Roles > xenoestrogen
Page last updated: 2024-08-05 15:18:19

xenoestrogen

A synthetic or semi-synthetic compound that has oestrogenic activity.

ChEBI ID: 76988

Members (11)

MemberDefinitionClass
4-octylphenolA member of the class of phenols that is phenol which is substituted at the para- position by an octyl group.4-octylphenol
4,4'-bisphenol fA bisphenol that is methane in which two of the hydrogens have been replaced by 4-hydroxyphenyl groups.bisphenol F
bisphenol aA bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.bisphenol A
chlorotrianisenechlorotrianisene
dienestrolAn olefinic compound that is hexa-2,4-diene substituted by 4-hydroxyphenyl groups at positions 3 and 4 respectively.dienestrol
diethylstilbestrolAn olefinic compound that is trans-hex-3-ene in which the hydrogens at positions 3 and 4 have been replaced by p-hydroxyphenyl groups.diethylstilbestrol
estradiol 3-benzoateA benzoate ester resulting from the formal condensation of benzoic acid with the phenolic hydroxy group of 17beta-estradiol.17beta-estradiol 3-benzoate
ethinyl estradiolA 3-hydroxy steroid that is estradiol substituted by a ethynyl group at position 17. It is a xenoestrogen synthesized from estradiol and has been shown to exhibit high estrogenic potency on oral administration.17alpha-ethynylestradiol
mestranolA terminal acetylenic compound that is (17alpha)-17-ethynylestra-1(10),2,4-triene substituted by a methoxy group at position 3 and a hydroxy group at position 17.mestranol
mono-benzyl phthalateA phthalic acid monoester resulting from the formal condensation of one of the carboxy groups of phthalic acid with the hydroxy group of benzyl alcohol. It is a major metabolite of the plasticiser butyl benzyl phthalate (BBP).monobenzyl phthalate
quinestrolquinestrol

Research

Studies (26,487)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-199011,080 (41.83)18.7374
1990's2,479 (9.36)18.2507
2000's4,114 (15.53)29.6817
2010's6,365 (24.03)24.3611
2020's2,449 (9.25)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials2,225 (7.51%)5.53%
Reviews1,587 (5.35%)6.00%
Case Studies995 (3.36%)4.05%
Observational25 (0.08%)0.25%
Other24,806 (83.70%)84.16%

