A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
| Member | Definition | Class |
|---|
| 7-chloro-3-methyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol | A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1, a methyl substituent at position 3, a chloro substituent at position 7 and a hydroxy substituent at position 8. | SCH 23390 |
| aj 76 | A secondary amino compound that consists of tetralin bearing methyl, propylamino and methoxy groups at positions 1, 2 and 5 respectively. Dopamine receptor antagonist with preferential action at presynaptic receptors (pKi values are 6.95, 6.67, 6.37, 6.21 and 6.07 at hD3. hD4, hD2S, hD2L and rD2 receptors respectively). | (1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin |
| amoxapine | A dibenzooxazepine compound having a chloro substituent at the 2-position and a piperazin-1-yl group at the 11-position. | amoxapine |
| azaperone | An N-arylpiperazine that is 2-(piperazin-1-yl)pyridine in which the amino hydrogen is replaced by a 3-(4-fluobenzoyl)propyl group. Used mainly as a tranquiliser for pigs and elephants. | azaperone |
| butaclamol | An organic heteropentacyclic compound that is 2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[1,2,3-de]pyrido[2,1-a]isoquinoline substituted at position 3 by both hydroxy and tert-butyl groups. | (+)-butaclamol |
| chlorpromazine | A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety. | chlorpromazine |
| clopenthixol | A thioxanthene derivative having a chloro substituent at the 2-position and an alkylidene group at the 10-position with undefined double bond stereochemistry. | clopenthixol |
| clozapine | A benzodiazepine that is 5H-dibenzo[b,e][1,4]diazepine substituted by a chloro group at position 8 and a 4-methylpiperazin-1-yl group at position 11. It is a second generation antipsychotic used in the treatment of psychiatric disorders like schizophrenia. | clozapine |
| domperidone | 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations. | domperidone |
| droperidol | An organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, and in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. | droperidol |
| fenoldopam | | fenoldopam |
| flupenthixol | A flupenthixol in which the double bond adopts a cis-configuration. | cis-flupenthixol |
| fluphenazine | A member of the class of phenothiazines that is 10H-phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position. | fluphenazine |
| fluphenazine depot | The prodrug of fluphenazine, an antipsychotic drug used for the symptomatic management of psychosis in patients with schizophrenia. | fluphenazine decanoate |
| haloperidol | A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety. | haloperidol |
| hp 873 | A member of the class of piperidines that is the 4-acetyl-2-methoxyphenyl ether of 3-(piperidin-1-yl)propan-1-ol which is substituted at position 4 of the piperidine ring by a 6-fluoro-1,2-benzoxazol-3-yl group. A member of the group of second generation antipsychotics (also known as an atypical antipsychotics), it is used for the treatment of schizophrenia. | iloperidone |
| levosulpiride | An optically active form of sulpiride having (S)-configuration. The active enantiomer of the racemic drug sulpiride. Selective D2-like dopamine antagonist (Ki values are ~ 0.015. ~ 0.013, 1, ~ 45 and ~ 77 muM at D2, D3, D4, D1 and D5 receptors respectively). | (S)-(-)-sulpiride |
| loxapine | | loxapine |
| lurasidone | An N-arylpiperazine that is (3aR,4S,7R,7aS)-2-{[(1R,2R)-2-(piperazin-1-ylmethyl)cyclohexyl]methyl}hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione in which position N4 of the piperazine ring is substituted by a 1,2-benzothiazol-3-yl group. Lurasidone is used (generally as the hydrochloride salt) as an atypical antipsychotic for the treatment of schizophrenia. | lurasidone |
| lurasidone hydrochloride | A hydrochloride obtained by reaction of lurasidone with one equivalent of hydrochloric acid. An atypical antipsychotic agent used for the treatment of schizophrenia. | lurasidone hydrochloride |
| mesoridazine | A phenothiazine substituted at position 2 (para to the S atom) by a methylsulfinyl group, and on the nitrogen by a 2-(1-methylpiperidin-2-yl)ethyl group. | mesoridazine |
| methiothepin | A dibenzothiepine that is 10,11-dihydrodibenzo[b,f]thiepine bearing additional methylthio and 4-methylpiperazin-1-yl substituents at positions 8 and 10 respectively. Potent 5-HT2 antagonist, also active as 5-HT1 antagonist. Differentiates 5-HT1D sub-types. Also displays affinity for rodent 5-HT5B, 5-HT5A, 5-HT7 and 5-HT6 receptors (pK1 values are 6.6, 7.0, 8.4 and 8.7 respectively). | methiothepin |
| methotrimeprazine | A member of the class of phenothiazines that is 10H-phenothiazine substituted by a (2R)-3-(dimethylamino)-2-methylpropyl group and a methoxy group at positions 10 and 2 respectively. | methotrimeprazine |
| metoclopramide | A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine. | metoclopramide |
| nafadotride | A naphthalenecarboxamide resulting from the formal condensation of the carboxylic acid group of 4-cyano-1-methoxynaphthalene-2-carboxylic acid with the primary amino group of 1-(1-butylpyrrolidin-2-yl]methanamine. It is a highly potent, competitive, preferential dopamine D3 receptor antagonist, centrally active upon systemic administration. | nafadotride |
| olanzapine | A benzodiazepine that is 10H-thieno[2,3-b][1,5]benzodiazepine substituted by a methyl group at position 2 and a 4-methylpiperazin-1-yl group at position 4. | olanzapine |
| perazine | A phenothiazine derivative in which 10H-phenothiazinecarries a 3-(4-methylpiperazin-1-yl)propyl substituent at the N-10 position. | perazine |
| perphenazine | A phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10. | perphenazine |
| pimozide | A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which one of the nitrogens is substituted by a piperidin-4-yl group, which in turn is substituted on the nitrogen by a 4,4-bis(p-fluorophenyl)butyl group. | pimozide |
| pipamperone | A member of the class of bipiperidines that is 1,4'-bipiperidine which is substituted at the 1' and 4' positions by 4-(p-fluorophenyl)-4-oxobutyl and carboxamide groups, respectively. A first generation antipsychotic, its properties are generally similar to those of haloperidol. | pipamperone |
| pipamperone dihydrochloride | A hydrochloride resulting from the reaction of pipamperone with 2 mol eq. of hydrogen chloride. It is used as an antipsychotic. | pipamperone dihydrochloride |
| prochlorperazine | A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position. | prochlorperazine |
