Page last updated: 2024-08-05 15:13:59

EC 2.7.11.13 (protein kinase C) inhibitor

An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of protein kinase C (EC 2.7.11.13).

ChEBI ID: 37700

Members (20)

MemberDefinitionClass
1-(5-isoquinolinesulfonyl)-2-methylpiperazine1-(5-isoquinolinesulfonyl)-2-methylpiperazine; 5-(2-methylpiperazine-1-sulfonyl)isoquinoline
1-(5-isoquinolinesulfonyl)-2-methylpiperazineA member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.1-(5-isoquinolinesulfonyl)-2-methylpiperazine; 5-(2-methylpiperazine-1-sulfonyl)isoquinoline
1-(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochlorideA hydrochloride salt prepared from anileridine and two molar equivalents of hydrogen chloride.1-(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride
bisindolylmaleimide iiibisindolylmaleimide III
chelerythrineA benzophenanthridine alkaloid isolated from the root of Zanthoxylum simulans, Chelidonium majus L., and other Papaveraceae.chelerythrine
d-alpha tocopherolAn alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils.(R,R,R)-alpha-tocopherol
forapinA 26-membered polypeptide consisting of Gly, Ile, Gly, Ala, Val, Leu, Lys, Val, Leu, Thr, Thr, Gly, Leu, Pro, Ala, Leu, Ile, Ser, Trp, Ile, Lys, Arg, Lys, Arg, Gln and Gln-NH2 residues joined in sequence. It is the principal active component of bee venom.melittin
go 6976Goe 6976
hispidinFungal metabolite first found in basidiomycete Inonotus hispidus (formerly Polyporus hispidus).hispidin
mephentermineA 2-aminooctadecane-1,3-diol having (2S,3R)-configuration.sphinganine
midostaurinAn organic heterooctacyclic compound that is the N-benzoyl derivative of staurosporine.midostaurin
myricitrinA glycosyloxyflavone that consists of myricetin attached to a alpha-L-rhamnopyranosyl residue at position 3 via a glycosidic linkage. Isolated from Myrica cerifera, it exhibits anti-allergic activity.myricitrin
norathyriolA member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3, 6 and 7. Isolated from Garcinia mangostana and Maclura pomifera, it exhibits inhibitory activity against protein kinase C.norathyriol
ro 31-8220Ro 31-8220
sf 2370A organic heterooctacyclic compound that is a potent inhibitor of protein kinase C and is isolated from Nocardiopsis sp K-252aK-252a
sotrastaurinA member of the class of maleimides that is maleimide which is substituted at position 3 by an indol-3-yl group and at position 4 by a quinazolin-4-yl group, which in turn is substituted at position 2 by a 4-methylpiperazin-1-yl group. It is a potent and selective inhibitor of protein kinase C and has been investigated as an immunosuppresant in renal transplant patients.sotrastaurin
staurosporinestaurosporine
suraminA member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.suramin
suramin sodiumAn organic sodium salt that is the hexasodium salt of suramin. It is an FDA approved drug for African sleeping sickness and river blindness.suramin sodium
tamoxifentamoxifen

Research

Studies (58,960)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-199010,839 (18.38)18.7374
1990's14,154 (24.01)18.2507
2000's16,686 (28.30)29.6817
2010's13,915 (23.60)24.3611
2020's3,366 (5.71)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials5,314 (8.45%)5.53%
Reviews5,917 (9.41%)6.00%
Case Studies1,807 (2.87%)4.05%
Observational108 (0.17%)0.25%
Other49,707 (79.08%)84.16%

Protein Targets (949)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1Homo sapiens (human)Potency13.948012
15-lipoxygenase, partialHomo sapiens (human)Potency19.952611
2,3-bisphosphoglycerate-independent phosphoglycerate mutaseLeishmania major strain FriedlinPotency15.101411
67.9K proteinVaccinia virusPotency14.439127
acetylcholinesteraseHomo sapiens (human)Potency62.959424
acid sphingomyelinaseHomo sapiens (human)Potency89.125111
activating transcription factor 6Homo sapiens (human)Potency41.472025
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency26.183616
Alpha-synucleinHomo sapiens (human)Potency18.356411
apical membrane antigen 1, AMA1Plasmodium falciparum 3D7Potency35.481311
AR proteinHomo sapiens (human)Potency26.9855715
arylsulfatase AHomo sapiens (human)Potency11.727213
ATAD5 protein, partialHomo sapiens (human)Potency10.483534
Ataxin-2Homo sapiens (human)Potency34.606425
ATP-dependent phosphofructokinaseTrypanosoma brucei brucei TREU927Potency15.450024
ATPase family AAA domain-containing protein 5Homo sapiens (human)Potency61.317212
atrial natriuretic peptide receptor 1 precursorHomo sapiens (human)Potency16.944111
atrial natriuretic peptide receptor 2 precursorHomo sapiens (human)Potency14.689211
Bloom syndrome protein isoform 1Homo sapiens (human)Potency3.397523
bromodomain adjacent to zinc finger domain 2BHomo sapiens (human)Potency58.241713
caspase 7, apoptosis-related cysteine proteaseHomo sapiens (human)Potency44.301612
caspase-1 isoform alpha precursorHomo sapiens (human)Potency39.810711
caspase-3Cricetulus griseus (Chinese hamster)Potency39.483912
caspase-3Homo sapiens (human)Potency44.301612
Caspase-7Cricetulus griseus (Chinese hamster)Potency39.483912
Cellular tumor antigen p53Homo sapiens (human)Potency41.565227
cellular tumor antigen p53 isoform aHomo sapiens (human)Potency22.383127
Chain A, 2-oxoglutarate OxygenaseHomo sapiens (human)Potency13.678812
Chain A, ATP-DEPENDENT DNA HELICASE Q1Homo sapiens (human)Potency22.799338
Chain A, Beta-lactamaseEscherichia coli K-12Potency5.011911
Chain A, Breast cancer type 1 susceptibility proteinHomo sapiens (human)Potency14.219112
Chain A, CruzipainTrypanosoma cruziPotency25.204113
Chain A, Ferritin light chainEquus caballus (horse)Potency29.835716
Chain A, HADH2 proteinHomo sapiens (human)Potency16.534125
Chain A, JmjC domain-containing histone demethylation protein 3AHomo sapiens (human)Potency38.145612
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASEHomo sapiens (human)Potency18.5190314
Chain A, Putative fructose-1,6-bisphosphate aldolaseGiardia intestinalisPotency12.258615
Chain A, TYROSYL-DNA PHOSPHODIESTERASEHomo sapiens (human)Potency12.5787213
Chain B, HADH2 proteinHomo sapiens (human)Potency16.534125
chromobox protein homolog 1Homo sapiens (human)Potency36.888425
cytochrome P450 2C19 precursorHomo sapiens (human)Potency10.000011
cytochrome P450 2C9 precursorHomo sapiens (human)Potency39.810711
cytochrome P450 2D6 isoform 1Homo sapiens (human)Potency21.561713
cytochrome P450 3A4 isoform 1Homo sapiens (human)Potency31.622826
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency37.908311
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency6.025012
D(1A) dopamine receptorHomo sapiens (human)Potency6.020022
D(1A) dopamine receptorSus scrofa (pig)Potency18.985012
Disintegrin and metalloproteinase domain-containing protein 17Homo sapiens (human)Potency25.118911
DNA polymerase betaHomo sapiens (human)Potency3.705113
DNA polymerase eta isoform 1Homo sapiens (human)Potency13.609613
DNA polymerase III, partialBacillus subtilisPotency25.935613
DNA polymerase iota isoform a (long)Homo sapiens (human)Potency43.311425
DNA polymerase kappa isoform 1Homo sapiens (human)Potency5.537215
dual specificity mitogen-activated protein kinase kinase 1Homo sapiens (human)Potency0.100011
endonuclease IVEscherichia coliPotency14.570423
epidermal growth factor receptor isoform a precursorHomo sapiens (human)Potency0.199644
estrogen nuclear receptor alphaHomo sapiens (human)Potency19.61721021
estrogen receptor 2 (ER beta)Homo sapiens (human)Potency54.291834
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency29.9130917
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency14.9433113
EWS/FLI fusion proteinHomo sapiens (human)Potency5.2205414
farnesoid X nuclear receptorHomo sapiens (human)Potency49.592433
flap endonuclease 1Homo sapiens (human)Potency8.564036
Fumarate hydrataseHomo sapiens (human)Potency24.021915
GABA theta subunitRattus norvegicus (Norway rat)Potency31.622813
galactokinaseHomo sapiens (human)Potency17.782811
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)Potency31.622813
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)Potency31.622813
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)Potency31.622813
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)Potency31.622813
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)Potency31.622813
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)Potency31.622813
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)Potency31.622813
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)Potency31.622813
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)Potency31.622813
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)Potency31.622813
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)Potency31.622813
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)Potency31.622813
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)Potency31.622813
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)Potency31.622813
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)Potency31.622813
gemininHomo sapiens (human)Potency19.717234
GLI family zinc finger 3Homo sapiens (human)Potency20.840824
GLS proteinHomo sapiens (human)Potency8.634225
glucocerebrosidaseHomo sapiens (human)Potency26.261716
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency27.981436
glucokinase regulatory proteinHomo sapiens (human)Potency12.589311
Glutamate receptor 1Rattus norvegicus (Norway rat)Potency8.912511
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency5.924323
Glutamate receptor 3Rattus norvegicus (Norway rat)Potency8.912511
Glutamate receptor 4Rattus norvegicus (Norway rat)Potency8.912511
GTP-binding nuclear protein Ran isoform 1Homo sapiens (human)Potency1.458111
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)Homo sapiens (human)Potency11.755424
heat shock protein beta-1Homo sapiens (human)Potency38.093823
hexokinase-4 isoform 1Homo sapiens (human)Potency12.589311
Histamine H2 receptorCavia porcellus (domestic guinea pig)Potency14.2797215
histone acetyltransferase KAT2A isoform 1Homo sapiens (human)Potency29.903314
Histone H2A.xCricetulus griseus (Chinese hamster)Potency46.087624
histone-lysine N-methyltransferase 2A isoform 2 precursorHomo sapiens (human)Potency11.034412
huntingtin isoform 2Homo sapiens (human)Potency10.000011
hypothetical protein, conservedTrypanosoma bruceiPotency50.118711
hypoxia-inducible factor 1 alpha subunitHomo sapiens (human)Potency45.907924
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)Homo sapiens (human)Potency22.106024
IDH1Homo sapiens (human)Potency17.025513
importin subunit beta-1 isoform 1Homo sapiens (human)Potency1.458111
Inositol monophosphatase 1Rattus norvegicus (Norway rat)Potency5.735614
Integrin alpha-IIbHomo sapiens (human)Potency20.211714
Integrin beta-3Homo sapiens (human)Potency20.211714
Interferon betaHomo sapiens (human)Potency12.6366118
lamin isoform A-delta10Homo sapiens (human)Potency8.327426
lethal factor (plasmid)Bacillus anthracis str. A2012Potency23.110313
LuciferasePhotinus pyralis (common eastern firefly)Potency28.898433
lysosomal alpha-glucosidase preproproteinHomo sapiens (human)Potency3.162311
M-phase phosphoprotein 8Homo sapiens (human)Potency7.643515
Microtubule-associated protein tauHomo sapiens (human)Potency16.1684222
mitogen-activated protein kinase 1Homo sapiens (human)Potency31.622811
muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)Potency18.533122
muscleblind-like protein 1 isoform 1Homo sapiens (human)Potency11.904812
NFKB1 protein, partialHomo sapiens (human)Potency5.787524
nonstructural protein 1Influenza A virus (A/WSN/1933(H1N1))Potency6.309611
NPC intracellular cholesterol transporter 1 precursorHomo sapiens (human)Potency58.047912
Nrf2Homo sapiens (human)Potency16.360111
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency35.618423
nuclear factor erythroid 2-related factor 2 isoform 2Homo sapiens (human)Potency23.109311
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_aHomo sapiens (human)Potency27.594125
nuclear receptor ROR-gamma isoform 1Mus musculus (house mouse)Potency14.523229
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency68.694334
Ornithine decarboxylaseRattus norvegicus (Norway rat)Potency31.622811
ParkinHomo sapiens (human)Potency16.688124
