Rhinitis, Atrophic

A chronic inflammation in which the NASAL MUCOSA gradually changes from a functional to a non-functional lining without mucociliary clearance. It is often accompanied by degradation of the bony TURBINATES, and the foul-smelling mucus which forms a greenish crust (ozena).

Synonym
Rhinitis, Atrophic

Excerpt	Reference
"Porcine infectious atrophic rhinitis is a disease of swine which ought to be of considerable interest to rhinologists."	( Duberstein, LE; Hessler, JR, 1978)
"Atrophic rhinitis is a disease which manifests itself mainly by anosmia due to dryness and atrophy of the nasal mucosa."	( Yang, J; Zhang, Q, 1999)
"Progressive atrophic rhinitis is an upper respiratory tract disease of pigs caused by toxigenic strains of the bacterium Pasteurella multocida."	( Hamilton, TD; Hayes, CM; Jones, PH; Jordan, RW; Patel, D; Roe, JM; Williams, NA, 2003)
"Atrophic rhinitis is a chronic, debilitating and recalcitrant disease of the nasal cavities that is prevalent in several parts of the world."	( Dutt, SN; Kameswaran, M, 2005)
"Atrophic rhinitis is a chronic disease of the nasal mucosa."	( Bailie, N; Garcia, GJ; Kimbell, JS; Martins, DA, 2007)
"Ozena, or atrophic rhinitis, is a chronic nasal process seen in Africa, India, and the Middle East."	( Alpern, JD; Boyer, H; Schmidt, D; Stauffer, WM; Yelenich-Huss, MJ, 2016)
"Primary atrophic rhinitis is a disease of the nose and of paranasalsinuses characterized by a progressive loss of function of nasal and paranasal mucosa caused by a gradual destruction of ciliary mucosalepithelium with atrophy of serous-mucous glands and loss of bonestructures."	( Cocuzza, SG; Guerra, G; Lombardo, N; Marcuccio, G; Motta, G; Testa, D, 2021)

Excerpt	Reference
"Sulphadimidine is used to treat atrophic rhinitis in medicated feeds which do not benefit the animal but are the cause of persistent sulphonamide residues in feed mills and husbandry."	( Jager, LP; Vroomen, LH, 1990)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	207 (76.10)	23.3326
1990's	33 (12.13)	12.5806
2000's	19 (6.99)	18.1394
2010's	11 (4.04)	28.8240
2020's	2 (0.74)	9.53

Drug	Relationship Strength	Studies	Trials
acetic acid	low	3	0
ammonium hydroxide	medium	5	1
citric acid, anhydrous	low	1	0
glycerol	low	4	0
methanol	low	1	0
inositol	low	1	0
niacin	low	6	0
pyridoxine	low	1	0
sulfur dioxide	low	1	0
toluene	low	1	0
menthol	low	1	0
mercaptoethanol	medium	1	1
ciprofloxacin	medium	3	1
clioquinol	low	2	0
clonidine	low	1	0
erythrosine	low	1	0
furazolidone	low	1	0
gentamicin	low	3	0
guaifenesin	low	6	0
lidocaine	low	1	0
imipramine	low	1	0
isoniazid	low	1	0
oxymetazoline	low	1	0
procaine	low	7	0
saccharin	medium	1	1
sulfamethazine	low	6	0
sulfamonomethoxine	low	1	0
sulfaphenazole	low	1	0
sulfathiazole	low	1	0
trimethoprim	low	1	0
reserpine	low	5	0
penicillin g	low	1	0
chloramphenicol	low	6	0
glutamine	low	1	0
carbostyril	low	1	0
fluocinolone acetonide	low	1	0
chlorquinaldol	low	1	0
acetylene	low	1	0
phencyclidine	low	10	0
isoprene	low	1	0
acrylic acid	low	1	0
pantothenic acid	low	6	0
quinoxalines	low	1	0
pyronine	low	1	0
furan	low	1	0
framycetin	low	2	0
acridines	low	2	0
azulene	low	1	0
limestone	low	3	0
gentian violet	low	1	0
erythromycin	low	1	0
vancomycin	low	1	0
d-alpha tocopherol	low	5	0
spectinomycin	low	1	0
betamethasone valerate	low	1	0
sulfadoxine	low	1	0
streptomycin	low	15	0
carbonates	low	3	0
dihydrostreptomycin sulfate	low	3	0
tantalum	low	2	0
technetium	low	1	0
titanium	low	1	0
chromium	low	1	0
tricalcium phosphate	low	2	0
potassium dichromate	low	1	0
ozone	low	1	0
trolamine salicylate	low	1	0
chrysotile	low	1	0
titanium dioxide	low	1	0
cromolyn sodium	low	1	0
di-2-ethylhexyl sebacate	low	1	0
phenyl acetate	low	1	0
amoxicillin	low	1	0
10-carboxymethyl-9-acridanone	low	1	0
dolomite	low	3	0
cephalosporin c	low	1	0
enrofloxacin	low	1	0
fibrinogen	low	1	0
cortisone	low	1	0
trimethoprim, sulfamethoxazole drug combination	medium	2	1
retinol	low	5	0
mycophenolic acid	low	1	0
zithromax	low	1	0
diethylstilbestrol	low	1	0
arsphenamine	low	1	0
riboflavin	low	1	0
lincomycin	low	1	0
ovalbumin	low	3	0
alpha-chymotrypsin	low	1	0
17-ketosteroids	low	1	0
vitamin d 2	low	1	0
cholecalciferol	low	1	0
clavulanic acid	low	1	0
phenylephrine hydrochloride	low	92	0
aluminum	low	2	0
