A salt formally resulting from the reaction of hydrochloric acid with an organic base.
| Member | Definition | Role |
|---|
| (1R,2S)-tranylcypromine hydrochloride | A hydrochloride obtained by combining (1R,2S)-tranylcypromine with one equivalent of hydrochloric acid. | (1R,2S)-tranylcypromine hydrochloride |
| (2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzodioxan hydrochloride | A hydrochloride salt that is obtained by reaction of N-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine with one equivalent of hydrogen chloride. An alpha1A-adrenergic selective antagonist. | N-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine hydrochloride |
| (2R,3S)-EHNA hydrochloride | A hydrochloride salt obtained by reaction of (2R,3S)-EHNA with one equivalent of hydrochloric acid. Selective inhibitor of cGMP-stimulated phosphodiesterase (PDE2) (IC50 = 0.8 - 4 mM). Also a potent inhibitor of adenosine deaminase. | (2R,3S)-EHNA hydrochloride |
| (R)-fluoxetine hydrochloride | A hydrochloride obtained by reaction of (R)-fluoxetine with one equivalent of hydrochloric acid. | (R)-fluoxetine hydrochloride |
| (S)-fluoxetine hydrochloride | A hydrochloride obtained by reaction of (S)-fluoxetine with one equivalent of hydrochloric acid. | (S)-fluoxetine hydrochloride |
| 1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride | A hydrochloride salt that is obtained by reaction of 4-fluoro-N-{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl}benzamide with one equivalent of hydrogen chloride. Highly potent selective 5-HT1A receptor full agonist (pKi values are 9.0, 6.6, 7.5, 6.6 and < 6.0 for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT2 and 5-HT3 receptors respectively). Possibly binds between the agonist binding site and the G protein interaction switch site, affecting the activation mechanism, and may display positive cooperativity. Anxiolytic following central administration in vivo. | 4-fluoro-N-{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl}benzamide hydrochloride |
| 1-(2-(4-(4-fluoro-benzoyl)-piperidin-1-yl)-ethyl)-3,3-dimethyl-1,2-dihydro-indol-2-one | A hydrochloride resulting from the formal reation of equimolar amount of LY-310762 with hydrogen chloride. A potent and selective antagonist for the 5-hydroxytryptamine 1D (5-HT1D) receptor. | LY-310762 hydrochloride |
| 1-(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride | A hydrochloride salt prepared from anileridine and two molar equivalents of hydrogen chloride. | 1-(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride |
| 1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride | A hydrochloride salt that is obtained by reaction of 1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine with two equivalents of hydrogen chloride. Potent and selective inhibitor of dopamine uptake (KD = 5.5 nM in rat striatal membranes). | 1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride |
| 2-methyl-6-(phenylethynyl)pyridine hydrochloride | A hydrochloride salt obtained by reaction of 2-methyl-6-(phenylethynyl)pyridine with one equivalent of hydrochloric acid. Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw. | 2-methyl-6-(phenylethynyl)pyridine hydrochloride |
| 3,6-diamino-10-methylacridinium chloride hydrochloride | A hydrochloride resulting from the reaction of equimolar amounts of 3,6-diamino-10-methylacridinium chloride and hydrogen chloride. | 3,6-diamino-10-methylacridinium chloride.HCl |
| 5-chloro-6-(1-(2-iminopyrrolidinyl) methyl)uracil hydrochloride | A hydrochloride obtained by combining tipiracil with one equivalent of hydrochloric acid. Used in combination with trifluridine, a nucleoside metabolic inhibitor, for treatment of advanced/relapsed unresectable colorectal cancer. | tipiracil hydrochloride |
| a 77636 | A hydrochloride salt obtained by mixing equimolar amounts of (1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol with hydrochloric acid. Potent and selective dopamine D1-like receptor agonist (pEC50 values are 8.97 and < 5 for D1-like and D2-like receptors respectively). Displays anti-Parkinsonian activity following oral administration in vivo. | (1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol hydrochloride |
| acebutolol hydrochloride | The hydrochloride salt of acebutolol, prepared using equimolar amounts of acebutolol and hydrogen chloride. | acebutolol hydrochloride |