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1Homo sapiens (human)Potency25.903122
peripheral myelin protein 22Rattus norvegicus (Norway rat)Potency36.125411
peripheral myelin protein 22 isoform 1Homo sapiens (human)Potency72.520612
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency58.932134
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency54.941022
phosphoglycerate kinaseTrypanosoma brucei brucei TREU927Potency1.694411
phosphopantetheinyl transferaseBacillus subtilisPotency46.2919215
plasminogen precursorMus musculus (house mouse)Potency8.912511
Platelet-activating factor receptorHomo sapiens (human)Potency14.219112
polyproteinZika virusPotency24.021915
polyunsaturated fatty acid lipoxygenase ALOX12Homo sapiens (human)Potency12.589311
Polyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)Potency7.897016
potassium voltage-gated channel subfamily H member 2 isoform dHomo sapiens (human)Potency3.548111
PPM1D proteinHomo sapiens (human)Potency12.6366112
pregnane X nuclear receptorHomo sapiens (human)Potency12.021412
progesterone receptorHomo sapiens (human)Potency68.910434
pyruvate kinaseLeishmania mexicana mexicanaPotency0.794322
pyruvate kinase PKM isoform bHomo sapiens (human)Potency31.622822
RAF proto-oncogene serine/threonine-protein kinase isoform bHomo sapiens (human)Potency0.177811
Rap guanine nucleotide exchange factor 3Homo sapiens (human)Potency47.068522
RAR-related orphan receptor gammaMus musculus (house mouse)Potency29.361824
ras-related protein Rab-9AHomo sapiens (human)Potency79.369613
regulator of G-protein signaling 4Homo sapiens (human)Potency7.250518
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency48.413638
retinoid X nuclear receptor alphaHomo sapiens (human)Potency38.609723
serine/threonine-protein kinase mTOR isoform 1Homo sapiens (human)Potency15.800547
serine/threonine-protein kinase PLK1Homo sapiens (human)Potency37.685811
Single-stranded DNA cytosine deaminaseHomo sapiens (human)Potency32.983816
SMAD family member 2Homo sapiens (human)Potency59.353635
SMAD family member 3Homo sapiens (human)Potency59.353635
Smad3Homo sapiens (human)Potency0.707911
snurportin-1Homo sapiens (human)Potency1.458111
survival motor neuron protein isoform dHomo sapiens (human)Potency11.801216
TDP1 proteinHomo sapiens (human)Potency20.0614220
thioredoxin reductaseRattus norvegicus (Norway rat)Potency33.604528
ThrombopoietinHomo sapiens (human)Potency2.988224
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency12.125935
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency70.794611
thyroid stimulating hormone receptorHomo sapiens (human)Potency39.900948
thyrotropin-releasing hormone receptorHomo sapiens (human)Potency27.318524
transcriptional regulator ERG isoform 3Homo sapiens (human)Potency11.220211
tumor susceptibility gene 101 proteinHomo sapiens (human)Potency50.118711
Type-1A angiotensin II receptor Rattus norvegicus (Norway rat)Potency0.100011
Type-1B angiotensin II receptorRattus norvegicus (Norway rat)Potency0.100011
Type-2 angiotensin II receptorRattus norvegicus (Norway rat)Potency0.100011
tyrosine-protein kinase YesHomo sapiens (human)Potency0.109111
ubiquitin carboxyl-terminal hydrolase 2 isoform aHomo sapiens (human)Potency25.118911
urokinase plasminogen activator surface receptor precursorMus musculus (house mouse)Potency8.912511
urokinase-type plasminogen activator precursorMus musculus (house mouse)Potency8.912511
USP1 protein, partialHomo sapiens (human)Potency32.575415
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency20.518824
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency61.644822
vitamin D3 receptor isoform VDRAHomo sapiens (human)Potency53.416517
Voltage-dependent calcium channel gamma-2 subunitMus musculus (house mouse)Potency4.430212

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrialHomo sapiens (human)IC502.233733
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)IC500.012011
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)Ki0.005011
3-phosphoinositide-dependent protein kinase 1Homo sapiens (human)IC502.4422410
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)IC5012.160011
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)Ki6.949011
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)IC5012.160011
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)Ki6.949011
5-hydroxytryptamine receptor 2AHomo sapiens (human)IC504.801011
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)IC504.000011
5-hydroxytryptamine receptor 2AHomo sapiens (human)Ki1.372011
5-hydroxytryptamine receptor 2BHomo sapiens (human)IC502.084011
5-hydroxytryptamine receptor 2BHomo sapiens (human)Ki1.326011
5-hydroxytryptamine receptor 2CHomo sapiens (human)IC500.460011
5-hydroxytryptamine receptor 2CHomo sapiens (human)Ki0.241011
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)IC500.460011
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)Ki0.241011
5-hydroxytryptamine receptor 6Homo sapiens (human)IC502.679011
5-hydroxytryptamine receptor 6Homo sapiens (human)Ki1.142522
5'-AMP-activated protein kinase subunit beta-1Homo sapiens (human)IC503.036315
5'-AMP-activated protein kinase subunit gamma-1Homo sapiens (human)IC503.036315
7-dehydrocholesterol reductaseHomo sapiens (human)IC500.012011
7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)IC50100.000011
AcetylcholinesteraseHomo sapiens (human)IC501.450011
Activated CDC42 kinase 1Homo sapiens (human)IC500.029822
Activin receptor type-1Homo sapiens (human)IC504.197726
Activin receptor type-1BHomo sapiens (human)IC509.118011
Acyl-CoA desaturase 1Mus musculus (house mouse)IC503.400011
Adenosine receptor A1Homo sapiens (human)IC5023.767011
Adenosine receptor A1Homo sapiens (human)Ki13.864011
Adenosine receptor A2aHomo sapiens (human)IC507.099011
Adenosine receptor A2aHomo sapiens (human)Ki3.985011
Adenosine receptor A3Homo sapiens (human)IC503.701011
Adenosine receptor A3Homo sapiens (human)Ki2.092011
Aldehyde oxidaseHomo sapiens (human)IC500.002412
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)IC501.472011
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)Ki1.459011
ALK tyrosine kinase receptorHomo sapiens (human)IC500.55971818
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)IC503.701011
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)Ki2.092011
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)IC503.701011
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)Ki2.092011
Alpha-1D adrenergic receptorHomo sapiens (human)IC504.982011
Alpha-1D adrenergic receptorHomo sapiens (human)Ki2.449011
Alpha-2A adrenergic receptorHomo sapiens (human)IC501.935011
Alpha-2A adrenergic receptorHomo sapiens (human)Ki0.726011
Alpha-2B adrenergic receptorHomo sapiens (human)IC503.518011
Alpha-2B adrenergic receptorHomo sapiens (human)Ki1.606011
Amine oxidase [flavin-containing] AHomo sapiens (human)IC5012.775022
Amine oxidase [flavin-containing] AHomo sapiens (human)Ki0.220011
Amine oxidase [flavin-containing] BHomo sapiens (human)IC5020.000011
Amine oxidase [flavin-containing] BRattus norvegicus (Norway rat)IC500.002515
Androgen receptorRattus norvegicus (Norway rat)IC5017.342322
Androgen receptorRattus norvegicus (Norway rat)Ki15.108011
Angiopoietin-1 receptorHomo sapiens (human)IC509,916.735266
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)IC500.967011
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)Ki0.792211
Angiotensin-converting enzyme Homo sapiens (human)IC50530.800011
Angiotensin-converting enzyme Homo sapiens (human)Ki250.200011
AP2-associated protein kinase 1Homo sapiens (human)IC500.200011
Aromatic-L-amino-acid decarboxylaseHomo sapiens (human)IC501,280.000011
Aspartyl/asparaginyl beta-hydroxylaseHomo sapiens (human)IC508.782544
ATP-binding cassette sub-family C member 3Homo sapiens (human)IC50133.000012
ATP-dependent 6-phosphofructokinaseTrypanosoma brucei bruceiIC503.000011
ATP-dependent translocase ABCB1Homo sapiens (human)IC5019.725044
ATP-dependent translocase ABCB1Homo sapiens (human)Ki0.100011
Aurora kinase AHomo sapiens (human)IC500.01142424
Aurora kinase BHomo sapiens (human)IC500.33061212
Aurora kinase CHomo sapiens (human)IC500.002222
B2 bradykinin receptorHomo sapiens (human)IC5020.356011
B2 bradykinin receptorHomo sapiens (human)Ki12.048011
Bcl-2-like protein 1Homo sapiens (human)IC50100.000011
BDNF/NT-3 growth factors receptorHomo sapiens (human)IC500.000433
Beta-1 adrenergic receptorHomo sapiens (human)IC5017.289011
Beta-1 adrenergic receptorHomo sapiens (human)Ki9.984011
Beta-3 adrenergic receptorHomo sapiens (human)IC507.703011
Beta-3 adrenergic receptorHomo sapiens (human)Ki5.778011
Beta-adrenergic receptor kinase 1Homo sapiens (human)IC501.159522
Beta-adrenergic receptor kinase 2Homo sapiens (human)IC500.856022
Bile salt export pumpHomo sapiens (human)IC5050.585757
Bone morphogenetic protein receptor type-1AHomo sapiens (human)IC504.288011
Bone morphogenetic protein receptor type-2Homo sapiens (human)IC501.940022
Breakpoint cluster region proteinHomo sapiens (human)GI5020.000011
Breakpoint cluster region proteinHomo sapiens (human)IC500.094544
C-8 sterol isomeraseSaccharomyces cerevisiae S288CKi1.500011
Calcium-dependent protein kinase 1Plasmodium falciparum K1IC500.240011
Calcium/calmodulin-dependent protein kinase kinase 1Homo sapiens (human)IC500.035922
Calcium/calmodulin-dependent protein kinase kinase 2Homo sapiens (human)IC500.024622
Calcium/calmodulin-dependent protein kinase type 1Homo sapiens (human)IC500.003222
Calcium/calmodulin-dependent protein kinase type 1BHomo sapiens (human)IC500.004422
Calcium/calmodulin-dependent protein kinase type 1DHomo sapiens (human)IC500.000322
Calcium/calmodulin-dependent protein kinase type 1GHomo sapiens (human)IC500.004622
Calcium/calmodulin-dependent protein kinase type II subunit alphaHomo sapiens (human)IC500.002266
Calcium/calmodulin-dependent protein kinase type II subunit alphaRattus norvegicus (Norway rat)IC500.059011
Calcium/calmodulin-dependent protein kinase type II subunit betaHomo sapiens (human)IC500.001877
Calcium/calmodulin-dependent protein kinase type II subunit deltaHomo sapiens (human)IC500.144088
Calcium/calmodulin-dependent protein kinase type II subunit gammaHomo sapiens (human)IC500.002655
Calcium/calmodulin-dependent protein kinase type IVHomo sapiens (human)IC500.147522
cAMP-dependent protein kinase Oryctolagus cuniculus (rabbit)IC500.000011
cAMP-dependent protein kinase catalytic subunit alphaBos taurus (cattle)IC500.1281719
cAMP-dependent protein kinase catalytic subunit alphaHomo sapiens (human)IC500.26071414
cAMP-dependent protein kinase catalytic subunit alphaHomo sapiens (human)Ki3.000011
cAMP-dependent protein kinase catalytic subunit alpha Rattus norvegicus (Norway rat)IC500.166244
cAMP-dependent protein kinase catalytic subunit betaHomo sapiens (human)IC500.28291313
cAMP-dependent protein kinase catalytic subunit betaHomo sapiens (human)Ki3.000011
cAMP-dependent protein kinase catalytic subunit gammaHomo sapiens (human)IC500.30431212
cAMP-dependent protein kinase catalytic subunit gammaHomo sapiens (human)Ki3.000011
cAMP-dependent protein kinase catalytic subunit PRKXHomo sapiens (human)IC500.001422
Canalicular multispecific organic anion transporter 1Homo sapiens (human)IC50133.000012
Cannabinoid receptor 1Rattus norvegicus (Norway rat)IC500.010011
Casein kinase I isoform alphaHomo sapiens (human)IC503.412044
Casein kinase I isoform alpha-likeHomo sapiens (human)IC501.840022
Casein kinase I isoform deltaHomo sapiens (human)IC501.400011
Casein kinase I isoform epsilonHomo sapiens (human)IC501.400011
Casein kinase I isoform gamma-1Homo sapiens (human)IC505.336733
Casein kinase I isoform gamma-2Homo sapiens (human)IC501.946733
Casein kinase I isoform gamma-3Homo sapiens (human)IC502.675022
Casein kinase II subunit alphaHomo sapiens (human)IC5027.604344
Casein kinase II subunit alpha Mus musculus (house mouse)IC5010.000011
Casein kinase II subunit alpha'Homo sapiens (human)IC5021.617255
Casein kinase II subunit alpha'Mus musculus (house mouse)IC5010.000011
Casein kinase II subunit alpha'-interacting proteinMus musculus (house mouse)IC5010.000011
Casein kinase II subunit betaHomo sapiens (human)IC5035.600033
Casein kinase II subunit betaMus musculus (house mouse)IC5010.000011
