Page last updated: 2024-09-28

Cyst, Lymphatic

Cystic mass containing lymph from diseased lymphatic channels or following surgical trauma or other injury.

Synonyms(4)

Synonym
Lymphocele
Lymphatic Cyst
Cyst, Lymphatic
Lymphocoele

Research Excerpts

Overview

ExcerptReference
"Lymphocele is a well recognized complication of renal transplant surgery."( Anderson, JH; Blue, PW; Fortenbery, EJ; Van Nostrand, D, 1990)
"Lymphocele is a rare cause of impairment of graft function after renal transplantation."( Abendroth, D; Kunz, R; Schilling, M, 1995)
"Postoperative lymphocele is a well-documented complication of gynecological operations involving pelvic and retroperitoneal lymph node dissection."( Kaplan, O; Klausner, J; Papo, J; Ravid, A, 1994)
"The exact cause of lymphoceles is uncertain, but acquired lymphoceles have been reported secondary to tissue trauma or surgery in human beings."( Burns, J; Kirpensteijn, J; Layton, CE; Reynhout, KM, 1994)
"A retroperitoneal lymphocele is an uncommon complication caused by the surgical exposure of the lumbar spine when a ventral approach is used."( Levi, AD, 1999)
"Lymphocele is a common cause of fluid collection in post-renal transplant patients."( Bharathi Dasan, J; Choudhury, S; Guleria, S; Kumar, R; Malhotra, A; Padhy, AK, 2003)
"Lymphoceles are frequent complications of pelvic lymph node dissection."( Hegele, A; Hofmann, R; Olbert, P; Schrader, AJ; Varga, Z, 2006)
"Lymphocele is a complication of renal transplantation, representing a lymphatic collection around the grafted kidney."( Castagneto, M; Citterio, F; Massa, A; Nanni, G; Romagnoli, J; Salerno, MP; Tondolo, V, 2006)
"Lymphocele is a special complication following kidney transplantation."( Járay, J; Kahan, BD; Langer, R; Máthé, Z; Remport, A; Tóth, A, 2007)
"Lymphoceles are common surgical complications of renal transplantation."( Buhluli, A; Zomorrodi, A, 2007)
"Lymphocele is a lymph collection that forms after surgery following injury to lymph nodes and vessels."( Chudek, J; Cierpka, L; Kolonko, A; Król, R; Kunsdorf-Wnuk, A; Mały, A; Pawlicki, J; Wiecek, A; Ziaja, J, 2007)
"Inguinal lymphocele is a well-known complication after inguinofemoral lymph node dissection for penile cancer, and a variety of curative approaches have been reported."( Giannarini, G; Mariani, C; Minervini, A; Minervini, R; Morelli, A; Morelli, G; Pagni, R, 2009)
"Lymphocele is a common pathology after a renal transplantation which needs to be treated depending on its clinical manifestations."( Alvarez Castelo, L; Casas Agudo, P; Chantada Abal, V; González Dacal, J; González Martín, M; Janeiro Pais, JM; López García, D; Martínez Breijo, S; Ruibal Moldes, M; Zarraonandía Andraca, A, 2009)
"Lymphocele is a well-known complication of renal transplantation."( Chebil, M; Derouiche, A; El Atat, R; Ezzeddine, A; Garbouj, N; Khaled, A; Mechri, M, 2010)
"Inguinal lymphocele is a well-known complication of inguinal lymph node dissection."( Fujisawa, Y; Furuta, J; Kawachi, Y; Maruyama, H; Nakamura, Y; Otsuka, F, 2011)
"PCD of symptomatic lymphoceles is an effective postoperative management technique."( Alago, W; Brown, KT; Covey, AM; Dalbagni, G; Deodhar, A; Getrajdman, GI; Michell, H; Sofocleous, CT; Solomon, SB, 2013)
"The lymphocele is the most frequently encountered complication after axillary dissection performed for breast cancer (15-81%)."( Body, G; Lacoste, C; Marret, H; Ouldamer, L, 2013)
"Lymphoceles are among the most common postoperative complications of pelvic lymphadenectomy (PL), with a reported incidence of 1% to 50%."( Giorda, G; Guido, M; Malvasi, A; Mynbaev, OA; Nezhat, FR; Tinelli, A; Tsin, DA, 2013)
"Lymphoceles are a common complication after pelvic lymphadenectomy in women with gynecologic malignancies."( Cibula, D; Grimm, C; Helmy, S; Polterauer, S; Reinthaller, A; Tempfer, C; Zikan, M, 2014)
"Lymphocele is the most common complication after pelvic lymph node dissection (PLND)."( Danuser, H; Di Pierro, GB; Ferrari, M; Grande, P; Mattei, A; Mordasini, L; Würnschimmel, C, 2017)
"Lymphoceles are well-known complications after pediatric kidney transplantation (KT)."( Ariceta, G; Asensio, M; Coma, A; Gander, R; Molino, JA; Perez, M; Royo, GF; Vilalta, R, 2017)
