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Osteoporosis

Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.

Synonyms(1)

Synonym
Osteoporosis

Research Excerpts

Overview

ExcerptReference
"Patchy osteoporosis is the primary roentgenologic manifestation of the reflex sympathetic dystrophy syndrome (RSDS)."( Bekerman, C; Genant, HK; Kozin, F; McCarty, DJ, 1976)
"Osteoporosis is no disease by itself but a result or a concomitant phenomenon of various diseases."( Krokowski, E, 1979)
"Osteoporosis is the result of the progressive loss of bone substance which occurs during a lifetime."( Camus, JP; Crouzet, J; Prier, A, 1979)
"Primary osteoporosis is a ubiquitous disease of unknown etiology."( Wallach, S, 1979)
"Primary osteoporosis is the ultimate consequence of progressive bone loss, which starts in the middle of the fourth decade."( Sandler, RB, 1978)
""Osteoporosis" is no disease by itself, but solely an anatomically equal result of various etiologic and pathogenetic influences on the bone structure or parts of same."( Jesserer, H, 1977)
"A high-turnover osteoporosis is proved by bone histomorphometry."( Dammann, HG; Kruse, HP; Kuhlencordt, F; Montz, R; Schreiber, HW, 1977)
"Osteoporosis is defined as 'too little normal bone', the disorder being rarer in children than adults."( Dent, CE, 1977)
"Osteoporosis is seen with increasing frequency in hemodialyzed patients."( David, DS, 1975)
"Osteoporosis is predisposed by amyothenia respectively in activity and is initiated by reduced blood circulation of the sustentaculum."( Fricke, M; Krokowski, E, 1975)
"Low-bone-turnover osteoporosis is a common complication of primary biliary cirrhosis (PBC)."( del Rio, L; Gómez, R; Guañabens, N; Muñoz, J; Parés, A; Roca, M; Rodés, J, 1992)
"Osteoporosis is characterized by a reduction in bone mass."( Matkovic, V, 1992)
"Osteoporosis is a recognized complication following partial gastrectomy and is more common than osteomalacia."( Ell, PJ; Hall, ML; Hobsley, M; Tovey, FI, 1991)
"Osteoporosis is the most common metabolic bone disorder in the United States."( Levin, RM, 1991)
"Osteoporosis is a major public health problem."( Nicholson, GC; Stewart, GO, 1991)
"Osteoporosis is a disease characterized by a reduction in bone density which predisposes to fracture after even minimal trauma."( Baylink, DJ; Dure-Smith, BA; Farley, SM; Kraenzlin, ME; Libanati, CR; Schulz, EE, 1991)
"Osteoporosis is an important medical condition which is expensive in morbidity and mortality."( Ullrich, I, 1991)
"Idiopathic juvenile osteoporosis is a rare cause of osteoporosis during childhood."( Baroncelli, GI; Bertelloni, S; Calderazzi, A; Perri, G; Saggese, G, 1991)
"Osteoporosis is a common disease that results in 1."( Rubin, CD, 1991)
"Osteoporosis is one of the most common complications of streak gonad syndrome (SGS), however its pathogenesis is still unclear."( Bösze, P; Holló, I; Horváth, C; Kollin, E; Lakatos, P; László, J; Tarján, G; Vargha, P; Zséli, J, 1991)
"Corticoid osteoporosis is the most important of the so-called secondary forms of osteoporosis."( Ringe, JD, 1990)
"Osteoporosis is a serious side effect of systemic treatment with steroids."( Medici, TC; Rüegsegger, P, 1990)
"Osteoporosis is a growing disease, and attention should be directed to possible means of preventing and treating this disease."( Christiansen, C, 1990)
"Once osteoporosis is established as a disease entity, a variety of medical therapies have proven efficacy."( Bockman, RS; Weinerman, SA, 1990)
"Osteoporosis is common in patients requiring long-term treatment with glucocorticoids."( Lukert, BP; Raisz, LG, 1990)
"Osteoporosis is a known consequence of anorexia nervosa (AN) in adults, but the mechanism of bone loss is not established, and there have been no studies of bone mass in women developing AN before attaining peak bone mass."( Biller, BM; Herzog, DB; Holzman, S; Klibanski, A; Rosenthal, DI; Saxe, V, 1989)
