EC 2.7.11.13 (protein kinase C) inhibitor

An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of protein kinase C (EC 2.7.11.13).

ChEBI ID: 37700

Members (20)

Member	Definition	Class
1-(5-isoquinolinesulfonyl)-2-methylpiperazine		1-(5-isoquinolinesulfonyl)-2-methylpiperazine; 5-(2-methylpiperazine-1-sulfonyl)isoquinoline
1-(5-isoquinolinesulfonyl)-2-methylpiperazine	A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.	1-(5-isoquinolinesulfonyl)-2-methylpiperazine; 5-(2-methylpiperazine-1-sulfonyl)isoquinoline
1-(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride	A hydrochloride salt prepared from anileridine and two molar equivalents of hydrogen chloride.	1-(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride
bisindolylmaleimide iii		bisindolylmaleimide III
chelerythrine	A benzophenanthridine alkaloid isolated from the root of Zanthoxylum simulans, Chelidonium majus L., and other Papaveraceae.	chelerythrine
d-alpha tocopherol	An alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils.	(R,R,R)-alpha-tocopherol
forapin	A 26-membered polypeptide consisting of Gly, Ile, Gly, Ala, Val, Leu, Lys, Val, Leu, Thr, Thr, Gly, Leu, Pro, Ala, Leu, Ile, Ser, Trp, Ile, Lys, Arg, Lys, Arg, Gln and Gln-NH2 residues joined in sequence. It is the principal active component of bee venom.	melittin
go 6976		Goe 6976
hispidin	Fungal metabolite first found in basidiomycete Inonotus hispidus (formerly Polyporus hispidus).	hispidin
mephentermine	A 2-aminooctadecane-1,3-diol having (2S,3R)-configuration.	sphinganine
midostaurin	An organic heterooctacyclic compound that is the N-benzoyl derivative of staurosporine.	midostaurin
myricitrin	A glycosyloxyflavone that consists of myricetin attached to a alpha-L-rhamnopyranosyl residue at position 3 via a glycosidic linkage. Isolated from Myrica cerifera, it exhibits anti-allergic activity.	myricitrin
norathyriol	A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3, 6 and 7. Isolated from Garcinia mangostana and Maclura pomifera, it exhibits inhibitory activity against protein kinase C.	norathyriol
ro 31-8220		Ro 31-8220
sf 2370	A organic heterooctacyclic compound that is a potent inhibitor of protein kinase C and is isolated from Nocardiopsis sp K-252a	K-252a
sotrastaurin	A member of the class of maleimides that is maleimide which is substituted at position 3 by an indol-3-yl group and at position 4 by a quinazolin-4-yl group, which in turn is substituted at position 2 by a 4-methylpiperazin-1-yl group. It is a potent and selective inhibitor of protein kinase C and has been investigated as an immunosuppresant in renal transplant patients.	sotrastaurin
staurosporine		staurosporine
suramin	A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.	suramin
suramin sodium	An organic sodium salt that is the hexasodium salt of suramin. It is an FDA approved drug for African sleeping sickness and river blindness.	suramin sodium
tamoxifen		tamoxifen

Research

Studies (58,960)

Timeframe	Studies, Drugs with This Role(%)	All Drugs %
pre-1990	10,839 (18.38)	18.7374
1990's	14,154 (24.01)	18.2507
2000's	16,686 (28.30)	29.6817
2010's	13,915 (23.60)	24.3611
2020's	3,366 (5.71)	2.80

Study Types

Publication Type	Studies, Drugs with this Role (%)	All Drugs (%)
Trials	5,314 (8.45%)	5.53%
Reviews	5,917 (9.41%)	6.00%
Case Studies	1,807 (2.87%)	4.05%
Observational	108 (0.17%)	0.25%
Other	49,707 (79.08%)	84.16%

Protein Targets (949)

Potency Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	Homo sapiens (human)	Potency	13.9480	1	2
15-lipoxygenase, partial	Homo sapiens (human)	Potency	19.9526	1	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	Leishmania major strain Friedlin	Potency	15.1014	1	1
67.9K protein	Vaccinia virus	Potency	14.4391	2	7
acetylcholinesterase	Homo sapiens (human)	Potency	62.9594	2	4
acid sphingomyelinase	Homo sapiens (human)	Potency	89.1251	1	1
activating transcription factor 6	Homo sapiens (human)	Potency	41.4720	2	5
aldehyde dehydrogenase 1 family, member A1	Homo sapiens (human)	Potency	26.1836	1	6
Alpha-synuclein	Homo sapiens (human)	Potency	18.3564	1	1
apical membrane antigen 1, AMA1	Plasmodium falciparum 3D7	Potency	35.4813	1	1
AR protein	Homo sapiens (human)	Potency	26.9855	7	15
arylsulfatase A	Homo sapiens (human)	Potency	11.7272	1	3
ATAD5 protein, partial	Homo sapiens (human)	Potency	10.4835	3	4
Ataxin-2	Homo sapiens (human)	Potency	34.6064	2	5
ATP-dependent phosphofructokinase	Trypanosoma brucei brucei TREU927	Potency	15.4500	2	4
ATPase family AAA domain-containing protein 5	Homo sapiens (human)	Potency	61.3172	1	2
atrial natriuretic peptide receptor 1 precursor	Homo sapiens (human)	Potency	16.9441	1	1
atrial natriuretic peptide receptor 2 precursor	Homo sapiens (human)	Potency	14.6892	1	1
Bloom syndrome protein isoform 1	Homo sapiens (human)	Potency	3.3975	2	3
bromodomain adjacent to zinc finger domain 2B	Homo sapiens (human)	Potency	58.2417	1	3
caspase 7, apoptosis-related cysteine protease	Homo sapiens (human)	Potency	44.3016	1	2
caspase-1 isoform alpha precursor	Homo sapiens (human)	Potency	39.8107	1	1
caspase-3	Cricetulus griseus (Chinese hamster)	Potency	39.4839	1	2
caspase-3	Homo sapiens (human)	Potency	44.3016	1	2
Caspase-7	Cricetulus griseus (Chinese hamster)	Potency	39.4839	1	2
Cellular tumor antigen p53	Homo sapiens (human)	Potency	41.5652	2	7
cellular tumor antigen p53 isoform a	Homo sapiens (human)	Potency	22.3831	2	7
Chain A, 2-oxoglutarate Oxygenase	Homo sapiens (human)	Potency	13.6788	1	2
Chain A, ATP-DEPENDENT DNA HELICASE Q1	Homo sapiens (human)	Potency	22.7993	3	8
Chain A, Beta-lactamase	Escherichia coli K-12	Potency	5.0119	1	1
Chain A, Breast cancer type 1 susceptibility protein	Homo sapiens (human)	Potency	14.2191	1	2
Chain A, Cruzipain	Trypanosoma cruzi	Potency	25.2041	1	3
Chain A, Ferritin light chain	Equus caballus (horse)	Potency	29.8357	1	6
Chain A, HADH2 protein	Homo sapiens (human)	Potency	16.5341	2	5
Chain A, JmjC domain-containing histone demethylation protein 3A	Homo sapiens (human)	Potency	38.1456	1	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	Homo sapiens (human)	Potency	18.5190	3	14
Chain A, Putative fructose-1,6-bisphosphate aldolase	Giardia intestinalis	Potency	12.2586	1	5
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	Homo sapiens (human)	Potency	12.5787	2	13
Chain B, HADH2 protein	Homo sapiens (human)	Potency	16.5341	2	5
chromobox protein homolog 1	Homo sapiens (human)	Potency	36.8884	2	5
cytochrome P450 2C19 precursor	Homo sapiens (human)	Potency	10.0000	1	1
cytochrome P450 2C9 precursor	Homo sapiens (human)	Potency	39.8107	1	1
cytochrome P450 2D6 isoform 1	Homo sapiens (human)	Potency	21.5617	1	3
cytochrome P450 3A4 isoform 1	Homo sapiens (human)	Potency	31.6228	2	6
cytochrome P450 family 3 subfamily A polypeptide 4	Homo sapiens (human)	Potency	37.9083	1	1
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	Homo sapiens (human)	Potency	6.0250	1	2
D(1A) dopamine receptor	Homo sapiens (human)	Potency	6.0200	2	2
D(1A) dopamine receptor	Sus scrofa (pig)	Potency	18.9850	1	2
Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)	Potency	25.1189	1	1
DNA polymerase beta	Homo sapiens (human)	Potency	3.7051	1	3
DNA polymerase eta isoform 1	Homo sapiens (human)	Potency	13.6096	1	3
DNA polymerase III, partial	Bacillus subtilis	Potency	25.9356	1	3
DNA polymerase iota isoform a (long)	Homo sapiens (human)	Potency	43.3114	2	5
DNA polymerase kappa isoform 1	Homo sapiens (human)	Potency	5.5372	1	5
dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)	Potency	0.1000	1	1
endonuclease IV	Escherichia coli	Potency	14.5704	2	3
epidermal growth factor receptor isoform a precursor	Homo sapiens (human)	Potency	0.1996	4	4
estrogen nuclear receptor alpha	Homo sapiens (human)	Potency	19.6172	10	21
estrogen receptor 2 (ER beta)	Homo sapiens (human)	Potency	54.2918	3	4
estrogen-related nuclear receptor alpha	Homo sapiens (human)	Potency	29.9130	9	17
euchromatic histone-lysine N-methyltransferase 2	Homo sapiens (human)	Potency	14.9433	1	13
EWS/FLI fusion protein	Homo sapiens (human)	Potency	5.2205	4	14
farnesoid X nuclear receptor	Homo sapiens (human)	Potency	49.5924	3	3
flap endonuclease 1	Homo sapiens (human)	Potency	8.5640	3	6
Fumarate hydratase	Homo sapiens (human)	Potency	24.0219	1	5
GABA theta subunit	Rattus norvegicus (Norway rat)	Potency	31.6228	1	3
galactokinase	Homo sapiens (human)	Potency	17.7828	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	Rattus norvegicus (Norway rat)	Potency	31.6228	1	3
Gamma-aminobutyric acid receptor subunit alpha-2	Rattus norvegicus (Norway rat)	Potency	31.6228	1	3
Gamma-aminobutyric acid receptor subunit alpha-3	Rattus norvegicus (Norway rat)	Potency	31.6228	1	3
Gamma-aminobutyric acid receptor subunit alpha-4	Rattus norvegicus (Norway rat)	Potency	31.6228	1	3
Gamma-aminobutyric acid receptor subunit alpha-5	Rattus norvegicus (Norway rat)	Potency	31.6228	1	3
Gamma-aminobutyric acid receptor subunit alpha-6	Rattus norvegicus (Norway rat)	Potency	31.6228	1	3
Gamma-aminobutyric acid receptor subunit beta-1	Rattus norvegicus (Norway rat)	Potency	31.6228	1	3
Gamma-aminobutyric acid receptor subunit beta-2	Rattus norvegicus (Norway rat)	Potency	31.6228	1	3
Gamma-aminobutyric acid receptor subunit beta-3	Rattus norvegicus (Norway rat)	Potency	31.6228	1	3
Gamma-aminobutyric acid receptor subunit delta	Rattus norvegicus (Norway rat)	Potency	31.6228	1	3
Gamma-aminobutyric acid receptor subunit epsilon	Rattus norvegicus (Norway rat)	Potency	31.6228	1	3
Gamma-aminobutyric acid receptor subunit gamma-1	Rattus norvegicus (Norway rat)	Potency	31.6228	1	3
Gamma-aminobutyric acid receptor subunit gamma-2	Rattus norvegicus (Norway rat)	Potency	31.6228	1	3
Gamma-aminobutyric acid receptor subunit gamma-3	Rattus norvegicus (Norway rat)	Potency	31.6228	1	3
Gamma-aminobutyric acid receptor subunit pi	Rattus norvegicus (Norway rat)	Potency	31.6228	1	3
geminin	Homo sapiens (human)	Potency	19.7172	3	4
GLI family zinc finger 3	Homo sapiens (human)	Potency	20.8408	2	4
GLS protein	Homo sapiens (human)	Potency	8.6342	2	5
glucocerebrosidase	Homo sapiens (human)	Potency	26.2617	1	6
glucocorticoid receptor [Homo sapiens]	Homo sapiens (human)	Potency	27.9814	3	6
glucokinase regulatory protein	Homo sapiens (human)	Potency	12.5893	1	1
Glutamate receptor 1	Rattus norvegicus (Norway rat)	Potency	8.9125	1	1
Glutamate receptor 2	Rattus norvegicus (Norway rat)	Potency	5.9243	2	3
Glutamate receptor 3	Rattus norvegicus (Norway rat)	Potency	8.9125	1	1
Glutamate receptor 4	Rattus norvegicus (Norway rat)	Potency	8.9125	1	1
GTP-binding nuclear protein Ran isoform 1	Homo sapiens (human)	Potency	1.4581	1	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	Homo sapiens (human)	Potency	11.7554	2	4
heat shock protein beta-1	Homo sapiens (human)	Potency	38.0938	2	3
hexokinase-4 isoform 1	Homo sapiens (human)	Potency	12.5893	1	1
Histamine H2 receptor	Cavia porcellus (domestic guinea pig)	Potency	14.2797	2	15
histone acetyltransferase KAT2A isoform 1	Homo sapiens (human)	Potency	29.9033	1	4
Histone H2A.x	Cricetulus griseus (Chinese hamster)	Potency	46.0876	2	4
histone-lysine N-methyltransferase 2A isoform 2 precursor	Homo sapiens (human)	Potency	11.0344	1	2
huntingtin isoform 2	Homo sapiens (human)	Potency	10.0000	1	1
hypothetical protein, conserved	Trypanosoma brucei	Potency	50.1187	1	1
hypoxia-inducible factor 1 alpha subunit	Homo sapiens (human)	Potency	45.9079	2	4
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	Homo sapiens (human)	Potency	22.1060	2	4
IDH1	Homo sapiens (human)	Potency	17.0255	1	3
importin subunit beta-1 isoform 1	Homo sapiens (human)	Potency	1.4581	1	1
Inositol monophosphatase 1	Rattus norvegicus (Norway rat)	Potency	5.7356	1	4
Integrin alpha-IIb	Homo sapiens (human)	Potency	20.2117	1	4
Integrin beta-3	Homo sapiens (human)	Potency	20.2117	1	4
Interferon beta	Homo sapiens (human)	Potency	12.6366	1	18
lamin isoform A-delta10	Homo sapiens (human)	Potency	8.3274	2	6
lethal factor (plasmid)	Bacillus anthracis str. A2012	Potency	23.1103	1	3
Luciferase	Photinus pyralis (common eastern firefly)	Potency	28.8984	3	3
lysosomal alpha-glucosidase preproprotein	Homo sapiens (human)	Potency	3.1623	1	1
M-phase phosphoprotein 8	Homo sapiens (human)	Potency	7.6435	1	5
Microtubule-associated protein tau	Homo sapiens (human)	Potency	16.1684	2	22
mitogen-activated protein kinase 1	Homo sapiens (human)	Potency	31.6228	1	1
muscarinic acetylcholine receptor M1	Rattus norvegicus (Norway rat)	Potency	18.5331	2	2
muscleblind-like protein 1 isoform 1	Homo sapiens (human)	Potency	11.9048	1	2
NFKB1 protein, partial	Homo sapiens (human)	Potency	5.7875	2	4
nonstructural protein 1	Influenza A virus (A/WSN/1933(H1N1))	Potency	6.3096	1	1
NPC intracellular cholesterol transporter 1 precursor	Homo sapiens (human)	Potency	58.0479	1	2
Nrf2	Homo sapiens (human)	Potency	16.3601	1	1
nuclear factor erythroid 2-related factor 2 isoform 1	Homo sapiens (human)	Potency	35.6184	2	3
nuclear factor erythroid 2-related factor 2 isoform 2	Homo sapiens (human)	Potency	23.1093	1	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	Homo sapiens (human)	Potency	27.5941	2	5
nuclear receptor ROR-gamma isoform 1	Mus musculus (house mouse)	Potency	14.5232	2	9
nuclear receptor subfamily 1, group I, member 3	Homo sapiens (human)	Potency	68.6943	3	4
Ornithine decarboxylase	Rattus norvegicus (Norway rat)	Potency	31.6228	1	1
Parkin	Homo sapiens (human)	Potency	16.6881	2	4
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Homo sapiens (human)	Potency	25.9031	2	2
peripheral myelin protein 22	Rattus norvegicus (Norway rat)	Potency	36.1254	1	1
peripheral myelin protein 22 isoform 1	Homo sapiens (human)	Potency	72.5206	1	2
peroxisome proliferator activated receptor gamma	Homo sapiens (human)	Potency	58.9321	3	4
peroxisome proliferator-activated receptor delta	Homo sapiens (human)	Potency	54.9410	2	2
phosphoglycerate kinase	Trypanosoma brucei brucei TREU927	Potency	1.6944	1	1
phosphopantetheinyl transferase	Bacillus subtilis	Potency	46.2919	2	15
plasminogen precursor	Mus musculus (house mouse)	Potency	8.9125	1	1
Platelet-activating factor receptor	Homo sapiens (human)	Potency	14.2191	1	2
polyprotein	Zika virus	Potency	24.0219	1	5
polyunsaturated fatty acid lipoxygenase ALOX12	Homo sapiens (human)	Potency	12.5893	1	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)	Potency	7.8970	1	6
potassium voltage-gated channel subfamily H member 2 isoform d	Homo sapiens (human)	Potency	3.5481	1	1
PPM1D protein	Homo sapiens (human)	Potency	12.6366	1	12
pregnane X nuclear receptor	Homo sapiens (human)	Potency	12.0214	1	2
progesterone receptor	Homo sapiens (human)	Potency	68.9104	3	4
pyruvate kinase	Leishmania mexicana mexicana	Potency	0.7943	2	2
pyruvate kinase PKM isoform b	Homo sapiens (human)	Potency	31.6228	2	2
RAF proto-oncogene serine/threonine-protein kinase isoform b	Homo sapiens (human)	Potency	0.1778	1	1
Rap guanine nucleotide exchange factor 3	Homo sapiens (human)	Potency	47.0685	2	2
RAR-related orphan receptor gamma	Mus musculus (house mouse)	Potency	29.3618	2	4
ras-related protein Rab-9A	Homo sapiens (human)	Potency	79.3696	1	3
regulator of G-protein signaling 4	Homo sapiens (human)	Potency	7.2505	1	8
retinoic acid nuclear receptor alpha variant 1	Homo sapiens (human)	Potency	48.4136	3	8
retinoid X nuclear receptor alpha	Homo sapiens (human)	Potency	38.6097	2	3
serine/threonine-protein kinase mTOR isoform 1	Homo sapiens (human)	Potency	15.8005	4	7
serine/threonine-protein kinase PLK1	Homo sapiens (human)	Potency	37.6858	1	1
Single-stranded DNA cytosine deaminase	Homo sapiens (human)	Potency	32.9838	1	6
SMAD family member 2	Homo sapiens (human)	Potency	59.3536	3	5
SMAD family member 3	Homo sapiens (human)	Potency	59.3536	3	5
Smad3	Homo sapiens (human)	Potency	0.7079	1	1
snurportin-1	Homo sapiens (human)	Potency	1.4581	1	1
survival motor neuron protein isoform d	Homo sapiens (human)	Potency	11.8012	1	6
TDP1 protein	Homo sapiens (human)	Potency	20.0614	2	20
thioredoxin reductase	Rattus norvegicus (Norway rat)	Potency	33.6045	2	8
Thrombopoietin	Homo sapiens (human)	Potency	2.9882	2	4
thyroid hormone receptor beta isoform 2	Rattus norvegicus (Norway rat)	Potency	12.1259	3	5
thyroid hormone receptor beta isoform a	Homo sapiens (human)	Potency	70.7946	1	1
thyroid stimulating hormone receptor	Homo sapiens (human)	Potency	39.9009	4	8
thyrotropin-releasing hormone receptor	Homo sapiens (human)	Potency	27.3185	2	4
transcriptional regulator ERG isoform 3	Homo sapiens (human)	Potency	11.2202	1	1
tumor susceptibility gene 101 protein	Homo sapiens (human)	Potency	50.1187	1	1
Type-1A angiotensin II receptor	Rattus norvegicus (Norway rat)	Potency	0.1000	1	1
Type-1B angiotensin II receptor	Rattus norvegicus (Norway rat)	Potency	0.1000	1	1
Type-2 angiotensin II receptor	Rattus norvegicus (Norway rat)	Potency	0.1000	1	1
tyrosine-protein kinase Yes	Homo sapiens (human)	Potency	0.1091	1	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	Homo sapiens (human)	Potency	25.1189	1	1
urokinase plasminogen activator surface receptor precursor	Mus musculus (house mouse)	Potency	8.9125	1	1
urokinase-type plasminogen activator precursor	Mus musculus (house mouse)	Potency	8.9125	1	1
USP1 protein, partial	Homo sapiens (human)	Potency	32.5754	1	5
v-jun sarcoma virus 17 oncogene homolog (avian)	Homo sapiens (human)	Potency	20.5188	2	4
vitamin D (1,25- dihydroxyvitamin D3) receptor	Homo sapiens (human)	Potency	61.6448	2	2
vitamin D3 receptor isoform VDRA	Homo sapiens (human)	Potency	53.4165	1	7
Voltage-dependent calcium channel gamma-2 subunit	Mus musculus (house mouse)	Potency	4.4302	1	2