nitrofurazone	low	2	0
phosphorus	low	10	0
cefquinome	low	1	0
cefotaxime	low	1	0
amoxicillin-potassium clavulanate combination	low	1	0
dextrothyroxine	low	1	0
indocyanine green	low	1	0
acid phosphatase	low	2	0
nad	low	1	0
phosphatidylcholines	low	2	0
chlorophyll a	low	1	0
chitosan	low	2	0
lincospectin	low	1	0
mesna	medium	1	1
cardiovascular agents	low	1	0
glycolipids	low	1	0
methylcellulose	low	1	0
ascorbic acid	low	1	0
tetracycline	low	4	0
chlortetracycline	low	4	0
oxytetracycline, anhydrous	low	9	0
orabase	low	1	0
muramidase	low	2	0
rifampin	medium	3	2
carbadox	low	3	0
alcian blue	low	1	0

Protein Targets (967)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, Putative fructose-1,6-bisphosphate aldolase	5	0	0	5
Chain A, Ferritin light chain	8	0	0	8
acid sphingomyelinase	4	0	0	4
thioredoxin reductase	16	0	0	16
hypoxia-inducible factor 1 alpha subunit	8	0	0	8
SMAD family member 2	13	0	0	13
SMAD family member 3	13	0	0	13
TDP1 protein	38	0	0	38
GLI family zinc finger 3	27	0	0	27
AR protein	41	0	0	41
estrogen receptor 2 (ER beta)	15	0	0	15
nuclear receptor subfamily 1, group I, member 3	22	0	0	22
progesterone receptor	15	0	0	15
glucocorticoid receptor [Homo sapiens]	29	0	0	29
retinoic acid nuclear receptor alpha variant 1	27	0	0	27
retinoid X nuclear receptor alpha	25	0	0	25
farnesoid X nuclear receptor	17	0	0	17
estrogen nuclear receptor alpha	46	0	0	46
G	11	0	0	11
glucocerebrosidase	4	0	0	4
peroxisome proliferator-activated receptor delta	20	0	0	20
peroxisome proliferator activated receptor gamma	24	0	0	24
vitamin D (1,25- dihydroxyvitamin D3) receptor	22	0	0	22
alpha-galactosidase	2	0	0	2
euchromatic histone-lysine N-methyltransferase 2	31	0	0	31
activating transcription factor 6	17	0	0	17
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	15	0	0	15
v-jun sarcoma virus 17 oncogene homolog (avian)	13	0	0	13
Stimulator of interferon genes protein	0	0	1	1
chromobox protein homolog 1	15	0	0	15
thyroid hormone receptor beta isoform 2	28	0	0	28
heat shock protein beta-1	12	0	0	12
importin subunit beta-1 isoform 1	9	0	0	9
flap endonuclease 1	10	0	0	10
snurportin-1	9	0	0	9
nuclear factor erythroid 2-related factor 2 isoform 1	27	0	0	27
GTP-binding nuclear protein Ran isoform 1	3	0	0	3
geminin	32	0	0	32
peripheral myelin protein 22	12	0	0	12
Trypsin	0	0	0	1
Interferon beta	12	0	0	12
HLA class I histocompatibility antigen, B alpha chain	11	0	0	11
Cellular tumor antigen p53	27	0	0	27
TAR DNA-binding protein 43	12	0	0	12
Stimulator of interferon genes protein	0	0	1	1
Inositol hexakisphosphate kinase 1	11	0	0	11
cytochrome P450 2C9, partial	11	0	0	11
Free fatty acid receptor 3	0	0	1	1
Free fatty acid receptor 2	0	1	1	2
Tyrosine-protein kinase Lck	0	0	1	1
Tyrosine-protein kinase Fyn	0	2	1	3
Fibrinogen C domain-containing protein 1	0	1	0	1
Microtubule-associated protein tau	16	0	0	17
Smad3	9	0	0	9
aldehyde dehydrogenase 1 family, member A1	27	0	0	27
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	9	0	0	9
DNA polymerase iota isoform a (long)	17	0	0	17
DNA topoisomerase 2-alpha	0	1	0	5
Acetylcholinesterase	0	4	0	4
lamin isoform A-delta10	27	0	0	27
Choline O-acetyltransferase	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	19	0	0	19
Chain A, Beta-lactamase	10	0	0	10
Chain A, 2-oxoglutarate Oxygenase	16	0	0	16
Beta-lactamase	0	1	0	3
Beta-lactamase	0	1	0	4
Beta-lactamase	0	0	0	3
Beta-lactamase	0	1	0	4
apical membrane antigen 1, AMA1	5	0	0	5
Beta-lactamase	0	0	0	3
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	8	0	0	8
DNA polymerase eta isoform 1	4	0	0	4
urokinase-type plasminogen activator precursor	9	0	0	9
plasminogen precursor	9	0	0	9
urokinase plasminogen activator surface receptor precursor	9	0	0	9
DNA polymerase kappa isoform 1	9	0	0	9
ATP-binding cassette sub-family C member 3	0	16	0	16
Multidrug resistance-associated protein 4	0	16	0	16
Bile salt export pump	0	7	0	7
Bile salt export pump	0	32	0	32
Beta-lactamase SHV-1	0	1	0	4
Beta-lactamase SHV-1	0	2	0	5
Cytochrome P450 2C9	0	8	1	9
Beta-lactamase	0	1	0	4
Kappa-type opioid receptor	0	0	0	3
Solute carrier family 15 member 1	0	3	0	3
Solute carrier family 15 member 1	0	1	0	1
Cytochrome P450 2J2	0	5	0	5
B2 metallo-beta-lactamase	0	0	0	3
Solute carrier family 15 member 2	0	3	0	3
Beta-lactamase	0	1	0	4
Beta-lactamase	0	1	0	4
