Page last updated: 2024-09-28

Calciphylaxes

Condition of induced systemic hypersensitivity in which tissues respond to appropriate challenging agents with a sudden local calcification.

Synonyms(3)

Synonym
Calciphylaxis
Calciphylaxes
Idiopathic Calciphylaxis

Research Excerpts

Overview

ExcerptReference
"Calciphylaxis is a local tissue calcific reaction at the site of an injection of challenger substance given a critical time period after the oral administration of a sensitizer substance such as dihydrotachysterol (DHT), vitamin D or parathormone."( McClure, J; Miller, S; Vernon-Roberts, E, 1984)
"Calciphylaxis is a rare disease associated with hemodialysis or transplantation, high parathyroid hormone values, and increased serum calcium x phosphate (Ca x P) product."( Fine, A; Fleming, S; Leslie, W, 1995)
"Calciphylaxis is a rare and life-threatening complication that is estimated to occur in 1% of patients with ESRD each year."( Budisavljevic, MN; Cheek, D; Ploth, DW, 1996)
"Calciphylaxis is a rare late complication in patients with advanced, often end-stage renal failure."( Dannenberg, L; Göbel, U; Henschel, A; Ott, A; Schultz-Ehrenburg, U, 1999)
"Calciphylaxis is a rapidly developing, fatal process of vascular calcium deposition with prominent cutaneous manifestation."( Hanaoka, M; Higashihara, M; Kobayashi, Y; Matsuo, T; Nagaoka, T; Saegusa, N; Tamura, M; Tsukamoto, Y; Yokoyama, H, 2001)
"Calciphylaxis is a severe complication of chronic renal failure, confined almost exclusively to patients on dialysis therapy."( Cosio, FG; Middendorf, DF; Singh, I; Voroshilova, O; Wilmer, WA, 2001)
"Calciphylaxis is associated with a very high mortality."( Davis, CL; Gillen, D; Johnson, RJ; Mazhar, AR; Ryan, MJ; Stehman-Breen, CO; Stivelman, JC, 2001)
"Calciphylaxis is a rare disorder of small-vessel calcification and cutaneous infarction associated with chronic renal failure."( Kaur, JS; Pfeifer, EA; Riegert-Johnson, DL, 2001)
"Calciphylaxis is an uncommon but serious disease process that affects mainly patients with advanced renal failure."( Barrientos, A; Coronel, F; López-Bran, E; Marrón, B, 2001)
"Calciphylaxis is a rare complication in patients undergoing hemodialysis."( Friedman, SG, 2002)
"Calciphylaxis is an uncommon condition usually seen in patients with end-stage renal disease."( Jacobsohn, HA; Jacobsohn, KM; Jenkins, PG, 2002)
"Calciphylaxis is a rare syndrome developing predominantly in female patients suffering from end-stage renal disease (ESRD) with secondary hyperparathyroidism."( Graefe, T; Tittelbach, J; Wollina, U, 2001)
"Calciphylaxis is a rare and potentially fatal complication of end stage renal disease (ESRD) and secondary hyperparathyroidism associated with abnormal calcium metabolism."( Bliss, DE, 2002)
"Calciphylaxis is a relatively rare, but horribly disfiguring, skin condition that is most often associated with end-stage renal disease and long-term dialysis."( Beitz, JM, 2003)
"Calciphylaxis is a dreaded complication of renal failure characterized by nodular subcutaneous calcification and painful tissue necrosis often leading to ulceration, secondary infection, and high mortality rates."( Cicone, JS; Embert, CD; Petronis, JB; Spector, DA, 2004)
"Breast calciphylaxis is a rare disease clinically characterized by progressive tissular necrosis with secondary cutaneous ulceration and by vascular calcification and thrombosis."( Buxant, F; Jedwab, J; Noël, JC, 2004)
"Calciphylaxis is a condition with a generally poor prognosis about which relatively little is known."( Beus, KS; Stack, BC, 2004)
"Calciphylaxis is a small-vessel disease associated with renal failure."( Horishita, T; Minami, K; Ogata, J; Sata, T, 2004)
"Calciphylaxis is associated with medial arteriolar vascular calcification and results in ischemic subcutaneous necrosis with vulnerable skin ulcerations and high mortality."( Hayden, MR; Khanna, R; Kolb, L; Sowers, JR; Tyagi, SC, 2005)
"Calciphylaxis is a rare, but life-threatening complication of end-stage renal disease (ESRD) that has been reported mostly in adult patients."( Bloom, DA; Imam, AA; Kapur, G; Mattoo, TK; Valentini, RP, 2005)
"Calciphylaxis is a highly morbid syndrome of vascular calcification and skin necrosis, the pathophysiology of which remains largely elusive."( Line, BR; Norris, B; Vaysman, V, 2005)
"Calciphylaxis is a very uncommon and severe disease which mainly appears in patients with chronic renal insufficiency."( Gille, J; Kaufmann, R; Meissner, M, 2006)
"When calciphylaxis is complicated with advanced renal hyperparathyroidism (HPT), parathyroidectomy (PTX) should be performed promptly."( Hirakata, H; Iida, M; Maeda, H; Taniguchi, M; Tokumoto, M; Tsuruya, K; Yotsueda, H, 2007)
"Calciphylaxis is a relatively rare disorder associated with calcification of small- and medium-sized blood vessels, progressive ischemic skin necrosis, and ulcerations."( Amin, MB; Bosler, DS; Gulli, F; Malhotra, RK, 2007)
"Calciphylaxis is a rare condition affecting patients suffering from end-stage renal failure, characterised by cutaneous ischaemia and necrosis."( Bubtana, AJ; Hutchison, AJ; Mitra, S; Mohammed, IA; Sekar, V, 2008)
"Calciphylaxis is a rare, but potentially life-threatening condition usually observed in patients with end-stage chronic renal disease and characterized by small- and medium-sized blood vessel calcification leading to tissue ischemia."( Bonfigli, F; Giansante, C; Gottardi, C; Padovan, C; Trevisan, G; Ulessi, B, 2008)
"Calciphylaxis is a rare necrotizing calcifying arteriolopathy, with a poor prognosis, for which there is currently no effective treatment."( Allot, V; Bonnetblanc, JM; Durox, H; Labrousse, F; Pommepuy, I; Prey, S; Roux, C; Salem, A; Sparsa, A, 2009)
"Calciphylaxis is a rare, life-threatening cause of skin necrosis."( Hackett, BC; McAleer, MA; O'Donnell, BF; Powell, FC; Sheehan, G, 2009)
"Calciphylaxis is defined by the presence of calcium deposits within the wall of small and medium-sized vessels."( Daudén, E; Oñate, MJ, 2008)
"As the treatment of calciphylaxis is mainly empirical and controversial, we decided to administer cinacalcet with paricalcitol for the control of hyperparathyroidism and sodium thiosulfate to improve the calcification of the arterioles."( Agroyannis, B; Agroyannis, I; Gombou, A; Griveas, I; Kyritsis, I; Retsa, K, 2008)
"Calciphylaxis is a rare and debilitating vasculopathy predominantly seen in patients with renal failure."( Chan, MR; Hinshaw, M; Jaffery, JB; Yevzlin, AS, 2008)
"Calciphylaxis is a rare complication that occurs in 1% of patients with end-stage renal disease (ESRD) each year."( Almafragi, A; Dujardin, K; Vandorpe, J, 2009)
"Calciphylaxis is an infrequent but severe entity found in chronic dialysis patients."( Algranati, L; Enz, P; Galimberti, R; Garfi, L; Gelman, R; Giuseppe, LD; Kowalczuk, A; Lizarraga, A; Musso, CG; Vidal, F, 2009)
"Calciphylaxis is a rare, usually fatal vasculopathic disorder characterized by cutaneous ischemia and necrosis due to calcification of arterioles."( Banerjee, C; Holm, JR; Lahey, MJ; Stevens, SM; Woller, SC, 2010)
"Penile calciphylaxis is very rare but has a mortality rate of 69% within 6 months."( Djebali, D; Gini, MB; Ranade, A; Sandhu, G; Smith, S, 2012)
"Calciphylaxis is a rare complication of chronic renal failure mostly with poor prognosis."( Sulková, SD; Válek, M, 2010)
