Page last updated: 2024-09-27

Zygomycosis

Infection in humans and animals caused by fungi in the class Zygomycetes. It includes MUCORMYCOSIS and entomophthoramycosis. The latter is a tropical infection of subcutaneous tissue or paranasal sinuses caused by fungi in the order Entomophthorales. Phycomycosis, closely related to zygomycosis, describes infection with members of Phycomycetes, an obsolete classification.

Synonyms(1)

Synonym
Zygomycosis

Research Excerpts

Overview

ExcerptReference
"Gastric zygomycosis is a rare but potentially lethal complication in transplant patients."( Buckels, JA; Hubscher, SG; McMaster, P; Vera, A, 2002)
"Zygomycosis is an opportunistic fungal infection that is increasingly reported in hematological patients."( Anagnostopolous, I; Gleissner, B; Schilling, A; Siehl, I; Thiel, E, 2004)
"Zygomycosis is associated with a high mortality in immunosuppressed patients."( Alexander, D; Crompton, JA; Shihab, FS; Somerville, T, 2004)
"The frequency of zygomycosis is increasing in recent years and these infections respond very poorly to currently available antifungal agents, so new approaches to develop strategies to prevent and treat zygomycosis are urgently needed."( Nagy, E; Nyilasi, I; Papp, T; Takó, M; Vágvölgyi, C, 2005)
"Zygomycosis is an emerging infection worldwide."( Chakrabarti, A; Das, A; George, VK; Mandal, J; Panda, N; Rao, P; Sakhuja, V; Shivaprakash, MR; Tarai, B; Verma, SC, 2006)
"Cutaneous zygomycosis is being increasingly recognized as a serious and life-threatening infection in debilitated and immunosuppressed patients, including transplant patients."( Dave, SP; Vernon, SE, 2006)
"Zygomycosis is increasingly reported as a cause of life-threatening fungal infections."( Bennett, CL; Blum, W; Chamilos, G; Evens, A; Kennedy, L; Kontoyiannis, DP; McKoy, JM; Mehta, J; Mullane, K; Palella, F; Parada, J; Scheetz, MH; Tallman, MS; Trifilio, SM; Yarnold, PR, 2007)
"Zygomycosis is an infrequent and difficult-to-treat fungal infection that is found in patients with underlying immunocompromised states."( Forrest, GN; Mankes, K, 2007)
"Cutaneous zygomycosis is a rare but severe fungal infection with high risk of dissemination."( Oomen, MW; Pajkrt, D; Schouten-van Meeteren, AY; van den Berg, YL; van den Bos, C; van Furth, AM; van Well, GT; Visser, DH, 2007)
"Zygomycosis is a frequently lethal invasive infection in high-risk patients such as the immunocompromised [especially haematopoietic stem cell transplant (HSCT) recipients] and patients with type 2 diabetes mellitus."( Rogers, TR, 2008)
"Zygomycosis is an emerging frequently fatal opportunistic mycosis whose immunopathogenesis is poorly understood."( Chamilos, G; Gilliet, M; Halder, G; Hu, J; Kontoyiannis, DP; Lewis, RE; Xiao, L; Zal, T, 2008)
"Zygomycosis is an emerging opportunistic mycosis among immunocompromised patients with a particularly poor prognosis."( Chamilos, G; Kontoyiannis, DP; Lewis, RE, 2008)
"Zygomycosis is a rare but very aggressive fungal infection mainly seen in immunocompromised patients."( Adler, N; Gottlieb, LJ; Seitz, IA, 2008)
"Zygomycosis is an invasive fungal infection with extremely high mortality caused by filamentous fungi which belong to Class Zygomycetes (Rhizopus spp."( Takakura, S, 2008)
"Cutaneous zygomycosis is a rare but serious infection in trauma patients."( Alkhal, A; Almaslamani, M; Alsoub, H; Dannaoui, E; Garcia-Hermoso, D; Taj-Aldeen, SJ, 2009)
"Zygomycosis is a rare, but life-threatening, deep fungal infection that appears in immunologically or metabolically compromised hosts."( Katayama, N; Nakase, K; Sekine, T; Sugawara, Y; Suzuki, K, 2009)
"Breakthrough zygomycosis is increasingly observed among patients at high risk for fungal infection who are receiving voriconazole, reflecting either selective pressure or voriconazole-associated alterations in Zygomycetes virulence."( Ben-Ami, R; Chamilos, G; Kontoyiannis, DP; Lamaris, GA; Lewis, RE; Samonis, G, 2009)
"Zygomycosis is an opportunistic fungal infection with a fulminant course."( Garg, A; Garg, J; Parija, SC; Sujatha, S, 2009)
"Zygomycosis is an invasive infection that can occur particularly in patients with haematological malignancy."( Caira, M; Fianchi, L; Pagano, L; Valentini, CG, 2009)
"Zygomycosis is usually an invasive mycotic disease caused by fungi in the class Zygomycetes."( Ito, H; Kimura, M; Makimura, K; Satoh, K; Toyazaki, N; Udagawa, S, 2009)
"Zygomycosis is a difficult to treat and frequently fatal infection affecting immunocompromised and, rarely, immunocompetent patients."( Petrikkos, GL, 2009)
"Zygomycosis is an opportunistic fungal infection mainly affecting patients with diabetes mellitus, immunodeficiency, and malignancies."( Azadi, L; Bagheri, J; Chitsaz, S; Mandegar, MH; Rayatzadeh, H; Razavi, J, 2009)
"Zygomycosis is a threat in uncontrolled diabetes."( Bhansali, A; Chakrabarti, A; Chatterjee, SS; Das, A; Kaur, A; Panda, N; Sakhuja, V; Shivaprakash, MR; Singhi, S; Varma, SC, 2009)
"Rhino-orbital zygomycosis is a life-threatening fungal infection generally occurring in patients with an underlying disorder, such as diabetes mellitus with ketoacidosis or with immunocompromising factors, although it may rarely appear in healthy individuals."( Arora, V; Chander, J; Gulati, N; Kaur, J; Mohan, H; Nagarkar, N; Sood, S, 2011)
"Subcutaneous zygomycosis is an uncommon condition observed in tropics."( Capoor, MR; Dhawan, J; Khanna, G; Ramam, M; Ramesh, V; Sugandhan, S, 2010)
"However, renal zygomycosis is an exception and the patients in both of our cases had no identifiable underlying disorder and recovered successfully without nephrectomy."( Ansari, MS; Dhole, TN; Dixit, A; Marak, RS; Misra, R; Prasad, KN, 2010)
"Subcutaneous zygomycosis is a chronic infection caused by fungus of the order Entomophthorales."( Das, S; Goyal, A; Gupta, N; Jain, S, 2010)
"Zygomycosis is highly invasive fungal infection, with high mortality rate."( Attri, A; Chander, J; Kaur, J; Mohan, H, 2010)
"Zygomycosis is an infection caused by opportunistic fungi of the Zygomycetes class, specifically those from the Mucorales and Entomophthorales orders."( Alkmim-Teixeira, GC; Auxiliadora-Martins, M; Basile-Filho, A; Bellissimo-Rodrigues, F; Carlotti, CG; Machado-Viana, J; Martins-Filho, OA; Nicolini, EA, 2010)
"Isolated renal zygomycosis is a life-threatening infection and difficult to diagnose ante mortem due to varied presentations."( Ansari, MS; Bhadoria, D; Chipde, SS; Kapoor, R; Kumar, J; Lal, H; Mandhani, A; Marak, RS; Naval, R; Pradhan, MR; Prakash, A; Ranjan, P; Sharma, RK; Singh, M; Singh, V; Srivastava, A, 2012)
"The prevalence of zygomycosis is generally very low (-5% of CNS infections) compared with that of other fungal infections."( Kimura, Y; Kuriyama, M; Naiki, H; Ookoshi, T; Ueno, A; Yoneda, M, 2012)
"Pulmonary zygomycosis is an uncommon infection that occurs mostly in immunocompromised patients."( Akuthota, P; Kelly, E; Roberts, DH; Rosenthal, ES; Theisen-Toupal, J; Zwicker, JI, 2012)
"Aspergillosis and zygomycosis are life-threatening fungal infections in immunocompromised patients."( Beltran, C; Bourge, RC; Bourke, P; Castro, P; Rabagliati, R; Verdejo, H; Winter, JL, 2012)
"Zygomycosis is a rare life-threatening fungal infection affecting mostly patients with predisposing conditions such as diabetes mellitus, immunodeficiency, haemochromatosis or major trauma."( Costantino, F; Di Biasi, C; di Coste, A; Duse, M; Ernesti, I; Melengu, T; Savastano, V; Schiavi, L; Tarani, L, 2013)
"Zygomycosis is a rare opportunistic fungal infection in immunocompetent patients."( Goel, MM; Gupta, C; Kumar, S; Singh, AK, 2014)
"Zygomycosis is an opportunistic infection generally found in immunocompromised individuals."( Blake, P; Dominguez, AR; Sirignano, S; Turrentine, JE, 2014)
"Zygomycosis is an invasive disease that affects both immunocompetent and immunocompromised, depending on the type of strain."( Felippu Neto, A; Fuks, FB; Miguita e Souza, J; Oliveira, CA; Sproesser Junior, AJ, 2014)

