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formamides

Amides with the general formula R(1)R(2)NCHO (R(1) and R(2) can be H).

ChEBI ID: 24079

Members (17)

MemberDefinitionRole
4-formylaminoantipyrineA pyrazolone that is 1,2-dihydro-3H-pyrazol-3-one substituted by a formaylamino group at position 4, methyl groups at positions 1 and 5 and a phenyl group at position 2. It is a metabolite of aminophenazone.4-formylaminoantipyrine
antimycin aA nine-membered bis-lactone having methyl substituents at the 2- and 6-positions, an n-hexyl substituent at the 8-position, an acyloxy substituent at the 7-position and an aroylamido substituent at the 3-position. It is produced by Streptomyces bacteria and has found commercial use as a fish poison.antimycin A
benphothiamineA thioester that is a synthetic analogue of thiamine obtained by acylative cleavage of the thiazole ring and O-phospohorylation.benfotiamine
coelichelinA tetrapeptide hydroxamate siderophore that is isolated from Streptomyces coelicolor.coelichelin
dimethylformamideA member of the class of formamides that is formamide in which the amino hydrogens are replaced by methyl groups.N,N-dimethylformamide
formamideThe simplest monocarboxylic acid amide, obtained by formal condensation of formic acid with ammonia. The parent of the class of formaldehydes.formamide; formimidic acid
formoterol fumarateA phenylethanoloamine having 4-hydroxy and 3-formamido substituents on the phenyl ring and an N-(4-methoxyphenyl)propan-2-yl substituent.N-[2-hydroxy-5-(1-hydroxy-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethyl)phenyl]formamide
iejimalide bA macrolide that is isolated from the marine tunicate Eudistoma cf. rigida and exhibits potent in vitro cytotoxic activity.lejimalide B
methylformamideA member of the class of formamides having a N-methyl substituent.N-methylformamide
n-benzylformamideN-benzylformamide
n-cyclohexylformamideA member of the class of formamides that is cyclohexane substituted by a formamido group.N-cyclohexylformamide
n-phenylformamideA member of the class of formamides that is formamide in which one of the amino hydrogens is replaced by a phenyl group.formanilide
orlistatA carboxylic ester resulting from the formal condensation of the carboxy group of N-formyl-L-leucine with the hydroxy group of (3S,4S)-3-hexyl-4-[(2S)-2-hydroxytridecyl]oxetan-2-one. A pancreatic lipase inhibitor, it is used as an anti-obesity drug.orlistat
respirantinA cyclodepsipeptide isolated from Streptomyces and Kitasatospora and has been shown to exhibit antimicrobial and antineoplastic activity.respirantin
thiamine disulfideThiamine disulfide
triforineA member of the class of N-alkylpiperazines in which the two amino groups of piperazine are replaced by 1-formamido-2,2,2-trichloroethyl groups. A fungicide active against a range of diseases including powdery mildew, scab and rust.triforine
vincristineA vinca alkaloid with formula C46H56N4O10 found in the Madagascar periwinkle, Catharanthus roseus. It is used (commonly as the corresponding sulfate salt)as a chemotherapy drug for the treatment of leukaemia, lymphoma, myeloma, breast cancer and head and neck cancer.vincristine

Research

Studies (4,428)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990897 (20.26)18.7374
1990's585 (13.21)18.2507
2000's1,334 (30.13)29.6817
2010's1,297 (29.29)24.3611
2020's315 (7.11)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials328 (6.82%)5.53%
Reviews419 (8.72%)6.00%
Case Studies113 (2.35%)4.05%
Observational1 (0.02%)0.25%
Other3,945 (82.08%)84.16%