Solute carrier family 15 member 2	0	3	0	3
Beta-lactamase	0	1	0	4
Beta-lactamase	0	0	0	3
Canalicular multispecific organic anion transporter 1	0	16	0	16
Chain A, Hyaluronidase, phage associated	0	1	0	1
acetylcholinesterase	13	0	0	13
RAR-related orphan receptor gamma	31	0	0	31
thioredoxin glutathione reductase	8	0	0	8
cytochrome P450 family 3 subfamily A polypeptide 4	18	0	0	18
estrogen-related nuclear receptor alpha	28	0	0	28
IDH1	10	0	0	10
nuclear factor erythroid 2-related factor 2 isoform 2	6	0	0	6
lethal(3)malignant brain tumor-like protein 1 isoform I	4	0	0	4
lethal factor (plasmid)	12	0	0	12
Polyphenol oxidase 2	0	3	0	3
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	1	0	1
Alpha-2B adrenergic receptor	0	10	2	12
Spike glycoprotein	11	0	0	11
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
pregnane X nuclear receptor	21	0	0	21
cytochrome P450 2D6	14	0	0	14
aryl hydrocarbon receptor	16	0	0	16
thyroid stimulating hormone receptor	14	0	0	14
Histone H2A.x	13	0	0	13
Voltage-dependent calcium channel gamma-2 subunit	11	0	0	11
Glutamate receptor 2	11	1	0	12
GALC protein	4	0	0	4
thyrotropin-releasing hormone receptor	6	0	0	6
Bloom syndrome protein isoform 1	9	0	0	9
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Muscarinic acetylcholine receptor M2	0	5	2	8
Muscarinic acetylcholine receptor M4	0	6	2	9
Muscarinic acetylcholine receptor M1	0	2	2	6
Muscarinic acetylcholine receptor M3	0	2	2	5
Muscarinic acetylcholine receptor M4	0	2	1	4
Muscarinic acetylcholine receptor M5	0	3	1	5
Muscarinic acetylcholine receptor M5	0	6	2	9
Neuronal acetylcholine receptor subunit alpha-4	3	1	0	4
Muscarinic acetylcholine receptor M2	0	2	1	4
Muscarinic acetylcholine receptor M1	0	6	2	9
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	3	1	0	4
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Muscarinic acetylcholine receptor M1	0	1	2	4
Muscarinic acetylcholine receptor M3	0	6	2	9
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Delta-type opioid receptor	0	2	0	4
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	0	1	1
Muscarinic acetylcholine receptor	0	2	0	2
Muscarinic acetylcholine receptor M3	0	0	2	5
Muscarinic acetylcholine receptor M2	0	0	1	5
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
USP1 protein, partial	13	0	0	13
streptokinase A precursor	0	0	6	6
Estrogen receptor	0	0	1	1
Estrogen receptor beta	0	0	1	1
Luciferase	10	0	0	10
ATPase family AAA domain-containing protein 5	7	0	0	7
Ataxin-2	10	0	0	10
Carbonic anhydrase 1	0	6	0	9
Carbonic anhydrase 2	0	6	0	10
Carbonic anhydrase 4	0	5	0	7
Carbonic anhydrase	0	2	0	3
Carbonic anhydrase 15	0	2	0	3
Chain A, serum paraoxonase	0	1	0	1
nuclear receptor ROR-gamma isoform 1	9	0	0	9
Carbonic anhydrase 12	0	2	0	4
Carbonic anhydrase 3	0	2	0	4
Neutrophil cytosol factor 1	0	1	0	1
Carbonic anhydrase 6	0	2	0	4
Carbonic anhydrase 5A, mitochondrial	0	4	0	6
Carbonic anhydrase 7	0	2	0	4
Carbonic anhydrase 9	0	4	0	6
Carbonic anhydrase 13	0	1	0	2
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
Carbonic anhydrase 14	0	2	0	4
Carbonic anhydrase 5B, mitochondrial	0	3	0	4
Beta-lactamase	0	0	0	2
Beta-lactamase	0	1	0	3
Beta-lactamase	0	2	0	3
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase type 2	0	0	0	2
Metallo-beta-lactamase VIM-11	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	1	0	3
Metallo-beta-lactamase VIM-19	0	0	0	2
Beta-lactamase	0	1	0	3
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	2	0	3
Solute carrier family 22 member 6	0	2	0	2
Albumin	0	0	5	5
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Metallo-beta-lactamase VIM-13	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	1	0	3
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase Toho-1	0	0	0	2
Solute carrier family 22 member 6	0	1	0	1
Solute carrier family 22 member 7	0	1	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Metallo-b-lactamase	0	0	0	3
BlaVIM-1	0	0	0	2
Beta-lactamase	0	0	0	2
Solute carrier family 22 member 8	0	2	0	3
Beta-lactamase	0	1	0	3
Carbapenem-hydrolyzing beta-lactamase KPC	0	2	0	4
Histamine H3 receptor	0	1	0	2
Beta-lactamase class B VIM-2	0	0	0	3
Solute carrier family 22 member 11	0	1	0	2
Solute carrier family 22 member 8	0	2	0	3
Beta-lactamase VIM-1	0	0	0	2
Solute carrier family 22 member 7	0	1	0	2
GLS protein	12	0	0	12
