Roles > protein kinase agonist
Page last updated: 2024-08-05 15:35:11
protein kinase agonist
An agonist that selectively binds to and activates a protein kinase receptor.
ChEBI ID: 64106
Members (4)
| Member | Definition | Class |
|---|
| 8-((4-chlorophenyl)thio)cyclic-3',5'-amp | A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic AMP in which the hydrogen at position 2 on the purine fragment is replaced by a 4-chlorophenylthio group. | 8-(4-chlorophenylthio)-cAMP |
| 8-((4-chlorophenyl)thio)cyclic-3',5'-gmp | A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic GMP in which the hydrogen at position 2 on the purine fragment is replaced by a 4-chlorophenylthio group. | 8-(4-chlorophenylthio)-cGMP |
| 8-bromo cyclic adenosine monophosphate | A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic AMP bearing an additional bromo substituent at position 8 on the adenine ring. An activator of cyclic AMP-dependent protein kinase, but resistant to degradation by cyclic AMP phosphodiesterase. | 8-Br-cAMP |
| monobutyryl cyclic amp | A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic AMP in which the exocyclic amino group on the purine fragment is carrying a butyryl substituent. | N(6)-butyryl-cAMP |
Research
Studies (4,271)
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|
| pre-1990 | 1,003 (23.48) | 18.7374 |
| 1990's | 1,930 (45.19) | 18.2507 |
| 2000's | 1,040 (24.35) | 29.6817 |
| 2010's | 288 (6.74) | 24.3611 |
| 2020's | 10 (0.23) | 2.80 |
Study Types
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|
| Trials | 5 (0.11%) | 5.53% |
| Reviews | 32 (0.72%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 4,404 (99.17%) | 84.16% |
Protein Targets (4)
Inhibition Measurements