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amphetamines

Amines that constitute a class of central nervous system stimulants based on the structure of the parent amphetamine 1-phenylpropan-2-amine.

ChEBI ID: 35338

Members (40)

MemberDefinitionRole
2,5-dimethoxy-4-ethylamphetamine2,5-Dimethoxy-4-ethylamphetamine
3-o-methyl-alpha-methyldopamine3-O-Methyl-a-methyldopamine
4-[(2S)-2-[2-(4-ethoxyphenyl)ethylamino]-3-[[(2S)-1-(methylamino)hexan-2-yl]amino]propyl]phenol4-[(2S)-2-[2-(4-ethoxyphenyl)ethylamino]-3-[[(2S)-1-(methylamino)hexan-2-yl]amino]propyl]phenol
4-iodo-2,5-dimethoxyphenylisopropylamineAn organoiodine compound that is amphetamine bearing two methoxy substituents at positions 2 and 5 as well as an iodo substituent at position 4.2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine
afuresertibN-[(2S)-1-amino-3-(3-fluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-2-methyl-3-pyrazolyl)-2-thiophenecarboxamide
alpha-methyldopaminea-Methyldopamine
an 1amfetaminil
benzphetamineDextroamphetamine in which the the hydrogens attached to the amino group are substituted by a methyl and a benzyl group. A sympathomimetic agent with properties similar to dextroamphetamine, it is used as its hydrochloride salt in the treatment of obesity.benzphetamine
chloramphenicol succinateChloramphenicol succinate
chlorphentermineChlorphentermine
cloforexcloforex
clortermineclortermine
desmethylselegilineNorselegiline
dimethylamphetamineDimethylamphetamine
ethylamphetamineetilamfetamine
fenproporexfenproporex
furfenorexfurfenorex
lopinavirA dicarboxylic acid diamide that is amphetamine is substituted on nitrogen by a (2,6-dimethylphenoxy)acetyl group and on the carbon alpha- to nitrogen by a (1S,3S)-1-hydroxy-3-{[(2S)-3-methyl-2-(2-oxotetrahydropyrimidin-1-yl)butanoyl]amino}-4-phenylbutyl group. An antiretroviral of the protease inhibitor class, it is used against HIV infections as a fixed-dose combination with another protease inhibitor, ritonavir.lopinavir
mefenorexmefenorex
mephedroneAn aromatic ketone that is propiophenone substituted at C-4 and at C-beta with methyl and methylamino groups respectively. It is a synthetic stimulant and entactogen drug of the amphetamine and cathinone classes.mephedrone
mephenterminemephentermine
methamphetamineA member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent.methamphetamine
methoxamineAn amphetamine in which the parent 1-phenylpropan-2-amine skeleton is substituted at position 1 with an hydroxy group and the phenyl ring is 2- and 5-substituted with methoxy groups. It is an antihypotensive agent (pressor), an agonist acting directly at alpha-adrenoceptors with selectivity for the alpha-1 adrenoceptor subtype similar to phenylephrine .methoxamine
methoxyphenamineAn amphetamine methylated on nitrogen and with the phenyl ring methoxylated at C-2. A beta-adrenergic receptor agonist, it is used as a bronchodilator.methoxyphenamine
N-(5-bromo-2-thiazolyl)-3-phenyl-2-(1-pyrrolyl)propanamideN-(5-bromo-2-thiazolyl)-3-phenyl-2-(1-pyrrolyl)propanamide
N-[1-(1H-benzimidazol-2-yl)-2-phenylethyl]-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-oxo-3-pyrrolidinecarboxamideN-[1-(1H-benzimidazol-2-yl)-2-phenylethyl]-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-oxo-3-pyrrolidinecarboxamide
n-acetylamphetamineN-acetylamphetamine
n-benzoylphenylalanylphenylalinol acetateaurantiamide acetate
n-methyl-3,4-methylenedioxyamphetamineA member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.3,4-methylenedioxymethamphetamine
n-methylephedrineMethylephedrine
n,alpha-diethylphenylethylamine(+/-)-n-ethyl-1-phenyl-2-butylamine
norfenfluramine1-[3-(trifluoromethyl)phenyl]-2-propanamine
norfenfluramine(2S)-1-[3-(trifluoromethyl)phenyl]-2-propanamine
norpseudoephedrineAn amphetamine that is propylbenzene substituted by a hydroxy group at position 1 and by an amino group at position 2 (the 1S,2S-stereoisomer).cathine
p-hydroxyamphetamine4-(2-aminopropyl)phenol
pheniprazinepheniprazine
phenylalaninolAn amino alcohol resulting from the formal reduction of the carboxy group of L-phenylalanine to the corresponding alcohol.L-phenylalaninol
phenylpropanolamineAn amphetamine that is propylbenzene substituted by a hydroxy group at position 1 and by an amino group at position 2 (the 1R,2S-stereoisomer). It is a plant alkaloid.(-)-norephedrine
pholedrinepholedrine
prolintaneprolintane

Research

Studies (22,148)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19904,534 (20.47)18.7374
1990's3,001 (13.55)18.2507
2000's5,968 (26.95)29.6817
2010's6,108 (27.58)24.3611
2020's2,537 (11.45)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials1,619 (6.46%)5.53%
Reviews1,794 (7.16%)6.00%
Case Studies1,443 (5.76%)4.05%
Observational110 (0.44%)0.25%
Other20,083 (80.17%)84.16%