Any metabolite (endogenous or exogenous) found in human blood serum samples.
| Member | Definition | Class |
|---|
| 1-hydroxymethylmidazolam | An imidazobenzodiazepine that is midazolam in which one of the hydrogens of the methyl group is substituted by a hydroxy group. It is the major metabolite of the anesthetic, midazolam. | 1-hydroxymidazolam |
| 1-hydroxymethylmidazolam glucuronide | A beta-D-glucosiduronic acid that is beta-D-glucuronic acid in which the anomeric hydroxyl hydrogen has been replaced by a 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepin-4-yl group. It is the glucuronidated conjugate of the midazolam metabolite, 1-hydroxymidazolam. | 1-hydroxymidazolam beta-D-glucuronide |
| 1,3,7-trimethylurate | An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8, and the nitrogens at positions 1, 3, and 7 are substituted by methyl groups. It is a metabolite of caffeine. | 1,3,7-trimethyluric acid |
| 1,7-dimethylxanthine | A dimethylxanthine having the two methyl groups located at positions 1 and 7. It is a metabolite of caffeine and theobromine in animals. | 1,7-dimethylxanthine |
| 20-carboxyleukotriene b4 | A member of the class of leukotrienes that is leukotriene B4 in which the terminal methyl group has undergone formal oxidation to the corresponding carboxylic acid. | 20-hydroxy-20-oxoleukotriene B4 |
| 21-deoxycortisol | A deoxycortisol that is 17xi-pregn-4-ene-3,20-dione substituted by a beta-hydroxy group at position 11 and an alpha-hydroxy group at position 17. It is a marker of virilizing adrenal hyperplasia caused by 21-hydroxylase deficiency. | 21-deoxycortisol |
| 24-hydroxycholesterol | A 24-hydroxycholesterol that has S configuration at position 24. It is the major metabolic breakdown product of cholesterol in the brain. | (24S)-24-hydroxycholesterol |
| 3-hydroxyglutaric acid | A 3 hydroxy carboxylic acid that is glutaric acid which is substituted by a hydroxy group at position 3. It is a diagnostic marker for glutaric aciduria type I. | 3-hydroxyglutaric acid |
| 3-methoxytyramine | A monomethoxybenzene that is dopamine in which the hydroxy group at position 3 is replaced by a methoxy group. It is a metabolite of the neurotransmitter dopamine and considered a potential biomarker of pheochromocytomas and paragangliomas. | 3-methoxytyramine |
| 4-hexanolide | A gamma-lactone that is oxolan-2-one substituted by an ethyl group at position 5. | gamma-caprolactone |
| 4-hydroxyhippuric acid | An N-acylglycine that is the 4-hydroxy derivative of hippuric acid. | p-hydroxyhippuric acid |
| 4-hydroxymidazolam | An imidazobenzodiazepine that is midazolam which is substituted by a hydroxy group at position 4. It is the minor hydroxylated metabolite of the anesthetic, midazolam. | 4-hydroxymidazolam |
| 7-oxodehydroepiandrosterone | A 3beta-hydroxy-Delta(5)-steroid that is dehydroepiandrosterone carrying an additional oxo group at position 7. | 7-ketodehydroepiandrosterone |
| 9,10,13-trihydroxy-11-octadecenoic acid | A TriHOME that is (11E)-octadec-11-enoic acid in which the three hydroxy substituents are located at positions 9, 10 and 13. | 9,10,13-TriHOME |
| acetaminophen | A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group. | paracetamol |
| acetyltaurine | An amino sulfonic acid that is taurine substituted by an acetyl group at the N atom. | acetyltaurine |
| alpha-ketocaproic acid | A straight-chain fatty acid consisting of hexanoic acid having an oxo group at position 2. | 2-oxohexanoic acid |
| anandamide | An N-acylethanolamine 20:4 resulting from the formal condensation of carboxy group of arachidonic acid with the amino group of ethanolamine. | anandamide |
| androsterone | An androstanoid that is 5alpha-androstane having a hydroxy substituent at the 3alpha-position and an oxo group at the 17-position. It is a metabolite of dehydroepiandrosterone . | androsterone |
| apelin-12 peptide | A 12 amino acid oligopeptide fragment of apelin-13 lacking the terminal L-phenylalanine residue. | apelin-12 |
| aspartyl-phenylalanine | A dipeptide formed from L-alpha-aspartyl and L-phenylalanine residues. It is obtained after the hydrolysis of aspartame in intestinal lumen. | Asp-Phe |
| bradykinin | A linear nonapeptide messenger belonging to the kinin group of proteins, with amino acid sequence RPPGFSPFR. Enzymatically produced from kallidin in the blood, it is a powerful vasodilator that causes smooth muscle contraction, and may mediate inflammation. | bradykinin |
| caffeine | A trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7. A purine alkaloid that occurs naturally in tea and coffee. | caffeine |
| caprolactam | A member of the class of caprolactams that is azepane substituted by an oxo group at position 2. | epsilon-caprolactam |
| deoxycholic acid | A bile acid that is 5beta-cholan-24-oic acid substituted by hydroxy groups at positions 3 and 12 respectively. | deoxycholic acid |
| dopamine 3-o-sulfate | An aryl sulfate that is dopamine in which the phenolic hydrogen at position 3 has been replaced by a sulfo group. | dopamine 3-O-sulfate zwitterion; dopamine 3-O-sulfate |
| dopamine 3-o-sulfate | A zwitterion obtained by transfer of a proton from the sulfonyl to the amino group of dopamine 3-O-sulfate; major species at pH 7.3. | dopamine 3-O-sulfate zwitterion; dopamine 3-O-sulfate |
| dopamine 4-o-sulfate | An aryl sulfate that is dopamine in which the phenolic hydrogen at position 4 has been replaced by a sulfo group. | dopamine 4-O-sulfate zwitterion; dopamine 4-O-sulfate |
| dopamine 4-o-sulfate | A zwitterion obtained by transfer of a proton from the sulfonyl to the amino group of dopamine 4-O-sulfate; major species at pH 7.3. | dopamine 4-O-sulfate zwitterion; dopamine 4-O-sulfate |
| epietiocholanolone | A 3beta-hydroxy steroid that is 5beta-androstane substituted by a hydroxy group at position 3beta and an oxo group at position 17. It is a metabolite of testosterone. | epietiocholanolone |
| ethyl arachidonate | A long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of arachidonic acid with the hydroxy group of ethanol. | ethyl arachidonate |