Cathepsin BHomo sapiens (human)IC5030.000011
CDK-activating kinase assembly factor MAT1Homo sapiens (human)IC500.121644
Cell division cycle 7-related protein kinaseHomo sapiens (human)IC500.054822
cGMP-dependent protein kinase 1 Homo sapiens (human)IC500.002755
cGMP-dependent protein kinase 2Homo sapiens (human)IC500.016122
Chain A, CES1 proteinHomo sapiens (human)Ki15.200011
Chain A, Glycogen Synthase Kinase-3 BetaHomo sapiens (human)IC500.015012
Chain A, Protein kinase C, theta typeHomo sapiens (human)Ki0.000311
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1Homo sapiens (human)IC500.010012
Chain A, Serine/threonine-protein kinase Chk1Homo sapiens (human)Ki0.007813
Chain A, Serine/threonine-protein kinase pknBMycobacterium tuberculosisIC501.000011
Chain A, Serine/threonine-protein kinase TAO2Rattus norvegicus (Norway rat)IC503.000011
Chain A, Tyrosine-protein kinase SYKHomo sapiens (human)IC500.012011
Chain A, Tyrosine-protein kinase ZAP-70Homo sapiens (human)IC500.055811
Chain B, Glycogen Synthase Kinase-3 BetaHomo sapiens (human)IC500.015011
Chain E, Camp-dependent Protein KinaseBos taurus (cattle)Ki0.008011
Chain X, Proto-oncogene tyrosine-protein kinase FynHomo sapiens (human)IC500.004811
CholinesteraseHomo sapiens (human)IC508.580011
Chymotrypsinogen BHomo sapiens (human)IC5020.000011
Citron Rho-interacting kinaseHomo sapiens (human)IC500.749022
Coiled-coil domain-containing protein 6Homo sapiens (human)IC500.002211
Cyclin-A1Homo sapiens (human)IC500.461055
Cyclin-A1Homo sapiens (human)Ki0.004011
Cyclin-A2Homo sapiens (human)IC504.03071313
Cyclin-A2Homo sapiens (human)Ki0.002623
Cyclin-CHomo sapiens (human)IC500.010522
Cyclin-dependent kinase 1Homo sapiens (human)IC500.00752323
Cyclin-dependent kinase 1Homo sapiens (human)Ki0.002012
Cyclin-dependent kinase 1 Mus musculus (house mouse)IC500.008011
Cyclin-dependent kinase 12Homo sapiens (human)IC500.053011
Cyclin-dependent kinase 13Homo sapiens (human)IC500.057011
Cyclin-dependent kinase 14Homo sapiens (human)IC500.114522
Cyclin-dependent kinase 16Homo sapiens (human)IC500.020622
Cyclin-dependent kinase 17Homo sapiens (human)IC500.013522
Cyclin-dependent kinase 18Homo sapiens (human)IC500.058722
Cyclin-dependent kinase 2Homo sapiens (human)IC501.55323334
Cyclin-dependent kinase 2Homo sapiens (human)Ki0.002623
Cyclin-dependent kinase 3Homo sapiens (human)IC500.011866
Cyclin-dependent kinase 4Homo sapiens (human)IC500.05751314
Cyclin-dependent kinase 4Homo sapiens (human)Ki0.041011
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)IC500.014199
Cyclin-dependent kinase 6Homo sapiens (human)IC500.039577
Cyclin-dependent kinase 7Homo sapiens (human)IC500.279355
Cyclin-dependent kinase 8Homo sapiens (human)IC500.010522
Cyclin-dependent kinase 9Homo sapiens (human)IC500.047499
Cyclin-dependent kinase 9Homo sapiens (human)Ki0.007011
Cyclin-dependent kinase-like 3Homo sapiens (human)IC501.100011
Cyclin-dependent-like kinase 5 Homo sapiens (human)IC500.014199
Cyclin-G-associated kinaseHomo sapiens (human)IC500.011011
Cyclin-HHomo sapiens (human)IC500.279355
Cyclin-KHomo sapiens (human)IC500.094855
Cyclin-OHomo sapiens (human)IC500.001544
Cyclin-T1Homo sapiens (human)IC500.011855
Cyclin-T1Homo sapiens (human)Ki0.007011
Cyclin-T2Homo sapiens (human)IC500.003811
Cyclin-YHomo sapiens (human)IC500.051888
Cytochrome P450 11B2, mitochondrialHomo sapiens (human)IC500.011011
Cytochrome P450 2B6Homo sapiens (human)Ki0.900011
Cytochrome P450 2D6Homo sapiens (human)IC500.000211
Cytochrome P450 3A4Homo sapiens (human)IC500.001022
Cytochrome P450 3A4Homo sapiens (human)Ki0.200011
Cytoplasmic tyrosine-protein kinase BMXHomo sapiens (human)IC500.004622
D(1A) dopamine receptorHomo sapiens (human)IC508.502011
D(1A) dopamine receptorSus scrofa (pig)IC500.001011
D(1A) dopamine receptorHomo sapiens (human)Ki4.251011
D(2) dopamine receptorHomo sapiens (human)IC5013.885011
D(2) dopamine receptorHomo sapiens (human)Ki4.628011
D(3) dopamine receptorHomo sapiens (human)IC501.072011
D(3) dopamine receptorRattus norvegicus (Norway rat)IC5018.100011
D(3) dopamine receptorHomo sapiens (human)Ki0.364011
D(4) dopamine receptorHomo sapiens (human)IC5011.161011
D(4) dopamine receptorHomo sapiens (human)Ki3.913011
Death-associated protein kinase 1Homo sapiens (human)IC500.010166
Death-associated protein kinase 2Homo sapiens (human)IC500.006422
Death-associated protein kinase 3Homo sapiens (human)IC500.002622
Delta-type opioid receptorHomo sapiens (human)IC5013.339011
Delta-type opioid receptorHomo sapiens (human)Ki4.702011
Dipeptidyl peptidase 4Rattus norvegicus (Norway rat)IC500.003011
Discoidin domain-containing receptor 2Homo sapiens (human)IC500.000822
DNA primaseMycobacterium tuberculosis CDC1551IC508.200011
DNA-dependent protein kinase catalytic subunitHomo sapiens (human)IC501.700011
Dual serine/threonine and tyrosine protein kinaseHomo sapiens (human)IC500.055233
Dual specificity mitogen-activated protein kinase kinase 1Homo sapiens (human)IC500.23141212
Dual specificity mitogen-activated protein kinase kinase 2Homo sapiens (human)IC500.026022
Dual specificity mitogen-activated protein kinase kinase 3Homo sapiens (human)IC500.009922
Dual specificity mitogen-activated protein kinase kinase 4Homo sapiens (human)IC500.863033
Dual specificity mitogen-activated protein kinase kinase 5Homo sapiens (human)IC500.025222
Dual specificity mitogen-activated protein kinase kinase 6Homo sapiens (human)IC500.003633
Dual specificity mitogen-activated protein kinase kinase 7Homo sapiens (human)IC500.925522
Dual specificity protein kinase CLK1Homo sapiens (human)IC500.010822
Dual specificity protein kinase CLK2Homo sapiens (human)IC501.899448
Dual specificity protein kinase CLK3Homo sapiens (human)IC500.920022
Dual specificity protein kinase CLK4Homo sapiens (human)IC500.072322
Dual specificity protein phosphatase 5Homo sapiens (human)Ki0.025011
Dual specificity testis-specific protein kinase 1Homo sapiens (human)IC500.199522
Dual specificity tyrosine-phosphorylation-regulated kinase 1AHomo sapiens (human)IC500.009544
Dual specificity tyrosine-phosphorylation-regulated kinase 1ARattus norvegicus (Norway rat)IC500.012011
Dual specificity tyrosine-phosphorylation-regulated kinase 1BHomo sapiens (human)IC500.001733
Dual specificity tyrosine-phosphorylation-regulated kinase 2Homo sapiens (human)IC500.180022
Dual specificity tyrosine-phosphorylation-regulated kinase 3Homo sapiens (human)IC500.023122
Ectonucleoside triphosphate diphosphohydrolase 1Rattus norvegicus (Norway rat)Ki300.000022
Ectonucleoside triphosphate diphosphohydrolase 2Rattus norvegicus (Norway rat)Ki65.400022
Ectonucleoside triphosphate diphosphohydrolase 3 Rattus norvegicus (Norway rat)Ki12.700011
Ectonucleoside triphosphate diphosphohydrolase 8Homo sapiens (human)Ki100.000011
Emopamil-binding protein-likeHomo sapiens (human)Ki0.002811
Ephrin type-A receptor 1Homo sapiens (human)IC500.094733
Ephrin type-A receptor 2Homo sapiens (human)IC500.125733
Ephrin type-A receptor 3Homo sapiens (human)IC500.034744
Ephrin type-A receptor 4Homo sapiens (human)IC500.010522
Ephrin type-A receptor 5Homo sapiens (human)IC500.015922
Ephrin type-A receptor 6Homo sapiens (human)IC500.016022
Ephrin type-A receptor 7Homo sapiens (human)IC500.047822
Ephrin type-A receptor 8Homo sapiens (human)IC500.106122
Ephrin type-B receptor 1Homo sapiens (human)IC500.069433
Ephrin type-B receptor 2Homo sapiens (human)IC500.119133
Ephrin type-B receptor 3Homo sapiens (human)IC501.285522
Ephrin type-B receptor 4Homo sapiens (human)IC502.149555
Epidermal growth factor receptorHomo sapiens (human)IC505.54883535
Epidermal growth factor receptorMus musculus (house mouse)IC5010.000011
epidermal growth factor receptor isoform a precursorHomo sapiens (human)IC500.446711
Epithelial discoidin domain-containing receptor 1Homo sapiens (human)IC500.965533
Estrogen receptorHomo sapiens (human)IC501.17964141
Estrogen receptorHomo sapiens (human)Ki0.058644
Estrogen receptor betaHomo sapiens (human)IC501.27902222
Estrogen receptor betaHomo sapiens (human)Ki0.051044
Estrogen-related receptor gammaHomo sapiens (human)IC500.062211
Fatty acid synthaseHomo sapiens (human)IC5017.850011
Fibroblast growth factor receptor 1Homo sapiens (human)IC500.069977
Fibroblast growth factor receptor 2Homo sapiens (human)IC500.05041010
Fibroblast growth factor receptor 3Homo sapiens (human)IC500.05541010
Fibroblast growth factor receptor 4Homo sapiens (human)IC5013,900.145777
Focal adhesion kinase 1Homo sapiens (human)IC500.82551111
G protein-coupled receptor kinase 4Homo sapiens (human)IC500.091422
G protein-coupled receptor kinase 5Homo sapiens (human)IC500.049022
G protein-coupled receptor kinase 6Homo sapiens (human)IC5096.023634
G1/S-specific cyclin-D1Homo sapiens (human)IC500.05011415
G1/S-specific cyclin-D1Homo sapiens (human)Ki0.041011
G1/S-specific cyclin-D3Homo sapiens (human)IC500.055066
G1/S-specific cyclin-E1Homo sapiens (human)IC500.02491819
G1/S-specific cyclin-E2Homo sapiens (human)IC500.011033
G2/mitotic-specific cyclin-B1Homo sapiens (human)IC500.00881414
G2/mitotic-specific cyclin-B2Homo sapiens (human)IC500.010755
G2/mitotic-specific cyclin-B3Homo sapiens (human)IC500.010755
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)IC500.048011
Glutathione S-transferase PHomo sapiens (human)IC500.500011
Glycogen synthase kinase-3 alphaHomo sapiens (human)IC500.010355
Glycogen synthase kinase-3 betaHomo sapiens (human)IC500.05914345
Glycogen synthase kinase-3 betaRattus norvegicus (Norway rat)IC500.006811
Glycogen synthase kinase-3 betaHomo sapiens (human)Ki0.022011
Hepatocyte growth factor receptorHomo sapiens (human)IC500.73661818
Hexokinase-4Homo sapiens (human)IC500.000622
High affinity nerve growth factor receptorHomo sapiens (human)IC5091.06461111
Histamine H2 receptorHomo sapiens (human)IC509.396011
Histamine H2 receptorHomo sapiens (human)Ki9.240011
Homeodomain-interacting protein kinase 1Homo sapiens (human)IC501.630022
Homeodomain-interacting protein kinase 2Homo sapiens (human)IC500.365522
Homeodomain-interacting protein kinase 3Homo sapiens (human)IC500.456022
Homeodomain-interacting protein kinase 4Homo sapiens (human)IC500.226022
Inactive tyrosine-protein kinase PEAK1Homo sapiens (human)IC500.002522
Inhibitor of nuclear factor kappa-B kinase subunit alphaHomo sapiens (human)IC500.126555
Inhibitor of nuclear factor kappa-B kinase subunit betaHomo sapiens (human)IC500.556199
Inhibitor of nuclear factor kappa-B kinase subunit epsilonHomo sapiens (human)IC500.000322
Insulin receptorHomo sapiens (human)IC501.489077
Insulin receptorMus musculus (house mouse)IC500.200011
Insulin receptor-related proteinHomo sapiens (human)IC500.011322
Insulin-like growth factor 1 receptorHomo sapiens (human)IC501.22821414
integrase, partialHuman immunodeficiency virus 1IC504.944022
Interferon-induced, double-stranded RNA-activated protein kinaseHomo sapiens (human)IC500.100011
Interleukin-1 receptor-associated kinase 1Homo sapiens (human)IC500.037722
Interleukin-1 receptor-associated kinase 4Homo sapiens (human)IC500.012244
Interstitial collagenaseHomo sapiens (human)IC5011.360011
Kappa-type opioid receptorHomo sapiens (human)IC5015.629011
Kappa-type opioid receptorHomo sapiens (human)Ki6.252011
Kinase suppressor of Ras 1Homo sapiens (human)IC506.265022
Kinase suppressor of Ras 2Homo sapiens (human)IC505.400022
Kinesin-1 heavy chainHomo sapiens (human)IC500.001511
lens epithelium-derived growth factor p75Homo sapiens (human)IC504.944022
Leucine-rich repeat serine/threonine-protein kinase 2Homo sapiens (human)IC500.007633
Leukocyte tyrosine kinase receptorHomo sapiens (human)IC500.017333
LIM domain kinase 1Homo sapiens (human)IC500.002622
LIM domain kinase 2Homo sapiens (human)IC500.095622
Lymphokine-activated killer T-cell-originated protein kinaseHomo sapiens (human)IC500.069122
Lysine--tRNA ligaseHomo sapiens (human)IC500.004922
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)IC500.1284810
Macrophage-stimulating protein receptorHomo sapiens (human)IC500.219555
Malate dehydrogenaseThermus thermophilusIC5045.000011
MAP kinase-activated protein kinase 2Homo sapiens (human)IC500.73501010
MAP kinase-activated protein kinase 3Homo sapiens (human)IC502.775022