Inhibition Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	Homo sapiens (human)	IC50	2.2337	3	3
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	Homo sapiens (human)	IC50	0.0120	1	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	Homo sapiens (human)	Ki	0.0050	1	1
3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)	IC50	2.4422	4	10
5-hydroxytryptamine receptor 1A	Rattus norvegicus (Norway rat)	IC50	12.1600	1	1
5-hydroxytryptamine receptor 1A	Rattus norvegicus (Norway rat)	Ki	6.9490	1	1
5-hydroxytryptamine receptor 1B	Rattus norvegicus (Norway rat)	IC50	12.1600	1	1
5-hydroxytryptamine receptor 1B	Rattus norvegicus (Norway rat)	Ki	6.9490	1	1
5-hydroxytryptamine receptor 2A	Homo sapiens (human)	IC50	4.8010	1	1
5-hydroxytryptamine receptor 2A	Rattus norvegicus (Norway rat)	IC50	4.0000	1	1
5-hydroxytryptamine receptor 2A	Homo sapiens (human)	Ki	1.3720	1	1
5-hydroxytryptamine receptor 2B	Homo sapiens (human)	IC50	2.0840	1	1
5-hydroxytryptamine receptor 2B	Homo sapiens (human)	Ki	1.3260	1	1
5-hydroxytryptamine receptor 2C	Homo sapiens (human)	IC50	0.4600	1	1
5-hydroxytryptamine receptor 2C	Homo sapiens (human)	Ki	0.2410	1	1
5-hydroxytryptamine receptor 4	Cavia porcellus (domestic guinea pig)	IC50	0.4600	1	1
5-hydroxytryptamine receptor 4	Cavia porcellus (domestic guinea pig)	Ki	0.2410	1	1
5-hydroxytryptamine receptor 6	Homo sapiens (human)	IC50	2.6790	1	1
5-hydroxytryptamine receptor 6	Homo sapiens (human)	Ki	1.1425	2	2
5'-AMP-activated protein kinase subunit beta-1	Homo sapiens (human)	IC50	3.0363	1	5
5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)	IC50	3.0363	1	5
7-dehydrocholesterol reductase	Homo sapiens (human)	IC50	0.0120	1	1
7,8-dihydro-8-oxoguanine triphosphatase	Homo sapiens (human)	IC50	100.0000	1	1
Acetylcholinesterase	Homo sapiens (human)	IC50	1.4500	1	1
Activated CDC42 kinase 1	Homo sapiens (human)	IC50	0.0298	2	2
Activin receptor type-1	Homo sapiens (human)	IC50	4.1977	2	6
Activin receptor type-1B	Homo sapiens (human)	IC50	9.1180	1	1
Acyl-CoA desaturase 1	Mus musculus (house mouse)	IC50	3.4000	1	1
Adenosine receptor A1	Homo sapiens (human)	IC50	23.7670	1	1
Adenosine receptor A1	Homo sapiens (human)	Ki	13.8640	1	1
Adenosine receptor A2a	Homo sapiens (human)	IC50	7.0990	1	1
Adenosine receptor A2a	Homo sapiens (human)	Ki	3.9850	1	1
Adenosine receptor A3	Homo sapiens (human)	IC50	3.7010	1	1
Adenosine receptor A3	Homo sapiens (human)	Ki	2.0920	1	1
Aldehyde oxidase	Homo sapiens (human)	IC50	0.0024	1	2
Aldo-keto reductase family 1 member B1	Rattus norvegicus (Norway rat)	IC50	1.4720	1	1
Aldo-keto reductase family 1 member B1	Rattus norvegicus (Norway rat)	Ki	1.4590	1	1
ALK tyrosine kinase receptor	Homo sapiens (human)	IC50	0.5597	18	18
Alpha-1A adrenergic receptor	Rattus norvegicus (Norway rat)	IC50	3.7010	1	1
Alpha-1A adrenergic receptor	Rattus norvegicus (Norway rat)	Ki	2.0920	1	1
Alpha-1B adrenergic receptor	Rattus norvegicus (Norway rat)	IC50	3.7010	1	1
Alpha-1B adrenergic receptor	Rattus norvegicus (Norway rat)	Ki	2.0920	1	1
Alpha-1D adrenergic receptor	Homo sapiens (human)	IC50	4.9820	1	1
Alpha-1D adrenergic receptor	Homo sapiens (human)	Ki	2.4490	1	1
Alpha-2A adrenergic receptor	Homo sapiens (human)	IC50	1.9350	1	1
Alpha-2A adrenergic receptor	Homo sapiens (human)	Ki	0.7260	1	1
Alpha-2B adrenergic receptor	Homo sapiens (human)	IC50	3.5180	1	1
Alpha-2B adrenergic receptor	Homo sapiens (human)	Ki	1.6060	1	1
Amine oxidase [flavin-containing] A	Homo sapiens (human)	IC50	12.7750	2	2
Amine oxidase [flavin-containing] A	Homo sapiens (human)	Ki	0.2200	1	1
Amine oxidase [flavin-containing] B	Homo sapiens (human)	IC50	20.0000	1	1
Amine oxidase [flavin-containing] B	Rattus norvegicus (Norway rat)	IC50	0.0025	1	5
Androgen receptor	Rattus norvegicus (Norway rat)	IC50	17.3423	2	2
Androgen receptor	Rattus norvegicus (Norway rat)	Ki	15.1080	1	1
Angiopoietin-1 receptor	Homo sapiens (human)	IC50	9,916.7352	6	6
Angiotensin-converting enzyme	Oryctolagus cuniculus (rabbit)	IC50	0.9670	1	1
Angiotensin-converting enzyme	Oryctolagus cuniculus (rabbit)	Ki	0.7922	1	1
Angiotensin-converting enzyme	Homo sapiens (human)	IC50	530.8000	1	1
Angiotensin-converting enzyme	Homo sapiens (human)	Ki	250.2000	1	1
AP2-associated protein kinase 1	Homo sapiens (human)	IC50	0.2000	1	1
Aromatic-L-amino-acid decarboxylase	Homo sapiens (human)	IC50	1,280.0000	1	1
Aspartyl/asparaginyl beta-hydroxylase	Homo sapiens (human)	IC50	8.7825	4	4
ATP-binding cassette sub-family C member 3	Homo sapiens (human)	IC50	133.0000	1	2
ATP-dependent 6-phosphofructokinase	Trypanosoma brucei brucei	IC50	3.0000	1	1
ATP-dependent translocase ABCB1	Homo sapiens (human)	IC50	19.7250	4	4
ATP-dependent translocase ABCB1	Homo sapiens (human)	Ki	0.1000	1	1
Aurora kinase A	Homo sapiens (human)	IC50	0.0114	24	24
Aurora kinase B	Homo sapiens (human)	IC50	0.3306	12	12
Aurora kinase C	Homo sapiens (human)	IC50	0.0022	2	2
B2 bradykinin receptor	Homo sapiens (human)	IC50	20.3560	1	1
B2 bradykinin receptor	Homo sapiens (human)	Ki	12.0480	1	1
Bcl-2-like protein 1	Homo sapiens (human)	IC50	100.0000	1	1
BDNF/NT-3 growth factors receptor	Homo sapiens (human)	IC50	0.0004	3	3
Beta-1 adrenergic receptor	Homo sapiens (human)	IC50	17.2890	1	1
Beta-1 adrenergic receptor	Homo sapiens (human)	Ki	9.9840	1	1
Beta-3 adrenergic receptor	Homo sapiens (human)	IC50	7.7030	1	1
Beta-3 adrenergic receptor	Homo sapiens (human)	Ki	5.7780	1	1
Beta-adrenergic receptor kinase 1	Homo sapiens (human)	IC50	1.1595	2	2
Beta-adrenergic receptor kinase 2	Homo sapiens (human)	IC50	0.8560	2	2
Bile salt export pump	Homo sapiens (human)	IC50	50.5857	5	7
Bone morphogenetic protein receptor type-1A	Homo sapiens (human)	IC50	4.2880	1	1
Bone morphogenetic protein receptor type-2	Homo sapiens (human)	IC50	1.9400	2	2
Breakpoint cluster region protein	Homo sapiens (human)	GI50	20.0000	1	1
Breakpoint cluster region protein	Homo sapiens (human)	IC50	0.0945	4	4
C-8 sterol isomerase	Saccharomyces cerevisiae S288C	Ki	1.5000	1	1
Calcium-dependent protein kinase 1	Plasmodium falciparum K1	IC50	0.2400	1	1
Calcium/calmodulin-dependent protein kinase kinase 1	Homo sapiens (human)	IC50	0.0359	2	2
Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)	IC50	0.0246	2	2
Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)	IC50	0.0032	2	2
Calcium/calmodulin-dependent protein kinase type 1B	Homo sapiens (human)	IC50	0.0044	2	2
Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)	IC50	0.0003	2	2
Calcium/calmodulin-dependent protein kinase type 1G	Homo sapiens (human)	IC50	0.0046	2	2
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)	IC50	0.0022	6	6
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Rattus norvegicus (Norway rat)	IC50	0.0590	1	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)	IC50	0.0018	7	7
Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)	IC50	0.1440	8	8
Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)	IC50	0.0026	5	5
Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)	IC50	0.1475	2	2
cAMP-dependent protein kinase	Oryctolagus cuniculus (rabbit)	IC50	0.0000	1	1
cAMP-dependent protein kinase catalytic subunit alpha	Bos taurus (cattle)	IC50	0.1281	7	19
cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)	IC50	0.2607	14	14
cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)	Ki	3.0000	1	1
cAMP-dependent protein kinase catalytic subunit alpha	Rattus norvegicus (Norway rat)	IC50	0.1662	4	4
cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)	IC50	0.2829	13	13
cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)	Ki	3.0000	1	1
cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)	IC50	0.3043	12	12
cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)	Ki	3.0000	1	1
cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)	IC50	0.0014	2	2
Canalicular multispecific organic anion transporter 1	Homo sapiens (human)	IC50	133.0000	1	2
Cannabinoid receptor 1	Rattus norvegicus (Norway rat)	IC50	0.0100	1	1
Casein kinase I isoform alpha	Homo sapiens (human)	IC50	3.4120	4	4
Casein kinase I isoform alpha-like	Homo sapiens (human)	IC50	1.8400	2	2
Casein kinase I isoform delta	Homo sapiens (human)	IC50	1.4000	1	1
Casein kinase I isoform epsilon	Homo sapiens (human)	IC50	1.4000	1	1
Casein kinase I isoform gamma-1	Homo sapiens (human)	IC50	5.3367	3	3
Casein kinase I isoform gamma-2	Homo sapiens (human)	IC50	1.9467	3	3
Casein kinase I isoform gamma-3	Homo sapiens (human)	IC50	2.6750	2	2
Casein kinase II subunit alpha	Homo sapiens (human)	IC50	27.6043	4	4
Casein kinase II subunit alpha	Mus musculus (house mouse)	IC50	10.0000	1	1
Casein kinase II subunit alpha'	Homo sapiens (human)	IC50	21.6172	5	5
Casein kinase II subunit alpha'	Mus musculus (house mouse)	IC50	10.0000	1	1
Casein kinase II subunit alpha'-interacting protein	Mus musculus (house mouse)	IC50	10.0000	1	1
Casein kinase II subunit beta	Homo sapiens (human)	IC50	35.6000	3	3
Casein kinase II subunit beta	Mus musculus (house mouse)	IC50	10.0000	1	1
Cathepsin B	Homo sapiens (human)	IC50	30.0000	1	1
CDK-activating kinase assembly factor MAT1	Homo sapiens (human)	IC50	0.1216	4	4
Cell division cycle 7-related protein kinase	Homo sapiens (human)	IC50	0.0548	2	2
cGMP-dependent protein kinase 1	Homo sapiens (human)	IC50	0.0027	5	5
cGMP-dependent protein kinase 2	Homo sapiens (human)	IC50	0.0161	2	2
Chain A, CES1 protein	Homo sapiens (human)	Ki	15.2000	1	1
Chain A, Glycogen Synthase Kinase-3 Beta	Homo sapiens (human)	IC50	0.0150	1	2
Chain A, Protein kinase C, theta type	Homo sapiens (human)	Ki	0.0003	1	1
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1	Homo sapiens (human)	IC50	0.0100	1	2
Chain A, Serine/threonine-protein kinase Chk1	Homo sapiens (human)	Ki	0.0078	1	3
Chain A, Serine/threonine-protein kinase pknB	Mycobacterium tuberculosis	IC50	1.0000	1	1
Chain A, Serine/threonine-protein kinase TAO2	Rattus norvegicus (Norway rat)	IC50	3.0000	1	1
Chain A, Tyrosine-protein kinase SYK	Homo sapiens (human)	IC50	0.0120	1	1
Chain A, Tyrosine-protein kinase ZAP-70	Homo sapiens (human)	IC50	0.0558	1	1
Chain B, Glycogen Synthase Kinase-3 Beta	Homo sapiens (human)	IC50	0.0150	1	1
Chain E, Camp-dependent Protein Kinase	Bos taurus (cattle)	Ki	0.0080	1	1
Chain X, Proto-oncogene tyrosine-protein kinase Fyn	Homo sapiens (human)	IC50	0.0048	1	1
Cholinesterase	Homo sapiens (human)	IC50	8.5800	1	1
Chymotrypsinogen B	Homo sapiens (human)	IC50	20.0000	1	1
Citron Rho-interacting kinase	Homo sapiens (human)	IC50	0.7490	2	2
Coiled-coil domain-containing protein 6	Homo sapiens (human)	IC50	0.0022	1	1
Cyclin-A1	Homo sapiens (human)	IC50	0.4610	5	5
Cyclin-A1	Homo sapiens (human)	Ki	0.0040	1	1
Cyclin-A2	Homo sapiens (human)	IC50	4.0307	13	13
Cyclin-A2	Homo sapiens (human)	Ki	0.0026	2	3
Cyclin-C	Homo sapiens (human)	IC50	0.0105	2	2
Cyclin-dependent kinase 1	Homo sapiens (human)	IC50	0.0075	23	23
Cyclin-dependent kinase 1	Homo sapiens (human)	Ki	0.0020	1	2
Cyclin-dependent kinase 1	Mus musculus (house mouse)	IC50	0.0080	1	1
Cyclin-dependent kinase 12	Homo sapiens (human)	IC50	0.0530	1	1
Cyclin-dependent kinase 13	Homo sapiens (human)	IC50	0.0570	1	1
Cyclin-dependent kinase 14	Homo sapiens (human)	IC50	0.1145	2	2
Cyclin-dependent kinase 16	Homo sapiens (human)	IC50	0.0206	2	2
Cyclin-dependent kinase 17	Homo sapiens (human)	IC50	0.0135	2	2
Cyclin-dependent kinase 18	Homo sapiens (human)	IC50	0.0587	2	2
Cyclin-dependent kinase 2	Homo sapiens (human)	IC50	1.5532	33	34
Cyclin-dependent kinase 2	Homo sapiens (human)	Ki	0.0026	2	3
Cyclin-dependent kinase 3	Homo sapiens (human)	IC50	0.0118	6	6
Cyclin-dependent kinase 4	Homo sapiens (human)	IC50	0.0575	13	14
Cyclin-dependent kinase 4	Homo sapiens (human)	Ki	0.0410	1	1
Cyclin-dependent kinase 5 activator 1	Homo sapiens (human)	IC50	0.0141	9	9
Cyclin-dependent kinase 6	Homo sapiens (human)	IC50	0.0395	7	7