| glycoursodeoxycholic acid | A bile acid glycine conjugate derived from ursoodeoxycholic acid. | glycoursodeoxycholic acid |
| hippuric acid | An N-acylglycine in which the acyl group is specified as benzoyl. | N-benzoylglycine |
| histidyl-proline diketopiperazine | A homodetic cyclic peptide resulting from the formal condensation of both the amino and acid groups of L-histidine with the acid and amino groups of L-proline. It is a metabolite of thyrotropin-releasing hormone (TRH). | cyclo(L-His-L-Pro) |
| kaempferol | A tetrahydroxyflavone in which the four hydroxy groups are located at positions 3, 5, 7 and 4'. Acting as an antioxidant by reducing oxidative stress, it is currently under consideration as a possible cancer treatment. | kaempferol |
| menaquinone 7 | A menaquinone whose side-chain contains seven isoprene units in an all-trans-configutation. | menaquinone-7 |
| n-myristoylglycine | An N-acylglycine in which the acyl group is specified as myristoyl (tetradecanoyl). | N-myristoylglycine |
| n-palmitoylsphingosine | A N-acylsphingosine in which the ceramide N-acyl group is specified as hexadecanoyl (palmitoyl). | N-hexadecanoylsphingosine |
| palmitoleic acid | A hexadec-9-enoic acid in which the double bond at position C-9 has cis configuration. | palmitoleic acid |
| pantothenic acid | A pantothenic acid having R-configuration. | (R)-pantothenic acid |
| pentadecanoic acid | A straight-chain saturated fatty acid containing fifteen-carbon atoms. | pentadecanoic acid |
| phenylalanylphenylalanine | A dipeptide formed from two L-phenylalanine residues. | Phe-Phe zwitterion; Phe-Phe |
| piperine | A N-acylpiperidine that is piperidine substituted by a (1E,3E)-1-(1,3-benzodioxol-5-yl)-5-oxopenta-1,3-dien-5-yl group at the nitrogen atom. It is an alkaloid isolated from the plant Piper nigrum. | piperine |
| propranolol | A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3. | propranolol |
| ribavirin 5'-diphosphate | A 1-ribosyltriazole that is ribavirin in which the hydroxy group at the 5'-position is replaced by a phosphonooxy group. It is the active metabolite of the antiviral agent ribavirin. | ribavirin 5'-monophosphate |
| ribavirin 5'-triphosphate | A 1-ribosyltriazole that is ribavirin in which the hydroxy group at the 5'-position is replaced by a triphosphate group. It is the active metabolite of the antiviral agent ribavirin. | ribavirin 5'-triphosphate |
| stachydrine | An amino acid betaine that is L-proline zwitterion in which both of the hydrogens attached to the nitrogen are replaced by methyl groups. | L-proline betaine |
| theobromine | A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator. | theobromine |
| theophylline | A dimethylxanthine having the two methyl groups located at positions 1 and 3. It is structurally similar to caffeine and is found in green and black tea. | theophylline |
| u 62840 | | treprostinil |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 22.0164 | 1 | 2 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 8.9716 | 1 | 2 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 64.6366 | 2 | 2 |
| acid sphingomyelinase | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 14.7695 | 1 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 31.5398 | 1 | 6 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 20.4839 | 1 | 2 |
| AR protein | Homo sapiens (human) | Potency | 24.1523 | 11 | 42 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 25.7090 | 3 | 12 |
| arylsulfatase A | Homo sapiens (human) | Potency | 13.3837 | 1 | 3 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 16.3958 | 2 | 4 |
| Ataxin-2 | Homo sapiens (human) | Potency | 12.9012 | 2 | 3 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 23.3910 | 1 | 3 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 11.8237 | 2 | 3 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 4.7755 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 12.2478 | 2 | 3 |
| BRCA1 | Homo sapiens (human) | Potency | 8.9125 | 1 | 1 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 22.1052 | 1 | 3 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 21.7341 | 1 | 1 |
| caspase-3 | Homo sapiens (human) | Potency | 21.7341 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 48.0499 | 1 | 3 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 6.7341 | 2 | 4 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 29.0941 | 1 | 3 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 44.6684 | 1 | 1 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 9.7199 | 2 | 3 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 28.1838 | 1 | 1 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 23.8362 | 2 | 3 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 32.5297 | 1 | 3 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 1.9953 | 1 | 1 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 23.8362 | 2 | 3 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 62.7171 | 2 | 6 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 8.1548 | 1 | 2 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 7.9251 | 1 | 2 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 10.1030 | 1 | 2 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 37.9083 | 1 | 1 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 12.9244 | 1 | 2 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 18.9930 | 2 | 13 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 11.9877 | 1 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 17.3739 | 1 | 4 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 98.2405 | 1 | 4 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 25.8640 | 1 | 2 |
| endonuclease IV | Escherichia coli | Potency | 10.0000 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 28.5550 | 12 | 45 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 24.6966 | 3 | 10 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 27.4587 | 6 | 28 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 7.5841 | 1 | 11 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 23.9448 | 4 | 17 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 41.0269 | 3 | 6 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 33.1734 | 1 | 1 |