Context

ExcerptReference
"The frequency of zygomycosis has been increasing over the past 10 years; infections have been identified in up to 6."( Brown, J, 2005)
"However, zygomycosis has also been reported in individuals without known risk factors."( Rogers, TR, 2008)
"The treatment of zygomycosis has two cornerstones, namely, surgery and antifungal drugs."( Cornely, OA; Rüping, MJ; Vehreschild, JJ, 2009)

Treatment

ExcerptReference
"Because resection is a cornerstone of treatment for zygomycosis, the authors anticipate a growing need for plastic surgery involvement for both surgical debridement with limb and tissue-sparing procedures, and for reconstructive options that effectively treat the disease while preserving both function and esthetics."( Song, KR; Wong, MS; Yeung, C, 2008)
"We concluded that to treat zygomycosis effectively, a multidisciplinary team approach is needed, focusing on immediate diagnosis, empirical antifungal therapy, reversal of underlying predisposing factors, and early surgical debridement."( Adler, N; Gottlieb, LJ; Seitz, IA, 2008)

Research

Studies (289)

TimeframeStudies, This Condition (%)All Conditions %
pre-199017 (5.88)23.3326
1990's10 (3.46)12.5806
2000's155 (53.63)18.1394
2010's96 (33.22)28.8240
2020's11 (3.81)9.53
DrugIndicatedRelationship StrengthStudiesTrials
salicylic acid0low10
uric acid0low10
1-anilino-8-naphthalenesulfonate0low10
chlorpromazine0low10
ciprofloxacin0low10
deferoxamine0low10
fluconazole0low140
flucytosine0low10
itraconazole0low10
ketoconazole0low80
mitoxantrone0low10
potassium iodide0low170
thalidomide0low10
trifluoperazine0low10
2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5-((phenylamino)carbonyl)-2h-tetrazolium hydroxide0low10
prednisolone0low10
prednisone0low20
chloramphenicol0low10
galactose0low10
carbostyril0low10
cycloheximide0low10
chloroform0low10
cytarabine0low20
linalool0low10
methylprednisolone0low20
boric acid0low10
pyrazines0low10
limestone0low10
fusarium0low80
erythromycin0low10
vancomycin0low10
d-alpha tocopherol0low10
cladribine0low10
vidarabine0low10
iodine0low40
daunorubicin0low10
alkenes0low10
calcium oxalate0low10
idarubicin0low20
propiconazole0low30
itraconazole0low440
trazodone hydrochloride0low10
cephalosporin c0low20
triazoles0medium701
enrofloxacin0low10
voriconazole0low380
nsc-1727550low20
imatinib mesylate0low10
methotrexate0low20
deferasirox0low10
lenalidomide0low10
deoxycholic acid0low60
cortisone0low10
trimethoprim, sulfamethoxazole drug combination0low30
bortezomib0low10
epiglucan0low10
inositol 3-phosphate0low10
oleic acid0low20
posaconazole0medium401
l 743,8720low100
micafungin0low30
squalene0low10
fludarabine0low10
sesquiterpenes0low10
mercaptopurine0low10
terbinafine0low50
cancidas0low10
vicriviroc0low10
galactomannan0low10
gamma-linolenic acid0low10
phenylephrine hydrochloride0low110
muscalure0low10
cefepime0low10
rhizoxin0low10
isavuconazole0low10
fenpyroximate0low10
nystatin a10low20
dextrothyroxine0low10
hachimycin0low10
ants0low10
7-hydroxycalamenene0low10
ceftiofur0low10
phosphatidylcholines0medium81
amphotericin b, deoxycholate drug combination0low50
mannans0low10
interleukin-80low10
tetracycline0low10
calca protein, human0low10
eye0low20