| promazine | A phenothiazine deriative in which the phenothiazine tricycle has a 3-(dimethylaminopropyl) group at the N-10 position. | promazine |
| propiomazine | A member of the class of phenothiazines that is 10H-phenothiazine substituted by a 2-(dimethylamino)propyl group at nitrogen atom and a propanoyl group at position 2. | propiomazine |
| quetiapine | | quetiapine |
| risperidone | A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2. | risperidone |
| ritanserin | A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action. | ritanserin |
| serentil | The benzenesulfonate salt of mesoridazine prepared using equimolar amounts of mesoridazine and benzenesulfonic acid. | mesoridazine besylate |
| spiperone | An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively. | spiperone |
| spiramide | An azaspiro compound that consists of 1,3,8-triazaspiro[4.5]decan-4-one having a phenyl group attached to N-1 and a 3-(4-fluorophenoxy)propyl attached to N-8. Selective 5-HT antagonist, which binds to 5-HT2 sites as potently as spiperone but has lower affinity for 5-HT2C receptors. Also a high affinity D2 receptor antagonist (Ki = 3 nM). Lacks the disruptive effect of spiperone on animal behaviour. | spiramide |
| sulpiride | A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine. | sulpiride |
| tetrahydropalmatine | A berberine alkaloid obtained by formal addition of two molecules of hydrogen to the pyridine ring of palmatine. | tetrahydropalmatine |
| thiethylperazine | A member of the class of phenothiazines that is perazine substituted by a ethylsulfanyl group at position 2. | thiethylperazine |
| thiopropazate | A phenothiazine derivative in which 10H-phenothiazine has a chloro subsitituent at the 2-position and a 3-[4-(2-acetoxyethyl)piperazin-1-yl]propyl group at N-10. | thiopropazate |
| thioridazine | A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position. | thioridazine |
| trifluoperazine | A member of the class of phenothiazines that is phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position. | trifluoperazine |
| triflupromazine | A member of the class of phenothiazines that is 10H-phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-(dimethylamino)propyl group at the N-10 position. | triflupromazine |
| ziprasidone | A piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms. | ziprasidone |
| zuclopenthixol | The (Z)-isomer of clopenthixol. | zuclopenthixol |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 23.1358 | 1 | 4 |
| 67.9K protein | Vaccinia virus | Potency | 20.3233 | 2 | 19 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 27.5295 | 3 | 30 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 22.6093 | 2 | 14 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 31.0642 | 1 | 6 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 33.9972 | 2 | 2 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 4.4668 | 1 | 1 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 22.5787 | 1 | 4 |
| AR protein | Homo sapiens (human) | Potency | 23.6773 | 11 | 105 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 33.2367 | 2 | 9 |
| arylsulfatase A | Homo sapiens (human) | Potency | 15.4323 | 1 | 13 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 18.8939 | 3 | 23 |
| Ataxin-2 | Homo sapiens (human) | Potency | 19.6426 | 2 | 24 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 15.4074 | 1 | 13 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 25.4705 | 2 | 13 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 12.8408 | 1 | 4 |
| atrial natriuretic peptide receptor 2 precursor | Homo sapiens (human) | Potency | 16.9306 | 1 | 12 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 7.1142 | 2 | 10 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 38.7486 | 1 | 6 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 37.9124 | 1 | 11 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 33.0838 | 1 | 7 |
| caspase-3 | Homo sapiens (human) | Potency | 37.9124 | 1 | 11 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 33.0838 | 1 | 7 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 31.1656 | 3 | 20 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 15.3444 | 2 | 23 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 29.3111 | 1 | 6 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 27.2238 | 2 | 4 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 33.2827 | 2 | 10 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 26.8686 | 2 | 5 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 31.8885 | 2 | 5 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 52.1330 | 1 | 7 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 12.4680 | 2 | 10 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 15.8114 | 1 | 2 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 20.9127 | 1 | 16 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 31.8885 | 2 | 5 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 40.1199 | 2 | 23 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 10.1456 | 1 | 14 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 23.8283 | 1 | 5 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 29.4571 | 1 | 8 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 4.4267 | 1 | 23 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 4.7557 | 1 | 39 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 11.6793 | 2 | 50 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 15.7638 | 2 | 28 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 23.6358 | 1 | 11 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 3.7933 | 3 | 48 |
| D(1A) dopamine receptor | Sus scrofa (pig) | Potency | 20.1323 | 1 | 10 |
| D(3) dopamine receptor isoform e | Homo sapiens (human) | Potency | 0.0891 | 1 | 1 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | Potency | 14.5725 | 1 | 9 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 59.6218 | 1 | 2 |
| DNA polymerase III, partial | Bacillus subtilis | Potency | 23.8833 | 1 | 3 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 62.6177 | 1 | 8 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 25.1888 | 1 | 7 |
| dopamine D1 receptor | Homo sapiens (human) | Potency | 0.0414 | 1 | 3 |
| endonuclease IV | Escherichia coli | Potency | 13.8095 | 1 | 3 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 24.1504 | 11 | 96 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 16.9196 | 2 | 15 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 25.7042 | 9 | 97 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 18.5975 | 2 | 44 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 23.3738 | 4 | 35 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 30.4366 | 3 | 15 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 20.8803 | 2 | 5 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 28.9575 | 1 | 23 |