"Acute osteoporosis is known to occur after immobilization in spinal cord injured patients and is related to an early increase in osteoclastic bone resorption."( Alexandre, C; Chappard, D; Minaire, P; Morukov, BV; Palle, S; Riffat, G; Rodionova, SS; Vico, L, 1989)
"Osteoporosis is a major public health problem whose impact will only continue to increase in the United States."( Lindsay, R, 1989)
"Osteoporosis is a devastating, morbid, and costly condition whose ravages are felt most profoundly by women over age 70 years."( Greenspan, SL; Resnick, NM, 1989)
"Postmenopausal osteoporosis is a common disorder."( Huskisson, EC; Spector, TD, 1989)
"Although osteoporosis is an age-related disorder, the accelerated bone loss observed in postmenopausal women may be preventable with early diagnosis and adequate estrogen replacement."( Brooks, P; Burnier, AM; Martin, PL; Quigley, ME, 1987)
"Osteoporosis is clearly more easily prevented than treated."( Lindsay, R, 1988)
"When osteoporosis is already apparent on radiological examination, fluoride (+ calcium) is generally given over 3-4 years, while calcitonin therapy is appropriate in acute painful and rapidly progressive osteoporosis with fresh vertebral fractures."( Dambacher, MA, 1988)
"The severity of the osteoporosis is directly related to the severity of the calcium malabsorption."( Bridges, A; Deam, S; Horowitz, M; Morris, HA; Need, AG; Nordin, BE; Philcox, JC; Robertson, A; Seamark, RF, 1985)
"Prednisone-induced osteoporosis is very frequent in the long-term treatment of sarcoidosis (sarcoidosis 4:45-48, 1987)."( Montemurro, L; Rizzato, G; Schiraldi, G; Sisti, S; Tosi, G; Zanni, D, 1988)
"Osteoporosis is a disease leading to enhanced fragility of bone in association with minimal trauma."( Galanski, M; Hesch, RD; Prokop, M; Rittinghaus, EF, 1988)
"Osteoporosis is the most important consequence of ovarian failure because it causes considerable morbidity and mortality."( Cheang, A; Kottegoda, SR; Ratnam, SS, 1987)
"Postmenopausal osteoporosis is a common disorder associated with significant morbidity and mortality through fractures of the femoral neck, vertebrae and distal forearm."( Rodysill, KJ, 1987)
"Osteoporosis is a common condition of the elderly population that entails considerable morbidity and mortality."( Heidrich, F; Thompson, RS, 1987)
"Postmenopausal osteoporosis is a common disabling condition, which is almost completely preventable with oestrogen therapy."( Brincat, M; Savvas, M; Studd, JW, 1987)
"Osteoporosis is a major public health problem, and its prevalence may be increasing."( Lindsay, R, 1987)
"Prevention of osteoporosis is clearly the preferred approach, since treatment of the established disorder is less than satisfactory."( Lindsay, R, 1987)
"Osteoporosis is a common complication of corticosteroid therapy and it is associated with both decreased bone formation and increased bone resorption."( Hartley, TF; Need, AG; Nordin, BE; Philcox, JC, 1986)
"Osteoporosis is a major public health problem because the incidence of hip, wrist, and vertebral fractures associated with bone loss is high."( Bauwens, SF; Boh, LE; Drinka, PJ, 1986)
"Osteoporosis is a major public health problem, particularly for the postmenopausal woman."( Lindsay, R; Silverberg, SJ, 1987)
"Osteoporosis is extremely common in alcoholics whereas osteomalacia is exceptional."( Pitts, TO; Van Thiel, DH, 1986)
"Osteoporosis is a serious metabolic bone disorder that results in fractures of the wrist, hip and vertebrae."( Coralli, CH; Raisz, LG; Wood, CL, 1986)
"Regional migratory osteoporosis is a disorder of unknown etiology, characterized by successive episodes of joint pain, accompanied by localized osteoporosis."( Hodsman, AB; Mavichak, V; Murray, TM; Robert, NJ; Sutton, RA, 1986)
