Page last updated: 2024-08-05 13:17:29

seco-cholestane

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ChEBI ID: 36818

Members (4)

MemberDefinitionRole
calcipotrieneA seco-cholestane that is 26,27-cyclo-9,10-secocholesta-5,7,10,22-tetraene carrying additional hydroxy substituents at positions 1, 3 and 24. It is used (as its hydrate) in combination with betamethasone dipropionate, a corticosteroid, for the topical treatment of plaque psoriasis in adult patients.calcipotriol
cholecalciferolA hydroxy seco-steroid that is (5Z,7E)-9,10-secocholesta-5,7,10(19)-triene in which the pro-S hydrogen at position 3 has been replaced by a hydroxy group. It is the inactive form of vitamin D3, being hydroxylated in the liver to calcidiol (25-hydroxyvitamin D3), which is then further hydroxylated in the kidney to give calcitriol (1,25-dihydroxyvitamin D3), the active hormone.calciol
paricalcitolparicalcitol
previtamin d(3)A hydroxy seco-steroid which is an intermediate in the production of vitamin D3 in human skin.previtamin D3

Research

Studies (8,317)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19902,089 (25.12)18.7374
1990's892 (10.73)18.2507
2000's1,337 (16.08)29.6817
2010's2,916 (35.06)24.3611
2020's1,083 (13.02)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials1,525 (17.30%)5.53%
Reviews945 (10.72%)6.00%
Case Studies308 (3.49%)4.05%
Observational58 (0.66%)0.25%
Other5,977 (67.82%)84.16%