interleukin 8	12	0	0	12
EWS/FLI fusion protein	9	0	0	9
Dihydroxyacetone phosphate acyltransferase	0	0	0	2
30S ribosomal protein S6	0	5	1	6
30S ribosomal protein S7	0	5	1	6
50S ribosomal protein L15	0	5	1	6
Cytochrome P450 3A4	0	6	0	7
50S ribosomal protein L10	0	5	1	6
50S ribosomal protein L11	0	5	1	6
50S ribosomal protein L7/L12	0	5	1	6
50S ribosomal protein L19	0	5	1	6
50S ribosomal protein L1	0	5	1	6
50S ribosomal protein L20	0	5	1	6
50S ribosomal protein L27	0	5	1	6
50S ribosomal protein L28	0	5	1	6
50S ribosomal protein L29	0	5	1	6
50S ribosomal protein L31	0	5	1	6
50S ribosomal protein L31 type B	0	5	1	6
50S ribosomal protein L32	0	5	1	6
50S ribosomal protein L33	0	5	1	6
50S ribosomal protein L34	0	5	1	6
50S ribosomal protein L35	0	5	1	6
50S ribosomal protein L36	0	5	1	6
30S ribosomal protein S10	0	5	1	6
30S ribosomal protein S11	0	5	1	6
30S ribosomal protein S12	0	5	1	6
30S ribosomal protein S13	0	5	1	6
30S ribosomal protein S16	0	5	1	6
30S ribosomal protein S18	0	5	1	6
30S ribosomal protein S19	0	5	1	6
30S ribosomal protein S20	0	5	1	6
30S ribosomal protein S2	0	5	1	6
30S ribosomal protein S3	0	5	1	6
30S ribosomal protein S4	0	5	1	6
30S ribosomal protein S5	0	5	1	6
30S ribosomal protein S8	0	5	1	6
30S ribosomal protein S9	0	5	1	6
50S ribosomal protein L13	0	5	1	6
50S ribosomal protein L14	0	5	1	6
50S ribosomal protein L16	0	5	1	6
50S ribosomal protein L23	0	5	1	6
30S ribosomal protein S15	0	5	1	6
50S ribosomal protein L17	0	5	1	6
50S ribosomal protein L21	0	5	1	6
50S ribosomal protein L30	0	5	1	6
50S ribosomal protein L6	0	5	1	6
30S ribosomal protein S14	0	5	1	6
30S ribosomal protein S17	0	5	1	6
30S ribosomal protein S1	0	5	1	6
50S ribosomal protein L18	0	5	1	6
50S ribosomal protein L2	0	5	1	6
50S ribosomal protein L3	0	5	1	6
50S ribosomal protein L24	0	5	1	6
50S ribosomal protein L4	0	5	1	6
50S ribosomal protein L22	0	5	1	6
50S ribosomal protein L5	0	5	1	6
30S ribosomal protein S21	0	5	1	6
50S ribosomal protein L25	0	5	1	6
50S ribosomal protein L36 2	0	5	1	6
Methionine--tRNA ligase, mitochondrial	0	0	1	1
Nrf2	1	0	0	1
glp-1 receptor, partial	10	0	0	10
67.9K protein	10	0	0	10
LAP4	0	0	2	2
RPL19A	0	0	1	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	15	0	0	15
Vpr	3	0	0	3
DNA dC->dU-editing enzyme APOBEC-3F isoform a	4	0	0	4
Glycoprotein hormones alpha chain	2	0	0	2
Botulinum neurotoxin type A	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
P2Y purinoceptor 12	0	2	0	2
Protein-arginine deiminase type-4	0	7	0	7
Chain A, HADH2 protein	12	0	0	12
Chain B, HADH2 protein	12	0	0	12
Chain A, Cruzipain	8	0	0	8
15-lipoxygenase, partial	9	0	0	9
vitamin D3 receptor isoform VDRA	12	0	0	12
thyroid hormone receptor beta isoform a	13	0	0	13
survival motor neuron protein isoform d	8	0	0	8
cytochrome P450 3A4 isoform 1	18	0	0	18
Gamma-aminobutyric acid receptor subunit pi	18	1	0	19
60 kDa chaperonin	0	5	0	5
60 kDa heat shock protein, mitochondrial	0	7	0	7
Vitamin D3 receptor	0	1	1	5
Gamma-aminobutyric acid receptor subunit beta-1	18	1	0	19
Gamma-aminobutyric acid receptor subunit delta	18	1	0	19
Gamma-aminobutyric acid receptor subunit gamma-2	18	1	0	19
Gamma-aminobutyric acid receptor subunit alpha-5	18	1	0	19
Gamma-aminobutyric acid receptor subunit alpha-3	18	1	0	19
Glycine receptor subunit alpha-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-1	18	1	0	19
Gamma-aminobutyric acid receptor subunit alpha-2	18	1	0	19
Gamma-aminobutyric acid receptor subunit alpha-4	18	1	0	19
Gamma-aminobutyric acid receptor subunit gamma-3	18	1	0	19
Gamma-aminobutyric acid receptor subunit alpha-6	18	1	0	19
Vitamin D3 receptor	0	0	1	1
Nuclear receptor ROR-gamma	10	0	0	10
10 kDa heat shock protein, mitochondrial	0	7	0	7
Gamma-aminobutyric acid receptor subunit alpha-1	18	1	0	19
Gamma-aminobutyric acid receptor subunit beta-3	18	1	0	19
Gamma-aminobutyric acid receptor subunit beta-2	18	1	0	19
Thiosulfate sulfurtransferase	0	7	0	7
60 kDa chaperonin	0	7	0	7
10 kDa chaperonin	0	7	0	7
GABA theta subunit	18	1	0	19
Gamma-aminobutyric acid receptor subunit epsilon	18	1	0	19
cytochrome P450 2C9 precursor	4	0	0	4
Cytochrome P450 1A2	0	2	0	3
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	2	0	4
DNA gyrase subunit B	0	2	0	4
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	1	0	2
Cytochrome P450 2D6	0	6	0	6