"Development of a lymphocele is a frequent complication after pelvic lymph node dissection (PLND) for nodal staging in prostate cancer."( Buelens, S; Decaestecker, K; Lumen, N; Poelaert, F; Van Huele, A; Van Praet, C, 2018)
"Lymphocele is a well-known postoperative surgical complication after kidney transplant."( Ayar, Y; Aydin, MF; Coskun, B; Ersoy, A; Isiktas Sayilar, E; Kaygisiz, O; Kordan, Y; Sahin, AB; Vuruskan, H; Yildiz, A, 2022)
"Lymphocele is a collection of lymphatic fluid within the body."( Fritsche, E; Meroni, M; Scaglioni, MF, 2021)
"Post-transplant lymphocele is a common complication with a potentially severe course and may require percutaneous drainage or open/percutaneous surgical intervention."( Acikgoz, O; Akinci, S, 2023)
"Lymphocele is a frequent complication after kidney transplant and needs attention."( Hou, J; Hu, L; Huang, Y; Hui, Y; Jiang, H; Wang, L; Wei, X; Zhou, Z, 2023)

Treatment

ExcerptReference
"Outpatient treatment of lymphoceles following arterial reconstructive procedures can be performed safely."( Bracale, U; Di Lella, D; Iandoli, R; Porcellini, M; Spinetti, F, 2002)
"Because we diagnosed lymphatic cysts caused by the delayed lymphatic discharge after lymphadenectomy, an administration of OK-432 into cysts was performed."( Fujimoto, T; Hiramatsu, Y; Isohata, N; Matsumoto, A; Ogawa, K; Osawa, G; Otani, T; Umehara, A; Watanabe, K; Yokomizo, H; Yoshimatsu, K, 2008)
"A total of 32 procedures for the treatment of lymphocele were performed in 14 of these patients."( Chacko, N; Choudhrie, AV; Devasia, A; Gnanaraj, L; Kekre, NS; Kumar, S, 2012)
"However, there is no standard treatment for lymphoceles, and the literature lacks consensus on which is the most appropriate approach."( Ariceta, G; Asensio, M; Coma, A; Gander, R; Molino, JA; Perez, M; Royo, GF; Vilalta, R, 2017)
"There is no gold-standard treatment for lymphoceles in children, and reports in the literature on the topic are scarce."( Ariceta, G; Asensio, M; Coma, A; Gander, R; Molino, JA; Perez, M; Royo, GF; Vilalta, R, 2017)

Research

Studies (163)

TimeframeStudies, This Condition (%)All Conditions %
pre-19905 (3.07)23.3326
1990's37 (22.70)12.5806
2000's45 (27.61)18.1394
2010's61 (37.42)28.8240
2020's15 (9.20)9.53
DrugIndicatedRelationship StrengthStudiesTrials
dalteparin0low10
albendazole0low10
diatrizoic acid0low10
azathioprine0low20
pentetic acid0low10
fluorouracil0low10
ticlopidine0low10
prednisolone0low20
prednisone0low40
methylene blue0low50
ampicillin0low10
methylprednisolone0low10
n-vinyl-2-pyrrolidinone0low20
sulfan blue0low30
meglumine0low10
iodohippuric acid0low10
c.i. 425100low80
vancomycin0low10
enbucrilate0low100
technetium0low10
titanium0medium11
iso-sulfan blue0low60
aromasil0low10
clopidogrel0low10
technetium tc 99m mertiatide0low20
cephalosporin c0low10
fluorodeoxyglucose f180low10
fibrinogen0medium157
sulbactam0low10
technetium tc 99m pentetate0low50
povidone-iodine0low150
fibrin0medium11
sultamicillin0low10
tacrolimus0medium62
mycophenolic acid0medium104
bromochloroacetic acid0low10
squalene0low10
picibanil0low80
polidocanol0low10
sirolimus0medium173
antimony0low10
cysteine0low10
everolimus0medium41
gadolinium dtpa0low20
amoxicillin-potassium clavulanate combination0low10
pasireotide0medium11
losartan potassium0low10
dextrothyroxine0low10
indocyanine green0medium81
sodium tetradecyl sulfate0low10
ro13-99040low20
interleukin-80low10
methylcellulose0low10
tetracycline0low80
oxytetracycline, anhydrous0low10
technetium tc 99m sulfur colloid0low10
vitamin b 120low10
cyclosporine0medium82
technetium tc 99m-ethylenedicysteine0low10

Protein Targets (762)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
estrogen nuclear receptor alpha230023
Free fatty acid receptor 30011
Free fatty acid receptor 20112
Tyrosine-protein kinase Lck0033
Tyrosine-protein kinase Fyn0033
Fibrinogen C domain-containing protein 10101
Chain A, Beta-lactamase3003
Luciferase8008
glp-1 receptor, partial6006
hypoxia-inducible factor 1 alpha subunit7007
RAR-related orphan receptor gamma130013
ATAD5 protein, partial5005
Fumarate hydratase4004
TDP1 protein160016
GLI family zinc finger 3150015
AR protein210021
caspase 7, apoptosis-related cysteine protease4004
nuclear receptor subfamily 1, group I, member 3120012
progesterone receptor120012
glucocorticoid receptor [Homo sapiens]170017
retinoic acid nuclear receptor alpha variant 1130013
