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amphetamines
Amines that constitute a class of central nervous system stimulants based on the structure of the parent amphetamine 1-phenylpropan-2-amine.
ChEBI ID: 35338
Members (40)
| Member | Definition | Role |
|---|---|---|
| 2,5-dimethoxy-4-ethylamphetamine | 2,5-Dimethoxy-4-ethylamphetamine | |
| 3-o-methyl-alpha-methyldopamine | 3-O-Methyl-a-methyldopamine | |
| 4-[(2S)-2-[2-(4-ethoxyphenyl)ethylamino]-3-[[(2S)-1-(methylamino)hexan-2-yl]amino]propyl]phenol | 4-[(2S)-2-[2-(4-ethoxyphenyl)ethylamino]-3-[[(2S)-1-(methylamino)hexan-2-yl]amino]propyl]phenol | |
| 4-iodo-2,5-dimethoxyphenylisopropylamine | An organoiodine compound that is amphetamine bearing two methoxy substituents at positions 2 and 5 as well as an iodo substituent at position 4. | 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine |
| afuresertib | N-[(2S)-1-amino-3-(3-fluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-2-methyl-3-pyrazolyl)-2-thiophenecarboxamide | |
| alpha-methyldopamine | a-Methyldopamine | |
| an 1 | amfetaminil | |
| benzphetamine | Dextroamphetamine in which the the hydrogens attached to the amino group are substituted by a methyl and a benzyl group. A sympathomimetic agent with properties similar to dextroamphetamine, it is used as its hydrochloride salt in the treatment of obesity. | benzphetamine |
| chloramphenicol succinate | Chloramphenicol succinate | |
| chlorphentermine | Chlorphentermine | |
| cloforex | cloforex | |
| clortermine | clortermine | |
| desmethylselegiline | Norselegiline | |
| dimethylamphetamine | Dimethylamphetamine | |
| ethylamphetamine | etilamfetamine | |
| fenproporex | fenproporex | |
| furfenorex | furfenorex | |
| lopinavir | A dicarboxylic acid diamide that is amphetamine is substituted on nitrogen by a (2,6-dimethylphenoxy)acetyl group and on the carbon alpha- to nitrogen by a (1S,3S)-1-hydroxy-3-{[(2S)-3-methyl-2-(2-oxotetrahydropyrimidin-1-yl)butanoyl]amino}-4-phenylbutyl group. An antiretroviral of the protease inhibitor class, it is used against HIV infections as a fixed-dose combination with another protease inhibitor, ritonavir. | lopinavir |
| mefenorex | mefenorex | |
| mephedrone | An aromatic ketone that is propiophenone substituted at C-4 and at C-beta with methyl and methylamino groups respectively. It is a synthetic stimulant and entactogen drug of the amphetamine and cathinone classes. | mephedrone |
| mephentermine | mephentermine | |
| methamphetamine | A member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent. | methamphetamine |
| methoxamine | An amphetamine in which the parent 1-phenylpropan-2-amine skeleton is substituted at position 1 with an hydroxy group and the phenyl ring is 2- and 5-substituted with methoxy groups. It is an antihypotensive agent (pressor), an agonist acting directly at alpha-adrenoceptors with selectivity for the alpha-1 adrenoceptor subtype similar to phenylephrine . | methoxamine |
| methoxyphenamine | An amphetamine methylated on nitrogen and with the phenyl ring methoxylated at C-2. A beta-adrenergic receptor agonist, it is used as a bronchodilator. | methoxyphenamine |
| N-(5-bromo-2-thiazolyl)-3-phenyl-2-(1-pyrrolyl)propanamide | N-(5-bromo-2-thiazolyl)-3-phenyl-2-(1-pyrrolyl)propanamide | |
| N-[1-(1H-benzimidazol-2-yl)-2-phenylethyl]-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-oxo-3-pyrrolidinecarboxamide | N-[1-(1H-benzimidazol-2-yl)-2-phenylethyl]-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-oxo-3-pyrrolidinecarboxamide | |
| n-acetylamphetamine | N-acetylamphetamine | |
| n-benzoylphenylalanylphenylalinol acetate | aurantiamide acetate | |
| n-methyl-3,4-methylenedioxyamphetamine | A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5. | 3,4-methylenedioxymethamphetamine |
| n-methylephedrine | Methylephedrine | |
| n,alpha-diethylphenylethylamine | (+/-)-n-ethyl-1-phenyl-2-butylamine | |
| norfenfluramine | 1-[3-(trifluoromethyl)phenyl]-2-propanamine | |
| norfenfluramine | (2S)-1-[3-(trifluoromethyl)phenyl]-2-propanamine | |
| norpseudoephedrine | An amphetamine that is propylbenzene substituted by a hydroxy group at position 1 and by an amino group at position 2 (the 1S,2S-stereoisomer). | cathine |
| p-hydroxyamphetamine | 4-(2-aminopropyl)phenol | |
| pheniprazine | pheniprazine | |
| phenylalaninol | An amino alcohol resulting from the formal reduction of the carboxy group of L-phenylalanine to the corresponding alcohol. | L-phenylalaninol |
| phenylpropanolamine | An amphetamine that is propylbenzene substituted by a hydroxy group at position 1 and by an amino group at position 2 (the 1R,2S-stereoisomer). It is a plant alkaloid. | (-)-norephedrine |
| pholedrine | pholedrine | |
| prolintane | prolintane |
Research
Studies (22,148)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 4,534 (20.47) | 18.7374 |
| 1990's | 3,001 (13.55) | 18.2507 |
| 2000's | 5,968 (26.95) | 29.6817 |
| 2010's | 6,108 (27.58) | 24.3611 |
| 2020's | 2,537 (11.45) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 1,619 (6.46%) | 5.53% |
| Reviews | 1,794 (7.16%) | 6.00% |
| Case Studies | 1,443 (5.76%) | 4.05% |
| Observational | 110 (0.44%) | 0.25% |
| Other | 20,083 (80.17%) | 84.16% |