DNA gyrase subunit A	0	1	0	2
Cytochrome P450 2C19	0	3	0	4
Multidrug resistance protein MdtK	0	0	1	1
Histamine H2 receptor	8	1	1	10
DNA gyrase subunit B	0	3	0	3
DNA gyrase subunit A	0	3	0	3
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	5
Potassium voltage-gated channel subfamily H member 2	0	6	0	7
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Integrase	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	10	0	0	10
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
Beta-lactamase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
3-dehydroquinate dehydratase	0	0	1	1
ATP-citrate synthase	0	0	0	1
Ribonuclease T	0	0	0	1
Cell death-related nuclease 4	0	0	0	1
3-dehydroquinate dehydratase	0	0	1	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	2
Neutrophil elastase	0	1	0	1
Beta-lactamase OXA-1	0	1	0	1
Cytochrome P450 2B6	0	2	1	3
Beta-lactamase TEM	0	3	0	5
Beta-lactamase	0	1	0	1
Class D beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	12	0	0	12
mu opioid receptor, partial	0	0	1	1
90-kda heat shock protein beta HSP90 beta, partial	0	2	0	2
phosphopantetheinyl transferase	8	0	0	8
ATAD5 protein, partial	7	0	0	7
Fumarate hydratase	6	0	0	6
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	8	0	0	8
regulator of G-protein signaling 4	10	0	0	10
nonstructural protein 1	5	0	0	5
polyprotein	6	0	0	6
bromodomain adjacent to zinc finger domain 2B	9	0	0	9
MEP2	0	0	1	1
cellular tumor antigen p53 isoform a	6	0	0	6
polyunsaturated fatty acid lipoxygenase ALOX12	3	0	0	3
delta-type opioid receptor	0	1	1	2
kappa-type opioid receptor isoform 1	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	5	0	0	5
potassium voltage-gated channel subfamily H member 2 isoform d	11	0	0	11
huntingtin isoform 2	2	0	0	2
mitogen-activated protein kinase 1	10	0	0	10
nuclear factor NF-kappa-B p105 subunit isoform 1	4	0	0	4
ubiquitin carboxyl-terminal hydrolase 2 isoform a	8	0	0	8
heat shock protein HSP 90-alpha isoform 2	0	2	0	3
Histone deacetylase 3	0	1	0	1
Amyloid-beta precursor protein	0	4	0	4
Integrin beta-3	5	0	0	5
Integrin alpha-IIb	5	0	0	5
Spike glycoprotein	0	1	0	1
Alpha-1B adrenergic receptor	0	12	2	14
Catechol O-methyltransferase	0	1	0	1
Alpha-1D adrenergic receptor	0	9	2	11
Alpha-synuclein	3	4	0	7
Alpha-1A adrenergic receptor	0	13	3	16
Histone deacetylase 4	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	5	0	0	5
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Histone deacetylase 1	0	1	0	1
Beta-galactosidase	0	0	1	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Histone deacetylase 8	0	1	0	1
Carbonic anhydrase 13	0	0	0	2
Histone deacetylase 6	0	1	0	1
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
heat shock protein 90, putative	0	0	0	1
Beta-1 adrenergic receptor	0	0	1	1
arylsulfatase A	5	0	0	5
Alpha-1B adrenergic receptor	0	0	1	1
cytochrome P450 2D6 isoform 1	5	0	0	5
cytochrome P450 2C19 precursor	5	0	0	5
muscarinic acetylcholine receptor M1	9	0	0	9
Membrane primary amine oxidase	0	1	0	1
Solute carrier family 22 member 1	0	4	0	7
5-hydroxytryptamine receptor 3A	0	0	1	1
Solute carrier family 22 member 3	0	4	0	5
5-hydroxytryptamine receptor 1A	0	2	0	2
Alpha-2A adrenergic receptor	0	11	3	14
Alpha-1A adrenergic receptor	0	2	1	3
Alpha-2C adrenergic receptor	0	10	1	11
D	0	3	0	3
D(3) dopamine receptor	0	4	0	4
5-hydroxytryptamine receptor 1A	0	7	1	8
Alpha-2B adrenergic receptor	0	8	2	10
Amine oxidase [flavin-containing] A	0	1	0	1
Alpha-2C adrenergic receptor	0	8	2	10
Alpha-2A adrenergic receptor	0	8	2	10
Alpha-1D adrenergic receptor	0	10	2	12
D(1B) dopamine receptor	0	3	0	3
Amine oxidase [flavin-containing] B	0	1	0	1
5-hydroxytryptamine receptor 1B	0	7	1	8
Adenosine receptor A2b	0	0	1	1
Adenosine receptor A2a	0	0	1	2
Alpha-2B adrenergic receptor	0	2	0	3
D(4) dopamine receptor	0	3	0	3
Alpha-1A adrenergic receptor	0	3	2	5
Alpha-1B adrenergic receptor	0	3	2	5
5-hydroxytryptamine receptor 7	0	3	0	3
D(2) dopamine receptor	0	3	0	3
Mu-type opioid receptor	0	3	1	4
Inositol monophosphatase 1	5	0	0	5
Alpha-2C adrenergic receptor	0	2	0	3
Alpha-2A adrenergic receptor	0	2	0	3
Alpha-2A adrenergic receptor	0	2	0	2
Nischarin	0	2	0	2
Solute carrier family 22 member 1	0	4	0	5
Multidrug and toxin extrusion protein 1	0	6	0	6
Nischarin	0	2	0	2
endonuclease IV	5	0	0	5
dopamine D1 receptor	2	0	0	2