| G | Vesicular stomatitis virus | Potency | 29.4571 | 1 | 8 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 11.5541 | 1 | 26 |
| GALC protein | Homo sapiens (human) | Potency | 10.4836 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 11.5541 | 1 | 26 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 11.5541 | 1 | 26 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 11.5541 | 1 | 26 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 11.5541 | 1 | 26 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 11.5541 | 1 | 26 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 11.5541 | 1 | 26 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 11.5541 | 1 | 26 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 11.5541 | 1 | 26 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 11.5541 | 1 | 26 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 11.5541 | 1 | 26 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 11.5541 | 1 | 26 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 11.5541 | 1 | 26 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 11.5541 | 1 | 26 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 11.5541 | 1 | 26 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 11.5541 | 1 | 26 |
| geminin | Homo sapiens (human) | Potency | 15.8975 | 4 | 43 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 10.9437 | 2 | 35 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 14.7072 | 2 | 9 |
| GLS protein | Homo sapiens (human) | Potency | 14.3359 | 2 | 15 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 18.9642 | 1 | 13 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 21.8262 | 3 | 38 |
| glucokinase regulatory protein | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 30.0015 | 1 | 10 |
| Glycoprotein hormones alpha chain | Homo sapiens (human) | Potency | 14.1254 | 1 | 2 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 26.6514 | 2 | 2 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 32.7461 | 2 | 10 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 37.2374 | 2 | 11 |
| hexokinase-4 isoform 1 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 13.8547 | 2 | 61 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 30.2836 | 1 | 7 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 26.3869 | 2 | 3 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 59.9080 | 2 | 9 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 29.4571 | 1 | 8 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 28.4491 | 1 | 5 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 22.3872 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 23.5527 | 2 | 10 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 9.9332 | 2 | 26 |
| IDH1 | Homo sapiens (human) | Potency | 19.3106 | 1 | 10 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 29.4571 | 1 | 16 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 6.4145 | 2 | 12 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 20.0920 | 1 | 9 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 20.0920 | 1 | 9 |
| Interferon beta | Homo sapiens (human) | Potency | 24.5241 | 3 | 16 |
| isocitrate dehydrogenase 1, partial | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 15.3294 | 2 | 34 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 17.9399 | 1 | 20 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 34.2718 | 2 | 4 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 5.6234 | 1 | 1 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 28.6729 | 1 | 15 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 22.9305 | 2 | 26 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 19.7737 | 2 | 23 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 7.4530 | 2 | 31 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 0.8913 | 1 | 1 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 16.4017 | 1 | 8 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 14.4567 | 2 | 22 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 12.9105 | 1 | 4 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 67.8392 | 1 | 9 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 23.9916 | 4 | 29 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 18.3564 | 1 | 1 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 29.9575 | 2 | 11 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 27.5740 | 2 | 17 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 27.1191 | 3 | 38 |
| Ornithine decarboxylase | Rattus norvegicus (Norway rat) | Potency | 0.0063 | 1 | 2 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| Parkin | Homo sapiens (human) | Potency | 24.5192 | 1 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 23.8555 | 2 | 18 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 50.7577 | 1 | 8 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 18.9874 | 5 | 19 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 23.0323 | 5 | 22 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 52.2616 | 3 | 20 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 11.7262 | 1 | 3 |
| polyprotein | Zika virus | Potency | 28.9575 | 1 | 23 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 10.6025 | 1 | 23 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 5.6796 | 1 | 31 |
| PPM1D protein | Homo sapiens (human) | Potency | 11.7086 | 1 | 2 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 17.6704 | 3 | 24 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 50.1187 | 1 | 2 |
| progesterone receptor | Homo sapiens (human) | Potency | 27.7645 | 3 | 21 |
| pyruvate kinase PKM isoform b | Homo sapiens (human) | Potency | 0.0063 | 2 | 3 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 125.8920 | 1 | 1 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 29.2938 | 1 | 3 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 22.5807 | 2 | 31 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 69.7822 | 1 | 11 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 13.4575 | 1 | 17 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 30.6103 | 3 | 41 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 13.3318 | 4 | 29 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 19.3579 | 4 | 41 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 14.3406 | 2 | 6 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 14.3406 | 2 | 6 |