retinoid X nuclear receptor alpha110011
estrogen-related nuclear receptor alpha160016
farnesoid X nuclear receptor110011
pregnane X nuclear receptor140014
polyprotein4004
67.9K protein4004
peroxisome proliferator activated receptor gamma110011
vitamin D (1,25- dihydroxyvitamin D3) receptor7007
caspase-34004
IDH16006
euchromatic histone-lysine N-methyltransferase 2100010
aryl hydrocarbon receptor7007
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a140014
v-jun sarcoma virus 17 oncogene homolog (avian)110011
nuclear receptor subfamily 1, group I, member 26006
Histone H2A.x9009
cellular tumor antigen p53 isoform a2002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 14004
chromobox protein homolog 18008
nuclear factor erythroid 2-related factor 2 isoform 28008
transcriptional regulator ERG isoform 32002
thyroid hormone receptor beta isoform 2170017
histone deacetylase 9 isoform 34004
heat shock protein beta-16006
mitogen-activated protein kinase 13003
urokinase-type plasminogen activator precursor5005
plasminogen precursor5005
urokinase plasminogen activator surface receptor precursor5005
geminin160016
Vif0001
peripheral myelin protein 228008
survival motor neuron protein isoform d5005
muscleblind-like protein 1 isoform 16006
DNA dC->dU-editing enzyme APOBEC-3G isoform 12002
lamin isoform A-delta108008
neuropeptide S receptor isoform A3003
ATP-binding cassette sub-family C member 3012012
Multidrug resistance-associated protein 4012012
Voltage-dependent calcium channel gamma-2 subunit100010
Bile salt export pump014014
Interferon beta100010
Cellular tumor antigen p53170017
Integrin beta-31001
Integrin alpha-IIb1001
Methionine aminopeptidase0101
Glutamate receptor 2101011
Fatty-acid amide hydrolase 10101
Inositol monophosphatase 12002
Canalicular multispecific organic anion transporter 1011011
ATPase family AAA domain-containing protein 5130013
Ataxin-2130013
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE7007
Chain A, Mutant Al2 6e7p9g0011
Chain A, 2-oxoglutarate Oxygenase5005
Chain A, ATP-DEPENDENT DNA HELICASE Q13003
Chain A, Cruzipain2002
Beta-lactamase 0001
acid sphingomyelinase1001
GLS protein2002
apical membrane antigen 1, AMA13003
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase type 20001
Metallo-beta-lactamase VIM-11 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0102
Metallo-beta-lactamase0001
Beta-lactamase 0001
DNA polymerase beta4004
DNA polymerase eta isoform 14004
DNA polymerase iota isoform a (long)7007
DNA polymerase kappa isoform 15005
Carbonic anhydrase 10101
Carbonic anhydrase 20101
60 kDa heat shock protein, mitochondrial0202
Beta-lactamase OXA-70001
Solute carrier family 15 member 10202
Solute carrier family 15 member 10101
Spike glycoprotein8008
10 kDa heat shock protein, mitochondrial0202
Angiopoietin-1 receptor0011
Beta-lactamase 0102
Beta-lactamase 0102
Beta-lactamase 0102
Solute carrier family 15 member 20101
Thiosulfate sulfurtransferase0202
Metallo-beta-lactamase VIM-130001
Efflux transporter 0001
Beta-lactamase 0001
Beta-lactamase Toho-10001
Beta-lactamase 0001
Class D beta-lactamase0102
60 kDa chaperonin 0202
Metallo-beta-lactamase0001
Solute carrier family 15 member 20101
Beta-lactamase 0102
Beta-lactamase 0001
10 kDa chaperonin 0202
Metallo-b-lactamase 0002
Carbapenem-hydrolyzing beta-lactamase KPC0102
Histamine H3 receptor0001
Beta-lactamase class B VIM-2 0002
Beta-lactamase VIM-1 0001
ATP-dependent phosphofructokinase5005
SMAD family member 25005
PPM1D protein3003
SMAD family member 35005
thioredoxin glutathione reductase5005
G8008
peroxisome proliferator-activated receptor delta9009
nuclear factor erythroid 2-related factor 2 isoform 1130013
HLA class I histocompatibility antigen, B alpha chain 8008
Aromatase0303
Inositol hexakisphosphate kinase 18008
cytochrome P450 2C9, partial8008
Chain A, TYROSYL-DNA PHOSPHODIESTERASE5005
Chain A, Ferritin light chain5005
interleukin 82002
acetylcholinesterase8008
thioredoxin reductase5005
phosphopantetheinyl transferase4004
Microtubule-associated protein tau5005
EWS/FLI fusion protein5005
P531001
arylsulfatase A3003
thyroid stimulating hormone receptor9009
activating transcription factor 66006
Bloom syndrome protein isoform 14004
peripheral myelin protein 22 isoform 14004
hemoglobin subunit beta2002