Protein Targets (1,021)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain B, pheromone binding protein0011
Chain A, pheromone binding protein0011
Chain A, JmjC domain-containing histone demethylation protein 3A7007
Chain A, RNA-directed RNA polymerase NS50101
acid sphingomyelinase4004
thioredoxin reductase150015
USP1 protein, partial160016
TDP1 protein330033
vitamin D3 receptor isoform VDRA130013
importin subunit beta-1 isoform 16006
flap endonuclease 16006
serine/threonine-protein kinase PLK15005
snurportin-16006
peptidyl-prolyl cis-trans isomerase NIMA-interacting 16006
GTP-binding nuclear protein Ran isoform 13003
DNA polymerase eta isoform 15005
DNA polymerase iota isoform a (long)130013
urokinase-type plasminogen activator precursor8008
plasminogen precursor8008
urokinase plasminogen activator surface receptor precursor8008
geminin300030
DNA polymerase kappa isoform 1130013
fibroblast growth factor 22 isoform 1 precursor0001
Mitogen-activated protein kinase 130101
Beta-lactamase0505
Transthyretin0112
Fatty acid-binding protein, intestinal0112
Fatty acid-binding protein, adipocyte0314
Cyclin-A20101
Cannabinoid receptor 10011
Cyclin-dependent kinase 20123
Choline O-acetyltransferase0101
Mitogen-activated protein kinase 120101
Guanine nucleotide-binding protein G6006
Fatty acid-binding protein 50112
Fatty acid-binding protein 50011
Mitogen-activated protein kinase 110101
Mitogen-activated protein kinase 140101
Chain A, HADH2 protein100010
Chain B, HADH2 protein100010
Chain A, Cruzipain4004
interleukin 84004
phosphopantetheinyl transferase9009
GLS protein6006
glucocorticoid receptor [Homo sapiens]220022
farnesoid X nuclear receptor210021
peroxisome proliferator-activated receptor delta160016
vitamin D (1,25- dihydroxyvitamin D3) receptor170017
tumor necrosis factor1001
nuclear factor erythroid 2-related factor 2 isoform 1230023
peripheral myelin protein 22140014
lamin isoform A-delta10220022
Cytochrome P450 1A20314
Cytochrome P450 3A4016021
Cytochrome P450 2D60718
Cytochrome P450 2C9 010111
Cytochrome P450 2C190505
Nuclear receptor ROR-gamma5005
Potassium voltage-gated channel subfamily H member 2015016
Aurora kinase B0101
Broad substrate specificity ATP-binding cassette transporter ABCG208011
Chain A, TYROSYL-DNA PHOSPHODIESTERASE8008
thyroid stimulating hormone receptor3003
retinoic acid nuclear receptor alpha variant 1250025
retinoid X nuclear receptor alpha250025
estrogen nuclear receptor alpha350035
thyroid hormone receptor beta isoform 2220022
Beta-lactamase0102
Chain H, Proteasome component PUP10101
Chain I, Proteasome component PUP30101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Proteasome subunit beta type-110102
RAR-related orphan receptor gamma210021
Fumarate hydratase120012
PPM1D protein8008
AR protein270027
caspase 7, apoptosis-related cysteine protease4004
estrogen receptor 2 (ER beta)150015
nuclear receptor subfamily 1, group I, member 3190019
progesterone receptor210021
cytochrome P450 family 3 subfamily A polypeptide 4180018
EWS/FLI fusion protein220022
estrogen-related nuclear receptor alpha280028
pregnane X nuclear receptor220022
polyprotein120012
peroxisome proliferator activated receptor gamma160016
caspase-34004
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a150015
nuclear receptor subfamily 1, group I, member 24004
Histone H2A.x140014
Caspase-74004
caspase-34004
heat shock protein beta-18008
26S proteasome non-ATPase regulatory subunit 110101
26S proteasome non-ATPase regulatory subunit 120101
26S proteasome non-ATPase regulatory subunit 140101
Proteasome subunit alpha type-70102
Histone deacetylase 30202
ATP-binding cassette sub-family C member 3022022
Multidrug resistance-associated protein 4022023
26S proteasome non-ATPase regulatory subunit 30101
Carbonic anhydrase 120303
Voltage-dependent calcium channel gamma-2 subunit160016
Bile salt export pump029029
Prothrombin0101
Chymotrypsinogen A0404
Carbonic anhydrase 10707
Carbonic anhydrase 20819
Interferon beta220022
Cellular tumor antigen p53280028
Carbonic anhydrase 30303
Cathepsin B0101
Neutrophil elastase0101
Cathepsin G0202
Lysosomal protective protein0101
Chymotrypsinogen B0101
26S proteasome regulatory subunit 6A0101
Glutamate receptor 2170017
Nuclear factor NF-kappa-B p105 subunit0101
Proteasome subunit beta type-10103
Carbonic anhydrase 40606
Carbonic anhydrase 60303
Chymase0101
Proteasome subunit alpha type-10102
Proteasome subunit alpha type-20102
Proteasome subunit alpha type-30102
Proteasome subunit alpha type-40102
Proteasome subunit beta type-80102
Proteasome subunit beta type-80101
Proteasome subunit beta type-90102
Proteasome subunit alpha type-50102
Proteasome subunit beta type-40102
Proteasome subunit beta type-60102
Proteasome subunit beta type-50204
Carbonic anhydrase 5A, mitochondrial0505
26S proteasome regulatory subunit 70101
Lon protease homolog, mitochondrial0101
Proteasome subunit beta type-100102
Carbonic anhydrase 70303
26S proteasome regulatory subunit 6B0101
26S proteasome non-ATPase regulatory subunit 80101
Proteasome subunit beta type-30102
Proteasome subunit beta type-20103
26S proteasome non-ATPase regulatory subunit 70101
26S proteasome non-ATPase regulatory subunit 40101
26S proteasome complex subunit SEM10101
Proteasome subunit alpha type-60113
26S proteasome regulatory subunit 40101
26S proteasome regulatory subunit 80101
26S proteasome regulatory subunit 10B0101
Beta-carbonic anhydrase 10101
Nuclear factor NF-kappa-B p100 subunit 0101
Transcription factor p650101
26S proteasome non-ATPase regulatory subunit 20101
Histone deacetylase 10303