Protein Targets (237)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1Homo sapiens (human)Potency19.702012
15-lipoxygenase, partialHomo sapiens (human)Potency12.589311
67.9K proteinVaccinia virusPotency16.348223
acetylcholinesteraseHomo sapiens (human)Potency57.300523
activating transcription factor 6Homo sapiens (human)Potency43.867715
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency32.059413
Alpha-synucleinHomo sapiens (human)Potency35.481311
AR proteinHomo sapiens (human)Potency19.086012110
aryl hydrocarbon receptorHomo sapiens (human)Potency50.593225
ATAD5 protein, partialHomo sapiens (human)Potency24.514422
Ataxin-2Homo sapiens (human)Potency76.958811
ATP-dependent phosphofructokinaseTrypanosoma brucei brucei TREU927Potency15.848911
ATPase family AAA domain-containing protein 5Homo sapiens (human)Potency76.958811
bromodomain adjacent to zinc finger domain 2BHomo sapiens (human)Potency79.432811
caspase 7, apoptosis-related cysteine proteaseHomo sapiens (human)Potency35.780514
caspase-3Cricetulus griseus (Chinese hamster)Potency54.815311
caspase-3Homo sapiens (human)Potency35.780514
Caspase-7Cricetulus griseus (Chinese hamster)Potency54.815311
Cellular tumor antigen p53Homo sapiens (human)Potency27.8531319
cellular tumor antigen p53 isoform aHomo sapiens (human)Potency23.735822
Chain A, 2-oxoglutarate OxygenaseHomo sapiens (human)Potency29.315713
Chain A, Beta-lactamaseEscherichia coli K-12Potency112.202011
Chain A, CruzipainTrypanosoma cruziPotency16.838515
Chain A, Ferritin light chainEquus caballus (horse)Potency18.028313
Chain A, HADH2 proteinHomo sapiens (human)Potency30.462023
Chain A, JmjC domain-containing histone demethylation protein 3AHomo sapiens (human)Potency50.118711
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASEHomo sapiens (human)Potency17.220612
Chain B, HADH2 proteinHomo sapiens (human)Potency30.462023
chromobox protein homolog 1Homo sapiens (human)Potency82.783415
cytochrome P450 2C19 precursorHomo sapiens (human)Potency0.100011
cytochrome P450 2C9, partialHomo sapiens (human)Potency17.278519
cytochrome P450 2D6Homo sapiens (human)Potency23.251514
cytochrome P450 3A4 isoform 1Homo sapiens (human)Potency14.319428
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency7.960817
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency33.9005111
Disintegrin and metalloproteinase domain-containing protein 17Homo sapiens (human)Potency25.118911
DNA dC->dU-editing enzyme APOBEC-3G isoform 1Homo sapiens (human)Potency19.952611
estrogen nuclear receptor alphaHomo sapiens (human)Potency18.993912130
estrogen receptor 2 (ER beta)Homo sapiens (human)Potency15.9952333
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency36.7258985
EWS/FLI fusion proteinHomo sapiens (human)Potency28.309044
farnesoid X nuclear receptorHomo sapiens (human)Potency33.6324316
flap endonuclease 1Homo sapiens (human)Potency35.481311
Fumarate hydrataseHomo sapiens (human)Potency22.387211
GVesicular stomatitis virusPotency17.278519
GABA theta subunitRattus norvegicus (Norway rat)Potency14.319414
GALC proteinHomo sapiens (human)Potency1.584911
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)Potency14.319414
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)Potency14.319414
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)Potency14.319414
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)Potency14.319414
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)Potency14.319414
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)Potency14.319414
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)Potency14.319414
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)Potency14.319414
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)Potency14.319414
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)Potency14.319414
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)Potency14.319414
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)Potency14.319414
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)Potency14.319414
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)Potency14.319414
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)Potency14.319414
gemininHomo sapiens (human)Potency22.0162216
GLI family zinc finger 3Homo sapiens (human)Potency21.8424321
glp-1 receptor, partialHomo sapiens (human)Potency19.029124
GLS proteinHomo sapiens (human)Potency37.646012
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency20.0447531
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency34.6614112
GTP-binding nuclear protein Ran isoform 1Homo sapiens (human)Potency23.109311
Guanine nucleotide-binding protein GHomo sapiens (human)Potency10.000011
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)Homo sapiens (human)Potency44.668411
heat shock protein beta-1Homo sapiens (human)Potency39.776327
Histamine H2 receptorCavia porcellus (domestic guinea pig)Potency15.848912
histone acetyltransferase KAT2A isoform 1Homo sapiens (human)Potency31.622811