Cyclin-dependent kinase 7	Homo sapiens (human)	IC50	0.2793	5	5
Cyclin-dependent kinase 8	Homo sapiens (human)	IC50	0.0105	2	2
Cyclin-dependent kinase 9	Homo sapiens (human)	IC50	0.0474	9	9
Cyclin-dependent kinase 9	Homo sapiens (human)	Ki	0.0070	1	1
Cyclin-dependent kinase-like 3	Homo sapiens (human)	IC50	1.1000	1	1
Cyclin-dependent-like kinase 5	Homo sapiens (human)	IC50	0.0141	9	9
Cyclin-G-associated kinase	Homo sapiens (human)	IC50	0.0110	1	1
Cyclin-H	Homo sapiens (human)	IC50	0.2793	5	5
Cyclin-K	Homo sapiens (human)	IC50	0.0948	5	5
Cyclin-O	Homo sapiens (human)	IC50	0.0015	4	4
Cyclin-T1	Homo sapiens (human)	IC50	0.0118	5	5
Cyclin-T1	Homo sapiens (human)	Ki	0.0070	1	1
Cyclin-T2	Homo sapiens (human)	IC50	0.0038	1	1
Cyclin-Y	Homo sapiens (human)	IC50	0.0518	8	8
Cytochrome P450 11B2, mitochondrial	Homo sapiens (human)	IC50	0.0110	1	1
Cytochrome P450 2B6	Homo sapiens (human)	Ki	0.9000	1	1
Cytochrome P450 2D6	Homo sapiens (human)	IC50	0.0002	1	1
Cytochrome P450 3A4	Homo sapiens (human)	IC50	0.0010	2	2
Cytochrome P450 3A4	Homo sapiens (human)	Ki	0.2000	1	1
Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)	IC50	0.0046	2	2
D(1A) dopamine receptor	Homo sapiens (human)	IC50	8.5020	1	1
D(1A) dopamine receptor	Sus scrofa (pig)	IC50	0.0010	1	1
D(1A) dopamine receptor	Homo sapiens (human)	Ki	4.2510	1	1
D(2) dopamine receptor	Homo sapiens (human)	IC50	13.8850	1	1
D(2) dopamine receptor	Homo sapiens (human)	Ki	4.6280	1	1
D(3) dopamine receptor	Homo sapiens (human)	IC50	1.0720	1	1
D(3) dopamine receptor	Rattus norvegicus (Norway rat)	IC50	18.1000	1	1
D(3) dopamine receptor	Homo sapiens (human)	Ki	0.3640	1	1
D(4) dopamine receptor	Homo sapiens (human)	IC50	11.1610	1	1
D(4) dopamine receptor	Homo sapiens (human)	Ki	3.9130	1	1
Death-associated protein kinase 1	Homo sapiens (human)	IC50	0.0101	6	6
Death-associated protein kinase 2	Homo sapiens (human)	IC50	0.0064	2	2
Death-associated protein kinase 3	Homo sapiens (human)	IC50	0.0026	2	2
Delta-type opioid receptor	Homo sapiens (human)	IC50	13.3390	1	1
Delta-type opioid receptor	Homo sapiens (human)	Ki	4.7020	1	1
Dipeptidyl peptidase 4	Rattus norvegicus (Norway rat)	IC50	0.0030	1	1
Discoidin domain-containing receptor 2	Homo sapiens (human)	IC50	0.0008	2	2
DNA primase	Mycobacterium tuberculosis CDC1551	IC50	8.2000	1	1
DNA-dependent protein kinase catalytic subunit	Homo sapiens (human)	IC50	1.7000	1	1
Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)	IC50	0.0552	3	3
Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)	IC50	0.2314	12	12
Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)	IC50	0.0260	2	2
Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)	IC50	0.0099	2	2
Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)	IC50	0.8630	3	3
Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)	IC50	0.0252	2	2
Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)	IC50	0.0036	3	3
Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)	IC50	0.9255	2	2
Dual specificity protein kinase CLK1	Homo sapiens (human)	IC50	0.0108	2	2
Dual specificity protein kinase CLK2	Homo sapiens (human)	IC50	1.8994	4	8
Dual specificity protein kinase CLK3	Homo sapiens (human)	IC50	0.9200	2	2
Dual specificity protein kinase CLK4	Homo sapiens (human)	IC50	0.0723	2	2
Dual specificity protein phosphatase 5	Homo sapiens (human)	Ki	0.0250	1	1
Dual specificity testis-specific protein kinase 1	Homo sapiens (human)	IC50	0.1995	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)	IC50	0.0095	4	4
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Rattus norvegicus (Norway rat)	IC50	0.0120	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)	IC50	0.0017	3	3
Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)	IC50	0.1800	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 3	Homo sapiens (human)	IC50	0.0231	2	2
Ectonucleoside triphosphate diphosphohydrolase 1	Rattus norvegicus (Norway rat)	Ki	300.0000	2	2
Ectonucleoside triphosphate diphosphohydrolase 2	Rattus norvegicus (Norway rat)	Ki	65.4000	2	2
Ectonucleoside triphosphate diphosphohydrolase 3	Rattus norvegicus (Norway rat)	Ki	12.7000	1	1
Ectonucleoside triphosphate diphosphohydrolase 8	Homo sapiens (human)	Ki	100.0000	1	1
Emopamil-binding protein-like	Homo sapiens (human)	Ki	0.0028	1	1
Ephrin type-A receptor 1	Homo sapiens (human)	IC50	0.0947	3	3
Ephrin type-A receptor 2	Homo sapiens (human)	IC50	0.1257	3	3
Ephrin type-A receptor 3	Homo sapiens (human)	IC50	0.0347	4	4
Ephrin type-A receptor 4	Homo sapiens (human)	IC50	0.0105	2	2
Ephrin type-A receptor 5	Homo sapiens (human)	IC50	0.0159	2	2
Ephrin type-A receptor 6	Homo sapiens (human)	IC50	0.0160	2	2
Ephrin type-A receptor 7	Homo sapiens (human)	IC50	0.0478	2	2
Ephrin type-A receptor 8	Homo sapiens (human)	IC50	0.1061	2	2
Ephrin type-B receptor 1	Homo sapiens (human)	IC50	0.0694	3	3
Ephrin type-B receptor 2	Homo sapiens (human)	IC50	0.1191	3	3
Ephrin type-B receptor 3	Homo sapiens (human)	IC50	1.2855	2	2
Ephrin type-B receptor 4	Homo sapiens (human)	IC50	2.1495	5	5
Epidermal growth factor receptor	Homo sapiens (human)	IC50	5.5488	35	35
Epidermal growth factor receptor	Mus musculus (house mouse)	IC50	10.0000	1	1
epidermal growth factor receptor isoform a precursor	Homo sapiens (human)	IC50	0.4467	1	1
Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)	IC50	0.9655	3	3
Estrogen receptor	Homo sapiens (human)	IC50	1.1796	41	41
Estrogen receptor	Homo sapiens (human)	Ki	0.0586	4	4
Estrogen receptor beta	Homo sapiens (human)	IC50	1.2790	22	22
Estrogen receptor beta	Homo sapiens (human)	Ki	0.0510	4	4
Estrogen-related receptor gamma	Homo sapiens (human)	IC50	0.0622	1	1
Fatty acid synthase	Homo sapiens (human)	IC50	17.8500	1	1
Fibroblast growth factor receptor 1	Homo sapiens (human)	IC50	0.0699	7	7
Fibroblast growth factor receptor 2	Homo sapiens (human)	IC50	0.0504	10	10
Fibroblast growth factor receptor 3	Homo sapiens (human)	IC50	0.0554	10	10
Fibroblast growth factor receptor 4	Homo sapiens (human)	IC50	13,900.1457	7	7
Focal adhesion kinase 1	Homo sapiens (human)	IC50	0.8255	11	11
G protein-coupled receptor kinase 4	Homo sapiens (human)	IC50	0.0914	2	2
G protein-coupled receptor kinase 5	Homo sapiens (human)	IC50	0.0490	2	2
G protein-coupled receptor kinase 6	Homo sapiens (human)	IC50	96.0236	3	4
G1/S-specific cyclin-D1	Homo sapiens (human)	IC50	0.0501	14	15
G1/S-specific cyclin-D1	Homo sapiens (human)	Ki	0.0410	1	1
G1/S-specific cyclin-D3	Homo sapiens (human)	IC50	0.0550	6	6
G1/S-specific cyclin-E1	Homo sapiens (human)	IC50	0.0249	18	19
G1/S-specific cyclin-E2	Homo sapiens (human)	IC50	0.0110	3	3
G2/mitotic-specific cyclin-B1	Homo sapiens (human)	IC50	0.0088	14	14
G2/mitotic-specific cyclin-B2	Homo sapiens (human)	IC50	0.0107	5	5
G2/mitotic-specific cyclin-B3	Homo sapiens (human)	IC50	0.0107	5	5
Glutamate receptor ionotropic, NMDA 2B	Rattus norvegicus (Norway rat)	IC50	0.0480	1	1
Glutathione S-transferase P	Homo sapiens (human)	IC50	0.5000	1	1
Glycogen synthase kinase-3 alpha	Homo sapiens (human)	IC50	0.0103	5	5
Glycogen synthase kinase-3 beta	Homo sapiens (human)	IC50	0.0591	43	45
Glycogen synthase kinase-3 beta	Rattus norvegicus (Norway rat)	IC50	0.0068	1	1
Glycogen synthase kinase-3 beta	Homo sapiens (human)	Ki	0.0220	1	1
Hepatocyte growth factor receptor	Homo sapiens (human)	IC50	0.7366	18	18
Hexokinase-4	Homo sapiens (human)	IC50	0.0006	2	2
High affinity nerve growth factor receptor	Homo sapiens (human)	IC50	91.0646	11	11
Histamine H2 receptor	Homo sapiens (human)	IC50	9.3960	1	1
Histamine H2 receptor	Homo sapiens (human)	Ki	9.2400	1	1
Homeodomain-interacting protein kinase 1	Homo sapiens (human)	IC50	1.6300	2	2
Homeodomain-interacting protein kinase 2	Homo sapiens (human)	IC50	0.3655	2	2
Homeodomain-interacting protein kinase 3	Homo sapiens (human)	IC50	0.4560	2	2
Homeodomain-interacting protein kinase 4	Homo sapiens (human)	IC50	0.2260	2	2
Inactive tyrosine-protein kinase PEAK1	Homo sapiens (human)	IC50	0.0025	2	2
Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)	IC50	0.1265	5	5
Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)	IC50	0.5561	9	9
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)	IC50	0.0003	2	2
Insulin receptor	Homo sapiens (human)	IC50	1.4890	7	7
Insulin receptor	Mus musculus (house mouse)	IC50	0.2000	1	1
Insulin receptor-related protein	Homo sapiens (human)	IC50	0.0113	2	2
Insulin-like growth factor 1 receptor	Homo sapiens (human)	IC50	1.2282	14	14
integrase, partial	Human immunodeficiency virus 1	IC50	4.9440	2	2
Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)	IC50	0.1000	1	1
Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)	IC50	0.0377	2	2
Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)	IC50	0.0122	4	4
Interstitial collagenase	Homo sapiens (human)	IC50	11.3600	1	1
Kappa-type opioid receptor	Homo sapiens (human)	IC50	15.6290	1	1
Kappa-type opioid receptor	Homo sapiens (human)	Ki	6.2520	1	1
Kinase suppressor of Ras 1	Homo sapiens (human)	IC50	6.2650	2	2
Kinase suppressor of Ras 2	Homo sapiens (human)	IC50	5.4000	2	2
Kinesin-1 heavy chain	Homo sapiens (human)	IC50	0.0015	1	1
lens epithelium-derived growth factor p75	Homo sapiens (human)	IC50	4.9440	2	2
Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)	IC50	0.0076	3	3
Leukocyte tyrosine kinase receptor	Homo sapiens (human)	IC50	0.0173	3	3
LIM domain kinase 1	Homo sapiens (human)	IC50	0.0026	2	2
LIM domain kinase 2	Homo sapiens (human)	IC50	0.0956	2	2
Lymphokine-activated killer T-cell-originated protein kinase	Homo sapiens (human)	IC50	0.0691	2	2
Lysine--tRNA ligase	Homo sapiens (human)	IC50	0.0049	2	2
Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)	IC50	0.1284	8	10
Macrophage-stimulating protein receptor	Homo sapiens (human)	IC50	0.2195	5	5
Malate dehydrogenase	Thermus thermophilus	IC50	45.0000	1	1
MAP kinase-activated protein kinase 2	Homo sapiens (human)	IC50	0.7350	10	10
MAP kinase-activated protein kinase 3	Homo sapiens (human)	IC50	2.7750	2	2
MAP kinase-activated protein kinase 5	Homo sapiens (human)	IC50	0.2120	2	2
MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)	IC50	0.0530	2	2
MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)	IC50	0.0221	3	3
MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)	IC50	0.0004	2	2
MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)	IC50	0.0001	2	2
Mast/stem cell growth factor receptor Kit	Homo sapiens (human)	IC50	0.8094	13	13
Maternal embryonic leucine zipper kinase	Homo sapiens (human)	IC50	0.0006	2	2
Megakaryocyte-associated tyrosine-protein kinase	Homo sapiens (human)	IC50	0.4420	2	2
Melanocortin receptor 3	Homo sapiens (human)	IC50	19.8560	1	1
Melanocortin receptor 3	Homo sapiens (human)	Ki	17.3290	1	1
Melanocortin receptor 4	Homo sapiens (human)	IC50	30.4810	1	1
Melanocortin receptor 4	Homo sapiens (human)	Ki	29.3080	1	1
Melanocortin receptor 5	Homo sapiens (human)	IC50	26.5290	1	1
Melanocortin receptor 5	Homo sapiens (human)	Ki	24.8860	1	1
Misshapen-like kinase 1	Homo sapiens (human)	IC50	0.0004	4	4
Mitogen-activated protein kinase 1	Homo sapiens (human)	IC50	5.5321	11	11
Mitogen-activated protein kinase 1	Mus musculus (house mouse)	IC50	10.0000	1	1
Mitogen-activated protein kinase 10	Homo sapiens (human)	IC50	5.0366	2	2
Mitogen-activated protein kinase 11	Homo sapiens (human)	IC50	1.0000	1	1
Mitogen-activated protein kinase 12	Homo sapiens (human)	IC50	0.4512	3	3
Mitogen-activated protein kinase 13	Homo sapiens (human)	IC50	0.4137	3	3
Mitogen-activated protein kinase 14	Homo sapiens (human)	IC50	3.6702	3	3
Mitogen-activated protein kinase 15	Homo sapiens (human)	IC50	0.0081	3	3
Mitogen-activated protein kinase 3	Homo sapiens (human)	IC50	9.0475	11	11
Mitogen-activated protein kinase 7	Homo sapiens (human)	IC50	5.9524	4	4
Mitogen-activated protein kinase 8	Homo sapiens (human)	IC50	2.3771	7	7
Mitogen-activated protein kinase 9	Homo sapiens (human)	IC50	3.6444	5	5
Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)	IC50	0.4380	2	2
Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)	IC50	0.1109	4	6
Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)	IC50	0.0213	4	6
Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)	IC50	0.0992	2	2
Mitogen-activated protein kinase kinase kinase 14	Homo sapiens (human)	IC50	2.3000	1	1
Mitogen-activated protein kinase kinase kinase 19	Homo sapiens (human)	IC50	0.0087	2	2
Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)	IC50	0.0335	2	2
Mitogen-activated protein kinase kinase kinase 21	Homo sapiens (human)	IC50	1.1175	2	2
Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)	IC50	0.0092	2	2
Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)	IC50	0.2150	5	5
Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)	IC50	0.2829	2	2
Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)	IC50	0.0565	5	5
Mitogen-activated protein kinase kinase kinase 8	Homo sapiens (human)	IC50	9.9500	1	1
Mitogen-activated protein kinase kinase kinase 9	Homo sapiens (human)	IC50	0.0155	4	6
Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)	IC50	0.0529	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)	IC50	0.0001	2	2
Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)	IC50	0.0005	2	2
Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)	IC50	0.0002	2	2
MO15-related protein kinase Pfmrk	Plasmodium falciparum (malaria parasite P. falciparum)	IC50	4.0000	2	2
MPI protein	Homo sapiens (human)	IC50	30.9650	1	1
Mu-type opioid receptor	Homo sapiens (human)	IC50	17.5940	1	1
Mu-type opioid receptor	Homo sapiens (human)	Ki	7.1420	1	1
Multidrug resistance-associated protein 4	Homo sapiens (human)	IC50	85.4500	1	2
Muscarinic acetylcholine receptor M1	Homo sapiens (human)	IC50	2.8290	1	1
Muscarinic acetylcholine receptor M1	Homo sapiens (human)	Ki	0.6810	1	1
Muscarinic acetylcholine receptor M2	Homo sapiens (human)	IC50	7.7930	1	1
Muscarinic acetylcholine receptor M2	Homo sapiens (human)	Ki	2.7710	1	1
Muscarinic acetylcholine receptor M3	Homo sapiens (human)	IC50	2.9740	1	1
Muscarinic acetylcholine receptor M3	Homo sapiens (human)	Ki	0.6300	1	1
Muscarinic acetylcholine receptor M4	Homo sapiens (human)	IC50	4.8170	1	1
Muscarinic acetylcholine receptor M4	Homo sapiens (human)	Ki	0.6720	1	1
Muscarinic acetylcholine receptor M5	Homo sapiens (human)	IC50	2.5850	1	1
Muscarinic acetylcholine receptor M5	Homo sapiens (human)	Ki	1.8570	1	1
Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)	IC50	0.1161	3	3
Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)	IC50	0.0147	2	2
Myosin light chain kinase 3	Homo sapiens (human)	IC50	0.1585	2	2
Myosin light chain kinase family member 4	Homo sapiens (human)	IC50	0.0537	2	2
Myosin light chain kinase, smooth muscle	Gallus gallus (chicken)	IC50	0.0000	1	1
Myosin light chain kinase, smooth muscle	Homo sapiens (human)	IC50	0.0391	4	4
Myosin light chain kinase, smooth muscle	Homo sapiens (human)	Ki	0.0200	1	1
Myosin-IIIa	Homo sapiens (human)	IC50	0.0425	2	2
Myosin-IIIb	Homo sapiens (human)	IC50	0.0058	2	2
Myotonin-protein kinase	Homo sapiens (human)	IC50	0.1735	2	2
NAD-dependent protein deacetylase HST2	Saccharomyces cerevisiae S288C	IC50	130.0000	1	2
NAD-dependent protein deacetylase sirtuin-1	Homo sapiens (human)	IC50	4.1917	11	12
NAD-dependent protein deacetylase sirtuin-2	Homo sapiens (human)	IC50	12.0222	8	9
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	Homo sapiens (human)	IC50	3.7000	1	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	Homo sapiens (human)	IC50	20.6000	8	8
NADPH oxidase 4	Homo sapiens (human)	IC50	0.0708	1	1
Neuraminidase	Influenza A virus (A/Wilson-Smith/1933(H1N1))	IC50	37.6667	3	3
Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)	IC50	0.0012	2	2
Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)	IC50	0.0137	5	5
NT-3 growth factor receptor	Homo sapiens (human)	IC50	0.0002	2	2
NUAK family SNF1-like kinase 1	Homo sapiens (human)	IC50	0.0030	4	4
NUAK family SNF1-like kinase 2	Homo sapiens (human)	IC50	0.0018	2	2
Nuclear receptor subfamily 3 group C member 3	Bos taurus (cattle)	IC50	0.9670	1	1
Nuclear receptor subfamily 3 group C member 3	Bos taurus (cattle)	Ki	0.7922	1	1
P2X purinoceptor 2	Rattus norvegicus (Norway rat)	IC50	21.9054	1	2
P2Y purinoceptor 11	Homo sapiens (human)	Ki	0.2071	2	2
P2Y purinoceptor 2	Homo sapiens (human)	IC50	75.0000	2	2
P2Y purinoceptor 6	Homo sapiens (human)	IC50	27.0000	1	1
PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)	IC50	0.0107	2	2
Peroxisome proliferator-activated receptor alpha	Homo sapiens (human)	IC50	0.0031	1	6
Peroxisome proliferator-activated receptor gamma	Homo sapiens (human)	IC50	0.5660	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)	IC50	10.0000	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)	IC50	10.0000	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)	IC50	10.0000	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)	IC50	9.5000	2	2
Phospholipase D1	Homo sapiens (human)	IC50	20.0000	1	1
Phospholipase D1	Rattus norvegicus (Norway rat)	IC50	20.0000	1	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)	IC50	0.0008	6	7
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	Homo sapiens (human)	IC50	0.0017	4	5
Phosphorylase b kinase regulatory subunit alpha, liver isoform	Homo sapiens (human)	IC50	0.0013	2	3
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform	Homo sapiens (human)	IC50	0.0013	2	3
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform	Oryctolagus cuniculus (rabbit)	IC50	0.1800	1	1
Phosphorylase b kinase regulatory subunit beta	Homo sapiens (human)	IC50	0.0013	2	3
Platelet-activating factor acetylhydrolase	Homo sapiens (human)	IC50	0.9040	1	1
Platelet-derived growth factor receptor alpha	Homo sapiens (human)	IC50	0.0007	8	8
Platelet-derived growth factor receptor alpha	Mus musculus (house mouse)	IC50	0.0020	1	1
Platelet-derived growth factor receptor beta	Homo sapiens (human)	IC50	1.1042	10	14
Platelet-derived growth factor receptor beta	Mus musculus (house mouse)	IC50	0.0020	1	1
Polyphenol oxidase 2	Agaricus bisporus	IC50	220.0000	2	2
Polyunsaturated fatty acid 5-lipoxygenase	Homo sapiens (human)	Ki	0.0844	2	2
Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)	IC50	30.9840	3	3
Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)	Ki	0.7922	1	1
Progesterone receptor	Homo sapiens (human)	IC50	50.0644	2	2
Prostaglandin G/H synthase 1	Homo sapiens (human)	IC50	4.3910	1	1
Prostaglandin G/H synthase 1	Ovis aries (sheep)	IC50	0.0560	1	1
Protein arginine N-methyltransferase 1	Homo sapiens (human)	IC50	344.8100	3	3
Protein DBF4 homolog A	Homo sapiens (human)	IC50	0.0548	2	2
Protein kinase C alpha type	Homo sapiens (human)	IC50	1.4415	35	40
Protein kinase C alpha type	Rattus norvegicus (Norway rat)	IC50	4.8922	15	16
Protein kinase C alpha type	Homo sapiens (human)	Ki	6.0000	1	1
Protein kinase C beta type	Homo sapiens (human)	IC50	1.4464	34	40
Protein kinase C beta type	Rattus norvegicus (Norway rat)	IC50	4.1212	18	19
Protein kinase C beta type	Homo sapiens (human)	Ki	6.0000	1	1
Protein kinase C beta type	Rattus norvegicus (Norway rat)	Ki	0.0190	1	1
Protein kinase C beta type	Mus musculus (house mouse)	IC50	0.2340	1	1
Protein kinase C delta type	Homo sapiens (human)	IC50	1.9547	25	30
Protein kinase C delta type	Rattus norvegicus (Norway rat)	IC50	5.5903	13	14
Protein kinase C delta type	Homo sapiens (human)	Ki	6.0000	1	1
Protein kinase C epsilon type	Homo sapiens (human)	IC50	1.8554	26	31
Protein kinase C epsilon type	Rattus norvegicus (Norway rat)	IC50	5.5903	13	14
Protein kinase C epsilon type	Homo sapiens (human)	Ki	6.0000	1	1
Protein kinase C eta type	Homo sapiens (human)	IC50	2.3938	19	24
Protein kinase C eta type	Rattus norvegicus (Norway rat)	IC50	5.5903	13	14
Protein kinase C eta type	Homo sapiens (human)	Ki	6.0000	1	1
Protein kinase C gamma type	Homo sapiens (human)	IC50	2.4314	22	24
Protein kinase C gamma type	Rattus norvegicus (Norway rat)	IC50	4.3753	16	18
Protein kinase C gamma type	Homo sapiens (human)	Ki	6.0000	1	1
Protein kinase C iota type	Homo sapiens (human)	IC50	4.1297	14	14
Protein kinase C iota type	Homo sapiens (human)	Ki	6.0000	1	1
Protein kinase C theta type	Homo sapiens (human)	IC50	2.1500	20	27
Protein kinase C theta type	Rattus norvegicus (Norway rat)	IC50	5.5903	13	14
Protein kinase C theta type	Homo sapiens (human)	Ki	6.0000	1	1
Protein kinase C zeta type	Homo sapiens (human)	IC50	3.6532	19	21
Protein kinase C zeta type	Rattus norvegicus (Norway rat)	IC50	5.5903	13	14
Protein kinase C zeta type	Homo sapiens (human)	Ki	6.0000	1	1
Protein odd-skipped-related 1	Homo sapiens (human)	IC50	0.0402	2	2
Protein-tyrosine kinase 2-beta	Homo sapiens (human)	IC50	0.0095	2	2
Protein-tyrosine kinase 6	Homo sapiens (human)	IC50	0.4840	4	4
Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)	IC50	0.7712	13	13
Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)	IC50	0.0004	6	6
Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)	IC50	0.0063	1	1
Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)	IC50	0.3642	25	25
RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)	IC50	0.5353	26	28
RAC-beta serine/threonine-protein kinase	Homo sapiens (human)	IC50	0.4119	8	10
RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)	IC50	0.3701	9	11
RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)	IC50	2.1025	5	5
Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)	IC50	1.2355	11	11
Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)	IC50	0.0106	1	1
Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)	IC50	0.1830	8	8
Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)	IC50	0.3560	2	2
Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)	GI50	0.1643	3	3
Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)	IC50	0.0399	30	30
Retinoblastoma-associated protein	Homo sapiens (human)	IC50	0.0660	1	1
Reverse transcriptase/RNaseH	Human immunodeficiency virus 1	IC50	12.2000	2	2
Rho-associated protein kinase 1	Homo sapiens (human)	IC50	1.4318	7	7
Rho-associated protein kinase 2	Bos taurus (cattle)	IC50	0.0417	2	11
Rho-associated protein kinase 2	Homo sapiens (human)	IC50	2.0036	5	5
Rhodopsin kinase GRK1	Homo sapiens (human)	IC50	0.0680	2	2
Rhodopsin kinase GRK7	Homo sapiens (human)	IC50	0.0053	2	2
Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)	IC50	0.0004	6	6
Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)	IC50	0.0002	2	2
Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)	IC50	0.0041	5	5
Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)	IC50	0.0071	2	2
Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)	IC50	0.0028	4	4
Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)	IC50	0.0001	2	2
Ribosomal protein S6 kinase beta-1	Homo sapiens (human)	IC50	0.0036	5	5
Ribosomal protein S6 kinase beta-2	Homo sapiens (human)	IC50	0.0015	2	2
RmtA	Aspergillus nidulans	IC50	5.9000	1	1
RNA-editing ligase 1, mitochondrial	Trypanosoma brucei brucei	IC50	51.3810	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	Oryctolagus cuniculus (rabbit)	IC50	1.2000	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	Homo sapiens (human)	IC50	27.0000	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	Mus musculus (house mouse)	IC50	27.0000	1	1
Serine/threonine-protein kinase 10	Homo sapiens (human)	IC50	0.0383	3	3
Serine/threonine-protein kinase 16	Homo sapiens (human)	IC50	0.2385	2	2
Serine/threonine-protein kinase 17A	Homo sapiens (human)	IC50	0.0386	3	3
Serine/threonine-protein kinase 17B	Homo sapiens (human)	IC50	0.0258	1	1
Serine/threonine-protein kinase 24	Homo sapiens (human)	IC50	0.0065	3	3
Serine/threonine-protein kinase 25	Homo sapiens (human)	IC50	0.0029	3	3
Serine/threonine-protein kinase 26	Homo sapiens (human)	IC50	0.0124	2	2