| G | Vesicular stomatitis virus | Potency | 10.1030 | 1 | 2 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 18.5356 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 18.5356 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 18.5356 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 18.5356 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 18.5356 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 18.5356 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 18.5356 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 18.5356 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 18.5356 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 18.5356 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 18.5356 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 18.5356 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 18.5356 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 18.5356 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 18.5356 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 18.5356 | 1 | 7 |
| geminin | Homo sapiens (human) | Potency | 8.3730 | 2 | 4 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 17.9919 | 3 | 16 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| GLS protein | Homo sapiens (human) | Potency | 23.4083 | 2 | 5 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 19.3072 | 1 | 3 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 27.9573 | 4 | 8 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 35.1278 | 1 | 5 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 18.1696 | 2 | 2 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 43.5815 | 2 | 3 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 9.8071 | 2 | 10 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 21.0864 | 1 | 4 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 13.7769 | 2 | 8 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 67.5081 | 2 | 6 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 10.1030 | 1 | 2 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 60.4844 | 2 | 2 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 1.6489 | 2 | 6 |
| IDH1 | Homo sapiens (human) | Potency | 24.8445 | 1 | 2 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 10.1030 | 1 | 4 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 16.9288 | 2 | 3 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 5.9622 | 1 | 2 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 5.9622 | 1 | 2 |
| Interferon beta | Homo sapiens (human) | Potency | 10.1030 | 1 | 2 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 3.7722 | 1 | 4 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 2.0163 | 1 | 4 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 39.0272 | 2 | 7 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 20.1400 | 2 | 3 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 26.5418 | 1 | 3 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 0.0261 | 1 | 3 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 2.5119 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 26.6478 | 4 | 13 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 14.7856 | 1 | 3 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 61.5392 | 1 | 2 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 46.0910 | 1 | 3 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 10.7362 | 1 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 31.1734 | 3 | 17 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 31.5260 | 2 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 0.0078 | 1 | 2 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 84.9214 | 1 | 2 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 32.8699 | 5 | 13 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 31.3436 | 4 | 5 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 63.3425 | 1 | 3 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 10.0000 | 1 | 1 |
| polyprotein | Zika virus | Potency | 33.1734 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 12.6301 | 1 | 2 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 12.5605 | 1 | 2 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 33.6885 | 2 | 11 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 7.0795 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 26.7236 | 2 | 7 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 16.1294 | 2 | 16 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 2.5119 | 1 | 1 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 0.1901 | 1 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 21.9748 | 3 | 21 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 24.0581 | 3 | 17 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 28.4854 | 2 | 4 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 28.4854 | 2 | 4 |
| Smad3 | Homo sapiens (human) | Potency | 4.9288 | 1 | 2 |
| snurportin-1 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 25.1189 | 1 | 1 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 7.7690 | 1 | 2 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 27.9553 | 1 | 5 |
| TDP1 protein | Homo sapiens (human) | Potency | 22.4627 | 2 | 11 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 39.8107 | 1 | 1 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 24.9658 | 2 | 4 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 45.3948 | 3 | 16 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 0.0014 | 1 | 1 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 25.4213 | 5 | 8 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 7.0795 | 1 | 1 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 10.0000 | 1 | 1 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 10.0000 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 29.0904 | 2 | 4 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 43.2754 | 2 | 4 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 18.7511 | 1 | 2 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 70.7946 | 1 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 35.1278 | 1 | 5 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 17-beta-hydroxysteroid dehydrogenase type 1 | Homo sapiens (human) | IC50 | 1.0500 | 1 | 1 |