"Calciphylaxis is a severe "vascular ossification-calcification," associated with a very high mortality rate that involves arterial wall, venular wall, and nerves resulting in ischemia and necrosis of skin, subcutaneous fat, visceral organs, and skeletal muscles."( Di Raimondo, D; La Placa, S; Li Vecchi, M; Licata, G; Miceli, S; Milio, G; Pinto, A; Tuttolomondo, A, 2011)
"Calciphylaxis is a rare condition with dismal prognosis that affects patients with ESRD."( Landis, M; Moe, SM; Noureddine, L; Patel, N, 2011)
"Cutaneous calciphylaxis is a potentially fatal condition characterized by calcium deposition in dermal arterioles and the subsequent development of livedo reticularis, plaques, and extremely painful ulcers."( Amerio, P; Auriemma, M; Bonomini, M; Caponio, C; Carbone, A; Cupaiolo, A; De Simone, C; Di Liberato, L; Tulli, A, 2011)
"Calciphylaxis is a rare but life-threatening disease characterized by deposition of calcium within small and medium sized vessels, with subsequent thrombosis, cutaneous ischemia, and necrosis."( Barr, KL; Onofiok, E; Sivamani, RK, 2011)
"Calciphylaxis is a rare disease primarily affecting patients dependent on dialysis."( Heiro, M; Hohenthal, U; Koivuviita, N; Mäkelä, L; Manner, I; Metsärinne, K; Tertti, R, 2011)
"Calciphylaxis is a frequent entity in patients with chronic renal failure of diverse etiology."( Aliaga, LG; Barreira, JC, 2012)
"Calciphylaxis is a rare disorder characterized by painful skin necrosis and calcification of small vessels which is seen mainly in the dialysis population."( Naugler, W; Wichienkuer, P; Wusirika, R, 2011)
"Calciphylaxis is still an incompletely understood rare disease, which most often affects people on haemodialysis."( Brandenburg, VM; Ketteler, M; Kramann, R; Specht, P, 2012)
"Calciphylaxis is a rare and potentially life-threatening condition."( Merchant, W; Oliphant, T; Shareef, M; Smith, VM; Wilkinson, SM, 2012)
"Calciphylaxis is a life-threatening complication in patients with end-stage renal disease (ESRD)."( Auinger, M; König, M; Lhotta, K; Lingenhel, G; Rudnicki, M; Salmhofer, H; Schilcher, G; Vychytil, A; Wallner, M; Zitt, E, 2013)
"Calciphylaxis is a rare and life-threatening disease characterized by cutaneous necrosis and vascular calcification."( Arakaki, RY; Hoang, MP; Kroshinsky, D; Mochel, MC; Wang, G, 2013)
"Calciphylaxis is a relatively rare disease, observed mainly in patients on dialysis, associated with high mortality rates, and characterized by painful skin ulceration."( Hayashi, M, 2013)
"Calciphylaxis is an uncommon and often under diagnosed condition affecting patients undergoing chronic dialysis."( Burnie, R; Javaid, MM; Smail, S, 2013)
"Calciphylaxis is a rare life-threatening form of skin necrosis."( Brais, R; Deegan, P; Hafiji, J; Norris, P, 2013)
"Calciphylaxis is a metastatic calcification-induced vasculopathy that results in the occlusion of small blood vessels."( Castellanos, EH; Dahir, KM; McGirt, LY; Ning, MS, 2013)
"Calciphylaxis is a potentially fatal disorder of abnormal calcium deposition."( Bis, S; Kroshinsky, D; Nigwekar, SU; Sise, M; Smith, GP; Steele, D; Strazzula, L; Tsiaras, W, 2013)
"Calciphylaxis is a rare cutaneous disorder, characterized by vascular calcification and progressive skin necrosis, not yet described in cats."( Er, E; Reinacher, M; Thom, N, 2013)
"Calciphylaxis is a rare, yet life-threatening disease mainly occurring in dialysis patients."( Berr, F; Fend, F; Franzen, M; Hauser-Kronberger, C; Heemann, U; Hitzl, W; Koller, J; Kreymann, B; Salmhofer, H; Schmaderer, C, 2013)
"Calciphylaxis is a rare condition seen mostly in patients with chronic renal disease and secondary hyperparathyroidism who develop painful skin lesions and myopathy secondary to extensive small vessel calcification, which leads to tissue ischemia."( Motiwala, R; Sejdiu, F; Shin, S; Stavros, K; Zhou, L, 2014)
"Calciphylaxis is characterized by calcification and thrombosis of arteries resulting in ischemic necrosis of predominantly skin and subcutaneous tissue."( Asif, A; Goez-Gutierrez, E; Gonzalez-Suarez, M; Nayer, A; Rosenberg, AE; Salman, LH; Virmani, S, 2014)
"Calciphylaxis is a rare and life-threatening disorder associated with a mortality of 60-80%."( Borges, L; Cássio, I; Dias, E; Rosa, P, 2014)
"AbstractBackground:Calciphylaxis is a life-threatening condition traditionally observed in patients with end-stage renal disease."( Fernandes, C; Hanna, D; Maynard, B, 2014)
"Calciphylaxis is a rare and severe disease with an annual incidence of around 1 % in dialysis patients."( Aoun, A; Banydeen, R; Baubion, E; Derancourt, C; Djiconkpode, I; Dueymes, JM; Ekindi, N; Quist, D; Riaux, A; Sadreux, T; Ureña-Torres, P, 2014)
"Calciphylaxis is a rare cause of skin ulcerations and necrosis in patients with both normal renal and parathyroid function."( Arnault, JP; Chaby, G; Chatelain, D; Dadban, A; Dhaille, F; Dhillies, AS; Lok, C; Lombart, F; Lorriaux, A, 2015)
"Calciphylaxis is a complication of chronic kidney disease characterized by necrotic lesion in the skin."( Hooman, N; Jahangiri, F; Mehrazma, M; Naghshi-Zadiyan, R, 2015)
"Calciphylaxis is associated with a poor prognosis in dialysis patients, and its pathogenesis remains incompletely understood."( Bardsley, V; El-Damanawi, R; Fry, AC; Galloway, PA; Hiemstra, TF; Ojha, SK; Pritchard, NR, 2015)
"Calciphylaxis is dangerous by its fast progression into tissue necrosis, difficult healing process and a great risk of secondary infection which is the most common cause of death in this condition."( Blaštíková, J; Dvořáková, G; Souček, M; Svojanovský, J; Vyskočilová, M, 2015)
"Calciphylaxis is a rare disease in which the treatment is basically supportive."( Sarkis, E, 2015)
"Calciphylaxis is a rare but devastating condition that has continued to challenge the medical community since its early descriptions in the scientific literature many decades ago."( Goverman, J; Jackson, VA; Kamdar, MM; Kroshinsky, D; Malhotra, R; Nazarian, RM; Nigwekar, SU; Steele, DJ; Thadhani, RI, 2015)
"Calciphylaxis is a painful, debilitating, and premorbid condition, which presents as calcified vasculature and soft tissues."( Agarwal, S; Esmonde-White, K; Fagan, S; Goverman, J; Jumlongras, D; Levi, B; Lloyd, WR; Loder, S; Morris, MD; Nigwekar, SU; Olsen, BR, 2015)
"Calciphylaxis is characterized by abnormal calcification of vessels and skin; however, its aetiology and pathogenesis remain unclear."( Barrett, J; Carter, A; Nunley, J; Ortega-Loayza, AG, 2016)
"Calciphylaxis is defined as calcification of the media of small- and medium-sized blood vessels in the dermis and subcutaneous tissue."( Jiménez-Gallo, D; Linares-Barrios, M; Ossorio-García, L, 2015)
"Calciphylaxis is a syndrome of systemic calcification of the arteries leading to painful tissue necrosis and ulceration."( Biswas, A; Tremaine, R; Walsh, NM, 2016)
"Calciphylaxis is a small vessel vasculopathy, characterized by medial wall calcification that develops in a few patients with chronic renal failure."( Adedjouma, A; Arrestier, R; Audard, V; Bartolucci, P; Bentaarit, B; Boulahia, G; Colin, C; Deux, JF; Dudreuilh, C; Dufresne, R; Grimbert, P; Kofman, T; Lang, P; Leibler, C; Maitre, B; Matignon, M; Remy, P; Sahali, D; Tran Van Nhieu, J, 2016)
"Non-uremic calciphylaxis is a severe rare disorder characterized by ischemic necrosis."( Alsina, M; Colmenero, J; Guañabens, N; Monegal, A; Peris, P, 2016)
"Calciphylaxis is a rare disorder predominantly seen in patients with chronic kidney disease."( Bourgeois, P; De Haes, P, 2016)