pregnane X receptor	4	0	0	4
peripheral myelin protein 22 isoform 1	5	0	0	5
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
M-phase phosphoprotein 8	3	0	0	3
Glucocorticoid receptor	0	6	0	6
Sex hormone-binding globulin	0	0	2	2
Glycine receptor subunit alpha-1	0	6	0	6
Corticosteroid-binding globulin	0	2	0	2
Glycine receptor subunit beta	0	6	0	6
Glycine receptor subunit alpha-2	0	6	0	6
Glycine receptor subunit alpha-3	0	6	0	6
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Alkaline phosphatase, germ cell type	0	1	0	1
G protein-coupled receptor GPR35	0	0	1	1
G-protein coupled receptor 35	0	0	1	1
G-protein coupled receptor 35	0	0	1	1
Rap guanine nucleotide exchange factor 3	7	0	0	7
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
DNA polymerase beta	4	0	0	4
neuropeptide S receptor isoform A	4	0	0	4
thyroid stimulating hormone receptor	15	0	0	15
serine/threonine-protein kinase PLK1	4	0	0	4
histone-lysine N-methyltransferase 2A isoform 2 precursor	4	0	0	4
high affinity choline transporter 1 isoform a	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	3	0	0	3
Polyunsaturated fatty acid lipoxygenase ALOX15B	4	0	0	4
5-hydroxytryptamine receptor 4	0	4	0	4
Nuclear receptor subfamily 1 group I member 2	0	1	1	2
Estrogen receptor	0	4	2	7
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Beta-1 adrenergic receptor	0	2	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Adenosine receptor A3	0	4	0	4
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
D(2) dopamine receptor	0	8	0	8
Androgen receptor	0	5	0	5
Substance-K receptor	0	4	0	4
D(1A) dopamine receptor	0	4	0	4
Prostaglandin G/H synthase 1	0	1	0	1
Sodium-dependent noradrenaline transporter	0	4	1	5
Thromboxane-A synthase	0	1	0	1
5-hydroxytryptamine receptor 2A	0	9	0	9
5-hydroxytryptamine receptor 2C	0	5	0	5
Adenosine receptor A2a	0	4	0	4
Adenosine receptor A1	0	2	0	2
Sodium-dependent serotonin transporter	0	6	0	6
Mu-type opioid receptor	0	6	0	6
D(3) dopamine receptor	0	4	0	4
Vasopressin V1a receptor	0	2	0	2
Delta-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	4	0	4
5-hydroxytryptamine receptor 2B	0	8	0	8
5-hydroxytryptamine receptor 6	0	7	0	7
Estrogen-related receptor gamma	0	0	1	1
Sodium-dependent dopamine transporter	0	5	0	5
Aldehyde oxidase	0	1	0	1
UDP-glucose 4-epimerase	0	1	0	1
Mitogen-activated protein kinase 14	0	1	0	1
Estrogen receptor beta	0	3	2	6
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	4	0	4
Cysteinyl leukotriene receptor 1	0	2	0	2
serine-protein kinase ATM isoform a	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	2	2
fatty acid synthase	0	1	0	1
5-hydroxytryptamine receptor 2A	0	0	2	2
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
Motilin receptor	0	1	1	2
ATP-dependent translocase ABCB1	0	3	0	3
ATP-dependent translocase ABCB1	0	4	0	4
Chitinase B	0	1	0	1
ATP-dependent translocase ABCB1	0	3	0	3
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Cytochrome P450 1B1	0	2	0	2
Lanosterol 14-alpha demethylase	0	3	0	3
Chain A, ATP-DEPENDENT DNA HELICASE Q1	5	0	0	5
Genome polyprotein	0	1	1	2
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
hypothetical protein, conserved	3	0	0	3
eyes absent homolog 2 isoform a	3	0	0	3
histone acetyltransferase KAT2A isoform 1	7	0	0	7
relaxin receptor 1 isoform 1	1	0	0	1
Flavin reductase (NADPH)	0	0	1	1
ATP-dependent phosphofructokinase	7	0	0	7
large T antigen	0	1	0	1
NFKB1 protein, partial	3	0	0	3
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
Steryl-sulfatase	0	1	0	1
Aromatase	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 1	0	2	0	3
Mu-type opioid receptor	0	2	1	3
Solute carrier organic anion transporter family member 1A1	0	2	0	2
Ghrelin O-acyltransferase	0	1	0	1
nuclear receptor subfamily 1, group I, member 2	4	0	0	4
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
Lethal factor	0	1	0	1
Protein Rev	0	0	2	2
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
beta-amyloid peptide, A beta {N-terminal} [human, cerebrospinal fluid, conditioned medium of mixed-brain cell cultures, Peptide Partial, 33 aa]	1	0	0	1
caspase 7, apoptosis-related cysteine protease	4	0	0	4
alpha synuclein, partial	1	0	0	1
luciferase	1	0	0	1
caspase-3	4	0	0	4
Caspase-7	1	0	0	1
tumor necrosis factor	2	0	0	2
caspase-3	1	0	0	1
histone deacetylase 9 isoform 3	1	0	0	1