| acridine yellow | | acridine yellow |
| alo 2145 | The hydrochloride salt of apraclonidine. | apraclonidine hydrochloride |
| alosetron hydrochloride | The hydrochloride salt of alosetron. | alosetron hydrochloride |
| alprenolol hydrochloride | | alprenolol hydrochloride |
| amantadine hydrochloride | A hydrochloride obtained by combining amantadine and hydrochloric acid in equimolar amounts. | amantadine hydrochloride |
| amiloride hydrochloride, anhydrous | A hydrochloride obtained by combining amiloride with one molar equivalent of hydrochloric acid. | amiloride hydrochloride |
| aminolevulinic acid hydrochloride | A hydrochloride that is the monohydrochloride of 5-aminolevulinic acid. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp. | 5-aminolevulinic acid hydrochloride |
| amodiaquine hydrochloride | | amodiaquine hydrochloride |
| amperozide hydrochloride | The hydrochloride salt of amperozide. | amperozide hydrochloride |
| asl 8052 | The hydrochloride salt of esmolol. A cardioselective and short-acting beta1 receptor blocker with rapid onset but lacking intrinsic sympathomimetic and membrane-stabilising properties, it is used in the management of supraventricular arrhythmias, and for the control of hypertension and tachycardia during surgery. | esmolol hydrochloride |
| atomoxetine hydrochloride | The hydrochloride salt of atomoxetine. | atomoxetine hydrochloride |
| ay-20694 | | dexpropranolol hydrochloride |
| azelastine hydrochloride | The hydrochloride salt of azelastine. | azelastine hydrochloride |
| bacampicillin hydrochloride | The hydrochloride salt of bacampicillin. | bacampicillin hydrochloride |
| bambuterol hydrochloride | The hydrochloride salt of bambuterol. A long acting beta-adrenoceptor agonist used in the treatment of asthma, it is a prodrug for terbutaline. | bambuterol hydrochloride |
| benoxinate hydrochloride | The monohydrochloride salt of oxybuprocaine. | oxybuprocaine hydrochloride |
| benserazide hydrochloride | A hydrochloride that is the monohydrochloride salt of benserazide. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide hydrochloride has no antiparkinson actions when given alone. | benserazide hydrochloride |
| benzophenoneidum | A hydrochloride obtained by combining 4,4'-carbonimidoylbis(N,N-dimethylaniline) with one molar equivalent of hydrogen chloride. A fluorescent stain for demonstrating acid fast organisms in a method similar to the Ziehl Neelsen. It also can be used to make a fluorescent Schiff reagent. | auramine O |
| betaxolol hydrochloride | The hydrochloride salt of betaxolol. | betaxolol hydrochloride |
| biperiden hydrochloride | The hydrochloride salt of biperiden. A muscarinic antagonist affecting both the central and peripheral nervous systems, it is used in the treatment of all forms of Parkinson's disease. | biperiden hydrochloride |
| brl 15572 | A hydrochloride that is the monohydrochloride salt of 3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol. A selective h5-HT1D antagonist, displaying 60-fold selectivity over h5-HT1B, and exhibiting little or no affinity for a range of other receptor types. | 3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol hydrochloride |
| bromhexine hydrochloride | A hydrochloride resulting from the reaction of equimolar amounts of bromhexine and hydrogen chloride. It is used as a mucolytic for the treatment of respiratory disorders associated with productive cough (i.e. a cough characterised by the production of sputum). | bromhexine hydrochloride |
| bupivacaine hydrochloride | A hydrochloride obtained by combining 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide with one molar equivalent of hydrochloric acid. | 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide hydrochloride; bupivacaine hydrochloride (anhydrous) |
| buspirone hydrochloride | A hydrochloride salt resulting from the reaction of equimolar amounts of buspirone and hydrogen chloride. | buspirone hydrochloride |
| carteolol hydrochloride | | carteolol hydrochloride |
| cerm-1978 | The hydrochloride of bepridil. | bepridil hydrochloride |
| chlorpromazine hydrochloride | The hydrochloride salt of chlorpromazine. | chlorpromazine hydrochloride |