| Smad3 | Homo sapiens (human) | Potency | 25.4804 | 1 | 8 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 21.0024 | 2 | 23 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 15.7324 | 1 | 18 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 3.8893 | 1 | 3 |
| TDP1 protein | Homo sapiens (human) | Potency | 20.0948 | 2 | 111 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 60.3740 | 1 | 2 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 17.6489 | 4 | 17 |
| Thrombopoietin | Homo sapiens (human) | Potency | 14.9273 | 2 | 20 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 19.6779 | 3 | 54 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 47.9568 | 2 | 2 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 24.8427 | 5 | 43 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 8.1404 | 2 | 4 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 11.0270 | 1 | 3 |
| transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | Potency | 16.5373 | 1 | 4 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 14.5725 | 1 | 9 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 11.7262 | 1 | 3 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 11.7262 | 1 | 3 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 44.5636 | 3 | 32 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 14.1035 | 2 | 31 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 20.6914 | 4 | 22 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 61.2931 | 1 | 12 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 30.0015 | 1 | 10 |
| Vpr | Human immunodeficiency virus 1 | Potency | 12.5893 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase | Homo sapiens (human) | Ki | 0.0990 | 1 | 2 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Rattus norvegicus (Norway rat) | Ki | 0.0188 | 1 | 4 |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | IC50 | 0.8250 | 1 | 2 |
| 5-hydroxytryptamine receptor 1A | Mus musculus (house mouse) | IC50 | 0.8800 | 2 | 3 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | IC50 | 2.4776 | 7 | 19 |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | Ki | 0.7554 | 31 | 62 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | Ki | 0.7200 | 20 | 36 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | IC50 | 1.7797 | 5 | 14 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | Ki | 1.1519 | 4 | 12 |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | IC50 | 2.3512 | 3 | 4 |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | Ki | 0.0916 | 2 | 2 |
| 5-hydroxytryptamine receptor 1E | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | IC50 | 2.3512 | 3 | 4 |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | Ki | 0.0916 | 2 | 2 |
| 5-hydroxytryptamine receptor 2A | Bos taurus (cattle) | IC50 | 0.0090 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | IC50 | 0.1567 | 9 | 30 |
| 5-hydroxytryptamine receptor 2A | Mus musculus (house mouse) | IC50 | 0.0148 | 1 | 2 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | IC50 | 0.4199 | 21 | 39 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | Ki | 0.0382 | 61 | 139 |
| 5-hydroxytryptamine receptor 2A | Mus musculus (house mouse) | Ki | 0.0137 | 1 | 2 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | Ki | 0.3594 | 46 | 79 |
| 5-hydroxytryptamine receptor 2A | Sus scrofa (pig) | Ki | 0.0300 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | IC50 | 0.4000 | 2 | 20 |
| 5-hydroxytryptamine receptor 2B | Mus musculus (house mouse) | IC50 | 0.0148 | 1 | 2 |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | IC50 | 0.5291 | 15 | 28 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 0.2295 | 6 | 24 |
| 5-hydroxytryptamine receptor 2B | Mus musculus (house mouse) | Ki | 0.0137 | 1 | 2 |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | Ki | 0.9120 | 17 | 30 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 0.7965 | 8 | 27 |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | IC50 | 0.5428 | 17 | 31 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 0.7256 | 38 | 98 |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | Ki | 0.9768 | 26 | 40 |
| 5-hydroxytryptamine receptor 2C | Mus musculus (house mouse) | IC50 | 0.0148 | 1 | 2 |
| 5-hydroxytryptamine receptor 2C | Mus musculus (house mouse) | Ki | 0.0137 | 1 | 2 |
| 5-hydroxytryptamine receptor 3A | Cavia porcellus (domestic guinea pig) | IC50 | 110.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | IC50 | 0.6200 | 2 | 3 |
| 5-hydroxytryptamine receptor 3A | Homo sapiens (human) | Ki | 0.3204 | 3 | 5 |
| 5-hydroxytryptamine receptor 3A | Mus musculus (house mouse) | Ki | 2.6080 | 2 | 4 |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | Ki | 0.3813 | 8 | 9 |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | IC50 | 0.6200 | 2 | 3 |
| 5-hydroxytryptamine receptor 3B | Homo sapiens (human) | Ki | 0.3539 | 2 | 4 |
| 5-hydroxytryptamine receptor 3B | Mus musculus (house mouse) | Ki | 0.2000 | 1 | 2 |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | Ki | 0.3813 | 8 | 9 |
| 5-hydroxytryptamine receptor 3C | Homo sapiens (human) | Ki | 0.3539 | 2 | 4 |
| 5-hydroxytryptamine receptor 3D | Homo sapiens (human) | Ki | 0.3539 | 2 | 4 |
| 5-hydroxytryptamine receptor 3E | Homo sapiens (human) | Ki | 0.3539 | 2 | 4 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 0.6702 | 2 | 17 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 0.4702 | 3 | 18 |
| 5-hydroxytryptamine receptor 4 | Homo sapiens (human) | Ki | 0.1122 | 1 | 2 |
| 5-hydroxytryptamine receptor 4 | Rattus norvegicus (Norway rat) | IC50 | 35.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Rattus norvegicus (Norway rat) | Ki | 0.0800 | 1 | 1 |
| 5-hydroxytryptamine receptor 5A | Homo sapiens (human) | Ki | 10.6889 | 4 | 6 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | IC50 | 0.0643 | 9 | 16 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | Ki | 0.3358 | 43 | 84 |
| 5-hydroxytryptamine receptor 6 | Rattus norvegicus (Norway rat) | Ki | 0.0679 | 3 | 3 |
| 5-hydroxytryptamine receptor 7 | Cavia porcellus (domestic guinea pig) | IC50 | 77.4375 | 1 | 16 |
| 5-hydroxytryptamine receptor 7 | Homo sapiens (human) | IC50 | 0.0089 | 6 | 6 |
| 5-hydroxytryptamine receptor 7 | Homo sapiens (human) | Ki | 0.2472 | 50 | 83 |
| 5-hydroxytryptamine receptor 7 | Mus musculus (house mouse) | Ki | 0.0630 | 1 | 1 |
| 5-hydroxytryptamine receptor 7 | Rattus norvegicus (Norway rat) | Ki | 0.0317 | 5 | 15 |
