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diaminopyridine

Compounds containing a pyridine skeleton substituted by two amino groups.

ChEBI ID: 51598

Members (3)

MemberDefinitionRole
2,4-diaminopyridine2,4-diaminopyridine
chir 98014A member of the class of aminopyrimidines that is pyrimidine substituted by {2-[(6-amino-5-nitropyridin-2-yl)amino]ethyl}amino, 2,4-dichlorophenyl, and 1H-imidazol-1-yl groups at positions 2, 4 and 5, respectively. It is a potent ATP-competitive inhibitor of GSK3alpha and GSK3beta (IC50 values of 0.65 and 0.58 nM, respectively).CHIR-98014
phenazopyridineA diaminopyridine that is 2,6-diaminopyridine substituted at position 3 by a phenylazo group. A local anesthetic that has topical analgesic effect on mucosa lining of the urinary tract. Its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity.phenazopyridine

Research

Studies (296)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990120 (40.54)18.7374
1990's26 (8.78)18.2507
2000's54 (18.24)29.6817
2010's63 (21.28)24.3611
2020's33 (11.15)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials24 (7.62%)5.53%
Reviews14 (4.44%)6.00%
Case Studies79 (25.08%)4.05%
Observational0 (0.00%)0.25%
Other198 (62.86%)84.16%