seco-cholestane

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ChEBI ID: 36818

Members (4)

Member	Definition	Role
calcipotriene	A seco-cholestane that is 26,27-cyclo-9,10-secocholesta-5,7,10,22-tetraene carrying additional hydroxy substituents at positions 1, 3 and 24. It is used (as its hydrate) in combination with betamethasone dipropionate, a corticosteroid, for the topical treatment of plaque psoriasis in adult patients.	calcipotriol
cholecalciferol	A hydroxy seco-steroid that is (5Z,7E)-9,10-secocholesta-5,7,10(19)-triene in which the pro-S hydrogen at position 3 has been replaced by a hydroxy group. It is the inactive form of vitamin D3, being hydroxylated in the liver to calcidiol (25-hydroxyvitamin D3), which is then further hydroxylated in the kidney to give calcitriol (1,25-dihydroxyvitamin D3), the active hormone.	calciol
paricalcitol		paricalcitol
previtamin d(3)	A hydroxy seco-steroid which is an intermediate in the production of vitamin D3 in human skin.	previtamin D3