| 6-phosphogluconate dehydrogenase, decarboxylating | Homo sapiens (human) | Ki | 2,111.3000 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | Ki | 0.2520 | 1 | 3 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 11.9350 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 6.7460 | 1 | 1 |
| Adenylate cyclase type 1 | Rattus norvegicus (Norway rat) | IC50 | 1.2467 | 2 | 3 |
| Adenylate cyclase type 1 | Rattus norvegicus (Norway rat) | Ki | 0.1180 | 1 | 1 |
| Adenylate cyclase type 2 | Rattus norvegicus (Norway rat) | IC50 | 1.2467 | 2 | 3 |
| Adenylate cyclase type 2 | Rattus norvegicus (Norway rat) | Ki | 0.1180 | 1 | 1 |
| Adenylate cyclase type 3 | Rattus norvegicus (Norway rat) | IC50 | 1.2467 | 2 | 3 |
| Adenylate cyclase type 3 | Rattus norvegicus (Norway rat) | Ki | 0.1180 | 1 | 1 |
| Adenylate cyclase type 4 | Rattus norvegicus (Norway rat) | IC50 | 1.2467 | 2 | 3 |
| Adenylate cyclase type 4 | Rattus norvegicus (Norway rat) | Ki | 0.1180 | 1 | 1 |
| Adenylate cyclase type 5 | Rattus norvegicus (Norway rat) | IC50 | 1.0725 | 3 | 4 |
| Adenylate cyclase type 5 | Rattus norvegicus (Norway rat) | Ki | 0.1180 | 1 | 1 |
| Adenylate cyclase type 6 | Rattus norvegicus (Norway rat) | IC50 | 1.2467 | 2 | 3 |
| Adenylate cyclase type 6 | Rattus norvegicus (Norway rat) | Ki | 0.1180 | 1 | 1 |
| Adenylate cyclase type 8 | Rattus norvegicus (Norway rat) | IC50 | 1.2467 | 2 | 3 |
| Adenylate cyclase type 8 | Rattus norvegicus (Norway rat) | Ki | 0.1180 | 1 | 1 |
| Adenylyl cyclase 7 | Rattus norvegicus (Norway rat) | IC50 | 1.2467 | 2 | 3 |
| Adenylyl cyclase 7 | Rattus norvegicus (Norway rat) | Ki | 0.1180 | 1 | 1 |
| Albumin | Homo sapiens (human) | IC50 | 3.5000 | 1 | 2 |
| Aldehyde oxidase | Homo sapiens (human) | IC50 | 0.3015 | 1 | 2 |
| Aldehyde oxidase | Homo sapiens (human) | Ki | 2.3000 | 1 | 1 |
| Aldehyde oxidase 1 | Macaca fascicularis (crab-eating macaque) | IC50 | 3.6000 | 1 | 1 |
| Aldehyde oxidase 1 | Mus musculus (house mouse) | IC50 | 6.1000 | 1 | 1 |
| Aldehyde oxidase 1 | Oryctolagus cuniculus (rabbit) | IC50 | 20.0000 | 1 | 1 |
| Aldehyde oxidase 1 | Rattus norvegicus (Norway rat) | IC50 | 0.7400 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 1.0976 | 1 | 9 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | Ki | 1.0884 | 1 | 9 |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | IC50 | 0.0106 | 6 | 6 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 2.0851 | 17 | 26 |
| Alpha-1A adrenergic receptor | Bos taurus (cattle) | Ki | 0.0135 | 1 | 1 |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | Ki | 0.0168 | 11 | 27 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.6373 | 22 | 49 |
| Alpha-1B adrenergic receptor | Homo sapiens (human) | IC50 | 0.0110 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 2.2549 | 15 | 24 |
| Alpha-1B adrenergic receptor | Homo sapiens (human) | Ki | 0.0152 | 10 | 24 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.6944 | 21 | 45 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | IC50 | 0.1337 | 2 | 14 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 1.8341 | 14 | 23 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | Ki | 0.0353 | 10 | 36 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.5814 | 19 | 42 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 1.4047 | 1 | 15 |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 2.3601 | 4 | 7 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 0.5128 | 6 | 31 |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.7643 | 7 | 14 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | IC50 | 0.4069 | 1 | 13 |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 2.7534 | 3 | 6 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Ki | 0.4156 | 3 | 24 |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.9597 | 5 | 11 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | IC50 | 0.7536 | 1 | 13 |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 2.7534 | 3 | 6 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | Ki | 0.3359 | 4 | 27 |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.9597 | 5 | 11 |
| Androgen receptor | Rattus norvegicus (Norway rat) | Ki | 0.8000 | 1 | 1 |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | IC50 | 12.5083 | 2 | 12 |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | Ki | 3.0615 | 2 | 11 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | IC50 | 11.5200 | 1 | 4 |
| AP-2 complex subunit sigma | Rattus norvegicus (Norway rat) | Ki | 0.0242 | 1 | 1 |
| Aspartate aminotransferase, cytoplasmic | Homo sapiens (human) | IC50 | 5.3900 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 12 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 5.8900 | 7 | 10 |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | IC50 | 27.4500 | 4 | 4 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | Ki | 7.0400 | 2 | 5 |
| bcl-2-related protein A1 | Mus musculus (house mouse) | IC50 | 20.0000 | 1 | 1 |
| Beta-1 adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 17.0000 | 3 | 4 |
| Beta-1 adrenergic receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.1500 | 1 | 1 |
| Beta-2 adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 1.2200 | 1 | 2 |
| Beta-2 adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 2 | 2 |
| Beta-3 adrenergic receptor | Homo sapiens (human) | IC50 | 29.4880 | 1 | 1 |
| Beta-3 adrenergic receptor | Homo sapiens (human) | Ki | 22.1160 | 1 | 1 |
| Beta-3 adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 2 | 2 |
| Beta-carbonic anhydrase 1 | Mycobacterium tuberculosis H37Rv | Ki | 2.3000 | 1 | 1 |
| Beta-casein | Rattus norvegicus (Norway rat) | Ki | 0.0015 | 1 | 1 |
| Beta-glucuronidase | Rattus norvegicus (Norway rat) | IC50 | 7.8000 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 135.8253 | 7 | 43 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 439.6000 | 1 | 3 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 6.6000 | 1 | 1 |
| C-8 sterol isomerase | Saccharomyces cerevisiae S288C | Ki | 0.2502 | 1 | 2 |
| Calcitonin gene-related peptide type 1 receptor | Homo sapiens (human) | Ki | 0.0262 | 1 | 2 |
| Calcium-dependent protein kinase 4 | Plasmodium falciparum 3D7 | Ki | 150.0000 | 1 | 1 |
| Calmodulin | Bos taurus (cattle) | IC50 | 2.5000 | 1 | 2 |
| Calmodulin-1 | Homo sapiens (human) | IC50 | 37.1120 | 4 | 5 |
| Calmodulin-1 | Homo sapiens (human) | Ki | 19.2800 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 12 |
| Carbonic anhydrase | Candida albicans SC5314 | Ki | 0.7600 | 2 | 2 |
| Carbonic anhydrase | Helicobacter pylori 26695 | Ki | 0.1915 | 2 | 2 |
| Carbonic anhydrase | Saccharomyces cerevisiae S288C | Ki | 0.1240 | 1 | 1 |
| Carbonic anhydrase | Stylophora pistillata | Ki | 0.4150 | 1 | 1 |