| 17-beta-hydroxysteroid dehydrogenase type 2 | Homo sapiens (human) | IC50 | 0.3600 | 2 | 2 |
| 3-oxoacyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 4.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | IC50 | 3.9811 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | IC50 | 0.0827 | 3 | 4 |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | Ki | 86.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | Ki | 0.1390 | 1 | 1 |
| 5-hydroxytryptamine receptor 1B | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | IC50 | 0.2430 | 1 | 1 |
| 5-hydroxytryptamine receptor 1B | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | Ki | 0.0945 | 2 | 2 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | IC50 | 3.2389 | 2 | 2 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | Ki | 0.4190 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | IC50 | 2.6769 | 2 | 2 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 0.2180 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 3.6529 | 2 | 2 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 1.2020 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 2.2940 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 1.2020 | 1 | 1 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | IC50 | 4.0384 | 2 | 2 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | Ki | 1.4230 | 1 | 1 |
| 5-hydroxytryptamine receptor 7 | Cavia porcellus (domestic guinea pig) | IC50 | 63.2000 | 1 | 2 |
| 5-hydroxytryptamine receptor 7 | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 7.2500 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | Ki | 92.8000 | 1 | 1 |
| Adenosine receptor A1 | Bos taurus (cattle) | IC50 | 1,006,650,005.0433 | 3 | 3 |
| Adenosine receptor A1 | Homo sapiens (human) | IC50 | 17.1040 | 1 | 1 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | IC50 | 66.2500 | 3 | 4 |
| Adenosine receptor A1 | Bos taurus (cattle) | Ki | 4.1143 | 7 | 7 |
| Adenosine receptor A1 | Cavia porcellus (domestic guinea pig) | Ki | 57.0909 | 7 | 11 |
| Adenosine receptor A1 | Gallus gallus (chicken) | Ki | 6.0000 | 1 | 1 |
| Adenosine receptor A1 | Homo sapiens (human) | Ki | 19.7278 | 28 | 33 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | Ki | 23.7858 | 42 | 71 |
| Adenosine receptor A2a | Homo sapiens (human) | IC50 | 12.4970 | 2 | 3 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | IC50 | 63.0000 | 1 | 5 |
| Adenosine receptor A2a | Cavia porcellus (domestic guinea pig) | Ki | 35.6000 | 3 | 5 |
| Adenosine receptor A2a | Homo sapiens (human) | Ki | 13.7803 | 38 | 48 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | Ki | 94.8753 | 32 | 64 |
| Adenosine receptor A2b | Rattus norvegicus (Norway rat) | IC50 | 63.0000 | 1 | 5 |
| Adenosine receptor A2b | Homo sapiens (human) | Ki | 18.4318 | 29 | 38 |
| Adenosine receptor A2b | Mus musculus (house mouse) | Ki | 23.0000 | 1 | 1 |
| Adenosine receptor A2b | Rattus norvegicus (Norway rat) | Ki | 38.8394 | 20 | 47 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 47.4067 | 28 | 32 |
| Adenosine receptor A3 | Rattus norvegicus (Norway rat) | Ki | 49.9100 | 9 | 15 |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 220.4433 | 3 | 3 |
| Alkaline phosphatase, tissue-nonspecific isozyme | Homo sapiens (human) | IC50 | 52.5000 | 2 | 2 |
| Alkaline phosphatase, tissue-nonspecific isozyme | Homo sapiens (human) | Ki | 82.0000 | 1 | 1 |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.0720 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | IC50 | 54.4900 | 2 | 2 |
| Amine oxidase [flavin-containing] A | Mus musculus (house mouse) | Ki | 19.0000 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | IC50 | 17.1777 | 3 | 3 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | Ki | 3,700.0000 | 2 | 2 |
| Amine oxidase [flavin-containing] B | Mus musculus (house mouse) | Ki | 3.1900 | 1 | 1 |
| Amyloid-beta precursor protein | Homo sapiens (human) | IC50 | 75.1000 | 3 | 3 |
| Androgen receptor | Homo sapiens (human) | IC50 | 9.7000 | 1 | 1 |
| Androgen receptor | Rattus norvegicus (Norway rat) | IC50 | 40.7380 | 1 | 1 |
| Arachidonate 5-lipoxygenase-activating protein | Homo sapiens (human) | IC50 | 44.0000 | 1 | 1 |
| Arginase | Leishmania amazonensis | IC50 | 55.0000 | 1 | 1 |
| Aryl hydrocarbon receptor | Homo sapiens (human) | IC50 | 0.0280 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 4 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 220.8667 | 3 | 3 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | Ki | 48.0000 | 1 | 1 |
| Aurora kinase B | Homo sapiens (human) | IC50 | 4.0300 | 1 | 1 |
| B1 bradykinin receptor | Homo sapiens (human) | Ki | 0.0100 | 1 | 1 |
| B2 bradykinin receptor | Homo sapiens (human) | IC50 | 0.0018 | 1 | 1 |
| B2 bradykinin receptor | Homo sapiens (human) | Ki | 0.0005 | 5 | 5 |
| B2 bradykinin receptor | Rattus norvegicus (Norway rat) | Ki | 0.0005 | 1 | 1 |
| Beta-1 adrenergic receptor | Homo sapiens (human) | IC50 | 0.0575 | 5 | 5 |
| Beta-1 adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0120 | 2 | 3 |
| Beta-1 adrenergic receptor | Homo sapiens (human) | Ki | 0.0042 | 4 | 4 |
| Beta-1 adrenergic receptor | Mus musculus (house mouse) | Ki | 0.0024 | 1 | 1 |
| Beta-1 adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.2713 | 7 | 7 |
| Beta-1 adrenergic receptor | Cavia porcellus (domestic guinea pig) | IC50 | 0.0347 | 1 | 1 |
| Beta-2 adrenergic receptor | Canis lupus familiaris (dog) | IC50 | 0.0170 | 1 | 1 |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | IC50 | 0.0288 | 1 | 1 |
| Beta-2 adrenergic receptor | Homo sapiens (human) | IC50 | 0.0114 | 6 | 6 |
| Beta-2 adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0120 | 2 | 3 |
| Beta-2 adrenergic receptor | Homo sapiens (human) | Ki | 0.0014 | 5 | 5 |
| Beta-2 adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.6000 | 1 | 1 |
| Beta-3 adrenergic receptor | Homo sapiens (human) | IC50 | 0.0493 | 3 | 3 |
| Beta-3 adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0120 | 2 | 3 |