26S proteasome non-ATPase regulatory subunit 60101
Proteasomal ubiquitin receptor ADRM10101
Carbonic anhydrase 90505
ATP-dependent Clp protease proteolytic subunit0112
Carbonic anhydrase 130202
NACHT, LRR and PYD domains-containing protein 3 0101
Proteasome subunit alpha-type 80102
Histone deacetylase 20202
Canalicular multispecific organic anion transporter 1021021
ATPase family AAA domain-containing protein 5130013
Proteasome subunit beta type-70102
26S proteasome non-ATPase regulatory subunit 10101
Ataxin-2180018
Carbonic anhydrase 150303
Histone deacetylase 80303
Histone deacetylase 60303
Carbonic anhydrase 140303
26S proteasome non-ATPase regulatory subunit 130101
Carbonic anhydrase 5B, mitochondrial0303
GLI family zinc finger 3250025
1,3-beta-D-glucan synthase catalytic subunit 0101
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
Chain A, serum paraoxonase0101
nuclear receptor ROR-gamma isoform 1100010
Neutrophil cytosol factor 10101
Poly [ADP-ribose] polymerase tankyrase-20101
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase type 20001
Metallo-beta-lactamase VIM-11 0001
Metallo-beta-lactamase VIM-20001
Metallo-beta-lactamase VIM-19 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase0001
Beta-lactamase 0001
Beta-lactamase0001
Solute carrier family 22 member 50101
Beta-lactamase0001
Beta-lactamase SHV-10001
Beta-lactamase0001
Beta-lactamase0001
Kappa-type opioid receptor0001
Solute carrier family 15 member 10101
Beta-lactamase TEM0001
Beta-lactamase0001
B2 metallo-beta-lactamase 0001
Solute carrier family 15 member 20101
Metallo-beta-lactamase VIM-130001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0001
Metallo-beta-lactamase0001
Solute carrier family 15 member 20101
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-b-lactamase 0001
BlaVIM-1 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase class B VIM-2 0001
Beta-lactamase VIM-1 0001
aldehyde dehydrogenase 1 family, member A1150015
G150015
cytochrome P450 2D6110011
aryl hydrocarbon receptor100010
activating transcription factor 69009
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a8008
streptokinase A precursor0044
lethal factor (plasmid)5005
Dihydroxyacetone phosphate acyltransferase0002
HLA class I histocompatibility antigen, B alpha chain 150015
30S ribosomal protein S60314
30S ribosomal protein S70314
50S ribosomal protein L150314
50S ribosomal protein L100314
50S ribosomal protein L110314
50S ribosomal protein L7/L120314
50S ribosomal protein L190314
50S ribosomal protein L10314
50S ribosomal protein L200314
50S ribosomal protein L270314
50S ribosomal protein L280314
50S ribosomal protein L290314
50S ribosomal protein L310314
50S ribosomal protein L31 type B0314
50S ribosomal protein L320314
50S ribosomal protein L330314
50S ribosomal protein L340314
50S ribosomal protein L350314
50S ribosomal protein L360314
30S ribosomal protein S100314
30S ribosomal protein S110314
30S ribosomal protein S120314
30S ribosomal protein S130314
30S ribosomal protein S160314
30S ribosomal protein S180314
30S ribosomal protein S190314
30S ribosomal protein S200314
30S ribosomal protein S20314
30S ribosomal protein S30314
30S ribosomal protein S40314
30S ribosomal protein S50314
30S ribosomal protein S80314
30S ribosomal protein S90314
50S ribosomal protein L130314
50S ribosomal protein L140314
50S ribosomal protein L160314
50S ribosomal protein L230314
30S ribosomal protein S150314
50S ribosomal protein L170314
50S ribosomal protein L210314
50S ribosomal protein L300314
50S ribosomal protein L60314
30S ribosomal protein S140314
30S ribosomal protein S170314
30S ribosomal protein S10314
50S ribosomal protein L180314
50S ribosomal protein L20314
50S ribosomal protein L30314
50S ribosomal protein L240314
50S ribosomal protein L40314
50S ribosomal protein L220314
50S ribosomal protein L50314
30S ribosomal protein S210314
50S ribosomal protein L250314
50S ribosomal protein L36 20314
Inositol hexakisphosphate kinase 1150015
Methionine--tRNA ligase, mitochondrial0011
cytochrome P450 2C9, partial150015
Luciferase7007
hypoxia-inducible factor 1 alpha subunit8008
v-jun sarcoma virus 17 oncogene homolog (avian)9009
acetylcholinesterase5005
ATAD5 protein, partial8008
NFKB1 protein, partial4004
Microtubule-associated protein tau130013
Thrombopoietin4004
Smad37007
NADPH oxidase 10202
67.9K protein120012
Snq2p0002
IDH1150015
euchromatic histone-lysine N-methyltransferase 2160016
Adenylate cyclase type 1 0202
thyroid stimulating hormone receptor9009
Spike glycoprotein0123
Replicase polyprotein 1ab0123
cytochrome P450 2D6 isoform 14004
cellular tumor antigen p53 isoform a9009
D(1A) dopamine receptor3003
chromobox protein homolog 1180018
potassium voltage-gated channel subfamily H member 2 isoform d6006
histone deacetylase 9 isoform 31001
mitogen-activated protein kinase 1100010
atrial natriuretic peptide receptor 2 precursor3003
ras-related protein Rab-9A6006
serine/threonine-protein kinase mTOR isoform 16006
survival motor neuron protein isoform d110011
cytochrome P450 3A4 isoform 18008
M-phase phosphoprotein 88008
histone acetyltransferase KAT2A isoform 1120012
muscarinic acetylcholine receptor M15005
Gamma-aminobutyric acid receptor subunit pi8109
Solute carrier family 22 member 1 0505
Polyunsaturated fatty acid lipoxygenase ALOX15B8008
Transmembrane protease serine 20123
Glutamate receptor ionotropic, NMDA 2D0101
Transient receptor potential cation channel subfamily V member 10101
Glutamate receptor ionotropic, NMDA 3B0101
Voltage-dependent L-type calcium channel subunit alpha-1F0404