| Carbonic anhydrase | Anopheles gambiae (African malaria mosquito) | Ki | 0.0295 | 1 | 1 |
| Carbonic anhydrase | Astrosclera willeyana | Ki | 0.3780 | 1 | 1 |
| Carbonic anhydrase | Cryptococcus neoformans var. grubii | Ki | 0.8120 | 1 | 1 |
| Carbonic anhydrase | Nakaseomyces glabratus CBS 138 | Ki | 0.1130 | 1 | 1 |
| Carbonic anhydrase | Stylophora pistillata | Ki | 0.4300 | 2 | 2 |
| Carbonic anhydrase | Sulfurihydrogenibium sp. YO3AOP1 | Ki | 0.0674 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | IC50 | 1.2000 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 4.2183 | 33 | 35 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 0.0039 | 3 | 3 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | Ki | 0.0730 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | IC50 | 0.0400 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 0.3170 | 40 | 43 |
| Carbonic anhydrase 2 | Mycobacterium tuberculosis H37Rv | Ki | 0.2660 | 1 | 1 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ki | 10.6000 | 1 | 1 |
| Carbonic anhydrase 4 | Bos taurus (cattle) | IC50 | 0.6200 | 1 | 1 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 0.1740 | 1 | 1 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 0.0180 | 1 | 1 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 2.0072 | 4 | 6 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 2.4212 | 3 | 3 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 0.0409 | 6 | 7 |
| Carbonic anhydrase, alpha family | Hydrogenovibrio crunogenus XCL-2 | Ki | 0.8730 | 1 | 1 |
| Cathepsin D | Bos taurus (cattle) | IC50 | 0.0600 | 1 | 1 |
| Cholecystokinin receptor type A | Cavia porcellus (domestic guinea pig) | Ki | 0.0550 | 1 | 2 |
| Cholinesterase | Equus caballus (horse) | IC50 | 7.4000 | 1 | 1 |
| Cocaine esterase | Homo sapiens (human) | Ki | 0.0063 | 1 | 1 |
| Cys-loop ligand-gated ion channel | Dickeya chrysanthemi | IC50 | 158.0000 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 5.6662 | 1 | 2 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 6.3778 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 20.7580 | 1 | 5 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 3.0743 | 1 | 6 |
| Cytochrome P450 2D6 | Homo sapiens (human) | Ki | 3.9800 | 2 | 2 |
| Cytochrome P450 2J2 | Homo sapiens (human) | IC50 | 20.7580 | 1 | 5 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 4.8775 | 2 | 2 |
| Cytochrome P450 3A4 | Homo sapiens (human) | Ki | 0.0770 | 1 | 8 |
| D | Bos taurus (cattle) | IC50 | 1.2662 | 4 | 9 |
| D | Mus musculus (house mouse) | IC50 | 17.8750 | 2 | 2 |
| D | Rattus norvegicus (Norway rat) | IC50 | 0.3757 | 21 | 52 |
| D | Bos taurus (cattle) | Ki | 7.0307 | 9 | 15 |
| D | Mus musculus (house mouse) | Ki | 2.5300 | 1 | 1 |
| D | Rattus norvegicus (Norway rat) | Ki | 0.2111 | 27 | 63 |
| D(1A) dopamine receptor | Homo sapiens (human) | IC50 | 0.4499 | 7 | 19 |
| D(1A) dopamine receptor | Homo sapiens (human) | Ki | 0.2479 | 22 | 57 |
| D(1A) dopamine receptor | Sus scrofa (pig) | Ki | 0.0095 | 1 | 1 |
| D(1B) dopamine receptor | Homo sapiens (human) | IC50 | 0.0140 | 3 | 4 |
| D(1B) dopamine receptor | Mus musculus (house mouse) | IC50 | 35.0000 | 1 | 1 |
| D(1B) dopamine receptor | Rattus norvegicus (Norway rat) | IC50 | 0.2518 | 13 | 37 |
| D(1B) dopamine receptor | Homo sapiens (human) | Ki | 0.2089 | 6 | 9 |
| D(1B) dopamine receptor | Rattus norvegicus (Norway rat) | Ki | 0.2426 | 4 | 10 |
| D(2) dopamine receptor | Bos taurus (cattle) | IC50 | 0.9122 | 8 | 17 |
| D(2) dopamine receptor | Canis lupus familiaris (dog) | IC50 | 0.2000 | 1 | 1 |
| D(2) dopamine receptor | Homo sapiens (human) | IC50 | 0.1101 | 34 | 58 |
| D(2) dopamine receptor | Mus musculus (house mouse) | IC50 | 7.1252 | 2 | 5 |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | IC50 | 0.2207 | 49 | 115 |
| D(2) dopamine receptor | Bos taurus (cattle) | Ki | 0.2355 | 6 | 8 |
| D(2) dopamine receptor | Chlorocebus aethiops (grivet) | Ki | 0.1294 | 2 | 4 |
| D(2) dopamine receptor | Homo sapiens (human) | Ki | 0.0944 | 181 | 292 |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | Ki | 0.0690 | 69 | 179 |
| D(3) dopamine receptor | Homo sapiens (human) | IC50 | 0.1154 | 15 | 33 |
| D(3) dopamine receptor | Mus musculus (house mouse) | IC50 | 35.0000 | 1 | 1 |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | IC50 | 0.2518 | 13 | 37 |
| D(3) dopamine receptor | Chlorocebus aethiops (grivet) | Ki | 0.2345 | 1 | 2 |
| D(3) dopamine receptor | Homo sapiens (human) | Ki | 0.1327 | 88 | 166 |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | Ki | 0.1715 | 14 | 23 |
| D(4) dopamine receptor | Homo sapiens (human) | IC50 | 0.4923 | 16 | 26 |
| D(4) dopamine receptor | Mus musculus (house mouse) | IC50 | 35.0000 | 1 | 1 |
| D(4) dopamine receptor | Rattus norvegicus (Norway rat) | IC50 | 0.2518 | 13 | 37 |
| D(4) dopamine receptor | Homo sapiens (human) | Ki | 0.2114 | 80 | 138 |
| D(4) dopamine receptor | Rattus norvegicus (Norway rat) | Ki | 0.1943 | 7 | 13 |
| Delta carbonic anhydrase | Conticribra weissflogii | Ki | 0.2590 | 1 | 1 |
| Delta-type opioid receptor | Homo sapiens (human) | IC50 | 16.2300 | 2 | 3 |
| Delta-type opioid receptor | Homo sapiens (human) | Ki | 7.9190 | 1 | 2 |
| Delta-type opioid receptor | Mus musculus (house mouse) | Ki | 0.6200 | 2 | 2 |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 5.3125 | 3 | 4 |
| Diacylglycerol kinase alpha | Homo sapiens (human) | IC50 | 12.8500 | 2 | 2 |
| Dihydrofolate reductase | Bacillus anthracis | IC50 | 102.0000 | 1 | 1 |
| DNA damage-inducible transcript 3 protein | Mus musculus (house mouse) | IC50 | 6.3400 | 1 | 1 |
| DNA-dependent protein kinase catalytic subunit | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Emopamil-binding protein-like | Homo sapiens (human) | Ki | 0.0039 | 1 | 1 |
| Endothelin receptor type B | Homo sapiens (human) | Ki | 0.0228 | 2 | 7 |
| Endothelin receptor type B | Rattus norvegicus (Norway rat) | Ki | 0.0279 | 1 | 4 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 23.9740 | 1 | 3 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 2 | 3 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 2 | 7 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gastrin/cholecystokinin type B receptor | Mus musculus (house mouse) | Ki | 0.0102 | 1 | 6 |
| Genome polyprotein | | IC50 | 0.7000 | 1 | 1 |
| Genome polyprotein | Human rhinovirus sp. | IC50 | 140.0000 | 1 | 1 |
| Genome polyprotein | Human rhinovirus sp. | Ki | 0.1000 | 1 | 1 |