"Calciphylaxis is associated with a high mortality rate."( Albright, RC; Bridges, AD; Claus, PL; Davis, MD; Dillon, JJ; El-Azhary, RA; El-Zoghby, ZM; Hickson, LJ; Kumar, R; McBane, RD; McCarthy, JT; McCarthy-Fruin, KA; McEvoy, MT; Patzelt, MT; Pittelkow, MR; Weaver, AL; Wetter, DA; Williams, AW, 2016)
"Warfarin-associated calciphylaxis is distinct from classic calciphylaxis in pathogenesis, course, and, particularly, outcome."( Bhutani, T; Fox, LP; Kornik, R; Mauro, T; Pincus, LB; Rosenblum, MD; Yu, WY, 2017)
"Calciphylaxis is a severe complication of advanced chronic kidney disease (CKD)."( Hong, D; Jun, M; Li, G; Peng, T; Wang, L; Wang, Y; Zhuo, L, 2018)
"Calciphylaxis is a rare skin disease with high morbidity and mortality that frequently affects patients with renal disease."( Dobry, AS; Ko, LN; Kroshinsky, D; Nigwekar, S; Sloan, JM; St John, J, 2018)
"Calciphylaxis is a devastating multifactorial disorder of the subcutaneous fat that is known to be associated with hypercoagulability."( Chen, TY; El-Azhary, RA; Lehman, JS; Lohse, CM, 2018)
"Calciphylaxis is a rare disease with a poor prognostic that mostly occurs in patients with renal failure."( Alves, C; Ernandez, T; Stoermann Chopard, C, 2018)
"Calciphylaxis is a rare disease characterized by calcification of small- to medium-sized blood vessels in the dermis and subcutaneous fat, resulting in cutaneous necrosis."( Bradauskaite, G; Chewaproug, D; Minimo, C; Nseir, V; Pedroza, M; Zaki, R, 2021)
"Calciphylaxis is a disease of dermal arteriolar calcification that results in necrosis."( Garza-Mayers, AC; Kroshinsky, D; Nigwekar, SU; Shah, R; Sykes, DB, 2018)
"Calciphylaxis is a rare, painful, and debilitating disorder of vascular calcification and skin necrosis that typically affects patients with advanced kidney disease."( Cipriani, NA; Moy, AP; Nazarian, RM; Nigwekar, SU; Williams, EA, 2019)
"Calciphylaxis is a rare and potentially fatal disease that affects the subcutaneous layer of the skin."( Riedhammer, MM; Truong, DH; Zinszer, K, 2019)
"Calciphylaxis is a rare but life-threatening condition, most commonly affecting patients with stage 4 or 5 chronic kidney disease."( Deen, J; Schaider, H, 2019)
"Calciphylaxis is an infrequent disease that almost exclusively affects patients with chronic kidney disease, although cases have been observed in patients without renal function impairment."( Alvarez, CL; Estifan Ksabji, J; Fernández Cañabate, S; Ortega Valin, L, 2018)
"Calciphylaxis is a syndrome of cutaneous ischaemic necrosis and ulceration due to arteriolar calcification with subsequent thrombosis, which rarely presents in patients without terminal kidney disease."( Minasyan, A; Sainz-Gaspar, L; Sánchez-Aguilar, MD; Suárez-Peñaranda, JM, 2019)
"Calciphylaxis is a complex dermatological lesion of micro vascular calcification that is typically presented as panniculitis with gangrenous painful lesions having uremic and non-uremic causes."( Kaklotar, JC; Patel, AD; Patel, DM; Patel, GR; Patel, MM; Patel, MV, 2019)
"Non-uremic calciphylaxis is a rare, life-threatening condition characterized clinically by cutaneous necrosis and histologically by calcium deposition in small vessel walls."( Cotter, D; Hinds, B; Kusari, A; Paravar, T, 2019)
"Calciphylaxis is an uncommon life-threatening systemic disease, mostly occurring in patients with chronic kidney disease and other risk factors."( Breznik, V; Burja, S; Ekart, R; Jovic, A; Miljkovic, J; Piko, N, 2019)
"Calciphylaxis is a life threatening complication in renal patients."( Hoyer, J; Kamalanabhaiah, S; Kortus-Goetze, B; Russ, P; Russwurm, M, 2019)
"Calciphylaxis is a cutaneous ischemic infarct caused by total occlusion of blood vessels initiated by vascular calcification."( Chang, JJ, 2019)
"Calciphylaxis is a disorder of cutaneous microvascular calcification and thrombosis leading to chronic, excruciatingly painful, progressive wounds with a high risk of sepsis and death."( Nigwekar, SU; Seethapathy, H, 2019)
"Calciphylaxis is a very complicated disease that usually presents in patients with end-stage renal disease (ESRD)."( Al-Talib, K; Zuhaili, B, 2019)
"Calciphylaxis is a rare disorder of poor prognosis that can lead to intense, painful lesions involving the skin and subcutaneous tissue."( Noureddine, L; Seethapathy, H, 2019)
"Calciphylaxis is a rare and severe disease that manifests with painful skin ulceration and necrosis."( Hamada, T; Honda, H; Iida, A; Kanazawa, N; Mima, Y; Miyazawa, N; Mizobuchi, M; Saito, T; Shikida, Y; Sugiyama, M; Suzuki, T; Wada, Y, 2020)
"Calciphylaxis is a rare condition usually seen in patients with end-stage renal disease."( Chinnadurai, R; Lowney, AC; Miller, M; Sinha, S, 2020)
"Calciphylaxis is a rare thrombotic vasculopathy characterized by high morbidity and mortality."( Baker, O; Blum, AE; Chakrala, T; Chand, S; Dobry, AS; François, J; Gabel, CK; Garza-Mayers, AC; Ko, LN; Kroshinsky, D; Nguyen, ED; Nigwekar, SU; Rrapi, R; Shah, R; St John, J, 2021)
"Calciphylaxis is a serious condition that often occurs in patients with end-stage renal failure undergoing hemodialysis, with potential comorbidities of hyperparathyroidism and chronic kidney disease (CKD)."( Ali, F; Friedman, BJ; Gordon Spratt, E; Matharu, T; Nagesh, RV, 2020)
"Calciphylaxis is a rare and severe condition, characterized by calcification and thrombosis of small vessels, mainly affecting the skin."( Hamich, S; Lagrange, B; Lavelle, O; Mazereeuw, M; Rakotoson, J; Sanchez, M; Tristani, H, 2020)
"Calciphylaxis is a rare, highly morbid pathological syndrome of vascular calcification and tissue necrosis."( Coe, S; Cole, W; Yoder, CM, 2020)
"Calciphylaxis is a small vessel vasculopathy causing subcutaneous ischemic necrosis."( Ghanavatian, S; James, DL; Sadolf, JS, 2021)
"Calciphylaxis is a rare but potentially fatal disease commonly occurred in dialysis patients."( Liu, B; Liu, H; Liu, Y; Tang, R; Xie, X; Yang, X; Zhang, X, 2021)
"Calciphylaxis is a rare life-threatening condition, with calcification of small and medium-sized vessels leading to skin necrosis."( Casadesus, D; Schnur, J; Sinawe, H; Yoham, AL, 2021)
"Calciphylaxis is a potencially disorder in patients with hyperphosphatemic familial tumoral calcinosis (HFTC)."( Gómez, C; Morales, P; Requena, S; Santos-Juanes, J, 2022)
"Calciphylaxis is a rare and devastating condition with important systemic ramifications."( Chand, S; Kroshinsky, D; Micheletti, R; Ortega-Loayza, AG; Pasieka, HB; Rick, J; Rrapi, R; Shinohara, MM; Strowd, L, 2022)
"Calciphylaxis is a life-threatening complication most often associated with chronic kidney disease that occurs as a result of the deposition of calcium in dermal and adipose microvasculature."( Aghagoli, G; Gallo Marin, B; Hu, SL; Massoud, CM; Robinson-Bostom, L, 2023)
"Calciphylaxis is a rare disease, predominantly in chronic kidney disease (CKD), characterized by high morbidity and mortality."( Jiao, Y; Liu, H; Ni, H; Sun, L; Xie, X; Zhang, X; Zhao, Y, 2023)
"Calciphylaxis is a rare disease with high mortality mainly involving patients with chronic kidney disease (CKD)."( Chitalia, V; Durant, O; Goverman, J; Kalim, S; Kramann, R; Krinsky, S; Kroshinsky, D; Malhotra, CK; Malhotra, R; Mengesha, B; Nazarian, RM; Nigwekar, SU; Portales-Castillo, I; Seethapathy, R; Wen, W, 2023)
"Calciphylaxis is a rare disease characterized by calcification of the middle layer of small arteries and arterioles, causing secondary cuta-neous ischemia."( Ana, T; Anamá, DP; Carolina, V; Denys, P; Guido, MC; Luis, M; María, D; Paula, E, 2023)

