Page last updated: 2024-09-28

Herpangina

Acute types of coxsackievirus infections or ECHOVIRUS INFECTIONS that usually affect children during the summer and are characterized by vesiculoulcerative lesions on the MUCOUS MEMBRANES of the THROAT; DYSPHAGIA; VOMITING, and FEVER.

Synonyms(1)

Synonym
Herpangina

Research

Studies (15)

TimeframeStudies, This Condition (%)All Conditions %
pre-19909 (60.00)23.3326
1990's1 (6.67)12.5806
2000's2 (13.33)18.1394
2010's2 (13.33)28.8240
2020's1 (6.67)9.53
DrugIndicatedRelationship StrengthStudiesTrials
lidocaine0low10
prednisolone0low10
prednisone0low10
erythromycin0low10
phenyl acetate0low10
ribavirin0medium32
metaperiodate0low20
cephalosporin c0low10
montelukast0low10
tetracycline0low10
warfarin0low10
allopurinol0low10

Protein Targets (300)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
interleukin 82002
TDP1 protein6006
AR protein5005
thyroid stimulating hormone receptor2002
estrogen receptor 2 (ER beta)2002
progesterone receptor4004
glucocorticoid receptor [Homo sapiens]5005
estrogen-related nuclear receptor alpha6006
estrogen nuclear receptor alpha6006
IDH12002
euchromatic histone-lysine N-methyltransferase 22002
Bloom syndrome protein isoform 11001
transcriptional regulator ERG isoform 31001
thyroid hormone receptor beta isoform 25005
ras-related protein Rab-9A1001
nuclear factor erythroid 2-related factor 2 isoform 13003
geminin4004
survival motor neuron protein isoform d2002
lamin isoform A-delta103003
ATP-binding cassette sub-family C member 30606
Multidrug resistance-associated protein 40606
Polyphenol oxidase 20101
Voltage-dependent calcium channel gamma-2 subunit3003
Bile salt export pump0707
Hypoxanthine-guanine phosphoribosyltransferase0001
Cellular tumor antigen p535005
Glutamate receptor 23003
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase 0101
Adenosine receptor A2a0112
Xanthine dehydrogenase/oxidase0202
Nuclear receptor ROR-gamma0101
Xanthine dehydrogenase/oxidase0214
Purine nucleoside phosphorylase0011
TAR DNA-binding protein 431001
Canalicular multispecific organic anion transporter 10606
Shiga toxin subunit A0101
Histamine H3 receptor0101
Chain A, Beta-lactamase3003
Motilin receptor0011
acid sphingomyelinase1001
GLI family zinc finger 34004
low molecular weight phosphotyrosine protein phosphatase isoform c0101
serine/threonine-protein kinase PLK11001
streptokinase A precursor0011
Motilin receptor0112
Rap guanine nucleotide exchange factor 32002
30S ribosomal protein S60213
30S ribosomal protein S70213
50S ribosomal protein L150213
Albumin0022
ATP-dependent translocase ABCB10202
ATP-dependent translocase ABCB10202
Cytochrome P450 3A40101
60 kDa chaperonin0101
50S ribosomal protein L100213
50S ribosomal protein L110213
50S ribosomal protein L7/L120213
50S ribosomal protein L190213
50S ribosomal protein L10213
50S ribosomal protein L200213
50S ribosomal protein L270213
50S ribosomal protein L280213
50S ribosomal protein L290213
50S ribosomal protein L310213
50S ribosomal protein L31 type B0213
50S ribosomal protein L320213
50S ribosomal protein L330213
50S ribosomal protein L340213
50S ribosomal protein L350213
50S ribosomal protein L360213
30S ribosomal protein S100213
30S ribosomal protein S110213
30S ribosomal protein S120213
30S ribosomal protein S130213
30S ribosomal protein S160213
30S ribosomal protein S180213
30S ribosomal protein S190213
30S ribosomal protein S200213
30S ribosomal protein S20213
30S ribosomal protein S30213
30S ribosomal protein S40213
30S ribosomal protein S50213
30S ribosomal protein S80213
30S ribosomal protein S90213
50S ribosomal protein L130213
50S ribosomal protein L140213
50S ribosomal protein L160213
50S ribosomal protein L230213
30S ribosomal protein S150213
50S ribosomal protein L170213
50S ribosomal protein L210213
50S ribosomal protein L300213
50S ribosomal protein L60213
30S ribosomal protein S140213
30S ribosomal protein S170213
30S ribosomal protein S10213
50S ribosomal protein L180213
60 kDa heat shock protein, mitochondrial0101
Cytochrome P450 2C9 0303
Chitinase B0101
ATP-dependent translocase ABCB10202
Low molecular weight phosphotyrosine protein phosphatase0101
Cytochrome P450 2J20202
50S ribosomal protein L20213
50S ribosomal protein L30213
50S ribosomal protein L240213
50S ribosomal protein L40213
50S ribosomal protein L220213
10 kDa heat shock protein, mitochondrial0101
50S ribosomal protein L50213
30S ribosomal protein S210213
50S ribosomal protein L250213
Potassium voltage-gated channel subfamily H member 20202
Cytochrome P450 1B10101
Thiosulfate sulfurtransferase0101
Lanosterol 14-alpha demethylase0101
50S ribosomal protein L36 20213
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Multidrug and toxin extrusion protein 10202
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE1001
thioredoxin reductase1001
RAR-related orphan receptor gamma4004
GLS protein1001
Microtubule-associated protein tau1001
aldehyde dehydrogenase 1 family, member A14004
vitamin D (1,25- dihydroxyvitamin D3) receptor2002
chromobox protein homolog 12002
mitogen-activated protein kinase 11001
flap endonuclease 11001
cytochrome P450 3A4 isoform 12002
muscarinic acetylcholine receptor M12002
Gamma-aminobutyric acid receptor subunit pi2002
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Gamma-aminobutyric acid receptor subunit beta-12002