| ci 906 | A hydrochloride resulting from the reaction of equimolar amounts of quinapril and hydrogen chloride. A prodrug for quinaprilat hydrochloride (by hydrolysis of the ethyl ester to the corresponding carboxylic acid), it is used as an angiotensin-converting enzyme inhibitor (ACE inhibitor) for the treatment of hypertension and congestive heart failure. | quinapril hydrochloride |
| cinacalcet hydrochloride | A hydrochloride derived from equimolar amounts of cinacalcet and hydrogen chloride. | cinacalcet hydrochloride |
| ciprofloxacin hydrochloride anhydrous | The anhydrous form of the monohydrochloride salt of ciprofloxacin. | ciprofloxacin hydrochloride (anhydrous) |
| cis-flupenthixol dihydrochloride | The dihydrochloride salt of cis-flupenthixol. | cis-flupenthixol dihydrochloride |
| clomipramine hydrochloride | A hydrochloride resulting from the reaction of equimolar amounts of clomipramine and hydrogen chloride. One of the more sedating tricyclic antidepressants, it is used for the treatment of depression as well as obsessive-compulsive disorder and phobias. | clomipramine hydrochloride |
| cocaine hydrochloride | The hydrochloride salt of cocaine. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. | cocaine hydrochloride |
| cordium | The hydrochloride monohydrate of bepridril. | bepridil hydrochloride monohydrate |
| corlanor | A hydrochloride obtained by combining ivabradine with one molar equivalent of hydrochloric acid. Used to treat patients with angina who have intolerance to beta blockers and/or heart failure. | ivabradine hydrochloride |
| cyclizine hydrochloride | A hydrochloride salt consisting of equimolar amounts of cyclizine and hydrogen chloride. | cyclizine hydrochloride |
| cyclobenzaprine hydrochloride | The hydrochloride salt of cyclobenzaprine. A centrally acting skeletal muscle relaxant, it is used in the symptomatic treatment of painful muscle spasm. | cyclobenzaprine hydrochloride |
| cycloguanil hydrochloride | The hydrochloride salt of cycloguanil. | cycloguanil hydrochloride |
| cyproheptadine hydrochloride (anhydrous) | The hydrochloride salt of cyproheptadine. Note that the drug named cyproheptadine hydrochloride generally refers to cyproheptadine hydrochloride sesquihydrate. | cyproheptadine hydrochloride (anhydrous) |
| desipramine hydrochloride | The hydrochloride salt of desipramine. | desipramine hydrochloride |
| dicyclomine hydrochloride | The hydrochloride salt of dicyclomine. An anticholinergic, it is used to treat or prevent spasm in the muscles of the gastrointestinal tract, particularly that associated with irritable bowel syndrome. | dicyclomine hydrochloride |
| diethylpropion hydrochloride | The hydrochloride salt of diethylpropion. A central stimulant and indirect-acting sympathomimetic, it is an appetite depressant and is used as an anoretic in the short term management of obesity. | diethylpropion hydrochloride |
| diltiazem hydrochloride | A hydrochloride salt resulting from the reaction of equimolar amounts of diltiazem and hydrogen chloride. A calcium-channel blocker and vasodilator, it is used in the management of angina pectoris and hypertension. | diltiazem hydrochloride |
| diphenhydramine hydrochloride | The hydrochloride salt of diphenhydramine. | diphenhydramine hydrochloride |
| diphenoxylate hydrochloride | The hydrochloride salt of diphenoxylate. | diphenoxylate hydrochloride |
| diphenylpyraline hydrochloride | The hydrochloride salt of diphenylpyraline. A sedating antihistamine, it is used as the hydrochloride for the symptomatic relief of allergic conditions including rhinitis and hay fever, and in pruritic skin disorders. | diphenylpyraline hydrochloride |
| dipivefrin hydrochloride | The hydrochloride salt of dipivefrin. It is used topically as eye drops to reduce intra-ocular pressure in the treatment of open-angle glaucoma or ocular hypertension. | dipivefrin hydrochloride |
| dobutamine hydrochloride | The hydrochloride salt of dobutamine. A beta1-adrenergic receptor agonist that has cardiac stimulant action without evoking vasoconstriction or tachycardia, it is used to increase the contractility of the heart in the management of acute heart failure. | dobutamine hydrochloride |
| doxapram hydrochloride | The hydrochloride salt of doxapram. A central and respiratory stimulant with a brief duration of action, both doxapram hydrochloride and its hydrate are used as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering. | doxapram hydrochloride (anhydrous) |