Context

ExcerptReference
"Calciphylaxis has been diagnosed after receiving anticoagulation with phenprocoumon after a single event of pulmonary embolism."( Alharbi, Z; Demir, E; Grieb, G; Pallua, N; Piatkowski, A; Simons, D; Tsolakidis, S, 2013)
"Cases of nonuremic calciphylaxis have also been reported, but data on this rare condition are mainly empirical."( Fernandes, C; Hanna, D; Maynard, B, 2014)
"Calciphylaxis has been reported to be encountered in different parts of the body."( Aldaoud, N; Aldulaijan, FA; Aleisa, N; Algheryafi, L; AlQattan, AS; Ghulam, WZ, 2021)
"Calciphylaxis has poor prognosis which often results in amputation and high mortality."( Li, X; Liu, H; Liu, Y; Ni, H; Yang, C; Zhang, X, 2021)

Treatment

ExcerptReference
"Early recognition and prompt treatment of calciphylaxis is vital for symptom relief, ulcer healing, and prevention of sepsis and death."( Bliss, DE, 2002)
"Bisphosphonates may be effective in treating calciphylaxis and arteriosclerosis obliterans by reducing the formation of ectopic calcification around blood vessels."( Hanafusa, T; Katayama, I; Nishimura, Y; Tani, M; Umegaki, N; Yamaguchi, Y, 2007)
"Evidence for the treatment of calciphylaxis with pharmacotherapeutic interventions is limited to case reports."( Raymond, CB; Wazny, LD, 2008)
"As the treatment of calciphylaxis is mainly empirical and controversial, we decided to administer cinacalcet with paricalcitol for the control of hyperparathyroidism and sodium thiosulfate to improve the calcification of the arterioles."( Agroyannis, B; Agroyannis, I; Gombou, A; Griveas, I; Kyritsis, I; Retsa, K, 2008)
"Sodium thiosulfate (STS) is used to treat calciphylaxis and cyanide poisoning, but can lead to a serious anion-gap acidosis."( Bachmann, LM; Boyd, JC; Bruns, DE; Haverstick, DM; Heady, TN; Scott, MG; Wendroth, SM, 2014)
"The key to successful treatment of calciphylaxis is fast diagnosing of the disease and appropriate treatment management."( Blaštíková, J; Dvořáková, G; Souček, M; Svojanovský, J; Vyskočilová, M, 2015)
"Knowledge of advancement in the treatment of calciphylaxis, which was previously a highly fatal disease, is important for physicians and other professionals from various medical fields."( Breznik, V; Burja, S; Ekart, R; Jovic, A; Miljkovic, J; Piko, N, 2019)
"The diagnosis and treatment of calciphylaxis presents significant challenges."( Nigwekar, SU; Seethapathy, H, 2019)
"Our experience suggests that the treatment of calciphylaxis requires timely and multi-angle intervention."( Lu, Y; Shen, L; Xu, D; Zhou, L, 2022)
"Sodium thiosulfate was used to treat penile calciphylaxis in 23."( Susantitaphong, P; Takkavatakarn, K; Wipattanakitcharoen, A, 2023)

Research

Studies (495)

TimeframeStudies, This Condition (%)All Conditions %
pre-1990133 (26.87)23.3326
1990's16 (3.23)12.5806
2000's104 (21.01)18.1394
2010's184 (37.17)28.8240
2020's58 (11.72)9.53
DrugIndicatedRelationship StrengthStudiesTrials
phosphoserine0low10
citric acid, anhydrous0low10
chlorine0low120
formaldehyde0low20
glyoxylic acid0low10
dalteparin0low20
histamine0low60
phytic acid0medium41
orotic acid0low10
phenol0low10
thiosulfates0medium1231
1-anilino-8-naphthalenesulfonate0low20
acetaminophen0low10
alendronate0medium21
amitriptyline0low10
aspirin0low10
azathioprine0low10
bupivacaine0low10
chlorpromazine0low10
etidronate0medium51
gabapentin0low10
hydrochlorothiazide0low10
hydroxyurea0low10
lidocaine0low10
isoproterenol0low10
ketamine0low20
methadone0low10
pamidronate0low80
pentoxifylline0low10
phenindione0low10
potassium iodide0low10
risedronic acid0medium11
thalidomide0low10
ticlopidine0low10
reserpine0low10
sorbitol0low20
alloxan0low10
hydroxyproline0low10
prednisone0low50
biguanides0low10
serine0low10
aspartic acid0low10
cyanides0low10
methyltestosterone0low10
edetic acid0low20
methoxamine0low10
threonine0low10
alizarin0low10
arginine0low10
taurocholic acid0low10
quinoxalines0low10
xanthenes0low10
calcium gluconate0low10
nandrolone0low10
limestone0low10
reticulin0low10
copper gluconate0low20
durapatite0low10
vancomycin0low10
d-alpha tocopherol0low20
pregnenolone carbonitrile0low10
vantocil0low10
lanthanum0low50
silver0low10
thorium0low10
cerium0low50
chromium0low90
gadolinium0low20
uranium0low10
hypochlorous acid0low10
ferric chloride0low10
calcium phosphate, dibasic, anhydrous0low20
calcium phosphate, monobasic, anhydrous0low20
tricalcium phosphate0low90
ferrous chloride0low10
sodium thiosulfate0medium1231
ozone0low10
trolamine salicylate0low20
clodronic acid0low10
ethionine0low20
levamisole0low10
iodine0low10
phenyl acetate0low80
triamcinolone0low50
1-carboxyglutamic acid0low10
raloxifene hydrochloride0low10
clopidogrel0low10
ibandronic acid0medium11
caloreen0low10
zoledronic acid0low20
fluindione0low10
fibrinogen0low10
mci 90380low10
p-methoxy-n-methylphenethylamine0low50
fluo-30low10
methotrexate0low10
cinacalcet0medium301
calcium pyrophosphate0low20
thiophosphoric acid0low10
lanthanum carbonate0low40
dabigatran0low10
elastin0low10
inositol 3-phosphate0low10
meropenem0low10
retinol0low10
cocaine0low10
clindamycin0low10
sodium thiocyanate0low10
potassium permanganate0low90
bromochloroacetic acid0low10
pyrophosphate0low10
tamoxifen0low20
phosphothreonine0low10
ovalbumin0low30
alizarin red s0low10
osteoprotegerin0low10
calcitriol0low60
vitamin k semiquinone radical0medium131
alprostadil0low40
vitamin d 20low140
cholecalciferol0low120
paricalcitol0low40
humulene0medium21
menaquinone 60low10
phenylephrine hydrochloride0low10
vitamin k 10low20
lead0low150
tin0low20
aluminum0low80
bismuth0low10
thallium0low10
indium0low10
gallium0low10
phosphorus0low240
pregabalin0low10
oxalates0low10
rivaroxaban0low10
apixaban0low50
losartan potassium0low20
dihydrotachysterol0low610
acid phosphatase0low10
citric acid, iron, sorbitol drug combination0low10
sodium pertechnetate tc 99m0low10
egg white0low40
cardiovascular agents0low10
colistin0low10
chondroitin0low10
ascorbic acid0low10
tetracycline0low30
minocycline0low10
salicylates0low10
acenocoumarol0low60
warfarin0low450
phenprocoumon0low30
tigecycline0low10
erdafitinib0low10
caseins0low10
sodium phytate0medium31
technetium tc 99m medronate0low30
viomycin0low10