"The development of osteoporosis is multifactorial, but seems to arise mainly through reduction in bone formation and reduced dietary protein and calcium intake."( Bremer, G; Franck, H; Keck, E, 1986)
"Osteoporosis is the most common bone disorder in the United States."( Davies, R; Saha, S, 1985)
"This progressive osteoporosis is associated with and could well result from a steady decline in calcium absorption which is at least partially attributable to vitamin-D deficiency and reversible on vitamin-D treatment."( Nordin, BE, 1971)
"Osteoporosis is a common disorder in women."( Lukert, BP, 1982)
"Osteoporosis is a skeletal condition in which there is a loss of bone mass, evident radiographically by diffuse rarefaction or clinically by overt fractures."( Lane, JM; Vigorita, VJ, 1984)
"Osteoporosis is the reduction of expected bone mass."( Dixon, AS; Woolf, AD, 1984)
"Osteoporosis is a major public health problem."( Wingate, L, 1984)
"Osteoporosis is a common and important feature of rheumatoid disease which can be further influenced by the treatment administered."( Schorn, D, 1983)
"Osteoporosis is the most important finding."( Andria, G; Bartolomeo-De Iuri, A; Del Giudice, E; Palescandolo, P; Sartorio, R; Strisciuglio, P; Tamburrini, O, 1984)
"Osteoporosis is a major cause of disability in elderly subjects."( Johannesson, A; Raisz, LG, 1984)
"Post-menopausal osteoporosis is certainly one of the diseases that has been most widely investigated densitometrically."( Nuti, R; Righi, G; Turchetti, V, 1983)
"Osteoporosis is a prime example of a disease which is, at least partially, nutritionally related and of great importance in this population."( Hickler, RB; Wayne, KS, 1984)
"Osteoporosis is an accepted fact of the female's aging process."( Linnell, S; Morton, M; Oyster, N, 1984)
"Postmenopausal osteoporosis is a histologically heterogeneous disorder with morphologic expression in bone that cannot be predicted by single or combined routine clinical and laboratory parameters."( Avioli, LV; Bergfeld, MA; Murphy, WA; Teitelbaum, SL; Whyte, MP, 1982)
"Osteoporosis is not a disease in itself and, hence, the management and prognosis in any individual case depends on the aetiology."( Jesserer, H, 1982)
"Osteoporosis is the most important metabolic bone disease and places an increasing burden on the healthcare system."( Hosking, DJ; Lyons, AR; Patel, S, 1993)
"In conclusion, male osteoporosis is frequently associated with major risk factors."( Alvarez, L; Guañabens, N; Hernandez, MV; Martinez de Osaba, MJ; Monegal, A; Muñoz-Gomez, J; Peris, P; Suris, X, 1995)
"Osteoporosis is a common disorder affecting the health of many adults."( Pilbeam, CC; Prestwood, KM; Raisz, LG, 1995)
"Osteoporosis is best managed by prevention, with maximisation of peak bone density and reduction of subsequent bone loss."( Grill, V; Martin, TJ, 1995)
"Osteoporosis is a well-recognized complication of long-term heparin use."( Deschamps, P; Hirsh, J; Shaughnessy, SG; Young, E, 1995)
"Iatrogenic osteoporosis is a very common secondary osteoporosis is found in patients treated with large dosage of glucocorticosteroid of long duration."( Wang, JZ; Zheng, LM, 1994)
"Osteoporosis is defined pathologically as an absolute decrease in the amount of bone, leading to fracture after minimal trauma at the aged."( Okada, M; Yamazaki, Y, 1994)
"Osteoporosis is not a disease resulting from obvious deficiencies in vitamin D, calcium, and phosphate."( Bikle, DD, 1994)
"When osteoporosis is already established, there are the following strategies: diminishing patients anxiety, non-narcotic analgesics and early mobilization after acute vertebra compression."( Seitz, M, 1994)
"Osteoporosis is a serious health problem for women over 45 years of age."( Forsbach, G; Santos, A, 1994)