| dyclonine hydrochloride | The hydrochloride salt of dyclonine. | dyclonine hydrochloride |
| eflornithine hydrochloride | The hydrochloride and hydrate of the trypanocidal drug eflornithine. | eflornithine hydrochloride monohydrate |
| emetine dihydrochloride | The dihydrochloride salt of emetine. | emetine dihydrochloride |
| epinastine hydrochloride | | epinastine hydrochloride |
| eprazinone hydrochloride | A hydrochloride obtained by combining eprazinone with two molar equivalents of hydrochloric acid. | eprazinone hydrochloride |
| erlotinib hydrochloride | The hydrochloride salt of erlotinib. | erlotinib hydrochloride |
| ethambutol hydrochloride | The dihydrchloride salt of ethambutol. A bacteriostatic antimycobacterial drug, it is effective against Mycobacterium tuberculosis and some other mycobacteria. It is used in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of M. tuberculosis are readily produced if ethambutol dihydrochloride is used alone. | ethambutol dihydrochloride |
| fasudil hydrochloride | A hydrochloride obtained by reaction of fasudil with one equivalent of hydrochloric acid. | fasudil hydrochloride |
| fingolimod hydrochloride | The hydrochloride salt of 2-amino-2-[2-(4-octylphenyl) ethyl]-1,3-propanediol (fingolimod). | fingolimod hydrochloride |
| flavoxate hydrochloride | The hydrochloride salt of flavoxate. | flavoxate hydrochloride |
| fluoxetine hydrochloride | | N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]-1-propanamine hydrochloride (1:1) |
| gemcitabine hydrochloride | A 2'-deoxycytidine hydrochloriode having geminal fluoro substituents in the 2'-position. An inhibitor of ribonucleotide reductase, gemcitabine hydrochloride is used in the treatment of various carcinomas, including non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer. | gemcitabine hydrochloride |
| glycinexylidide monohydrochloride | The hydrochloride salt of glycinexylidide. | glycinexylidide hydrochloride |
| GR 127935 hydrochloride | A hydrochloride obtained by reaction of GR 127935 with one equivalent of hydrochloric acid. Potent and selective 5-HT1B/1D receptor antagonist (pKi values are 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptors). Displays > 100-fold selectivity over 5HT1A, 5-HT2A, 5-HT2C receptors and other receptor types. Centrally active following oral administration. | GR 127935 hydrochloride |
| GS4012 | A hydrochloride obtained by combining the free base of GS4012 with one molar equivalent of hydrochloric acid. | GS4012 |
| hmr 1275 | A hydrochloride salt resulting from the formal reaction of equimolar amounts of alvocidib and hydrogen chloride. A cyclin-dependent kinase 9 (CDK9) inhibitor, it has been studied for the treatment of acute myeloid leukaemia, arthritis and atherosclerotic plaque formation. | alvocidib hydrochloride |
| hydralazine hydrochloride | The hydrochloride salt of hydralazine; a direct-acting vasodilator that is used as an antihypertensive agent. | hydralazine hydrochloride |
| imipramine hydrochloride | | imipramine hydrochloride |
| irinotecan hydrochloride | A hydrochloride obtained by combining irinotecan with one molar equivalent of hydrochloric acid. Used (in the form of its trihydrate) in combination with fluorouracil and leucovorin, for the treatment of patients with metastatic adenocarcinoma of the pancreas after disease progression following gemcitabine-based therapy. It is converted via hydrolysis of the carbamate linkage to its active metabolite, SN-38, which is ~1000 times more active. | irinotecan hydrochloride (anhydrous) |
| jte 607 | The dihydrochloride salt of JTE-607. It is a cytokine inhibitor which suppresses the production of proinflammatory cytokines such as interleukin (IL-1beta), IL-6, IL-8, granulocyte macrophage colony stimulating factor (GM-CSF), and tumor necrosis factor (TNF-alpha). It acts as a pro-drug which is cleaved by carboxylesterase 1 (CES1) to its active free acid form, which then binds to cleavage and polyadenylation specificity factor 3 (CPSF3). | JTE-607 dihydrochloride |
| l 671152 | The hydrochloride salt of dorzolamide. It is used in ophthalmic solutions to lower increased intraocular pressure in the treatment of open-angle glaucoma and ocular hypertension. | dorzolamide hydrochloride |
| l 778,123 | The hydrochloride salt of L-778,123. It is a dual inhibitor of FPTase and GGPTase-I (IC50 of 2nM and 98nm, respectively) and exhibits anti-cancer properties. | L-778,123 hydrochloride |
