11 beta-hydroxyandrosterone

Description

11 beta-hydroxyandrosterone: RN given refers to (3alpha,5alpha,11beta)-isomer; structure [MeSH]

3alpha,11beta-Dihydroxy-5alpha-androstane-17-one : no description available [CHeBI]

Cross-References

ID Source	ID
PubMed CID	10286365
CHEMBL ID	1908033
SCHEMBL ID	3362889
CHEBI ID	34350
MeSH ID	M0043165

Synonyms (42)

Synonym
57-61-4
nsc-56288
3alpha,11beta-dihydroxy-5alpha-androstane-17-one
11beta-hydroxyandrosterone
11-hydroxyetiocholanolone
LMST02020086
11-hydroxyandrosterone
3,11-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-one
(3r,5s,8s,9s,10s,11s,13s,14s)-3,11-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-one
nsc 56288
androstan-17-one, 3,11-dihydroxy-, (3alpha,5alpha,11beta)-
0jyd539gc3 ,
unii-0jyd539gc3
chebi:34350 ,
CHEMBL1908033
11-oxyetiocholanolone
5.alpha.-androstan-17-one, 3.alpha.,11.beta.-dihydroxy-
ba-2685
11.beta.-hydroxyandrosterone
androstan-17-one, 3,11-dihydroxy-, (3.alpha.,5.alpha.,11.beta.)-
3.alpha.,11.beta.-dihydroxy-5.alpha.-androstane-17-one
3.alpha.,11.beta.-dihydroxy-5.alpha.-androstan-17-one
11.beta.-oh-androsterone
5.alpha.-androstane-3.alpha.,11.beta.-diol-17-one
SCHEMBL3362889
11-beta-hydroxyandrosterone
3,11-dihydroxyandrostan-17-one #
5.alpha.-androstan-3.alpha.,11.beta.-diol-17-one
PIXFHVWJOVNKQK-PTXZMSDUSA-N
11-.beta.-hydroxyandrosterone
11-\|a inverted exclamation mark-hydroxyandrosterone
11beta-hydroxy-androsterone
11-hydroxy-androsterone
3alpha,11beta-dihydroxy-5alpha-androstan-17-one
5alpha-androstan-3alpha,11beta-diol-17-one
Q27116006
DTXSID301018932
11 beta-hydroxyandrosterone
MS-24441
11\|a-hydroxyandrosterone
CS-0062274
HY-113351

Roles (1)

Role	Description
androgen	A sex hormone that stimulates or controls the development and maintenance of masculine characteristics in vertebrates by binding to androgen receptors.

Drug Classes (1)

Class	Description
3-hydroxy steroid	Any hydroxy steroid carrying a hydroxy group at position 3.

Pathways (1)

11 beta-hydroxyandrosterone is involved in 1 pathway(s), involving a total of 14 unique proteins and 11 unique compounds

Pathway	Proteins	Compounds
Glucocorticoid biosynthesis	14	11

Bioassays (3)

Assay ID	Title	Year	Journal	Article
AID624618	Specific activity of expressed human recombinant UGT2B4	2000	Annual review of pharmacology and toxicology, , Volume: 40ISSN: 0362-1642	Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
AID624616	Specific activity of expressed human recombinant UGT2B15	2000	Annual review of pharmacology and toxicology, , Volume: 40ISSN: 0362-1642	Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
AID624619	Specific activity of expressed human recombinant UGT2B7	2000	Annual review of pharmacology and toxicology, , Volume: 40ISSN: 0362-1642	Human UDP-glucuronosyltransferases: metabolism, expression, and disease.

Research

Studies (26)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	13 (50.00)	18.7374
1990's	2 (7.69)	18.2507
2000's	4 (15.38)	29.6817
2010's	7 (26.92)	24.3611
2020's	0 (0.00)	2.80

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	2 (7.69%)	6.00%
Case Studies	2 (7.69%)	4.05%
Observational	0 (0.00%)	0.25%
Other	22 (84.62%)	84.16%

Substance	Classes	Roles	Relationship Strength
testosterone	3-hydroxy steroid	androgen	low
estriol	16alpha-hydroxy steroid; 17beta-hydroxy steroid; 3-hydroxy steroid	estrogen; human metabolite; human xenobiotic metabolite; mouse metabolite	low
estrone	17-oxo steroid; 3-hydroxy steroid; phenolic steroid; phenols	antineoplastic agent; bone density conservation agent; estrogen; human metabolite; mouse metabolite	low
17-desoxyestradiol	3-hydroxy steroid; phenolic steroid; phenols	estrogen	low
ethinyl estradiol	17-hydroxy steroid; 3-hydroxy steroid; terminal acetylenic compound	xenoestrogen	low
dimethisterone	3-hydroxy steroid	androgen	low
estetrol	15alpha-hydroxy steroid; 16alpha-hydroxy steroid; 17beta-hydroxy steroid; 3-hydroxy steroid; steroid hormone	estrogen receptor agonist; estrogen; human metabolite; human xenobiotic metabolite; oral contraceptive	low
calusterone	3-hydroxy steroid	androgen	low
androstane-3,17-diol	17-hydroxy steroid; 3-hydroxy steroid; androstanoid		low
17-methylestradiol	3-hydroxy steroid		low
2-methoxyestradiol	17beta-hydroxy steroid; 3-hydroxy steroid	angiogenesis modulating agent; antimitotic; antineoplastic agent; human metabolite; metabolite; mouse metabolite	low
estradiol 17-sulfate	3-hydroxy steroid; phenolic steroid; steroid sulfate	human urinary metabolite	low
11-beta-chloromethyl-estradiol	3-hydroxy steroid		low
alfatradiol	17alpha-hydroxy steroid; 3-hydroxy steroid; estradiol	estrogen; geroprotector	low
4-methoxyestradiol	17beta-hydroxy steroid; 3-hydroxy steroid; aromatic ether; phenols	estrogen; human metabolite; rat metabolite	low
clostebol	3-hydroxy steroid	androgen	low
androstan-3-ol	3-hydroxy steroid	androgen	low
d-4-chloro-17 beta-hydroxy-3-oxo-17 alpha-methylandrosta-1,4-diene	3-hydroxy steroid	androgen	low
11-ketoetiocholanolone	3-hydroxy steroid	androgen	low
1,3,5,(10),16-estratetraen-3-ol	3-hydroxy steroid		low
bolasterone	3-hydroxy steroid	androgen	low
fulvestrant	17beta-hydroxy steroid; 3-hydroxy steroid; organofluorine compound; sulfoxide	antineoplastic agent; estrogen antagonist; estrogen receptor antagonist	low
ici 164384	17beta-hydroxy steroid; 3-hydroxy steroid; tertiary carboxamide	anti-estrogen; antineoplastic agent; estrogen receptor antagonist	low
11-hydroxyandrostenedione	3-hydroxy steroid	androgen	low
estriol-16 alpha-glucuronide	17beta-hydroxy steroid; 3-hydroxy steroid; beta-D-glucosiduronic acid; phenols; steroid glucosiduronic acid	human urinary metabolite	low
4-androstene-3,17-diol	3-hydroxy steroid	androgen	low
equilin	17-oxo steroid; 3-hydroxy steroid		low
methandriol	3-hydroxy steroid	androgen	low
stenbolone	3-hydroxy steroid	androgen	low
stigmastanol	3-hydroxy steroid; phytosterols	anticholesteremic drug; plant metabolite	low
16-ketoestrone	3-hydroxy steroid		low
2-methoxyestrone	17-oxo steroid; 3-hydroxy steroid; alicyclic ketone; aromatic ether; phenolic steroid; phenols	human metabolite; mouse metabolite	low
equilenin	17-oxo steroid; 3-hydroxy steroid	antioxidant; mammalian metabolite	low
trilostane	17beta-hydroxy steroid; 3-hydroxy steroid; androstanoid; epoxy steroid; nitrile	abortifacient; antineoplastic agent; EC 1.1.1.210 [3beta(or 20alpha)-hydroxysteroid dehydrogenase] inhibitor	low
methenolone	3-hydroxy steroid	androgen	low
estradiol-17 beta-glucuronide	3-hydroxy steroid; steroid glucosiduronic acid		low
pregna-4,17-diene-3,16-dione	3-hydroxy steroid	androgen	low
tetrahydrogestrinone	3-hydroxy steroid		low
tipredane	3-hydroxy steroid	androgen	low
ru 58668	17beta-hydroxy steroid; 3-hydroxy steroid; aromatic ether; organofluorine compound; sulfone	anti-estrogen; antineoplastic agent; estrogen receptor antagonist	low
5-androstene-3,16,17-triol	3-hydroxy steroid	androgen	low
4-hydroxyestrone	17-oxo steroid; 3-hydroxy steroid; 4-hydroxy steroid; catechols; phenolic steroid	carcinogenic agent; estrogen; human urinary metabolite	low
altrenogest	3-hydroxy steroid		low
quinbolone	3-hydroxy steroid	androgen	low
3beta-hydroxy-17-(1h-benzimidazole-1-yl)androsta-5,16-diene	3-hydroxy steroid	androgen	low
moxestrol	3-hydroxy steroid		low