Bile salt export pump0404
5-hydroxytryptamine receptor 40606
Potassium channel subfamily K member 20101
Epidermal growth factor receptor0303
Albumin0147
Albumin0022
Major prion protein0011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10303
Receptor tyrosine-protein kinase erbB-20303
Major prion protein0011
Integrin beta-38008
Tyrosine-protein kinase Fyn0404
Procathepsin L0123
Aldo-keto reductase family 1 member B1010010
Muscarinic acetylcholine receptor M2010010
Muscarinic acetylcholine receptor M40606
ATP-dependent translocase ABCB1014016
Muscarinic acetylcholine receptor M10101
Muscarinic acetylcholine receptor M30101
Muscarinic acetylcholine receptor M40101
Integrin alpha-IIb8008
5-hydroxytryptamine receptor 1A0101
5-hydroxytryptamine receptor 2C0214
Muscarinic acetylcholine receptor M50101
Muscarinic acetylcholine receptor M50202
Alpha-2A adrenergic receptor0909
Replicase polyprotein 1a0123
Replicase polyprotein 1ab0123
Replicase polyprotein 1ab0224
Cys-loop ligand-gated ion channel0101
Calmodulin-10224
Replicase polyprotein 1ab0325
Muscarinic acetylcholine receptor M20101
Muscarinic acetylcholine receptor M10707
Polyunsaturated fatty acid lipoxygenase ALOX150303
Angiotensin-converting enzyme0606
D(2) dopamine receptor0405
5-hydroxytryptamine receptor 2A0314
Gamma-aminobutyric acid receptor subunit beta-18109
Alpha-1B adrenergic receptor0808
Sphingomyelin phosphodiesterase0101
Alpha-2B adrenergic receptor0606
Gamma-aminobutyric acid receptor subunit delta8109
Gamma-aminobutyric acid receptor subunit gamma-28109
Alpha-2C adrenergic receptor0202
D0202
D(3) dopamine receptor0202
5-hydroxytryptamine receptor 1A0404
Alpha-2B adrenergic receptor0303
Gamma-aminobutyric acid receptor subunit alpha-58109
Gamma-aminobutyric acid receptor subunit alpha-38109
D(2) dopamine receptor0101
Muscarinic acetylcholine receptor M30404
Substance-K receptor0808
D(1A) dopamine receptor0405
D(4) dopamine receptor0405
D(1B) dopamine receptor0102
Adenylate cyclase type 30202
Alpha-2C adrenergic receptor0303
UDP-glucuronosyltransferase 1A40001
Alpha-2A adrenergic receptor0303
Gamma-aminobutyric acid receptor subunit gamma-18109
Gamma-aminobutyric acid receptor subunit alpha-28109
Alpha-1D adrenergic receptor0606
Sodium-dependent noradrenaline transporter 010010
Sodium-dependent dopamine transporter0202
Histamine H2 receptor0606
Alpha-1D adrenergic receptor0404
D(1B) dopamine receptor0202
Adenylate cyclase type 20202
Adenylate cyclase type 40202
5-hydroxytryptamine receptor 2A0404
5-hydroxytryptamine receptor 2C0606
Gamma-aminobutyric acid receptor subunit alpha-48109
Gamma-aminobutyric acid receptor subunit gamma-38109
5-hydroxytryptamine receptor 1B0404
Trypanothione reductase0404
Gamma-aminobutyric acid receptor subunit alpha-68109
D(4) dopamine receptor0202
5-hydroxytryptamine receptor 2B0112
Histamine H1 receptor0123
Sodium-dependent serotonin transporter0606
Melanocortin receptor 40202
5-hydroxytryptamine receptor 7 0101
Melanocortin receptor 50202
Pleiotropic ABC efflux transporter of multiple drugs0204
5-hydroxytryptamine receptor 70101
Histamine H1 receptor0404
Mu-type opioid receptor0606
Glutamate receptor ionotropic, NMDA 1 0101
D(3) dopamine receptor0405
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0101
Adenylate cyclase type 80202
Delta-type opioid receptor0606
Kappa-type opioid receptor0606
5-hydroxytryptamine receptor 2B0404
Melanocortin receptor 30202
Alpha-1A adrenergic receptor0808
Histamine H2 receptor9009
D(1A) dopamine receptor3003
5-hydroxytryptamine receptor 60404
5-hydroxytryptamine receptor 70101
Cytochrome P450 2J20303
Gastrin/cholecystokinin type B receptor0101
Spike glycoprotein111214
D(2) dopamine receptor0315
Calmodulin 0123
Gamma-aminobutyric acid receptor subunit alpha-18109
Gamma-aminobutyric acid receptor subunit beta-38109
Gamma-aminobutyric acid receptor subunit beta-28109
Aldehyde oxidase 10101
Glutamate receptor ionotropic, NMDA 2A 0101
Glutamate receptor ionotropic, NMDA 2B0101
Glutamate receptor ionotropic, NMDA 2C0101
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0404
Sodium-dependent dopamine transporter 0606
Adenylate cyclase type 60202
Adenylate cyclase type 50202
Glutamate receptor ionotropic, NMDA 10101
Aldehyde oxidase0202
Glutamate receptor ionotropic, NMDA 2A0101
Glutamate receptor ionotropic, NMDA 2B0101
Voltage-dependent L-type calcium channel subunit alpha-1S0404
Voltage-dependent L-type calcium channel subunit alpha-1C0606
Sodium channel protein type 5 subunit alpha0202
Glutamate receptor ionotropic, NMDA 2C0101
Sodium channel protein type 9 subunit alpha0101
Glutamate receptor ionotropic, NMDA 2D0101
Nuclear receptor subfamily 3 group C member 3 0606
Adenylyl cyclase 7 0202
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0101
GABA theta subunit8109
D0101
Sodium channel protein type 2 subunit alpha0101
Sigma non-opioid intracellular receptor 10505
Angiotensin-converting enzyme 2 0123
Gamma-aminobutyric acid receptor subunit epsilon8109
Sodium channel protein type 3 subunit alpha0101
Glutamate receptor ionotropic, NMDA 3A0101
Sodium channel protein type 11 subunit alpha0101
Sodium channel protein type 8 subunit alpha0101
Histamine H3 receptor0101
Sodium channel protein type 10 subunit alpha0101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE120012
Chain A, 2-oxoglutarate Oxygenase9009
cytochrome P450 2C9 precursor2002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 16006
DNA gyrase subunit B0101
DNA gyrase subunit A0101
DNA gyrase subunit B0102
DNA gyrase subunit A0103
DNA gyrase subunit B0103