Protein Targets (1,190)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain B, pheromone binding protein0011
Chain A, pheromone binding protein0011
Chain A, JmjC domain-containing histone demethylation protein 3A100010
Chain A, RNA-directed RNA polymerase NS50101
acid sphingomyelinase3003
thioredoxin reductase240024
USP1 protein, partial170017
TDP1 protein290029
vitamin D3 receptor isoform VDRA140014
importin subunit beta-1 isoform 15005
flap endonuclease 19009
serine/threonine-protein kinase PLK12002
snurportin-15005
peptidyl-prolyl cis-trans isomerase NIMA-interacting 16006
GTP-binding nuclear protein Ran isoform 13003
DNA polymerase eta isoform 16006
DNA polymerase iota isoform a (long)160016
urokinase-type plasminogen activator precursor4004
plasminogen precursor4004
urokinase plasminogen activator surface receptor precursor4004
geminin350035
DNA polymerase kappa isoform 19009
fibroblast growth factor 22 isoform 1 precursor0001
Mitogen-activated protein kinase 130101
Beta-lactamase0101
Transthyretin0112
Fatty acid-binding protein, intestinal0112
Fatty acid-binding protein, adipocyte0112
Cyclin-A20101
Cannabinoid receptor 10112
Cyclin-dependent kinase 20123
Choline O-acetyltransferase0101
Mitogen-activated protein kinase 120101
Guanine nucleotide-binding protein G5005
Fatty acid-binding protein 50011
Fatty acid-binding protein 50011
Mitogen-activated protein kinase 110101
Mitogen-activated protein kinase 140101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE180018
Luciferase9009
RAR-related orphan receptor gamma280028
retinoid X nuclear receptor alpha210021
G140014
peroxisome proliferator activated receptor gamma210021
euchromatic histone-lysine N-methyltransferase 2360036
thyroid stimulating hormone receptor150015
chromobox protein homolog 1250025
parathyroid hormone/parathyroid hormone-related peptide receptor precursor5005
muscleblind-like protein 1 isoform 17007
Interferon beta210021
HLA class I histocompatibility antigen, B alpha chain 140014
Inositol hexakisphosphate kinase 1140014
cytochrome P450 2C9, partial140014
ATAD5 protein, partial110011
GLS protein120012
Microtubule-associated protein tau190020
Smad39009
aldehyde dehydrogenase 1 family, member A1210021
thyroid stimulating hormone receptor120012
nuclear receptor subfamily 1, group I, member 3210021
progesterone receptor170017
EWS/FLI fusion protein220022
retinoic acid nuclear receptor alpha variant 1290029
estrogen-related nuclear receptor alpha300030
estrogen nuclear receptor alpha420042
aryl hydrocarbon receptor120012
thyroid hormone receptor beta isoform 2220022
peripheral myelin protein 22150015
cytochrome P450 3A4 isoform 1150015
Gamma-aminobutyric acid receptor subunit pi150015
ATP-binding cassette sub-family C member 3027027
Multidrug resistance-associated protein 4028031
Solute carrier family 22 member 60405
Carbonic anhydrase 120405
UDP-glucuronosyltransferase 1A90001
Bile salt export pump0708
Voltage-dependent calcium channel gamma-2 subunit140014
Bile salt export pump038039
Cytochrome P450 2B10001
Cytochrome P450 1A10001
Carbonic anhydrase 1013015
Carbonic anhydrase 2015120
Myoglobin0101
Cytochrome P450 1A10012
Cytochrome P450 1A20013
Prostaglandin G/H synthase 10303
Carbonic anhydrase 30304
Cytochrome P450 3A40518
Cytochrome P450 2D60617
Cytochrome P450 2C9 010011
Polyunsaturated fatty acid lipoxygenase ALOX150303
Gamma-aminobutyric acid receptor subunit beta-1150015
Sulfotransferase 1A1 0002
Gamma-aminobutyric acid receptor subunit delta150015
Gamma-aminobutyric acid receptor subunit gamma-2150015
UDP-glucuronosyltransferase 1-60001
Glutamate receptor 2150015
Gamma-aminobutyric acid receptor subunit alpha-5150015
Gamma-aminobutyric acid receptor subunit alpha-3150015
Arachidonate 5-lipoxygenase-activating protein0101
UDP-glucuronosyltransferase 1A1 0102
Carbonic anhydrase 409010
Prostaglandin G/H synthase 10404
Carbonic anhydrase 60405
Gamma-aminobutyric acid receptor subunit gamma-1150015
Gamma-aminobutyric acid receptor subunit alpha-2150015
Gamma-aminobutyric acid receptor subunit alpha-4150015
Gamma-aminobutyric acid receptor subunit gamma-3150015
Gamma-aminobutyric acid receptor subunit alpha-6150015
Carbonic anhydrase 5A, mitochondrial0607
Prostaglandin G/H synthase 20304
Carbonic anhydrase 70304
Nuclear receptor ROR-gamma100010
Cytochrome P450 2J20808
Gamma-aminobutyric acid receptor subunit alpha-1151016
Gamma-aminobutyric acid receptor subunit beta-3150015
Gamma-aminobutyric acid receptor subunit beta-2150015
Carbonic anhydrase 90709
GABA theta subunit150015
Canalicular multispecific organic anion transporter 1026026
Carbonic anhydrase 150506
Carbonic anhydrase 130304
Gamma-aminobutyric acid receptor subunit epsilon150015
Carbonic anhydrase 140405
Carbonic anhydrase 5B, mitochondrial0304
toxin B0001
Chain E, Purine nucleoside phosphorylase0101
Chain A, HADH2 protein110011
Chain B, HADH2 protein110011
Chain A, ATP-DEPENDENT DNA HELICASE Q15005
Chain A, Ferritin light chain130013
Thymidine kinase 0101
phosphopantetheinyl transferase180018
arylsulfatase A110011
activating transcription factor 6130013
Histone H2A.x150015
Bloom syndrome protein isoform 1150015
hemoglobin subunit beta3003
atrial natriuretic peptide receptor 1 precursor2002
ubiquitin carboxyl-terminal hydrolase 2 isoform a7007
lamin isoform A-delta10240024
Solute carrier family 22 member 1 05010
Purine nucleoside phosphorylase0101
Thymidine kinase, cytosolic0001
POU domain, class 2, transcription factor 20001
Disintegrin and metalloproteinase domain-containing protein 176006
Purine nucleoside phosphorylase0011
Solute carrier family 22 member 60003
Thymidine kinase 0101
Solute carrier family 22 member 80004
Thymidine kinase0101
Chain A, farnesyl pyrophosphate synthase0101
Geranylgeranyl pyrophosphate synthase0708
Farnesyl pyrophosphate synthase010010
Acetylcholinesterase0303
Hypoxanthine-guanine phosphoribosyltransferase0202
Farnesyl pyrophosphate synthase 0606
Farnesyl pyrophosphate synthase 0303
Chain A, 2-oxoglutarate Oxygenase110011
endonuclease IV4004
15-lipoxygenase, partial6006
WRN1001
AR protein330033
estrogen receptor 2 (ER beta)140014
cytochrome P450 family 3 subfamily A polypeptide 4180018
cytochrome P450 2D6150015
polyunsaturated fatty acid lipoxygenase ALOX123003
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 15005
nuclear factor erythroid 2-related factor 2 isoform 28009
potassium voltage-gated channel subfamily H member 2 isoform d8008
histone deacetylase 9 isoform 34004
mitogen-activated protein kinase 1120012
nuclear factor erythroid 2-related factor 2 isoform 1270027
tumor susceptibility gene 101 protein1001
dual specificity tyrosine-phosphorylation-regulated kinase 1A0001
Vpr3003
survival motor neuron protein isoform d110011
histone acetyltransferase KAT2A isoform 19009
kelch-like ECH-associated protein 10002
Polyunsaturated fatty acid lipoxygenase ALOX15B7007
Gag-Pol polyprotein0101
Cellular tumor antigen p53230023
Apoptosis regulator Bcl-20101
D(3) dopamine receptor0303
Glutamate receptor 11001
Glutamate receptor 31001
Glutamate receptor 41001
Amine oxidase [flavin-containing] A0303
Amine oxidase [flavin-containing] B0202
Histamine H2 receptor81212
Inositol monophosphatase 15005
Induced myeloid leukemia cell differentiation protein Mcl-10101
TAR DNA-binding protein 435005
Cytochrome P450 1B10202
RmtA0101
Reverse transcriptase/RNaseH 0101
Protein arginine N-methyltransferase 10101
phosphoglycerate kinase2002
Tyrosine-protein phosphatase non-receptor type 10101
Phosphoglycerate mutase 10101
Tyrosine-protein phosphatase 10101
Pyruvate kinase PKLR0101
Chain A, Putative fructose-1,6-bisphosphate aldolase4004
Chain A, Xcogt0011
Chain A, Xcogt0011
Chain A, Xcogt0011
glucocorticoid receptor [Homo sapiens]300030
Thromboxane-A synthase 0202
Prostaglandin E2 receptor EP3 subtype0202
Prostaglandin E2 receptor EP4 subtype0213
Prostaglandin E2 receptor EP1 subtype0202
Prostacyclin receptor0538
Nuclear receptor subfamily 4 group A member 20011
Solute carrier organic anion transporter family member 2A10003
Nuclear receptor subfamily 4 group A member 20011
Nuclear receptor subfamily 4 group A member 20011
Prostaglandin E2 receptor EP2 subtype0213
Solute carrier organic anion transporter family member 2A10002
Solute carrier organic anion transporter family member 2B10102
Solute carrier organic anion transporter family member 3A10001
NFKB1 protein, partial6006
cytochrome P450 2D6 isoform 14004
D(1A) dopamine receptor4004
atrial natriuretic peptide receptor 2 precursor2002
serine/threonine-protein kinase mTOR isoform 15005
muscarinic acetylcholine receptor M1100010
Voltage-dependent L-type calcium channel subunit alpha-1F0303
5-hydroxytryptamine receptor 40808
Albumin0033
High affinity nerve growth factor receptor0123
Aldo-keto reductase family 1 member B10808
Muscarinic acetylcholine receptor M20909
Muscarinic acetylcholine receptor M40808
Muscarinic acetylcholine receptor M10404
Muscarinic acetylcholine receptor M30202
Muscarinic acetylcholine receptor M40202
5-hydroxytryptamine receptor 2C0506
Muscarinic acetylcholine receptor M50202
Muscarinic acetylcholine receptor M50808
Alpha-2A adrenergic receptor013013
