Page last updated: 2024-08-05 12:16:58
indolizidine alkaloid
null
ChEBI ID: 38511
Members (3)
| Member | Definition | Role |
|---|---|---|
| castanospermine | A tetrahydroxyindolizidine alkaloid that consists of octahydroindolizine having four hydroxy substituents located at positions 1, 6, 7 and 8 (the 1S,6S,7R,8R,8aR-diastereomer). | castanospermine |
| lycorine | An indolizidine alkaloid that is 3,12-didehydrogalanthan substituted by hydroxy groups at positions and 2 and a methylenedioxy group across positions 9 and 10. Isolated from Crinum asiaticum, it has been shown to exhibit antimalarial activity. | lycorine |
| swainsonine | An indolizidine alkaloid isolated from the plant Swainsona canescens with three hydroxy substituents at positions 1, 2 and 8. | swainsonine |
Research
Studies (1,079)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 225 (20.85) | 18.7374 |
| 1990's | 293 (27.15) | 18.2507 |
| 2000's | 208 (19.28) | 29.6817 |
| 2010's | 264 (24.47) | 24.3611 |
| 2020's | 89 (8.25) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 10 (0.82%) | 5.53% |
| Reviews | 56 (4.61%) | 6.00% |
| Case Studies | 1 (0.08%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 1,148 (94.49%) | 84.16% |