| levobunolol hydrochloride | A hydrochloride obtained by combining equimolar amounts of levobunolol and hydrochloric acid. A non-selective beta-adrenergic antagonist used for treatment of glaucoma. | levobunolol hydrochloride |
| lidocaine hydrochloride | The anhydrous form of the hydrochloride salt of lidocaine. | lidocaine hydrochloride |
| lofepramine hydrochloride | | lofepramine hydrochloride |
| lomefloxacin hydrochloride | The hydrochloride salt of lomefloxacin. It is administered by mouth to treat bacterial infections including bronchitis and urinary tract infections. It is also used topically as eye drops for the treatment of bacterial conjunctivitis, and as ear drops for the treatment of otitis externa and otitis media. | lomefloxacin hydrochloride |
| loperamide hydrochloride | A hydrochloride obtained by combining loperamide with one equivalent of hydrochloric acid. Used for treatment of diarrhoea resulting from gastroenteritis or inflammatory bowel disease. | loperamide hydrochloride |
| lotensin | A hydrochloride salt resulting from the reaction of benazepril with 1 mol eq. of hydrogen chloride. It is used as a prodrug for angiotensin-converting enzyme inhibitor benazeprilat in the treatment of hypertension and heart failure. | benazepril hydrochloride |
| lurasidone hydrochloride | A hydrochloride obtained by reaction of lurasidone with one equivalent of hydrochloric acid. An atypical antipsychotic agent used for the treatment of schizophrenia. | lurasidone hydrochloride |
| mechlorethamine hydrochloride | The hydrochloride salt of mechlorethamine. | mechlorethamine hydrochloride |
| medetomidine hydrochloride | | medetomidine hydrochloride |
| mefloquine hydrochloride | | Mefloquine hydrochloride |
| memantine hydrochloride | A hydrochloride obtained by reaction of memantine with one equivalent of hydrochloric acid. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels. | memantine hydrochloride |
| meperidine hydrochloride | The hydrochloride salt of pethidine. An analgesic used for the treatment of postoperative and labour pain. | pethidine hydrochloride |
| mepivacaine hydrochloride | The hydrochloride salt of mepivacaine. It is used as a local anaesthetic. | mepivacaine hydrochloride |
| metformin hydrochloride | A hydrochloride resulting from the reaction of metformin with one molar equivalent of hydrogen chloride. | metformin hydrochloride |
| methapyrilene hydrochloride | A hydrochloride that is the monohydrochloride salt of methapyrilene. | methapyrilene hydrochloride |
| methixene hydrochloride | | methixene hydrochloride |
| methoctramine | A hydrochloride obtained by combining methoctramine with four molar equivalents of hydrochloric acid. | methoctramine tetrahydrochloride |
| methyl 5-aminolevulinate hydrochloride | The hydrochloride salt of methyl 5-aminolevulinate. A prodrug, it is metabolised to protoporphyrin IX, a photosensitizer, and is used in the photodynamic treatment of non-melanoma skin cancer (including basal cell carcinoma). Topical application results in an accumulation of protoporphyrin IX in the skin lesions to which the cream has been applied. Subsequent illumination with red light results in the generation of toxic singlet oxygen that destroys cell membranes and thereby kills the tumour cells. | methyl 5-aminolevulinate hydrochloride |
| mexiletine hydrochloride | A hydrochloride composed of equimolar amounts of mexiletine and hydrogen chloride. | mexiletine hydrochloride |
| mianserin hydrochloride | The hydrochloride salt of mianserin, a tetracyclic compound with antidepressant effects. | mianserin hydrochloride |
| midazolam hydrochloride | The hydrochloride salt of midazolam. | midazolam hydrochloride |
| midodrine hydrochloride | A hydrochloride resulting from the combination of equimolar amounts of midodrine and hydrogen chloride. Midodrine is a direct-acting sympathomimetic with selective alpha-adrenergic agonist activity. The hydrochloride salt is used as a peripheral vasoconstrictor in the treatment of certain hypotensive states. The main active moiety is its major metabolite, deglymidodrine. | midodrine hydrochloride |
| minaprine dihydrochloride | | minaprine hydrochloride |
| mitoxantrone hydrochloride | | mitoxantrone dihydrochloride |
| mk 458 | The hydrochloride salt of naxagolide. | naxagolide hydrochloride |