cytochrome P450 3A4 isoform 13003
M-phase phosphoprotein 83003
muscarinic acetylcholine receptor M11001
Gamma-aminobutyric acid receptor subunit pi3003
Bile salt export pump0202
Gamma-aminobutyric acid receptor subunit beta-13003
Gamma-aminobutyric acid receptor subunit delta3003
Gamma-aminobutyric acid receptor subunit gamma-23003
Gamma-aminobutyric acid receptor subunit alpha-53003
Gamma-aminobutyric acid receptor subunit alpha-33003
Gamma-aminobutyric acid receptor subunit gamma-13003
Gamma-aminobutyric acid receptor subunit alpha-23003
Gamma-aminobutyric acid receptor subunit alpha-43003
Gamma-aminobutyric acid receptor subunit gamma-33003
Gamma-aminobutyric acid receptor subunit alpha-63003
Nuclear receptor ROR-gamma3003
Gamma-aminobutyric acid receptor subunit alpha-13003
Gamma-aminobutyric acid receptor subunit beta-33003
Gamma-aminobutyric acid receptor subunit beta-23003
GABA theta subunit3003
Gamma-aminobutyric acid receptor subunit epsilon3003
Protein-arginine deiminase type-40202
aldehyde dehydrogenase 1 family, member A16006
nonstructural protein 15005
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
Cytochrome P450 2C80202
Cytochrome P450 2B60303
Liver carboxylesterase 10001
Sodium-dependent serotonin transporter0202
Cytochrome P450 2C190404
Rap guanine nucleotide exchange factor 41001
P2Y purinoceptor 120202
endonuclease IV3003
glucocerebrosidase1001
potassium voltage-gated channel subfamily H member 2 isoform d4004
USP1 protein, partial7007
vitamin D3 receptor isoform VDRA4004
nuclear receptor ROR-gamma isoform 15005
Bone morphogenetic protein receptor type-1B0022
Cell division cycle 7-related protein kinase0022
Serine/threonine-protein kinase PLK40022
ATP-dependent RNA helicase DDX3X0022
Pyridoxal kinase0022
Citron Rho-interacting kinase0022
Serine/threonine-protein kinase Chk10022
Aurora kinase A0022
Cyclin-G-associated kinase0022
Ephrin type-B receptor 60022
Peroxisomal acyl-coenzyme A oxidase 30022
Receptor-interacting serine/threonine-protein kinase 20022
Mitotic checkpoint serine/threonine-protein kinase BUB10022
Dynamin-like 120 kDa protein, mitochondrial0022
Eukaryotic translation initiation factor 5B0022
Rho-associated protein kinase 20022
Serine/threonine-protein kinase ULK10022
Serine/threonine-protein kinase/endoribonuclease IRE10022
Ribosomal protein S6 kinase alpha-50022
U5 small nuclear ribonucleoprotein 200 kDa helicase0022
Ribosomal protein S6 kinase alpha-40022
Serine/threonine-protein kinase 160022
Serine/threonine-protein kinase 100022
Serine/threonine-protein kinase D30022
Structural maintenance of chromosomes protein 20022
Mitogen-activated protein kinase kinase kinase 60022
Mitogen-activated protein kinase kinase kinase kinase 40022
Serine/threonine-protein kinase LATS10022
Serine/threonine-protein kinase PAK 40022
Tyrosine-protein kinase ABL10022
Epidermal growth factor receptor0123
High affinity nerve growth factor receptor0022
Guanine nucleotide-binding protein G(i) subunit alpha-20011
ADP/ATP translocase 20022
Protein kinase C beta type0022
Insulin receptor0022
Cyclin-dependent kinase 10022
Glycogen phosphorylase, liver form0022
Tyrosine-protein kinase Fes/Fps0022
Adenine phosphoribosyltransferase0022
Tyrosine-protein kinase Yes0022
Tyrosine-protein kinase Lyn0022
Proto-oncogene tyrosine-protein kinase receptor Ret0022
Insulin-like growth factor 1 receptor0022
Signal recognition particle receptor subunit alpha0022
Cytochrome c1, heme protein, mitochondrial0022
Hepatocyte growth factor receptor0022
Tyrosine-protein kinase HCK0022
Platelet-derived growth factor receptor beta0022
Tyrosine-protein kinase Fgr0022
Serine/threonine-protein kinase A-Raf0022
Glycogen phosphorylase, brain form0022
Breakpoint cluster region protein0022
Serine/threonine-protein kinase pim-10022
Fibroblast growth factor receptor 10022
DNA topoisomerase 2-alpha0022
Cyclin-dependent kinase 40022
ADP/ATP translocase 30022
Inosine-5'-monophosphate dehydrogenase 20224
Proto-oncogene tyrosine-protein kinase Src0022
cAMP-dependent protein kinase type II-alpha regulatory subunit0022
Serine/threonine-protein kinase B-raf0022
Potassium voltage-gated channel subfamily E member 10101
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0022
Ribosyldihydronicotinamide dehydrogenase [quinone]0022
Tyrosine-protein kinase Fer0022