| Beta-3 adrenergic receptor | Homo sapiens (human) | Ki | 0.0990 | 1 | 1 |
| Beta-3 adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.6000 | 1 | 1 |
| Beta-glucuronidase | Homo sapiens (human) | IC50 | 36.4700 | 1 | 1 |
| Bile acid receptor | Homo sapiens (human) | IC50 | 98.4000 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 505.1429 | 4 | 14 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 2 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 4,670.3000 | 3 | 3 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A | Homo sapiens (human) | IC50 | 320.0000 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A | Bos taurus (cattle) | IC50 | 340.4000 | 5 | 5 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Bos taurus (cattle) | IC50 | 300.5000 | 4 | 4 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Homo sapiens (human) | IC50 | 320.0000 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Rattus norvegicus (Norway rat) | IC50 | 70.0000 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C | Homo sapiens (human) | IC50 | 320.0000 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C | Rattus norvegicus (Norway rat) | IC50 | 70.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Homo sapiens (human) | IC50 | 608.8000 | 4 | 5 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Homo sapiens (human) | Ki | 530.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Rattus norvegicus (Norway rat) | Ki | 530.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | IC50 | 527.7500 | 4 | 4 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | Ki | 530.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Rattus norvegicus (Norway rat) | Ki | 530.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4C | Homo sapiens (human) | IC50 | 637.0000 | 3 | 3 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4C | Homo sapiens (human) | Ki | 530.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4C | Rattus norvegicus (Norway rat) | Ki | 530.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Homo sapiens (human) | IC50 | 637.0000 | 3 | 3 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Homo sapiens (human) | Ki | 530.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Rattus norvegicus (Norway rat) | Ki | 530.0000 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 4 |
| Cannabinoid receptor 1 | Homo sapiens (human) | Ki | 0.1834 | 22 | 23 |
| Cannabinoid receptor 1 | Mus musculus (house mouse) | Ki | 1.8470 | 3 | 3 |
| Cannabinoid receptor 1 | Rattus norvegicus (Norway rat) | Ki | 0.6393 | 11 | 12 |
| Cannabinoid receptor 2 | Mus musculus (house mouse) | Ki | 0.5260 | 2 | 2 |
| Cannabinoid receptor 2 | Rattus norvegicus (Norway rat) | Ki | 0.5393 | 3 | 3 |
| Cannabinoid receptor 2 | Homo sapiens (human) | Ki | 0.2699 | 10 | 11 |
| Carbonic anhydrase 1 | Homo sapiens (human) | IC50 | 29,750.0000 | 1 | 4 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 122.2188 | 5 | 16 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 137.1247 | 3 | 14 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | Ki | 149.6769 | 2 | 13 |
| Carbonic anhydrase 14 | Homo sapiens (human) | Ki | 148.1615 | 2 | 13 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | Ki | 9.2300 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | IC50 | 29,750.0000 | 1 | 4 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 121.4766 | 5 | 16 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ki | 147.8923 | 2 | 13 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 138.3500 | 3 | 14 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 209.0385 | 2 | 13 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 170.1154 | 2 | 13 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 197.9615 | 2 | 13 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 137.4732 | 3 | 14 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 146.9214 | 3 | 14 |
| carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1 | Homo sapiens (human) | IC50 | 9.9330 | 1 | 1 |
| Casein kinase II subunit alpha | Homo sapiens (human) | IC50 | 0.7000 | 2 | 2 |
| Casein kinase II subunit alpha 3 | Homo sapiens (human) | IC50 | 0.4000 | 1 | 1 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | IC50 | 0.7000 | 2 | 2 |
| Casein kinase II subunit beta | Homo sapiens (human) | IC50 | 0.7000 | 2 | 2 |
| Cationic trypsin | Bos taurus (cattle) | IC50 | 105.9000 | 1 | 1 |
| CDGSH iron-sulfur domain-containing protein 1 | Homo sapiens (human) | IC50 | 3.1000 | 1 | 1 |
| CDGSH iron-sulfur domain-containing protein 1 | Homo sapiens (human) | Ki | 0.1320 | 1 | 1 |
| cGMP-dependent 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | IC50 | 210.0000 | 1 | 1 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase A | Homo sapiens (human) | IC50 | 300.0000 | 2 | 2 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase B | Homo sapiens (human) | IC50 | 300.0000 | 2 | 2 |
| Chain A, Chitinase | Clonostachys rosea | Ki | 19,700.0000 | 1 | 1 |
| Chain A, Glycogen Phosphorylase | Oryctolagus cuniculus (rabbit) | Ki | 100.0000 | 1 | 1 |
| Chain A, Inosine-5'-monophosphate Dehydrogenase | Tritrichomonas suis | Ki | 0.0650 | 1 | 4 |
| Chain A, Pyridoxal Kinase | Homo sapiens (human) | Ki | 50.0000 | 1 | 2 |
| Chain A, retinol dehydratase | Spodoptera frugiperda (fall armyworm) | Ki | 0.1100 | 1 | 1 |
| Chitotriosidase-1 | Homo sapiens (human) | IC50 | 681.5000 | 1 | 4 |
| Cholecystokinin receptor type A | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Cholinesterase | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Coagulation factor VII | Homo sapiens (human) | IC50 | 120.0000 | 1 | 1 |
| Corticosteroid-binding globulin | Homo sapiens (human) | Ki | 2.4547 | 1 | 1 |
| Corticotropin-releasing factor receptor 2 | Homo sapiens (human) | Ki | 0.1680 | 1 | 1 |
| Cyclin homolog | Herpesvirus saimiri (strain 11) | IC50 | 29.3750 | 1 | 4 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | IC50 | 41.0000 | 1 | 1 |
| Cyclin-dependent kinase 1 | Oryzias latipes (Japanese medaka) | IC50 | 29.3750 | 1 | 4 |
| Cyclin-dependent kinase 5 activator 1 | Homo sapiens (human) | IC50 | 33.7000 | 2 | 5 |