| Glucose-6-phosphate 1-dehydrogenase | Homo sapiens (human) | Ki | 497.2000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | IC50 | 0.8500 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | IC50 | 1.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | IC50 | 0.8500 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | IC50 | 1.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | IC50 | 0.8500 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | IC50 | 1.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | Ki | 5.0006 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 2C | Homo sapiens (human) | IC50 | 0.8500 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | IC50 | 1.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | Homo sapiens (human) | IC50 | 0.8500 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | IC50 | 1.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Homo sapiens (human) | IC50 | 0.8500 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | IC50 | 1.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Homo sapiens (human) | IC50 | 0.8500 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | IC50 | 1.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| Glycogen phosphorylase, brain form | Homo sapiens (human) | Ki | 27.4000 | 1 | 2 |
| Glycogen phosphorylase, muscle form | Homo sapiens (human) | Ki | 27.4000 | 1 | 2 |
| Histamine H1 receptor | Cavia porcellus (domestic guinea pig) | IC50 | 0.0970 | 1 | 1 |
| Histamine H1 receptor | Homo sapiens (human) | IC50 | 0.7066 | 8 | 20 |
| Histamine H1 receptor | Rattus norvegicus (Norway rat) | IC50 | 0.5921 | 2 | 7 |
| Histamine H1 receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.0558 | 4 | 7 |
| Histamine H1 receptor | Homo sapiens (human) | Ki | 0.0873 | 14 | 47 |
| Histamine H1 receptor | Rattus norvegicus (Norway rat) | Ki | 0.7033 | 2 | 3 |
| Histamine H2 receptor | Homo sapiens (human) | IC50 | 1.9884 | 1 | 7 |
| Histamine H2 receptor | Homo sapiens (human) | Ki | 1.9551 | 1 | 7 |
| Histamine H3 receptor | Homo sapiens (human) | Ki | 0.9473 | 3 | 5 |
| Histamine H4 receptor | Homo sapiens (human) | Ki | 2.3059 | 4 | 7 |
| Integrin alpha-4 | Homo sapiens (human) | Ki | 0.0039 | 1 | 1 |
| Integrin beta-1 | Homo sapiens (human) | Ki | 0.0039 | 1 | 1 |
| Kappa-type opioid receptor | Homo sapiens (human) | IC50 | 9.2566 | 2 | 5 |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.0026 | 1 | 1 |
| Kappa-type opioid receptor | Homo sapiens (human) | Ki | 4.5295 | 1 | 4 |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 7.0700 | 2 | 3 |
| Lactoperoxidase | Bos taurus (cattle) | IC50 | 5.0000 | 1 | 1 |
| Lysine-specific demethylase 4E | Homo sapiens (human) | Ki | 1.9200 | 1 | 1 |
| Lysozyme C-1 | Rattus norvegicus (Norway rat) | IC50 | 9.0000 | 1 | 1 |
| Mcl-1 | Homo sapiens (human) | IC50 | 3.7733 | 1 | 1 |
| Melanocortin receptor 3 | Homo sapiens (human) | IC50 | 24.3430 | 1 | 1 |
| Melanocortin receptor 3 | Homo sapiens (human) | Ki | 21.2440 | 1 | 1 |
| Melanocortin receptor 4 | Homo sapiens (human) | IC50 | 15.2040 | 1 | 1 |
| Melanocortin receptor 4 | Homo sapiens (human) | Ki | 14.6190 | 1 | 1 |
| Melanocortin receptor 5 | Homo sapiens (human) | IC50 | 8.5675 | 1 | 2 |
| Melanocortin receptor 5 | Homo sapiens (human) | Ki | 8.0370 | 1 | 2 |
| Mu-type opioid receptor | Homo sapiens (human) | IC50 | 8.4350 | 2 | 5 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.0400 | 1 | 1 |
| Mu-type opioid receptor | Homo sapiens (human) | Ki | 4.9065 | 3 | 6 |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 5.6025 | 3 | 4 |
| Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | Homo sapiens (human) | IC50 | 3.7650 | 2 | 2 |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | IC50 | 167.9667 | 1 | 3 |
| Multidrug and toxin extrusion protein 2 | Homo sapiens (human) | IC50 | 268.6000 | 1 | 3 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 12 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | IC50 | 1.8930 | 3 | 13 |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | IC50 | 0.7109 | 6 | 12 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | Ki | 3.0093 | 8 | 33 |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Ki | 7.8041 | 6 | 10 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | IC50 | 2.3605 | 1 | 8 |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | IC50 | 1.0409 | 6 | 8 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | Ki | 4.8291 | 3 | 16 |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | Ki | 8.1202 | 7 | 10 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | IC50 | 11.9205 | 3 | 10 |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | IC50 | 1.0327 | 7 | 10 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | Ki | 4.5314 | 3 | 16 |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | Ki | 12.0497 | 3 | 6 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | IC50 | 1.2724 | 1 | 10 |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | IC50 | 1.0409 | 6 | 8 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | Ki | 3.3016 | 4 | 22 |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | Ki | 12.0497 | 3 | 6 |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | IC50 | 1.0416 | 1 | 10 |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | IC50 | 1.0409 | 6 | 8 |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | Ki | 4.3352 | 3 | 18 |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | Ki | 12.0497 | 3 | 6 |
| Muscarinic receptor M1 | Bos taurus (cattle) | IC50 | 1.0000 | 1 | 1 |
| Myeloperoxidase | Homo sapiens (human) | IC50 | 4.3433 | 2 | 3 |
| N-acetyltransferase Eis | Mycobacterium tuberculosis H37Rv | IC50 | 6.2950 | 1 | 2 |
| N-acetyltransferase Eis | Mycobacterium tuberculosis H37Rv | Ki | 0.3900 | 1 | 1 |
| NADPH oxidase 1 | Homo sapiens (human) | IC50 | 17.0000 | 1 | 4 |
| neutrophil cytosol factor 1 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | IC50 | 14.1100 | 1 | 10 |
| Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | Ki | 3.7413 | 1 | 9 |
| Pleiotropic ABC efflux transporter of multiple drugs | Saccharomyces cerevisiae S288C | IC50 | 4.0100 | 1 | 10 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | IC50 | 9.3595 | 1 | 2 |
| Potassium channel subfamily K member 2 | Homo sapiens (human) | IC50 | 6.1167 | 1 | 6 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 1.5949 | 37 | 127 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | Ki | 7.4637 | 6 | 20 |
| Procathepsin L | Homo sapiens (human) | IC50 | 11.5200 | 1 | 4 |
| Protease | Human immunodeficiency virus 1 | IC50 | 125.0000 | 1 | 1 |
| Protease | Human immunodeficiency virus 1 | Ki | 50.0500 | 2 | 2 |
