 46 (0.23%) | 0.25% |
| Other | 17,231 (86.78%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| 67.9K protein | Vaccinia virus | Potency | 5.0119 | 1 | 1 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 50.7151 | 2 | 2 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 10.6822 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 0.0038 | 1 | 1 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 65.7908 | 2 | 2 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 77.5854 | 1 | 1 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 0.0398 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 23.7781 | 1 | 1 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 2.8184 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 36.8840 | 3 | 3 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 15.4803 | 1 | 1 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 9.7674 | 1 | 1 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
| geminin | Homo sapiens (human) | Potency | 0.8280 | 2 | 3 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 7.6959 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 16.7570 | 2 | 3 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 0.0398 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 0.0398 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 35.4813 | 1 | 2 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 0.4020 | 1 | 2 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 1.0591 | 1 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 4.3277 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 5.2164 | 1 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 24.0151 | 1 | 1 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 43.6412 | 2 | 2 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 17.5225 | 2 | 2 |