| Cyclin-dependent kinase 6 | Homo sapiens (human) | IC50 | 27.9000 | 2 | 5 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | IC50 | 33.7000 | 2 | 5 |
| Cytochrome P450 1A1 | Homo sapiens (human) | IC50 | 0.6320 | 1 | 1 |
| Cytochrome P450 1A1 | Homo sapiens (human) | Ki | 0.7500 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 2,478.6790 | 4 | 4 |
| Cytochrome P450 1B1 | Homo sapiens (human) | IC50 | 0.0470 | 1 | 1 |
| Cytochrome P450 1B1 | Homo sapiens (human) | Ki | 0.0430 | 1 | 1 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Cytochrome P450 2C8 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 36.6667 | 2 | 3 |
| Cytochrome P450 2C9 | Homo sapiens (human) | Ki | 6.0000 | 1 | 1 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 4.7280 | 4 | 4 |
| Cytochrome P450 2J2 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 2 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 10.0000 | 3 | 3 |
| D(1A) dopamine receptor | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| D(2) dopamine receptor | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | Ki | 2.5003 | 2 | 2 |
| Death-associated protein kinase 1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Delta-type opioid receptor | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Dihydrofolate reductase | Homo sapiens (human) | Ki | 17,000.0000 | 1 | 1 |
| Dihydroorotate dehydrogenase | Leishmania major | IC50 | 393.5035 | 1 | 2 |
| Dihydroorotate dehydrogenase (quinone), mitochondrial | Homo sapiens (human) | IC50 | 0.8800 | 1 | 1 |
| Dihydroorotate dehydrogenase (quinone), mitochondrial | Homo sapiens (human) | Ki | 0.7100 | 1 | 1 |
| Dipeptidyl peptidase 3 | Homo sapiens (human) | IC50 | 32.9000 | 1 | 1 |
| Dipeptidyl peptidase 4 | Homo sapiens (human) | IC50 | 66.2450 | 2 | 2 |
| DNA-dependent protein kinase catalytic subunit | Homo sapiens (human) | IC50 | 10,000.0000 | 1 | 1 |
| E3 ubiquitin-protein ligase XIAP | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Endochitinase B1 | Aspergillus fumigatus | IC50 | 681.5000 | 1 | 4 |
| Endothelin-1 receptor | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Enoyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 20.0000 | 1 | 1 |
| Fatty acid-binding protein 5 | Homo sapiens (human) | Ki | 1.5933 | 1 | 3 |
| Fatty acid-binding protein, liver | Mus musculus (house mouse) | Ki | 0.1110 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | Homo sapiens (human) | IC50 | 3.7500 | 2 | 2 |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | IC50 | 11.7490 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | Ki | 0.1800 | 1 | 1 |
| G2/mitotic-specific cyclin-B | Marthasterias glacialis (spiny starfish) | IC50 | 29.3750 | 1 | 4 |
| G2/mitotic-specific cyclin-B1 | Homo sapiens (human) | IC50 | 41.0000 | 1 | 1 |
| G2/mitotic-specific cyclin-B2 | Homo sapiens (human) | IC50 | 41.0000 | 1 | 1 |
| G2/mitotic-specific cyclin-B3 | Homo sapiens (human) | IC50 | 41.0000 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | IC50 | 0.4749 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 0.4749 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 0.4749 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 0.4749 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 0.4749 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | IC50 | 0.4749 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | IC50 | 0.4749 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | IC50 | 0.4749 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 0.4749 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | IC50 | 0.4749 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | IC50 | 0.4749 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | IC50 | 0.4749 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | IC50 | 0.4749 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | IC50 | 0.4749 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | IC50 | 0.4749 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | IC50 | 0.4749 | 2 | 3 |
| Genome polyprotein | | IC50 | 180.0000 | 1 | 1 |
| Glucose-6-phosphate 1-dehydrogenase | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Glutamate receptor 1 | Homo sapiens (human) | Ki | 110.0000 | 1 | 1 |
| Glutamate receptor 2 | Homo sapiens (human) | Ki | 110.0000 | 1 | 1 |
| Glutamate receptor 3 | Homo sapiens (human) | Ki | 110.0000 | 1 | 1 |
| Glutamate receptor 4 | Homo sapiens (human) | Ki | 110.0000 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | Ki | 110.0000 | 1 | 1 |
| Glycogen phosphorylase, liver form | Rattus norvegicus (Norway rat) | IC50 | 648.0000 | 1 | 1 |
| Glycogen phosphorylase, muscle form | Oryctolagus cuniculus (rabbit) | IC50 | 159.1933 | 13 | 15 |
| Glycogen phosphorylase, muscle form | Rattus norvegicus (Norway rat) | IC50 | 182.0000 | 1 | 1 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | IC50 | 3.5000 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | IC50 | 3.5000 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Rattus norvegicus (Norway rat) | IC50 | 29.3750 | 1 | 4 |
| Guanine deaminase | Homo sapiens (human) | Ki | 10.2000 | 1 | 1 |
| High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Histone-lysine N-methyltransferase SETD7 | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Ileal sodium/bile acid cotransporter | Homo sapiens (human) | Ki | 6.3000 | 1 | 2 |
| Inositol hexakisphosphate kinase 2 | Homo sapiens (human) | IC50 | 2.5000 | 1 | 1 |
| Inositol polyphosphate multikinase | Homo sapiens (human) | IC50 | 4.4000 | 1 | 1 |
| Integrase | Human immunodeficiency virus 1 | IC50 | 81.2500 | 2 | 2 |
| Interstitial collagenase | Homo sapiens (human) | IC50 | 2.6350 | 1 | 2 |
| Intestinal-type alkaline phosphatase | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Kappa-type opioid receptor | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Lactoylglutathione lyase | Homo sapiens (human) | IC50 | 20.6000 | 1 | 1 |
| Lanosterol 14-alpha demethylase | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | IC50 | 18.7500 | 1 | 2 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 18.7500 | 1 | 2 |