| moricizine hydrochloride | A hydrochloride salt obtained from equimola amounts of moricizine and hydrogen chloride. | moricizine hydrochloride |
| morphine chloride | The hydrochloride salt of morphine. | morphine hydrochloride |
| moxifloxacin hydrochloride | A hydrochloride comprising equimolar amounts of moxifloxacin and hydrogen chloride. | moxifloxacin hydrochloride |
| n-(1-naphthyl)ethylenediamine dihydrochloride | An ethylenediamine dihydrochloride compound having an N-(1-naphthyl) substituent. | N-(1-naphthyl)ethylenediamine dihydrochloride |
| n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride | An aromatic ether that is (2-phenoxyethyl)benzene which carries a 2-(dipropylamino)ethyl group at position 3 and a methoxy group at position 6. It is a potent and selective sigma1 receptor antagonist. | N-{2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl}-N-propylpropan-1-amine hydrochloride |
| n,n'-dibenzhydrylethane-1,2-diamine dihydrochloride | A hydrochloride obtained by combining N,N'-bis(diphenylmethyl)ethane-1,2-diamine with two molar equivalent of hydrochloric acid. | AMN082 dihydrochloride |
| nab-365 | A hydrochloride that is the monohydrochloride salt of clenbuterol. | clenbuterol hydrochloride |
| naftifine hydrochloride | | Naftifine hydrochloride |
| nalbuphine hydrochloride | | nalbuphine hydrochloride |
| naloxone hydrochloride | A hydrochloride resulting from the formal reaction of equimolar amounts of naloxone and hydrogen chloride. A specific opioid antagonist, it is used to reverse the effects of opioids, both following their use of opioids during surgery and in cases of known or suspected opioid overdose. | naloxone hydrochloride |
| naltrexone hydrochloride | A hydrochloride obtained by reaction of oxycodone with one molar equivalent of hydrochloric acid. it is a mu-opioid receptor antagonist that is used to treat alcohol dependence. | naltrexone hydrochloride |
| naratriptan hydrochloride | | Naratriptan hydrochloride |
| nebivolol hydrochloride | A hydrochloride obtained by reaction of (R,S,S,S)-nebivolol with one equivalent of hydrochloric acid. | (R,S,S,S)-nebivolol hydrochloride |
| nefazodone hydrochloride | | nefazodone hydrochloride |
| neutral red | A hydrochloride obtained by combining the free base of neutral red with one equivalent of hydrochloric acid. Neutral red acts as a pH indicator, changing from red to yellow between pH 6.8 and 8.0. | neutral red |
| new fuchsin | A hydrochloride that is the monohydrochloride of 4-[(4-aminophenyl)(4-iminocyclohexa-2,5-dien-1-ylidene)methyl]-2-methylaniline. One of the minor constituents of Basic fuchsin, together with pararosanilin, rosanilin and magenta II. | new fuchsin |
| ng-nitroarginine methyl ester | A hydrochloride obtained by combining N(gamma)-nitro-L-arginine methyl ester with one equivalent of hydrochloric acid. | N(gamma)-nitro-L-arginine methyl ester hydrochloride |
| nimustine | A hydrochloride obtained by combining nimustine with one equivalent of hydrochloric acid. An antineoplastic agent especially effective against malignant brain tumors. | nimustine hydrochloride |
| nnc 55-0396 | The dihydrochloride salt of NNC 55-0396. It is a stable analogue of mibefradil and a highly selective T-type calcium channel blocker. | NNC 55-0396 dihydrochloride |
| nsc 23766 | A hydrochloride resulting from the formal reaction of NSC 23766 with 3 mol eq. of hydrogen chloride. An inhibitor of the signalling G-protein known as RAC1 (Ras-related C3 botulinum toxin substrate 1). | NSC 23766 trihydrochloride |
| nsc-145,668 | A hydrochloride salt resulting from the reaction of equimolar amounts of ancitabine and hydrogen chloride. | ancitabine hydrochloride |
| orphenadrine hydrochloride | A hydrochloride comprising equimolar amounts of ophenadrine and hydrogen chloride. | orphenadrine hydrochloride |
| oxybutynin hydrochloride | | oxybutynin chloride |
| oxymetazoline hydrochloride | A hydrochloride salt resulting from the reaction of equimolar quantities of oxymetazoline and hydrogen chloride. A direct-acting sympathomimetic with marked alpha-adrenergic activity, it is a vasoconstrictor that is used to relieve nasal congestion. | oxymetazoline hydrochloride |
| paroxetine hydrochloride | The hydrochloride salt of paroxetine. It is an antidepressant drug. | paroxetine hydrochloride |
