Page last updated: 2024-08-05 11:21:16
p-quinones
A quinone in which the two oxo groups of the quinone are located para to each other on the 6-membered quinonoid ring.
ChEBI ID: 25830
Members (17)
| Member | Definition | Role |
|---|---|---|
| 1-hydroxyaklavinone | (1R,2R,4S)-2-ethyl-2,4,5,7,10-pentahydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylic acid methyl ester | |
| 2,5-di-tert-butylbenzoquinone | 2,5-di-tert-Butyl-1,4-benzoquinone | |
| 6-anilino-5,8-quinolinedione | A quinolone that is quinoline-5,8-dione in which the hydrogen at position 6 is replaced by an anilino group. | 6-anilino-5,8-quinolinedione |
| adriamycinol | A member of the class of tetracenequinones that is the major metabolite of the anthracycline doxorubicin, a chemotherapeutic agent effective against a broad range of malignant neoplasms. It is thought to exhibit cardiotoxic properties. | doxorubicinol |
| carubicin | A toxic anthracycline antibiotic that is produced by Actinomadura carminata and also has potent antineoplastic activity. | carminomycin |
| daunorubicin | A natural product found in Actinomadura roseola. | daunorubicin |
| dithianone | A naphthodithiin that is 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiin which is substituted by nitrile groups at positions 2 and 3. It is a broad spectrum fungicide used to control scab, downy mildew, rust, and leaf spot in the commercial growing of grapes and other fruit, citrus, coffee, and vegetables. | dithianon |
| eleutherin | Eleutherin | |
| epirubicin | An anthracycline that is the 4'-epi-isomer of doxorubicin. | 4'-epidoxorubicin |
| frenolicin b | frenolicin B | |
| komaroviquinone | A tetracyclic diterpenoid isolated from Dracocephalum komarovii and has been shown to exhibit trypanocidal activity. | komaroviquinone |
| nanaomycin a | A pyranonaphthoquinone antibiotic from strain OS-3966 of Streptomyces rosa var. notoensis. | nanaomycin A |
| pradimicin a | A member of the class of pradimicins that is isolated from the cultured broth of Actinomadura hibisca No. P157-2 (ATCC 53557). | pradimicin A |
| tetrangulol | A member of the class of tetraphenes that is tetraphene-7,12-dione substituted by hydroxy groups at positions 1 and 8 and a methyl group at position 3. | tetrangulol |
| topopyrone c | A naphthochromene that is 4H-naphtho[2,3-h]chromene-4,7,12-trione substituted by hydroxy groups at positions 5, 9 and 11 and a methyl group at position 2. It is isolated from fungal strains Phoma and Penicillium and acts as an inhibitor of the enzyme topoisomerase I. | topopyrone C |
| versicolorin a | An organic heteropentacyclic compound that is 3a,12a-dihydroanthra[2,3-b]furo[3,2-d]furan-5,10-dione carrying three hydroxy substituents at positions 4, 6 and 8. | versicolorin A |
| versicolorin c | An organic heteropentacyclic compound that is 2,3,3a,12a-tetrahydroanthra[2,3-b]furo[3,2-d]furan-5,10-dione carrying three hydroxy substituents at positions 4, 6 and 8. | versicolorin B |
Research
Studies (13,366)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 3,540 (26.49) | 18.7374 |
| 1990's | 3,373 (25.24) | 18.2507 |
| 2000's | 3,121 (23.35) | 29.6817 |
| 2010's | 2,743 (20.52) | 24.3611 |
| 2020's | 589 (4.41) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 2,735 (18.91%) | 5.53% |
| Reviews | 703 (4.86%) | 6.00% |
| Case Studies | 1,195 (8.26%) | 4.05% |
| Observational | 35 (0.24%) | 0.25% |
| Other | 9,795 (67.72%) | 84.16% |