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M10808
Angiotensin-converting enzyme0808
D(2) dopamine receptor012013
5-hydroxytryptamine receptor 2A0505
Alpha-2B adrenergic receptor012113
Alpha-2C adrenergic receptor010010
5-hydroxytryptamine receptor 1A0909
Muscarinic acetylcholine receptor M30808
D(1A) dopamine receptor011012
D(1B) dopamine receptor0203
UDP-glucuronosyltransferase 1A40003
Sodium-dependent noradrenaline transporter 012113
Histamine H2 receptor09211
Alpha-1D adrenergic receptor010112
5-hydroxytryptamine receptor 2A011011
5-hydroxytryptamine receptor 2C0808
5-hydroxytryptamine receptor 1B0909
5-hydroxytryptamine receptor 1D0202
5-hydroxytryptamine receptor 1F0202
5-hydroxytryptamine receptor 2B0404
5-hydroxytryptamine receptor 60202
Histamine H1 receptor0314
Sodium-dependent serotonin transporter012012
5-hydroxytryptamine receptor 7 0303
5-hydroxytryptamine receptor 5A0202
5-hydroxytryptamine receptor 5B0202
Histamine H1 receptor0628
D(3) dopamine receptor012013
Sodium channel protein type 1 subunit alpha0202
Sodium channel protein type 4 subunit alpha0404
UDP-glucuronosyltransferase 1A30001
5-hydroxytryptamine receptor 3A0202
5-hydroxytryptamine receptor 2B0808
Alpha-1A adrenergic receptor012012
D(1A) dopamine receptor5005
5-hydroxytryptamine receptor 60808
5-hydroxytryptamine receptor 70303
Voltage-dependent N-type calcium channel subunit alpha-1B0101
Sodium channel protein type 7 subunit alpha0202
Voltage-dependent L-type calcium channel subunit alpha-1D 0303
Sodium-dependent dopamine transporter 012012
Potassium voltage-gated channel subfamily H member 2011011
Voltage-dependent L-type calcium channel subunit alpha-1S0303
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Sodium channel protein type 5 subunit alpha0303
Sodium channel protein type 9 subunit alpha0303
Sigma non-opioid intracellular receptor 10011
5-hydroxytryptamine receptor 4 0202
Nuclear receptor subfamily 3 group C member 3 0808
Sodium channel protein type 2 subunit alpha0202
Ataxin-2120012
Sigma non-opioid intracellular receptor 1012113
5-hydroxytryptamine receptor 3B0202
Sodium channel protein type 3 subunit alpha0303
Sodium channel protein type 11 subunit alpha0202
Sodium channel protein type 8 subunit alpha0202
Histamine H3 receptor0325
Sodium channel protein type 10 subunit alpha0202
Chain A, Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor)0101
Coagulation factor X0101
Prothrombin0617
Coagulation factor X0707
Trypsin-10303
Trypsin-20303
Trypsin-30303
Spike glycoprotein151218
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
alpha-galactosidase3003
cytochrome P450 2C19 precursor3003
lethal factor (plasmid)110011
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0001
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30101
ATP-dependent phosphofructokinase110011
Chain A, Hyaluronidase, phage associated0101
acetylcholinesterase110011
GLI family zinc finger 3250025
thioredoxin glutathione reductase100010
vitamin D (1,25- dihydroxyvitamin D3) receptor160016
IDH1120012
lethal(3)malignant brain tumor-like protein 1 isoform I2002
Polyphenol oxidase 20102
Pancreatic alpha-amylase0202
Albumin0102
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE130013
Metabotropic glutamate receptor 60011
Excitatory amino acid transporter 40101
Glutamate transporter homolog0011
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0101
5-hydroxytryptamine receptor 1D0002
Glutamate receptor ionotropic, NMDA 1 0517
Excitatory amino acid transporter 10101
Excitatory amino acid transporter 20101
Excitatory amino acid transporter 30101
Glutamate receptor ionotropic, NMDA 2A 0517
Glutamate receptor ionotropic, NMDA 2B0517
Glutamate receptor ionotropic, NMDA 2C0517
Metabotropic glutamate receptor 10011
Metabotropic glutamate receptor 20011
Carbonic anhydrase-like protein, putative0002
Glutamate receptor ionotropic, NMDA 2D0517
Glutamate receptor ionotropic, NMDA 3B0517
Carbonic anhydrase 40002
Glutamate receptor ionotropic, NMDA 3A0517
Chain A, Phospholipase A2 isoform 30011
GTP-binding protein (rab7)0011
ras protein, partial0011
interleukin 85005
hypothetical protein, conserved3003
glucocerebrosidase6006
peroxisome proliferator-activated receptor delta160016
Rac1 protein0011
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
Prostaglandin-H2 D-isomerase0101
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
Epidermal growth factor receptor0404
Fatty acid-binding protein, liver0202
Integrin beta-36107
Myeloperoxidase0101
Seed linoleate 13S-lipoxygenase-10101
Integrin alpha-IIb6107
Glutathione hydrolase 1 proenzyme0101
Adenosine receptor A10203
Adenosine receptor A2a0203
Substance-P receptor0101
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Ras-related protein Rab-2A0011
Prostaglandin G/H synthase 20202
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200303
Solute carrier family 22 member 60303
Sigma non-opioid intracellular receptor 10011
SMAD family member 2120012
Fumarate hydratase7007
SMAD family member 3120012
farnesoid X nuclear receptor150015
pregnane X nuclear receptor210021
polyprotein7007
P531001
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a130013
v-jun sarcoma virus 17 oncogene homolog (avian)140014
peripheral myelin protein 22 isoform 17007
cellular tumor antigen p53 isoform a7007
heat shock protein beta-1110011
M-phase phosphoprotein 86006
ATPase family AAA domain-containing protein 59009
Protein-arginine deiminase type-40606
Potassium channel subfamily K member 30202
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20314
Potassium channel subfamily K member 90101
Chain A, Vitamin D Nuclear Receptor0011
Chain A, Beta-lactamase9009
Vitamin D3 receptor0011
PPM1D protein6006
nuclear receptor ROR-gamma isoform 19009
Vitamin D-binding protein0011
Androgen receptor0303
Vitamin D3 receptor0239
Vitamin D3 receptor0113
Retinoic acid receptor RXR-alpha0011
Cytochrome P450 2C190404
Kappa-type opioid receptor0011
Vitamin D3 receptor0022
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0011
Vitamin D3 receptor0112
Transporter0101
Vitamin D3 receptor A0022
bromodomain adjacent to zinc finger domain 2B7007
lysosomal alpha-glucosidase preproprotein2002
histone-lysine N-methyltransferase 2A isoform 2 precursor4004
short transient receptor potential channel 6 isoform 10011
Toll-like receptor 40202
Solute carrier family 22 member 20204
Amyloid-beta precursor protein0505
Beta-2 adrenergic receptor0438
ATP-dependent translocase ABCB10719
Beta-1 adrenergic receptor0628
Neuronal acetylcholine receptor subunit alpha-42002
Neuronal acetylcholine receptor subunit beta-22002
Beta-3 adrenergic receptor0527
Potassium channel subfamily K member 100101
Multidrug and toxin extrusion protein 10303
Carbonic anhydrase0506
Proteasome subunit beta type-110001
Thrombopoietin2002
caspase 7, apoptosis-related cysteine protease6006
NADPH oxidase 10101
67.9K protein6006
Snq2p0001
caspase-36006
Adenylate cyclase type 1 0202
Caspase-74004
Spike glycoprotein0123
Replicase polyprotein 1ab0123
caspase-34004
ras-related protein Rab-9A2002
Proteasome subunit alpha type-70001
Transmembrane protease serine 20123
Glutamate receptor ionotropic, NMDA 2D0202
Transient receptor potential cation channel subfamily V member 10101
Glutamate receptor ionotropic, NMDA 3B0202
Albumin0145
Major prion protein0011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Receptor tyrosine-protein kinase erbB-20202
Major prion protein0011
Tyrosine-protein kinase Fyn0303
Procathepsin L0123
5-hydroxytryptamine receptor 1A0101
Replicase polyprotein 1a0123
Replicase polyprotein 1ab0123
Replicase polyprotein 1ab0123
Cys-loop ligand-gated ion channel0101
Calmodulin-10213
Replicase polyprotein 1ab0123
Alpha-1B adrenergic receptor011011
Sphingomyelin phosphodiesterase0101
D0303
Alpha-2B adrenergic receptor0606
D(2) dopamine receptor0101
Proteasome subunit beta type-10001
Substance-K receptor0606
D(4) dopamine receptor0607
Adenylate cyclase type 30202
Alpha-2C adrenergic receptor0606
Alpha-2A adrenergic receptor0606
Alpha-1D adrenergic receptor0707
Sodium-dependent dopamine transporter0505
D(1B) dopamine receptor0202
Proteasome subunit alpha type-10001
Proteasome subunit alpha type-20001
Proteasome subunit alpha type-30001
Proteasome subunit alpha type-40001
Adenylate cyclase type 20202
Adenylate cyclase type 40202
Proteasome subunit beta type-80001
Proteasome subunit beta type-90001
Proteasome subunit alpha type-50001
Proteasome subunit beta type-40001
Proteasome subunit beta type-60001
Proteasome subunit beta type-50001
Trypanothione reductase0202
D(4) dopamine receptor0202
Histamine H1 receptor0235
Melanocortin receptor 40404
Melanocortin receptor 50404
Pleiotropic ABC efflux transporter of multiple drugs0102
5-hydroxytryptamine receptor 70101
Mu-type opioid receptor011112
Adenylate cyclase type 80202
Proteasome subunit beta type-100001
Delta-type opioid receptor0606
Kappa-type opioid receptor0819
Melanocortin receptor 30404
Proteasome subunit beta type-30001
Proteasome subunit beta type-20001
Gastrin/cholecystokinin type B receptor0101
Proteasome subunit alpha type-60012
D(2) dopamine receptor0304
