A Daphnia metabolite produced by the species Daphnia tenebrosa.
ChEBI ID: 83146
| Member | Definition | Class |
|---|---|---|
| cetoleic acid | A docosenoic acid having a cis-double bond at position 11. | cetoleic acid |
| docosahexaenoate | A docosahexaenoic acid having six cis-double bonds at positions 4, 7, 10, 13, 16 and 19. | all-cis-docosa-4,7,10,13,16,19-hexaenoic acid |
| lignoceric acid | A C24 straight-chain saturated fatty acid. | tetracosanoic acid |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 47 (20.98) | 18.7374 |
| 1990's | 45 (20.09) | 18.2507 |
| 2000's | 49 (21.88) | 29.6817 |
| 2010's | 73 (32.59) | 24.3611 |
| 2020's | 10 (4.46) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 5 (2.16%) | 5.53% |
| Reviews | 6 (2.60%) | 6.00% |
| Case Studies | 3 (1.30%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 217 (93.94%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 28.1950 | 1 | 3 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 21.3138 | 1 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 11.6723 | 1 | 3 |
| geminin | Homo sapiens (human) | Potency | 33.4983 | 1 | 1 |
| GLS protein | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 17.3960 | 2 | 3 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 79.4328 | 1 | 2 |
| TDP1 protein | Homo sapiens (human) | Potency | 27.3500 | 2 | 4 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 33.4915 | 2 | 2 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 34.8250 | 1 | 3 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Aromatase | Homo sapiens (human) | IC50 | 33.2000 | 1 | 1 |
| Caspase-1 | Homo sapiens (human) | IC50 | 6.7600 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | Ki | 6.2920 | 1 | 1 |
| Oxoeicosanoid receptor 1 | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | IC50 | 15.0000 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | IC50 | 9.8000 | 1 | 1 |
| Retinoic acid receptor RXR-alpha | Homo sapiens (human) | Ki | 6.2920 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Chain A, Fatty Acid-binding Protein, Brain | Homo sapiens (human) | Kd | 0.0534 | 1 | 2 |
| Free fatty acid receptor 1 | Homo sapiens (human) | EC50 | 23.8500 | 2 | 2 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Retinoic acid receptor RXR-alpha | Homo sapiens (human) | ED50 | 50.0000 | 1 | 1 |