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0102
DNA topoisomerase 4 subunit A0102
DNA topoisomerase 2-alpha0207
DNA gyrase subunit A0102
Multidrug resistance protein MdtK0011
DNA gyrase subunit B0101
DNA gyrase subunit A0101
Enoyl-[acyl-carrier-protein] reductase [NADH]0001
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0101
Integrase 0303
Chain A, BCL-2-RELATED PROTEIN A10033
glp-1 receptor, partial100010
nuclear factor erythroid 2-related factor 2 isoform 2130013
huntingtin isoform 25005
tyrosine-protein kinase Yes2002
muscleblind-like protein 1 isoform 15005
relaxin receptor 1 isoform 11001
bcl-2-like protein 11 isoform 10033
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
Deoxycytidine kinase0002
Adenosine receptor A30202
Rap guanine nucleotide exchange factor 43003
Chain A, Ferritin light chain9009
endonuclease IV5005
15-lipoxygenase, partial4004
SMAD family member 28008
SMAD family member 38008
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)7007
regulator of G-protein signaling 46006
isocitrate dehydrogenase 1, partial2002
nonstructural protein 17007
bromodomain adjacent to zinc finger domain 2B5005
arylsulfatase A4004
alpha-galactosidase3003
pyruvate kinase2002
heat shock protein 900022
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)4004
calcineurin A1, putative0022
thyrotropin-releasing hormone receptor1001
beta-2 adrenergic receptor2013
Bloom syndrome protein isoform 19009
peripheral myelin protein 22 isoform 14004
cytochrome P450 2C19 precursor2002
ubiquitin carboxyl-terminal hydrolase 2 isoform a3003
heat shock protein HSP 90-alpha isoform 20106
lethal(3)malignant brain tumor-like protein 1 isoform I2002
neuropeptide S receptor isoform A3003
Intermediate conductance calcium-activated potassium channel protein 40101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Transient receptor potential cation channel subfamily M member 20101
Glucocorticoid receptor010217
Steroid 17-alpha-hydroxylase/17,20 lyase0505
Histidine-rich protein PFHRP-II0101
Estrogen receptor0011
Heme oxygenase 1 0202
ATP-dependent translocase ABCB10909
Epoxide hydrolase 10002
Glycine receptor subunit alpha-1010010
Beta-1 adrenergic receptor0202
Adenosine receptor A30202
Aromatase0606
Beta-3 adrenergic receptor0202
Androgen receptor0505
Potassium-transporting ATPase subunit beta0101
Potassium-transporting ATPase alpha chain 10101
Glycine receptor subunit beta010010
ATP-dependent translocase ABCB10909
Potassium voltage-gated channel subfamily A member 30101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Acetylcholinesterase0202
Glycine receptor subunit alpha-2010010
Heme oxygenase 20202
Glycine receptor subunit alpha-3010010
Thromboxane-A synthase 0303
C-X-C chemokine receptor type 10202
Substance-P receptor0202
Platelet-activating factor receptor1203
Indoleamine 2,3-dioxygenase 10101
Adenosine receptor A2a0202
Vasopressin V2 receptor0202
Adenosine receptor A10202
Prostaglandin G/H synthase 20303
Alpha-synuclein3104
Malate dehydrogenase, cytoplasmic0303
C-C chemokine receptor type 40202
Transitional endoplasmic reticulum ATPase0101
Disintegrin and metalloproteinase domain-containing protein 171001
Cytochrome P450 1440044
Steroid C26-monooxygenase0044
Cytochrome P450 1300011
Cytochrome P450 1300011
Steroid C26-monooxygenase0044
Mycocyclosin synthase0022
Lanosterol 14-alpha demethylase0022
TAR DNA-binding protein 4391010
Nuclear receptor subfamily 1 group I member 3 0202
Lanosterol 14-alpha demethylase0628
Sterol 14-alpha demethylase0055
Estrogen receptor beta0011
Indoleamine 2,3-dioxygenase 20101
Bile acid receptor0112
14-alpha sterol demethylase 0055
Cysteinyl leukotriene receptor 10202
HSP40, subfamily A [Plasmodium falciparum 3D7]0003
heat shock protein 90, putative0005
ATP-dependent phosphofructokinase7007
dopamine D1 receptor3003
pregnane X receptor5005
atrial natriuretic peptide receptor 1 precursor2002
Sex hormone-binding globulin0011
Corticosteroid-binding globulin0202
Potassium voltage-gated channel subfamily A member 10011
Multidrug and toxin extrusion protein 10404
P531001
RPL19A0011
NPC intracellular cholesterol transporter 1 precursor4004
thyroid hormone receptor beta isoform a8008
nuclear factor NF-kappa-B p105 subunit isoform 11001
transactivating tegument protein VP16 [Human herpesvirus 1]0303
COUP transcription factor 2 isoform a0101
Glucose transporter0101
Hexose transporter 1 0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Solute carrier family 2, facilitated glucose transporter member 10101
Eukaryotic initiation factor 4A-I0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0202
Peptidyl-prolyl cis-trans isomerase FKBP30101
Peptidyl-prolyl cis-trans isomerase FKBP40101
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10101
Hypoxia-inducible factor 1-alpha0112
Endothelial PAS domain-containing protein 10101
Peptidyl-prolyl cis-trans isomerase FKBP140101
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 40101
LMP1 [Human herpesvirus 4]0002
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0202
nuclear receptor coactivator 3 isoform a0202
Thymidine kinase 2, mitochondrial0101
Thymidine kinase, cytosolic0102
Thymidine kinase0101
Thymidylate synthase0203
Thymidine kinase0101
Probable deoxycytidylate deaminase0001
Cytidine deaminase0102
E3 ubiquitin-protein ligase Mdm20101
Enoyl-[acyl-carrier-protein] reductase [NADH] 0101
Thymidine kinase0101
Deoxynucleoside kinase0101
Rap guanine nucleotide exchange factor 35005
Glutathione S-transferase P0101
Alpha-tocopherol transfer protein0011
Chain A, Breast cancer type 1 susceptibility protein1001