Protein kinase C alpha type0022
cAMP-dependent protein kinase catalytic subunit alpha0022
General transcription and DNA repair factor IIH helicase subunit XPD0022
Casein kinase II subunit alpha'0022
Ras-related protein Rab-6A0022
Ephrin type-A receptor 10022
Multifunctional protein ADE20022
cAMP-dependent protein kinase catalytic subunit gamma0011
cAMP-dependent protein kinase catalytic subunit beta0022
Ferrochelatase, mitochondrial0022
Ribosomal protein S6 kinase beta-10022
Tyrosine-protein kinase JAK10022
Cyclin-dependent kinase 20022
Beta-adrenergic receptor kinase 10022
Probable ATP-dependent RNA helicase DDX60022
Mitogen-activated protein kinase 3 0022
MAP/microtubule affinity-regulating kinase 30022
Deoxycytidine kinase0022
Mitogen-activated protein kinase 10022
Ephrin type-A receptor 20022
Ephrin type-B receptor 20022
Non-receptor tyrosine-protein kinase TYK20022
UMP-CMP kinase 0022
Phosphatidylethanolamine-binding protein 10022
Wee1-like protein kinase0022
Heme oxygenase 20022
S-adenosylmethionine synthase isoform type-20022
DnaJ homolog subfamily A member 10022
RAC-alpha serine/threonine-protein kinase0022
RAC-beta serine/threonine-protein kinase0022
Dual specificity protein kinase TTK0022
DNA replication licensing factor MCM40022
Myosin-100022
Dual specificity mitogen-activated protein kinase kinase 20022
Receptor-type tyrosine-protein kinase FLT30022
Bone morphogenetic protein receptor type-1A0022
Activin receptor type-1B0022
TGF-beta receptor type-10022
TGF-beta receptor type-20022
Electron transfer flavoprotein subunit beta0022
Tyrosine-protein kinase CSK0022
Glycine--tRNA ligase0022
Protein kinase C iota type0022
Exosome RNA helicase MTR40022
Serine/threonine-protein kinase mTOR0325
Tyrosine-protein kinase Tec0022
Tyrosine-protein kinase ABL20022
Tyrosine-protein kinase FRK0022
G protein-coupled receptor kinase 60022
Tyrosine-protein kinase SYK0022
26S proteasome regulatory subunit 6B0022
Mitogen-activated protein kinase 80022
Mitogen-activated protein kinase 90022
Dual specificity mitogen-activated protein kinase kinase 30022
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0022
Casein kinase I isoform alpha0022
Casein kinase I isoform delta0022
MAP kinase-activated protein kinase 20022
Elongation factor Tu, mitochondrial0022
Choline-phosphate cytidylyltransferase A0022
Cysteine--tRNA ligase, cytoplasmic0022
Casein kinase I isoform epsilon0022
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0022
Dual specificity protein kinase CLK10022
Dual specificity protein kinase CLK20022
Dual specificity protein kinase CLK30022
Glycogen synthase kinase-3 alpha0022
Glycogen synthase kinase-3 beta0022
Cyclin-dependent kinase 70022
Cyclin-dependent kinase 90022
Ras-related protein Rab-27A0022
Interleukin-1 receptor-associated kinase 10022
Potassium voltage-gated channel subfamily KQT member 10101
Ribosomal protein S6 kinase alpha-30022
Serine/threonine-protein kinase Nek20022
Serine/threonine-protein kinase Nek30022
Dual specificity mitogen-activated protein kinase kinase 60022
Serine/threonine-protein kinase PLK10022
LIM domain kinase 10022
LIM domain kinase 20022
Mitogen-activated protein kinase 100022
Tyrosine--tRNA ligase, cytoplasmic0022
5'-AMP-activated protein kinase subunit gamma-10022
Ephrin type-B receptor 30022
Ephrin type-A receptor 50022
Ephrin type-B receptor 40022
Ephrin type-A receptor 40022
Adenylate kinase 2, mitochondrial0022
Adenosine kinase0022
Ras-related protein Rab-100022
Actin-related protein 30022
Actin-related protein 20022
GTP-binding nuclear protein Ran0022
Casein kinase I isoform gamma-20022
Cyclin-dependent kinase 30011
Cyclin-dependent kinase 60022
Cyclin-dependent-like kinase 5 0022
Cyclin-dependent kinase 160022
Cyclin-dependent kinase 170022
ATP-dependent 6-phosphofructokinase, platelet type0022
Dual specificity mitogen-activated protein kinase kinase 10022
DNA topoisomerase 2-beta0022
Protein kinase C theta type0022
Activin receptor type-10022
Macrophage-stimulating protein receptor0022
Focal adhesion kinase 10022
Protein kinase C delta type0022
Tyrosine-protein kinase BTK0022
Activated CDC42 kinase 10022
Epithelial discoidin domain-containing receptor 10022
Potassium voltage-gated channel subfamily H member 20101
Mitogen-activated protein kinase kinase kinase kinase 20022
