A substance which lowers the surface tension of the medium in which it is dissolved, and/or the interfacial tension with other phases, and, accordingly, is positively adsorbed at the liquid/vapour and/or at other interfaces.
ChEBI ID: 35195
| Member | Definition | Class |
|---|---|---|
| 4-octylphenol | A member of the class of phenols that is phenol which is substituted at the para- position by an octyl group. | 4-octylphenol |
| cetrimonium bromide | The organic bromide salt that is the bromide salt of cetyltrimethylammonium; one of the components of the topical antiseptic cetrimide. | cetyltrimethylammonium bromide |
| cetylpyridinium chloride anhydrous | A pyridinium salt that has N-hexadecylpyridinium as the cation and chloride as the anion. It has antiseptic properties and is used in solutions or lozenges for the treatment of minor infections of the mouth and throat. | cetylpyridinium chloride |
| cocamidopropyl betaine | An ammonium betaine in which the the ammonium nitrogen is substituted by two methyl groups and a lauramidopropyl group. It is the major (>50%) component of cocamidopropyl betaine. | lauramidopropyl betaine |
| colfosceril palmitate | A phosphatidylcholine 32:0 in which the 1- and 2-acyl groups are specified as hexadecanoyl (palmitoyl). A synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. It is also a major constituent of pulmonary surfactants. | 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine |
| diisopropanolamine | A secondary amino compound that is diethanolamine substituted by methyl groups at positions 1 and 1'. It is a versatile chemical used in a variety of personal care, cosmetic and industrial products. | diisopropanolamine |
| dimethyldodecylbenzylammonium | The organic bromide salt of benzododecinium. It is a cationic surfactant that has antispetic and disinfectant properties. | benzododecinium bromide |
| dodecyltrimethylammonium bromide | A quarternary ammonium cation having one dodecyl and three methyl substituents around the central nitrogen. | dodecyltrimethylammonium bromide |
| perfluoro-n-nonanoic acid | A fluoroalkanoic acid that is nonanoic acid in which all of the hydrogens in the alkyl chain are replaced by fluorines. | perfluorononanoic acid |
| perfluorobutane sulfonate | A perfluoroalkanesulfonic acid that is butane-1-sulfonic acid in which all of the hydrogens of the butyl group have been replaced by fluorines. | perfluorobutanesulfonic acid |
| perfluorooctanoic acid | A fluoroalkanoic acid that is perfluorinated octanoic acid. | perfluorooctanoic acid |
| sterogenol | A pyridinium salt that has N-hexadecylpyridinium as the cation and bromide as the anion. | cetylpyridinium bromide |
| surfactin A | A cyclodepsipeptide that is N-[(3R)-3-hydroxy-11-methyldodecanoyl]-L-alpha-glutamyl-L-leucyl-D-leucyl-L-valyl-L-alpha-aspartyl-D-leucyl-L-leucine in which the C-terminal carboxy group has been lactonised by condensation with the alcoholic hydroxy group. | surfactin A |
| surfactin c | A cyclodepsipeptide that is N-[(3R)-3-hydroxy-13-methyltetradecanoyl]-L-alpha-glutamyl-L-leucyl-D-leucyl-L-valyl-L-alpha-aspartyl-D-leucyl-L-leucine in which the C-terminal carboxy group has been lactonised by condensation with the alcoholic hydroxy group. | surfactin C |
| triethanolamine | A tertiary amino compound that is ammonia in which each of the hydrogens is substituted by a 2-hydroxyethyl group. | triethanolamine |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 11,400 (44.92) | 18.7374 |
| 1990's | 4,149 (16.35) | 18.2507 |
| 2000's | 2,934 (11.56) | 29.6817 |
| 2010's | 5,560 (21.91) | 24.3611 |
| 2020's | 1,334 (5.26) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 614 (2.18%) | 5.53% |
| Reviews | 2,427 (8.61%) | 6.00% |
| Case Studies | 200 (0.71%) | 4.05% |
| Observational | 19 (0.07%) | 0.25% |
| Other | 24,923 (88.43%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 10.3840 | 2 | 4 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 48.1379 | 3 | 23 |
| acid sphingomyelinase | Homo sapiens (human) | Potency | 56.2341 | 1 | 1 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 50.0543 | 2 | 9 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 20.9358 | 11 | 75 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 34.3523 | 2 | 4 |
| Ataxin-2 | Homo sapiens (human) | Potency | 7.3669 | 1 | 7 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 7.9963 | 2 | 12 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 55.4555 | 1 | 5 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 54.8153 | 1 | 1 |
| caspase-3 | Homo sapiens (human) | Potency | 55.4555 | 1 | 5 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 54.8153 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 44.1433 | 3 | 21 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 0.3548 | 1 | 1 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 39.8107 | 1 | 1 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 40.8708 | 1 | 2 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 5.6104 | 1 | 2 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 27.4170 | 1 | 4 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 6.0909 | 1 | 5 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 23.8832 | 1 | 5 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 16.2214 | 1 | 10 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 26.2870 | 12 | 90 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 54.7243 | 3 | 19 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 18.8747 | 9 | 62 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 42.9337 | 5 | 24 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 35.4813 | 1 | 3 |