Substance	Classes	Roles	Relationship Strength
testosterone	3-hydroxy steroid	androgen	low
oxandrolone	17beta-hydroxy steroid; 3-oxo steroid; anabolic androgenic steroid; oxa-steroid	anabolic agent; androgen	low
androsterone	17-oxo steroid; 3alpha-hydroxy steroid; androstanoid; C19-steroid	androgen; anticonvulsant; human blood serum metabolite; human metabolite; human urinary metabolite; mouse metabolite; pheromone	low
dehydroepiandrosterone	17-oxo steroid; 3beta-hydroxy-Delta(5)-steroid; androstanoid	androgen; human metabolite; mouse metabolite	low
methyltestosterone	17beta-hydroxy steroid; 3-oxo-Delta(4) steroid; enone	anabolic agent; androgen; antineoplastic agent	low
androstenedione	17-oxo steroid; 3-oxo-Delta(4) steroid; androstanoid	androgen; Daphnia magna metabolite; human metabolite; mouse metabolite	low
medroxyprogesterone acetate	20-oxo steroid; 3-oxo-Delta(4) steroid; acetate ester; corticosteroid; steroid ester	adjuvant; androgen; antineoplastic agent; antioxidant; female contraceptive drug; inhibitor; progestin; synthetic oral contraceptive	low
dimethisterone	3-hydroxy steroid	androgen	low
testosterone enanthate	heptanoate ester; sterol ester	androgen	low
androstenediol	17beta-hydroxy steroid; 3beta-hydroxy-Delta(5)-steroid	androgen; human metabolite; mouse metabolite; radiation protective agent	low
dihydrotestosterone	17beta-hydroxy steroid; 17beta-hydroxyandrostan-3-one; 3-oxo-5alpha-steroid	androgen; Daphnia magna metabolite; human metabolite; mouse metabolite	low
stanozolol	17beta-hydroxy steroid; anabolic androgenic steroid; organic heteropentacyclic compound; tertiary alcohol	anabolic agent; androgen	low
calusterone	3-hydroxy steroid	androgen	low
16-hydroxytestosterone	16alpha-hydroxy steroid; 17beta-hydroxy steroid; 3-oxo-Delta(4) steroid; androstanoid; C19-steroid; diol; secondary alcohol	androgen	low
clostebol	3-hydroxy steroid	androgen	low
androstan-3-ol	3-hydroxy steroid	androgen	low
d-4-chloro-17 beta-hydroxy-3-oxo-17 alpha-methylandrosta-1,4-diene	3-hydroxy steroid	androgen	low
11-ketoetiocholanolone	3-hydroxy steroid	androgen	low
bolasterone	3-hydroxy steroid	androgen	low
11-hydroxyandrostenedione	3-hydroxy steroid	androgen	low
4-androstene-3,17-diol	3-hydroxy steroid	androgen	low
adrenosterone	11-oxo steroid; 17-oxo steroid; 3-oxo-Delta(4) steroid; androstanoid	androgen; EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor; human urinary metabolite; marine metabolite	low
methandriol	3-hydroxy steroid	androgen	low
nandrolone phenpropionate	3-phenylpropionate ester	anabolic agent; androgen	low
stenbolone	3-hydroxy steroid	androgen	low
15-hydroxytestosterone	15alpha-hydroxy steroid; 17beta-hydroxy steroid; 3-oxo-Delta(4) steroid; androstanoid	androgen; Daphnia magna metabolite	low
epietiocholanolone	17-oxo steroid; 3beta-hydroxy steroid; androstanoid	androgen; animal metabolite; human blood serum metabolite; mouse metabolite; rat metabolite	low
mibolerone	17beta-hydroxy steroid; 3-oxo-Delta(4) steroid	anabolic agent; androgen	low
metribolone	17beta-hydroxy steroid; 3-oxo steroid; anabolic androgenic steroid	androgen	low
epiandrosterone	17-oxo steroid; 3beta-hydroxy steroid; androstanoid	androgen; human metabolite	low
methenolone	3-hydroxy steroid	androgen	low
11-ketotestosterone	11-oxo steroid; 17beta-hydroxy steroid; 3-oxo-Delta(4) steroid; androstanoid	androgen; human metabolite; marine xenobiotic metabolite	low
pregna-4,17-diene-3,16-dione	3-hydroxy steroid	androgen	low
tipredane	3-hydroxy steroid	androgen	low
5-androstene-3,16,17-triol	3-hydroxy steroid	androgen	low
quinbolone	3-hydroxy steroid	androgen	low
3beta-hydroxy-17-(1h-benzimidazole-1-yl)androsta-5,16-diene	3-hydroxy steroid	androgen	low

Substance	Classes	Roles	Relationship Strength
testosterone	3-hydroxy steroid	androgen	low
dimethisterone	3-hydroxy steroid	androgen	low
calusterone	3-hydroxy steroid	androgen	low
clostebol	3-hydroxy steroid	androgen	low
androstan-3-ol	3-hydroxy steroid	androgen	low
d-4-chloro-17 beta-hydroxy-3-oxo-17 alpha-methylandrosta-1,4-diene	3-hydroxy steroid	androgen	low
11-ketoetiocholanolone	3-hydroxy steroid	androgen	low
bolasterone	3-hydroxy steroid	androgen	low
11-hydroxyandrostenedione	3-hydroxy steroid	androgen	low
4-androstene-3,17-diol	3-hydroxy steroid	androgen	low
methandriol	3-hydroxy steroid	androgen	low
stenbolone	3-hydroxy steroid	androgen	low
methenolone	3-hydroxy steroid	androgen	low
pregna-4,17-diene-3,16-dione	3-hydroxy steroid	androgen	low
tipredane	3-hydroxy steroid	androgen	low
5-androstene-3,16,17-triol	3-hydroxy steroid	androgen	low
quinbolone	3-hydroxy steroid	androgen	low
3beta-hydroxy-17-(1h-benzimidazole-1-yl)androsta-5,16-diene	3-hydroxy steroid	androgen	low

