Page last updated: 2024-08-05 12:38:06

12alpha-hydroxy steroid

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ChEBI ID: 36846

Members (11)

MemberDefinitionRole
3,7,12-trihydroxycholestan-26-oic acidA steroid acid that is 5beta-cholestan-26-oic acid which is substituted by hydroxy groups as the 3alpha, 7alpha, and 12alpha positions.3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oic acid
3,7,12-trihydroxycoprostane5beta-cholestane-3alpha,7alpha,12alpha-triol
3,7,12-trihydroxycoprostanic acid3alpha,7alpha,12alpha-trihydroxy-5beta-cholestane-5-carboxylic acid
3,7,12,24-tetrahydroxycholestanoic acid3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oic acid
3alpha,12alpha-dihydroxy-4alpha-methylergosta-8,24(28)-dien-7,11-dione-26-oic acidA steroid acid that is ergosta-8,24(28)-dien-26-oic acid substituted by hydroxy groups at positions 3 and 12, a methyl group at position 4 and oxo groups at positions 7 and 11 (the 3alpha,4alpha,5alpha,12alpha stereoisomer). Isolated from Antrodia cinnamomea and Antrodia camphorata, it exhibits antineoplastic activity.zhankuic acid C
allocholic acidAn allo-bile acid that is 5alpha-cholan-24-oic acid bearing three alpha-hydroxy substituents at position 3, 7 and 12.allocholic acid
cholestane-3,7,12,26-tetrol5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol
cholic acidA bile acid that is 5beta-cholan-24-oic acid bearing three alpha-hydroxy substituents at position 3, 7 and 12.cholic acid
scymnol5beta-scymnol
tenuigeninSenegenin
ursocholic acidA bile acid that is 5beta-cholan-24-oic acid bearing three hydroxy substituents at positions 3alpha, 7beta and 12alpha.ursocholic acid

Research

Studies (2,025)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990508 (25.09)18.7374
1990's466 (23.01)18.2507
2000's409 (20.20)29.6817
2010's495 (24.44)24.3611
2020's147 (7.26)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials43 (2.01%)5.53%
Reviews33 (1.54%)6.00%
Case Studies32 (1.49%)4.05%
Observational0 (0.00%)0.25%
Other2,033 (94.96%)84.16%