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polyazaalkane
Any azaalkane in which two or more carbons in the chain are replaced by nitrogen.
ChEBI ID: 39474
Members (15)
| Member | Definition | Role |
|---|---|---|
| 3,7-diazanonane-1,9-diamine | 2,3,2-tetramine | |
| caldopentamine | A polyazaalkane that is the 1,5,9,13,17-pentaaza derivative of heptodecane. | caldopentamine |
| diethylenetriamine | diethylenetriamine | |
| dipropylenetriame | bis(3-aminopropyl)amine | |
| methenamine | A polycyclic cage that is adamantane in which the carbon atoms at positions 1, 3, 5 and 7 are replaced by nitrogen atoms. | hexamethylenetetramine |
| n-(3-aminopropyl)cadaverine | A polyazaalkane that is the 1,4,11-triaza derivative of undecane. | aminopropylcadaverine |
| n,n,n',n'',n''-pentamethyldiethylenetriamine | pentamethyldiethylenetriamine | |
| n(1), n(12)-diethylspermine | A substituted spermine that is spermine in which a hydrogen attached to each of the primary amino groups has been replaced by an ethyl group. | N(1),N(12)-diethylspermine |
| norspermine | A polyazaalkane consisting of a 13-membered straight chain alkane with aza-groups at the 1-, 5-, 9- and 13-positions. | 3,3,3-tetramine |
| spermidine | A triamine that is the 1,5,10-triaza derivative of decane. | spermidine |
| spermine | A polyazaalkane that is tetradecane in which the carbons at positions 1, 5, 10 and 14 are replaced by nitrogens. Spermine has broad actions on cellular metabolism. | spermine |
| sym-homospermidine | A polyazaalkane comprising undecane with three aza groups placed at the 1-, 6- and 11-positions. | sym-homospermidine |
| tetraethylenepentamine | tetraethylenepentamine | |
| thermospermine | Propane-1,3-diamine in which a hydrogen attached to one nitrogen is substituted by a 3-aminoprop-1-yl group, and a hydrogen attached to the other nitrogen is substituted by a 4-aminobut-1-yl group. A polyamine natural product, its name arises from its similarity to spermine and the fact that it was first isolated from the extreme thermophile, Thermus thermophilus. | thermospermine |
| trientine | A polyazaalkane that is decane in which the carbon atoms at positions 1, 4, 7 and 10 are replaced by nitrogens. | 2,2,2-tetramine |
Research
Studies (10,470)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 3,799 (36.28) | 18.7374 |
| 1990's | 2,138 (20.42) | 18.2507 |
| 2000's | 1,918 (18.32) | 29.6817 |
| 2010's | 1,903 (18.18) | 24.3611 |
| 2020's | 712 (6.80) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 138 (0.98%) | 5.53% |
| Reviews | 522 (3.72%) | 6.00% |
| Case Studies | 137 (0.98%) | 4.05% |
| Observational | 4 (0.03%) | 0.25% |
| Other | 13,217 (94.29%) | 84.16% |