Substance	Studies	Classes	Roles	First Year	Last Year	Average Age	Relationship Strength	1990's
4-hydroxybenzoic acid	1	monohydroxybenzoic acid	algal metabolite; plant metabolite	2000	2000	24.0	low	1
benzoic acid	1	benzoic acids	algal metabolite; antimicrobial food preservative; drug allergen; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; EC 3.1.1.3 (triacylglycerol lipase) inhibitor; human xenobiotic metabolite; plant metabolite	2000	2000	24.0	low	1
benzyl alcohol	1	benzyl alcohols	antioxidant; fragrance; metabolite; solvent	2000	2000	24.0	low	1
butyric acid	1	fatty acid 4:0; straight-chain saturated fatty acid	human urinary metabolite; Mycoplasma genitalium metabolite	2000	2000	24.0	low	1
salicylic acid	1	monohydroxybenzoic acid	algal metabolite; antifungal agent; antiinfective agent; EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor; keratolytic drug; plant hormone; plant metabolite	2000	2000	24.0	low	1
gallic acid	1	trihydroxybenzoic acid	antineoplastic agent; antioxidant; apoptosis inducer; astringent; cyclooxygenase 2 inhibitor; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; geroprotector; human xenobiotic metabolite; plant metabolite	2000	2000	24.0	low	1
octanoic acid	1	medium-chain fatty acid; straight-chain saturated fatty acid	antibacterial agent; Escherichia coli metabolite; human metabolite	2000	2000	24.0	low	1
4-aminophenol	1	aminophenol	allergen; metabolite	2000	2000	24.0	low	1
hydroquinone	1	benzenediol; hydroquinones	antioxidant; carcinogenic agent; cofactor; Escherichia coli metabolite; human xenobiotic metabolite; mouse metabolite; skin lightening agent	2000	2000	24.0	low	1
methanol	1	alkyl alcohol; one-carbon compound; primary alcohol; volatile organic compound	amphiprotic solvent; Escherichia coli metabolite; fuel; human metabolite; mouse metabolite; Mycoplasma genitalium metabolite	2000	2000	24.0	low	1
n,n-dimethylaniline	1	dimethylaniline; tertiary amine		2000	2000	24.0	low	1
4-nitrophenol	1	4-nitrophenols	human xenobiotic metabolite; mouse metabolite	2000	2000	24.0	low	1
phenol	1	phenols	antiseptic drug; disinfectant; human xenobiotic metabolite; mouse metabolite	2000	2000	24.0	low	1
pyrogallol	1	benzenetriol; phenolic donor	plant metabolite	2000	2000	24.0	low	1
tryptophan	1	alpha-amino acid; amino acid zwitterion; aminoalkylindole; aromatic amino acid; polar amino acid	Daphnia magna metabolite	2000	2000	24.0	medium	1
vanillin	1	benzaldehydes; monomethoxybenzene; phenols	anti-inflammatory agent; anticonvulsant; antioxidant; flavouring agent; plant metabolite	2000	2000	24.0	low	1
catechin	1	hydroxyflavan		2000	2000	24.0	low	1
menthol	1	p-menthane monoterpenoid; secondary alcohol	volatile oil component	2000	2000	24.0	low	1
2-aminofluorene	1			2000	2000	24.0	low	1
homovanillic acid	1	guaiacols; monocarboxylic acid	human metabolite; mouse metabolite	2000	2000	24.0	low	1
6-hydroxymelatonin	1	acetamides; tryptamines	metabolite; mouse metabolite	2000	2000	24.0	low	1
oxyquinoline	1	monohydroxyquinoline	antibacterial agent; antifungal agrochemical; antiseptic drug; iron chelator	2000	2000	24.0	low	1
acetaminophen	1	acetamides; phenols	antipyretic; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; cyclooxygenase 3 inhibitor; environmental contaminant; ferroptosis inducer; geroprotector; hepatotoxic agent; human blood serum metabolite; non-narcotic analgesic; non-steroidal anti-inflammatory drug; xenobiotic	2000	2000	24.0	low	1
amitriptyline	1	carbotricyclic compound; tertiary amine	adrenergic uptake inhibitor; antidepressant; environmental contaminant; tropomyosin-related kinase B receptor agonist; xenobiotic	2000	2000	24.0	low	1
aspirin	1	benzoic acids; phenyl acetates; salicylates	anticoagulant; antipyretic; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; drug allergen; EC 1.1.1.188 (prostaglandin-F synthase) inhibitor; geroprotector; non-narcotic analgesic; non-steroidal anti-inflammatory drug; plant activator; platelet aggregation inhibitor; prostaglandin antagonist; teratogenic agent	2000	2000	24.0	low	1
beta-naphthoflavone	1	extended flavonoid; naphtho-gamma-pyrone; organic heterotricyclic compound	aryl hydrocarbon receptor agonist	2000	2000	24.0	low	1
bumetanide	1	amino acid; benzoic acids; sulfonamide	diuretic; EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor	2000	2000	24.0	low	1
carbamazepine	1	dibenzoazepine; ureas	analgesic; anticonvulsant; antimanic drug; drug allergen; EC 3.5.1.98 (histone deacetylase) inhibitor; environmental contaminant; glutamate transporter activator; mitogen; non-narcotic analgesic; sodium channel blocker; xenobiotic	2000	2000	24.0	low	1
chlorpheniramine	1	monochlorobenzenes; pyridines; tertiary amino compound	anti-allergic agent; antidepressant; antipruritic drug; H1-receptor antagonist; histamine antagonist; serotonin uptake inhibitor	2000	2000	24.0	low	1
chlorpromazine	1	organochlorine compound; phenothiazines; tertiary amine	anticoronaviral agent; antiemetic; dopaminergic antagonist; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; phenothiazine antipsychotic drug	2000	2000	24.0	low	1
ciprofibrate	1	cyclopropanes; monocarboxylic acid; organochlorine compound	antilipemic drug	2000	2000	24.0	low	1
clofibrate	1	aromatic ether; ethyl ester; monochlorobenzenes	anticholesteremic drug; antilipemic drug; geroprotector; PPARalpha agonist	2000	2000	24.0	low	1
clofibric acid	1	aromatic ether; monocarboxylic acid; monochlorobenzenes	anticholesteremic drug; antilipemic drug; antineoplastic agent; herbicide; marine xenobiotic metabolite; PPARalpha agonist	2000	2000	24.0	low	1
4-chloro-N-(2,6-dimethyl-1-piperidinyl)-3-sulfamoylbenzamide	1	sulfonamide		2000	2000	24.0	low	1
4-cresol	1	cresol	Escherichia coli metabolite; human metabolite; uremic toxin	2000	2000	24.0	low	1
cyproheptadine	1	piperidines; tertiary amine	anti-allergic agent; antipruritic drug; gastrointestinal drug; H1-receptor antagonist; serotonergic antagonist	2000	2000	24.0	low	1
danthron	1	dihydroxyanthraquinone	apoptosis inducer; plant metabolite	2000	2000	24.0	low	1
dapsone	1	substituted aniline; sulfone	anti-inflammatory drug; antiinfective agent; antimalarial; leprostatic drug	2000	2000	24.0	low	1
decanoic acid	1	medium-chain fatty acid; straight-chain saturated fatty acid	algal metabolite; anti-inflammatory agent; antibacterial agent; human metabolite; plant metabolite; volatile oil component	2000	2000	24.0	low	1
desipramine	1	dibenzoazepine; secondary amino compound	adrenergic uptake inhibitor; alpha-adrenergic antagonist; antidepressant; cholinergic antagonist; drug allergen; EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; H1-receptor antagonist; serotonin uptake inhibitor	2000	2000	24.0	low	1
diflunisal	1	monohydroxybenzoic acid; organofluorine compound	non-narcotic analgesic; non-steroidal anti-inflammatory drug	2000	2000	24.0	low	1
diphenhydramine	1	ether; tertiary amino compound	anti-allergic agent; antidyskinesia agent; antiemetic; antiparkinson drug; antipruritic drug; antitussive; H1-receptor antagonist; local anaesthetic; muscarinic antagonist; oneirogen; sedative	2000	2000	24.0	low	1
valproic acid	1	branched-chain fatty acid; branched-chain saturated fatty acid	anticonvulsant; antimanic drug; EC 3.5.1.98 (histone deacetylase) inhibitor; GABA agent; neuroprotective agent; psychotropic drug; teratogenic agent	2000	2000	24.0	low	1
doxepin	1	dibenzooxepine; tertiary amino compound	antidepressant	2000	2000	24.0	low	1
doxylamine	1	pyridines; tertiary amine	anti-allergic agent; antiemetic; antitussive; cholinergic antagonist; H1-receptor antagonist; histamine antagonist; sedative	2000	2000	24.0	low	1
emodin	1	trihydroxyanthraquinone	antineoplastic agent; laxative; plant metabolite; tyrosine kinase inhibitor	2000	2000	24.0	low	1
ethacrynic acid	1	aromatic ether; aromatic ketone; dichlorobenzene; monocarboxylic acid	EC 2.5.1.18 (glutathione transferase) inhibitor; ion transport inhibitor; loop diuretic	2000	2000	24.0	low	1
fenoprofen	1	monocarboxylic acid	antipyretic; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; drug allergen; non-narcotic analgesic; non-steroidal anti-inflammatory drug	2000	2000	24.0	low	1
berotek	1	resorcinols; secondary alcohol; secondary amino compound	beta-adrenergic agonist; bronchodilator agent; sympathomimetic agent; tocolytic agent	2000	2000	24.0	low	1
fluphenazine	1	N-alkylpiperazine; organofluorine compound; phenothiazines	anticoronaviral agent; dopaminergic antagonist; phenothiazine antipsychotic drug	2000	2000	24.0	low	1
fluorescite	1	benzoic acids; cyclic ketone; hydroxy monocarboxylic acid; organic heterotricyclic compound; phenols; xanthene dye	fluorescent dye; radioopaque medium	2000	2000	24.0	low	1
furosemide	1	chlorobenzoic acid; furans; sulfonamide	environmental contaminant; loop diuretic; xenobiotic	2000	2000	24.0	low	1
ibuprofen	1	monocarboxylic acid	antipyretic; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; drug allergen; environmental contaminant; geroprotector; non-narcotic analgesic; non-steroidal anti-inflammatory drug; radical scavenger; xenobiotic	2000	2000	24.0	low	1
imipramine	1	dibenzoazepine	adrenergic uptake inhibitor; antidepressant; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor	2000	2000	24.0	low	1
indomethacin	1	aromatic ether; indole-3-acetic acids; monochlorobenzenes; N-acylindole	analgesic; drug metabolite; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; environmental contaminant; gout suppressant; non-steroidal anti-inflammatory drug; xenobiotic metabolite; xenobiotic	2000	2000	24.0	low	1
ketoprofen	1	benzophenones; oxo monocarboxylic acid	antipyretic; drug allergen; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; environmental contaminant; non-steroidal anti-inflammatory drug; xenobiotic	2000	2000	24.0	low	1
ketotifen	1	cyclic ketone; olefinic compound; organic heterotricyclic compound; organosulfur heterocyclic compound; piperidines; tertiary amino compound	anti-asthmatic drug; H1-receptor antagonist	2000	2000	24.0	low	1
labetalol	1	benzamides; benzenes; phenols; primary carboxamide; salicylamides; secondary alcohol; secondary amino compound		2000	2000	24.0	low	1
