Roles > EC 1.3.1.43 (arogenate dehydrogenase) inhibitor
Page last updated: 2024-08-05 15:28:06
EC 1.3.1.43 (arogenate dehydrogenase) inhibitor
An EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of arogenate dehydrogenase (EC 1.3.1.43).
ChEBI ID: 64416
Members (1)
Research
Studies (43,043)
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|
| pre-1990 | 12,108 (28.13) | 18.7374 |
| 1990's | 9,534 (22.15) | 18.2507 |
| 2000's | 12,285 (28.54) | 29.6817 |
| 2010's | 7,245 (16.83) | 24.3611 |
| 2020's | 1,871 (4.35) | 2.80 |
Study Types
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|
| Trials | 846 (1.91%) | 5.53% |
| Reviews | 1,754 (3.96%) | 6.00% |
| Case Studies | 680 (1.54%) | 4.05% |
| Observational | 23 (0.05%) | 0.25% |
| Other | 40,970 (92.54%) | 84.16% |
Protein Targets (38)
Potency Measurements
Inhibition Measurements
Activation Measurements
Other Measurements
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | KA | 0.0110 | 1 | 1 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | KA | 0.0110 | 1 | 2 |
| Carbonic anhydrase | Candida albicans SC5314 | KA | 46.1000 | 1 | 1 |
| Carbonic anhydrase | Methanosarcina thermophila | KA | 24.0000 | 1 | 1 |
| Carbonic anhydrase | Methanothermobacter thermautotrophicus str. Delta H | Ka | 10.5000 | 1 | 1 |
| Carbonic anhydrase | Saccharomyces cerevisiae S288C | Ka | 85.0000 | 2 | 2 |
| Carbonic anhydrase | Cryptococcus neoformans var. grubii | KA | 29.5000 | 1 | 1 |
| Carbonic anhydrase | Nakaseomyces glabratus CBS 138 | Ka | 9.5000 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | KA | 0.0200 | 11 | 11 |
| Carbonic anhydrase 12 | Homo sapiens (human) | KA | 25.8000 | 1 | 1 |
| Carbonic anhydrase 14 | Homo sapiens (human) | KA | 21.8000 | 1 | 1 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | KA | 8.9000 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ka | 0.0110 | 13 | 13 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ka | 34.1000 | 2 | 2 |
| Carbonic anhydrase 4 | Homo sapiens (human) | KA | 25.1000 | 2 | 2 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | KA | 2.4500 | 1 | 1 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | KA | 0.0440 | 1 | 1 |
| Carbonic anhydrase 6 | Homo sapiens (human) | KA | 9.3100 | 2 | 2 |
| Carbonic anhydrase 7 | Homo sapiens (human) | KA | 20.3000 | 1 | 1 |
| Carbonic anhydrase 9 | Homo sapiens (human) | KA | 25.3000 | 1 | 1 |
| Carbonic anhydrase-like protein, putative | Trypanosoma cruzi strain CL Brener | KA | 4.9200 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | KA | 20.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | KA | 20.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | KA | 20.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | KA | 20.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | KA | 20.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | KA | 20.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | KA | 20.3000 | 1 | 1 |
| Monocarboxylate transporter 10 | Rattus norvegicus (Norway rat) | Km | 2,590.0000 | 1 | 1 |
| Plasma kallikrein | Homo sapiens (human) | KA | 0.0440 | 1 | 1 |
| Polyphenol oxidase 2 | Agaricus bisporus | Km | 230.0000 | 2 | 2 |
| SLC16A10 protein | Homo sapiens (human) | Km | 636.3000 | 1 | 1 |
| Taste receptor type 2 member 14 | Homo sapiens (human) | Activity | 1,000.0000 | 1 | 1 |