Page last updated: 2024-08-05 11:09:46

secondary amine

A compound formally derived from ammonia by replacing two hydrogen atoms by hydrocarbyl groups.

ChEBI ID: 32863

Members (19)

MemberDefinitionRole
3-phenylamino-1,2-propanediolA glycol that is a derivative of glycerol in which one of the hydroxy groups is replaced by an anilino group.PAP
5-(methylamino)-3H-1,3,4-thiadiazole-2-thione5-(methylamino)-3H-1,3,4-thiadiazole-2-thione
5-methyl-n-(pyridin-3-ylmethyl)isoxazol-3-amine5-methyl-n-(pyridin-3-ylmethyl)isoxazol-3-amine
bisoprololbisoprolol
brimonidinebrimonidine
dobutamineA catecholamine that is 4-(3-aminobutyl)phenol in which one of the hydrogens attached to the nitrogen is substituted by a 2-(3,4-dihydroxyphenyl)ethyl group. A beta1-adrenergic receptor agonist that has cardiac stimulant action without evoking vasoconstriction or tachycardia, it is used as the hydrochloride to increase the contractility of the heart in the management of acute heart failure.dobutamine
methamphetamineA member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent.methamphetamine
methylanilineA methylaniline that is aniline carrying a methyl substituent at the nitrogen atom.N-methylaniline
minaprineminaprine
N-methyl-5-pyridin-4-yl-1,3,4-thiadiazol-2-amineN-methyl-5-pyridin-4-yl-1,3,4-thiadiazol-2-amine
N-methyl-6-phenyl-3-(2-pyridinyl)-1,2,4-triazin-5-amineN-methyl-6-phenyl-3-(2-pyridinyl)-1,2,4-triazin-5-amine
nortriptylineAn organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline.nortriptyline
pindololA member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.pindolol
piperidineAn azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. It is a metabolite of cadaverine, a polyamine found in the human intestine.piperidine
propranololA propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.propranolol
pyrrolesA tautomer of pyrrole that has the double bonds at positions 2 and 4.1H-pyrrole
rasagilineAn indane that consists of 1-aminoindane bearing an N-propargyl substituent. A selective, irreversible monoamine oxidase-B inhibitor.rasagiline
tln 4601diazepinomicin
zd 6474A quinazoline that is 7-[(1-methylpiperidin-4-yl)methoxy]quinazoline bearing additional methoxy and 4-bromo-2-fluorophenylamino substituents at positions 6 and 4 respectively. Used for the treatment of symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease.vandetanib

Research

Studies (80,349)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199027,888 (34.71)18.7374
1990's11,252 (14.00)18.2507
2000's15,949 (19.85)29.6817
2010's20,116 (25.04)24.3611
2020's5,144 (6.40)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials9,196 (10.66%)5.53%
Reviews5,269 (6.11%)6.00%
Case Studies4,371 (5.07%)4.05%
Observational191 (0.22%)0.25%
Other67,211 (77.94%)84.16%