Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter.
ChEBI ID: 37962
| Member | Definition | Class |
|---|---|---|
| aminoglutethimide | A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position. | aminoglutethimide |
| debrisoquin | debrisoquin | |
| dexmethylphenidate | A methyl phenyl(piperidin-2-yl)acetate in which both stereocentres have R configuration. It is the active enantiomer in the racemic drug methylphenidate. | dexmethylphenidate |
| dextroamphetamine | A 1-phenylpropan-2-amine that has S configuration. | (S)-amphetamine |
| fludrocortisone | fludrocortisone | |
| fluticasone propionate | A trifluorinated corticosteroid that consists of 6alpha,9-difluoro-11beta,17alpha-dihydroxy-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-16-methyl-3-oxoandrosta-1,4-diene bearing a propionyl substituent at position 17; has anti-inflammatory, anti-asthmatic and anti-allergic activity. | fluticasone propionate |
| methylprednisolone | The 6alpha-stereoisomer of 6-methylprednisolone. | 6alpha-methylprednisolone |
| phentermine | phentermine | |
| prednisolone | A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone. | prednisolone |
| prednisone | A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid. | prednisone |
| tetrahydropalmatine | A berberine alkaloid obtained by formal addition of two molecules of hydrogen to the pyridine ring of palmatine. | tetrahydropalmatine |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 37,911 (39.63) | 18.7374 |
| 1990's | 16,564 (17.32) | 18.2507 |
| 2000's | 18,031 (18.85) | 29.6817 |
| 2010's | 18,289 (19.12) | 24.3611 |
| 2020's | 4,866 (5.09) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 12,302 (11.40%) | 5.53% |
| Reviews | 7,359 (6.82%) | 6.00% |
| Case Studies | 32,991 (30.57%) | 4.05% |
| Observational | 383 (0.35%) | 0.25% |
| Other | 54,876 (50.85%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| acetylcholinesterase | Homo sapiens (human) | Potency | 89.3584 | 1 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 2.3599 | 12 | 93 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 8.3958 | 2 | 2 |
| Ataxin-2 | Homo sapiens (human) | Potency | 0.0247 | 1 | 2 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 0.6012 | 1 | 1 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 0.0247 | 1 | 2 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 0.7079 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 11.9467 | 2 | 2 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 0.0009 | 1 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 63.0957 | 1 | 1 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 18.7126 | 1 | 2 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 26.8370 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 31.6228 | 2 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 3.0578 | 2 | 5 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 3.1162 | 1 | 12 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 7.7429 | 7 | 34 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 68.8687 | 1 | 1 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 24.6209 | 6 | 13 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 14.8303 | 4 | 5 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 18.6548 | 1 | 1 |
| G | Vesicular stomatitis virus | Potency | 18.7126 | 1 | 2 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| GALC protein | Homo sapiens (human) | Potency | 0.7079 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| geminin | Homo sapiens (human) | Potency | 0.6478 | 1 | 2 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 7.1609 | 2 | 9 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 1.1328 | 4 | 28 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 0.3020 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 18.7126 | 1 | 2 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 8.6410 | 1 | 2 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 11.8605 | 3 | 3 |
| IDH1 | Homo sapiens (human) | Potency | 22.7265 | 1 | 2 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 18.7126 | 1 | 4 |
| Interferon beta | Homo sapiens (human) | Potency | 4.1733 | 3 | 9 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 100.0000 | 1 | 1 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 0.3162 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 57.3224 | 3 | 4 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 0.0566 | 2 | 6 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 54.9477 | 1 | 1 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 7.4978 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 3.5481 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 8.2860 | 1 | 4 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 32.1690 | 3 | 4 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 6.0120 | 1 | 1 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 0.0023 | 1 | 1 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 84.9214 | 1 | 1 |