| G | Vesicular stomatitis virus | Potency | 27.4170 | 1 | 4 |
| GALC protein | Homo sapiens (human) | Potency | 0.6310 | 1 | 1 |
| geminin | Homo sapiens (human) | Potency | 12.8325 | 2 | 6 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 11.6454 | 3 | 22 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 3.5481 | 1 | 1 |
| GLS protein | Homo sapiens (human) | Potency | 31.8326 | 1 | 2 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 37.1210 | 5 | 27 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 26.3108 | 1 | 9 |
| Glycoprotein hormones alpha chain | Homo sapiens (human) | Potency | 1.0000 | 1 | 2 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 43.3126 | 2 | 15 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 52.0474 | 2 | 5 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 47.3936 | 1 | 2 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 27.4170 | 1 | 4 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 23.7358 | 1 | 2 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 39.7572 | 2 | 17 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| IDH1 | Homo sapiens (human) | Potency | 13.2780 | 1 | 2 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 27.4170 | 1 | 8 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 2.2387 | 1 | 1 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| Interferon beta | Homo sapiens (human) | Potency | 28.9012 | 2 | 7 |
| interleukin 8 | Homo sapiens (human) | Potency | 66.8242 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 3.0929 | 1 | 2 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 31.6228 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 55.7313 | 2 | 4 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 12.8117 | 2 | 3 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 34.0029 | 2 | 3 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 34.5351 | 4 | 33 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 21.1446 | 1 | 2 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 50.1187 | 1 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 48.4750 | 2 | 10 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 1.1883 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 8.4526 | 2 | 6 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 7.9433 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 47.6130 | 3 | 19 |
| P53 | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 13.9872 | 2 | 4 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 44.2100 | 5 | 23 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 44.1176 | 5 | 26 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 47.3936 | 1 | 2 |
| polyprotein | Zika virus | Potency | 35.4813 | 1 | 3 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 28.1838 | 1 | 2 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 17.0390 | 1 | 2 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 42.3679 | 1 | 7 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 50.1187 | 1 | 2 |
| progesterone receptor | Homo sapiens (human) | Potency | 51.1290 | 2 | 15 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 47.3936 | 1 | 2 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 10.0027 | 2 | 17 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 70.7946 | 1 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 28.8914 | 3 | 31 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 20.3175 | 4 | 24 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 37.6858 | 1 | 1 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 25.1117 | 2 | 16 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 25.1117 | 2 | 16 |
| Smad3 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 19.0328 | 1 | 3 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 15.9433 | 1 | 4 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 5.5304 | 2 | 16 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 12.0419 | 3 | 21 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 55.0828 | 4 | 8 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 21.4640 | 4 | 9 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 33.7478 | 2 | 8 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 23.4788 | 1 | 4 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 41.2560 | 2 | 14 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 28.7657 | 4 | 22 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 68.2593 | 1 | 4 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 26.3108 | 1 | 9 |