"Steroid-induced osteoporosis is characterized by both increased bone resorption and inhibition of bone formation."( Adami, S; Rossini, M, 1993)
"Osteoporosis is a disease that characteristically afflicts postmenopausal women."( Meacham, S; Taper, LJ; Volpe, SL, 1993)
"Osteoporosis is a multifactorial disease with dimensions of genetics, endocrine function, exercise and nutritional considerations."( Saltman, PD; Strause, LG, 1993)
"Osteoporosis is not usually considered to be reversible, as it is a consequence of the ageing process."( Montemurro, L; Rizzato, G, 1993)
"Osteoporosis is a major complication of long-term steroid use."( Chung, KC; Shen, WJ; Wang, GJ, 1995)
"Osteoporosis is greatly increasing in prevalence as the population ages."( Daly, PA, 1995)
"On a global scale, osteoporosis is a major and growing public health problem."( Chorev, M; Dresner-Pollak, R; Eshel, Y; Rosenblatt, M, 1995)
"Osteoporosis is a significant health problem and contributor to disability and premature mortality among older men."( Anderson, SJ; Cauley, JA; Charron, M; Glynn, NW; Kuller, LH; Meilahn, EN, 1995)
"Osteoporosis is a disease that plagues older individuals, particularly women."( Imrie, R; Licata, A; Lonzer, MD; Rogers, D; Secic, M; Worley, D, 1996)
"When osteoporosis is diagnosed in men or premenopausal women, underlying pathology could be considered."( Kemink, SA; Kloppenborg, PW; Smals, AG, 1996)
"Risk fractures for osteoporosis are numerous."( Wark, JD, 1996)
"Osteoporosis is an increasingly prevalent chronic and debilitating disease."( Kessenich, CR, 1996)
"Osteoporosis is a leading cause of disability and death in older Americans; women are at higher risk than men."( Cáceres, B; Haines, ST; Yancey, L, 1996)
"Osteoporosis is a common disease among patients undergoing transplantation."( Arranz, R; Carmona, L; Carvajal, I; Castañeda, S; Díaz, A; García-Vadillo, A, 1997)
"Osteoporosis is widely accepted as a "female disease" occurring primarily in postmenopausal women."( McGee, C, 1997)
"Osteoporosis is a public health scourge that is usually eminently preventable."( Deal, CL, 1997)
"Osteoporosis is a recognized complication of corticosteroid therapy."( Adachi, JD; Bensen, WG; Brown, J; Chines, AA; Hanley, D; Hodsman, A; Josse, R; Kendler, DL; Lentle, B; Olszynski, W; Ste-Marie, LG; Tenenhouse, A, 1997)
"Osteoporosis is a common and costly condition that can cause disability or death."( Watts, NB, 1997)
"In adolescence, osteoporosis is usually due to idiopathic juvenile osteoporosis or secondary to amenorrhoea or anorexia nervosa."( Naganathan, V; Sambrook, PN, 1997)
"Currently, primary osteoporosis is the most frequent metabolic disease in women after menopause [1]."( Becker, P; Brock, J; Dorfling, P; Sasse, T; Schuhr, T, 1998)
"Osteoporosis is a metabolic bone disease characterized by an increased risk of fractures, especially hip, wrist and vertebral fractures."( Hardouin, P, 1997)
"Osteoporosis is a major complication of long-term corticosteroid administration, but the magnitude of the effect in patients with chronic obstructive pulmonary disease (COPD) is not well defined."( Bender, E; Ensrud, KE; Genant, HK; Griffith, JM; McEvoy, CE; Niewoehner, DE; Yu, W, 1998)
"Osteoporosis is an old and continuing problem which has been a challenge to medical research and care throughout the history of mankind."( Fujita, T, 1997)
"Osteoporosis is a well-recognized adverse effect of corticosteroid therapy."( Cortet, B; Di Munno, O; Goemaere, S; Horlait, S; Hughes, RA; Ittner, J; Laan, R; Oriente, P; Pouillès, JM; Roux, C, 1998)
"Osteoporosis is present in over half of all patients with anorexia nervosa."( Grinspoon, S; Herzog, D; Klibanski, A, 1997)
"Although osteoporosis is generally regarded as a disease of women, up to 30% of hip fractures and 20% of vertebral fractures occur in men."( Boyle, IT; Compston, J; Cooper, C; Eastell, R; Fogelman, I; Francis, RM; Hosking, DJ; Purdie, DW; Ralston, S; Reeve, J; Reid, DM; Russell, RG; Stevenson, JC, 1998)
