Compounds of structure RSSR in which R and R' are organic groups.
| Member | Definition | Role |
|---|
| 2-hydroxyethyl disulfide | | 2,2'-dithiodiethanol |
| 2,2'-dipyridyl disulfide | A member of the class of pyridines that is pyridine which is substituted by a pyridin-2-yldisulfanediyl group at position 2. It is a reagent used in molecular biology as an oxidizing agent. Also used in peptide synthesis and for detecting thiols. | aldrithiol |
| 4,4'-dipyridyl disulfide | An organic disulfide obtained by formal oxidative dimerisation of 4-thiopyridine. | 4,4'-dipyridyl disulfide |
| allyl methyl disulfide | An organic disulfide having allyl and methyl as the two organic groups. | allyl methyl disulfide |
| bmy 25067 | An organic disulfide that is mitomycin C in which the amino group at position 7 is replaced by a {2-[(4-nitrophenyl)disulfanyl]ethyl}amino group. It is a derivative of mitomycin C with activity against a range of tumour cell lines and xenografts. | BMY-25067 |
| chetomin | An organic heteropentacyclic compound of the class of epipolythiodioxopiperazine. Isolated from Chaetomium globosum and Farrowia seminuda, it exhibits immunosuppressive activity. | chetomin |
| coenzyme a disulfide | An organic disulfide obtained via oxidative dimerisation of coenzyme A. | CoA-disulfide |
| cystamine | An organic disulfide obtgained by oxidative dimerisation of cysteamine. | cystamine |
| diallyl disulfide | An organic disulfide where the organic group specified is allyl. It has been isolated from garlic and other species of the genus Allium. | diallyl disulfide |
| dibenzothiazyl disulfide | An organic disulfide resulting from the formal oxidative coupling of the thiol groups of two molecules of 1,3-benzothiazole-2-thiol. It is used as an accelerator in the rubber industry. | dibenzothiazol-2-yl disulfide |
| dibenzyl disulfide | An organic disulfide that results from the formal oxidative dimerisation of benzyl thiol. | dibenzyl disulfide |
| dimethyl disulfide | An organic disulfide that is methane in which one of the hydrogens has been replaced by a methyldisulfanyl group. | dimethyl disulfide |
| disulfiram | An organic disulfide that results from the formal oxidative dimerisation of N,N-diethyldithiocarbamic acid. A multi-enzyme inhibitor that is used in alcohol aversion therapy and also exhibits anticancer properties. | disulfiram |
| dithionitrobenzoic acid | An organic disulfide that results from the formal oxidative dimerisation of 2-nitro-5-thiobenzoic acid. An indicator used to quantify the number or concentration of thiol groups. | dithionitrobenzoic acid |
| eptifibatide | A synthetic homodetic cyclic peptide comprising N(alpha)-(3-sulfanylpropanoyl)homoarginyl, glycyl, aspartyl, tryptophyl, prolyl and cysteinamide residues connected in sequence and cyclised via a disulfide bond. Derived from a protein found in the venom of the southeastern pygmy rattlesnake, Sistrurus miliarus barbouri, eptifibatide is an anti-coagulant that inhibits platelet aggregation by selectively blocking the platelet glycoprotein IIb/IIIa receptor, so preventing the binding of fibrinogen, von Willebrand factor, and other adhesive ligands. It is used in the management of unstable angina and in patients undergoing coronary angioplasty and stenting procedures. | eptifibatide |
| gliotoxin | A pyrazinoindole with a disulfide bridge spanning a dioxo-substituted pyrazine ring; mycotoxin produced by several species of fungi. | gliotoxin |
| glutathione disulfide | | glutathione disulfide |
| IPA-3 | An organic disulfide obtained by oxidative dimerisation of 1-sulfanylnaphthalen-2-ol. | IPA-3 |
| n-propyl disulfide | An organic disulfide where the alkyl groups specified are propyl. It is a component of the essential oils obtained from Allium. | dipropyl disulfide |
| pantethine | An organic disulfide that consists of two molecules of pantothenic acid linked by amide bonds to a cysteamine disulfide bridging group. | pantethine |
| romidepsin | A cyclodepsipeptide consisting of the cyclic disulfide of (2Z)-2-aminobut-2-enoyl, L-valyl, (3S,4E)-3-hydroxy-7-sulfanylhept-4-enoyl, D-valyl and D-cysteinyl residues coupled in sequence and cyclised head-to tail. | romidepsin |
| spiruchostatin b | A spiruchostatin with molecular formula C21H33N3O6S2 originally isolated from a Pseudomonas culture broth. | spiruchostatin B |
| sporidesmin | An organic heteropentacyclic compound that has formula C18H20ClN3O6S2, produced by the saprophyte fungus Pithomyces chartarum. It is a mycotoxin responsible for the hepatogenous photosensitisation disease facial eczema in ruminants. | sporidesmin A |
| thiamine disulfide | | Thiamine disulfide |
| thiram | An organic disulfide that results from the formal oxidative dimerisation of N,N-dimethyldithiocarbamic acid. It is widely used as a fungicidal seed treatment. | thiram |
| tropodithietic acid | A monocarboxylic acid that is 8,9-dithiabicyclo[5.2.0]nona-1,3,6-triene substituted by a carboxy group at position 2 and an oxo group at position 3. It is a broad spectrum antibiotic produced by the marine bacterium Phaeobacter inhibens that also acts as a signalling molecule at lower concentrations. | tropodithietic acid |
| trypanothione | An organic disulfide resulting from the formal oxidative coupling of the thiol groups of N(1),N(8)-bis(glutathionyl)-spermidine from the insect-parasitic trypanosomatid Crithidia fasciculata. | trypanothione disulfide |