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nitrofuran antibiotic

A member of the class of furans in which the furan ring is substituted by a nitro group and which also has significant antibiotic properties.

ChEBI ID: 87230

Members (7)

MemberDefinitionRole
furazolidoneA member of the class of oxazolidines that is 1,3-oxazolidin-2-one in which the hydrogen attached to the nitrogen is replaced by an N-{[(5-nitro-2-furyl)methylene]amino} group. It has antibacterial and antiprotozoal properties, and is used in the treatment of giardiasis and cholera.furazolidone
furylfuramideA member of the class of acrylamides that is acrylamide which is substituted at positions 2 and 3 by 2-furyl and 5-nitro-2-furyl groups, respectively (the trans isomer). Formerly used as a food preservative, it was withdrawn from the market following suspicions of carcenogenicity.(Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide
nifursolnifursol
nifurtimoxNifurtimox
nifurtoinolAn imidazolidine-2,4-dione that is hydantoin substituted at position 1 by a [(5-nitro-2-furyl)methylene]amino group and at position 3 by a hydroxymethyl group.nifurtoinol
nitrofurantoinAn imidazolidine-2,4-dione that is hydantoin substituted at position 1 by a [(5-nitro-2-furyl)methylene]amino group. An antibiotic that damages bacterial DNA.nitrofurantoin
nitrofurazoneA semicarbazone resulting from the formal condensation of semicarbazide with 5-nitrofuraldehyde. A broad spectrum antibacterial drug, although with little activity against Pseudomonas species, it is used as a local application for burns, ulcers, wounds and skin infections.nitrofurazone

Research

Studies (4,560)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19902,587 (56.73)18.7374
1990's434 (9.52)18.2507
2000's497 (10.90)29.6817
2010's688 (15.09)24.3611
2020's354 (7.76)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials327 (6.48%)5.53%
Reviews339 (6.72%)6.00%
Case Studies362 (7.18%)4.05%
Observational11 (0.22%)0.25%
Other4,004 (79.40%)84.16%