"Osteoporosis is common in patients with Cushing's disease and is likely due to an imbalance between bone formation and resorption."( Colao, A; Di Somma, C; Faggiano, A; Klain, M; Lombardi, G; Merola, B; Pivonello, R; Salvatore, M; Tripodi, FS, 1998)
"Osteoporosis is a common complication of long-term glucocorticoid therapy for which there is no well-proved preventive or restorative treatment."( Brown, JP; Czachur, M; Daifotis, AG; Delmas, PD; Emkey, R; Goemaere, S; Hawkins, F; Liberman, UA; Malice, MP; Saag, KG; Schnitzer, TJ; Thamsborg, G, 1998)
"Osteoporosis is the most frequent metabolic condition experienced by elderly individuals."( Devogelaer, JP, 1998)
"Osteoporosis is common in patients with chronic cholestatic liver disease, and atraumatic spinal fracture is a recognized complication after orthotopic liver transplantation."( Day, CP; Francis, RM; Hudson, M; Manas, DM; Reeves, HL, 1998)
"Osteoporosis is common in subjects over 70 years of age."( Constantin, A; Laroche, M; Mazières, B; Rolland, Y; Salles, JP; Tackzuck, J, 1998)
"Osteopenia and osteoporosis are frequent complications after kidney transplantation."( Grotz, WH; Kirste, G; Niessen, A; Olschewski, M; Reichelt, A; Rump, LC; Schmidt-Gayk, H; Schollmeyer, PJ, 1998)
"Osteoporosis is a well-known complication of thyrotoxicosis."( Carpinelli, A; Del Puente, AE; Esposito Del Puente, A; Lupoli, G; Nuzzo, V; Oriente, P; Rampone, E, 1998)
"Osteoporosis is one of the most serious bone-related pathogenic states, as it causes serious loss of quality of life."( Fukuzaki, K; Haraguchi, R; Horai, N; Izpisua-Belmonte, JC; Izumi, H; Kitajima, I; Maruyama, I; Minami, T; Miyado, K; Nagata, R; Nakamura, S; Suzuki, K; Tohno, Y; Toyoda, T; Yamada, G, 1998)
"Osteopenia or osteoporosis is common in patients with inflammatory bowel disease."( Sninsky, CA; Valentine, JF, 1999)
"Osteoporosis is less common among African Americans and Mexican Americans than among whites, and there is little evidence that dairy products have an effect on osteoporosis among racial minorities."( Barnard, ND; Bertron, P; Mills, M, 1999)
"Osteoporosis is a complex disease, and allelic variation in many other candidate-genes including those that encode growth factors, cytokines, calciotropic hormones, and bone matrix proteins are likely to also play a role and warrant systematic investigation."( Cauley, JA; Ferrell, RE; Zmuda, JM, 1999)
"Because osteoporosis is a common complication of primary biliary cirrhosis, we evaluated the effects of calcitriol (1alpha, 25-dihydroxyvitamin D3) on bone mineral density in 34 women with primary biliary cirrhosis (stage I disease in 16 patients, stage II in 9, stage III in 4, and stage IV in 5)."( Habu, D; Kuroki, T; Masaki, K; Nishiguchi, S; Ochi, H; Shiomi, S; Takeda, T, 1999)
"Osteoporosis is a major public health problem, responsible for a great number of fractures, associated with devastating costs to society."( Cocchi, D; Paganelli, C; Zaffe, D, 1999)
"Osteoporosis is associated with cirrhosis of the liver, but the effects of therapy for osteoporosis associated with cirrhosis are still controversial."( Habu, D; Kuroki, T; Masaki, K; Nishiguchi, S; Ochi, H; Shiomi, S; Takeda, T; Tanaka, T, 1999)
"Osteoporosis is very common in patients with end-stage pulmonary disease."( Addesso, V; Donovan, D; McGregor, C; Papadopoulos, A; Schulman, LL; Shane, E; Staron, RB, 1999)
"Idiopathic juvenile osteoporosis is a rare form of bone demineralization which occurs during childhood."( Bourrillon, A; Job-Deslandre, C; Joseph-Gaudry, J; Mazda, K, 1999)
"Osteoporosis is a serious complication of systemic glucocorticoid use."( Dunstan, CR; Gori, F; Hofbauer, LC; Khosla, S; Lacey, DL; Riggs, BL; Spelsberg, TC, 1999)
