Page last updated: 2024-08-05 12:25:54
sapogenin
Any organic polycyclic compound that is the aglycon moiety of a saponin; sapogenins may be steroids or triterpenoids.
ChEBI ID: 26606
Members (8)
Member | Definition | Role |
---|---|---|
diosgenin | A sapogenin that is spirostan which is substituted by a hydroxy group at the 3beta position, contains a double bond at the 5-6 position, and has R- configuration at position 25. A natural product found in Dioscorea (wild yam) species, it is used as the starting point for the commercial synthesis of a number of steroids, including cortisone, pregnenolone and progesterone. | diosgenin |
gypsogenin | A sapogenin that is olean-12-en-28-oic acid substituted by a beta-hydroxy group at position 3 and an oxo group at position 23. | gypsogenin |
hederagenin | A sapogenin that is olean-12-en-28-oic acid substituted by hydroxy groups at positions 3 and 23 (the 3beta stereoisomer). | hederagenin |
nuatigenin | nuatigenin | |
protopanaxatriol | A tetracyclic triterpenoid sapogenin (isolated from ginseng and notoginseng) that is that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions and in which a double bond has been introduced at the 24-25 position. | protopanaxatriol |
sarsasapogenin | (25S)-5beta-spirostan-3beta-ol | |
sarsasapogenin, (3beta,5alpha,25r)-isomer | A widely used steroidal sapogenin isolated from several plant species and used for synthesizing steroid drugs. | tigogenin |
solasodine | An oxaspiro compound and steroid alkaloid sapogenin with formula C27H43NO2 found in the Solanum (nightshade) family. It is used as a precursor in the synthesis of complex steroidal compounds such as contraceptive pills. | solasodine |
Research
Studies (1,312)
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
---|---|---|
pre-1990 | 76 (5.79) | 18.7374 |
1990's | 68 (5.18) | 18.2507 |
2000's | 246 (18.75) | 29.6817 |
2010's | 642 (48.93) | 24.3611 |
2020's | 280 (21.34) | 2.80 |
Study Types
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
---|---|---|
Trials | 7 (0.51%) | 5.53% |
Reviews | 61 (4.43%) | 6.00% |
Case Studies | 3 (0.22%) | 4.05% |
Observational | 1 (0.07%) | 0.25% |
Other | 1,306 (94.78%) | 84.16% |