MAP kinase-activated protein kinase 5Homo sapiens (human)IC500.212022
MAP kinase-interacting serine/threonine-protein kinase 1Homo sapiens (human)IC500.053022
MAP kinase-interacting serine/threonine-protein kinase 2Homo sapiens (human)IC500.022133
MAP/microtubule affinity-regulating kinase 3Homo sapiens (human)IC500.000422
MAP/microtubule affinity-regulating kinase 4Homo sapiens (human)IC500.000122
Mast/stem cell growth factor receptor KitHomo sapiens (human)IC500.80941313
Maternal embryonic leucine zipper kinaseHomo sapiens (human)IC500.000622
Megakaryocyte-associated tyrosine-protein kinaseHomo sapiens (human)IC500.442022
Melanocortin receptor 3Homo sapiens (human)IC5019.856011
Melanocortin receptor 3Homo sapiens (human)Ki17.329011
Melanocortin receptor 4Homo sapiens (human)IC5030.481011
Melanocortin receptor 4Homo sapiens (human)Ki29.308011
Melanocortin receptor 5Homo sapiens (human)IC5026.529011
Melanocortin receptor 5Homo sapiens (human)Ki24.886011
Misshapen-like kinase 1Homo sapiens (human)IC500.000444
Mitogen-activated protein kinase 1Homo sapiens (human)IC505.53211111
Mitogen-activated protein kinase 1 Mus musculus (house mouse)IC5010.000011
Mitogen-activated protein kinase 10Homo sapiens (human)IC505.036622
Mitogen-activated protein kinase 11Homo sapiens (human)IC501.000011
Mitogen-activated protein kinase 12Homo sapiens (human)IC500.451233
Mitogen-activated protein kinase 13Homo sapiens (human)IC500.413733
Mitogen-activated protein kinase 14Homo sapiens (human)IC503.670233
Mitogen-activated protein kinase 15Homo sapiens (human)IC500.008133
Mitogen-activated protein kinase 3 Homo sapiens (human)IC509.04751111
Mitogen-activated protein kinase 7Homo sapiens (human)IC505.952444
Mitogen-activated protein kinase 8Homo sapiens (human)IC502.377177
Mitogen-activated protein kinase 9Homo sapiens (human)IC503.644455
Mitogen-activated protein kinase kinase kinase 1Homo sapiens (human)IC500.438022
Mitogen-activated protein kinase kinase kinase 10Homo sapiens (human)IC500.110946
Mitogen-activated protein kinase kinase kinase 11Homo sapiens (human)IC500.021346
Mitogen-activated protein kinase kinase kinase 12Homo sapiens (human)IC500.099222
Mitogen-activated protein kinase kinase kinase 14Homo sapiens (human)IC502.300011
Mitogen-activated protein kinase kinase kinase 19Homo sapiens (human)IC500.008722
Mitogen-activated protein kinase kinase kinase 2Homo sapiens (human)IC500.033522
Mitogen-activated protein kinase kinase kinase 21Homo sapiens (human)IC501.117522
Mitogen-activated protein kinase kinase kinase 3Homo sapiens (human)IC500.009222
Mitogen-activated protein kinase kinase kinase 5Homo sapiens (human)IC500.215055
Mitogen-activated protein kinase kinase kinase 6Homo sapiens (human)IC500.282922
Mitogen-activated protein kinase kinase kinase 7Homo sapiens (human)IC500.056555
Mitogen-activated protein kinase kinase kinase 8Homo sapiens (human)IC509.950011
Mitogen-activated protein kinase kinase kinase 9Homo sapiens (human)IC500.015546
Mitogen-activated protein kinase kinase kinase kinase 1Homo sapiens (human)IC500.052911
Mitogen-activated protein kinase kinase kinase kinase 3Homo sapiens (human)IC500.000122
Mitogen-activated protein kinase kinase kinase kinase 4Homo sapiens (human)IC500.000522
Mitogen-activated protein kinase kinase kinase kinase 5Homo sapiens (human)IC500.000222
MO15-related protein kinase Pfmrk Plasmodium falciparum (malaria parasite P. falciparum)IC504.000022
MPI proteinHomo sapiens (human)IC5030.965011
Mu-type opioid receptorHomo sapiens (human)IC5017.594011
Mu-type opioid receptorHomo sapiens (human)Ki7.142011
Multidrug resistance-associated protein 4Homo sapiens (human)IC5085.450012
Muscarinic acetylcholine receptor M1Homo sapiens (human)IC502.829011
Muscarinic acetylcholine receptor M1Homo sapiens (human)Ki0.681011
Muscarinic acetylcholine receptor M2Homo sapiens (human)IC507.793011
Muscarinic acetylcholine receptor M2Homo sapiens (human)Ki2.771011
Muscarinic acetylcholine receptor M3Homo sapiens (human)IC502.974011
Muscarinic acetylcholine receptor M3Homo sapiens (human)Ki0.630011
Muscarinic acetylcholine receptor M4Homo sapiens (human)IC504.817011
Muscarinic acetylcholine receptor M4Homo sapiens (human)Ki0.672011
Muscarinic acetylcholine receptor M5Homo sapiens (human)IC502.585011
Muscarinic acetylcholine receptor M5Homo sapiens (human)Ki1.857011
Muscle, skeletal receptor tyrosine-protein kinaseHomo sapiens (human)IC500.116133
Myosin light chain kinase 2, skeletal/cardiac muscleHomo sapiens (human)IC500.014722
Myosin light chain kinase 3Homo sapiens (human)IC500.158522
Myosin light chain kinase family member 4Homo sapiens (human)IC500.053722
Myosin light chain kinase, smooth muscleGallus gallus (chicken)IC500.000011
Myosin light chain kinase, smooth muscleHomo sapiens (human)IC500.039144
Myosin light chain kinase, smooth muscleHomo sapiens (human)Ki0.020011
Myosin-IIIaHomo sapiens (human)IC500.042522
Myosin-IIIbHomo sapiens (human)IC500.005822
Myotonin-protein kinaseHomo sapiens (human)IC500.173522
NAD-dependent protein deacetylase HST2Saccharomyces cerevisiae S288CIC50130.000012
NAD-dependent protein deacetylase sirtuin-1Homo sapiens (human)IC504.19171112
NAD-dependent protein deacetylase sirtuin-2Homo sapiens (human)IC5012.022289
NAD-dependent protein deacetylase sirtuin-3, mitochondrialHomo sapiens (human)IC503.700011
NAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)IC5020.600088
NADPH oxidase 4Homo sapiens (human)IC500.070811
Neuraminidase Influenza A virus (A/Wilson-Smith/1933(H1N1))IC5037.666733
Non-receptor tyrosine-protein kinase TNK1Homo sapiens (human)IC500.001222
Non-receptor tyrosine-protein kinase TYK2Homo sapiens (human)IC500.013755
NT-3 growth factor receptorHomo sapiens (human)IC500.000222
NUAK family SNF1-like kinase 1Homo sapiens (human)IC500.003044
NUAK family SNF1-like kinase 2Homo sapiens (human)IC500.001822
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)IC500.967011
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)Ki0.792211
P2X purinoceptor 2Rattus norvegicus (Norway rat)IC5021.905412
P2Y purinoceptor 11Homo sapiens (human)Ki0.207122
P2Y purinoceptor 2Homo sapiens (human)IC5075.000022
P2Y purinoceptor 6Homo sapiens (human)IC5027.000011
PAS domain-containing serine/threonine-protein kinaseHomo sapiens (human)IC500.010722
Peroxisome proliferator-activated receptor alphaHomo sapiens (human)IC500.003116
Peroxisome proliferator-activated receptor gammaHomo sapiens (human)IC500.566011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformHomo sapiens (human)IC5010.000011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformHomo sapiens (human)IC5010.000011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformHomo sapiens (human)IC5010.000011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)IC509.500022
Phospholipase D1Homo sapiens (human)IC5020.000011
Phospholipase D1 Rattus norvegicus (Norway rat)IC5020.000011
Phosphorylase b kinase gamma catalytic chain, liver/testis isoformHomo sapiens (human)IC500.000867
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoformHomo sapiens (human)IC500.001745
Phosphorylase b kinase regulatory subunit alpha, liver isoformHomo sapiens (human)IC500.001323
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoformHomo sapiens (human)IC500.001323
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoformOryctolagus cuniculus (rabbit)IC500.180011
Phosphorylase b kinase regulatory subunit betaHomo sapiens (human)IC500.001323
Platelet-activating factor acetylhydrolaseHomo sapiens (human)IC500.904011
Platelet-derived growth factor receptor alphaHomo sapiens (human)IC500.000788
Platelet-derived growth factor receptor alpha Mus musculus (house mouse)IC500.002011
Platelet-derived growth factor receptor betaHomo sapiens (human)IC501.10421014
Platelet-derived growth factor receptor betaMus musculus (house mouse)IC500.002011
Polyphenol oxidase 2Agaricus bisporusIC50220.000022
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)Ki0.084422
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)IC5030.984033
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)Ki0.792211
Progesterone receptorHomo sapiens (human)IC5050.064422
Prostaglandin G/H synthase 1Homo sapiens (human)IC504.391011
Prostaglandin G/H synthase 1Ovis aries (sheep)IC500.056011
Protein arginine N-methyltransferase 1Homo sapiens (human)IC50344.810033
Protein DBF4 homolog AHomo sapiens (human)IC500.054822
Protein kinase C alpha typeHomo sapiens (human)IC501.44153540
Protein kinase C alpha typeRattus norvegicus (Norway rat)IC504.89221516
Protein kinase C alpha typeHomo sapiens (human)Ki6.000011
Protein kinase C beta typeHomo sapiens (human)IC501.44643440
Protein kinase C beta typeRattus norvegicus (Norway rat)IC504.12121819
Protein kinase C beta typeHomo sapiens (human)Ki6.000011
Protein kinase C beta typeRattus norvegicus (Norway rat)Ki0.019011
Protein kinase C beta type Mus musculus (house mouse)IC500.234011
Protein kinase C delta typeHomo sapiens (human)IC501.95472530
Protein kinase C delta typeRattus norvegicus (Norway rat)IC505.59031314
Protein kinase C delta typeHomo sapiens (human)Ki6.000011
Protein kinase C epsilon typeHomo sapiens (human)IC501.85542631
Protein kinase C epsilon typeRattus norvegicus (Norway rat)IC505.59031314
Protein kinase C epsilon typeHomo sapiens (human)Ki6.000011
Protein kinase C eta typeHomo sapiens (human)IC502.39381924
Protein kinase C eta typeRattus norvegicus (Norway rat)IC505.59031314
Protein kinase C eta typeHomo sapiens (human)Ki6.000011
Protein kinase C gamma typeHomo sapiens (human)IC502.43142224
Protein kinase C gamma typeRattus norvegicus (Norway rat)IC504.37531618
Protein kinase C gamma typeHomo sapiens (human)Ki6.000011
Protein kinase C iota typeHomo sapiens (human)IC504.12971414
Protein kinase C iota typeHomo sapiens (human)Ki6.000011
Protein kinase C theta typeHomo sapiens (human)IC502.15002027
Protein kinase C theta typeRattus norvegicus (Norway rat)IC505.59031314
Protein kinase C theta typeHomo sapiens (human)Ki6.000011
Protein kinase C zeta typeHomo sapiens (human)IC503.65321921
Protein kinase C zeta typeRattus norvegicus (Norway rat)IC505.59031314
Protein kinase C zeta typeHomo sapiens (human)Ki6.000011
Protein odd-skipped-related 1Homo sapiens (human)IC500.040222
Protein-tyrosine kinase 2-betaHomo sapiens (human)IC500.009522
Protein-tyrosine kinase 6Homo sapiens (human)IC500.484044
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)IC500.77121313
Proto-oncogene tyrosine-protein kinase ROSHomo sapiens (human)IC500.000466
Proto-oncogene tyrosine-protein kinase SrcGallus gallus (chicken)IC500.006311
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)IC500.36422525
RAC-alpha serine/threonine-protein kinaseHomo sapiens (human)IC500.53532628
RAC-beta serine/threonine-protein kinaseHomo sapiens (human)IC500.4119810
RAC-gamma serine/threonine-protein kinaseHomo sapiens (human)IC500.3701911
RAF proto-oncogene serine/threonine-protein kinaseHomo sapiens (human)IC502.102555
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)IC501.23551111
Receptor tyrosine-protein kinase erbB-3Homo sapiens (human)IC500.010611
Receptor tyrosine-protein kinase erbB-4Homo sapiens (human)IC500.183088
Receptor-interacting serine/threonine-protein kinase 2Homo sapiens (human)IC500.356022
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)GI500.164333
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)IC500.03993030
Retinoblastoma-associated protein Homo sapiens (human)IC500.066011
Reverse transcriptase/RNaseH Human immunodeficiency virus 1IC5012.200022
Rho-associated protein kinase 1Homo sapiens (human)IC501.431877
Rho-associated protein kinase 2Bos taurus (cattle)IC500.0417211
Rho-associated protein kinase 2Homo sapiens (human)IC502.003655
Rhodopsin kinase GRK1Homo sapiens (human)IC500.068022
Rhodopsin kinase GRK7Homo sapiens (human)IC500.005322
Ribosomal protein S6 kinase alpha-1Homo sapiens (human)IC500.000466
Ribosomal protein S6 kinase alpha-2Homo sapiens (human)IC500.000222
Ribosomal protein S6 kinase alpha-3Homo sapiens (human)IC500.004155
Ribosomal protein S6 kinase alpha-4Homo sapiens (human)IC500.007122
Ribosomal protein S6 kinase alpha-5Homo sapiens (human)IC500.002844
Ribosomal protein S6 kinase alpha-6Homo sapiens (human)IC500.000122
