Page last updated: 2024-08-05 14:56:06

plant growth retardant

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ChEBI ID: 35219

Members (15)

MemberDefinitionClass
2,6-diisopropylnaphthaleneA member of the class of napthalenes that is naphthalene which is substituted by an isopropyl group at positions 2 and 6. It is a plant growth regulator which inhibits the sprouting of potatoes during storage.2,6-diisopropylnaphthalene
ancymidolA tertiary alcohol that is methanol in which the hydrogens attached to the carbon are replaced by cyclopropyl, p-methoxyphenyl and pyrimidin-5-yl groups. By inhibiting gibberellin biosynthesis, ancymidol reduces plant growth, resulting in reduced internode elongation and thus more compact plants. It is used in the commercial production of a wide variety of container-grown bedding and foliage plants, including chrysanthemums, Easter lilies and poinsettias.ancymidol
carbarylA carbamate ester obtained by the formal condensation of 1-naphthol with methylcarbamic acid.carbaryl
chlormequatA quaternary ammonium ion that is choline in which the hydroxy group has been replaced by a chlorine. Its salts (particularly the chloride salt, known as chlormequat chloride) are used as plant growth retardants.chlormequat
chlorprophamA carbamate ester that is the isopropyl ester of 3-chlorophenylcarbamic acid.chlorpropham
glyphosphineA tertiary amino compound that consists of glycine bearing two N-phosphonomethyl substituents.glyphosine
levodopaAn optically active form of dopa having L-configuration. Used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinson's diseaseL-dopa zwitterion; L-dopa
mepiquatA quaternary ammonium ion has that has two methyl groups and a pentamethylene-1,5-diyl group attached to the nitrogen. Its salts are used as plant growth inhibitors.mepiquat
phenoxyacetic acidA monocarboxylic acid that is the O-phenyl derivative of glycolic acid. A metabolite of 2-phenoxyethanol, it is used in the manufacture of pharmaceuticals, pesticides, fungicides and dyes.phenoxyacetic acid
phenylacetic acidA monocarboxylic acid that is toluene in which one of the hydrogens of the methyl group has been replaced by a carboxy group.phenylacetic acid
phenylethyl alcoholA primary alcohol that is ethanol substituted by a phenyl group at position 2.2-phenylethanol
prophamA carbamate ester that is the isopropyl ester of phenylcarbamic acid. It is a selective herbicide used for the control of annual grasses and some broad-leaf weeds and is also a growth regulator for control of sprouting in stored potatoes.propham
uniconazole-pA (1E)-1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pent-1-en-3-ol that has S configuration at the chiral centre. It is the enantiomer of (R)-uniconazole; the fungicide and plant growth retardant uniconazole is the racemic mixture comprising (R)-uniconazole and uniconazole-P.uniconazole P
vibsanin bA vibsane diterpenoid that is (2Z,6E,10E)-cycloundeca-2,6,10-trien-1-one which is substituted at positions 2, 5, 5, 8, 9, and 9 by hydroxymethyl, methyl, 2-methylpent-2-en-5-yl, 3-methylbut-2-enoyloxy, hydroxy, and methyl groups, respectively (the 5S,8R,9R stereoisomer). It has been found to inhibit root growth in rice seedlings (IC50 0.14 mM).vibsanin B
xanthoxin2-cis,4-trans-xanthoxin

Research

Studies (21,936)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-19905,392 (24.58)18.7374
1990's3,579 (16.32)18.2507
2000's5,075 (23.14)29.6817
2010's5,856 (26.70)24.3611
2020's2,034 (9.27)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials1,992 (8.53%)5.53%
Reviews2,433 (10.42%)6.00%
Case Studies1,853 (7.94%)4.05%
Observational89 (0.38%)0.25%
Other16,978 (72.73%)84.16%

