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aminoacridines
Acridines which are substituted in any position by one or more amino groups or substituted amino groups. Note that the term 'aminoacridine' is the International Prorietary Name (INN) for 9-aminoacridine.
ChEBI ID: 51803
Members (5)
| Member | Definition | Role |
|---|---|---|
| acridine half-mustard | A member of the class of aminoacridines that is acridine which is substituted by a methoxy group at position 2, chlorine at position 6, and a {3-[(2-chloroethyl)amino]propyl}amino group at position 9. | acridine half-mustard |
| acridine orange | A member of the class of aminoacridines that is acridine carrying two dimethylamino substituents at positions 3 and 6. The hydrochloride salt is the fluorescent dye 'acridine orange', used for cell cycle determination. | acridine orange free base |
| acridine yellow | acridine yellow | |
| aminacrine | An aminoacridine that is acridine in which the hydrogen at position 9 is replaced by an amino group. A fluorescent dyd and topical antiseptic agent, it is used (usually as the hydrochloride salt) in eye drops for the treatment of superficial eye infections. | 9-aminoacridine |
| proflavine | An aminoacridine that is acridine that is substituted by amino groups at positions 3 and 6. A slow-acting bacteriostat that is effective against many Gram-positive bacteria (but ineffective against spores), its salts were formerly used for treatment of burns and infected wounds. | 3,6-diaminoacridine |
Research
Studies (3,158)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1,323 (41.89) | 18.7374 |
| 1990's | 628 (19.89) | 18.2507 |
| 2000's | 649 (20.55) | 29.6817 |
| 2010's | 464 (14.69) | 24.3611 |
| 2020's | 94 (2.98) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 35 (1.00%) | 5.53% |
| Reviews | 47 (1.34%) | 6.00% |
| Case Studies | 25 (0.71%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 3,395 (96.94%) | 84.16% |