| polyprotein | Zika virus | Potency | 18.6548 | 1 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
| PPM1D protein | Homo sapiens (human) | Potency | 0.0083 | 1 | 2 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 37.5775 | 2 | 7 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 50.1187 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 24.0048 | 3 | 17 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 0.0935 | 2 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 25.1136 | 3 | 9 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 17.6117 | 1 | 2 |
| TDP1 protein | Homo sapiens (human) | Potency | 22.8244 | 2 | 7 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 4.4668 | 1 | 1 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 21.2365 | 1 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 38.7277 | 1 | 1 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 7.0850 | 2 | 2 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 0.8913 | 1 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 41.5210 | 2 | 5 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 34.6654 | 1 | 1 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 112.2020 | 1 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 0.3020 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | Ki | 5.0000 | 1 | 1 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | Ki | 14.4000 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Bos taurus (cattle) | Ki | 300.0000 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | Ki | 280.0000 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | Ki | 370.0000 | 2 | 2 |
| Androgen receptor | Homo sapiens (human) | IC50 | 18.0000 | 2 | 2 |
| Androgen receptor | Rattus norvegicus (Norway rat) | IC50 | 26.4460 | 3 | 3 |
| Androgen receptor | Homo sapiens (human) | Ki | 2.6807 | 3 | 3 |
| Androgen receptor | Rattus norvegicus (Norway rat) | Ki | 17.7860 | 1 | 1 |
| Aromatase | Homo sapiens (human) | IC50 | 70,459,513.2611 | 39 | 40 |
| Aromatase | Rattus norvegicus (Norway rat) | IC50 | 20.1000 | 2 | 2 |
| Aromatase | Homo sapiens (human) | Ki | 1.3615 | 13 | 13 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 4 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 287.8300 | 3 | 10 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 4 |
| Cholesterol side-chain cleavage enzyme, mitochondrial | Homo sapiens (human) | IC50 | 80.0000 | 1 | 1 |
| Cholesterol side-chain cleavage enzyme, mitochondrial | Bos taurus (cattle) | IC50 | 29.6667 | 3 | 3 |
| Corticosteroid-binding globulin | Homo sapiens (human) | Ki | 0.0309 | 1 | 1 |
| Cytochrome P450 11B2, mitochondrial | Rattus norvegicus (Norway rat) | IC50 | 70.0000 | 2 | 3 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Cytochrome P450 2D1 | Rattus norvegicus (Norway rat) | IC50 | 529.0000 | 1 | 1 |
| Cytochrome P450 2D26 | Rattus norvegicus (Norway rat) | IC50 | 107.0000 | 1 | 1 |
| Cytochrome P450 2D3 | Rattus norvegicus (Norway rat) | IC50 | 1,754.0000 | 1 | 1 |
| Cytochrome P450 2D4 | Rattus norvegicus (Norway rat) | IC50 | 747.0000 | 1 | 1 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 65.4000 | 2 | 2 |
| Cytochrome P450 2J2 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | IC50 | 1.6300 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | Ki | 0.1920 | 2 | 2 |
| D(1B) dopamine receptor | Homo sapiens (human) | Ki | 0.3050 | 1 | 1 |
| D(2) dopamine receptor | Homo sapiens (human) | IC50 | 0.4500 | 1 | 1 |
| D(2) dopamine receptor | Homo sapiens (human) | Ki | 3.0625 | 2 | 2 |
| D(3) dopamine receptor | Homo sapiens (human) | Ki | 1.3710 | 1 | 1 |
| D(4) dopamine receptor | Homo sapiens (human) | Ki | 1.0000 | 1 | 1 |
| Delta-type opioid receptor | Mus musculus (house mouse) | IC50 | 0.2700 | 1 | 1 |
| Estrogen receptor | Homo sapiens (human) | IC50 | 40.0000 | 3 | 3 |
| Estrogen receptor | Homo sapiens (human) | Ki | 3.6667 | 3 | 3 |
| Estrogen receptor beta | Homo sapiens (human) | IC50 | 40.0000 | 3 | 3 |
| Estrogen receptor beta | Homo sapiens (human) | Ki | 1.0000 | 1 | 1 |
| Fatty acid-binding protein, liver | Rattus norvegicus (Norway rat) | Ki | 51.8300 | 2 | 2 |
| Glucocorticoid receptor | Homo sapiens (human) | IC50 | 0.0675 | 46 | 48 |
| Glucocorticoid receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0349 | 5 | 5 |
| Glucocorticoid receptor | Homo sapiens (human) | Ki | 0.0341 | 15 | 17 |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 0.3910 | 1 | 3 |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Ki | 0.1778 | 1 | 3 |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 0.3910 | 1 | 3 |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 0.1778 | 1 | 3 |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 0.3910 | 1 | 3 |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 0.1778 | 1 | 3 |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | IC50 | 0.3910 | 1 | 3 |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | Ki | 0.1778 | 1 | 3 |