Protein Targets (141)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1Homo sapiens (human)Potency12.589311
15-lipoxygenase, partialHomo sapiens (human)Potency32.184113
acetylcholinesteraseHomo sapiens (human)Potency13.732048
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency25.118911
apical membrane antigen 1, AMA1Plasmodium falciparum 3D7Potency14.125411
AR proteinHomo sapiens (human)Potency25.4465924
aryl hydrocarbon receptorHomo sapiens (human)Potency33.1910312
arylsulfatase AHomo sapiens (human)Potency37.933011
Ataxin-2Homo sapiens (human)Potency60.261311
ATP-dependent phosphofructokinaseTrypanosoma brucei brucei TREU927Potency23.934111
ATPase family AAA domain-containing protein 5Homo sapiens (human)Potency61.440022
atrial natriuretic peptide receptor 1 precursorHomo sapiens (human)Potency23.934111
Bloom syndrome protein isoform 1Homo sapiens (human)Potency1.358011
bromodomain adjacent to zinc finger domain 2BHomo sapiens (human)Potency100.000011
Cellular tumor antigen p53Homo sapiens (human)Potency15.601122
Chain A, 2-oxoglutarate OxygenaseHomo sapiens (human)Potency12.589311
Chain A, ATP-DEPENDENT DNA HELICASE Q1Homo sapiens (human)Potency12.589311
Chain A, Ferritin light chainEquus caballus (horse)Potency33.552012
Chain A, HADH2 proteinHomo sapiens (human)Potency18.932724
Chain A, JmjC domain-containing histone demethylation protein 3AHomo sapiens (human)Potency39.810711
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASEHomo sapiens (human)Potency50.997612
Chain A, TYROSYL-DNA PHOSPHODIESTERASEHomo sapiens (human)Potency44.813212
Chain B, HADH2 proteinHomo sapiens (human)Potency18.932724
chromobox protein homolog 1Homo sapiens (human)Potency46.900223
cytochrome P450 2D6Homo sapiens (human)Potency20.016212
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency8.363423
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency21.144215
DNA polymerase eta isoform 1Homo sapiens (human)Potency19.595722
DNA polymerase iota isoform a (long)Homo sapiens (human)Potency12.873022
DNA polymerase kappa isoform 1Homo sapiens (human)Potency10.501514
dopamine D1 receptorHomo sapiens (human)Potency8.199511
estrogen nuclear receptor alphaHomo sapiens (human)Potency26.2753828
estrogen receptor 2 (ER beta)Homo sapiens (human)Potency23.412123
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency29.8452615
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency13.948012
EWS/FLI fusion proteinHomo sapiens (human)Potency0.372211
farnesoid X nuclear receptorHomo sapiens (human)Potency36.683933
flap endonuclease 1Homo sapiens (human)Potency23.897234
gemininHomo sapiens (human)Potency1.318623
GLI family zinc finger 3Homo sapiens (human)Potency27.483729
GLS proteinHomo sapiens (human)Potency28.362723
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency38.400822
glucokinase regulatory proteinHomo sapiens (human)Potency5.011911
Guanine nucleotide-binding protein GHomo sapiens (human)Potency22.387211
heat shock protein beta-1Homo sapiens (human)Potency60.755911
hexokinase-4 isoform 1Homo sapiens (human)Potency5.011911
histone acetyltransferase KAT2A isoform 1Homo sapiens (human)Potency31.832612
histone deacetylase 9 isoform 3Homo sapiens (human)Potency19.990528
Histone H2A.xCricetulus griseus (Chinese hamster)Potency100.101823
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)Homo sapiens (human)Potency10.000022
importin subunit beta-1 isoform 1Homo sapiens (human)Potency56.234111
Interferon betaHomo sapiens (human)Potency33.294011
LuciferasePhotinus pyralis (common eastern firefly)Potency31.752426
lysosomal alpha-glucosidase preproproteinHomo sapiens (human)Potency35.481311
M-phase phosphoprotein 8Homo sapiens (human)Potency7.519311
mitogen-activated protein kinase 1Homo sapiens (human)Potency0.001312
muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)Potency0.070811
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency28.6474414
Nuclear receptor ROR-gammaHomo sapiens (human)Potency33.491511
nuclear receptor ROR-gamma isoform 1Mus musculus (house mouse)Potency11.220211
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency33.5462327
parathyroid hormone/parathyroid hormone-related peptide receptor precursorHomo sapiens (human)Potency125.892011
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1Homo sapiens (human)Potency63.529022
peripheral myelin protein 22Rattus norvegicus (Norway rat)Potency1.622612
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency48.813622
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency0.048511
phosphoglycerate kinaseTrypanosoma brucei brucei TREU927Potency12.173933
phosphopantetheinyl transferaseBacillus subtilisPotency87.772333
pregnane X nuclear receptorHomo sapiens (human)Potency54.9601210
pregnane X receptorRattus norvegicus (Norway rat)Potency35.481311
progesterone receptorHomo sapiens (human)Potency38.079114
pyruvate kinaseLeishmania mexicana mexicanaPotency25.118922
RAR-related orphan receptor gammaMus musculus (house mouse)Potency31.4912212
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency19.1659319
retinoid X nuclear receptor alphaHomo sapiens (human)Potency36.361922
snurportin-1Homo sapiens (human)Potency56.234111
TDP1 proteinHomo sapiens (human)Potency25.278023
thioredoxin reductaseRattus norvegicus (Norway rat)Potency53.289923
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency23.588723
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency0.031611
thyroid stimulating hormone receptorHomo sapiens (human)Potency33.491511
ubiquitin carboxyl-terminal hydrolase 2 isoform aHomo sapiens (human)Potency20.749111
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency40.632825
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency1.532322
vitamin D3 receptor isoform VDRAHomo sapiens (human)Potency14.125411
WRNHomo sapiens (human)Potency5.497922