Epidermal growth factor receptor	0	1	0	1
Glutamate receptor ionotropic, kainate 1	1	0	0	1
Histamine H2 receptor	0	3	2	5
Glutamate receptor ionotropic, kainate 2	1	0	0	1
Glutamate receptor ionotropic, kainate 3	1	0	0	1
Fatty-acid amide hydrolase 1	1	0	0	1
Glutamate receptor ionotropic, kainate 4	1	0	0	1
Leukotriene B4 receptor 1	1	0	0	1
Glutamate receptor ionotropic, kainate 5	1	0	0	1
Leukotriene B4 receptor 2	1	0	0	1
Chain A, Glutamine Binding Protein	0	0	1	1
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	2
Amino acid transporter	0	1	0	1
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Solute carrier family 22 member 2	0	1	0	2
Plasma kallikrein	0	0	0	1
Macrophage migration inhibitory factor	0	3	0	3
Adenosine receptor A1	0	0	0	1
5-hydroxytryptamine receptor 1D	0	1	0	2
Histamine H1 receptor	0	1	2	3
Histamine H1 receptor	0	3	1	4
Metabotropic glutamate receptor 5	0	3	1	4
Histamine H1 receptor	0	4	2	6
Glutamate receptor ionotropic, NMDA 1	0	3	0	4
Carbonic anhydrase	0	1	0	3
Histamine H3 receptor	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	3	0	4
Glutamate receptor ionotropic, NMDA 2B	0	3	0	4
Glutamate receptor ionotropic, NMDA 2C	0	3	0	5
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	1	0	3
Glutamate receptor ionotropic, NMDA 2D	0	3	0	4
Carbonic anhydrase	0	0	0	2
Equilibrative nucleoside transporter 4	0	0	0	1
Glutamate receptor ionotropic, NMDA 3B	0	3	0	4
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carbonic anhydrase 4	0	0	0	1
Histamine H4 receptor	0	1	2	3
Carboxylic ester hydrolase	0	0	0	1
Solute carrier family 22 member 2	0	2	0	3
Glutamate receptor ionotropic, NMDA 3A	0	3	0	4
Histamine H3 receptor	0	1	2	3
Snq2p	0	0	0	1
D(1A) dopamine receptor	2	0	0	2
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Sodium-dependent noradrenaline transporter	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Major prion protein	0	0	1	1
Prostaglandin G/H synthase 1	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	2
5-hydroxytryptamine receptor 2A	0	4	0	4
Sphingomyelin phosphodiesterase	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	1	0	2
Sodium-dependent dopamine transporter	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	1	2
5-hydroxytryptamine receptor 1F	0	1	1	2
5-hydroxytryptamine receptor 2B	0	3	0	3
5-hydroxytryptamine receptor 6	0	1	0	1
Sodium-dependent serotonin transporter	0	5	0	5
5-hydroxytryptamine receptor 7	0	1	0	1
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	2	0	2
UDP-glucuronosyltransferase 1A3	0	0	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
D(1A) dopamine receptor	1	0	0	1
D(2) dopamine receptor	0	1	0	1
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Envelope glycoprotein	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Sodium channel protein type 5 subunit alpha	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	3	0	3
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Transporter	0	3	0	3
Sodium channel protein type 10 subunit alpha	0	1	0	1
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
Sodium/myo-inositol cotransporter 2	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Myeloperoxidase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
Cytochrome P450 2C8	0	2	0	2
Cytochrome P450 2A6	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
Pantothenate synthetase	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Endonuclease 8-like 1	0	1	0	1
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Serum paraoxonase/arylesterase 1	0	2	0	2
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Secreted chorismate mutase	0	1	0	1
Transient receptor potential cation channel subfamily M member 8	0	1	2	4
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Transient receptor potential cation channel subfamily M member 8	0	0	1	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	2	0	2
Glutamate receptor 1	0	1	0	1
Glutamate receptor 3	0	1	0	1
Glutamate receptor 4	0	1	0	1
Inosine-5'-monophosphate dehydrogenase 1	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	1	0	2
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A7	0	0	0	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
lysosomal alpha-glucosidase preproprotein	3	0	0	3
Cholesteryl ester transfer protein	0	1	0	1