Serine/threonine-protein kinase 40022
5'-AMP-activated protein kinase catalytic subunit alpha-10022
Dual specificity mitogen-activated protein kinase kinase 50022
Mitogen-activated protein kinase 70022
Serine/threonine-protein kinase PAK 20022
Serine/threonine-protein kinase 30022
Mitogen-activated protein kinase kinase kinase 10022
Integrin-linked protein kinase0022
Rho-associated protein kinase 10022
Non-receptor tyrosine-protein kinase TNK10022
Calcium/calmodulin-dependent protein kinase type II subunit gamma0022
Calcium/calmodulin-dependent protein kinase type II subunit delta0022
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0022
Activin receptor type-2B0022
Bone morphogenetic protein receptor type-20022
Protein-tyrosine kinase 60022
cGMP-dependent protein kinase 1 0022
Cyclin-dependent kinase 130022
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0022
Protein-tyrosine kinase 2-beta0022
Sodium channel protein type 5 subunit alpha0101
Maternal embryonic leucine zipper kinase0022
Structural maintenance of chromosomes protein 1A0022
Chromodomain-helicase-DNA-binding protein 40022
Peroxisomal acyl-coenzyme A oxidase 10022
Ephrin type-A receptor 70011
Delta(24)-sterol reductase0022
Ribosomal protein S6 kinase alpha-10022
Dual specificity testis-specific protein kinase 10022
Myosin light chain kinase, smooth muscle0022
Mitogen-activated protein kinase 110022
Serine/threonine-protein kinase STK110022
Serine/threonine-protein kinase N10022
Serine/threonine-protein kinase N20022
Mitogen-activated protein kinase 140022
Calcium/calmodulin-dependent protein kinase type IV0022
Mitogen-activated protein kinase kinase kinase 110022
Discoidin domain-containing receptor 20022
AP2-associated protein kinase 10022
Myosin light chain kinase 30022
Putative heat shock protein HSP 90-beta 20022
Serine/threonine-protein kinase MRCK alpha0022
Serine/threonine-protein kinase MRCK gamma0022
Acyl-CoA dehydrogenase family member 100022
Serine/threonine-protein kinase N30022
Serine/threonine-protein kinase ULK30022
Uncharacterized protein FLJ452520022
Acyl-CoA dehydrogenase family member 110022
Serine/threonine-protein kinase/endoribonuclease IRE20022
Serine/threonine-protein kinase MARK20022
ATP-dependent RNA helicase DHX300022
Serine/threonine-protein kinase TAO10022
STE20-related kinase adapter protein alpha0022
Myosin-140022
AarF domain-containing protein kinase 10022
ATP-dependent RNA helicase DDX420011
Mitogen-activated protein kinase kinase kinase kinase 30022
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B0011
Regulatory-associated protein of mTOR0202
Atypical kinase COQ8A, mitochondrial0022
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0022
Mitogen-activated protein kinase 150022
Serine/threonine-protein kinase Nek90022
Serine/threonine-protein kinase Nek70011
ATP-dependent RNA helicase DDX10022
Mitogen-activated protein kinase kinase kinase kinase 10022
Aurora kinase B0022
MAP/microtubule affinity-regulating kinase 40022
Serine/threonine-protein kinase Nek10022
PAS domain-containing serine/threonine-protein kinase0022
Calcium/calmodulin-dependent protein kinase kinase 20022
EKC/KEOPS complex subunit TP53RK0022
Dual specificity testis-specific protein kinase 20022
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0022
Mitogen-activated protein kinase kinase kinase 50022
Mitogen-activated protein kinase kinase kinase 30022
Eukaryotic translation initiation factor 2-alpha kinase 10022
Target of rapamycin complex subunit LST80202
Nucleolar GTP-binding protein 10022
Serine/threonine-protein kinase D20022
NUAK family SNF1-like kinase 20011
RNA cytidine acetyltransferase0022
Serine/threonine-protein kinase SIK20022
STE20-like serine/threonine-protein kinase 0022
Serine/threonine-protein kinase TAO30022
dCTP pyrophosphatase 10022
Dual specificity protein kinase CLK40022
Casein kinase I isoform gamma-10022
Phenylalanine--tRNA ligase beta subunit0022
BMP-2-inducible protein kinase0022
Obg-like ATPase 10022
Midasin0022
Interleukin-1 receptor-associated kinase 40022
Mitogen-activated protein kinase kinase kinase 200022
Cyclin-dependent kinase 120022
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130011
Serine/threonine-protein kinase 260022
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0022