Ribosomal protein S6 kinase beta-1Homo sapiens (human)IC500.003655
Ribosomal protein S6 kinase beta-2Homo sapiens (human)IC500.001522
RmtAAspergillus nidulansIC505.900011
RNA-editing ligase 1, mitochondrialTrypanosoma brucei bruceiIC5051.381011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1Oryctolagus cuniculus (rabbit)IC501.200011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 Homo sapiens (human)IC5027.000011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Mus musculus (house mouse)IC5027.000011
Serine/threonine-protein kinase 10Homo sapiens (human)IC500.038333
Serine/threonine-protein kinase 16Homo sapiens (human)IC500.238522
Serine/threonine-protein kinase 17AHomo sapiens (human)IC500.038633
Serine/threonine-protein kinase 17BHomo sapiens (human)IC500.025811
Serine/threonine-protein kinase 24Homo sapiens (human)IC500.006533
Serine/threonine-protein kinase 25Homo sapiens (human)IC500.002933
Serine/threonine-protein kinase 26Homo sapiens (human)IC500.012422
Serine/threonine-protein kinase 3Homo sapiens (human)IC500.003444
Serine/threonine-protein kinase 32BHomo sapiens (human)IC500.037422
Serine/threonine-protein kinase 32CHomo sapiens (human)IC500.232022
Serine/threonine-protein kinase 33Homo sapiens (human)IC500.037322
Serine/threonine-protein kinase 38Homo sapiens (human)IC500.003722
Serine/threonine-protein kinase 38-likeHomo sapiens (human)IC500.001222
Serine/threonine-protein kinase 4Homo sapiens (human)IC500.001322
Serine/threonine-protein kinase B-rafHomo sapiens (human)IC500.010799
Serine/threonine-protein kinase BRSK1Homo sapiens (human)IC500.000722
Serine/threonine-protein kinase BRSK2Homo sapiens (human)IC500.002822
Serine/threonine-protein kinase Chk1Homo sapiens (human)IC500.17721212
Serine/threonine-protein kinase Chk1Homo sapiens (human)Ki0.007811
Serine/threonine-protein kinase Chk2Homo sapiens (human)IC502.71911010
Serine/threonine-protein kinase D1Homo sapiens (human)IC503.83311515
Serine/threonine-protein kinase D1Homo sapiens (human)Ki6.000011
Serine/threonine-protein kinase D2Homo sapiens (human)IC500.001422
Serine/threonine-protein kinase D3Homo sapiens (human)IC504.10061414
Serine/threonine-protein kinase D3Homo sapiens (human)Ki6.000011
Serine/threonine-protein kinase DCLK1Homo sapiens (human)IC500.267022
Serine/threonine-protein kinase DCLK2Homo sapiens (human)IC500.089022
Serine/threonine-protein kinase haspinHomo sapiens (human)IC500.042233
Serine/threonine-protein kinase ICKHomo sapiens (human)IC500.044333
Serine/threonine-protein kinase LATS1Homo sapiens (human)IC500.013022
Serine/threonine-protein kinase LATS2Homo sapiens (human)IC500.006222
Serine/threonine-protein kinase LMTK3Homo sapiens (human)IC500.026523
Serine/threonine-protein kinase MAKHomo sapiens (human)IC500.025722
Serine/threonine-protein kinase MARK1Homo sapiens (human)IC500.000322
Serine/threonine-protein kinase MARK2Homo sapiens (human)IC500.000122
Serine/threonine-protein kinase MRCK alphaHomo sapiens (human)IC500.003222
Serine/threonine-protein kinase MRCK betaHomo sapiens (human)IC500.002722
Serine/threonine-protein kinase MRCK gammaHomo sapiens (human)IC500.000522
Serine/threonine-protein kinase N1Homo sapiens (human)IC500.002544
Serine/threonine-protein kinase N2Homo sapiens (human)IC500.005544
Serine/threonine-protein kinase N3Homo sapiens (human)IC500.010522
Serine/threonine-protein kinase Nek1Homo sapiens (human)IC500.012233
Serine/threonine-protein kinase Nek11Homo sapiens (human)IC500.521022
Serine/threonine-protein kinase Nek2Homo sapiens (human)IC501.768333
Serine/threonine-protein kinase Nek3Homo sapiens (human)IC5043.950022
Serine/threonine-protein kinase Nek4Homo sapiens (human)IC500.085122
Serine/threonine-protein kinase Nek5Homo sapiens (human)IC500.086422
Serine/threonine-protein kinase Nek6Homo sapiens (human)IC5010.000011
Serine/threonine-protein kinase Nek8Homo sapiens (human)IC500.026322
Serine/threonine-protein kinase Nek9Homo sapiens (human)IC500.101022
Serine/threonine-protein kinase NIM1Homo sapiens (human)IC500.110222
Serine/threonine-protein kinase NLKHomo sapiens (human)IC500.066622
Serine/threonine-protein kinase PAK 1Homo sapiens (human)IC500.000433
Serine/threonine-protein kinase PAK 2Homo sapiens (human)IC502.001655
Serine/threonine-protein kinase PAK 3Homo sapiens (human)IC500.000322
Serine/threonine-protein kinase PAK 4Homo sapiens (human)IC500.013244
Serine/threonine-protein kinase PAK 5Homo sapiens (human)IC500.003922
Serine/threonine-protein kinase PAK 6Homo sapiens (human)IC500.032822
Serine/threonine-protein kinase pim-1Homo sapiens (human)IC500.02971618
Serine/threonine-protein kinase pim-2Homo sapiens (human)IC500.081355
Serine/threonine-protein kinase pim-3Homo sapiens (human)IC500.000133
Serine/threonine-protein kinase PLK1Homo sapiens (human)IC5017.164299
Serine/threonine-protein kinase PLK1Homo sapiens (human)Ki5.643218
Serine/threonine-protein kinase PLK2Homo sapiens (human)IC500.546066
Serine/threonine-protein kinase PLK2Homo sapiens (human)Ki5.643218
Serine/threonine-protein kinase PLK3Homo sapiens (human)IC505.101544
Serine/threonine-protein kinase PLK3Homo sapiens (human)Ki5.643218
Serine/threonine-protein kinase PLK4Homo sapiens (human)IC500.008322
Serine/threonine-protein kinase PLK4Homo sapiens (human)Ki5.016629
Serine/threonine-protein kinase receptor R3Homo sapiens (human)IC500.850011
Serine/threonine-protein kinase SBK1Homo sapiens (human)IC500.146422
Serine/threonine-protein kinase Sgk1Homo sapiens (human)IC500.010033
Serine/threonine-protein kinase Sgk2Homo sapiens (human)IC500.015822
Serine/threonine-protein kinase Sgk3Homo sapiens (human)IC500.073022
Serine/threonine-protein kinase SIK1Homo sapiens (human)IC500.000922
Serine/threonine-protein kinase SIK2Homo sapiens (human)IC500.366933
Serine/threonine-protein kinase SIK3Homo sapiens (human)IC500.154133
Serine/threonine-protein kinase STK11Homo sapiens (human)IC500.059822
Serine/threonine-protein kinase TAO1Homo sapiens (human)IC500.000822
Serine/threonine-protein kinase TAO2Homo sapiens (human)IC500.007622
Serine/threonine-protein kinase TAO3Homo sapiens (human)IC500.001722
Serine/threonine-protein kinase TBK1Homo sapiens (human)IC500.220733
Serine/threonine-protein kinase tousled-like 1Homo sapiens (human)IC500.029533
Serine/threonine-protein kinase tousled-like 2Homo sapiens (human)IC500.003522
Serine/threonine-protein kinase ULK1Homo sapiens (human)IC500.009622
Serine/threonine-protein kinase ULK2Homo sapiens (human)IC500.003222
Serine/threonine-protein kinase ULK3Homo sapiens (human)IC500.002722
Serine/threonine-protein kinase VRK1Homo sapiens (human)IC500.743011
Serine/threonine-protein kinase VRK2Homo sapiens (human)IC5016.400011
Serine/threonine-protein kinase WNK1Homo sapiens (human)IC5014.800022
Serine/threonine-protein kinase WNK2Homo sapiens (human)IC501.455022
Serine/threonine-protein kinase/endoribonuclease IRE1Homo sapiens (human)IC500.124622
Serine/threonine-protein kinase/endoribonuclease IRE2Homo sapiens (human)IC500.041622
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoformHomo sapiens (human)IC5030.573011
Sigma non-opioid intracellular receptor 1Cavia porcellus (domestic guinea pig)IC500.006722
Sigma non-opioid intracellular receptor 1Homo sapiens (human)IC500.021011
Sigma non-opioid intracellular receptor 1Homo sapiens (human)Ki0.021922
Signal transducer and activator of transcription 1-alpha/betaHomo sapiens (human)IC509.100011
Signal transducer and activator of transcription 3 Mus musculus (house mouse)IC50100.000011
Signal transducer and activator of transcription 5AHomo sapiens (human)IC509.400011
Signal transducer and activator of transcription 5BHomo sapiens (human)IC5010.400011
SNF-related serine/threonine-protein kinaseHomo sapiens (human)IC500.005922
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)IC500.028011
Sodium-dependent dopamine transporter Homo sapiens (human)IC501.841011
Sodium-dependent dopamine transporter Homo sapiens (human)Ki1.462011
Sodium-dependent noradrenaline transporter Homo sapiens (human)IC501.472011
Sodium-dependent noradrenaline transporter Homo sapiens (human)Ki1.459011
Sodium-dependent serotonin transporterHomo sapiens (human)IC502.334011
Sodium-dependent serotonin transporterHomo sapiens (human)Ki1.240011
SRSF protein kinase 1Homo sapiens (human)IC500.033622
SRSF protein kinase 2Homo sapiens (human)IC500.206022
SRSF protein kinase 3Homo sapiens (human)IC501.770022
STE20-like serine/threonine-protein kinase Homo sapiens (human)IC500.014233
STE20/SPS1-related proline-alanine-rich protein kinaseHomo sapiens (human)IC500.015822
Steroid hormone receptor ERR1Homo sapiens (human)IC500.200011
Substance-K receptorHomo sapiens (human)IC503.670011
Substance-K receptorHomo sapiens (human)Ki1.223011
Substance-P receptorHomo sapiens (human)IC5015.656011
Substance-P receptorHomo sapiens (human)Ki8.540011
Telomerase reverse transcriptaseHomo sapiens (human)IC506.951766
Testis-specific serine/threonine-protein kinase 1Homo sapiens (human)IC500.000022
Testis-specific serine/threonine-protein kinase 1Mus musculus (house mouse)IC500.000311
Testis-specific serine/threonine-protein kinase 2Homo sapiens (human)IC500.003822
Testis-specific serine/threonine-protein kinase 3Homo sapiens (human)IC500.005122
Testis-specific serine/threonine-protein kinase 6Homo sapiens (human)IC500.152522
TGF-beta receptor type-1Homo sapiens (human)IC505.793137
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1Homo sapiens (human)IC500.037022
Thioredoxin reductase 1, cytoplasmicHomo sapiens (human)IC500.043211
Thromboxane-A synthase Homo sapiens (human)IC500.916011
TRAF2 and NCK-interacting protein kinaseHomo sapiens (human)IC500.010344
Transcriptional activator protein LuxRAliivibrio fischeriIC5040.000011
Tyrosine-protein kinase ABL1Homo sapiens (human)GI5020.000011
Tyrosine-protein kinase ABL1Homo sapiens (human)IC500.31011717
Tyrosine-protein kinase ABL2Homo sapiens (human)IC500.050444
Tyrosine-protein kinase BlkHomo sapiens (human)IC500.001122
Tyrosine-protein kinase BTKHomo sapiens (human)IC503.146688
Tyrosine-protein kinase CSKHomo sapiens (human)IC500.207133
Tyrosine-protein kinase FerHomo sapiens (human)IC500.000833
Tyrosine-protein kinase Fes/FpsHomo sapiens (human)IC500.003933
Tyrosine-protein kinase FgrHomo sapiens (human)IC500.000922
Tyrosine-protein kinase FRKHomo sapiens (human)IC500.010822
Tyrosine-protein kinase FynHomo sapiens (human)IC500.63531212
Tyrosine-protein kinase HCKHomo sapiens (human)IC503.335033
Tyrosine-protein kinase ITK/TSKHomo sapiens (human)IC505.337933
Tyrosine-protein kinase ITK/TSKHomo sapiens (human)Ki0.006112
Tyrosine-protein kinase JAK1Homo sapiens (human)IC501.220066
Tyrosine-protein kinase JAK2Homo sapiens (human)IC501.00141010
Tyrosine-protein kinase JAK3Homo sapiens (human)IC500.10161616
Tyrosine-protein kinase LckHomo sapiens (human)IC501.44101414
Tyrosine-protein kinase LynHomo sapiens (human)IC500.00121212
Tyrosine-protein kinase MerHomo sapiens (human)IC500.033133
Tyrosine-protein kinase receptor TYRO3Homo sapiens (human)IC500.017733
Tyrosine-protein kinase receptor UFOHomo sapiens (human)IC501.527666
Tyrosine-protein kinase SrmsHomo sapiens (human)IC506.500022
Tyrosine-protein kinase SYKHomo sapiens (human)IC500.71951414
Tyrosine-protein kinase TecHomo sapiens (human)IC5042.689233
Tyrosine-protein kinase TXKHomo sapiens (human)IC500.020422
Tyrosine-protein kinase YesHomo sapiens (human)IC500.002944
Tyrosine-protein kinase ZAP-70Homo sapiens (human)IC501.126799
Tyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)IC509.760011
ubiquitin-conjugating enzyme E2 NHomo sapiens (human)IC5020.000011
Uracil nucleotide/cysteinyl leukotriene receptorHomo sapiens (human)IC50100.000011
Vascular endothelial growth factor receptor 1 Homo sapiens (human)IC500.014977
Vascular endothelial growth factor receptor 2Homo sapiens (human)IC500.99913640
Vascular endothelial growth factor receptor 2Homo sapiens (human)Ki0.001711
Vascular endothelial growth factor receptor 3Homo sapiens (human)IC500.47321010
Xanthine dehydrogenase/oxidaseBos taurus (cattle)IC5021.730011

Activation Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
26S proteasome regulatory subunit 6BHomo sapiens (human)Kd30.000014
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)Kd0.001011