Chain A, ATP-DEPENDENT DNA HELICASE Q13003
runt-related transcription factor 1 isoform AML1b1001
core-binding factor subunit beta isoform 21001
histone-lysine N-methyltransferase 2A isoform 2 precursor5005
NADH-ubiquinone oxidoreductase chain 40001
72 kDa type IV collagenase0202
Carbonyl reductase [NADPH] 10001
Glutamate receptor 12002
Glutamate receptor 32002
Glutamate receptor 42002
Multidrug resistance-associated protein 1 0305
Inositol monophosphatase 14004
Reverse transcriptase/RNaseH 0226
Lysine-specific demethylase 6B0101
Lysine-specific demethylase 4A0213
Lysine-specific demethylase 5A0101
Flavin reductase (NADPH)0011
Potassium voltage-gated channel subfamily D member 30101
apical membrane antigen 1, AMA15005
Methylcytosine dioxygenase TET20101
Deoxyhypusine hydroxylase0101
Chain A, STEROID DELTA-ISOMERASE0011
Steroid Delta-isomerase0011
Vitamin D3 receptor0112
Ileal sodium/bile acid cotransporter0101
G-protein coupled bile acid receptor 10011
glucocerebrosidase2002
DNA polymerase beta3003
Chain A, Beta-lactamase8008
Motilin receptor0011
low molecular weight phosphotyrosine protein phosphatase isoform c0101
Motilin receptor0112
60 kDa chaperonin0101
60 kDa heat shock protein, mitochondrial0202
Chitinase B0101
Low molecular weight phosphotyrosine protein phosphatase0101
10 kDa heat shock protein, mitochondrial0202
Cytochrome P450 1B10101
Thiosulfate sulfurtransferase0202
60 kDa chaperonin 0202
10 kDa chaperonin 0202
NADH-ubiquinone oxidoreductase chain 10101
unnamed protein product0101
transcriptional regulator ERG isoform 33003
Lanosterol 14-alpha demethylase0134
Cytochrome P450 11B1, mitochondrial0303
Cytochrome P450 11B2, mitochondrial0303
Histone deacetylase 40101
Lanosterol 14-alpha demethylase0011
Sterol 14-alpha demethylase0224
Histone deacetylase 70101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Histone deacetylase 90101
Histone deacetylase 50101
likely tRNA 2'-phosphotransferase0101
Skn7p0001
corticotropin-releasing hormone receptor 20112
corticotropin releasing factor-binding protein0112
glycogen synthase kinase-3 beta isoform 10022
5'-nucleotidase0101
Adenosine deaminase 0002
Beta-galactosidase0101
Lipopolysaccharide heptosyltransferase 10101
PA-I galactophilic lectin0011
Jacalin0011
WRN2002
Caspase 6, apoptosis-related cysteine peptidase0001
thioredoxin glutathione reductase3003
Free fatty acid receptor 10011
Trypsin0202
Coagulation factor VII0202
Tissue factor0202
DNA polymerase III, partial2002
NPYLR7B0011
Parkin2002
hexokinase-4 isoform 11001
glucokinase regulatory protein1001
eyes absent homolog 2 isoform a1001
tumor susceptibility gene 101 protein1001
Amyloid-beta precursor protein2002
Single-stranded DNA cytosine deaminase2002
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
DNA repair protein RAD52 homolog isoform a0003
Tyrosine-protein kinase ABL10124
Cytochrome P450 2C80102
Mast/stem cell growth factor receptor Kit0112
Breakpoint cluster region protein0012
Platelet-derived growth factor receptor alpha0112
Cytochrome P450 3A50102
Carbonic anhydrase0101
GALC protein2002
Cruzipain0101
Estrogen receptor beta0102
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0101
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0202
Cytochrome P450 26A10101
Prostaglandin G/H synthase 1 0202
Prostaglandin G/H synthase 2 0101
3',5'-cyclic-AMP phosphodiesterase 0101
Camphor 5-monooxygenase0001
Phospholipase A2, major isoenzyme0101
Cytochrome P450 2C11 0101
Steroid 21-hydroxylase0101
Steroid 17-alpha-hydroxylase/17,20 lyase 0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Cholesterol side-chain cleavage enzyme, mitochondrial 0101
Indoleamine 2,3-dioxygenase 10101
Cytochrome P450 2A20101
Cytochrome P450 11B1, mitochondrial 0202
Translocator protein0101
Cytochrome P450 7A1 0101
Estrogen receptor0102
UDP-glucuronosyltransferase 1A1 0202
Gonadotropin-releasing hormone receptor0112
Type-1 angiotensin II receptor0101
Cytochrome P450 4F20101
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0202
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0101
Sodium/bile acid cotransporter0202
Cytochrome P450 7A10101
Lanosterol 14-alpha demethylase 0202
Hsf1 protein0011
Capsid protein 0123
Cereblon isoform 40303
Bromodomain-containing protein 40101
DNA-binding protein Ikaros0014
DNA damage-binding protein 10213
Protein cereblon0429
Zinc finger protein Aiolos0011
5-hydroxytryptamine receptor 3A0101
hemoglobin subunit beta1001
UDP-glucose 6-dehydrogenase0101
Solute carrier family 22 member 80001
Hypoxanthine-guanine phosphoribosyltransferase0001
UDP-glucose 6-dehydrogenase0101
Prostaglandin G/H synthase 10202
Purine nucleoside phosphorylase0011
UDP-glucuronosyltransferase 1A1 0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
ClpP1001
Thymidylate synthase 0101
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
caspase-1 isoform alpha precursor1001
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
High mobility group protein B10022
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Bifunctional purine biosynthesis protein ATIC0202
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60104
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200202
Dihydrofolate reductase 0101
Solute carrier family 22 member 80205
Solute carrier family 22 member 60202
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier organic anion transporter family member 1B30405
Solute carrier family 22 member 110002
Protein-arginine deiminase type-40202
Nuclear receptor subfamily 1 group I member 20022
Nuclear receptor subfamily 1 group I member 20011