| pf-670462 | A hydrochloride salt resulting from the formal reaction of 3-[(3-chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine with 2 mol eq. of hydrogen chloride. It is a selective inhibitor of the delta- and epsilon-isoforms of casein kinase 1 (CK1delta and CK1epsilon). | PF-670462 |
| phenazopyridine hydrochloride | A hydrochloride obtained by combining phenazopyridine with one equivalent of hydrochloric acid. A local anesthetic that has topical analgesic effect on mucosa lining of the urinary tract. Its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity. | phenazopyridine hydrochloride |
| phenylephrine hydrochloride | A hydrochloride that is the monohydrochloride salt of phenylephrine. | phenylephrine hydrochloride |
| phenylhydrazine hydrochloride | A hydrochloride resulting from the reaction of equimolar amounts of phenylhydrazine and hydrogen chloride. | phenylhydrazine hydrochloride |
| pibutidine hydrochloride | The hydrochloride salt of pibutidine. It is a H2 receptor antagonist which was developed for the treatment of peptic ulcers and duodenal ulcers. It was in phase III clinical trials in Japan (now discontinued). | pibutidine hydrochloride |
| pilocarpine hydrochloride | The hydrochloride salt of (+)-pilocarpine, a medication used to treat increased pressure inside the eye and dry mouth. | pilocarpine hydrochloride |
| pipamperone dihydrochloride | A hydrochloride resulting from the reaction of pipamperone with 2 mol eq. of hydrogen chloride. It is used as an antipsychotic. | pipamperone dihydrochloride |
| pirenzepine dihydrochloride | | pirenzepine hydrochloride |
| pivmecillinam hydrochloride | | pivmecillinam hydrochloride |
| prazosin hydrochloride | | prazosin hydrochloride |
| prilocaine hydrochloride | The monohydrochloride salt of prilocaine. | prilocaine hydrochloride |
| procainamide hydrochloride | A hydrochloride which has procainamide as the amino component. | procainamide hydrochloride |
| procarbazine hydrochloride | A hydrochloride obtained by combining procarbazine with one equivalent of hydrochloric acid. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands. | procarbazine hydrochloride |
| procyclidine hydrochloride | | procyclidine hydrochloride |
| profenamine hydrochloride | The monohydrochloride salt of profenamine. An antimuscarinic, it is used for the symptomatic treatment of Parkinson's disease. | profenamine hydrochloride |
| promazine hydrochloride | | promazine hydrochloride |
| promethazine hydrochloride | The hydrochloride salt of promethazine. | promethazine hydrochloride |
| propafenone hydrochloride | A hydrochloride that is the monohydrochloride salt of propafenone. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used in the management of supraventricular and ventricular arrhythmias. | propafenone hydrochloride |
| propranolol hydrochloride | | propranolol hydrochloride |
| protriptyline hydrochloride | | protriptyline hydrochloride |
| pseudoephedrine hydrochloride | A hydrochloride that is the monohydrochloride salt of pseudoephedrine. | pseudoephedrine hydrochloride |
| pyridoxamine dihydrochloride | A hydrochloride obtained by combining pyridoxamine with two molar equivalents of hydrochloric acid. Used for treatment of diabetic nephropathy. | pyridoxamine dihydrochloride |
| pyridoxine hydrochloride | The hydrochloride salt of pyridoxine. | pyridoxine hydrochloride |
| quinacrine mustard | | quinacrine mustard dihydrochloride |
| raloxifene hydrochloride | A hydrochloride salt resulting from the reaction of equimolar amounts of raloxifene and hydrogen chloride. | raloxifene hydrochloride |
| ranitidine hydrochloride | | ranitidine hydrochloride |
| ropivacaine | The anhydrous form of (S)-ropivacaine hydrochloride. | (S)-ropivacaine hydrochloride (anhydrous) |
| rs 25259-197 | A hydrochloride obtained by combining palonosetron with one molar equivalent of hydrogen chloride; an antiemetic used in combination with netupitant (under the trade name Akynzeo) to treat nausea and vomiting in patients undergoing cancer chemotherapy. | palonosetron hydrochloride |
| rs 39604 | A hydrochloride salt obtained by mixing equimolar amounts of RS 39604 with hydrochloric acid. A potent and selective 5-HT4 antagonist, with a pKi of 9.1 at 5-HT4 receptors in guinea pig striatal membranes and greater than 1000-fold selectivity over 5-HT1A, 2C, 3 and D1, D2, M1, M2, AT1, B1 and alpha1C receptors. The ketone group gives RS 39604 a relatively long half life; it is also orally active and so suitable for in vivo studies. | RS 39604 hydrochloride |