Histone H2A.xCricetulus griseus (Chinese hamster)Potency53.530625
histone-lysine N-methyltransferase 2A isoform 2 precursorHomo sapiens (human)Potency10.000012
HLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)Potency17.278519
huntingtin isoform 2Homo sapiens (human)Potency11.220211
hypoxia-inducible factor 1 alpha subunitHomo sapiens (human)Potency42.6326211
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)Homo sapiens (human)Potency27.698633
IDH1Homo sapiens (human)Potency16.128214
importin subunit beta-1 isoform 1Homo sapiens (human)Potency23.109311
Inositol hexakisphosphate kinase 1Homo sapiens (human)Potency17.2785118
Inositol monophosphatase 1Rattus norvegicus (Norway rat)Potency5.011911
Integrin alpha-IIbHomo sapiens (human)Potency15.848911
Integrin beta-3Homo sapiens (human)Potency15.848911
Interferon betaHomo sapiens (human)Potency24.9071313
interleukin 8Homo sapiens (human)Potency74.978012
lamin isoform A-delta10Homo sapiens (human)Potency6.472619
lethal factor (plasmid)Bacillus anthracis str. A2012Potency20.483912
LuciferasePhotinus pyralis (common eastern firefly)Potency32.4003315
lysosomal alpha-glucosidase preproproteinHomo sapiens (human)Potency34.411724
Microtubule-associated protein tauHomo sapiens (human)Potency25.194026
mitogen-activated protein kinase 1Homo sapiens (human)Potency25.202723
muscleblind-like protein 1 isoform 1Homo sapiens (human)Potency79.432811
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)Potency34.411712
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)Potency34.411712
neuropeptide S receptor isoform AHomo sapiens (human)Potency10.266312
nonstructural protein 1Influenza A virus (A/WSN/1933(H1N1))Potency6.037412
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency34.9470431
nuclear factor erythroid 2-related factor 2 isoform 2Homo sapiens (human)Potency23.262612
nuclear factor NF-kappa-B p105 subunit isoform 1Homo sapiens (human)Potency50.118711
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_aHomo sapiens (human)Potency35.485519
Nuclear receptor ROR-gammaHomo sapiens (human)Potency32.594815
nuclear receptor ROR-gamma isoform 1Mus musculus (house mouse)Potency14.733422
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency25.7293335
P53Homo sapiens (human)Potency50.118711
peripheral myelin protein 22Rattus norvegicus (Norway rat)Potency17.235514
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency36.3544521
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency35.6970510
plasminogen precursorMus musculus (house mouse)Potency10.000011
polyproteinZika virusPotency22.387211
Polyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)Potency15.848911
potassium voltage-gated channel subfamily H member 2 isoform dHomo sapiens (human)Potency26.484513
PPM1D proteinHomo sapiens (human)Potency32.999312
pregnane X nuclear receptorHomo sapiens (human)Potency31.1896326
pregnane X receptorRattus norvegicus (Norway rat)Potency53.377113
progesterone receptorHomo sapiens (human)Potency18.4326328
Rap guanine nucleotide exchange factor 3Homo sapiens (human)Potency79.432811
Rap guanine nucleotide exchange factor 4Homo sapiens (human)Potency24.567612
RAR-related orphan receptor gammaMus musculus (house mouse)Potency32.5803226
regulator of G-protein signaling 4Homo sapiens (human)Potency70.794611
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency31.0593328
retinoid X nuclear receptor alphaHomo sapiens (human)Potency28.9738412
serine-protein kinase ATM isoform aHomo sapiens (human)Potency17.782811
serine/threonine-protein kinase PLK1Homo sapiens (human)Potency29.934911
SMAD family member 2Homo sapiens (human)Potency39.476112
SMAD family member 3Homo sapiens (human)Potency39.476112
Smad3Homo sapiens (human)Potency15.848911
snurportin-1Homo sapiens (human)Potency23.109311
Spike glycoproteinSevere acute respiratory syndrome-related coronavirusPotency21.421512
survival motor neuron protein isoform dHomo sapiens (human)Potency18.354014
TAR DNA-binding protein 43Homo sapiens (human)Potency30.305113
TDP1 proteinHomo sapiens (human)Potency19.0917227
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency24.4052333
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency30.530015
thyroid stimulating hormone receptorHomo sapiens (human)Potency26.1262630
ubiquitin carboxyl-terminal hydrolase 2 isoform aHomo sapiens (human)Potency25.118911
urokinase plasminogen activator surface receptor precursorMus musculus (house mouse)Potency10.000011
urokinase-type plasminogen activator precursorMus musculus (house mouse)Potency10.000011
USP1 protein, partialHomo sapiens (human)Potency54.666116
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency29.6817210
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency19.442144
vitamin D3 receptor isoform VDRAHomo sapiens (human)Potency89.125111
Voltage-dependent calcium channel gamma-2 subunitMus musculus (house mouse)Potency34.6614112
VprHuman immunodeficiency virus 1Potency51.453212