| Mu-type opioid receptor | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Multidrug resistance-associated protein 1 | Homo sapiens (human) | Ki | 2.4000 | 2 | 2 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 4 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Myeloperoxidase | Homo sapiens (human) | IC50 | 2.2400 | 1 | 1 |
| Myoglobin | Homo sapiens (human) | IC50 | 2.3000 | 1 | 1 |
| NADPH oxidase 4 | Homo sapiens (human) | IC50 | 1.2000 | 1 | 1 |
| Neuraminidase | Influenza A virus (A/USSR/90/1977(H1N1)) | IC50 | 63.7000 | 2 | 2 |
| Neuraminidase | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 38.5750 | 4 | 4 |
| Neuraminidase | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | Ki | 21.1000 | 1 | 1 |
| Palmitoleoyl-protein carboxylesterase NOTUM | Homo sapiens (human) | IC50 | 18.6000 | 1 | 1 |
| Pancreatic triacylglycerol lipase | Sus scrofa (pig) | IC50 | 85.0000 | 2 | 2 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Homo sapiens (human) | IC50 | 3,267.0000 | 1 | 2 |
| Phosphodiesterase | Bos taurus (cattle) | IC50 | 250.3333 | 6 | 6 |
| Phosphodiesterase | Rattus norvegicus (Norway rat) | IC50 | 70.0000 | 1 | 1 |
| Phosphodiesterase | Bos taurus (cattle) | Ki | 77.0000 | 1 | 1 |
| Phospholipase A-2-activating protein | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Polyphenol oxidase 2 | Agaricus bisporus | IC50 | 135.7000 | 2 | 2 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | IC50 | 28.3500 | 2 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | IC50 | 15.2900 | 2 | 2 |
| Potassium channel subfamily K member 2 | Bos taurus (cattle) | IC50 | 1.0000 | 1 | 1 |
| Potassium channel subfamily K member 3 | Homo sapiens (human) | IC50 | 3.0000 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 2.8280 | 1 | 1 |
| Prolyl endopeptidase | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 150.0000 | 2 | 2 |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | IC50 | 372.0000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | IC50 | 500.0000 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | IC50 | 500.0000 | 1 | 1 |
| Proteasome subunit beta type-5 | Homo sapiens (human) | IC50 | 10.7500 | 2 | 2 |
| Protein E6 | Human papillomavirus 16 | IC50 | 20.0000 | 1 | 1 |
| rac GTPase-activating protein 1 isoform a | Homo sapiens (human) | IC50 | 44.4900 | 1 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | IC50 | 2.3200 | 1 | 1 |
| Renin | Homo sapiens (human) | Ki | 6.5500 | 1 | 3 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 100.0000 | 1 | 2 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 100.0000 | 1 | 2 |
| Serine-protein kinase ATM | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Serine/threonine-protein kinase ATR | Homo sapiens (human) | IC50 | 1,100.0000 | 1 | 1 |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | IC50 | 400.0000 | 1 | 1 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | IC50 | 1.3000 | 1 | 1 |
| Short transient receptor potential channel 5 | Homo sapiens (human) | IC50 | 3.9000 | 1 | 1 |
| Sialidase | Clostridium perfringens | IC50 | 8.0000 | 1 | 1 |
| Sialidase-2 | Homo sapiens (human) | IC50 | 230.0000 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | IC50 | 2.8700 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | Ki | 7.9000 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | Ki | 1.2060 | 1 | 1 |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | IC50 | 2.1000 | 1 | 1 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | IC50 | 0.3800 | 1 | 1 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | Ki | 0.2020 | 1 | 1 |
| Sodium/bile acid cotransporter | Homo sapiens (human) | IC50 | 5.5000 | 1 | 1 |
| Solute carrier family 15 member 1 | Homo sapiens (human) | Ki | 110.0000 | 2 | 2 |
| Solute carrier family 15 member 2 | Homo sapiens (human) | Ki | 37.0768 | 1 | 2 |
| Solute carrier family 2, facilitated glucose transporter member 1 | Homo sapiens (human) | IC50 | 4.0000 | 1 | 1 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | IC50 | 63.2000 | 1 | 1 |
| Solute carrier family 22 member 20 | Mus musculus (house mouse) | Ki | 310.5150 | 1 | 2 |
| Solute carrier family 22 member 6 | Homo sapiens (human) | IC50 | 22.5000 | 2 | 2 |
| Solute carrier family 22 member 6 | Homo sapiens (human) | Ki | 82.0000 | 1 | 2 |
| Solute carrier family 22 member 6 | Mus musculus (house mouse) | Ki | 55.8114 | 2 | 3 |
| Solute carrier family 22 member 6 | Rattus norvegicus (Norway rat) | Ki | 1,063.2500 | 2 | 2 |
| Solute carrier family 22 member 8 | Homo sapiens (human) | Ki | 31.0000 | 1 | 1 |
| Solute carrier family 22 member 8 | Rattus norvegicus (Norway rat) | Ki | 19.0000 | 1 | 1 |
| Solute carrier organic anion transporter family member 1A1 | Rattus norvegicus (Norway rat) | Ki | 10.6000 | 1 | 1 |
| Steroid hormone receptor ERR1 | Homo sapiens (human) | IC50 | 9.6400 | 1 | 1 |
| Substance-K receptor | Cavia porcellus (domestic guinea pig) | IC50 | 58.6000 | 1 | 1 |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | IC50 | 58.6000 | 1 | 1 |
| Thyroid hormone receptor beta | Rattus norvegicus (Norway rat) | Ki | 14.0000 | 1 | 1 |
| Tissue factor | Homo sapiens (human) | IC50 | 120.0000 | 1 | 1 |
| Transient receptor potential cation channel subfamily V member 2 | Rattus norvegicus (Norway rat) | IC50 | 4.7800 | 2 | 2 |
| Trypsin | Sus scrofa (pig) | IC50 | 200.0000 | 1 | 1 |
| Type-1 angiotensin II receptor | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Tyrosinase | Homo sapiens (human) | IC50 | 33.0550 | 2 | 2 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | Ki | 6.7700 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | IC50 | 6.4000 | 1 | 1 |
| Vasopressin V1a receptor | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Vitamin D3 receptor | Homo sapiens (human) | IC50 | 100.0000 | 2 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Cavia porcellus (domestic guinea pig) | IC50 | 21.0000 | 1 | 4 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | IC50 | 21.0000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Rattus norvegicus (Norway rat) | IC50 | 21.0000 | 1 | 1 |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | IC50 | 1.0600 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | Kd | 0.0031 | 2 | 3 |