Serine/threonine-protein kinase NLK0022
5'-AMP-activated protein kinase subunit gamma-20022
Serine/threonine-protein kinase TBK10022
Septin-90022
Potassium voltage-gated channel subfamily D member 30101
Ribosomal protein S6 kinase alpha-60022
TRAF2 and NCK-interacting protein kinase0022
Serine/threonine-protein kinase TAO20022
Long-chain-fatty-acid--CoA ligase 50011
RAC-gamma serine/threonine-protein kinase0022
Serine/threonine-protein kinase SIK30022
Mitogen-activated protein kinase kinase kinase 20022
Thyroid hormone receptor-associated protein 30022
Mitogen-activated protein kinase kinase kinase kinase 50022
Receptor-interacting serine/threonine-protein kinase 30022
Serine/threonine-protein kinase MRCK beta0022
Interleukin-1 receptor-associated kinase 30022
Casein kinase I isoform gamma-30022
Mitogen-activated protein kinase kinase kinase 40022
Chain A, Uracil Phosphoribosyltransferase0101
Skn7p0001
pregnane X receptor2002
Thrombopoietin1001
thyroid stimulating hormone receptor2002
estrogen receptor 2 (ER beta)9009
huntingtin isoform 23003
flap endonuclease 15005
serine/threonine-protein kinase mTOR isoform 11001
Vpr3003
Solute carrier family 22 member 80001
Amyloid-beta precursor protein1102
Thymidylate synthase0101
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
Peptidylglycine alpha-amidating monooxygenase0001
cytochrome P450 family 3 subfamily A polypeptide 47007
cytochrome P450 2D65005
Smad33003
Type-1A angiotensin II receptor 0101
Type-1B angiotensin II receptor0202
Type-2 angiotensin II receptor0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
5-hydroxytryptamine receptor 1A0101
Type-1 angiotensin II receptor0101
Chain E, Fibrin beta chain0101
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
Chain A, JmjC domain-containing histone demethylation protein 3A5005
T cell receptor, partial1001
luteinizing hormone receptor1001
integrase, partial0101
chaperonin-containing TCP-1 beta subunit homolog1001
lens epithelium-derived growth factor p750101
Caspase 6, apoptosis-related cysteine peptidase0001
TSHR protein1001
Apoptotic peptidase activating factor 10101
hypothetical protein, conserved2002
isocitrate dehydrogenase 1, partial2002
luciferase1001
bromodomain adjacent to zinc finger domain 2B3003
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a5005
serine-protein kinase ATM isoform a1001
neutrophil cytosol factor 10101
thyroid hormone receptor beta isoform a3003
caspase-9 isoform alpha precursor0101
pyruvate kinase PKM isoform a1001
caspase-3 isoform a preproprotein0101
protein AF-9 isoform a0002
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
replicative DNA helicase0001
recombinase A0011
POsterior Segregation0011
DNA repair protein RAD52 homolog isoform a0001
Glutathione reductase0101
Glutathione reductase, mitochondrial0102
Glycoprotein hormones alpha chain1001
Albumin0001
Dihydrolipoyl dehydrogenase, mitochondrial0102
Microtubule-associated protein tau0112
Alpha-1B adrenergic receptor0303
Amine oxidase [flavin-containing] A0101
Alpha-1D adrenergic receptor0303
Sodium-dependent noradrenaline transporter 0011
Cruzipain0101
Alpha-synuclein4105
Alpha-1A adrenergic receptor0303
Guanine nucleotide-binding protein G2002
TAR DNA-binding protein 433003
Thioredoxin reductase 1, cytoplasmic0102
Dihydrolipoyl dehydrogenase 0102
Zinc finger protein mex-50011
phosphoglycerate kinase3003
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)3003
Nuclear receptor subfamily 1 group I member 20033
Glucocorticoid receptor06213
Glycine receptor subunit alpha-10606
Androgen receptor0303
Glycine receptor subunit beta0606
Glycine receptor subunit alpha-20606
Glycine receptor subunit alpha-30606
Nuclear receptor subfamily 1 group I member 20011
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
lethal factor (plasmid)1001
UDP-glucuronosyltransferase 1A90001
Glutamate receptor 10101
Glutamate receptor 30101
Glutamate receptor 40101
Inosine-5'-monophosphate dehydrogenase 1 0202
UDP-glucuronosyltransferase 1A1 0001
Sodium-dependent serotonin transporter0202
Peroxisome proliferator-activated receptor gamma0011
Inosine-5'-monophosphate dehydrogenase0102
UDP-glucuronosyltransferase 1A70001
UDP-glucuronosyltransferase 1A100001
UDP-glucuronosyltransferase 1A80001
WRN1001
Valosin-containing protein0101