3-phosphoinositide-dependent protein kinase 1Homo sapiens (human)Kd0.098735
5'-AMP-activated protein kinase catalytic subunit alpha-1Homo sapiens (human)Kd4.873459
5'-AMP-activated protein kinase catalytic subunit alpha-2Homo sapiens (human)Kd0.280835
5'-AMP-activated protein kinase subunit gamma-1Homo sapiens (human)Kd10.506713
5'-AMP-activated protein kinase subunit gamma-2Homo sapiens (human)Kd13.332013
7-dehydrocholesterol reductaseHomo sapiens (human)Kd0.001011
AarF domain-containing protein kinase 1Homo sapiens (human)Kd22.030013
Actin-related protein 2Homo sapiens (human)Kd30.000013
Actin-related protein 3Homo sapiens (human)Kd30.000014
Activated CDC42 kinase 1Homo sapiens (human)Kd4.038648
Activin receptor type-1Homo sapiens (human)Kd15.117548
Activin receptor type-1BHomo sapiens (human)Kd13.327248
Activin receptor type-2AHomo sapiens (human)Kd9.780035
Activin receptor type-2BHomo sapiens (human)Kd16.150048
Acyl-CoA dehydrogenase family member 10Homo sapiens (human)Kd30.000012
Acyl-CoA dehydrogenase family member 11Homo sapiens (human)Kd30.000011
Adenosine kinaseHomo sapiens (human)Kd30.000013
Adenylate kinase 2, mitochondrialHomo sapiens (human)Kd30.000013
ADP/ATP translocase 2Homo sapiens (human)Kd30.000013
ADP/ATP translocase 3Homo sapiens (human)Kd30.000013
ALK tyrosine kinase receptorHomo sapiens (human)Kd8.696347
Alpha-tocopherol transfer proteinHomo sapiens (human)Kd2.420011
Angiopoietin-1 receptorHomo sapiens (human)Kd1.036746
Angiotensin-converting enzyme 2 Homo sapiens (human)EC5037.563313
Ankyrin repeat and protein kinase domain-containing protein 1Homo sapiens (human)Kd6.108035
AP2-associated protein kinase 1Homo sapiens (human)Kd3.396259
ATP-dependent 6-phosphofructokinase, platelet typeHomo sapiens (human)Kd30.000013
ATP-dependent RNA helicase DDX1Homo sapiens (human)Kd30.000013
ATP-dependent RNA helicase DDX3XHomo sapiens (human)Kd30.000013
ATP-dependent RNA helicase DDX42Homo sapiens (human)Kd30.000011
ATP-dependent RNA helicase DHX30Homo sapiens (human)Kd30.000011
ATP-dependent translocase ABCB1Homo sapiens (human)EC5056.500011
Atypical kinase COQ8A, mitochondrialHomo sapiens (human)Kd20.0000410
Atypical kinase COQ8B, mitochondrialHomo sapiens (human)Kd10.000035
Aurora kinase AHomo sapiens (human)Kd3.1019610
Aurora kinase BHomo sapiens (human)Kd4.123248
Aurora kinase CHomo sapiens (human)Kd0.094546
BDNF/NT-3 growth factors receptorHomo sapiens (human)Kd0.187535
Beta-adrenergic receptor kinase 1Homo sapiens (human)Kd30.000013
BMP-2-inducible protein kinaseHomo sapiens (human)Kd3.477059
Bone morphogenetic protein receptor type-1AHomo sapiens (human)Kd15.925048
Bone morphogenetic protein receptor type-1BHomo sapiens (human)Kd18.361736
Bone morphogenetic protein receptor type-2Homo sapiens (human)Kd16.537548
Breakpoint cluster region proteinHomo sapiens (human)Kd30.000013
Calcium-dependent protein kinase 1Plasmodium falciparum 3D7Kd0.475112
Calcium/calmodulin-dependent protein kinase kinase 1Homo sapiens (human)Kd0.065046
Calcium/calmodulin-dependent protein kinase kinase 2Homo sapiens (human)Kd6.6112510
Calcium/calmodulin-dependent protein kinase type 1Homo sapiens (human)Kd1.014046
Calcium/calmodulin-dependent protein kinase type 1DHomo sapiens (human)Kd0.335746
Calcium/calmodulin-dependent protein kinase type 1GHomo sapiens (human)Kd0.739835
Calcium/calmodulin-dependent protein kinase type II subunit alphaHomo sapiens (human)Kd0.010146
Calcium/calmodulin-dependent protein kinase type II subunit betaHomo sapiens (human)Kd0.105946
Calcium/calmodulin-dependent protein kinase type II subunit deltaHomo sapiens (human)Kd3.431959
Calcium/calmodulin-dependent protein kinase type II subunit gammaHomo sapiens (human)Kd3.2775610
Calcium/calmodulin-dependent protein kinase type IVHomo sapiens (human)Kd15.010248
cAMP-dependent protein kinase catalytic subunit alphaHomo sapiens (human)Kd13.068337
cAMP-dependent protein kinase catalytic subunit betaHomo sapiens (human)Kd11.347248
cAMP-dependent protein kinase catalytic subunit gammaHomo sapiens (human)Kd30.000013
cAMP-dependent protein kinase catalytic subunit PRKXHomo sapiens (human)Kd0.581235
cAMP-dependent protein kinase type II-alpha regulatory subunitHomo sapiens (human)Kd30.000013
Casein kinase I isoform alphaHomo sapiens (human)Kd18.495036
Casein kinase I isoform alpha-likeHomo sapiens (human)Kd5.125024
Casein kinase I isoform deltaHomo sapiens (human)Kd15.600048
Casein kinase I isoform epsilonHomo sapiens (human)Kd15.0836510
Casein kinase I isoform gamma-1Homo sapiens (human)Kd16.687548
Casein kinase I isoform gamma-2Homo sapiens (human)Kd11.620058
Casein kinase I isoform gamma-3Homo sapiens (human)Kd17.500048
Casein kinase II subunit alphaHomo sapiens (human)Kd2.295235
Casein kinase II subunit alpha'Homo sapiens (human)Kd15.029648
Cell division control protein 2 homologPlasmodium falciparum 3D7Kd5.400012
Cell division cycle 7-related protein kinaseHomo sapiens (human)Kd30.000011
cGMP-dependent protein kinase 1 Homo sapiens (human)Kd11.351748
cGMP-dependent protein kinase 2Homo sapiens (human)Kd0.050835
Chain A, Hepatocyte growth factor receptorHomo sapiens (human)Kd0.010011
Chromodomain-helicase-DNA-binding protein 4Homo sapiens (human)Kd30.000012
Citron Rho-interacting kinaseHomo sapiens (human)Kd15.085048
Cyclin-dependent kinase 1Homo sapiens (human)Kd30.000013
Cyclin-dependent kinase 10Homo sapiens (human)Kd30.000012
Cyclin-dependent kinase 11AHomo sapiens (human)Kd10.000035
Cyclin-dependent kinase 11BHomo sapiens (human)Kd10.000035
Cyclin-dependent kinase 12Homo sapiens (human)Kd30.000014
Cyclin-dependent kinase 13Homo sapiens (human)Kd20.014025
Cyclin-dependent kinase 14Homo sapiens (human)Kd6.064035
Cyclin-dependent kinase 15Homo sapiens (human)Kd6.753323
Cyclin-dependent kinase 16Homo sapiens (human)Kd13.341459
Cyclin-dependent kinase 17Homo sapiens (human)Kd12.884647
Cyclin-dependent kinase 18Homo sapiens (human)Kd6.108035
Cyclin-dependent kinase 19Homo sapiens (human)Kd4.396035
Cyclin-dependent kinase 2Homo sapiens (human)Kd10.013759
Cyclin-dependent kinase 3Homo sapiens (human)Kd11.261548
Cyclin-dependent kinase 4Homo sapiens (human)Kd13.760538
Cyclin-dependent kinase 6Homo sapiens (human)Kd20.133013
Cyclin-dependent kinase 7Homo sapiens (human)Kd15.011248
Cyclin-dependent kinase 8Homo sapiens (human)Kd6.204035
Cyclin-dependent kinase 9Homo sapiens (human)Kd15.025048
Cyclin-dependent kinase-like 1Homo sapiens (human)Kd5.165012
Cyclin-dependent kinase-like 2Homo sapiens (human)Kd6.836723
Cyclin-dependent kinase-like 3Homo sapiens (human)Kd8.366723
Cyclin-dependent kinase-like 5Homo sapiens (human)Kd18.390036
Cyclin-dependent-like kinase 5 Homo sapiens (human)Kd10.129859
Cyclin-G-associated kinaseHomo sapiens (human)Kd6.945759
Cysteine--tRNA ligase, cytoplasmicHomo sapiens (human)Kd30.000011
Cytochrome c1, heme protein, mitochondrialHomo sapiens (human)Kd30.000013
Cytoplasmic tyrosine-protein kinase BMXHomo sapiens (human)Kd5.125046
dCTP pyrophosphatase 1Homo sapiens (human)Kd30.000013
Death-associated protein kinase 1Homo sapiens (human)Kd2.820635
Death-associated protein kinase 2Homo sapiens (human)Kd0.446046
Death-associated protein kinase 3Homo sapiens (human)Kd2.112958
Delta-type opioid receptorHomo sapiens (human)EC50100.000011
Delta(24)-sterol reductaseHomo sapiens (human)Kd30.000013
Deoxycytidine kinaseHomo sapiens (human)Kd30.000013
Discoidin domain-containing receptor 2Homo sapiens (human)Kd15.010548
DNA replication licensing factor MCM4Homo sapiens (human)Kd30.000013
DNA topoisomerase 2-alphaHomo sapiens (human)Kd30.000013
DNA topoisomerase 2-betaHomo sapiens (human)Kd30.000013
DnaJ homolog subfamily A member 1Homo sapiens (human)Kd30.000013
Dual serine/threonine and tyrosine protein kinaseHomo sapiens (human)Kd2.355512
Dual specificity mitogen-activated protein kinase kinase 1Homo sapiens (human)Kd11.473648
Dual specificity mitogen-activated protein kinase kinase 2Homo sapiens (human)Kd11.316248
Dual specificity mitogen-activated protein kinase kinase 3Homo sapiens (human)Kd13.238848
Dual specificity mitogen-activated protein kinase kinase 4Homo sapiens (human)Kd7.423346
Dual specificity mitogen-activated protein kinase kinase 5Homo sapiens (human)Kd14.407225
Dual specificity mitogen-activated protein kinase kinase 6Homo sapiens (human)Kd12.955049
Dual specificity mitogen-activated protein kinase kinase 7Homo sapiens (human)Kd5.015012
Dual specificity protein kinase CLK1Homo sapiens (human)Kd6.794659
Dual specificity protein kinase CLK2Homo sapiens (human)Kd4.059859
Dual specificity protein kinase CLK3Homo sapiens (human)Kd8.417157
Dual specificity protein kinase CLK4Homo sapiens (human)Kd6.808859
Dual specificity protein kinase TTKHomo sapiens (human)Kd3.912858
Dual specificity testis-specific protein kinase 1Homo sapiens (human)Kd15.080048
Dual specificity testis-specific protein kinase 2Homo sapiens (human)Kd30.000011
Dual specificity tyrosine-phosphorylation-regulated kinase 1AHomo sapiens (human)Kd10.842736
Dual specificity tyrosine-phosphorylation-regulated kinase 1BHomo sapiens (human)Kd5.174346
Dual specificity tyrosine-phosphorylation-regulated kinase 2Homo sapiens (human)Kd6.750023
Dynamin-like 120 kDa protein, mitochondrialHomo sapiens (human)Kd30.000013
eIF-2-alpha kinase GCN2Homo sapiens (human)Kd0.029835
EKC/KEOPS complex subunit TP53RKHomo sapiens (human)Kd21.280013
Electron transfer flavoprotein subunit betaHomo sapiens (human)Kd30.000012
Elongation factor Tu, mitochondrialHomo sapiens (human)Kd30.000014
Ephrin type-A receptor 1Homo sapiens (human)Kd15.075048
Ephrin type-A receptor 2Homo sapiens (human)Kd16.6609511
Ephrin type-A receptor 3Homo sapiens (human)Kd5.018246
Ephrin type-A receptor 4Homo sapiens (human)Kd13.476759
Ephrin type-A receptor 5Homo sapiens (human)Kd15.0340510
Ephrin type-A receptor 6Homo sapiens (human)Kd5.136746
Ephrin type-A receptor 7Homo sapiens (human)Kd13.550059
Ephrin type-A receptor 8Homo sapiens (human)Kd5.113346
Ephrin type-B receptor 1Homo sapiens (human)Kd5.178346
Ephrin type-B receptor 2Homo sapiens (human)Kd15.525048
Ephrin type-B receptor 3Homo sapiens (human)Kd18.888949
Ephrin type-B receptor 4Homo sapiens (human)Kd16.525048
Ephrin type-B receptor 6Homo sapiens (human)Kd18.058637
Epidermal growth factor receptorHomo sapiens (human)Kd2.96383054
Epithelial discoidin domain-containing receptor 1Homo sapiens (human)Kd13.954848
Estrogen receptorHomo sapiens (human)EC501.156835
Estrogen receptorRattus norvegicus (Norway rat)EC50150.000012
Estrogen receptor betaHomo sapiens (human)EC500.980835
Estrogen receptor betaRattus norvegicus (Norway rat)EC50150.000012
Eukaryotic translation initiation factor 2-alpha kinase 1Homo sapiens (human)Kd18.674526
Eukaryotic translation initiation factor 5BHomo sapiens (human)Kd30.000013
Exosome RNA helicase MTR4Homo sapiens (human)Kd30.000013
Ferrochelatase, mitochondrialHomo sapiens (human)Kd30.000014
Fibroblast growth factor receptor 1Homo sapiens (human)Kd10.560059
Fibroblast growth factor receptor 2Homo sapiens (human)Kd1.260046
Fibroblast growth factor receptor 3Homo sapiens (human)Kd3.2733711
Fibroblast growth factor receptor 4Homo sapiens (human)Kd6.100035
Focal adhesion kinase 1Homo sapiens (human)Kd13.355159
G protein-coupled receptor kinase 4Homo sapiens (human)Kd0.085723
G protein-coupled receptor kinase 6Homo sapiens (human)Kd30.000011
General transcription and DNA repair factor IIH helicase subunit XPDHomo sapiens (human)Kd30.000013
Glycine--tRNA ligaseHomo sapiens (human)Kd30.000013
Glycogen phosphorylase, brain formHomo sapiens (human)Kd30.000013
Glycogen phosphorylase, liver formHomo sapiens (human)Kd30.000013
Glycogen synthase kinase-3 alphaHomo sapiens (human)Kd8.622648
Glycogen synthase kinase-3 betaHomo sapiens (human)Kd8.280948
glycogen synthase kinase-3 beta isoform 1Homo sapiens (human)EC50300.000012
GTP-binding nuclear protein RanHomo sapiens (human)Kd30.000013
Guanine nucleotide-binding protein G(i) subunit alpha-2Homo sapiens (human)Kd30.000012
Heme oxygenase 2Homo sapiens (human)Kd30.000014
Hepatocyte growth factor receptorHomo sapiens (human)Kd7.0029814
High affinity nerve growth factor receptorHomo sapiens (human)Kd6.987759
Homeodomain-interacting protein kinase 1Homo sapiens (human)Kd7.566723
