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catalyst
A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction.
ChEBI ID: 35223
Members (12)
Member | Definition | Class |
ferric sulfate | A compound of iron and sulfate in which the ratio of iron(3+) to sulfate ions is 3:2. | iron(3+) sulfate |
greigite | An iron sulfide mineral with formula Fe3S4. | greigite |
n,n,n',n'-tetramethylethylenediamine | An ethylenediamine derivative in which each nitrogen carries two methyl substituents. It is widely employed both as a ligand for metal ions and as a catalyst in organic polymerisation. | N,N,N',N'-tetramethylethylenediamine |
palladium chloride | A palladium coordination entity consisting of palladium(II) bound to two chlorine atoms. | palladium(II) chloride |
piperidine | An azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. It is a metabolite of cadaverine, a polyamine found in the human intestine. | piperidine |
platinum tetrachloride | A platinum coordination entity consisting of platinum(II) bound to two chlorine atoms. | platinum dichloride |
potassium carbonate | A potassium salt that is the dipotassium salt of carbonic acid. | potassium carbonate |
sulfuric acid | A sulfur oxoacid that consists of two oxo and two hydroxy groups joined covalently to a central sulfur atom. | sulfuric acid |
tempo | A member of the class of aminoxyls that is piperidine that carries an oxidanediyl group at position 1 and methyl groups at positions 2, 2, 6, and 6, respectively. | TEMPO |
tempol | A member of the class of aminoxyls that is TEMPO carrying a hydroxy substituent at position 4. It is a radical scavenger which exhibits anti-inflammatory and analgesic properties. | 4-hydroxy-TEMPO |
triethylenediamine | An organic heterobicylic compound that is piperazine with an ethane-1,2-diyl group forming a bridge between N1 and N4. It is typically used as a catalyst in polymerization reactions. | triethylenediamine |
zirconium chloride | A zirconium coordination entity comprising four chlorine atoms bound to a central zirconium atom. | zirconium tetrachloride |
Research
Studies (5,198)
Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
pre-1990 | 688 (13.24) | 18.7374 |
1990's | 495 (9.52) | 18.2507 |
2000's | 1,411 (27.15) | 29.6817 |
2010's | 2,162 (41.59) | 24.3611 |
2020's | 442 (8.50) | 2.80 |
Study Types
Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
Trials | 68 (1.24%) | 5.53% |
Reviews | 112 (2.05%) | 6.00% |
Case Studies | 73 (1.34%) | 4.05% |
Observational | 1 (0.02%) | 0.25% |
Other | 5,209 (95.35%) | 84.16% |
Protein Targets (28)
Potency Measurements
Inhibition Measurements
Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
Bile salt export pump | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
Carbonic anhydrase | Methanosarcina thermophila | Ki | 105,850.0000 | 1 | 2 |
Carbonic anhydrase | Methanothermobacter thermautotrophicus str. Delta H | Ki | 497,550.0000 | 1 | 2 |
Carbonic anhydrase | Stylophora pistillata | Ki | 330.0000 | 1 | 1 |
Carbonic anhydrase | Stylophora pistillata | Ki | 910.0000 | 1 | 1 |
Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 59,222.2222 | 8 | 9 |
Carbonic anhydrase 13 | Mus musculus (house mouse) | Ki | 267,000.0000 | 1 | 1 |
Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 197,200.0000 | 9 | 10 |
Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 20,666.6667 | 3 | 3 |
Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 453,333.5600 | 3 | 3 |
Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 340,000.3400 | 2 | 2 |
Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 9,900.0000 | 1 | 1 |
Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 1,380.0000 | 1 | 1 |
Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 154,000.0000 | 1 | 1 |
Proton-coupled amino acid transporter 1 | Homo sapiens (human) | Ki | 54,000.0000 | 1 | 1 |