Serine/threonine-protein kinase 3	Homo sapiens (human)	IC50	0.0034	4	4
Serine/threonine-protein kinase 32B	Homo sapiens (human)	IC50	0.0374	2	2
Serine/threonine-protein kinase 32C	Homo sapiens (human)	IC50	0.2320	2	2
Serine/threonine-protein kinase 33	Homo sapiens (human)	IC50	0.0373	2	2
Serine/threonine-protein kinase 38	Homo sapiens (human)	IC50	0.0037	2	2
Serine/threonine-protein kinase 38-like	Homo sapiens (human)	IC50	0.0012	2	2
Serine/threonine-protein kinase 4	Homo sapiens (human)	IC50	0.0013	2	2
Serine/threonine-protein kinase B-raf	Homo sapiens (human)	IC50	0.0107	9	9
Serine/threonine-protein kinase BRSK1	Homo sapiens (human)	IC50	0.0007	2	2
Serine/threonine-protein kinase BRSK2	Homo sapiens (human)	IC50	0.0028	2	2
Serine/threonine-protein kinase Chk1	Homo sapiens (human)	IC50	0.1772	12	12
Serine/threonine-protein kinase Chk1	Homo sapiens (human)	Ki	0.0078	1	1
Serine/threonine-protein kinase Chk2	Homo sapiens (human)	IC50	2.7191	10	10
Serine/threonine-protein kinase D1	Homo sapiens (human)	IC50	3.8331	15	15
Serine/threonine-protein kinase D1	Homo sapiens (human)	Ki	6.0000	1	1
Serine/threonine-protein kinase D2	Homo sapiens (human)	IC50	0.0014	2	2
Serine/threonine-protein kinase D3	Homo sapiens (human)	IC50	4.1006	14	14
Serine/threonine-protein kinase D3	Homo sapiens (human)	Ki	6.0000	1	1
Serine/threonine-protein kinase DCLK1	Homo sapiens (human)	IC50	0.2670	2	2
Serine/threonine-protein kinase DCLK2	Homo sapiens (human)	IC50	0.0890	2	2
Serine/threonine-protein kinase haspin	Homo sapiens (human)	IC50	0.0422	3	3
Serine/threonine-protein kinase ICK	Homo sapiens (human)	IC50	0.0443	3	3
Serine/threonine-protein kinase LATS1	Homo sapiens (human)	IC50	0.0130	2	2
Serine/threonine-protein kinase LATS2	Homo sapiens (human)	IC50	0.0062	2	2
Serine/threonine-protein kinase LMTK3	Homo sapiens (human)	IC50	0.0265	2	3
Serine/threonine-protein kinase MAK	Homo sapiens (human)	IC50	0.0257	2	2
Serine/threonine-protein kinase MARK1	Homo sapiens (human)	IC50	0.0003	2	2
Serine/threonine-protein kinase MARK2	Homo sapiens (human)	IC50	0.0001	2	2
Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)	IC50	0.0032	2	2
Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)	IC50	0.0027	2	2
Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)	IC50	0.0005	2	2
Serine/threonine-protein kinase N1	Homo sapiens (human)	IC50	0.0025	4	4
Serine/threonine-protein kinase N2	Homo sapiens (human)	IC50	0.0055	4	4
Serine/threonine-protein kinase N3	Homo sapiens (human)	IC50	0.0105	2	2
Serine/threonine-protein kinase Nek1	Homo sapiens (human)	IC50	0.0122	3	3
Serine/threonine-protein kinase Nek11	Homo sapiens (human)	IC50	0.5210	2	2
Serine/threonine-protein kinase Nek2	Homo sapiens (human)	IC50	1.7683	3	3
Serine/threonine-protein kinase Nek3	Homo sapiens (human)	IC50	43.9500	2	2
Serine/threonine-protein kinase Nek4	Homo sapiens (human)	IC50	0.0851	2	2
Serine/threonine-protein kinase Nek5	Homo sapiens (human)	IC50	0.0864	2	2
Serine/threonine-protein kinase Nek6	Homo sapiens (human)	IC50	10.0000	1	1
Serine/threonine-protein kinase Nek8	Homo sapiens (human)	IC50	0.0263	2	2
Serine/threonine-protein kinase Nek9	Homo sapiens (human)	IC50	0.1010	2	2
Serine/threonine-protein kinase NIM1	Homo sapiens (human)	IC50	0.1102	2	2
Serine/threonine-protein kinase NLK	Homo sapiens (human)	IC50	0.0666	2	2
Serine/threonine-protein kinase PAK 1	Homo sapiens (human)	IC50	0.0004	3	3
Serine/threonine-protein kinase PAK 2	Homo sapiens (human)	IC50	2.0016	5	5
Serine/threonine-protein kinase PAK 3	Homo sapiens (human)	IC50	0.0003	2	2
Serine/threonine-protein kinase PAK 4	Homo sapiens (human)	IC50	0.0132	4	4
Serine/threonine-protein kinase PAK 5	Homo sapiens (human)	IC50	0.0039	2	2
Serine/threonine-protein kinase PAK 6	Homo sapiens (human)	IC50	0.0328	2	2
Serine/threonine-protein kinase pim-1	Homo sapiens (human)	IC50	0.0297	16	18
Serine/threonine-protein kinase pim-2	Homo sapiens (human)	IC50	0.0813	5	5
Serine/threonine-protein kinase pim-3	Homo sapiens (human)	IC50	0.0001	3	3
Serine/threonine-protein kinase PLK1	Homo sapiens (human)	IC50	17.1642	9	9
Serine/threonine-protein kinase PLK1	Homo sapiens (human)	Ki	5.6432	1	8
Serine/threonine-protein kinase PLK2	Homo sapiens (human)	IC50	0.5460	6	6
Serine/threonine-protein kinase PLK2	Homo sapiens (human)	Ki	5.6432	1	8
Serine/threonine-protein kinase PLK3	Homo sapiens (human)	IC50	5.1015	4	4
Serine/threonine-protein kinase PLK3	Homo sapiens (human)	Ki	5.6432	1	8
Serine/threonine-protein kinase PLK4	Homo sapiens (human)	IC50	0.0083	2	2
Serine/threonine-protein kinase PLK4	Homo sapiens (human)	Ki	5.0166	2	9
Serine/threonine-protein kinase receptor R3	Homo sapiens (human)	IC50	0.8500	1	1
Serine/threonine-protein kinase SBK1	Homo sapiens (human)	IC50	0.1464	2	2
Serine/threonine-protein kinase Sgk1	Homo sapiens (human)	IC50	0.0100	3	3
Serine/threonine-protein kinase Sgk2	Homo sapiens (human)	IC50	0.0158	2	2
Serine/threonine-protein kinase Sgk3	Homo sapiens (human)	IC50	0.0730	2	2
Serine/threonine-protein kinase SIK1	Homo sapiens (human)	IC50	0.0009	2	2
Serine/threonine-protein kinase SIK2	Homo sapiens (human)	IC50	0.3669	3	3
Serine/threonine-protein kinase SIK3	Homo sapiens (human)	IC50	0.1541	3	3
Serine/threonine-protein kinase STK11	Homo sapiens (human)	IC50	0.0598	2	2
Serine/threonine-protein kinase TAO1	Homo sapiens (human)	IC50	0.0008	2	2
Serine/threonine-protein kinase TAO2	Homo sapiens (human)	IC50	0.0076	2	2
Serine/threonine-protein kinase TAO3	Homo sapiens (human)	IC50	0.0017	2	2
Serine/threonine-protein kinase TBK1	Homo sapiens (human)	IC50	0.2207	3	3
Serine/threonine-protein kinase tousled-like 1	Homo sapiens (human)	IC50	0.0295	3	3
Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)	IC50	0.0035	2	2
Serine/threonine-protein kinase ULK1	Homo sapiens (human)	IC50	0.0096	2	2
Serine/threonine-protein kinase ULK2	Homo sapiens (human)	IC50	0.0032	2	2
Serine/threonine-protein kinase ULK3	Homo sapiens (human)	IC50	0.0027	2	2
Serine/threonine-protein kinase VRK1	Homo sapiens (human)	IC50	0.7430	1	1
Serine/threonine-protein kinase VRK2	Homo sapiens (human)	IC50	16.4000	1	1
Serine/threonine-protein kinase WNK1	Homo sapiens (human)	IC50	14.8000	2	2
Serine/threonine-protein kinase WNK2	Homo sapiens (human)	IC50	1.4550	2	2
Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)	IC50	0.1246	2	2
Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)	IC50	0.0416	2	2
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Homo sapiens (human)	IC50	30.5730	1	1
Sigma non-opioid intracellular receptor 1	Cavia porcellus (domestic guinea pig)	IC50	0.0067	2	2
Sigma non-opioid intracellular receptor 1	Homo sapiens (human)	IC50	0.0210	1	1
Sigma non-opioid intracellular receptor 1	Homo sapiens (human)	Ki	0.0219	2	2
Signal transducer and activator of transcription 1-alpha/beta	Homo sapiens (human)	IC50	9.1000	1	1
Signal transducer and activator of transcription 3	Mus musculus (house mouse)	IC50	100.0000	1	1
Signal transducer and activator of transcription 5A	Homo sapiens (human)	IC50	9.4000	1	1
Signal transducer and activator of transcription 5B	Homo sapiens (human)	IC50	10.4000	1	1
SNF-related serine/threonine-protein kinase	Homo sapiens (human)	IC50	0.0059	2	2
Sodium-dependent dopamine transporter	Rattus norvegicus (Norway rat)	IC50	0.0280	1	1
Sodium-dependent dopamine transporter	Homo sapiens (human)	IC50	1.8410	1	1
Sodium-dependent dopamine transporter	Homo sapiens (human)	Ki	1.4620	1	1
Sodium-dependent noradrenaline transporter	Homo sapiens (human)	IC50	1.4720	1	1
Sodium-dependent noradrenaline transporter	Homo sapiens (human)	Ki	1.4590	1	1
Sodium-dependent serotonin transporter	Homo sapiens (human)	IC50	2.3340	1	1
Sodium-dependent serotonin transporter	Homo sapiens (human)	Ki	1.2400	1	1
SRSF protein kinase 1	Homo sapiens (human)	IC50	0.0336	2	2
SRSF protein kinase 2	Homo sapiens (human)	IC50	0.2060	2	2
SRSF protein kinase 3	Homo sapiens (human)	IC50	1.7700	2	2
STE20-like serine/threonine-protein kinase	Homo sapiens (human)	IC50	0.0142	3	3
STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)	IC50	0.0158	2	2
Steroid hormone receptor ERR1	Homo sapiens (human)	IC50	0.2000	1	1
Substance-K receptor	Homo sapiens (human)	IC50	3.6700	1	1
Substance-K receptor	Homo sapiens (human)	Ki	1.2230	1	1
Substance-P receptor	Homo sapiens (human)	IC50	15.6560	1	1
Substance-P receptor	Homo sapiens (human)	Ki	8.5400	1	1
Telomerase reverse transcriptase	Homo sapiens (human)	IC50	6.9517	6	6
Testis-specific serine/threonine-protein kinase 1	Homo sapiens (human)	IC50	0.0000	2	2
Testis-specific serine/threonine-protein kinase 1	Mus musculus (house mouse)	IC50	0.0003	1	1
Testis-specific serine/threonine-protein kinase 2	Homo sapiens (human)	IC50	0.0038	2	2
Testis-specific serine/threonine-protein kinase 3	Homo sapiens (human)	IC50	0.0051	2	2
Testis-specific serine/threonine-protein kinase 6	Homo sapiens (human)	IC50	0.1525	2	2
TGF-beta receptor type-1	Homo sapiens (human)	IC50	5.7931	3	7
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1	Homo sapiens (human)	IC50	0.0370	2	2
Thioredoxin reductase 1, cytoplasmic	Homo sapiens (human)	IC50	0.0432	1	1
Thromboxane-A synthase	Homo sapiens (human)	IC50	0.9160	1	1
TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)	IC50	0.0103	4	4
Transcriptional activator protein LuxR	Aliivibrio fischeri	IC50	40.0000	1	1
Tyrosine-protein kinase ABL1	Homo sapiens (human)	GI50	20.0000	1	1
Tyrosine-protein kinase ABL1	Homo sapiens (human)	IC50	0.3101	17	17
Tyrosine-protein kinase ABL2	Homo sapiens (human)	IC50	0.0504	4	4
Tyrosine-protein kinase Blk	Homo sapiens (human)	IC50	0.0011	2	2
Tyrosine-protein kinase BTK	Homo sapiens (human)	IC50	3.1466	8	8
Tyrosine-protein kinase CSK	Homo sapiens (human)	IC50	0.2071	3	3
Tyrosine-protein kinase Fer	Homo sapiens (human)	IC50	0.0008	3	3
Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)	IC50	0.0039	3	3
Tyrosine-protein kinase Fgr	Homo sapiens (human)	IC50	0.0009	2	2
Tyrosine-protein kinase FRK	Homo sapiens (human)	IC50	0.0108	2	2
Tyrosine-protein kinase Fyn	Homo sapiens (human)	IC50	0.6353	12	12
Tyrosine-protein kinase HCK	Homo sapiens (human)	IC50	3.3350	3	3
Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)	IC50	5.3379	3	3
Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)	Ki	0.0061	1	2
Tyrosine-protein kinase JAK1	Homo sapiens (human)	IC50	1.2200	6	6
Tyrosine-protein kinase JAK2	Homo sapiens (human)	IC50	1.0014	10	10
Tyrosine-protein kinase JAK3	Homo sapiens (human)	IC50	0.1016	16	16
Tyrosine-protein kinase Lck	Homo sapiens (human)	IC50	1.4410	14	14
Tyrosine-protein kinase Lyn	Homo sapiens (human)	IC50	0.0012	12	12
Tyrosine-protein kinase Mer	Homo sapiens (human)	IC50	0.0331	3	3
Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)	IC50	0.0177	3	3
Tyrosine-protein kinase receptor UFO	Homo sapiens (human)	IC50	1.5276	6	6
Tyrosine-protein kinase Srms	Homo sapiens (human)	IC50	6.5000	2	2
Tyrosine-protein kinase SYK	Homo sapiens (human)	IC50	0.7195	14	14
Tyrosine-protein kinase Tec	Homo sapiens (human)	IC50	42.6892	3	3
Tyrosine-protein kinase TXK	Homo sapiens (human)	IC50	0.0204	2	2
Tyrosine-protein kinase Yes	Homo sapiens (human)	IC50	0.0029	4	4
Tyrosine-protein kinase ZAP-70	Homo sapiens (human)	IC50	1.1267	9	9
Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)	IC50	9.7600	1	1
ubiquitin-conjugating enzyme E2 N	Homo sapiens (human)	IC50	20.0000	1	1
Uracil nucleotide/cysteinyl leukotriene receptor	Homo sapiens (human)	IC50	100.0000	1	1
Vascular endothelial growth factor receptor 1	Homo sapiens (human)	IC50	0.0149	7	7
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	IC50	0.9991	36	40
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	Ki	0.0017	1	1
Vascular endothelial growth factor receptor 3	Homo sapiens (human)	IC50	0.4732	10	10
Xanthine dehydrogenase/oxidase	Bos taurus (cattle)	IC50	21.7300	1	1