| sapropterin dihydrochloride | The dihydrochloride salt of sapropterin. It is used for the diagnosis and treatment of variant forms of phenylketonuria (hyperphenylalaninaemia) associated with tetrahydrobiopterin deficiency. Natural cofactor for phenylalanine hydroxylase, tyrosine hydroxylase, tryptophan hydroxylase, and nitric oxide synthetase. | sapropterin dihydrochloride |
| selegiline hydrochloride, (r)-isomer | | selegiline hydrochloride |
| sertraline hydrochloride | A hydrochloride resulting from the reaction of equimolar amounts of sertraline and hydrogen chloride. A selective serotonin-reuptake inhibitor (SSRI), it is administered orally as an antidepressant for the treatment of depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder. | sertraline hydrochloride |
| siquil | | triflupromazine hydrochloride |
| sotalol hydrochloride | A hydrochloride salt that is the monohydrochloride of sotalol. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias. | sotalol hydrochloride |
| spectinomycin dihydrochloride | A hydrochloride obtained by combining spectinomycin with two molar equivalents of hydrochloric acid. An antibiotic that is active against gram-negative bacteria and used (as its pentahydrate) to treat gonorrhea. | spectinomycin dihydrochloride |
| talampicillin hydrochloride | | talampicillin hydrochloride |
| tamsulosin hydrochloride | A hydrochloride resulting from the reaction of equimolar amounts of tamulosin and hydrogen chloride. | tamsulosin hydrochloride |
| terbinafine hydrochloride | A hydrochloride obtained by reaction of terbinafine with one molar equivalent of hydrogen chloride. | terbinafine hydrochloride |
| tetrahydrozoline hydrochloride | The hydrochloride salt of tetryzoline. It is used as a nasal decongestant. | tetrahydrozoline hydrochloride |
| thiamine hydrochloride | A hydrochloride obtained by combining thiamine chloride with one molar equivalent of hydrochloric acid. | thiamine hydrochloride |
| thioridazine hydrochloride | | thioridazine hydrochloride |
| tiagabine hydrochloride | A hydrochloride resulting from the reaction of equimolar amounts of tiagabine and hydrogen chloride. A GABA reuptake inhibitor, it is used for the treatment of epilepsy. | tiagabine hydrochloride |
| ticlopidine hydrochloride | | ticlopidine hydrochloride |
| tirofiban hydrochloride | | tirofiban hydrochloride |
| tramadol hydrochloride | A hydrochloride resulting from the reaction of (R,R)-tramadol with 1 molar equivalent of hydrogen chloride; the (R,R)-enantiomer of the racemic opioid analgesic tramadol hydrochloride, it exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer. | (R,R)-tramadol hydrochloride |
| trazodone hydrochloride | A hydrochloride salt prepared from equimolar amounts of trazodone and hydrogen chloride. | trazodone hydrochloride |
| trifluoperazine hydrochloride | | trifluoperazine hydrochloride |
| triprolidine hydrochloride anhydrous | A hydrochloride resulting from the formal reaction of equimolar amounts of triprolidine and hydrogen chloride. Its monohydrate is used for the symptomatic relief of uticaria, rhinitis, and various pruritic skin disorders. | triprolidine hydrochloride (anh.) |
| u 18666a | A hydrochloride obtained by reaction of 3beta-(2-diethylaminoethoxy)androst-5-en-17-one with one equivalent of hydrochloric acid. It is a cholesterol synthesis and transport inhibitor. | 3beta-(2-diethylaminoethoxy)androst-5-en-17-one hydrochloride |
| uroxatral | | alfuzosin hydrochloride |
| vanoxerine | A hydrochloride salt that is obtained by reaction of vanoxerine with two equivalents of hydrogen chloride. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration. | vanoxerine dihydrochloride |
| venlafaxine hydrochloride | | venlafaxine hydrochloride |
| vilazodone hydrochloride | A hydrochloride obtained by reaction of vilazodone with one equivalent of hydrochloric acid. Used for the treatment of major depressive disorder. | vilazodone hydrochloride |
| ziprasidone hydrochloride | The hydrochloride hydrate salt of ziprasidone. | ziprasidone hydrochloride hydrate |
| zm 252868 | A hydrochloride obtained by combining PD-153035 with one equivalent of hydrochloric acid. | PD-153035 hydrochloride |