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Rattus norvegicus (Norway rat)IC50960.000011
5-hydroxytryptamine receptor 2AHomo sapiens (human)IC504.790011
5-hydroxytryptamine receptor 2AHomo sapiens (human)Ki1.369011
5-hydroxytryptamine receptor 2BHomo sapiens (human)IC507.352512
5-hydroxytryptamine receptor 2BHomo sapiens (human)Ki4.678512
5-hydroxytryptamine receptor 2CHomo sapiens (human)IC5050.819011
5-hydroxytryptamine receptor 2CHomo sapiens (human)Ki26.619011
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)IC5050.819011
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)Ki26.619011
5-hydroxytryptamine receptor 6Homo sapiens (human)IC509.156012
5-hydroxytryptamine receptor 6Homo sapiens (human)Ki4.251012
AcetylcholinesteraseHomo sapiens (human)IC5018.510512
Adenosine receptor A1Homo sapiens (human)IC502.856011
Adenosine receptor A1Homo sapiens (human)Ki1.666011
Adenosine receptor A2aHomo sapiens (human)IC5017.458713
Adenosine receptor A2aHomo sapiens (human)Ki9.801313
Adenosine receptor A3Homo sapiens (human)IC5015.731814
Adenosine receptor A3Homo sapiens (human)Ki8.892214
Aldehyde oxidaseHomo sapiens (human)IC500.515012
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)IC5016.917816
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)Ki16.778316
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)IC5015.731814
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)Ki8.892214
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)IC5015.731814
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)Ki8.892214
Alpha-1D adrenergic receptorHomo sapiens (human)IC5010.826011
Alpha-1D adrenergic receptorHomo sapiens (human)Ki5.321011
Alpha-2A adrenergic receptorHomo sapiens (human)IC5014.207512
Alpha-2A adrenergic receptorHomo sapiens (human)Ki5.327512
Alpha-2B adrenergic receptorHomo sapiens (human)IC5012.097012
Alpha-2B adrenergic receptorHomo sapiens (human)Ki5.522512
Alpha-2C adrenergic receptorHomo sapiens (human)IC5018.011713
Alpha-2C adrenergic receptorHomo sapiens (human)Ki2.617013
Androgen receptorHomo sapiens (human)IC505.900011
Androgen receptorRattus norvegicus (Norway rat)IC5020.195228
Androgen receptorRattus norvegicus (Norway rat)Ki7.687214
ATP-binding cassette sub-family C member 3Homo sapiens (human)IC50133.000011
Beta-1 adrenergic receptorHomo sapiens (human)IC5022.088011
Beta-1 adrenergic receptorHomo sapiens (human)Ki12.755011
Bile salt export pumpHomo sapiens (human)IC5012.000022
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)IC500.500022
Canalicular multispecific organic anion transporter 1Homo sapiens (human)IC50133.000011
Cannabinoid receptor 1Homo sapiens (human)IC5028.540011
Cannabinoid receptor 1Homo sapiens (human)Ki22.532011
Carbonic anhydrase 1Homo sapiens (human)IC5091.500012
Carbonic anhydrase 2Homo sapiens (human)IC5091.500012
Cysteinyl leukotriene receptor 1Homo sapiens (human)IC5017.745011
Cysteinyl leukotriene receptor 1Homo sapiens (human)Ki8.872011
Cytochrome P450 2B1Rattus norvegicus (Norway rat)Ki11.000011
Cytochrome P450 2B6Homo sapiens (human)Ki0.850022
Cytochrome P450 3A4Homo sapiens (human)Ki18.000011
D(1A) dopamine receptorHomo sapiens (human)IC507.763011
D(1A) dopamine receptorHomo sapiens (human)Ki3.882011
D(2) dopamine receptorHomo sapiens (human)IC5013.321011
D(2) dopamine receptorHomo sapiens (human)Ki4.440011
D(3) dopamine receptorHomo sapiens (human)IC508.796011
D(3) dopamine receptorHomo sapiens (human)Ki2.987011
Delta-type opioid receptorHomo sapiens (human)IC502.718011
Delta-type opioid receptorHomo sapiens (human)Ki0.958011
Epidermal growth factor receptorHomo sapiens (human)IC5016.219011
Estrogen receptorHomo sapiens (human)IC502.98111118
Estrogen receptorHomo sapiens (human)Ki0.8581510
Estrogen receptor betaHomo sapiens (human)IC500.218777
Estrogen receptor betaHomo sapiens (human)Ki0.000333
Estrogen-related receptor gammaHomo sapiens (human)IC500.009022
Glucocorticoid receptorHomo sapiens (human)IC505.794713
Glucocorticoid receptorHomo sapiens (human)Ki2.633713
Glycine receptor subunit alpha-1Rattus norvegicus (Norway rat)IC505.794713
Glycine receptor subunit alpha-1Rattus norvegicus (Norway rat)Ki2.633713
Glycine receptor subunit alpha-2Rattus norvegicus (Norway rat)IC505.794713