Activation Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
26S proteasome regulatory subunit 6B	Homo sapiens (human)	Kd	30.0000	1	4
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	Homo sapiens (human)	Kd	0.0010	1	1
3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)	Kd	0.0987	3	5
5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)	Kd	4.8734	5	9
5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)	Kd	0.2808	3	5
5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)	Kd	10.5067	1	3
5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)	Kd	13.3320	1	3
7-dehydrocholesterol reductase	Homo sapiens (human)	Kd	0.0010	1	1
AarF domain-containing protein kinase 1	Homo sapiens (human)	Kd	22.0300	1	3
Actin-related protein 2	Homo sapiens (human)	Kd	30.0000	1	3
Actin-related protein 3	Homo sapiens (human)	Kd	30.0000	1	4
Activated CDC42 kinase 1	Homo sapiens (human)	Kd	4.0386	4	8
Activin receptor type-1	Homo sapiens (human)	Kd	15.1175	4	8
Activin receptor type-1B	Homo sapiens (human)	Kd	13.3272	4	8
Activin receptor type-2A	Homo sapiens (human)	Kd	9.7800	3	5
Activin receptor type-2B	Homo sapiens (human)	Kd	16.1500	4	8
Acyl-CoA dehydrogenase family member 10	Homo sapiens (human)	Kd	30.0000	1	2
Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)	Kd	30.0000	1	1
Adenosine kinase	Homo sapiens (human)	Kd	30.0000	1	3
Adenylate kinase 2, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	3
ADP/ATP translocase 2	Homo sapiens (human)	Kd	30.0000	1	3
ADP/ATP translocase 3	Homo sapiens (human)	Kd	30.0000	1	3
ALK tyrosine kinase receptor	Homo sapiens (human)	Kd	8.6963	4	7
Alpha-tocopherol transfer protein	Homo sapiens (human)	Kd	2.4200	1	1
Angiopoietin-1 receptor	Homo sapiens (human)	Kd	1.0367	4	6
Angiotensin-converting enzyme 2	Homo sapiens (human)	EC50	37.5633	1	3
Ankyrin repeat and protein kinase domain-containing protein 1	Homo sapiens (human)	Kd	6.1080	3	5
AP2-associated protein kinase 1	Homo sapiens (human)	Kd	3.3962	5	9
ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)	Kd	30.0000	1	3
ATP-dependent RNA helicase DDX1	Homo sapiens (human)	Kd	30.0000	1	3
ATP-dependent RNA helicase DDX3X	Homo sapiens (human)	Kd	30.0000	1	3
ATP-dependent RNA helicase DDX42	Homo sapiens (human)	Kd	30.0000	1	1
ATP-dependent RNA helicase DHX30	Homo sapiens (human)	Kd	30.0000	1	1
ATP-dependent translocase ABCB1	Homo sapiens (human)	EC50	56.5000	1	1
Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)	Kd	20.0000	4	10
Atypical kinase COQ8B, mitochondrial	Homo sapiens (human)	Kd	10.0000	3	5
Aurora kinase A	Homo sapiens (human)	Kd	3.1019	6	10
Aurora kinase B	Homo sapiens (human)	Kd	4.1232	4	8
Aurora kinase C	Homo sapiens (human)	Kd	0.0945	4	6
BDNF/NT-3 growth factors receptor	Homo sapiens (human)	Kd	0.1875	3	5
Beta-adrenergic receptor kinase 1	Homo sapiens (human)	Kd	30.0000	1	3
BMP-2-inducible protein kinase	Homo sapiens (human)	Kd	3.4770	5	9
Bone morphogenetic protein receptor type-1A	Homo sapiens (human)	Kd	15.9250	4	8
Bone morphogenetic protein receptor type-1B	Homo sapiens (human)	Kd	18.3617	3	6
Bone morphogenetic protein receptor type-2	Homo sapiens (human)	Kd	16.5375	4	8
Breakpoint cluster region protein	Homo sapiens (human)	Kd	30.0000	1	3
Calcium-dependent protein kinase 1	Plasmodium falciparum 3D7	Kd	0.4751	1	2
Calcium/calmodulin-dependent protein kinase kinase 1	Homo sapiens (human)	Kd	0.0650	4	6
Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)	Kd	6.6112	5	10
Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)	Kd	1.0140	4	6
Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)	Kd	0.3357	4	6
Calcium/calmodulin-dependent protein kinase type 1G	Homo sapiens (human)	Kd	0.7398	3	5
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)	Kd	0.0101	4	6
Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)	Kd	0.1059	4	6
Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)	Kd	3.4319	5	9
Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)	Kd	3.2775	6	10
Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)	Kd	15.0102	4	8
cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)	Kd	13.0683	3	7
cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)	Kd	11.3472	4	8
cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)	Kd	30.0000	1	3
cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)	Kd	0.5812	3	5
cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)	Kd	30.0000	1	3
Casein kinase I isoform alpha	Homo sapiens (human)	Kd	18.4950	3	6
Casein kinase I isoform alpha-like	Homo sapiens (human)	Kd	5.1250	2	4
Casein kinase I isoform delta	Homo sapiens (human)	Kd	15.6000	4	8
Casein kinase I isoform epsilon	Homo sapiens (human)	Kd	15.0836	5	10
Casein kinase I isoform gamma-1	Homo sapiens (human)	Kd	16.6875	4	8
Casein kinase I isoform gamma-2	Homo sapiens (human)	Kd	11.6200	5	8
Casein kinase I isoform gamma-3	Homo sapiens (human)	Kd	17.5000	4	8
Casein kinase II subunit alpha	Homo sapiens (human)	Kd	2.2952	3	5
Casein kinase II subunit alpha'	Homo sapiens (human)	Kd	15.0296	4	8
Cell division control protein 2 homolog	Plasmodium falciparum 3D7	Kd	5.4000	1	2
Cell division cycle 7-related protein kinase	Homo sapiens (human)	Kd	30.0000	1	1
cGMP-dependent protein kinase 1	Homo sapiens (human)	Kd	11.3517	4	8
cGMP-dependent protein kinase 2	Homo sapiens (human)	Kd	0.0508	3	5
Chain A, Hepatocyte growth factor receptor	Homo sapiens (human)	Kd	0.0100	1	1
Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)	Kd	30.0000	1	2
Citron Rho-interacting kinase	Homo sapiens (human)	Kd	15.0850	4	8
Cyclin-dependent kinase 1	Homo sapiens (human)	Kd	30.0000	1	3
Cyclin-dependent kinase 10	Homo sapiens (human)	Kd	30.0000	1	2
Cyclin-dependent kinase 11A	Homo sapiens (human)	Kd	10.0000	3	5
Cyclin-dependent kinase 11B	Homo sapiens (human)	Kd	10.0000	3	5
Cyclin-dependent kinase 12	Homo sapiens (human)	Kd	30.0000	1	4
Cyclin-dependent kinase 13	Homo sapiens (human)	Kd	20.0140	2	5
Cyclin-dependent kinase 14	Homo sapiens (human)	Kd	6.0640	3	5
Cyclin-dependent kinase 15	Homo sapiens (human)	Kd	6.7533	2	3
Cyclin-dependent kinase 16	Homo sapiens (human)	Kd	13.3414	5	9
Cyclin-dependent kinase 17	Homo sapiens (human)	Kd	12.8846	4	7
Cyclin-dependent kinase 18	Homo sapiens (human)	Kd	6.1080	3	5
Cyclin-dependent kinase 19	Homo sapiens (human)	Kd	4.3960	3	5
Cyclin-dependent kinase 2	Homo sapiens (human)	Kd	10.0137	5	9
Cyclin-dependent kinase 3	Homo sapiens (human)	Kd	11.2615	4	8
Cyclin-dependent kinase 4	Homo sapiens (human)	Kd	13.7605	3	8
Cyclin-dependent kinase 6	Homo sapiens (human)	Kd	20.1330	1	3
Cyclin-dependent kinase 7	Homo sapiens (human)	Kd	15.0112	4	8
Cyclin-dependent kinase 8	Homo sapiens (human)	Kd	6.2040	3	5
Cyclin-dependent kinase 9	Homo sapiens (human)	Kd	15.0250	4	8
Cyclin-dependent kinase-like 1	Homo sapiens (human)	Kd	5.1650	1	2
Cyclin-dependent kinase-like 2	Homo sapiens (human)	Kd	6.8367	2	3
Cyclin-dependent kinase-like 3	Homo sapiens (human)	Kd	8.3667	2	3
Cyclin-dependent kinase-like 5	Homo sapiens (human)	Kd	18.3900	3	6
Cyclin-dependent-like kinase 5	Homo sapiens (human)	Kd	10.1298	5	9
Cyclin-G-associated kinase	Homo sapiens (human)	Kd	6.9457	5	9
Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)	Kd	30.0000	1	1
Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	3
Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)	Kd	5.1250	4	6
dCTP pyrophosphatase 1	Homo sapiens (human)	Kd	30.0000	1	3
Death-associated protein kinase 1	Homo sapiens (human)	Kd	2.8206	3	5
Death-associated protein kinase 2	Homo sapiens (human)	Kd	0.4460	4	6
Death-associated protein kinase 3	Homo sapiens (human)	Kd	2.1129	5	8
Delta-type opioid receptor	Homo sapiens (human)	EC50	100.0000	1	1
Delta(24)-sterol reductase	Homo sapiens (human)	Kd	30.0000	1	3
Deoxycytidine kinase	Homo sapiens (human)	Kd	30.0000	1	3
Discoidin domain-containing receptor 2	Homo sapiens (human)	Kd	15.0105	4	8
DNA replication licensing factor MCM4	Homo sapiens (human)	Kd	30.0000	1	3
DNA topoisomerase 2-alpha	Homo sapiens (human)	Kd	30.0000	1	3
DNA topoisomerase 2-beta	Homo sapiens (human)	Kd	30.0000	1	3
DnaJ homolog subfamily A member 1	Homo sapiens (human)	Kd	30.0000	1	3
Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)	Kd	2.3555	1	2
Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)	Kd	11.4736	4	8
Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)	Kd	11.3162	4	8
Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)	Kd	13.2388	4	8
Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)	Kd	7.4233	4	6
Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)	Kd	14.4072	2	5
Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)	Kd	12.9550	4	9
Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)	Kd	5.0150	1	2
Dual specificity protein kinase CLK1	Homo sapiens (human)	Kd	6.7946	5	9
Dual specificity protein kinase CLK2	Homo sapiens (human)	Kd	4.0598	5	9
Dual specificity protein kinase CLK3	Homo sapiens (human)	Kd	8.4171	5	7
Dual specificity protein kinase CLK4	Homo sapiens (human)	Kd	6.8088	5	9
Dual specificity protein kinase TTK	Homo sapiens (human)	Kd	3.9128	5	8
Dual specificity testis-specific protein kinase 1	Homo sapiens (human)	Kd	15.0800	4	8
Dual specificity testis-specific protein kinase 2	Homo sapiens (human)	Kd	30.0000	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)	Kd	10.8427	3	6
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)	Kd	5.1743	4	6
Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)	Kd	6.7500	2	3
Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	3
eIF-2-alpha kinase GCN2	Homo sapiens (human)	Kd	0.0298	3	5
EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)	Kd	21.2800	1	3
Electron transfer flavoprotein subunit beta	Homo sapiens (human)	Kd	30.0000	1	2
Elongation factor Tu, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	4
Ephrin type-A receptor 1	Homo sapiens (human)	Kd	15.0750	4	8
Ephrin type-A receptor 2	Homo sapiens (human)	Kd	16.6609	5	11
Ephrin type-A receptor 3	Homo sapiens (human)	Kd	5.0182	4	6
Ephrin type-A receptor 4	Homo sapiens (human)	Kd	13.4767	5	9
Ephrin type-A receptor 5	Homo sapiens (human)	Kd	15.0340	5	10
Ephrin type-A receptor 6	Homo sapiens (human)	Kd	5.1367	4	6
Ephrin type-A receptor 7	Homo sapiens (human)	Kd	13.5500	5	9
Ephrin type-A receptor 8	Homo sapiens (human)	Kd	5.1133	4	6
Ephrin type-B receptor 1	Homo sapiens (human)	Kd	5.1783	4	6
Ephrin type-B receptor 2	Homo sapiens (human)	Kd	15.5250	4	8
Ephrin type-B receptor 3	Homo sapiens (human)	Kd	18.8889	4	9
Ephrin type-B receptor 4	Homo sapiens (human)	Kd	16.5250	4	8
Ephrin type-B receptor 6	Homo sapiens (human)	Kd	18.0586	3	7
Epidermal growth factor receptor	Homo sapiens (human)	Kd	2.9638	30	54
Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)	Kd	13.9548	4	8
Estrogen receptor	Homo sapiens (human)	EC50	1.1568	3	5
Estrogen receptor	Rattus norvegicus (Norway rat)	EC50	150.0000	1	2
Estrogen receptor beta	Homo sapiens (human)	EC50	0.9808	3	5
Estrogen receptor beta	Rattus norvegicus (Norway rat)	EC50	150.0000	1	2
Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)	Kd	18.6745	2	6
Eukaryotic translation initiation factor 5B	Homo sapiens (human)	Kd	30.0000	1	3
Exosome RNA helicase MTR4	Homo sapiens (human)	Kd	30.0000	1	3
Ferrochelatase, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	4
Fibroblast growth factor receptor 1	Homo sapiens (human)	Kd	10.5600	5	9
Fibroblast growth factor receptor 2	Homo sapiens (human)	Kd	1.2600	4	6
Fibroblast growth factor receptor 3	Homo sapiens (human)	Kd	3.2733	7	11
Fibroblast growth factor receptor 4	Homo sapiens (human)	Kd	6.1000	3	5
Focal adhesion kinase 1	Homo sapiens (human)	Kd	13.3551	5	9
G protein-coupled receptor kinase 4	Homo sapiens (human)	Kd	0.0857	2	3
G protein-coupled receptor kinase 6	Homo sapiens (human)	Kd	30.0000	1	1
General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)	Kd	30.0000	1	3
Glycine--tRNA ligase	Homo sapiens (human)	Kd	30.0000	1	3
Glycogen phosphorylase, brain form	Homo sapiens (human)	Kd	30.0000	1	3
Glycogen phosphorylase, liver form	Homo sapiens (human)	Kd	30.0000	1	3
Glycogen synthase kinase-3 alpha	Homo sapiens (human)	Kd	8.6226	4	8
Glycogen synthase kinase-3 beta	Homo sapiens (human)	Kd	8.2809	4	8
glycogen synthase kinase-3 beta isoform 1	Homo sapiens (human)	EC50	300.0000	1	2
GTP-binding nuclear protein Ran	Homo sapiens (human)	Kd	30.0000	1	3
Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)	Kd	30.0000	1	2
Heme oxygenase 2	Homo sapiens (human)	Kd	30.0000	1	4
Hepatocyte growth factor receptor	Homo sapiens (human)	Kd	7.0029	8	14
High affinity nerve growth factor receptor	Homo sapiens (human)	Kd	6.9877	5	9
Homeodomain-interacting protein kinase 1	Homo sapiens (human)	Kd	7.5667	2	3