| Protein kinase C alpha type | Rattus norvegicus (Norway rat) | IC50 | 500.0000 | 1 | 1 |
| Protein kinase C beta type | Rattus norvegicus (Norway rat) | IC50 | 500.0000 | 1 | 1 |
| Protein kinase C delta type | Rattus norvegicus (Norway rat) | IC50 | 500.0000 | 1 | 1 |
| Protein kinase C epsilon type | Rattus norvegicus (Norway rat) | IC50 | 500.0000 | 1 | 1 |
| Protein kinase C eta type | Rattus norvegicus (Norway rat) | IC50 | 500.0000 | 1 | 1 |
| Protein kinase C gamma type | Rattus norvegicus (Norway rat) | IC50 | 500.0000 | 1 | 1 |
| Protein kinase C theta type | Rattus norvegicus (Norway rat) | IC50 | 500.0000 | 1 | 1 |
| Protein kinase C zeta type | Rattus norvegicus (Norway rat) | IC50 | 500.0000 | 1 | 1 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | IC50 | 19.4680 | 1 | 2 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | IC50 | 11.5200 | 1 | 4 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | IC50 | 11.5200 | 1 | 4 |
| Replicase polyprotein 1ab | Human coronavirus 229E | IC50 | 11.5200 | 1 | 4 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 10.5540 | 2 | 5 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 11.5200 | 1 | 4 |
| Retinal dehydrogenase 1 | Homo sapiens (human) | IC50 | 0.5242 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Oryctolagus cuniculus (rabbit) | IC50 | 27.6667 | 1 | 3 |
| Sigma intracellular receptor 2 | Homo sapiens (human) | Ki | 0.0590 | 7 | 8 |
| Sigma intracellular receptor 2 | Rattus norvegicus (Norway rat) | Ki | 0.0721 | 11 | 11 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | IC50 | 0.2951 | 7 | 17 |
| Sigma non-opioid intracellular receptor 1 | Rattus norvegicus (Norway rat) | IC50 | 0.2509 | 5 | 7 |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | Ki | 0.0049 | 37 | 37 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | Ki | 0.2159 | 38 | 51 |
| Sigma non-opioid intracellular receptor 1 | Rattus norvegicus (Norway rat) | Ki | 0.0148 | 7 | 7 |
| Sodium channel protein type 1 subunit alpha | Homo sapiens (human) | IC50 | 3.7847 | 3 | 3 |
| Sodium channel protein type 10 subunit alpha | Homo sapiens (human) | IC50 | 3.7847 | 3 | 3 |
| Sodium channel protein type 11 subunit alpha | Homo sapiens (human) | IC50 | 3.7847 | 3 | 3 |
| Sodium channel protein type 2 subunit alpha | Homo sapiens (human) | IC50 | 3.7847 | 3 | 3 |
| Sodium channel protein type 2 subunit alpha | Rattus norvegicus (Norway rat) | IC50 | 0.3400 | 1 | 1 |
| Sodium channel protein type 3 subunit alpha | Homo sapiens (human) | IC50 | 3.7847 | 3 | 3 |
| Sodium channel protein type 4 subunit alpha | Homo sapiens (human) | IC50 | 3.7847 | 3 | 3 |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | IC50 | 22.0140 | 6 | 6 |
| Sodium channel protein type 7 subunit alpha | Homo sapiens (human) | IC50 | 3.7847 | 3 | 3 |
| Sodium channel protein type 8 subunit alpha | Homo sapiens (human) | IC50 | 3.7847 | 3 | 3 |
| Sodium channel protein type 9 subunit alpha | Homo sapiens (human) | IC50 | 3.7847 | 3 | 3 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | IC50 | 1.8551 | 1 | 8 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | Ki | 0.5352 | 8 | 17 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | IC50 | 2.2018 | 1 | 4 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 0.8808 | 4 | 8 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 1.0976 | 1 | 9 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 1.3909 | 3 | 11 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | IC50 | 1.0646 | 2 | 11 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | Ki | 2.5397 | 4 | 19 |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | Ki | 0.0254 | 3 | 3 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | IC50 | 69.3111 | 2 | 9 |
| Solute carrier family 22 member 2 | Homo sapiens (human) | IC50 | 17.7000 | 1 | 3 |
| Sphingomyelin phosphodiesterase | Homo sapiens (human) | IC50 | 11.0000 | 1 | 1 |
| sphingosine 1-phosphate receptor 3 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Spike glycoprotein | Betacoronavirus England 1 | IC50 | 11.5200 | 1 | 4 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | IC50 | 11.5200 | 1 | 4 |
| Substance-K receptor | Homo sapiens (human) | IC50 | 24.8395 | 1 | 2 |
| Substance-K receptor | Homo sapiens (human) | Ki | 8.2800 | 1 | 2 |
| Sulfotransferase 1A1 | Homo sapiens (human) | Ki | 80.0000 | 1 | 2 |
| Sulfotransferase 2A1 | Homo sapiens (human) | Ki | 80.0000 | 1 | 2 |
| Tissue factor | Homo sapiens (human) | IC50 | 0.0228 | 1 | 1 |
| Transient receptor potential cation channel subfamily V member 1 | Rattus norvegicus (Norway rat) | Ki | 0.6083 | 3 | 3 |
| Transient receptor potential cation channel subfamily V member 2 | Rattus norvegicus (Norway rat) | Ki | 0.0050 | 1 | 1 |
| Transient receptor potential cation channel subfamily V member 4 | Rattus norvegicus (Norway rat) | Ki | 0.0050 | 1 | 1 |
| Transmembrane protease serine 2 | Homo sapiens (human) | IC50 | 11.5200 | 1 | 4 |
| Transporter | Rattus norvegicus (Norway rat) | Ki | 4.8586 | 2 | 9 |
| Trypanothione reductase | Trypanosoma cruzi | IC50 | 67.4833 | 2 | 6 |
| Trypanothione reductase | Trypanosoma cruzi | Ki | 22.6143 | 3 | 7 |
| Tryptophan 5-hydroxylase 1 | Rattus norvegicus (Norway rat) | IC50 | 0.0600 | 1 | 1 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | IC50 | 6.8510 | 1 | 4 |
| Ubiquitin carboxyl-terminal hydrolase 1 | Homo sapiens (human) | IC50 | 4.7500 | 2 | 4 |
| ubiquitin-conjugating enzyme E2 N | Homo sapiens (human) | IC50 | 16.5267 | 2 | 3 |
| UDP-glucuronosyltransferase 1A9 | Homo sapiens (human) | Ki | 344.0000 | 1 | 1 |
| UDP-glucuronosyltransferase 2B7 | Homo sapiens (human) | Ki | 590.0000 | 1 | 1 |
| Vesicular acetylcholine transporter | Rattus norvegicus (Norway rat) | Ki | 0.7120 | 2 | 2 |
| Vitamin D-binding protein | Rattus norvegicus (Norway rat) | Ki | 0.0037 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Cavia porcellus (domestic guinea pig) | IC50 | 1.4150 | 2 | 4 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | IC50 | 16.5475 | 11 | 11 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | IC50 | 6.1891 | 9 | 9 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | IC50 | 6.1891 | 9 | 9 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | IC50 | 6.1891 | 9 | 9 |
| Voltage-dependent N-type calcium channel subunit alpha-1B | Homo sapiens (human) | IC50 | 27.0000 | 1 | 1 |
| WD repeat-containing protein 48 | Homo sapiens (human) | IC50 | 5.6667 | 1 | 3 |
| XBP1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Zinc finger protein 664 | Cavia porcellus (domestic guinea pig) | Ki | 0.0066 | 1 | 1 |