Page last updated: 2024-08-05 15:17:17

pyrethroid ester insecticide

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ChEBI ID: 39116

Members (19)

MemberDefinitionClass
acrinathrinacrinathrin
allethrinsallethrin
bifenthrinA carboxylic ester obtained by formal condensation of cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylic acid and [(2-methyl-1,1'-biphenyl)-3-yl]methanol.bifenthrin; kappa-bifenthrin
bifenthrinA carboxylic ester obtained by formal condensation of the carboxy group of (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-enyl]-2,2-dimethylcyclopropanecarboxylic acid with the hydroxy group of [(2-methyl-1,1'-biphenyl)-3-yl]methanol.bifenthrin; kappa-bifenthrin
bioresmethrinbioresmethrin
cyfluthrinA carboxylic ester obtained by formal condensation between 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid and (4-fluoro-3-phenoxyphenyl)(hydroxy)acetonitrile.cyfluthrin
cyhalothrinA carboxylic ester obtained by formal condensation between 3-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropanecarboxylic acid and cyano(3-phenoxyphenyl)methanol.cyhalothrin
cypermethrinA carboxylic ester resulting from the formal condensation between 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid and the alcoholic hydroxy group of hydroxy(3-phenoxyphenyl)acetonitrile.cypermethrin
cyphenothrincyphenothrin
decamethrinA cyclopropanecarboxylate ester obtained by formal condensation between 3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylic acid and cyano(3-phenoxyphenyl)methanol. It is the active insecticide of the proinsecticide tralomethrin.deltamethrin
fenpropathrin, (+-)-isomerA cyclopropanecarboxylate ester obtained by formal condensation between 2,2,3,3-tetramethylcyclopropanecarboxylic acid and cyano(3-phenoxyphenyl)methanol.fenpropathrin
fenvalerateA carboxylic ester obtained by formal condensation between 2-(4-chlorophenyl)-3-methylbutyric acid and cyano(3-phenoxyphenyl)methanol.fenvalerate
fluvalinatefluvalinate
permethrinA cyclopropanecarboxylate ester in which the esterifying alcohol is 3-phenoxybenzyl alcohol and the cyclopropane ring is substituted with a 2,2-dichlorovinyl group and with gem-dimethyl groups.permethrin
phenothrinphenothrin
pydrin, (s-(r*,r*))-isomeresfenvalerate
resmethrinresmethrin
tetramethrintetramethrin
transfluthrinA carboxylic ester obtained by formal condensation of 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid and 2,3,5,6-tetrafluorobenzyl alcohol.transfluthrin

Research

Studies (7,526)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-1990559 (7.43)18.7374
1990's954 (12.68)18.2507
2000's1,830 (24.32)29.6817
2010's3,016 (40.07)24.3611
2020's1,167 (15.51)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials354 (3.83%)5.53%
Reviews214 (2.31%)6.00%
Case Studies200 (2.16%)4.05%
Observational12 (0.13%)0.25%
Other8,474 (91.57%)84.16%

Protein Targets (64)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
acetylcholinesteraseHomo sapiens (human)Potency31.705511
activating transcription factor 6Homo sapiens (human)Potency44.6781210
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency25.118911
apical membrane antigen 1, AMA1Plasmodium falciparum 3D7Potency28.183811
AR proteinHomo sapiens (human)Potency33.9243952
aryl hydrocarbon receptorHomo sapiens (human)Potency34.233337
bromodomain adjacent to zinc finger domain 2BHomo sapiens (human)Potency11.220211
Cellular tumor antigen p53Homo sapiens (human)Potency43.1857324
Chain A, JmjC domain-containing histone demethylation protein 3AHomo sapiens (human)Potency56.234111
Chain A, TYROSYL-DNA PHOSPHODIESTERASEHomo sapiens (human)Potency10.267313
chromobox protein homolog 1Homo sapiens (human)Potency56.234111
cytochrome P450 2C9, partialHomo sapiens (human)Potency6.922315
cytochrome P450 2D6Homo sapiens (human)Potency18.154313
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency12.635426
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency25.042417
DNA polymerase kappa isoform 1Homo sapiens (human)Potency19.952611
estrogen nuclear receptor alphaHomo sapiens (human)Potency39.6705844
estrogen receptor 2 (ER beta)Homo sapiens (human)Potency36.784926
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency45.1310966
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency35.638313
farnesoid X nuclear receptorHomo sapiens (human)Potency32.0500522
GVesicular stomatitis virusPotency6.922315
gemininHomo sapiens (human)Potency19.816723
GLI family zinc finger 3Homo sapiens (human)Potency26.2216318
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency37.2720518
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency28.328013
heat shock protein beta-1Homo sapiens (human)Potency50.7011220
Histone H2A.xCricetulus griseus (Chinese hamster)Potency119.856011
HLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)Potency6.922315
hypoxia-inducible factor 1 alpha subunitHomo sapiens (human)Potency57.951919
Inositol hexakisphosphate kinase 1Homo sapiens (human)Potency6.9223110
Interferon betaHomo sapiens (human)Potency6.922315
lamin isoform A-delta10Homo sapiens (human)Potency22.387211
lethal(3)malignant brain tumor-like protein 1 isoform IHomo sapiens (human)Potency14.125411
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency50.3627323
nuclear factor NF-kappa-B p105 subunit isoform 1Homo sapiens (human)Potency43.246713
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_aHomo sapiens (human)Potency39.5155215
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency29.9440334
parathyroid hormone/parathyroid hormone-related peptide receptor precursorHomo sapiens (human)Potency22.387211
peripheral myelin protein 22Rattus norvegicus (Norway rat)Potency26.556622
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency43.1462424
Peroxisome proliferator-activated receptor alphaHomo sapiens (human)Potency50.118711
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency20.324036
potassium voltage-gated channel subfamily H member 2 isoform dHomo sapiens (human)Potency19.952611
pregnane X nuclear receptorHomo sapiens (human)Potency21.8676337
pregnane X receptorRattus norvegicus (Norway rat)Potency28.3656111
progesterone receptorHomo sapiens (human)Potency28.6862216
RAR-related orphan receptor gammaMus musculus (house mouse)Potency45.2825230
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency44.1298319
retinoid X nuclear receptor alphaHomo sapiens (human)Potency23.5918424
serine-protein kinase ATM isoform aHomo sapiens (human)Potency39.810711
SMAD family member 2Homo sapiens (human)Potency23.769226
SMAD family member 3Homo sapiens (human)Potency23.769226
Spike glycoproteinSevere acute respiratory syndrome-related coronavirusPotency63.095711
TDP1 proteinHomo sapiens (human)Potency23.706924
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency46.6888329
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency0.595926
thyroid stimulating hormone receptorHomo sapiens (human)Potency33.5481434
thyrotropin-releasing hormone receptorHomo sapiens (human)Potency46.281911
USP1 protein, partialHomo sapiens (human)Potency50.340413
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency39.3145210
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency16.136148
vitamin D3 receptor isoform VDRAHomo sapiens (human)Potency44.668411
Voltage-dependent calcium channel gamma-2 subunitMus musculus (house mouse)Potency28.328013