Homeodomain-interacting protein kinase 2	Homo sapiens (human)	Kd	2.1300	2	3
Homeodomain-interacting protein kinase 3	Homo sapiens (human)	Kd	1.5583	2	3
Homeodomain-interacting protein kinase 4	Homo sapiens (human)	Kd	0.7633	2	3
Hormonally up-regulated neu tumor-associated kinase	Homo sapiens (human)	Kd	0.3667	2	3
Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)	Kd	2.5353	2	3
Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)	Kd	5.4437	2	3
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)	Kd	3.9284	4	8
Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)	Kd	30.0000	1	1
Insulin receptor	Homo sapiens (human)	Kd	13.3659	5	9
Insulin receptor-related protein	Homo sapiens (human)	Kd	6.0324	3	5
Insulin-like growth factor 1 receptor	Homo sapiens (human)	Kd	15.0525	4	8
Integrin-linked protein kinase	Homo sapiens (human)	Kd	30.0000	1	2
Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)	Kd	4.2840	3	5
Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)	Kd	18.3400	3	6
Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)	Kd	4.3224	4	8
Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)	Kd	14.0021	2	5
Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	1
Kappa-type opioid receptor	Homo sapiens (human)	EC50	100.0000	1	1
Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	0.1884	2	4
Leukocyte tyrosine kinase receptor	Homo sapiens (human)	Kd	1.8148	3	5
Leukotriene C4 synthase	Cavia porcellus (domestic guinea pig)	Kd	6.7500	1	2
LIM domain kinase 1	Homo sapiens (human)	Kd	15.1650	5	10
LIM domain kinase 2	Homo sapiens (human)	Kd	18.7111	4	9
Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)	Kd	30.0000	1	2
Lysosomal acid glucosylceramidase	Homo sapiens (human)	EC50	2.5000	1	1
Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)	Kd	0.2028	3	5
Macrophage-stimulating protein receptor	Homo sapiens (human)	Kd	18.4000	3	6
MAP kinase-activated protein kinase 2	Homo sapiens (human)	Kd	15.2200	4	8
MAP kinase-activated protein kinase 3	Homo sapiens (human)	Kd	30.0000	1	1
MAP kinase-activated protein kinase 5	Homo sapiens (human)	Kd	16.2837	4	8
MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	6.0680	3	5
MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	0.4843	4	6
MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)	Kd	3.9429	4	8
MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)	Kd	10.1276	4	9
Mast/stem cell growth factor receptor Kit	Homo sapiens (human)	Kd	0.1948	22	37
Maternal embryonic leucine zipper kinase	Homo sapiens (human)	Kd	7.6236	4	8
Megakaryocyte-associated tyrosine-protein kinase	Homo sapiens (human)	Kd	6.7533	2	3
Membrane-associated progesterone receptor component 1	Homo sapiens (human)	Kd	30.0000	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)	Kd	17.5000	4	8
Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	3.4467	2	3
Midasin	Homo sapiens (human)	Kd	30.0000	1	4
Misshapen-like kinase 1	Homo sapiens (human)	Kd	6.0764	3	5
Mitogen-activated protein kinase 1	Homo sapiens (human)	Kd	16.8250	4	8
Mitogen-activated protein kinase 10	Homo sapiens (human)	Kd	11.2622	5	9
Mitogen-activated protein kinase 11	Homo sapiens (human)	Kd	17.5000	4	8
Mitogen-activated protein kinase 12	Homo sapiens (human)	Kd	5.0293	4	6
Mitogen-activated protein kinase 13	Homo sapiens (human)	Kd	6.7467	2	3
Mitogen-activated protein kinase 14	Homo sapiens (human)	Kd	17.5000	4	8
Mitogen-activated protein kinase 15	Homo sapiens (human)	Kd	11.2796	4	8
Mitogen-activated protein kinase 3	Homo sapiens (human)	Kd	17.1000	4	8
Mitogen-activated protein kinase 4	Homo sapiens (human)	Kd	10.0000	3	5
Mitogen-activated protein kinase 6	Homo sapiens (human)	Kd	8.6200	3	5
Mitogen-activated protein kinase 7	Homo sapiens (human)	Kd	15.4000	4	8
Mitogen-activated protein kinase 8	Homo sapiens (human)	Kd	8.3012	5	9
Mitogen-activated protein kinase 9	Homo sapiens (human)	Kd	10.8884	5	9
Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)	Kd	18.3917	3	6
Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)	Kd	2.3368	3	5
Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)	Kd	3.2272	5	10
Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)	Kd	5.7500	1	2
Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)	Kd	1.9367	2	3
Mitogen-activated protein kinase kinase kinase 15	Homo sapiens (human)	Kd	6.6675	2	3
Mitogen-activated protein kinase kinase kinase 19	Homo sapiens (human)	Kd	0.0103	2	3
Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)	Kd	10.7334	3	6
Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)	Kd	17.5000	4	8
Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)	Kd	15.5367	3	6
Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)	Kd	16.7818	5	11
Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)	Kd	9.0632	6	10
Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)	Kd	13.4325	3	6
Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)	Kd	0.1090	2	3
Mitogen-activated protein kinase kinase kinase 9	Homo sapiens (human)	Kd	0.0130	3	5
Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)	Kd	8.3451	4	8
Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)	Kd	10.8566	3	6
Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)	Kd	7.8438	4	8
Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)	Kd	4.1996	4	8
Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)	Kd	7.0617	5	9
Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)	Kd	30.0000	1	3
Mu-type opioid receptor	Homo sapiens (human)	EC50	100.0000	1	1
Multifunctional protein ADE2	Homo sapiens (human)	Kd	30.0000	1	3
Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)	Kd	6.0344	3	5
Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)	Kd	5.0387	4	6
Myosin light chain kinase 3	Homo sapiens (human)	Kd	12.5076	2	5
Myosin light chain kinase family member 4	Homo sapiens (human)	Kd	0.5720	3	5
Myosin light chain kinase, smooth muscle	Gallus gallus (chicken)	Kd	5.0700	1	2
Myosin light chain kinase, smooth muscle	Homo sapiens (human)	Kd	11.5833	5	9
Myosin-14	Homo sapiens (human)	Kd	30.0000	1	3
Myosin-IIIa	Homo sapiens (human)	Kd	6.2000	3	5
Myosin-IIIb	Homo sapiens (human)	Kd	6.1200	3	5
Myotonin-protein kinase	Homo sapiens (human)	Kd	2.2814	3	5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)	Kd	30.0000	1	3
Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)	Kd	3.9255	4	8
Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)	Kd	10.3602	6	11
NT-3 growth factor receptor	Homo sapiens (human)	Kd	1.0268	3	5
NUAK family SNF1-like kinase 1	Homo sapiens (human)	Kd	0.0264	3	5
NUAK family SNF1-like kinase 2	Homo sapiens (human)	Kd	11.2736	4	8
Nuclear receptor subfamily 1 group I member 2	Homo sapiens (human)	EC50	1.3000	1	1
Nucleolar GTP-binding protein 1	Homo sapiens (human)	Kd	19.0990	1	2
Obg-like ATPase 1	Homo sapiens (human)	Kd	30.0000	1	1
P2X purinoceptor 1	Rattus norvegicus (Norway rat)	EC50	1.0000	1	1
P2X purinoceptor 2	Rattus norvegicus (Norway rat)	EC50	10.4000	1	1
P2X purinoceptor 3	Homo sapiens (human)	EC50	8.9500	2	2
P2X purinoceptor 4	Rattus norvegicus (Norway rat)	EC50	100.0000	1	1
P2X purinoceptor 5	Rattus norvegicus (Norway rat)	EC50	4.0000	1	1
P2X purinoceptor 6	Rattus norvegicus (Norway rat)	EC50	100.0000	1	1
P2X purinoceptor 7	Homo sapiens (human)	EC50	92.0000	1	1
P2Y purinoceptor 1	Meleagris gallopavo (turkey)	EC50	10.0000	1	1
P2Y purinoceptor 11	Homo sapiens (human)	EC50	16.0000	1	1
P2Y purinoceptor 12	Rattus norvegicus (Norway rat)	EC50	4.0000	1	1
P2Y purinoceptor 2	Homo sapiens (human)	EC50	48.0000	1	1
P2Y purinoceptor 4	Homo sapiens (human)	EC50	100.0000	1	1
PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)	Kd	30.0000	1	1
Peripheral plasma membrane protein CASK	Homo sapiens (human)	Kd	5.0095	1	2
Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)	Kd	30.0000	1	1
Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)	Kd	30.0000	1	3
Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)	Kd	30.0000	1	3
Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)	Kd	30.0000	1	1
Phosphatidylinositol 4-kinase beta	Homo sapiens (human)	Kd	6.8200	2	3
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)	Kd	7.1333	2	3
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	Homo sapiens (human)	Kd	0.5233	2	3
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)	Kd	0.2032	3	5
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)	Kd	6.3500	1	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)	Kd	9.1697	21	33
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)	Kd	10.0000	2	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)	Kd	10.0000	2	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)	Kd	7.2667	2	3
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)	Kd	30.0000	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)	Kd	0.1928	3	5
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)	Kd	22.0000	2	5
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)	Kd	7.4405	5	9
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	Homo sapiens (human)	Kd	0.3320	4	6
Platelet-derived growth factor receptor alpha	Homo sapiens (human)	Kd	0.1920	3	5
Platelet-derived growth factor receptor beta	Homo sapiens (human)	Kd	6.8458	5	9
Poly [ADP-ribose] polymerase tankyrase-2	Homo sapiens (human)	Kd	0.1200	1	1
POsterior Segregation	Caenorhabditis elegans	EC50	15.8050	1	1
Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)	Kd	30.0000	1	3
Procathepsin L	Homo sapiens (human)	EC50	37.5633	1	3
Prostaglandin G/H synthase 2	Homo sapiens (human)	Kd	0.6650	1	2
Protein delta homolog 1	Homo sapiens (human)	Kd	10.0000	1	1
Protein kinase C alpha type	Homo sapiens (human)	Kd	6.6126	3	5
Protein kinase C beta type	Homo sapiens (human)	Kd	20.0080	1	3
Protein kinase C delta type	Homo sapiens (human)	Kd	10.1076	4	9
Protein kinase C epsilon type	Homo sapiens (human)	Kd	0.3241	3	5
Protein kinase C eta type	Homo sapiens (human)	Kd	0.1759	3	5
Protein kinase C iota type	Homo sapiens (human)	Kd	20.0052	2	5
Protein kinase C theta type	Homo sapiens (human)	Kd	7.8488	4	8
Protein kinase C zeta type	Homo sapiens (human)	Kd	30.0000	1	1
Protein-tyrosine kinase 2-beta	Homo sapiens (human)	Kd	7.9184	4	8
Protein-tyrosine kinase 6	Homo sapiens (human)	Kd	17.1778	4	9
Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)	Kd	2.7441	11	19
Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)	Kd	0.2700	3	5
Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)	Kd	9.3880	6	10
Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)	Kd	30.0000	1	4
Pyridoxal kinase	Homo sapiens (human)	Kd	30.0000	1	3
Rab-like protein 3	Homo sapiens (human)	Kd	30.0000	1	3
RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)	EC50	0.4600	2	2
RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)	Kd	11.6112	4	8
RAC-beta serine/threonine-protein kinase	Homo sapiens (human)	Kd	11.5535	4	8
RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)	Kd	14.3425	4	8
RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)	Kd	10.0000	3	5
Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)	Kd	30.0000	1	1
Ras-related protein Rab-10	Homo sapiens (human)	Kd	30.0000	1	3
Ras-related protein Rab-27A	Homo sapiens (human)	Kd	30.0000	1	3
Ras-related protein Rab-6A	Homo sapiens (human)	Kd	30.0000	1	4
Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)	Kd	8.0380	3	5
Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)	Kd	10.0000	2	3
Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)	Kd	2.3233	2	3
Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	10.0000	3	5
Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	11.7807	5	9
Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)	Kd	30.0000	1	3
Receptor-interacting serine/threonine-protein kinase 4	Homo sapiens (human)	Kd	6.7033	2	3
Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)	Kd	0.7704	25	40
Replicase polyprotein 1a	Severe acute respiratory syndrome-related coronavirus	EC50	37.5633	1	3
Replicase polyprotein 1ab	Betacoronavirus England 1	EC50	37.5633	1	3
Replicase polyprotein 1ab	Human coronavirus 229E	EC50	37.5633	1	3
Replicase polyprotein 1ab	Severe acute respiratory syndrome coronavirus 2	EC50	37.5633	1	3
Replicase polyprotein 1ab	Severe acute respiratory syndrome-related coronavirus	EC50	37.5633	1	3
Rho-associated protein kinase 1	Homo sapiens (human)	Kd	17.6000	3	6
Rho-associated protein kinase 2	Homo sapiens (human)	Kd	15.7667	3	6
Rhodopsin kinase GRK1	Homo sapiens (human)	Kd	0.0570	2	3
Rhodopsin kinase GRK7	Homo sapiens (human)	Kd	0.0323	2	3
Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)	Kd	6.7585	7	13
Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)	Kd	2.9189	7	11
Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)	Kd	5.3517	5	9
Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)	Kd	7.4063	7	13
Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)	Kd	7.6966	8	14
Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)	Kd	3.4852	7	13
Ribosomal protein S6 kinase beta-1	Homo sapiens (human)	Kd	16.8836	3	6
Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)	Kd	21.3437	1	3
RNA cytidine acetyltransferase	Homo sapiens (human)	Kd	30.0000	1	3
S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)	Kd	30.0000	1	3
Septin-9	Homo sapiens (human)	Kd	30.0000	1	3
Serine/threonine-protein kinase 10	Homo sapiens (human)	Kd	6.9168	5	9
Serine/threonine-protein kinase 16	Homo sapiens (human)	Kd	10.1756	5	9
Serine/threonine-protein kinase 17A	Homo sapiens (human)	Kd	0.9585	4	6
Serine/threonine-protein kinase 17B	Homo sapiens (human)	Kd	2.3613	4	6
Serine/threonine-protein kinase 24	Homo sapiens (human)	Kd	12.8914	4	7
Serine/threonine-protein kinase 25	Homo sapiens (human)	Kd	1.1240	3	5
Serine/threonine-protein kinase 26	Homo sapiens (human)	Kd	15.0350	4	8
Serine/threonine-protein kinase 3	Homo sapiens (human)	Kd	7.5654	4	8
Serine/threonine-protein kinase 3	Mus musculus (house mouse)	Kd	0.0001	1	1
Serine/threonine-protein kinase 32A	Homo sapiens (human)	Kd	1.2065	1	2
Serine/threonine-protein kinase 32B	Homo sapiens (human)	Kd	6.0392	3	5
Serine/threonine-protein kinase 32C	Homo sapiens (human)	Kd	6.1240	3	5
Serine/threonine-protein kinase 33	Homo sapiens (human)	Kd	4.0387	3	5
Serine/threonine-protein kinase 35	Homo sapiens (human)	Kd	6.7133	2	3
Serine/threonine-protein kinase 36	Homo sapiens (human)	Kd	7.7167	4	6
Serine/threonine-protein kinase 38	Homo sapiens (human)	Kd	12.5140	3	4
Serine/threonine-protein kinase 38-like	Homo sapiens (human)	Kd	7.7838	5	8
Serine/threonine-protein kinase 4	Homo sapiens (human)	Kd	6.6807	5	9
Serine/threonine-protein kinase A-Raf	Homo sapiens (human)	Kd	30.0000	1	4
Serine/threonine-protein kinase ATR	Homo sapiens (human)	Kd	30.0000	1	2
Serine/threonine-protein kinase B-raf	Homo sapiens (human)	Kd	14.6154	7	13
Serine/threonine-protein kinase BRSK1	Homo sapiens (human)	Kd	0.7304	3	5
Serine/threonine-protein kinase BRSK2	Homo sapiens (human)	Kd	0.3914	3	5
Serine/threonine-protein kinase Chk1	Homo sapiens (human)	Kd	8.0036	4	8
Serine/threonine-protein kinase Chk2	Homo sapiens (human)	Kd	6.6913	2	3
Serine/threonine-protein kinase D1	Homo sapiens (human)	Kd	6.0108	3	5
Serine/threonine-protein kinase D2	Homo sapiens (human)	Kd	9.8842	4	8
Serine/threonine-protein kinase D3	Homo sapiens (human)	Kd	8.7093	4	8
Serine/threonine-protein kinase DCLK1	Homo sapiens (human)	Kd	6.0440	3	5
Serine/threonine-protein kinase DCLK2	Homo sapiens (human)	Kd	6.0292	3	5
Serine/threonine-protein kinase DCLK3	Homo sapiens (human)	Kd	6.0068	3	5
Serine/threonine-protein kinase ICK	Homo sapiens (human)	Kd	10.5210	3	5
Serine/threonine-protein kinase LATS1	Homo sapiens (human)	Kd	7.9314	4	8
Serine/threonine-protein kinase LATS2	Homo sapiens (human)	Kd	1.3268	3	5
Serine/threonine-protein kinase MAK	Homo sapiens (human)	Kd	7.5333	2	3
Serine/threonine-protein kinase MARK1	Homo sapiens (human)	Kd	0.1036	3	5
Serine/threonine-protein kinase MARK2	Homo sapiens (human)	Kd	3.5294	5	9
Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)	Kd	15.0142	4	8
Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)	Kd	15.0105	4	8
Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)	Kd	12.8677	4	7
Serine/threonine-protein kinase mTOR	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase N1	Homo sapiens (human)	Kd	0.4297	4	8
Serine/threonine-protein kinase N2	Homo sapiens (human)	Kd	7.5514	4	8
Serine/threonine-protein kinase N3	Homo sapiens (human)	Kd	30.0000	1	2
Serine/threonine-protein kinase Nek1	Homo sapiens (human)	Kd	15.2150	4	8
Serine/threonine-protein kinase Nek11	Homo sapiens (human)	Kd	6.5500	1	2
Serine/threonine-protein kinase Nek2	Homo sapiens (human)	Kd	13.5822	5	9
Serine/threonine-protein kinase Nek3	Homo sapiens (human)	Kd	22.0000	2	5
Serine/threonine-protein kinase Nek4	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase Nek5	Homo sapiens (human)	Kd	6.3240	3	5
Serine/threonine-protein kinase Nek6	Homo sapiens (human)	Kd	10.0000	3	5
Serine/threonine-protein kinase Nek7	Homo sapiens (human)	Kd	6.5005	4	6
Serine/threonine-protein kinase Nek9	Homo sapiens (human)	Kd	14.7667	5	9
Serine/threonine-protein kinase NIM1	Homo sapiens (human)	Kd	6.7133	2	3
Serine/threonine-protein kinase NLK	Homo sapiens (human)	Kd	15.0550	4	8
Serine/threonine-protein kinase OSR1	Homo sapiens (human)	Kd	6.8133	2	3
Serine/threonine-protein kinase PAK 1	Homo sapiens (human)	Kd	1.0339	4	6
Serine/threonine-protein kinase PAK 2	Homo sapiens (human)	Kd	12.3383	4	8
Serine/threonine-protein kinase PAK 3	Homo sapiens (human)	Kd	0.6125	4	6
Serine/threonine-protein kinase PAK 4	Homo sapiens (human)	Kd	12.0365	5	10
Serine/threonine-protein kinase PAK 5	Homo sapiens (human)	Kd	5.0009	4	6
Serine/threonine-protein kinase PAK 6	Homo sapiens (human)	Kd	11.2502	5	8
Serine/threonine-protein kinase pim-1	Homo sapiens (human)	Kd	6.4139	6	11
Serine/threonine-protein kinase pim-2	Homo sapiens (human)	Kd	12.5675	5	9
Serine/threonine-protein kinase pim-3	Homo sapiens (human)	Kd	0.3362	3	5
Serine/threonine-protein kinase PknB	Mycobacterium tuberculosis H37Rv	Kd	5.0440	1	2
Serine/threonine-protein kinase PLK1	Homo sapiens (human)	Kd	6.0760	3	5
Serine/threonine-protein kinase PLK2	Homo sapiens (human)	Kd	6.7333	2	3
Serine/threonine-protein kinase PLK3	Homo sapiens (human)	Kd	6.3640	3	5
Serine/threonine-protein kinase PLK4	Homo sapiens (human)	Kd	3.3874	5	9
Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)	Kd	0.1100	2	3
Serine/threonine-protein kinase receptor R3	Homo sapiens (human)	Kd	10.0000	3	5
Serine/threonine-protein kinase RIO1	Homo sapiens (human)	Kd	0.7720	3	5
Serine/threonine-protein kinase RIO2	Homo sapiens (human)	Kd	0.1947	2	3
Serine/threonine-protein kinase RIO3	Homo sapiens (human)	Kd	0.2651	4	9
Serine/threonine-protein kinase SBK1	Homo sapiens (human)	Kd	5.0016	1	2
Serine/threonine-protein kinase Sgk3	Homo sapiens (human)	Kd	0.7017	1	2
Serine/threonine-protein kinase SIK1	Homo sapiens (human)	Kd	0.0969	3	5
Serine/threonine-protein kinase SIK2	Homo sapiens (human)	Kd	6.9877	4	9
Serine/threonine-protein kinase SIK3	Homo sapiens (human)	Kd	10.7039	3	6
Serine/threonine-protein kinase STK11	Homo sapiens (human)	Kd	11.3965	4	8
Serine/threonine-protein kinase TAO1	Homo sapiens (human)	Kd	15.5368	4	7
Serine/threonine-protein kinase TAO2	Homo sapiens (human)	Kd	20.0024	2	5
Serine/threonine-protein kinase TAO3	Homo sapiens (human)	Kd	18.3334	3	6
Serine/threonine-protein kinase TBK1	Homo sapiens (human)	Kd	5.2274	3	6
Serine/threonine-protein kinase TNNI3K	Homo sapiens (human)	Kd	6.4000	3	5
Serine/threonine-protein kinase tousled-like 1	Homo sapiens (human)	Kd	6.0108	3	5
Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)	Kd	6.0064	3	5
Serine/threonine-protein kinase ULK1	Homo sapiens (human)	Kd	18.3350	3	6
Serine/threonine-protein kinase ULK2	Homo sapiens (human)	Kd	6.6669	2	3
Serine/threonine-protein kinase ULK3	Homo sapiens (human)	Kd	10.4514	3	6
Serine/threonine-protein kinase ULK3	Mus musculus (house mouse)	Kd	0.0030	1	1
Serine/threonine-protein kinase VRK2	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)	Kd	10.7733	3	6
Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)	Kd	20.3027	1	3
SNF-related serine/threonine-protein kinase	Homo sapiens (human)	Kd	5.0450	1	2
Sodium-dependent noradrenaline transporter	Homo sapiens (human)	EC50	14.0470	1	1
Spike glycoprotein	Betacoronavirus England 1	EC50	37.5633	1	3
Spike glycoprotein	Severe acute respiratory syndrome-related coronavirus	EC50	37.5633	1	3
SRSF protein kinase 1	Homo sapiens (human)	Kd	0.0274	3	5
SRSF protein kinase 2	Homo sapiens (human)	Kd	0.2248	3	5
SRSF protein kinase 3	Homo sapiens (human)	Kd	0.0777	2	3
STE20-like serine/threonine-protein kinase	Homo sapiens (human)	Kd	7.1072	5	9
STE20-related kinase adapter protein alpha	Homo sapiens (human)	Kd	30.0000	1	3
STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)	Kd	6.7100	2	3
streptokinase A precursor	Streptococcus pyogenes M1 GAS	EC50	78.0860	2	2
Structural maintenance of chromosomes protein 1A	Homo sapiens (human)	Kd	30.0000	1	3
Structural maintenance of chromosomes protein 2	Homo sapiens (human)	Kd	30.0000	1	3
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	3
Testis-specific serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	2.8896	3	5
TGF-beta receptor type-1	Homo sapiens (human)	Kd	14.0199	4	9
TGF-beta receptor type-2	Homo sapiens (human)	Kd	17.5000	4	8
Thyroid hormone receptor-associated protein 3	Homo sapiens (human)	Kd	30.0000	1	1
TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)	Kd	3.8737	5	9
Transient receptor potential cation channel subfamily M member 6	Homo sapiens (human)	Kd	10.0000	1	2
Transmembrane protease serine 2	Homo sapiens (human)	EC50	37.5633	1	3
Tubulin alpha-1A chain	Rattus norvegicus (Norway rat)	Kd	1.9350	1	2
Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)	Kd	30.0000	1	3
Tyrosine-protein kinase ABL1	Homo sapiens (human)	Kd	5.8525	39	63
Tyrosine-protein kinase ABL2	Homo sapiens (human)	Kd	13.3756	5	9
Tyrosine-protein kinase Blk	Homo sapiens (human)	Kd	0.3060	3	5
Tyrosine-protein kinase BTK	Homo sapiens (human)	Kd	10.2997	5	9
Tyrosine-protein kinase CSK	Homo sapiens (human)	Kd	14.7200	5	10
Tyrosine-protein kinase Fer	Homo sapiens (human)	Kd	4.1242	5	9
Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)	Kd	16.6718	4	9
Tyrosine-protein kinase Fgr	Homo sapiens (human)	Kd	0.3757	4	6
Tyrosine-protein kinase FRK	Homo sapiens (human)	Kd	10.8389	5	9
Tyrosine-protein kinase Fyn	Homo sapiens (human)	Kd	10.7130	5	9
Tyrosine-protein kinase HCK	Homo sapiens (human)	Kd	10.2458	5	9
Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)	Kd	6.0076	3	5
Tyrosine-protein kinase JAK1	Homo sapiens (human)	Kd	12.8496	6	11
Tyrosine-protein kinase JAK2	Homo sapiens (human)	Kd	0.0523	4	6
Tyrosine-protein kinase JAK3	Homo sapiens (human)	Kd	0.0116	3	5
Tyrosine-protein kinase Lck	Homo sapiens (human)	Kd	12.0920	5	10
Tyrosine-protein kinase Lyn	Homo sapiens (human)	Kd	11.4322	5	9
Tyrosine-protein kinase Mer	Homo sapiens (human)	Kd	5.5363	4	7
Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)	Kd	0.8660	3	5
Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)	Kd	5.1080	4	6
Tyrosine-protein kinase receptor UFO	Homo sapiens (human)	Kd	0.3747	3	5
Tyrosine-protein kinase Srms	Homo sapiens (human)	Kd	6.2960	3	5
Tyrosine-protein kinase SYK	Homo sapiens (human)	Kd	4.4522	5	9
Tyrosine-protein kinase Tec	Homo sapiens (human)	Kd	15.3250	4	8
Tyrosine-protein kinase TXK	Homo sapiens (human)	Kd	6.0920	3	5
Tyrosine-protein kinase Yes	Homo sapiens (human)	Kd	10.3337	5	9
Tyrosine-protein kinase ZAP-70	Homo sapiens (human)	Kd	1.5776	3	5
U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)	Kd	30.0000	1	3
Uncharacterized aarF domain-containing protein kinase 5	Homo sapiens (human)	Kd	30.0000	1	2
Uncharacterized protein FLJ45252	Homo sapiens (human)	Kd	10.1047	1	3
Uncharacterized serine/threonine-protein kinase SBK3	Homo sapiens (human)	Kd	6.6750	2	3
Vascular endothelial growth factor receptor 1	Homo sapiens (human)	Kd	0.3300	3	5
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	Kd	1.7183	4	6
Vascular endothelial growth factor receptor 3	Homo sapiens (human)	Kd	0.3495	4	6
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	3
Wee1-like protein kinase	Homo sapiens (human)	Kd	14.7250	4	8
Wee1-like protein kinase 2	Homo sapiens (human)	Kd	10.0000	2	3
Zinc finger protein mex-5	Caenorhabditis elegans	EC50	14.0470	1	1

Other Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
cAMP-dependent protein kinase catalytic subunit alpha isoform Calpha1	Homo sapiens (human)	AC50	0.1260	1	1
Estrogen receptor	Rattus norvegicus (Norway rat)	A50	0.0200	1	1
Estrogen receptor	Homo sapiens (human)	DC50	0.0910	1	1
Estrogen receptor beta	Rattus norvegicus (Norway rat)	A50	0.0200	1	1
interferon gamma precursor	Homo sapiens (human)	AC50	35.2400	1	1
Neuraminidase	Influenza A virus (A/Wilson-Smith/1933(H1N1))	Kiuc	43.0000	1	1
Prolyl 4-hydroxylase, beta polypeptide	Homo sapiens (human)	AC50	9.8000	2	2
Receptor-type tyrosine-protein phosphatase beta	Homo sapiens (human)	Kis	125.7000	1	1
UDP-glucuronosyltransferase 1A4	Homo sapiens (human)	Km	32.0000	1	1

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EC 2.7.11.13 (protein kinase C) inhibitor

Members (20)

Research

Studies (58,960)

Study Types

Protein Targets (949)

Potency Measurements

Inhibition Measurements

Activation Measurements

Other Measurements