| 5-hydroxytryptamine receptor 1B | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| 5-hydroxytryptamine receptor 7 | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Adenosine receptor A1 | Homo sapiens (human) | Kd | 28.5000 | 1 | 2 |
| Adenosine receptor A2a | Homo sapiens (human) | EC50 | 16.6059 | 2 | 2 |
| Adenosine receptor A2a | Homo sapiens (human) | Kd | 7.8127 | 3 | 5 |
| Adenosine receptor A3 | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Albumin | Homo sapiens (human) | Kd | 520.3425 | 6 | 6 |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | Kd | 100.0000 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Kd | 0.0148 | 1 | 1 |
| Alpha-1B adrenergic receptor | Homo sapiens (human) | Kd | 100.0000 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Kd | 0.0148 | 1 | 1 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | Kd | 100.0000 | 1 | 1 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | Kd | 0.0148 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Kd | 100.0000 | 1 | 1 |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | Kd | 0.0148 | 1 | 1 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Kd | 100.0000 | 1 | 1 |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | Kd | 0.0148 | 1 | 1 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | Kd | 100.0000 | 1 | 1 |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | Kd | 0.0148 | 1 | 1 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | Kd | 6.7608 | 1 | 1 |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | Kd | 6.7000 | 1 | 1 |
| B2 bradykinin receptor | Homo sapiens (human) | EC50 | 0.0000 | 1 | 1 |
| Beta-1 adrenergic receptor | Homo sapiens (human) | Kd | 0.0314 | 7 | 11 |
| Beta-1 adrenergic receptor | Rattus norvegicus (Norway rat) | Kd | 0.0044 | 2 | 2 |
| Beta-1 adrenergic receptor | Cavia porcellus (domestic guinea pig) | Kd | 0.0359 | 11 | 11 |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | Kd | 0.0045 | 5 | 7 |
| Beta-2 adrenergic receptor | Homo sapiens (human) | Kd | 0.0223 | 9 | 13 |
| Beta-3 adrenergic receptor | Homo sapiens (human) | Kd | 0.0514 | 6 | 10 |
| Bile acid receptor | Homo sapiens (human) | EC50 | 47.5000 | 2 | 2 |
| Cannabinoid receptor 1 | Rattus norvegicus (Norway rat) | EC50 | 11.9039 | 3 | 4 |
| Chain A, Glycogen phosphorylase, liver form | Homo sapiens (human) | Kd | 100.0000 | 1 | 8 |
| Chain A, NDP kinase | Dictyostelium discoideum | Kd | 24.0000 | 1 | 1 |
| Chain A, STEROID DELTA-ISOMERASE | Pseudomonas putida | Kd | 45.7400 | 1 | 1 |
| Chain A, Transthyretin | Homo sapiens (human) | Kd | 2.1000 | 1 | 5 |
| Chain B, Transthyretin | Homo sapiens (human) | Kd | 2.1000 | 1 | 2 |
| Cholecystokinin receptor type A | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Cytochrome P450 1A1 | Homo sapiens (human) | Kd | 19.1000 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| D(2) dopamine receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | Kd | 150.4000 | 4 | 5 |
| Delta-type opioid receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Endothelin-1 receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Fatty acid-binding protein 5 | Mus musculus (house mouse) | Kd | 0.1003 | 1 | 1 |
| G-protein coupled bile acid receptor 1 | Homo sapiens (human) | EC50 | 10.9975 | 1 | 4 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | EC50 | 29.1000 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Homo sapiens (human) | EC50 | 29.1000 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Homo sapiens (human) | EC50 | 29.1000 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | EC50 | 15.8489 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | EC50 | 15.8489 | 1 | 1 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | EC50 | 15.8489 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | EC50 | 15.8489 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | EC50 | 0.2825 | 4 | 4 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | EC50 | 0.6500 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | EC50 | 0.2000 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | EC50 | 0.6500 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | EC50 | 0.5300 | 1 | 1 |
| glycogen synthase kinase-3 beta isoform 1 | Homo sapiens (human) | EC50 | 11.5900 | 1 | 1 |
| Kappa-type opioid receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Mu-type opioid receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Neuromedin-K receptor | Cavia porcellus (domestic guinea pig) | Kd | 0.0024 | 1 | 1 |
| Nuclear receptor subfamily 2 group E member 1 | Homo sapiens (human) | EC50 | 33.6667 | 3 | 3 |
| Nuclear receptor subfamily 2 group E member 1 | Homo sapiens (human) | Kd | 0.5000 | 1 | 1 |
| Olfactory receptor 51E2 | Homo sapiens (human) | EC50 | 0.0013 | 1 | 1 |
| Oxysterols receptor LXR-alpha | Homo sapiens (human) | EC50 | 0.1300 | 2 | 2 |
| Palmitoleoyl-protein carboxylesterase NOTUM | Homo sapiens (human) | EC50 | 45.8000 | 1 | 1 |
| Palmitoleoyl-protein carboxylesterase NOTUM | Homo sapiens (human) | Kd | 3,442.5000 | 1 | 2 |
| Potassium channel subfamily K member 2 | Homo sapiens (human) | EC50 | 431.5000 | 1 | 2 |
| Prostacyclin receptor | Homo sapiens (human) | EC50 | 0.0019 | 1 | 1 |
| Prostaglandin D2 receptor | Homo sapiens (human) | EC50 | 0.0006 | 1 | 1 |
| Prostaglandin E2 receptor EP1 subtype | Homo sapiens (human) | EC50 | 0.2850 | 1 | 1 |
| Prostaglandin E2 receptor EP2 subtype | Homo sapiens (human) | EC50 | 0.0062 | 1 | 1 |
| Sex hormone-binding globulin | Homo sapiens (human) | Kd | 0.0708 | 1 | 1 |
| Steroid Delta-isomerase | Pseudomonas putida | Kd | 16.0000 | 2 | 2 |
| Trace amine-associated receptor 1 | Homo sapiens (human) | EC50 | 0.3080 | 1 | 1 |
| Transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | EC50 | 0.7830 | 6 | 6 |
| Type-1 angiotensin II receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Vasopressin V1a receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Vitamin D3 receptor | Homo sapiens (human) | EC50 | 150.0000 | 2 | 2 |