Glycine receptor subunit alpha-2Rattus norvegicus (Norway rat)Ki2.633713
Glycine receptor subunit alpha-3Rattus norvegicus (Norway rat)IC505.794713
Glycine receptor subunit alpha-3Rattus norvegicus (Norway rat)Ki2.633713
Glycine receptor subunit betaRattus norvegicus (Norway rat)IC505.794713
Glycine receptor subunit betaRattus norvegicus (Norway rat)Ki2.633713
high affinity choline transporter 1 isoform aHomo sapiens (human)IC5012.589311
Kappa-type opioid receptorHomo sapiens (human)IC5015.228512
Kappa-type opioid receptorHomo sapiens (human)Ki6.091512
large T antigenBetapolyomavirus macacaeIC5070.100011
Mitogen-activated protein kinase 14Homo sapiens (human)IC5023.959512
Mu-type opioid receptorHomo sapiens (human)IC5016.273512
Mu-type opioid receptorHomo sapiens (human)Ki6.606012
Multidrug and toxin extrusion protein 1Homo sapiens (human)IC5021.100011
Multidrug and toxin extrusion protein 2Homo sapiens (human)IC5020.200011
Multidrug resistance-associated protein 4Homo sapiens (human)IC50133.000011
Muscarinic acetylcholine receptor M1Homo sapiens (human)IC5016.592012
Muscarinic acetylcholine receptor M1Homo sapiens (human)Ki3.996012
Muscarinic acetylcholine receptor M2Homo sapiens (human)IC5012.466011
Muscarinic acetylcholine receptor M2Homo sapiens (human)Ki4.432011
Muscarinic acetylcholine receptor M3Homo sapiens (human)IC5018.718012
Muscarinic acetylcholine receptor M3Homo sapiens (human)Ki3.967512
Muscarinic acetylcholine receptor M5Homo sapiens (human)IC5030.764011
Muscarinic acetylcholine receptor M5Homo sapiens (human)Ki22.102011
Nuclear receptor subfamily 1 group I member 2Homo sapiens (human)IC5014.600011
Nuclear receptor subfamily 1 group I member 3 Homo sapiens (human)IC503.000011
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)Ki0.000111
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)IC503.509514
Prostaglandin G/H synthase 1Homo sapiens (human)IC507.959512
Prostaglandin G/H synthase 2Homo sapiens (human)IC502.862011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1Oryctolagus cuniculus (rabbit)IC5083.000023
Sodium-dependent dopamine transporter Homo sapiens (human)IC507.284014
Sodium-dependent dopamine transporter Homo sapiens (human)Ki5.787214
Sodium-dependent noradrenaline transporter Homo sapiens (human)IC5016.917816
Sodium-dependent noradrenaline transporter Homo sapiens (human)Ki16.778316
Sodium-dependent serotonin transporterHomo sapiens (human)IC507.259516
Sodium-dependent serotonin transporterHomo sapiens (human)Ki3.856816
Solute carrier family 22 member 2Homo sapiens (human)IC502.200011
Substance-K receptorHomo sapiens (human)IC5013.491512
Substance-K receptorHomo sapiens (human)Ki4.497012
Sulfotransferase 1A1Homo sapiens (human)IC500.020011
Sulfotransferase 1A1Homo sapiens (human)Ki0.014333
Thromboxane-A synthase Homo sapiens (human)IC5035.204012
Tyrosine-protein kinase FynHomo sapiens (human)IC5018.613512
Tyrosine-protein kinase LckHomo sapiens (human)IC5022.054011
UDP-glucose 4-epimeraseHomo sapiens (human)IC5075.000011
UDP-glucuronosyltransferase 1A1 Homo sapiens (human)IC5032.500022
Vasopressin V1a receptorHomo sapiens (human)IC5025.925011
Vasopressin V1a receptorHomo sapiens (human)Ki10.401011

Activation Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
Chain A, Estrogen-related receptor gammaHomo sapiens (human)Kd0.224114
Estrogen receptorHomo sapiens (human)EC501.76131014
Estrogen receptorRattus norvegicus (Norway rat)EC502.431012
Estrogen receptor betaHomo sapiens (human)EC500.472178
Estrogen receptor betaRattus norvegicus (Norway rat)EC502.431012
Estrogen-related receptor gammaHomo sapiens (human)EC500.630022
GTP-binding protein RhebHomo sapiens (human)Kd1,800.000011
GTPase KRasHomo sapiens (human)Kd600.000011
Melatonin receptor type 1AHomo sapiens (human)EC50237.000011
Melatonin receptor type 1BHomo sapiens (human)EC50244.000011
ORF73Human gammaherpesvirus 8EC5075.000011
Sex hormone-binding globulinHomo sapiens (human)Kd0.651512
streptokinase A precursorStreptococcus pyogenes M1 GASEC502.320023
Sulfotransferase 1A1Homo sapiens (human)Kd0.252222

Other Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7Homo sapiens (human)AC502.895012
Sulfotransferase 1A1Homo sapiens (human)Km0.570022
UDP-glucuronosyltransferase 1A1 Homo sapiens (human)Km14.500012