lamotrigine	1	1,2,4-triazines; dichlorobenzene; primary arylamine	anticonvulsant; antidepressant; antimanic drug; calcium channel blocker; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; environmental contaminant; excitatory amino acid antagonist; geroprotector; non-narcotic analgesic; xenobiotic	2000	2000	24.0	low	1
lauric acid	1	medium-chain fatty acid; straight-chain saturated fatty acid	algal metabolite; antibacterial agent; plant metabolite	2000	2000	24.0	low	1
lorazepam	1	benzodiazepine		2000	2000	24.0	low	1
losartan	1	biphenylyltetrazole; imidazoles	angiotensin receptor antagonist; anti-arrhythmia drug; antihypertensive agent; endothelin receptor antagonist	2000	2000	24.0	low	1
loxapine	1	dibenzooxazepine	antipsychotic agent; dopaminergic antagonist	2000	2000	24.0	low	1
meperidine	1	ethyl ester; piperidinecarboxylate ester; tertiary amino compound	antispasmodic drug; kappa-opioid receptor agonist; mu-opioid receptor agonist; opioid analgesic	2000	2000	24.0	low	1
mesalamine	1	amino acid; aromatic amine; monocarboxylic acid; monohydroxybenzoic acid; phenols	non-steroidal anti-inflammatory drug	2000	2000	24.0	low	1
mexiletine	1	aromatic ether; primary amino compound	anti-arrhythmia drug	2000	2000	24.0	low	1
mitoxantrone	1	dihydroxyanthraquinone	analgesic; antineoplastic agent	2000	2000	24.0	low	1
nortriptyline	1	organic tricyclic compound; secondary amine	adrenergic uptake inhibitor; analgesic; antidepressant; antineoplastic agent; apoptosis inducer; drug metabolite	2000	2000	24.0	low	1
oxazepam	1	1,4-benzodiazepinone; organochlorine compound	anxiolytic drug; environmental contaminant; xenobiotic	2000	2000	24.0	low	1
oxyphenbutazone	1	phenols; pyrazolidines	antimicrobial agent; antineoplastic agent; antipyretic; drug metabolite; gout suppressant; non-narcotic analgesic; non-steroidal anti-inflammatory drug; xenobiotic metabolite	2000	2000	24.0	low	1
aminosalicylic acid	1	aminobenzoic acid; phenols	antitubercular agent	2000	2000	24.0	low	1
pheniramine	1	pyridines; tertiary amino compound		2000	2000	24.0	low	1
phenobarbital	1	barbiturates	anticonvulsant; drug allergen; excitatory amino acid antagonist; sedative	2000	2000	24.0	low	1
phenolphthalein	1	phenols		2000	2000	24.0	low	1
phenolsulfonphthalein	1	2,1-benzoxathiole; arenesulfonate ester; phenols; sultone	acid-base indicator; diagnostic agent; two-colour indicator	2000	2000	24.0	low	1
phenylbutazone	1	pyrazolidines	antirheumatic drug; EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor; metabolite; non-narcotic analgesic; non-steroidal anti-inflammatory drug; peripheral nervous system drug	2000	2000	24.0	low	1
probenecid	1	benzoic acids; sulfonamide	uricosuric drug	2000	2000	24.0	low	1
promethazine	1	phenothiazines; tertiary amine	anti-allergic agent; anticoronaviral agent; antiemetic; antipruritic drug; H1-receptor antagonist; local anaesthetic; sedative	2000	2000	24.0	low	1
propofol	1	phenols	anticonvulsant; antiemetic; intravenous anaesthetic; radical scavenger; sedative	2000	2000	24.0	low	1
propranolol	1	naphthalenes; propanolamine; secondary amine	anti-arrhythmia drug; antihypertensive agent; anxiolytic drug; beta-adrenergic antagonist; environmental contaminant; human blood serum metabolite; vasodilator agent; xenobiotic	2000	2000	24.0	low	1
propyl gallate	1	trihydroxybenzoic acid		2000	2000	24.0	low	1
pyrilamine	1	aromatic ether; ethylenediamine derivative	H1-receptor antagonist	2000	2000	24.0	low	1
1,2,5,8-tetrahydroxy anthraquinone	1	tetrahydroxyanthraquinone	EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor	2000	2000	24.0	low	1
salicylamide	1	phenols; salicylamides	antirheumatic drug; non-narcotic analgesic	2000	2000	24.0	low	1
sulfadimethoxine	1	aromatic ether; pyrimidines; substituted aniline; sulfonamide antibiotic; sulfonamide	antiinfective agent; antimicrobial agent; drug allergen; environmental contaminant; xenobiotic	2000	2000	24.0	low	1
sulfathiazole	1	1,3-thiazoles; substituted aniline; sulfonamide antibiotic; sulfonamide	antiinfective agent; drug allergen; EC 2.5.1.15 (dihydropteroate synthase) inhibitor; environmental contaminant; xenobiotic	2000	2000	24.0	low	1
sulfinpyrazone	1	pyrazolidines; sulfoxide	uricosuric drug	2000	2000	24.0	low	1
suprofen	1	aromatic ketone; monocarboxylic acid; thiophenes	antirheumatic drug; drug allergen; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug; peripheral nervous system drug	2000	2000	24.0	low	1
temazepam	1	benzodiazepine		2000	2000	24.0	low	1
terfenadine	1	diarylmethane		2000	2000	24.0	low	1
thonzylamine	1	methoxybenzenes		2000	2000	24.0	low	1
tiaprofenic acid	1	aromatic ketone; monocarboxylic acid; thiophenes	drug allergen; non-steroidal anti-inflammatory drug	2000	2000	24.0	low	1
trifluoperazine	1	N-alkylpiperazine; N-methylpiperazine; organofluorine compound; phenothiazines	antiemetic; calmodulin antagonist; dopaminergic antagonist; EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor; EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor; phenothiazine antipsychotic drug	2000	2000	24.0	low	1
triflupromazine	1	organofluorine compound; phenothiazines; tertiary amine	anticoronaviral agent; antiemetic; dopaminergic antagonist; first generation antipsychotic	2000	2000	24.0	low	1
tripelennamine	1	aromatic amine		2000	2000	24.0	low	1
zomepirac	1	aromatic ketone; monocarboxylic acid; monochlorobenzenes; pyrroles	cardiovascular drug; non-steroidal anti-inflammatory drug	2000	2000	24.0	low	1
corticosterone	1	11beta-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(4) steroid; C21-steroid; glucocorticoid; primary alpha-hydroxy ketone	human metabolite; mouse metabolite	2000	2000	24.0	low	1
estriol	1	16alpha-hydroxy steroid; 17beta-hydroxy steroid; 3-hydroxy steroid	estrogen; human metabolite; human xenobiotic metabolite; mouse metabolite	2000	2000	24.0	low	1
2-aminophenol	1	aminophenol	bacterial metabolite	2000	2000	24.0	low	1
thyroxine	1	2-halophenol; iodophenol; L-phenylalanine derivative; non-proteinogenic L-alpha-amino acid; thyroxine zwitterion; thyroxine	antithyroid drug; human metabolite; mouse metabolite; thyroid hormone	2000	2000	24.0	low	1
aldosterone	1	11beta-hydroxy steroid; 18-oxo steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(4) steroid; C21-steroid hormone; mineralocorticoid; primary alpha-hydroxy ketone; steroid aldehyde	human metabolite; mouse metabolite	2000	2000	24.0	low	1
tetrahydrocortisol	1	11beta-hydroxy steroid; 17alpha-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3alpha-hydroxy steroid; glucocorticoid; primary alpha-hydroxy ketone; tertiary alpha-hydroxy ketone		2000	2000	24.0	low	1
prednisone	1	11-oxo steroid; 17alpha-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(1),Delta(4)-steroid; C21-steroid; glucocorticoid; primary alpha-hydroxy ketone; tertiary alpha-hydroxy ketone	adrenergic agent; anti-inflammatory drug; antineoplastic agent; immunosuppressive agent; prodrug	2000	2000	24.0	low	1
tetrahydrocortisone	1	21-hydroxy steroid		2000	2000	24.0	low	1
estrone	1	17-oxo steroid; 3-hydroxy steroid; phenolic steroid; phenols	antineoplastic agent; bone density conservation agent; estrogen; human metabolite; mouse metabolite	2000	2000	24.0	low	1
androsterone	1	17-oxo steroid; 3alpha-hydroxy steroid; androstanoid; C19-steroid	androgen; anticonvulsant; human blood serum metabolite; human metabolite; human urinary metabolite; mouse metabolite; pheromone	2000	2000	24.0	low	1
etiocholanolone	1	17-oxo steroid; 3alpha-hydroxy steroid; androstanoid	human metabolite; mouse metabolite	2000	2000	24.0	low	1
dehydroepiandrosterone	1	17-oxo steroid; 3beta-hydroxy-Delta(5)-steroid; androstanoid	androgen; human metabolite; mouse metabolite	2000	2000	24.0	low	1
hydroxyacetylaminofluorene	1	2-acetamidofluorenes		2000	2000	24.0	low	1
triiodothyronine	1	2-halophenol; amino acid zwitterion; iodophenol; iodothyronine	human metabolite; mouse metabolite; thyroid hormone	2000	2000	24.0	low	1
benz(a)anthracene	1	ortho-fused polycyclic arene; tetraphenes		2000	2000	24.0	low	1
chloramphenicol	1	C-nitro compound; carboxamide; diol; organochlorine compound	antibacterial drug; antimicrobial agent; Escherichia coli metabolite; geroprotector; Mycoplasma genitalium metabolite; protein synthesis inhibitor	2000	2000	24.0	low	1
ethinyl estradiol	1	17-hydroxy steroid; 3-hydroxy steroid; terminal acetylenic compound	xenoestrogen	2000	2000	24.0	low	1
aniline	1	anilines; primary arylamine		2000	2000	24.0	low	1
desoxycorticosterone	1	20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(4) steroid; mineralocorticoid; primary alpha-hydroxy ketone	human metabolite; mouse metabolite	2000	2000	24.0	low	1
norethindrone	1	17beta-hydroxy steroid; 3-oxo-Delta(4) steroid; terminal acetylenic compound; tertiary alcohol	progestin; synthetic oral contraceptive	2000	2000	24.0	low	1
norethynodrel	1	oxo steroid		2000	2000	24.0	low	1
17-alpha-hydroxyprogesterone	1	17alpha-hydroxy-C21-steroid; 17alpha-hydroxy steroid; tertiary alpha-hydroxy ketone	human metabolite; metabolite; mouse metabolite; progestin	2000	2000	24.0	low	1
ampicillin	1	beta-lactam antibiotic; penicillin allergen; penicillin	antibacterial drug	2000	2000	24.0	low	1
alizarin	1	dihydroxyanthraquinone	chromophore; dye; plant metabolite	2000	2000	24.0	low	1
linalool	1	monoterpenoid; tertiary alcohol	antimicrobial agent; fragrance; plant metabolite; volatile oil component	2000	2000	24.0	low	1
1,4-dihydroxyanthraquinone	1	dihydroxyanthraquinone	dye	2000	2000	24.0	low	1
cyclizine	1	N-alkylpiperazine	antiemetic; central nervous system depressant; cholinergic antagonist; H1-receptor antagonist; local anaesthetic	2000	2000	24.0	low	1
2,6-dihydroxyanthraquinone	1	dihydroxyanthraquinone	antimutagen; plant metabolite	2000	2000	24.0	low	1
9,10-anthraquinone	1	anthraquinone		2000	2000	24.0	low	1
thymol	1	monoterpenoid; phenols	volatile oil component	2000	2000	24.0	low	1
1-naphthol	1	naphthol	genotoxin; human xenobiotic metabolite	2000	2000	24.0	low	1
2-aminodiphenyl	1			2000	2000	24.0	low	1
2-phenylphenol	1	hydroxybiphenyls	antifungal agrochemical; environmental food contaminant	2000	2000	24.0	low	1
quinoline	1	azaarene; mancude organic heterobicyclic parent; ortho-fused heteroarene; quinolines		2000	2000	24.0	low	1
2-naphthylamine	1	naphthylamine	carcinogenic agent	2000	2000	24.0	low	1
4-biphenylamine	1	aminobiphenyl	carcinogenic agent	2000	2000	24.0	low	1
4-phenylphenol	1	hydroxybiphenyls		2000	2000	24.0	low	1