Homeodomain-interacting protein kinase 2Homo sapiens (human)Kd2.130023
Homeodomain-interacting protein kinase 3Homo sapiens (human)Kd1.558323
Homeodomain-interacting protein kinase 4Homo sapiens (human)Kd0.763323
Hormonally up-regulated neu tumor-associated kinaseHomo sapiens (human)Kd0.366723
Inhibitor of nuclear factor kappa-B kinase subunit alphaHomo sapiens (human)Kd2.535323
Inhibitor of nuclear factor kappa-B kinase subunit betaHomo sapiens (human)Kd5.443723
Inhibitor of nuclear factor kappa-B kinase subunit epsilonHomo sapiens (human)Kd3.928448
Inosine-5'-monophosphate dehydrogenase 2Homo sapiens (human)Kd30.000011
Insulin receptorHomo sapiens (human)Kd13.365959
Insulin receptor-related proteinHomo sapiens (human)Kd6.032435
Insulin-like growth factor 1 receptorHomo sapiens (human)Kd15.052548
Integrin-linked protein kinaseHomo sapiens (human)Kd30.000012
Interferon-induced, double-stranded RNA-activated protein kinaseHomo sapiens (human)Kd4.284035
Interleukin-1 receptor-associated kinase 1Homo sapiens (human)Kd18.340036
Interleukin-1 receptor-associated kinase 3Homo sapiens (human)Kd4.322448
Interleukin-1 receptor-associated kinase 4Homo sapiens (human)Kd14.002125
Isoleucine--tRNA ligase, mitochondrialHomo sapiens (human)Kd30.000011
Kappa-type opioid receptorHomo sapiens (human)EC50100.000011
Leucine-rich repeat serine/threonine-protein kinase 2Homo sapiens (human)Kd0.188424
Leukocyte tyrosine kinase receptorHomo sapiens (human)Kd1.814835
Leukotriene C4 synthaseCavia porcellus (domestic guinea pig)Kd6.750012
LIM domain kinase 1Homo sapiens (human)Kd15.1650510
LIM domain kinase 2Homo sapiens (human)Kd18.711149
Long-chain-fatty-acid--CoA ligase 5Homo sapiens (human)Kd30.000012
Lysosomal acid glucosylceramidaseHomo sapiens (human)EC502.500011
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)Kd0.202835
Macrophage-stimulating protein receptorHomo sapiens (human)Kd18.400036
MAP kinase-activated protein kinase 2Homo sapiens (human)Kd15.220048
MAP kinase-activated protein kinase 3Homo sapiens (human)Kd30.000011
MAP kinase-activated protein kinase 5Homo sapiens (human)Kd16.283748
MAP kinase-interacting serine/threonine-protein kinase 1Homo sapiens (human)Kd6.068035
MAP kinase-interacting serine/threonine-protein kinase 2Homo sapiens (human)Kd0.484346
MAP/microtubule affinity-regulating kinase 3Homo sapiens (human)Kd3.942948
MAP/microtubule affinity-regulating kinase 4Homo sapiens (human)Kd10.127649
Mast/stem cell growth factor receptor KitHomo sapiens (human)Kd0.19482237
Maternal embryonic leucine zipper kinaseHomo sapiens (human)Kd7.623648
Megakaryocyte-associated tyrosine-protein kinaseHomo sapiens (human)Kd6.753323
Membrane-associated progesterone receptor component 1Homo sapiens (human)Kd30.000011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinaseHomo sapiens (human)Kd17.500048
Microtubule-associated serine/threonine-protein kinase 1Homo sapiens (human)Kd3.446723
MidasinHomo sapiens (human)Kd30.000014
Misshapen-like kinase 1Homo sapiens (human)Kd6.076435
Mitogen-activated protein kinase 1Homo sapiens (human)Kd16.825048
Mitogen-activated protein kinase 10Homo sapiens (human)Kd11.262259
Mitogen-activated protein kinase 11Homo sapiens (human)Kd17.500048
Mitogen-activated protein kinase 12Homo sapiens (human)Kd5.029346
Mitogen-activated protein kinase 13Homo sapiens (human)Kd6.746723
Mitogen-activated protein kinase 14Homo sapiens (human)Kd17.500048
Mitogen-activated protein kinase 15Homo sapiens (human)Kd11.279648
Mitogen-activated protein kinase 3 Homo sapiens (human)Kd17.100048
Mitogen-activated protein kinase 4Homo sapiens (human)Kd10.000035
Mitogen-activated protein kinase 6Homo sapiens (human)Kd8.620035
Mitogen-activated protein kinase 7Homo sapiens (human)Kd15.400048
Mitogen-activated protein kinase 8Homo sapiens (human)Kd8.301259
Mitogen-activated protein kinase 9Homo sapiens (human)Kd10.888459
Mitogen-activated protein kinase kinase kinase 1Homo sapiens (human)Kd18.391736
Mitogen-activated protein kinase kinase kinase 10Homo sapiens (human)Kd2.336835
Mitogen-activated protein kinase kinase kinase 11Homo sapiens (human)Kd3.2272510
Mitogen-activated protein kinase kinase kinase 12Homo sapiens (human)Kd5.750012
Mitogen-activated protein kinase kinase kinase 13Homo sapiens (human)Kd1.936723
Mitogen-activated protein kinase kinase kinase 15Homo sapiens (human)Kd6.667523
Mitogen-activated protein kinase kinase kinase 19Homo sapiens (human)Kd0.010323
Mitogen-activated protein kinase kinase kinase 2Homo sapiens (human)Kd10.733436
Mitogen-activated protein kinase kinase kinase 20Homo sapiens (human)Kd17.500048
Mitogen-activated protein kinase kinase kinase 3Homo sapiens (human)Kd15.536736
Mitogen-activated protein kinase kinase kinase 4Homo sapiens (human)Kd16.7818511
Mitogen-activated protein kinase kinase kinase 5Homo sapiens (human)Kd9.0632610
Mitogen-activated protein kinase kinase kinase 6Homo sapiens (human)Kd13.432536
Mitogen-activated protein kinase kinase kinase 7Homo sapiens (human)Kd0.109023
Mitogen-activated protein kinase kinase kinase 9Homo sapiens (human)Kd0.013035
Mitogen-activated protein kinase kinase kinase kinase 1Homo sapiens (human)Kd8.345148
Mitogen-activated protein kinase kinase kinase kinase 2Homo sapiens (human)Kd10.856636
Mitogen-activated protein kinase kinase kinase kinase 3Homo sapiens (human)Kd7.843848
Mitogen-activated protein kinase kinase kinase kinase 4Homo sapiens (human)Kd4.199648
Mitogen-activated protein kinase kinase kinase kinase 5Homo sapiens (human)Kd7.061759
Mitotic checkpoint serine/threonine-protein kinase BUB1Homo sapiens (human)Kd30.000013
Mu-type opioid receptorHomo sapiens (human)EC50100.000011
Multifunctional protein ADE2Homo sapiens (human)Kd30.000013
Muscle, skeletal receptor tyrosine-protein kinaseHomo sapiens (human)Kd6.034435
Myosin light chain kinase 2, skeletal/cardiac muscleHomo sapiens (human)Kd5.038746
Myosin light chain kinase 3Homo sapiens (human)Kd12.507625
Myosin light chain kinase family member 4Homo sapiens (human)Kd0.572035
Myosin light chain kinase, smooth muscleGallus gallus (chicken)Kd5.070012
Myosin light chain kinase, smooth muscleHomo sapiens (human)Kd11.583359
Myosin-14Homo sapiens (human)Kd30.000013
Myosin-IIIaHomo sapiens (human)Kd6.200035
Myosin-IIIbHomo sapiens (human)Kd6.120035
Myotonin-protein kinaseHomo sapiens (human)Kd2.281435
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13Homo sapiens (human)Kd30.000013
Non-receptor tyrosine-protein kinase TNK1Homo sapiens (human)Kd3.925548
Non-receptor tyrosine-protein kinase TYK2Homo sapiens (human)Kd10.3602611
NT-3 growth factor receptorHomo sapiens (human)Kd1.026835
NUAK family SNF1-like kinase 1Homo sapiens (human)Kd0.026435
NUAK family SNF1-like kinase 2Homo sapiens (human)Kd11.273648
Nuclear receptor subfamily 1 group I member 2Homo sapiens (human)EC501.300011
Nucleolar GTP-binding protein 1Homo sapiens (human)Kd19.099012
Obg-like ATPase 1Homo sapiens (human)Kd30.000011
P2X purinoceptor 1Rattus norvegicus (Norway rat)EC501.000011
P2X purinoceptor 2Rattus norvegicus (Norway rat)EC5010.400011
P2X purinoceptor 3Homo sapiens (human)EC508.950022
P2X purinoceptor 4Rattus norvegicus (Norway rat)EC50100.000011
P2X purinoceptor 5Rattus norvegicus (Norway rat)EC504.000011
P2X purinoceptor 6Rattus norvegicus (Norway rat)EC50100.000011
P2X purinoceptor 7Homo sapiens (human)EC5092.000011
P2Y purinoceptor 1Meleagris gallopavo (turkey)EC5010.000011
P2Y purinoceptor 11Homo sapiens (human)EC5016.000011
P2Y purinoceptor 12Rattus norvegicus (Norway rat)EC504.000011
P2Y purinoceptor 2Homo sapiens (human)EC5048.000011
P2Y purinoceptor 4Homo sapiens (human)EC50100.000011
PAS domain-containing serine/threonine-protein kinaseHomo sapiens (human)Kd30.000011
Peripheral plasma membrane protein CASKHomo sapiens (human)Kd5.009512
Peroxisomal acyl-coenzyme A oxidase 1Homo sapiens (human)Kd30.000011
Peroxisomal acyl-coenzyme A oxidase 3Homo sapiens (human)Kd30.000013
Phenylalanine--tRNA ligase beta subunitHomo sapiens (human)Kd30.000013
Phosphatidylethanolamine-binding protein 1Homo sapiens (human)Kd30.000011
Phosphatidylinositol 4-kinase betaHomo sapiens (human)Kd6.820023
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit betaHomo sapiens (human)Kd7.133323
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gammaHomo sapiens (human)Kd0.523323
Phosphatidylinositol 4-phosphate 5-kinase type-1 alphaHomo sapiens (human)Kd0.203235
Phosphatidylinositol 4-phosphate 5-kinase type-1 gammaHomo sapiens (human)Kd6.350012
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformHomo sapiens (human)Kd9.16972133
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformHomo sapiens (human)Kd10.000023
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformHomo sapiens (human)Kd10.000023
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)Kd7.266723
Phosphatidylinositol 5-phosphate 4-kinase type-2 alphaHomo sapiens (human)Kd30.000011
Phosphatidylinositol 5-phosphate 4-kinase type-2 betaHomo sapiens (human)Kd0.192835
Phosphatidylinositol 5-phosphate 4-kinase type-2 gammaHomo sapiens (human)Kd22.000025
Phosphorylase b kinase gamma catalytic chain, liver/testis isoformHomo sapiens (human)Kd7.440559
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoformHomo sapiens (human)Kd0.332046
Platelet-derived growth factor receptor alphaHomo sapiens (human)Kd0.192035
Platelet-derived growth factor receptor betaHomo sapiens (human)Kd6.845859
Poly [ADP-ribose] polymerase tankyrase-2Homo sapiens (human)Kd0.120011
POsterior SegregationCaenorhabditis elegansEC5015.805011
Probable ATP-dependent RNA helicase DDX6Homo sapiens (human)Kd30.000013
Procathepsin LHomo sapiens (human)EC5037.563313
Prostaglandin G/H synthase 2Homo sapiens (human)Kd0.665012
Protein delta homolog 1Homo sapiens (human)Kd10.000011
Protein kinase C alpha typeHomo sapiens (human)Kd6.612635
Protein kinase C beta typeHomo sapiens (human)Kd20.008013
Protein kinase C delta typeHomo sapiens (human)Kd10.107649
Protein kinase C epsilon typeHomo sapiens (human)Kd0.324135
Protein kinase C eta typeHomo sapiens (human)Kd0.175935
Protein kinase C iota typeHomo sapiens (human)Kd20.005225
Protein kinase C theta typeHomo sapiens (human)Kd7.848848
Protein kinase C zeta typeHomo sapiens (human)Kd30.000011
Protein-tyrosine kinase 2-betaHomo sapiens (human)Kd7.918448
Protein-tyrosine kinase 6Homo sapiens (human)Kd17.177849
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)Kd2.74411119
Proto-oncogene tyrosine-protein kinase ROSHomo sapiens (human)Kd0.270035
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)Kd9.3880610
Putative heat shock protein HSP 90-beta 2Homo sapiens (human)Kd30.000014
Pyridoxal kinaseHomo sapiens (human)Kd30.000013
Rab-like protein 3Homo sapiens (human)Kd30.000013
RAC-alpha serine/threonine-protein kinaseHomo sapiens (human)EC500.460022
RAC-alpha serine/threonine-protein kinaseHomo sapiens (human)Kd11.611248
RAC-beta serine/threonine-protein kinaseHomo sapiens (human)Kd11.553548
RAC-gamma serine/threonine-protein kinaseHomo sapiens (human)Kd14.342548
RAF proto-oncogene serine/threonine-protein kinaseHomo sapiens (human)Kd10.000035
Ras-related C3 botulinum toxin substrate 1Homo sapiens (human)Kd30.000011
Ras-related protein Rab-10Homo sapiens (human)Kd30.000013
Ras-related protein Rab-27AHomo sapiens (human)Kd30.000013
Ras-related protein Rab-6AHomo sapiens (human)Kd30.000014
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)Kd8.038035
Receptor tyrosine-protein kinase erbB-3Homo sapiens (human)Kd10.000023
Receptor tyrosine-protein kinase erbB-4Homo sapiens (human)Kd2.323323
Receptor-interacting serine/threonine-protein kinase 1Homo sapiens (human)Kd10.000035
Receptor-interacting serine/threonine-protein kinase 2Homo sapiens (human)Kd11.780759
Receptor-interacting serine/threonine-protein kinase 3Homo sapiens (human)Kd30.000013
Receptor-interacting serine/threonine-protein kinase 4Homo sapiens (human)Kd6.703323
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)Kd0.77042540
Replicase polyprotein 1aSevere acute respiratory syndrome-related coronavirusEC5037.563313
Replicase polyprotein 1abBetacoronavirus England 1EC5037.563313
Replicase polyprotein 1abHuman coronavirus 229EEC5037.563313
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2EC5037.563313