Chain A, Probable serine/threonine-protein kinase pknB0101
hypothetical protein, conserved1001
nonstructural protein 10101
LANA0001
phospholipase A2, group III0101
interferon gamma precursor0001
histone-lysine N-methyltransferase NSD2 isoform 10001
protein AF-9 isoform a0001
dual specificity tyrosine-phosphorylation-regulated kinase 1A0001
rac GTPase-activating protein 1 isoform a0101
Vpr2002
pyruvate kinase PKM isoform b1001
Solute carrier family 22 member 20202
Solute carrier family 22 member 30202
Glycoprotein hormones alpha chain2002
Proto-oncogene tyrosine-protein kinase ROS0101
Ornithine decarboxylase1001
DNA topoisomerase 20001
Casein kinase II subunit alpha'0101
Casein kinase II subunit beta0101
Casein kinase II subunit alpha0101
DNA topoisomerase 2-beta0001
Tyrosine-protein kinase BTK0101
NEDD8-activating enzyme E1 regulatory subunit0011
Multidrug and toxin extrusion protein 20202
Casein kinase II subunit alpha 30101
NEDD8-activating enzyme E1 catalytic subunit0011
P2Y purinoceptor 120202
phosphoglycerate kinase1001
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Chain A, Adipocyte Lipid-binding Protein0011
Chain A, SERUM ALBUMIN0011
Chain A, SERUM ALBUMIN0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
putative potassium channel subunit0011
serine-protein kinase ATM isoform a1001
Fatty-acid amide hydrolase 10101
Sterol O-acyltransferase 10101
Fatty acid-binding protein, liver0202
Fatty acid-binding protein, liver0011
Seed linoleate 13S-lipoxygenase-10101
DNA topoisomerase 10101
Protein kinase C alpha type0001
Tyrosine-protein phosphatase non-receptor type 10204
Sterol O-acyltransferase 10101
Nuclear receptor subfamily 4 group A member 20011
Prostaglandin G/H synthase 20202
Peroxisome proliferator-activated receptor delta0001
Peroxisome proliferator-activated receptor alpha1012
Transient receptor potential cation channel subfamily V member 20101
lysosomal alpha-glucosidase preproprotein1001
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
Sterol 14-alpha-demethylase0022
14-alpha sterol demethylase 0022
14-alpha sterol demethylase 0022
Taste receptor type 2 member 310011
Taste receptor type 2 member 600011
Sodium/potassium/calcium exchanger 40112
Taste receptor type 2 member 140011
Taste receptor type 2 member 130011
Taste receptor type 2 member 90011
Taste receptor type 2 member 40011
Sodium/potassium/calcium exchanger 20112
luciferase0001
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Nociceptin receptor0011
Estrogen receptor beta0202
Chain A, HIV-1 PROTEASE0101
Chain B, HIV-1 PROTEASE0101
Chain A, POL polyprotein0101
Chain B, POL polyprotein0101
Chain A, POL polyprotein0101
Chain B, POL polyprotein0101
Chain A, Endothiapepsin0101
Chain A, Endothiapepsin0101
Solute carrier organic anion transporter family member 2B1 0202
Gag-Pol polyprotein0101
Gag-Pol polyprotein0101
Gag-Pol polyprotein0101
Gag-Pol polyprotein0101
Gag-Pol polyprotein0101
Gag-Pol polyprotein0101
Vasopressin V1a receptor0202
Thromboxane-A synthase0001
Protease 0114
Plasmepsin V 0101
Solute carrier organic anion transporter family member 1B10202
Protease 0213
chaperonin-containing TCP-1 beta subunit homolog1001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Solute carrier family 22 member 60101
Polyphenol oxidase 20102
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Stromelysin-10112
Tyrosine-protein phosphatase YopH0101
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Cystathionine gamma-lyase0101
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Carbonic anhydrase0101
Solute carrier family 22 member 70001
Nicotinate phosphoribosyltransferase0101
Ubiquitin-like domain-containing CTD phosphatase 10101
Carbonic anhydrase 130101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
5'-AMP-activated protein kinase subunit beta-10001
Squalene monooxygenase 0102
Adenylate kinase isoenzyme 10001
Adenylate kinase 2, mitochondrial0001
cystic fibrosis transmembrane conductance regulator0101
C-8 sterol isomerase0202
Squalene monooxygenase0202
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0202
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Tetracycline resistance protein, class B0001
Multidrug transporter MdfA0101
Neutrophil collagenase0101
Collagenase 30101
Cannabinoid receptor 10101
Solute carrier family 22 member 70001
Prostaglandin G/H synthase 10101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
HLA class I histocompatibility antigen, A alpha chain 0011
Genome polyprotein 0101
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
Ubiquitin carboxyl-terminal hydrolase 10101
Lysozyme C-10101
Protein kinase C alpha type0101
Beta-glucuronidase0101
Protein kinase C delta type0101
Protein kinase C epsilon type0101
Protein kinase C zeta type0101
Protein kinase C gamma type0101
Protein kinase C beta type0101
DNA-dependent protein kinase catalytic subunit0101
Protein kinase C eta type0101
Calcium-dependent protein kinase 40101
WD repeat-containing protein 480101
Emopamil-binding protein-like0101
Protein kinase C theta type0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Solute carrier family 2, facilitated glucose transporter member 90112
Guanine deaminase0101
Sodium-dependent serotonin transporter0101
D-alanyl-D-alanine dipeptidase0101
Transporter0101
C-C chemokine receptor type 50202
C-C chemokine receptor type 50101
Dipeptidyl peptidase 40101
Adenosylhomocysteinase0101
RNA-directed RNA polymerase 0112
Cholesterol side-chain cleavage enzyme, mitochondrial 0011
Cytochrome P450 2B60101
Cholesterol 24-hydroxylase0213
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]