benzidine	1	biphenyls; substituted aniline	carcinogenic agent	2000	2000	24.0	low	1
4,4'-dihydroxybiphenyl	1	hydroxybiphenyls		2000	2000	24.0	low	1
propylparaben	1	benzoate ester; paraben; phenols	antifungal agent; antimicrobial agent	2000	2000	24.0	low	1
butylphen	1	phenols	allergen	2000	2000	24.0	low	1
methylparaben	1	paraben	antifungal agent; antimicrobial food preservative; neuroprotective agent; plant metabolite	2000	2000	24.0	low	1
4-isopropylphenol	1	phenols	flavouring agent	2000	2000	24.0	low	1
4-hydroxyacetophenone	1	monohydroxyacetophenone	fungal metabolite; mouse metabolite; plant metabolite	2000	2000	24.0	low	1
4-benzylphenol	1			2000	2000	24.0	medium	1
2-ethylhexanol	1	primary alcohol	plant metabolite; volatile oil component	2000	2000	24.0	low	1
2,2,2-trichloroethanol	1	chloroethanol	mouse metabolite	2000	2000	24.0	low	1
anthrarufin	1	dihydroxyanthraquinone		2000	2000	24.0	medium	1
2-toluic acid	1	methylbenzoic acid	xenobiotic metabolite	2000	2000	24.0	low	1
ethyl-p-hydroxybenzoate	1	ethyl ester; paraben	antifungal agent; antimicrobial food preservative; phytoestrogen; plant metabolite	2000	2000	24.0	low	1
3-tert-butyl-4-hydroxyanisole	1	aromatic ether; phenols	antioxidant; human xenobiotic metabolite	2000	2000	24.0	low	1
1-naphthylamine	1	naphthylamine	human xenobiotic metabolite	2000	2000	24.0	low	1
2-naphthol	1	naphthol	antinematodal drug; genotoxin; human urinary metabolite; human xenobiotic metabolite; mouse metabolite; radical scavenger	2000	2000	24.0	low	1
shikimic acid	1	alpha,beta-unsaturated monocarboxylic acid; cyclohexenecarboxylic acid; hydroxy monocarboxylic acid	Escherichia coli metabolite; plant metabolite; Saccharomyces cerevisiae metabolite	2000	2000	24.0	low	1
citronellol	1	monoterpenoid	plant metabolite	2000	2000	24.0	low	1
hexanoic acid	1	medium-chain fatty acid; straight-chain saturated fatty acid	human metabolite; plant metabolite	2000	2000	24.0	low	1
pregnenolone	1	20-oxo steroid; 3beta-hydroxy-Delta(5)-steroid; C21-steroid	human metabolite; mouse metabolite	2000	2000	24.0	low	1
ditiocarb	1	dithiocarbamic acids	chelator; copper chelator	2000	2000	24.0	low	1
mequinol	1	methoxybenzenes; phenols	metabolite	2000	2000	24.0	low	1
catechin	1	catechin	antioxidant; plant metabolite	2000	2000	24.0	low	1
phenetidine	1	aromatic ether; primary amino compound; substituted aniline	drug metabolite	2000	2000	24.0	low	1
4-hydroxyphenobarbital	1	barbiturates		2000	2000	24.0	low	1
lithocholic acid	1	bile acid; C24-steroid; monohydroxy-5beta-cholanic acid	geroprotector; human metabolite; mouse metabolite	2000	2000	24.0	low	1
chenodeoxycholic acid	1	bile acid; C24-steroid; dihydroxy-5beta-cholanic acid	human metabolite; mouse metabolite	2000	2000	24.0	low	1
epitestosterone	1	17alpha-hydroxy steroid; 3-oxo-Delta(4) steroid; androstanoid	androgen antagonist; human metabolite	2000	2000	24.0	low	1
chrysophanic acid	1	dihydroxyanthraquinone	anti-inflammatory agent; antiviral agent; plant metabolite	2000	2000	24.0	low	1
carvacrol	1	botanical anti-fungal agent; p-menthane monoterpenoid; phenols	agrochemical; antimicrobial agent; flavouring agent; TRPA1 channel agonist; volatile oil component	2000	2000	24.0	low	1
androstenediol	1	17beta-hydroxy steroid; 3beta-hydroxy-Delta(5)-steroid	androgen; human metabolite; mouse metabolite; radiation protective agent	2000	2000	24.0	low	1
dihydrotestosterone	1	17beta-hydroxy steroid; 17beta-hydroxyandrostan-3-one; 3-oxo-5alpha-steroid	androgen; Daphnia magna metabolite; human metabolite; mouse metabolite	2000	2000	24.0	low	1
1,2,3,4-tetrahydro-1-naphthalenol	1			2000	2000	24.0	medium	1
4-iodophenol	1	iodophenol		2000	2000	24.0	low	1
myristic acid	1	long-chain fatty acid; straight-chain saturated fatty acid	algal metabolite; Daphnia magna metabolite; EC 3.1.1.1 (carboxylesterase) inhibitor; human metabolite	2000	2000	24.0	low	1
4-methyl-1-(1-methylethyl)-3-cyclohexen-1-ol	1	terpineol; tertiary alcohol	anti-inflammatory agent; antibacterial agent; antineoplastic agent; antioxidant; antiparasitic agent; apoptosis inducer; plant metabolite; volatile oil component	2000	2000	24.0	low	1
3-hydroxyflavone	1	flavonols; monohydroxyflavone		2000	2000	24.0	low	1
6-hydroxyquinoline	1	monohydroxyquinoline		2000	2000	24.0	low	1
3-hydroxybiphenyl	1	hydroxybiphenyls		2000	2000	24.0	medium	1
diphenylamine	1	aromatic amine; bridged diphenyl fungicide; secondary amino compound	antifungal agrochemical; antioxidant; carotogenesis inhibitor; EC 1.3.99.29 [phytoene desaturase (zeta-carotene-forming)] inhibitor; ferroptosis inhibitor; radical scavenger	2000	2000	24.0	low	1
alpha-naphthoflavone	1	extended flavonoid; naphtho-gamma-pyrone; organic heterotricyclic compound	aryl hydrocarbon receptor agonist; aryl hydrocarbon receptor antagonist; EC 1.14.14.14 (aromatase) inhibitor	2000	2000	24.0	low	1
4-propylphenol	1	alkylbenzene		2000	2000	24.0	medium	1
hexafluoroisopropanol	1	organofluorine compound; secondary alcohol	drug metabolite	2000	2000	24.0	low	1
d-alpha tocopherol	1	alpha-tocopherol	algal metabolite; antiatherogenic agent; anticoagulant; antioxidant; antiviral agent; EC 2.7.11.13 (protein kinase C) inhibitor; immunomodulator; micronutrient; nutraceutical; plant metabolite	2000	2000	24.0	low	1
fenchol	1			2000	2000	24.0	low	1
4-n-Butylphenol	1	phenols		2000	2000	24.0	high	1
4-hydroxyazobenzene	1			2000	2000	24.0	low	1
4-nitrothiophenolate	1			2000	2000	24.0	low	1
5 alpha-androstane-3 alpha,17 beta-diol	1	androstane-3alpha,17beta-diol	Daphnia magna metabolite; human metabolite	2000	2000	24.0	low	1
menthol	1	p-menthan-3-ol	antipruritic drug; antispasmodic drug; antitussive	2000	2000	24.0	low	1
hydroxyphenytoin	1	imidazolidine-2,4-dione; phenols	metabolite	2000	2000	24.0	low	1
mono-(2-ethylhexyl)phthalate	1	phthalic acid monoester		2000	2000	24.0	low	1
1-naphthalenemethanol	1	naphthylmethanol	mouse metabolite	2000	2000	24.0	medium	1
dexpropranolol	1	propranolol		2000	2000	24.0	low	1
butylated hydroxyanisole	1			2000	2000	24.0	low	1
3-hydroxybenzo(a)pyrene	1	ortho- and peri-fused polycyclic arene		2000	2000	24.0	low	1
4-n-Pentylphenol	1	phenols		2000	2000	24.0	medium	1
9-hydroxybenzo(a)pyrene	1	ortho- and peri-fused polycyclic arene		2000	2000	24.0	low	1
daunorubicin	1	aminoglycoside antibiotic; anthracycline; p-quinones; tetracenequinones	antineoplastic agent; bacterial metabolite	2000	2000	24.0	low	1
n-phenylethanolamine	1	aralkylamine		2000	2000	24.0	low	1
4-ethylphenol	1	phenols	fungal xenobiotic metabolite	2000	2000	24.0	low	1
ursodeoxycholic acid	1	bile acid; C24-steroid; dihydroxy-5beta-cholanic acid	human metabolite; mouse metabolite	2000	2000	24.0	low	1
pregnanolone	1	3-hydroxy-5beta-pregnan-20-one; 3alpha-hydroxy steroid	human metabolite; intravenous anaesthetic; sedative	2000	2000	24.0	low	1
butylated hydroxytoluene	1	phenols	antioxidant; ferroptosis inhibitor; food additive; geroprotector	2000	2000	24.0	low	1
zidovudine	1	azide; pyrimidine 2',3'-dideoxyribonucleoside	antimetabolite; antiviral drug; HIV-1 reverse transcriptase inhibitor	2000	2000	24.0	low	1
6-hydroxybenzo(a)pyrene	1	ortho- and peri-fused polycyclic arene		2000	2000	24.0	high	1
dexibuprofen	1	ibuprofen	non-narcotic analgesic; non-steroidal anti-inflammatory drug	2000	2000	24.0	low	1
benoxaprofen	1	1,3-benzoxazoles; monocarboxylic acid; monochlorobenzenes	antipsoriatic; antipyretic; EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor; hepatotoxic agent; nephrotoxin; non-narcotic analgesic; non-steroidal anti-inflammatory drug; protein kinase C agonist	2000	2000	24.0	low	1
2-hydroxybenzo(a)pyrene	1	ortho- and peri-fused polycyclic arene		2000	2000	24.0	medium	1
octyl gallate	1	gallate ester	food antioxidant; hypoglycemic agent; plant metabolite	2000	2000	24.0	low	1
4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol	1	stilbenoid		2000	2000	24.0	low	1
2',7'-dichlorofluorescein	1	2-benzofurans	fluorochrome	2000	2000	24.0	low	1
16-hydroxytestosterone	1	16alpha-hydroxy steroid; 17beta-hydroxy steroid; 3-oxo-Delta(4) steroid; androstanoid; C19-steroid; diol; secondary alcohol	androgen	2000	2000	24.0	medium	1
2-methoxyestradiol	1	17beta-hydroxy steroid; 3-hydroxy steroid	angiogenesis modulating agent; antimitotic; antineoplastic agent; human metabolite; metabolite; mouse metabolite	2000	2000	24.0	low	1
5,6,7,8-tetrahydro-1-naphthol	1	tetralins		2000	2000	24.0	medium	1
alfatradiol	1	17alpha-hydroxy steroid; 3-hydroxy steroid; estradiol	estrogen; geroprotector	2000	2000	24.0	medium	1
4-hydroxyquinoline	1	monohydroxyquinoline; quinolone		2000	2000	24.0	low	1
17-alpha-hydroxypregnenolone	1	17alpha-hydroxy-C21-steroid; 17alpha-hydroxy steroid; 3beta-hydroxy-Delta(5)-steroid; hydroxypregnenolone; tertiary alpha-hydroxy ketone	human metabolite; mouse metabolite	2000	2000	24.0	low	1
5-(3-hydroxyphenyl)-5-phenylhydantoin	1			2000	2000	24.0	low	1
7-amino-4-methylcoumarin	1	7-aminocoumarins	fluorochrome	2000	2000	24.0	low	1
11-hydroxyprogesterone, (11alpha)-isomer	1	11alpha-hydroxy steroid; 20-oxo steroid; 3-oxo-Delta(4) steroid		2000	2000	24.0	low	1
brexanolone	1	3-hydroxy-5alpha-pregnan-20-one	antidepressant; GABA modulator; human metabolite; intravenous anaesthetic; sedative	2000	2000	24.0	low	1
3,5-diiodothyronine, (l)-isomer	1	phenylalanine derivative		2000	2000	24.0	medium	1
harmol hydrochloride	1			2000	2000	24.0	medium	1
diosgenin	1	3beta-sterol; hexacyclic triterpenoid; sapogenin; spiroketal	antineoplastic agent; antiviral agent; apoptosis inducer; metabolite	2000	2000	24.0	low	1
sarsasapogenin, (3beta,5alpha,25r)-isomer	1	sapogenin	gout suppressant; plant metabolite	2000	2000	24.0	medium	1
3 alpha,17 alpha-dihydroxy-5 beta-pregnan-20-one	1	17alpha-hydroxy steroid; 20-oxo steroid; 3alpha-hydroxy steroid; C21-steroid; corticosteroid hormone	human urinary metabolite	2000	2000	24.0	medium	1
2-methoxyestriol	1			2000	2000	24.0	low	1
2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine	1	hydroxylamine; imidazopyridine	carcinogenic agent; genotoxin; human xenobiotic metabolite; mouse metabolite; mutagen; neurotoxin; rat metabolite	2000	2000	24.0	low	1
ecopipam	1	benzazepine		2000	2000	24.0	low	1
ibuprofen, (r)-isomer	1	ibuprofen		2000	2000	24.0	medium	1
11-hydroxytestosterone	1	11beta-hydroxy steroid; 17beta-hydroxy steroid; 3-oxo-Delta(4) steroid; androstanoid; C19-steroid	bacterial xenobiotic metabolite; human xenobiotic metabolite; marine metabolite	2000	2000	24.0	low	1