D-amino-acid oxidase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
transcriptional regulator ERG isoform 3	3	0	0	3
Snake venom metalloproteinase BaP1	0	1	0	1
NAD(+) hydrolase SARM1	0	2	0	2
chaperonin GroEL	1	0	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 1B	0	1	0	1
WRN	2	0	0	2
Valosin-containing protein	0	1	0	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
muscleblind-like protein 1 isoform 1	2	0	0	2
phosphoglycerate kinase	1	0	0	1
Type II pantothenate kinase	0	0	0	1
Type III pantothenate kinase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	1	0	2
Beta-lactamase 1	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Guanine nucleotide-binding protein G	2	0	0	2
Beta-lactamase	0	0	0	1
Efflux transporter	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
Beta-lactamase	0	0	0	1
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Muscarinic acetylcholine receptor M4	0	0	1	2
Kappa-type opioid receptor	0	0	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Mu-type opioid receptor	0	0	0	1
Cholinesterase	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Muscarinic acetylcholine receptor M5	0	0	1	2
Sigma non-opioid intracellular receptor 1	0	1	0	1
beta-2 adrenergic receptor	1	0	0	1
Pyridoxal kinase	0	0	0	1
BRCA1	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
nonstructural protein 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
thyrotropin-releasing hormone receptor	1	0	0	1
ras-related protein Rab-9A	1	0	0	1
caspase-3 isoform a preproprotein	0	1	0	1
insulin-degrading enzyme isoform 1	0	0	1	1
tumor susceptibility gene 101 protein	1	0	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
Thrombopoietin	2	0	0	2
hemoglobin subunit beta	1	0	0	1
caspase-1 isoform alpha precursor	2	0	0	2
Quinolone resistance protein NorA	0	1	0	2
DNA topoisomerase 1	0	2	0	2
Chromaffin granule amine transporter	0	1	0	1
Caspase-7	2	0	0	2
Synaptic vesicular amine transporter	0	1	0	1
Synaptic vesicular amine transporter	0	2	1	3
Synaptic vesicular amine transporter	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
Chain H, Immunoglobulin Igg1 Heavy chain	0	0	1	1
Chain L, Immunoglobulin Igg1 Lambda Light Chain	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain C, DODECIN	0	0	1	1
Chain E, DODECIN	0	0	1	1
NPYLR7B	0	0	1	1
Riboflavin-binding protein	0	1	1	2
DNA-directed RNA polymerase subunit beta	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
NH(3)-dependent NAD(+) synthetase	0	2	0	2
Arylacetamide deacetylase	0	1	0	2
Caspase-1	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	2	0	3
Solute carrier organic anion transporter family member 1B1	0	2	0	3
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Cholinesterase	0	1	0	1
Delta-type opioid receptor	0	1	0	1
Taste receptor type 2 member 31	0	0	1	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
RmtA	0	1	0	1
Protein arginine N-methyltransferase 1	0	1	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Carbonic anhydrase	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	1	0	1
Cytochrome P450 2C18	0	1	0	1
UDP-glucuronosyltransferase 2B10	0	1	0	1
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
Dihydropteroate synthase	0	1	0	1
Transcriptional activator protein LasR	0	1	0	1
Endothelin-1 receptor	0	1	0	1
Endothelin-1 receptor	0	1	0	1
Protein arginine N-methyltransferase 6	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
Stromelysin-1	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Endolysin	0	0	1	1
Chain A, Dihydrofolate Reductase	0	0	1	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, dihydrofolate reductase (DHFR)	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase type 1	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase type 1 from Tn4003	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
ClpP	1	0	0	1
POsterior Segregation	0	0	1	1
Estrogen receptor beta	0	1	0	1
Estrogen receptor	0	1	0	1
M-phase inducer phosphatase 1	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Zinc finger protein mex-5	0	0	1	1
PPM1D protein	1	0	0	1
twin arginine protein translocation system - TatA protein	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (272)

Protein Targets (967)

Rhinitis, Atrophic

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (272)

Drugs Studied (140)

Protein Targets (967)