Calmodulin 0112
Aldehyde oxidase 10101
Adenylate cyclase type 60202
Adenylate cyclase type 50202
Glutamate receptor ionotropic, NMDA 10303
Aldehyde oxidase0202
Glutamate receptor ionotropic, NMDA 2A0303
Glutamate receptor ionotropic, NMDA 2B0303
Glutamate receptor ionotropic, NMDA 2C0202
Adenylyl cyclase 7 0202
Proteasome subunit alpha-type 80001
Glutamate receptor ionotropic, NMDA 3A0202
D0101
Proteasome subunit beta type-70001
Angiotensin-converting enzyme 2 0224
Chain A, Cruzipain4004
thyroid hormone receptor beta isoform a120012
60 kDa chaperonin0303
60 kDa heat shock protein, mitochondrial0404
Glycine receptor subunit alpha-10022
10 kDa heat shock protein, mitochondrial0404
Thiosulfate sulfurtransferase0404
60 kDa chaperonin 0404
10 kDa chaperonin 0404
PINK11001
Parkin1001
huntingtin isoform 24004
Extracellular calcium-sensing receptor0011
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
hepatocyte nuclear factor 4-alpha isoform 20101
perilipin-50101
perilipin-10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
Beta-lactamase0101
Proto-oncogene tyrosine-protein kinase Src0101
3-dehydroquinate dehydratase0011
ATP-citrate synthase 0001
Ribonuclease T0001
Cell death-related nuclease 40001
3-dehydroquinate dehydratase0011
Prolyl 4-hydroxylase0101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Type IV secretion-like conjugative transfer relaxase protein TraI 0202
72 kDa type IV collagenase0303
Stromelysin-10314
Matrix metalloproteinase-90303
Macrophage metalloelastase0101
nonstructural protein 14004
Cytochrome P450 2C80202
Cytochrome P450 2B60505
Liver carboxylesterase 10002
Rap guanine nucleotide exchange factor 41001
P2Y purinoceptor 120202
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Gamma-aminobutyric acid receptor subunit pi0202
Gamma-aminobutyric acid receptor subunit delta0202
Fatty acid-binding protein, heart0101
Muscarinic acetylcholine receptor M20101
Tryptophan 5-hydroxylase 10101
Gamma-aminobutyric acid receptor subunit alpha-10213
Gamma-aminobutyric acid receptor subunit beta-10202
Gamma-aminobutyric acid receptor subunit gamma-20213
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0303
Gamma-aminobutyric acid receptor subunit beta-30202
Gamma-aminobutyric acid receptor subunit alpha-50202
Sodium-dependent serotonin transporter0304
Gamma-aminobutyric acid receptor subunit alpha-30202
Lysosomal Pro-X carboxypeptidase0101
Gamma-aminobutyric acid receptor subunit alpha-20202
Gamma-aminobutyric acid receptor subunit beta-20213
Gamma-aminobutyric acid receptor subunit alpha-40202
Gamma-aminobutyric acid receptor subunit epsilon0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0303
Leukotriene B4 receptor 11102
Gamma-aminobutyric acid receptor subunit alpha-60202
Sodium-dependent dopamine transporter0202
Gamma-aminobutyric acid receptor subunit gamma-10202
Gamma-aminobutyric acid receptor subunit gamma-30202
Leukotriene B4 receptor 21102
Gamma-aminobutyric acid receptor subunit theta0202
Transporter0303
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a9009
Rap guanine nucleotide exchange factor 37007
Glutathione S-transferase P0101
Alpha-tocopherol transfer protein0011
Plasminogen0202
Coagulation factor XII0202
Tissue-type plasminogen activator0202
Vitamin K-dependent protein C0101
Serine protease hepsin0101
Ribosyldihydronicotinamide dehydrogenase [quinone]0202
Multidrug and toxin extrusion protein 20101
regulator of G-protein signaling 48008
prostaglandin E2 receptor EP2 subtype1001
Solute carrier organic anion transporter family member 1A50002
Prostaglandin E2 receptor EP1 subtype0224
Prostaglandin E2 receptor EP4 subtype0213
Prostaglandin F2-alpha receptor0011
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP3 subtype0314
Prostaglandin E2 receptor EP2 subtype0224
Solute carrier family 22 member 70001
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier family 22 member 70001
Solute carrier family 22 member 110003
Solute carrier organic anion transporter family member 1B20002
Solute carrier family 22 member 70002
hypoxia-inducible factor 1 alpha subunit6006
Eyes absent homolog 20101
Angiotensin-converting enzyme 0101
Metallo-beta-lactamase VIM-130102
Beta-lactamase 0101
Beta-lactamase 0101
Beta-lactamase VIM-1 0102
Fibroblast growth factor receptor 10101
Fibroblast growth factor receptor 20101
Fibroblast growth factor receptor 40102
Fibroblast growth factor receptor 30101
Vascular endothelial growth factor receptor 20101
Receptor-type tyrosine-protein kinase FLT30101
Voltage-dependent calcium channel subunit alpha-2/delta-10202
apical membrane antigen 1, AMA13003
nuclear receptor subfamily 1, group I, member 23003
Multidrug resistance-associated protein 1 0002
Canalicular multispecific organic anion transporter 10103
beta-amyloid peptide, A beta {N-terminal} [human, cerebrospinal fluid, conditioned medium of mixed-brain cell cultures, Peptide Partial, 33 aa]1001
pregnane X receptor6006
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
alpha synuclein, partial1001
luciferase2002
thyrotropin-releasing hormone receptor2002
tumor necrosis factor1001
nuclear factor NF-kappa-B p105 subunit isoform 13003
Adenosine receptor A30404
Androgen receptor0909
Glutamate receptor ionotropic, kainate 11001
Adenosine receptor A2a0404
Glutamate receptor ionotropic, kainate 21001
Glutamate receptor ionotropic, kainate 31001
Fatty-acid amide hydrolase 11001
Glutamate receptor ionotropic, kainate 41001
Glutamate receptor ionotropic, kainate 51001
4-hydroxy-tetrahydrodipicolinate synthase0101
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Protein (female-specific Histamine Binding Protein 2)0011
aryl hydrocarbon receptor nuclear translocator0001
GALC protein2002
transforming acidic coiled-coil-containing protein 30001
Solute carrier family 22 member 30103
Plasma kallikrein0001
Macrophage migration inhibitory factor0202
Metabotropic glutamate receptor 50112
Carbonic anhydrase0002
Histamine H3 receptor0101
Histamine N-methyltransferase 0101
Glutaminyl-peptide cyclotransferase0101
Carbonic anhydrase 0103
Carbonic anhydrase0002
Carbonic anhydrase0103
Solute carrier family 22 member 10203
Carbonic anhydrase 0002
Equilibrative nucleoside transporter 40001
Carbonic anhydrase 130102
Histamine H4 receptor0123
Histamine H4 receptor0123
Histamine H4 receptor 0101
Histamine H4 receptor0123
Histamine H3 receptor0102
Carboxylic ester hydrolase 0001
Solute carrier family 22 member 20102
Carbonic anhydrase 0202
Hsf1 protein0011
Carbonic anhydrase 0101
cytochrome P450 2C9 precursor1001
Delta-type opioid receptor0101
Delta-type opioid receptor0202
Mu-type opioid receptor0303
Mu-type opioid receptor0101
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0101
Delta carbonic anhydrase0101
Neutral amino acid transporter A0202
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0202
Proton-coupled amino acid transporter 10202
Amino acid transporter0202
Urease subunit alpha0101
Ribonucleoside-diphosphate reductase large subunit0101
Urease subunit beta0101
Prostacyclin receptor0112
Prostaglandin D2 receptor0011
glp-1 receptor, partial7007
NPYLR7B0011
Beta-1 adrenergic receptor 0012
beta-2 adrenergic receptor2002
hexokinase-4 isoform 11001
glucokinase regulatory protein1001
Beta-2 adrenergic receptor0213
Beta-1 adrenergic receptor0214
Beta-2 adrenergic receptor0011
Beta-adrenergic receptor kinase 10011
Beta-3 adrenergic receptor0011
Beta-3 adrenergic receptor0112
Vasopressin V1a receptor0011
Beta-1 adrenergic receptor0112
Alpha-1A adrenergic receptor0012
Alpha-1B adrenergic receptor0012
Beta-2 adrenergic receptor0101
Taste receptor type 2 member 380011
Taste receptor type 2 member 390011
Taste receptor type 2 member 400011
Taste receptor type 2 member 410011
Taste receptor type 2 member 430011
Taste receptor type 2 member 310011
Taste receptor type 2 member 450011
Taste receptor type 2 member 460011
Taste receptor type 2 member 300011
Taste receptor type 2 member 190011
Taste receptor type 2 member 200011
Taste receptor type 2 member 500011
Taste receptor type 2 member 600011
Oxytocin receptor0011
Beta-2 adrenergic receptor 0112
Taste receptor type 2 member 420011
Beta-2 adrenergic receptor0022
Taste receptor type 2 member 160011
Taste receptor type 2 member 140011
Taste receptor type 2 member 130011
Taste receptor type 2 member 100011
Taste receptor type 2 member 90011
Taste receptor type 2 member 80011
Taste receptor type 2 member 70011
Taste receptor type 2 member 50011
Taste receptor type 2 member 40011
Taste receptor type 2 member 30011
Taste receptor type 2 member 10011
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Acetylcholinesterase0202
Cholinesterase0202
dopamine D1 receptor4004
Alkaline phosphatase, tissue-nonspecific isozyme0202
Alkaline phosphatase, placental type0101
Alkaline phosphatase, tissue-nonspecific isozyme 0202
Intestinal-type alkaline phosphatase0101
Intestinal-type alkaline phosphatase0101
5'-nucleotidase0101
Phospholipase A-2-activating protein0101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Type-1A angiotensin II receptor 0101
Type-1B angiotensin II receptor0202