Gamma-aminobutyric acid receptor subunit delta2002
Gamma-aminobutyric acid receptor subunit gamma-22002
Gamma-aminobutyric acid receptor subunit alpha-52002
Gamma-aminobutyric acid receptor subunit alpha-32002
Potassium voltage-gated channel subfamily A member 50101
Gamma-aminobutyric acid receptor subunit gamma-12002
Gamma-aminobutyric acid receptor subunit alpha-22002
Gamma-aminobutyric acid receptor subunit alpha-42002
Gamma-aminobutyric acid receptor subunit gamma-32002
Gamma-aminobutyric acid receptor subunit alpha-62002
Sodium channel protein type 4 subunit alpha0101
Gamma-aminobutyric acid receptor subunit alpha-12002
Gamma-aminobutyric acid receptor subunit beta-32002
Gamma-aminobutyric acid receptor subunit beta-22002
Sodium channel protein type 5 subunit alpha0101
Sodium channel protein type 9 subunit alpha0101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
GABA theta subunit2002
Gamma-aminobutyric acid receptor subunit epsilon2002
Sodium channel protein type 3 subunit alpha0101
Carbonic anhydrase 10101
Carbonic anhydrase 20101
Carbonic anhydrase 40101
Carbonic anhydrase 5A, mitochondrial0101
Carbonic anhydrase 90101
Epidermal growth factor receptor0101
Tyrosine-protein kinase Fyn0101
Beta-2 adrenergic receptor0202
Aldo-keto reductase family 1 member B10202
Alpha-2A adrenergic receptor0202
Adenosine receptor A30303
Cytochrome P450 2C80101
Muscarinic acetylcholine receptor M10202
Beta-3 adrenergic receptor0202
Alpha-1B adrenergic receptor0303
Alpha-2C adrenergic receptor0202
Muscarinic acetylcholine receptor M30202
Substance-K receptor0202
Sodium-dependent noradrenaline transporter 0202
Thromboxane-A synthase 0101
D(3) dopamine receptor0202
Delta-type opioid receptor0202
5-hydroxytryptamine receptor 2B0202
Alpha-1A adrenergic receptor0303
Sodium-dependent dopamine transporter 0202
Uracil nucleotide/cysteinyl leukotriene receptor0101
Mitogen-activated protein kinase 140101
Leukotriene C4 synthase0101
Cysteinyl leukotriene receptor 10101
Cysteinyl leukotriene receptor 20101
Cysteinyl leukotriene receptor 10213
luciferase0001
hypoxia-inducible factor 1 alpha subunit1001
cytochrome P450 family 3 subfamily A polypeptide 42002
retinoic acid nuclear receptor alpha variant 14004
pregnane X nuclear receptor4004
aryl hydrocarbon receptor1001
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a3003
v-jun sarcoma virus 17 oncogene homolog (avian)2002
nuclear receptor subfamily 1, group I, member 21001
nuclear factor erythroid 2-related factor 2 isoform 23003
Interferon beta2002
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Glucocorticoid receptor04211
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Glycine receptor subunit alpha-10404
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Androgen receptor0101
Glycine receptor subunit beta0404
Glycine receptor subunit alpha-20404
Glycine receptor subunit alpha-30404
Histamine H1 receptor0011
Prostaglandin G/H synthase 20101
Nociceptin receptor0011
Estrogen receptor beta0202
ATPase family AAA domain-containing protein 51001
Ataxin-22002
Chain A, TYROSYL-DNA PHOSPHODIESTERASE1001
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
pregnane X receptor1001
thioredoxin glutathione reductase1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)1001
nuclear receptor subfamily 1, group I, member 32002
vitamin D3 receptor isoform VDRA1001
nuclear receptor ROR-gamma isoform 11001
Nuclear receptor ROR-gamma2002
NS5 0011
Thrombopoietin1001
farnesoid X nuclear receptor1001
peroxisome proliferator activated receptor gamma3003
arylsulfatase A1001
alpha-galactosidase1001
Histone H2A.x2002
Spike glycoprotein0011
Replicase polyprotein 1ab0011
peripheral myelin protein 22 isoform 11001
glycogen synthase kinase-3 beta isoform 10011
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
Transmembrane protease serine 20011
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Polymerase basic protein 20011
RNA-directed RNA polymerase catalytic subunit0011
Polymerase acidic protein0011
Procathepsin L0011
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0011
Adenosylhomocysteinase0002
Adenosine receptor A10101
Spike glycoprotein0011
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Adenosine receptor A10101
Genome polyprotein0011
Angiotensin-converting enzyme 2 0011
90-kda heat shock protein beta HSP90 beta, partial0101
EWS/FLI fusion protein2002
estrogen receptor beta isoform 10101
heat shock protein HSP 90-alpha isoform 20101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Dihydroxyacetone phosphate acyltransferase0001
Tetracycline resistance protein, class B0001
Muscarinic acetylcholine receptor M20101
72 kDa type IV collagenase0101
Stromelysin-10101
Multidrug transporter MdfA0101
Neutrophil collagenase0101
Alpha-1D adrenergic receptor0101
Alpha-synuclein0101
Collagenase 30101
Cannabinoid receptor 10101
Integrase 0101
Solute carrier family 22 member 80001
P2Y purinoceptor 120101
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40101
Solute carrier family 22 member 70001
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
Chain A, 2-oxoglutarate Oxygenase1001
PPM1D protein1001
thyroid hormone receptor beta isoform a1001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
Albumin0011
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Protease 0101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]