Any animal metabolite produced during a metabolic reaction in corals (marine invertebrates).
ChEBI ID: 76498
| Member | Definition | Class |
|---|---|---|
| bufotenin | A tertiary amine that consists of N,N-dimethyltryptamine bearing an additional hydroxy substituent at position 5. | bufotenin |
| cembrene a | A fourteen-membered macrocyclic diterpene consisting of 1,5,9-trimethyl-12-(prop-1-en-2-yl)cyclotetradecane having three endocyclic double bonds located at positions 1, 5 and 9. | (R)-cembrene A |
| octadecyl palmitate | A palmitate ester resulting from the formal condensation of the carboxy group of palmitic acid with the hydroxy group of stearyl alcohol. | stearyl palmitate |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 334 (59.96) | 18.7374 |
| 1990's | 61 (10.95) | 18.2507 |
| 2000's | 64 (11.49) | 29.6817 |
| 2010's | 65 (11.67) | 24.3611 |
| 2020's | 33 (5.92) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 41 (6.34%) | 5.53% |
| Reviews | 39 (6.03%) | 6.00% |
| Case Studies | 24 (3.71%) | 4.05% |
| Observational | 3 (0.46%) | 0.25% |
| Other | 540 (83.46%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 30.9827 | 1 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 21.9341 | 1 | 1 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 66.9885 | 1 | 1 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 2.1177 | 1 | 1 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 3.1623 | 1 | 1 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 9.7328 | 2 | 2 |
| GLS protein | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 56.4407 | 2 | 2 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 110.3920 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 60.2071 | 1 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 53.6596 | 1 | 1 |
| polyprotein | Zika virus | Potency | 3.1623 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 53.2108 | 1 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 15.8644 | 3 | 3 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 40.8406 | 2 | 2 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 66.9885 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | Ki | 0.0251 | 1 | 1 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | Ki | 0.9100 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | Ki | 0.3800 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | Ki | 0.3800 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 0.0700 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | Ki | 0.3800 | 1 | 1 |
| 5-hydroxytryptamine receptor 7 | Rattus norvegicus (Norway rat) | Ki | 0.0079 | 1 | 1 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 11.4000 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | IC50 | 1.2000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | Kd | 0.0032 | 1 | 1 |