| Vpr | Human immunodeficiency virus 1 | Potency | 39.4723 | 1 | 2 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| 10 kDa chaperonin | Escherichia coli | IC50 | 9.2500 | 2 | 2 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 7.4000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | IC50 | 2.8310 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | Ki | 1.6180 | 1 | 1 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | IC50 | 2.8310 | 1 | 1 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | Ki | 1.6180 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | IC50 | 3.1730 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | Ki | 0.9070 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | IC50 | 5.6900 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 3.6210 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 1.2880 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 0.6740 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 1.2880 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 0.6740 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli K-12 | IC50 | 210.0000 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 9.2500 | 2 | 2 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 7.4000 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 7.1120 | 1 | 2 |
| Adenosine receptor A2a | Homo sapiens (human) | IC50 | 22.4320 | 1 | 1 |
| Adenosine receptor A2a | Homo sapiens (human) | Ki | 12.5930 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 5.3860 | 1 | 2 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 3.0440 | 1 | 2 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 32.1500 | 1 | 2 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | Ki | 31.8845 | 1 | 2 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 5.3860 | 1 | 2 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 3.0440 | 1 | 2 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 5.3860 | 1 | 2 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 3.0440 | 1 | 2 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 7.2650 | 1 | 2 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 2.7245 | 1 | 2 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | IC50 | 7.1370 | 1 | 2 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Ki | 3.2585 | 1 | 2 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | IC50 | 7.8655 | 1 | 2 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | Ki | 1.1425 | 1 | 2 |
| Androgen receptor | Rattus norvegicus (Norway rat) | IC50 | 19.0546 | 1 | 1 |
| cysteine protease ATG4B isoform a | Homo sapiens (human) | IC50 | 7.1400 | 1 | 1 |
| Dynamin-1 | Homo sapiens (human) | IC50 | 10.3450 | 1 | 2 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 9.8455 | 1 | 2 |
| Estrogen receptor | Homo sapiens (human) | IC50 | 27.6740 | 1 | 1 |
| Estrogen receptor | Homo sapiens (human) | Ki | 7.9070 | 1 | 1 |
| Melanocortin receptor 4 | Homo sapiens (human) | IC50 | 5.0810 | 1 | 1 |
| Melanocortin receptor 4 | Homo sapiens (human) | Ki | 4.8860 | 1 | 1 |
| Melanocortin receptor 5 | Homo sapiens (human) | IC50 | 3.7260 | 1 | 1 |
| Melanocortin receptor 5 | Homo sapiens (human) | Ki | 3.4950 | 1 | 1 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 15.0160 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | IC50 | 9.0230 | 1 | 2 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | Ki | 2.1730 | 1 | 2 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | IC50 | 6.2910 | 1 | 2 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | Ki | 2.2365 | 1 | 2 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | IC50 | 9.5190 | 1 | 2 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | Ki | 2.0176 | 1 | 2 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | IC50 | 0.1060 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | Ki | 0.0150 | 1 | 1 |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | IC50 | 15.3870 | 1 | 2 |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | Ki | 11.0546 | 1 | 2 |
| NAD-dependent protein deacetylase HST2 | Saccharomyces cerevisiae S288C | IC50 | 700.0000 | 1 | 1 |
| NAD-dependent protein deacetylase sirtuin-1 | Homo sapiens (human) | IC50 | 600.0000 | 2 | 2 |
| phospholipase A2 precursor | Homo sapiens (human) | IC50 | 8.3400 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | IC50 | 4.0930 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 10.3190 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 2.8620 | 1 | 1 |
| putative polyprotein | IC50 | 13.7115 | 2 | 2 | |
| rac GTPase-activating protein 1 isoform a | Homo sapiens (human) | IC50 | 61.0900 | 1 | 1 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | IC50 | 1.8780 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | IC50 | 7.3850 | 1 | 2 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 5.8675 | 1 | 2 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 32.1500 | 1 | 2 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 31.8845 | 1 | 2 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | IC50 | 4.3265 | 1 | 2 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | Ki | 2.2980 | 1 | 2 |
| Substance-K receptor | Homo sapiens (human) | IC50 | 13.0310 | 1 | 2 |
| Substance-K receptor | Homo sapiens (human) | Ki | 4.3435 | 1 | 2 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Thromboxane-A synthase | Homo sapiens (human) | IC50 | 36.2505 | 1 | 2 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | IC50 | 0.2980 | 1 | 1 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | IC50 | 12.6180 | 1 | 2 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Caspase-2 | Homo sapiens (human) | EC50 | 21.0000 | 1 | 1 |
| ORF73 | Human gammaherpesvirus 8 | EC50 | 75.0000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| DNA repair protein RAD52 homolog isoform a | Homo sapiens (human) | AC50 | 3.7900 | 1 | 1 |
| heat shock protein 90, putative | Plasmodium falciparum 3D7 | AC50 | 4.0320 | 1 | 1 |
| heat shock protein HSP 90-alpha isoform 2 | Homo sapiens (human) | AC50 | 4.2200 | 1 | 1 |