| Mineralocorticoid receptor | Homo sapiens (human) | IC50 | 0.0517 | 6 | 6 |
| Mineralocorticoid receptor | Homo sapiens (human) | Ki | 0.0186 | 2 | 2 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 109.9925 | 1 | 4 |
| Phenylethanolamine N-methyltransferase | Bos taurus (cattle) | Ki | 435.3333 | 2 | 3 |
| Progesterone receptor | Homo sapiens (human) | IC50 | 5.1573 | 7 | 7 |
| Progesterone receptor | Homo sapiens (human) | Ki | 5.4286 | 7 | 7 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | Ki | 5.0000 | 1 | 2 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | IC50 | 0.2700 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | IC50 | 224.0000 | 1 | 2 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | IC50 | 0.0358 | 2 | 5 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | IC50 | 0.2222 | 2 | 2 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 0.0500 | 3 | 3 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 0.6310 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 0.1010 | 1 | 1 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | IC50 | 16.5959 | 1 | 1 |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | IC50 | 224.0000 | 1 | 1 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | Ki | 5.7280 | 1 | 1 |
| Steroid 17-alpha-hydroxylase/17,20 lyase | Homo sapiens (human) | IC50 | 60.0000 | 1 | 1 |
| Sterol O-acyltransferase 1 | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Thromboxane-A synthase | Homo sapiens (human) | IC50 | 18.5000 | 2 | 3 |
| Tissue factor | Homo sapiens (human) | IC50 | 0.0228 | 1 | 1 |
| Transporter | Rattus norvegicus (Norway rat) | IC50 | 0.9890 | 1 | 1 |
| Triosephosphate isomerase | Oryctolagus cuniculus (rabbit) | Ki | 1.4100 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 4 | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 5A | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 5B | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 6 | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 7 | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| Aromatase | Rattus norvegicus (Norway rat) | EC50 | 0.2600 | 1 | 1 |
| Glucocorticoid receptor | Homo sapiens (human) | EC50 | 0.0278 | 43 | 43 |
| Glucocorticoid receptor | Mus musculus (house mouse) | EC50 | 0.0046 | 2 | 2 |
| Glucocorticoid receptor | Rattus norvegicus (Norway rat) | EC50 | 0.0102 | 2 | 2 |
| Glucocorticoid receptor | Homo sapiens (human) | Kd | 0.0290 | 1 | 1 |
| Glutamine synthetase | Homo sapiens (human) | EC50 | 0.0320 | 1 | 1 |
| Histamine H1 receptor | Cavia porcellus (domestic guinea pig) | EC50 | 0.0026 | 1 | 1 |
| Mineralocorticoid receptor | Homo sapiens (human) | EC50 | 0.0010 | 2 | 2 |
| Nociceptin receptor | Rattus norvegicus (Norway rat) | EC50 | 0.0034 | 1 | 1 |
| Nuclear receptor subfamily 1 group I member 2 | Homo sapiens (human) | EC50 | 12.6000 | 1 | 1 |
| Nuclear receptor subfamily 1 group I member 2 | Rattus norvegicus (Norway rat) | EC50 | 4.0000 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Rattus norvegicus (Norway rat) | EC50 | 0.9900 | 1 | 1 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | EC50 | 0.0250 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | EC50 | 0.9900 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | EC50 | 0.2100 | 1 | 1 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | EC50 | 0.1400 | 1 | 1 |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | EC50 | 1.7650 | 1 | 1 |
| Trace amine-associated receptor 1 | Homo sapiens (human) | EC50 | 1.6270 | 4 | 5 |
| Trace amine-associated receptor 1 | Macaca mulatta (Rhesus monkey) | EC50 | 1.0100 | 1 | 1 |
| Trace amine-associated receptor 1 | Mus musculus (house mouse) | EC50 | 0.1039 | 5 | 5 |
| Trace amine-associated receptor 1 | Rattus norvegicus (Norway rat) | EC50 | 0.5328 | 6 | 6 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Aromatase | Homo sapiens (human) | Ka app | 0.1300 | 1 | 1 |
| Aromatase | Homo sapiens (human) | Km | 0.0900 | 2 | 2 |
| Aromatase | Homo sapiens (human) | Ks app | 0.1300 | 1 | 1 |
| Aromatase | Homo sapiens (human) | Log IC50 | 0.0034 | 1 | 1 |
| Glucocorticoid receptor | Homo sapiens (human) | Activity | 0.0024 | 1 | 1 |
| Glucocorticoid receptor | Homo sapiens (human) | ED50 | 0.0040 | 1 | 1 |
| Glucocorticoid receptor | Homo sapiens (human) | fEC50 | 0.0240 | 1 | 1 |
| Glucocorticoid receptor | Homo sapiens (human) | fIC20 | 0.0009 | 1 | 1 |
| Glucocorticoid receptor | Homo sapiens (human) | fIC30 | 0.0200 | 1 | 1 |
| Liver carboxylesterase 1 | Homo sapiens (human) | Km | 43.8000 | 1 | 1 |
| luciferase | Photuris pensylvanica (Pennsylania firefly) | AC50 | 52.0000 | 1 | 1 |
| Progesterone receptor | Homo sapiens (human) | Activity | 5.0000 | 1 | 1 |