norbuprenorphine	1	phenanthrenes		2000	2000	24.0	low	1
benzo(a)pyrene-3,6-quinol	1			2000	2000	24.0	high	1
naproxen	1	methoxynaphthalene; monocarboxylic acid	antipyretic; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; drug allergen; environmental contaminant; gout suppressant; non-narcotic analgesic; non-steroidal anti-inflammatory drug; xenobiotic	2000	2000	24.0	low	1
cortolone	1	21-hydroxy steroid		2000	2000	24.0	low	1
carbocysteine	1	L-cysteine thioether; non-proteinogenic L-alpha-amino acid	mucolytic	2000	2000	24.0	low	1
cholic acid	1	12alpha-hydroxy steroid; 3alpha-hydroxy steroid; 7alpha-hydroxy steroid; bile acid; C24-steroid; trihydroxy-5beta-cholanic acid	human metabolite; mouse metabolite	2000	2000	24.0	low	1
5 alpha-androstane-3 beta,17 beta-diol	1	17beta-hydroxy steroid; 3beta-hydroxy steroid; androstane-3,17-diol	Daphnia magna metabolite; human metabolite	2000	2000	24.0	low	1
cortol	1	21-hydroxy steroid		2000	2000	24.0	medium	1
21-hydroxypregnenolone	1	21-hydroxy steroid; hydroxypregnenolone; primary alpha-hydroxy ketone	mouse metabolite	2000	2000	24.0	medium	1
2-hydroxyestradiol	1	17beta-hydroxy steroid; 2-hydroxy steroid	carcinogenic agent; human metabolite; metabolite; mouse metabolite; prodrug	2000	2000	24.0	low	1
epietiocholanolone	1	17-oxo steroid; 3beta-hydroxy steroid; androstanoid	androgen; animal metabolite; human blood serum metabolite; mouse metabolite; rat metabolite	2000	2000	24.0	medium	1
naringenin	1	(2S)-flavan-4-one; naringenin	expectorant; plant metabolite	2000	2000	24.0	low	1
2-hydroxyestrone	1	2-hydroxy steroid; catechols	human metabolite	2000	2000	24.0	low	1
epiandrosterone	1	17-oxo steroid; 3beta-hydroxy steroid; androstanoid	androgen; human metabolite	2000	2000	24.0	low	1
naringin	1	(2S)-flavan-4-one; 4'-hydroxyflavanones; dihydroxyflavanone; disaccharide derivative; neohesperidoside	anti-inflammatory agent; antineoplastic agent; metabolite	2000	2000	24.0	low	1
1-alpha-terpineol	1	alpha-terpineol	plant metabolite	2000	2000	24.0	medium	1
diprenorphine	1	morphinane alkaloid		2000	2000	24.0	low	1
ergosterol	1	3beta-hydroxy-Delta(5)-steroid; 3beta-sterol; ergostanoid; phytosterols	fungal metabolite; Saccharomyces cerevisiae metabolite	2000	2000	24.0	low	1
tretinoin	1	retinoic acid; vitamin A	anti-inflammatory agent; antineoplastic agent; antioxidant; AP-1 antagonist; human metabolite; keratolytic drug; retinoic acid receptor agonist; retinoid X receptor agonist; signalling molecule	2000	2000	24.0	low	1
retinol	1	retinol; vitamin A	human metabolite; mouse metabolite; plant metabolite	2000	2000	24.0	low	1
ferulic acid	1	ferulic acids	anti-inflammatory agent; antioxidant; apoptosis inhibitor; cardioprotective agent; MALDI matrix material; plant metabolite	2000	2000	24.0	low	1
mycophenolic acid	1	2-benzofurans; gamma-lactone; monocarboxylic acid; phenols	anticoronaviral agent; antimicrobial agent; antineoplastic agent; EC 1.1.1.205 (IMP dehydrogenase) inhibitor; environmental contaminant; immunosuppressive agent; mycotoxin; Penicillium metabolite; xenobiotic	2000	2000	24.0	low	1
diethylstilbestrol	1	olefinic compound; polyphenol	antifungal agent; antineoplastic agent; autophagy inducer; calcium channel blocker; carcinogenic agent; EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor; EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor; endocrine disruptor; xenoestrogen	2000	2000	24.0	low	1
geraniol	1	3,7-dimethylocta-2,6-dien-1-ol; monoterpenoid; primary alcohol	allergen; fragrance; plant metabolite; volatile oil component	2000	2000	24.0	low	1
dienestrol	1			2000	2000	24.0	low	1
captax	1	aryl thiol; benzothiazoles	carcinogenic agent; metabolite	2000	2000	24.0	low	1
thiothixene	1	N-methylpiperazine	anticoronaviral agent	2000	2000	24.0	low	1
chlorogenic acid	1	cinnamate ester; tannin	food component; plant metabolite	2000	2000	24.0	low	1
sch 23390	1	benzazepine		2000	2000	24.0	low	1
digitoxigenin	1	14beta-hydroxy steroid; 3beta-hydroxy steroid		2000	2000	24.0	low	1
quercetin	1	7-hydroxyflavonol; pentahydroxyflavone	antibacterial agent; antineoplastic agent; antioxidant; Aurora kinase inhibitor; chelator; EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor; geroprotector; phytoestrogen; plant metabolite; protein kinase inhibitor; radical scavenger	2000	2000	24.0	low	1
bilirubin	1	biladienes; dicarboxylic acid	antioxidant; human metabolite; mouse metabolite	2000	2000	24.0	low	1
apigenin	1	trihydroxyflavone	antineoplastic agent; metabolite	2000	2000	24.0	low	1
scopoletin	1	hydroxycoumarin	plant growth regulator; plant metabolite	2000	2000	24.0	low	1
hymecromone	1	hydroxycoumarin	antineoplastic agent; hyaluronic acid synthesis inhibitor	2000	2000	24.0	low	1
vitamin d 2	1	hydroxy seco-steroid; seco-ergostane; vitamin D	bone density conservation agent; nutraceutical; plant metabolite; rodenticide	2000	2000	24.0	low	1
cholecalciferol	1	D3 vitamins; hydroxy seco-steroid; seco-cholestane; secondary alcohol; steroid hormone	geroprotector; human metabolite	2000	2000	24.0	low	1
esculetin	1	hydroxycoumarin	antioxidant; plant metabolite; ultraviolet filter	2000	2000	24.0	low	1
7-hydroxycoumarin	1	hydroxycoumarin	fluorescent probe; food component; plant metabolite	2000	2000	24.0	low	1
baicalein	1	trihydroxyflavone	angiogenesis inhibitor; anti-inflammatory agent; antibacterial agent; anticoronaviral agent; antifungal agent; antineoplastic agent; antioxidant; apoptosis inducer; EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor; EC 4.1.1.17 (ornithine decarboxylase) inhibitor; ferroptosis inhibitor; geroprotector; hormone antagonist; plant metabolite; prostaglandin antagonist; radical scavenger	2000	2000	24.0	low	1
chrysin	1	7-hydroxyflavonol; dihydroxyflavone	anti-inflammatory agent; antineoplastic agent; antioxidant; EC 2.7.11.18 (myosin-light-chain kinase) inhibitor; hepatoprotective agent; plant metabolite	2000	2000	24.0	low	1
fisetin	1	3'-hydroxyflavonoid; 7-hydroxyflavonol; tetrahydroxyflavone	anti-inflammatory agent; antioxidant; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; geroprotector; metabolite; plant metabolite	2000	2000	24.0	low	1
galangin	1	7-hydroxyflavonol; trihydroxyflavone	antimicrobial agent; EC 3.1.1.3 (triacylglycerol lipase) inhibitor; plant metabolite	2000	2000	24.0	low	1
4-hydroxyestradiol	1	4-hydroxy steroid	metabolite	2000	2000	24.0	low	1
isotretinoin	1	retinoic acid	antineoplastic agent; keratolytic drug; teratogenic agent	2000	2000	24.0	low	1
hyodeoxycholic acid	1	5beta-cholanic acids; 6alpha,20xi-murideoxycholic acid; bile acid; C24-steroid	human metabolite; mouse metabolite	2000	2000	24.0	low	1
codeine	1	morphinane alkaloid; organic heteropentacyclic compound	antitussive; drug allergen; environmental contaminant; opioid analgesic; opioid receptor agonist; prodrug; xenobiotic	2000	2000	24.0	low	1
hydromorphone	1	morphinane alkaloid; organic heteropentacyclic compound	mu-opioid receptor agonist; opioid analgesic	2000	2000	24.0	low	1
nalmefene	1	morphinane alkaloid		2000	2000	24.0	low	1
nalorphine	1	morphinane alkaloid		2000	2000	24.0	low	1
naloxone	1	morphinane alkaloid; organic heteropentacyclic compound; tertiary alcohol	antidote to opioid poisoning; central nervous system depressant; mu-opioid receptor antagonist	2000	2000	24.0	low	1
oxycodone	1	organic heteropentacyclic compound; semisynthetic derivative	antitussive; mu-opioid receptor agonist; opioid analgesic	2000	2000	24.0	low	1
oxymorphone	1	morphinane alkaloid		2000	2000	24.0	low	1
6alpha-hydroxy-17beta-estradiol	1	6alpha-hydroxy steroid		2000	2000	24.0	medium	1
morphine	1	morphinane alkaloid; organic heteropentacyclic compound; tertiary amino compound	anaesthetic; drug allergen; environmental contaminant; geroprotector; mu-opioid receptor agonist; opioid analgesic; plant metabolite; vasodilator agent; xenobiotic	2000	2000	24.0	low	1
nalbuphine	1	organic heteropentacyclic compound	mu-opioid receptor antagonist; opioid analgesic	2000	2000	24.0	low	1
cinnamyl alcohol	1	cinnamyl alcohol	plant metabolite	2000	2000	24.0	low	1
levorphanol	1	morphinane alkaloid		2000	2000	24.0	low	1
naltrexone	1	cyclopropanes; morphinane-like compound; organic heteropentacyclic compound	antidote to opioid poisoning; central nervous system depressant; environmental contaminant; mu-opioid receptor antagonist; xenobiotic	2000	2000	24.0	low	1
normorphine	1	morphinane alkaloid		2000	2000	24.0	low	1
naltrindole benzofuran	1	morphinane alkaloid		2000	2000	24.0	low	1
naltrindole	1	isoquinolines		2000	2000	24.0	low	1
19-hydroxycholesterol	1	cholestanoid		2000	2000	24.0	medium	1
borneol	1	borneol		2000	2000	24.0	medium	1
norcodeine	1	morphinane alkaloid		2000	2000	24.0	low	1
4-hydroxyestrone	1	17-oxo steroid; 3-hydroxy steroid; 4-hydroxy steroid; catechols; phenolic steroid	carcinogenic agent; estrogen; human urinary metabolite	2000	2000	24.0	low	1
2-hydroxyestriol	1			2000	2000	24.0	low	1
novobiocin	1	carbamate ester; ether; hexoside; hydroxycoumarin; monocarboxylic acid amide; monosaccharide derivative; phenols	antibacterial agent; antimicrobial agent; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; Escherichia coli metabolite; hepatoprotective agent	2000	2000	24.0	low	1
tetracycline	1			2000	2000	24.0	low	1
4-hydroxycoumarin	1	hydroxycoumarin		2000	2000	24.0	low	1
rifampin	1	cyclic ketal; hydrazone; N-iminopiperazine; N-methylpiperazine; rifamycins; semisynthetic derivative; zwitterion	angiogenesis inhibitor; antiamoebic agent; antineoplastic agent; antitubercular agent; DNA synthesis inhibitor; EC 2.7.7.6 (RNA polymerase) inhibitor; Escherichia coli metabolite; geroprotector; leprostatic drug; neuroprotective agent; pregnane X receptor agonist; protein synthesis inhibitor	2000	2000	24.0	low	1
clozapine	1	benzodiazepine; N-arylpiperazine; N-methylpiperazine; organochlorine compound	adrenergic antagonist; dopaminergic antagonist; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; environmental contaminant; GABA antagonist; histamine antagonist; muscarinic antagonist; second generation antipsychotic; serotonergic antagonist; xenobiotic	2000	2000	24.0	low	1
norclozapine	1	dibenzodiazepine; organochlorine compound; piperazines	delta-opioid receptor agonist; metabolite; serotonergic antagonist	2000	2000	24.0	low	1