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirusEC5037.563313
Rho-associated protein kinase 1Homo sapiens (human)Kd17.600036
Rho-associated protein kinase 2Homo sapiens (human)Kd15.766736
Rhodopsin kinase GRK1Homo sapiens (human)Kd0.057023
Rhodopsin kinase GRK7Homo sapiens (human)Kd0.032323
Ribosomal protein S6 kinase alpha-1Homo sapiens (human)Kd6.7585713
Ribosomal protein S6 kinase alpha-2Homo sapiens (human)Kd2.9189711
Ribosomal protein S6 kinase alpha-3Homo sapiens (human)Kd5.351759
Ribosomal protein S6 kinase alpha-4Homo sapiens (human)Kd7.4063713
Ribosomal protein S6 kinase alpha-5Homo sapiens (human)Kd7.6966814
Ribosomal protein S6 kinase alpha-6Homo sapiens (human)Kd3.4852713
Ribosomal protein S6 kinase beta-1Homo sapiens (human)Kd16.883636
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)Kd21.343713
RNA cytidine acetyltransferaseHomo sapiens (human)Kd30.000013
S-adenosylmethionine synthase isoform type-2Homo sapiens (human)Kd30.000013
Septin-9Homo sapiens (human)Kd30.000013
Serine/threonine-protein kinase 10Homo sapiens (human)Kd6.916859
Serine/threonine-protein kinase 16Homo sapiens (human)Kd10.175659
Serine/threonine-protein kinase 17AHomo sapiens (human)Kd0.958546
Serine/threonine-protein kinase 17BHomo sapiens (human)Kd2.361346
Serine/threonine-protein kinase 24Homo sapiens (human)Kd12.891447
Serine/threonine-protein kinase 25Homo sapiens (human)Kd1.124035
Serine/threonine-protein kinase 26Homo sapiens (human)Kd15.035048
Serine/threonine-protein kinase 3Homo sapiens (human)Kd7.565448
Serine/threonine-protein kinase 3Mus musculus (house mouse)Kd0.000111
Serine/threonine-protein kinase 32AHomo sapiens (human)Kd1.206512
Serine/threonine-protein kinase 32BHomo sapiens (human)Kd6.039235
Serine/threonine-protein kinase 32CHomo sapiens (human)Kd6.124035
Serine/threonine-protein kinase 33Homo sapiens (human)Kd4.038735
Serine/threonine-protein kinase 35Homo sapiens (human)Kd6.713323
Serine/threonine-protein kinase 36Homo sapiens (human)Kd7.716746
Serine/threonine-protein kinase 38Homo sapiens (human)Kd12.514034
Serine/threonine-protein kinase 38-likeHomo sapiens (human)Kd7.783858
Serine/threonine-protein kinase 4Homo sapiens (human)Kd6.680759
Serine/threonine-protein kinase A-RafHomo sapiens (human)Kd30.000014
Serine/threonine-protein kinase ATRHomo sapiens (human)Kd30.000012
Serine/threonine-protein kinase B-rafHomo sapiens (human)Kd14.6154713
Serine/threonine-protein kinase BRSK1Homo sapiens (human)Kd0.730435
Serine/threonine-protein kinase BRSK2Homo sapiens (human)Kd0.391435
Serine/threonine-protein kinase Chk1Homo sapiens (human)Kd8.003648
Serine/threonine-protein kinase Chk2Homo sapiens (human)Kd6.691323
Serine/threonine-protein kinase D1Homo sapiens (human)Kd6.010835
Serine/threonine-protein kinase D2Homo sapiens (human)Kd9.884248
Serine/threonine-protein kinase D3Homo sapiens (human)Kd8.709348
Serine/threonine-protein kinase DCLK1Homo sapiens (human)Kd6.044035
Serine/threonine-protein kinase DCLK2Homo sapiens (human)Kd6.029235
Serine/threonine-protein kinase DCLK3Homo sapiens (human)Kd6.006835
Serine/threonine-protein kinase ICKHomo sapiens (human)Kd10.521035
Serine/threonine-protein kinase LATS1Homo sapiens (human)Kd7.931448
Serine/threonine-protein kinase LATS2Homo sapiens (human)Kd1.326835
Serine/threonine-protein kinase MAKHomo sapiens (human)Kd7.533323
Serine/threonine-protein kinase MARK1Homo sapiens (human)Kd0.103635
Serine/threonine-protein kinase MARK2Homo sapiens (human)Kd3.529459
Serine/threonine-protein kinase MRCK alphaHomo sapiens (human)Kd15.014248
Serine/threonine-protein kinase MRCK betaHomo sapiens (human)Kd15.010548
Serine/threonine-protein kinase MRCK gammaHomo sapiens (human)Kd12.867747
Serine/threonine-protein kinase mTORHomo sapiens (human)Kd10.000012
Serine/threonine-protein kinase N1Homo sapiens (human)Kd0.429748
Serine/threonine-protein kinase N2Homo sapiens (human)Kd7.551448
Serine/threonine-protein kinase N3Homo sapiens (human)Kd30.000012
Serine/threonine-protein kinase Nek1Homo sapiens (human)Kd15.215048
Serine/threonine-protein kinase Nek11Homo sapiens (human)Kd6.550012
Serine/threonine-protein kinase Nek2Homo sapiens (human)Kd13.582259
Serine/threonine-protein kinase Nek3Homo sapiens (human)Kd22.000025
Serine/threonine-protein kinase Nek4Homo sapiens (human)Kd10.000012
Serine/threonine-protein kinase Nek5Homo sapiens (human)Kd6.324035
Serine/threonine-protein kinase Nek6Homo sapiens (human)Kd10.000035
Serine/threonine-protein kinase Nek7Homo sapiens (human)Kd6.500546
Serine/threonine-protein kinase Nek9Homo sapiens (human)Kd14.766759
Serine/threonine-protein kinase NIM1Homo sapiens (human)Kd6.713323
Serine/threonine-protein kinase NLKHomo sapiens (human)Kd15.055048
Serine/threonine-protein kinase OSR1Homo sapiens (human)Kd6.813323
Serine/threonine-protein kinase PAK 1Homo sapiens (human)Kd1.033946
Serine/threonine-protein kinase PAK 2Homo sapiens (human)Kd12.338348
Serine/threonine-protein kinase PAK 3Homo sapiens (human)Kd0.612546
Serine/threonine-protein kinase PAK 4Homo sapiens (human)Kd12.0365510
Serine/threonine-protein kinase PAK 5Homo sapiens (human)Kd5.000946
Serine/threonine-protein kinase PAK 6Homo sapiens (human)Kd11.250258
Serine/threonine-protein kinase pim-1Homo sapiens (human)Kd6.4139611
Serine/threonine-protein kinase pim-2Homo sapiens (human)Kd12.567559
Serine/threonine-protein kinase pim-3Homo sapiens (human)Kd0.336235
Serine/threonine-protein kinase PknBMycobacterium tuberculosis H37RvKd5.044012
Serine/threonine-protein kinase PLK1Homo sapiens (human)Kd6.076035
Serine/threonine-protein kinase PLK2Homo sapiens (human)Kd6.733323
Serine/threonine-protein kinase PLK3Homo sapiens (human)Kd6.364035
Serine/threonine-protein kinase PLK4Homo sapiens (human)Kd3.387459
Serine/threonine-protein kinase PRP4 homologHomo sapiens (human)Kd0.110023
Serine/threonine-protein kinase receptor R3Homo sapiens (human)Kd10.000035
Serine/threonine-protein kinase RIO1Homo sapiens (human)Kd0.772035
Serine/threonine-protein kinase RIO2Homo sapiens (human)Kd0.194723
Serine/threonine-protein kinase RIO3Homo sapiens (human)Kd0.265149
Serine/threonine-protein kinase SBK1Homo sapiens (human)Kd5.001612
Serine/threonine-protein kinase Sgk3Homo sapiens (human)Kd0.701712
Serine/threonine-protein kinase SIK1Homo sapiens (human)Kd0.096935
Serine/threonine-protein kinase SIK2Homo sapiens (human)Kd6.987749
Serine/threonine-protein kinase SIK3Homo sapiens (human)Kd10.703936
Serine/threonine-protein kinase STK11Homo sapiens (human)Kd11.396548
Serine/threonine-protein kinase TAO1Homo sapiens (human)Kd15.536847
Serine/threonine-protein kinase TAO2Homo sapiens (human)Kd20.002425
Serine/threonine-protein kinase TAO3Homo sapiens (human)Kd18.333436
Serine/threonine-protein kinase TBK1Homo sapiens (human)Kd5.227436
Serine/threonine-protein kinase TNNI3KHomo sapiens (human)Kd6.400035
Serine/threonine-protein kinase tousled-like 1Homo sapiens (human)Kd6.010835
Serine/threonine-protein kinase tousled-like 2Homo sapiens (human)Kd6.006435
Serine/threonine-protein kinase ULK1Homo sapiens (human)Kd18.335036
Serine/threonine-protein kinase ULK2Homo sapiens (human)Kd6.666923
Serine/threonine-protein kinase ULK3Homo sapiens (human)Kd10.451436
Serine/threonine-protein kinase ULK3Mus musculus (house mouse)Kd0.003011
Serine/threonine-protein kinase VRK2Homo sapiens (human)Kd10.000012
Serine/threonine-protein kinase/endoribonuclease IRE1Homo sapiens (human)Kd10.773336
Serine/threonine-protein kinase/endoribonuclease IRE2Homo sapiens (human)Kd20.302713
SNF-related serine/threonine-protein kinaseHomo sapiens (human)Kd5.045012
Sodium-dependent noradrenaline transporter Homo sapiens (human)EC5014.047011
Spike glycoproteinBetacoronavirus England 1EC5037.563313
Spike glycoproteinSevere acute respiratory syndrome-related coronavirusEC5037.563313
SRSF protein kinase 1Homo sapiens (human)Kd0.027435
SRSF protein kinase 2Homo sapiens (human)Kd0.224835
SRSF protein kinase 3Homo sapiens (human)Kd0.077723
STE20-like serine/threonine-protein kinase Homo sapiens (human)Kd7.107259
STE20-related kinase adapter protein alphaHomo sapiens (human)Kd30.000013
STE20/SPS1-related proline-alanine-rich protein kinaseHomo sapiens (human)Kd6.710023
streptokinase A precursorStreptococcus pyogenes M1 GASEC5078.086022
Structural maintenance of chromosomes protein 1AHomo sapiens (human)Kd30.000013
Structural maintenance of chromosomes protein 2Homo sapiens (human)Kd30.000013
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrialHomo sapiens (human)Kd30.000013
Testis-specific serine/threonine-protein kinase 1Homo sapiens (human)Kd2.889635
TGF-beta receptor type-1Homo sapiens (human)Kd14.019949
TGF-beta receptor type-2Homo sapiens (human)Kd17.500048
Thyroid hormone receptor-associated protein 3Homo sapiens (human)Kd30.000011
TRAF2 and NCK-interacting protein kinaseHomo sapiens (human)Kd3.873759
Transient receptor potential cation channel subfamily M member 6Homo sapiens (human)Kd10.000012
Transmembrane protease serine 2Homo sapiens (human)EC5037.563313
Tubulin alpha-1A chainRattus norvegicus (Norway rat)Kd1.935012
Tyrosine--tRNA ligase, cytoplasmicHomo sapiens (human)Kd30.000013
Tyrosine-protein kinase ABL1Homo sapiens (human)Kd5.85253963
Tyrosine-protein kinase ABL2Homo sapiens (human)Kd13.375659
Tyrosine-protein kinase BlkHomo sapiens (human)Kd0.306035
Tyrosine-protein kinase BTKHomo sapiens (human)Kd10.299759
Tyrosine-protein kinase CSKHomo sapiens (human)Kd14.7200510
Tyrosine-protein kinase FerHomo sapiens (human)Kd4.124259
Tyrosine-protein kinase Fes/FpsHomo sapiens (human)Kd16.671849
Tyrosine-protein kinase FgrHomo sapiens (human)Kd0.375746
Tyrosine-protein kinase FRKHomo sapiens (human)Kd10.838959
Tyrosine-protein kinase FynHomo sapiens (human)Kd10.713059
Tyrosine-protein kinase HCKHomo sapiens (human)Kd10.245859
Tyrosine-protein kinase ITK/TSKHomo sapiens (human)Kd6.007635
Tyrosine-protein kinase JAK1Homo sapiens (human)Kd12.8496611
Tyrosine-protein kinase JAK2Homo sapiens (human)Kd0.052346
Tyrosine-protein kinase JAK3Homo sapiens (human)Kd0.011635
Tyrosine-protein kinase LckHomo sapiens (human)Kd12.0920510
Tyrosine-protein kinase LynHomo sapiens (human)Kd11.432259
Tyrosine-protein kinase MerHomo sapiens (human)Kd5.536347
Tyrosine-protein kinase receptor Tie-1Homo sapiens (human)Kd0.866035
Tyrosine-protein kinase receptor TYRO3Homo sapiens (human)Kd5.108046
Tyrosine-protein kinase receptor UFOHomo sapiens (human)Kd0.374735
Tyrosine-protein kinase SrmsHomo sapiens (human)Kd6.296035
Tyrosine-protein kinase SYKHomo sapiens (human)Kd4.452259
Tyrosine-protein kinase TecHomo sapiens (human)Kd15.325048
Tyrosine-protein kinase TXKHomo sapiens (human)Kd6.092035
Tyrosine-protein kinase YesHomo sapiens (human)Kd10.333759
Tyrosine-protein kinase ZAP-70Homo sapiens (human)Kd1.577635
U5 small nuclear ribonucleoprotein 200 kDa helicaseHomo sapiens (human)Kd30.000013
Uncharacterized aarF domain-containing protein kinase 5Homo sapiens (human)Kd30.000012
Uncharacterized protein FLJ45252Homo sapiens (human)Kd10.104713
Uncharacterized serine/threonine-protein kinase SBK3Homo sapiens (human)Kd6.675023
Vascular endothelial growth factor receptor 1 Homo sapiens (human)Kd0.330035
Vascular endothelial growth factor receptor 2Homo sapiens (human)Kd1.718346
Vascular endothelial growth factor receptor 3Homo sapiens (human)Kd0.349546
Very long-chain specific acyl-CoA dehydrogenase, mitochondrialHomo sapiens (human)Kd30.000013
Wee1-like protein kinaseHomo sapiens (human)Kd14.725048
Wee1-like protein kinase 2Homo sapiens (human)Kd10.000023
Zinc finger protein mex-5Caenorhabditis elegansEC5014.047011

Other Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
cAMP-dependent protein kinase catalytic subunit alpha isoform Calpha1Homo sapiens (human)AC500.126011
Estrogen receptorRattus norvegicus (Norway rat)A500.020011
Estrogen receptorHomo sapiens (human)DC500.091011
Estrogen receptor betaRattus norvegicus (Norway rat)A500.020011
interferon gamma precursorHomo sapiens (human)AC5035.240011
Neuraminidase Influenza A virus (A/Wilson-Smith/1933(H1N1))Kiuc43.000011
Prolyl 4-hydroxylase, beta polypeptideHomo sapiens (human)AC509.800022
Receptor-type tyrosine-protein phosphatase betaHomo sapiens (human)Kis125.700011
UDP-glucuronosyltransferase 1A4Homo sapiens (human)Km32.000011