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allylamine antifungal drug
An organonitrogen compound that contains an amino group that is attached to a carbon which is itself attached to an olefinic carbon and which has been used as an antifungal drug.
ChEBI ID: 87127
Members (4)
| Member | Definition | Role |
|---|---|---|
| naftifine | A tertiary amine in which the nitrogen is substituted by methyl, alpha-naphthylmethyl, and (1E)-cinnamyl groups. It is used (usually as its hydrochloride salt) for the treatment of fungal skin infections. | naftifine |
| naftifine hydrochloride | Naftifine hydrochloride | |
| terbinafine | A tertiary amine that is N-methyl-1-naphthalenemethylamine in which the amino hydrogen is replaced by a 3-(tertbutylethynyl)allyl group. An antifungal agent administered orally (generally as the hydrochloride salt) for the treatment of skin and nail infections. | terbinafine |
| terbinafine hydrochloride | A hydrochloride obtained by reaction of terbinafine with one molar equivalent of hydrogen chloride. | terbinafine hydrochloride |
Research
Studies (2,113)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 87 (4.12) | 18.7374 |
| 1990's | 458 (21.68) | 18.2507 |
| 2000's | 646 (30.57) | 29.6817 |
| 2010's | 640 (30.29) | 24.3611 |
| 2020's | 282 (13.35) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 316 (13.52%) | 5.53% |
| Reviews | 310 (13.26%) | 6.00% |
| Case Studies | 593 (25.37%) | 4.05% |
| Observational | 2 (0.09%) | 0.25% |
| Other | 1,116 (47.75%) | 84.16% |