Substance	Studies	Classes	Roles	First Year	Last Year	Average Age	Relationship Strength	pre-1990	1990's	2000's	2010's
ibuprofen	1	monocarboxylic acid	antipyretic; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; drug allergen; environmental contaminant; geroprotector; non-narcotic analgesic; non-steroidal anti-inflammatory drug; radical scavenger; xenobiotic	1982	1982	42.0	low	1	0	0	0
metyrapone	1	aromatic ketone	antimetabolite; diagnostic agent; EC 1.14.15.4 (steroid 11beta-monooxygenase) inhibitor	1984	1984	40.0	low	1	0	0	0
corticosterone	4	11beta-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(4) steroid; C21-steroid; glucocorticoid; primary alpha-hydroxy ketone	human metabolite; mouse metabolite	1975	2016	29.0	low	2	0	1	1
prednisolone	1	11beta-hydroxy steroid; 17alpha-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(1),Delta(4)-steroid; C21-steroid; glucocorticoid; primary alpha-hydroxy ketone; tertiary alpha-hydroxy ketone	adrenergic agent; anti-inflammatory drug; antineoplastic agent; drug metabolite; environmental contaminant; immunosuppressive agent; xenobiotic	2017	2017	7.0	low	0	0	0	1
estriol	1	16alpha-hydroxy steroid; 17beta-hydroxy steroid; 3-hydroxy steroid	estrogen; human metabolite; human xenobiotic metabolite; mouse metabolite	2009	2009	15.0	low	0	0	1	0
tetrahydrocortisol	3	11beta-hydroxy steroid; 17alpha-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3alpha-hydroxy steroid; glucocorticoid; primary alpha-hydroxy ketone; tertiary alpha-hydroxy ketone		1975	1985	43.3	low	3	0	0	0
tetrahydrocortisone	3	21-hydroxy steroid		1982	2012	24.7	low	1	0	1	1
estrone	1	17-oxo steroid; 3-hydroxy steroid; phenolic steroid; phenols	antineoplastic agent; bone density conservation agent; estrogen; human metabolite; mouse metabolite	2004	2004	20.0	low	0	0	1	0
androsterone	25	17-oxo steroid; 3alpha-hydroxy steroid; androstanoid; C19-steroid	androgen; anticonvulsant; human blood serum metabolite; human metabolite; human urinary metabolite; mouse metabolite; pheromone	1962	2019	28.7	low	13	2	3	7
etiocholanolone	14	17-oxo steroid; 3alpha-hydroxy steroid; androstanoid	human metabolite; mouse metabolite	1962	2019	34.6	low	10	0	1	3
dehydroepiandrosterone	7	17-oxo steroid; 3beta-hydroxy-Delta(5)-steroid; androstanoid	androgen; human metabolite; mouse metabolite	1982	2009	33.9	low	5	0	2	0
androstenedione	1	17-oxo steroid; 3-oxo-Delta(4) steroid; androstanoid	androgen; Daphnia magna metabolite; human metabolite; mouse metabolite	1985	1985	39.0	low	1	0	0	0
17-alpha-hydroxyprogesterone	1	17alpha-hydroxy-C21-steroid; 17alpha-hydroxy steroid; tertiary alpha-hydroxy ketone	human metabolite; metabolite; mouse metabolite; progestin	2012	2012	12.0	low	0	0	0	1
dehydroepiandrosterone sulfate	1	17-oxo steroid; steroid sulfate	EC 2.7.1.33 (pantothenate kinase) inhibitor; human metabolite; mouse metabolite	1984	1984	40.0	low	1	0	0	0
bromocriptine	1	indole alkaloid	antidyskinesia agent; antiparkinson drug; dopamine agonist; hormone antagonist	1984	1984	40.0	low	1	0	0	0
fludrocortisone	1	11beta-hydroxy steroid; 17alpha-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(4) steroid; C21-steroid; fluorinated steroid; mineralocorticoid	adrenergic agent; anti-inflammatory drug	2017	2017	7.0	low	0	0	0	1
tetrahydrocorticosterone	2	21-hydroxy steroid		1975	1985	44.0	low	2	0	0	0
tetrahydro-11-deoxycortisol	3	21-hydroxy steroid		1984	2017	22.3	low	1	0	1	1
17-alpha-hydroxypregnenolone	1	17alpha-hydroxy-C21-steroid; 17alpha-hydroxy steroid; 3beta-hydroxy-Delta(5)-steroid; hydroxypregnenolone; tertiary alpha-hydroxy ketone	human metabolite; mouse metabolite	2017	2017	7.0	low	0	0	0	1
allotetrahydrocortisol	1	corticosteroid hormone		1985	1985	39.0	low	1	0	0	0
11-ketoetiocholanolone	5	3-hydroxy steroid	androgen	1981	2019	29.2	high	3	0	1	1
pregnanetriol	7	corticosteroid hormone		1975	2019	27.6	low	4	0	0	3
11-hydroxyandrostenedione	1	3-hydroxy steroid	androgen	1985	1985	39.0	low	1	0	0	0
16-hydroxydehydroepiandrosterone sulfate	1			2009	2009	15.0	low	0	0	1	0
cortol	1	21-hydroxy steroid		2004	2004	20.0	medium	0	0	1	0
pregnanetriolone	2	corticosteroid hormone		2012	2017	9.5	medium	0	0	0	2
cortodoxone	3	deoxycortisol; glucocorticoid; primary alpha-hydroxy ketone; tertiary alpha-hydroxy ketone	human metabolite; mouse metabolite	1984	2017	22.3	low	1	0	1	1
17-ketosteroids	6			1962	1988	45.0	low	6	0	0	0
pregnanediol	4			1975	2012	35.8	low	3	0	0	1
5-androstene-3,16,17-triol	1	3-hydroxy steroid	androgen	2004	2004	20.0	medium	0	0	1	0