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
AcetylcholinesteraseElectrophorus electricus (electric eel)IC503.100011
AcetylcholinesteraseHomo sapiens (human)IC502,387.810011
Aldo-keto reductase family 1 member B1Homo sapiens (human)IC5096.000011
Aldo-keto reductase family 1 member B1Homo sapiens (human)Ki253.000013
ATP-binding cassette sub-family C member 3Homo sapiens (human)IC50133.000011
Bile salt export pumpHomo sapiens (human)IC50133.000011
Canalicular multispecific organic anion transporter 1Homo sapiens (human)IC50133.000011
Epidermal growth factor receptorHomo sapiens (human)IC50451.440022
Fatty-acid amide hydrolase 1Homo sapiens (human)IC5030.000022
integrase, partialHuman immunodeficiency virus 1IC500.593922
kallikrein-5 preproproteinHomo sapiens (human)IC5050.000011
Large neutral amino acids transporter small subunit 1Homo sapiens (human)IC50100.000011
lens epithelium-derived growth factor p75Homo sapiens (human)IC500.593922
Multidrug resistance-associated protein 4Homo sapiens (human)IC50133.000011
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)IC502.258011
Prolyl 4-hydroxylase subunit alpha-1Gallus gallus (chicken)Ki20,000.000011
Solute carrier family 15 member 1Homo sapiens (human)IC50141,200.000011
TyrosinaseHomo sapiens (human)IC508,400.000011
Tyrosine-protein kinase FynHomo sapiens (human)IC502.146011
Tyrosine-protein kinase LckHomo sapiens (human)IC503.729011

Activation Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
AromataseRattus norvegicus (Norway rat)EC502.000011
Olfactory receptor class A-like protein 1Danio rerio (zebrafish)EC5030.500011
Tyrosine-protein kinase LckHomo sapiens (human)Kd50,000.000011

Other Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
Abscisic acid 8'-hydroxylase 3Arabidopsis thaliana (thale cress)Kinact2.700011
Adenosine receptor A1Rattus norvegicus (Norway rat)KA11.400011
Adenosine receptor A2aRattus norvegicus (Norway rat)KA11.400012
Carbonic anhydraseCandida albicans SC5314KA0.960011
Carbonic anhydraseMethanosarcina thermophilaKA39.000011
Carbonic anhydraseMethanothermobacter thermautotrophicus str. Delta HKa11.400011
Carbonic anhydraseSaccharomyces cerevisiae S288CKa90.000022
Carbonic anhydrase Cryptococcus neoformans var. grubiiKA43.300011
Carbonic anhydrase Nakaseomyces glabratus CBS 138Ka23.300011
Carbonic anhydrase 1Homo sapiens (human)Ka3.10001111
Carbonic anhydrase 12Homo sapiens (human)KA1.670011
Carbonic anhydrase 13Mus musculus (house mouse)KA43.000011
Carbonic anhydrase 14Homo sapiens (human)KA12.100011
Carbonic anhydrase 15Mus musculus (house mouse)KA6.500011
Carbonic anhydrase 2Homo sapiens (human)Ka11.40001313
Carbonic anhydrase 3Homo sapiens (human)KA13.500022
Carbonic anhydrase 4Homo sapiens (human)Ka15.300022
Carbonic anhydrase 5A, mitochondrialHomo sapiens (human)KA0.036011
Carbonic anhydrase 5B, mitochondrialHomo sapiens (human)KA0.063011
Carbonic anhydrase 6Homo sapiens (human)Ka18.000022
Carbonic anhydrase 7Homo sapiens (human)KA58.300011
Carbonic anhydrase 9Homo sapiens (human)KA51.300011
Carbonic anhydrase-like protein, putativeTrypanosoma cruzi strain CL BrenerKA0.830011
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)KA58.300011
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)KA58.300011
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)KA58.300011
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)KA58.300011
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)KA58.300011
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)KA58.300011
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)KA58.300011
Monocarboxylate transporter 10Rattus norvegicus (Norway rat)Km6,430.000011
Plasma kallikreinHomo sapiens (human)KA0.063011
Polyphenol oxidase 2Agaricus bisporusKm860.000011
SLC16A10 proteinHomo sapiens (human)Km1,212.500011