regulator of G-protein signaling 42002
lysosomal alpha-glucosidase preproprotein1001
microphthalmia-associated transcription factor isoform 90101
importin subunit beta-1 isoform 11001
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
eukaryotic translation initiation factor 4 gamma 1 isoform 40101
serine/threonine-protein kinase PLK11001
snurportin-11001
eukaryotic translation initiation factor 4E isoform 10101
histone acetyltransferase KAT2A isoform 11001
Rap guanine nucleotide exchange factor 31001
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
Serum paraoxonase/arylesterase 10101
interferon gamma precursor0001
Somatostatin receptor type 10101
Somatostatin receptor type 20101
Somatostatin receptor type 40101
Somatostatin receptor type 30101
Somatostatin receptor type 50101
15-lipoxygenase, partial1001
GALC protein1001
cytochrome P450 2C19 precursor2002
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Histamine H2 receptor1001
luciferase0001
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Cytochrome P450 2C9 0303
Glutamine synthetase0011
Histamine H1 receptor0011
Prostaglandin G/H synthase 20101
Nociceptin receptor0011
Cytochrome P450 2J20202
Estrogen receptor beta0202
Tyrosine-protein kinase JAK20011
Cyclin-dependent kinase-like 50011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Eukaryotic translation initiation factor 4E0011
ATP-dependent translocase ABCB10101
Cytochrome P450 3A40202
Peptidyl-prolyl cis-trans isomerase FKBP1A0101
Serine/threonine-protein kinase receptor R30011
Peptidyl-prolyl cis-trans isomerase FKBP1A0426
Peptidyl-prolyl cis-trans isomerase FKBP1B0022
Protein kinase C zeta type0011
Cyclin-dependent kinase 180011
Tyrosine-protein kinase Mer0011
Peptidyl-prolyl cis-trans isomerase FKBP50202
Uncharacterized aarF domain-containing protein kinase 50011
Programmed cell death protein 40011
MAP kinase-activated protein kinase 50011
Misshapen-like kinase 10011
Calcium/calmodulin-dependent protein kinase type 1G0011
Serine/threonine-protein kinase mTOR 0101
Isoleucine--tRNA ligase, mitochondrial0011
Broad substrate specificity ATP-binding cassette transporter ABCG20202
Serine/threonine-protein kinase ICK0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0011
Serine/threonine-protein kinase 240011
Solute carrier organic anion transporter family member 1B10202
Squalene monooxygenase 0001
Beta-lactamase 0101
Beta-lactamase 0101
Beta-lactamase 0101
Beta-lactamase 0101
Beta-lactamase 0101
Beta-lactamase0101
Beta-lactamase0101
Beta-lactamase0101
Beta-lactamase SHV-10101
Replicase polyprotein 1ab0101
Beta-lactamase OXA-10101
5-hydroxytryptamine receptor 1A0101
Beta-lactamase0101
Metallo-beta-lactamase type 20101
Angiotensin-converting enzyme0101
Beta-lactamase TEM0202
Beta-lactamase 0101
Beta-lactamase 0101
nonstructural protein 10101
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
UDP-glucuronosyltransferase 2B70001
Cytochrome P450 3A50101
UDP-glucuronosyltransferase 1A40001
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Splicing factor 3B subunit 30101
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
heat shock protein HSP 90-alpha isoform 20101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Dihydroxyacetone phosphate acyltransferase0001
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
Tetracycline resistance protein, class B0001
Muscarinic acetylcholine receptor M20101
72 kDa type IV collagenase0101
Stromelysin-10101
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
Multidrug transporter MdfA0101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
Neutrophil collagenase0101
Collagenase 30101
Cannabinoid receptor 10101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Integrase 0101
Solute carrier family 22 member 80001
Solute carrier family 22 member 110001
Solute carrier family 22 member 70001
cytochrome P450 2D6 isoform 11001
Alpha-2A adrenergic receptor0303
Cytochrome P450 2D60101
Alpha-2B adrenergic receptor0202
Alpha-2C adrenergic receptor0202
Disintegrin and metalloproteinase domain-containing protein 171001
Sigma non-opioid intracellular receptor 10202
Albumin0011
Alpha-2B adrenergic receptor0101
Alpha-2C adrenergic receptor0101
Alpha-2A adrenergic receptor0101
D-alanyl-D-alanine dipeptidase0101
Transporter0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]