Condition	Studies	First Year	Last Year	Average Age	Relationship Strength	pre-1990	1990's	2000's	2010's
7-Dehydrocholesterol Reductase Deficiency	1	2009	2009	15.0	low	0	0	1	0
Acromegaly	1	1984	1984	40.0	low	1	0	0	0
Adenoma	2	1982	1984	41.0	low	2	0	0	0
Adenoma, Acidophil	1	1984	1984	40.0	low	1	0	0	0
Adenoma, Basal Cell	2	1982	1984	41.0	low	2	0	0	0
Adrenal Cancer	1	1984	1984	40.0	low	1	0	0	0
Adrenal Cortex Cancer	2	1982	1999	33.5	low	1	1	0	0
Adrenal Cortex Neoplasms	2	1982	1999	33.5	low	1	1	0	0
Adrenal Hyperplasia, Congenital	4	2012	2018	8.0	low	0	0	0	4
Aging	1	1975	1975	49.0	low	1	0	0	0
Alloxan Diabetes	1	1984	1984	40.0	low	1	0	0	0
Ambiguous Genitalia	1	1985	1985	39.0	low	1	0	0	0
Androgenization	2	1988	1999	30.5	low	1	1	0	0
Arthritis, Rheumatoid	1	1984	1984	40.0	low	1	0	0	0
Benign Neoplasms	1	2000	2000	24.0	low	0	1	0	0
Bilirubinemia	1	2000	2000	24.0	low	0	1	0	0
Body Weight	2	1984	2017	23.5	low	1	0	0	1
Breast Cancer	1	1975	1975	49.0	low	1	0	0	0
Breast Neoplasms	1	1975	1975	49.0	low	1	0	0	0
Cancer of Ovary	1	1988	1988	36.0	low	1	0	0	0
Cancer of Pituitary	1	1984	1984	40.0	low	1	0	0	0
Cancer of the Uterus	2	1975	2004	34.5	low	1	0	1	0
Carcinoma	1	1984	1984	40.0	low	1	0	0	0
Carcinoma, Anaplastic	1	1984	1984	40.0	low	1	0	0	0
Complications, Neoplastic Pregnancy	1	1988	1988	36.0	low	1	0	0	0
Congenital Adrenal Hyperplasia	4	2012	2018	8.0	low	0	0	0	4
Cystic Fibrosis	1	1981	1981	43.0	low	1	0	0	0
Cystic Fibrosis of Pancreas	1	1981	1981	43.0	low	1	0	0	0
Disorders of Sex Development	1	1985	1985	39.0	low	1	0	0	0
Ectopic Hormone Syndromes	1	1982	1982	42.0	low	1	0	0	0
Familial Precocious Puberty	1	1999	1999	25.0	low	0	1	0	0
Fibroid	1	2004	2004	20.0	low	0	0	1	0
Growth Disorders	1	1999	1999	25.0	low	0	1	0	0
Ichthyosis, Sex-Linked	1	2009	2009	15.0	low	0	0	1	0
Inappropriate GH Secretion Syndrome (Acromegaly)	1	1984	1984	40.0	low	1	0	0	0
Leiomyoma	1	2004	2004	20.0	low	0	0	1	0
Menopause	1	1975	1975	49.0	low	1	0	0	0
Necrosis	1	1999	1999	25.0	low	0	1	0	0
Neoplasms	1	2000	2000	24.0	low	0	1	0	0
Ovarian Neoplasms	1	1988	1988	36.0	low	1	0	0	0
Pituitary Neoplasms	1	1984	1984	40.0	low	1	0	0	0
Pregnancy	3	1980	2009	31.7	low	2	0	1	0
Puberty, Precocious	1	1999	1999	25.0	low	0	1	0	0
Rheumatoid Arthritis	1	1984	1984	40.0	low	1	0	0	0
Smith-Lemli-Opitz Syndrome	1	2009	2009	15.0	low	0	0	1	0
Stunted Growth	1	1999	1999	25.0	low	0	1	0	0
Theca Cell Tumor	1	1988	1988	36.0	low	1	0	0	0
Uremia	1	1986	1986	38.0	low	1	0	0	0
Uterine Neoplasms	2	1975	2004	34.5	low	1	0	1	0

Dosage (2)

Article	Year
The urinary steroidome of treated children with classic 21-hydroxylase deficiency. The Journal of steroid biochemistry and molecular biology, , Volume: 165, Issue:Pt B	2017
Effect of testosterone on maturational gonadotropin subunit messenger ribonucleic acid levels in the goldfish pituitary. Biology of reproduction, , Volume: 54, Issue:6	1996

11 beta-hydroxyandrosterone

Description

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Synonyms (42)

Roles (1)

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