Type-2 angiotensin II receptor0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0202
5-hydroxytryptamine receptor 1A0101
Type-1 angiotensin II receptor0101
Prothrombin 0101
Cationic trypsin0101
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase type 20012
Metallo-beta-lactamase VIM-11 0001
Metallo-beta-lactamase VIM-20001
Metallo-beta-lactamase VIM-19 0001
Beta-lactamase 0001
Metallo-beta-lactamase0001
streptokinase A precursor0022
Beta-lactamase0001
Beta-lactamase SHV-10001
Beta-lactamase0001
Beta-lactamase TEM0001
B2 metallo-beta-lactamase 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0012
Metallo-b-lactamase 0001
Beta-lactamase IMP-1 0001
BlaVIM-1 0001
Beta-lactamase 0001
Carbapenem-hydrolyzing beta-lactamase KPC0001
Beta-lactamase class B VIM-2 0012
Beta-lactamase 0001
Mas-related G-protein coupled receptor member X20011
Aldehyde oxidase 1 0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
ClpP1001
Thymidylate synthase 0101
Thymidylate synthase 0101
transcriptional regulator ERG isoform 33003
DNA polymerase beta3003
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
transactivating tegument protein VP16 [Human herpesvirus 1]0101
caspase-1 isoform alpha precursor2002
nuclear receptor coactivator 3 isoform a0101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30103
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Bifunctional purine biosynthesis protein ATIC0202
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-72002
Solute carrier organic anion transporter family member 1A30103
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Trifunctional purine biosynthetic protein adenosine-30101
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0204
Solute carrier organic anion transporter family member 1B30002
Broad substrate specificity ATP-binding cassette transporter ABCG20102
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
Chain E, Fibrin beta chain0101
T cell receptor, partial1001
luteinizing hormone receptor1001
integrase, partial0101
chaperonin-containing TCP-1 beta subunit homolog1001
lens epithelium-derived growth factor p750101
Caspase 6, apoptosis-related cysteine peptidase0001
TSHR protein1001
Apoptotic peptidase activating factor 10101
isocitrate dehydrogenase 1, partial1001
serine-protein kinase ATM isoform a1001
neutrophil cytosol factor 10101
caspase-9 isoform alpha precursor0101
pyruvate kinase PKM isoform a1001
caspase-3 isoform a preproprotein0101
protein AF-9 isoform a0001
replicative DNA helicase0001
recombinase A0011
POsterior Segregation0011
DNA repair protein RAD52 homolog isoform a0001
neuropeptide S receptor isoform A3003
Glutathione reductase0101
Glutathione reductase, mitochondrial0102
Glycoprotein hormones alpha chain1001
Dihydrolipoyl dehydrogenase, mitochondrial0102
Microtubule-associated protein tau0112
Cruzipain0101
Alpha-synuclein3306
Thioredoxin reductase 1, cytoplasmic0102
Dihydrolipoyl dehydrogenase 0102
Zinc finger protein mex-50011
Glucocorticoid receptor010217
Sex hormone-binding globulin0022
Glycine receptor subunit alpha-1010010
Glycine receptor subunit beta010010
Glycine receptor subunit alpha-2010010
Glycine receptor subunit alpha-3010010
Matrilysin0101
Multidrug transporter MdfA0202
Protein mono-ADP-ribosyltransferase PARP150101
Corticosteroid-binding globulin0202
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial0101
Solute carrier family 2, facilitated glucose transporter member 90112
vasopressin V1b receptor1001
relaxin receptor 1 isoform 11001
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Tumor necrosis factor0101
Cholinesterase0101
Adenosine receptor A2b0101
Chitotriosidase-10213
Endochitinase B10213
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Endolysin0011
Carbonic anhydrase 0101
Beta-carbonic anhydrase 10101
Carbonic anhydrase0101
Carbonic anhydrase 30202
Gag-Pol polyprotein0101
Gag-Pol polyprotein0101
Protease 0303
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
Chain D, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)0101
Chain A, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)0101
Chain A, Beta-arrestin 10011
luciferase0001
Estrogen receptor0517
Progesterone receptor0304
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Glutamine synthetase0011
Nociceptin receptor0011
Estrogen receptor beta0516
Voltage-dependent calcium channel subunit alpha-2/delta-10102
Voltage-dependent calcium channel subunit alpha-2/delta-20101
Chain A, dATP pyrophosphohydrolase0101
Chain A, Adenylate cyclase type 50101
Chain B, Adenylate cyclase type 20101
Prolyl 4-hydroxylase, beta polypeptide0001
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
HLA class I histocompatibility antigen, A alpha chain 0011
Estrogen receptor0113
Gastric inhibitory polypeptide receptor0101
Estrogen receptor beta0113
DNA dC->dU-editing enzyme APOBEC-3F isoform a1001
ATP-dependent translocase ABCB10101
Quinolone resistance protein NorA0102
DNA topoisomerase 10101
ATP-dependent translocase ABCB10101
Chromaffin granule amine transporter0101
Synaptic vesicular amine transporter0101
Synaptic vesicular amine transporter0213
Synaptic vesicular amine transporter0101
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
Retinol-binding protein 40011
Beta-lactoglobulin0011
Butyrophilin subfamily 3 member A10023
4-hydroxy-3-methylbut-2-enyl diphosphate reductase0101
Farnesyl diphosphate synthase0101
H0202
Phosphotransferase 0101
Farnesyl diphosphate synthase0101
Chain A, Activated Factor Xa Heavy Chain0101
Suppressor of tumorigenicity 14 protein0101
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, 146aa long hypothetical transcriptional regulator0011
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain B, Anthranilate phosphoribosyltransferase0101
Chain C, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Anthranilate phosphoribosyltransferase0101
Pyruvate kinase PKM0011
Carbonic anhydrase 0101
Chain A, CES1 protein0101
DNA polymerase III, partial1001
NPC intracellular cholesterol transporter 1 precursor1001
interferon gamma precursor0001
ubiquitin-conjugating enzyme E2 N0101
Serine/threonine-protein kinase D30101
Lysosomal acid glucosylceramidase0011
Protein kinase C gamma type0101
Protein kinase C alpha type0101
Protein kinase C beta type0101
Tyrosine-protein kinase Lck0101
Protein kinase C delta type0101
Protein kinase C epsilon type0101
Protein kinase C zeta type0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Steroid hormone receptor ERR10101
Transcriptional activator protein LuxR0101
Protein kinase C alpha type0101
Protein kinase C eta type0101
Substance-P receptor0202
B2 bradykinin receptor0202
Adenosine receptor A10202
C-8 sterol isomerase0101
Protein kinase C iota type0101
Estrogen-related receptor gamma0101
Protein kinase C gamma type0101
Protein kinase C beta type0101
Phospholipase D1 0101
Protein kinase C epsilon type0101
Protein kinase C theta type0101
Protein kinase C zeta type0101
Protein kinase C delta type0101
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Platelet-activating factor acetylhydrolase0101
Phospholipase D10101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0213
Serine/threonine-protein kinase D10101
Protein kinase C eta type0101
Emopamil-binding protein-like0101
7-dehydrocholesterol reductase0112
Protein kinase C theta type0101
Sodium/bile acid cotransporter0001
Solute carrier organic anion transporter family member 1A40203
Solute carrier organic anion transporter family member 2B1 0001
Sodium/bile acid cotransporter0102
Solute carrier organic anion transporter family member 1A10102
Solute carrier organic anion transporter family member 1A20001
Ileal sodium/bile acid cotransporter0001
Ileal sodium/bile acid cotransporter0102
Sodium/bile acid cotransporter0102
Ileal sodium/bile acid cotransporter0001
G-protein coupled bile acid receptor 10011
Solute carrier organic anion transporter family member0001
Solute carrier organic anion transporter family member 4A10001
Solute carrier organic anion transporter family member 1C10101
Solute carrier organic anion transporter family member 1A10001
Bile salt export pump0001
Solute carrier family 22 member 80101
Solute carrier organic anion transporter family member 1B10001
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
heat shock protein HSP 90-alpha isoform 20101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Dihydroxyacetone phosphate acyltransferase0001
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
Tetracycline resistance protein, class B0001
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
Neutrophil collagenase0202
Collagenase 30101
Cannabinoid receptor 10101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Integrase 0101
Cereblon isoform 40202
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
DNA-binding protein Ikaros0001
DNA damage-binding protein 10112
Protein cereblon0214
procathepsin L isoform 1 preproprotein0101
D-alanyl-D-alanine dipeptidase0101
eyes absent homolog 2 isoform a1001
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
Farnesyl diphosphate synthase0101
Matrix metalloproteinase-140101
Geranylgeranyl pyrophosphate synthase0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]