"Osteoporosis is for a long time a "silent" disease and the first symptoms such as back pain, loss of height, kyphosis, and fractures are late complications."( Bailer, U; de Zwaan, M; el Giamal, N; Kasper, S; Lennkh, C; Nagy, C; Strnad, A; Vytiska, E, 1999)
"In many countries osteoporosis is the most common metabolic bone diseases."( Châtel, R; Szathmári, M, 1999)
"Osteoporosis is a frequent complication of rheumatoid arthritis (RA)."( Acquista, CA; Cantatore, FP; Pipitone, V, 1999)
"Prevention of osteoporosis is a major public health issue."( Bounds, W; Davies, MC; Guillebaud, JG; Gulekli, B; Hall, M; Jacobs, HS; MacDougall, J; Overton, CE, 1999)
"Osteoporosis is a condition in which an imbalance appears between bone resorption and formation, with bone resorption exceeding formation."( Cantatore, FP; Pipitone, V, 1999)
"Osteoporosis is considered a systemic disease involving decreased bone mineral content and increased fracture risk."( Freudenthaler, F; Kudlacek, S; Willvonseder, R, 1999)
"Osteoporosis is generally considered an age-related reduction in the quantity and quality of bone, but it need not be considered an inevitable consequence of aging."( Dombrowski, HT, 2000)
"Osteoporosis is known to be associated with Crohn's disease."( Berdon, W; Bilezikian, JP; Gertner, JM; Harbison, M; Horlick, M; Levine, LS; Levy, J; Oberfield, SE; Thearle, M, 2000)
"Osteoporosis is an important age-related disease, constituting a major risk of fracture in the elderly, and in postmenopausal women in particular."( Payer, J, 2000)
"Osteoporosis is a major cause of morbidity worldwide."( Alfvén, T; Carlsson, MD; Elinder, CG; Grubb, A; Hellström, L; Järup, L; Persson, B; Pettersson, C; Schütz, A; Spång, G, 2000)
"Osteoporosis is a common complication of Cushing's disease/syndrome."( Crouzet, J; Fournier, JJ; Khanine, V; Luton, JP; Requeda, E; Simon, F, 2000)
"Thus, osteoporosis is frequent in Addison's disease and cortisoluria could be a useful tool to predict this complication."( Boutsen, Y; Devogelaer, JP; Donckier, J; Heureux, F; Jamart, J; Maiter, D, 2000)
"Osteoporosis is not a significant problem in the majority of patients with primary biliary cirrhosis (PBC)."( Schalm, SW; van Buuren, HR; Vleggaar, FP; Wolfhagen, FH, 2000)
"Osteoporosis is a common and costly disease."( Green, SS; Milott, JL; Schapira, MM, 2000)
"The pathogenesis of osteoporosis is complex and multifactorial."( Rosen, CJ, 2000)
"Osteoporosis is a significant problem in older men, 30% of all hip fractures occur in men and the mortality rate following hip fracture exceeds that of women."( Kenny, AM; Marcello, KM; Prestwood, KM; Raisz, LG, 2000)
"Osteopenia/osteoporosis is being increasingly reported as a complication of many chronic diseases, even in children."( Bardare, M; Bianchi, ML; Boncompagni, A; Brandi, ML; Cimaz, R; Corona, F; Falcini, F; Galbiati, E; Giuntini, D; Lepore, L; Luisetto, G; Picco, P; Zulian, F, 2000)
"Although osteoporosis is a significant public health problem for aging men as well as women, the cause of osteoporosis in men remains largely unknown."( Katz, MS, 2000)
"Osteoporosis is characterized by low bone mass and disruption of bone architecture, resulting in reduced bone strength and increased risk of fractures."( Bertoldo, F; Cappellini, MD; D'Agruma, L; Gasparini, P; Iolascon, A; Iolascon, G; Perrotta, S; Servedio, V; Siciliani, MC, 2000)
"Osteoporosis is a common complication of primary biliary cirrhosis but there is no accepted therapy for the osteoporosis."( Dickson, ER; Jorgensen, RA; Khosla, S; Lindor, KD; Tiegs, RD, 2000)
"As osteoporosis is a well known complication of endogenous and exogenous glucocorticoid excess, it is likely that patients with incidentally discovered adrenocortical adenomas have impaired bone mass due to subclinical hypercortisolism."( Alì, A; Angeli, A; Osella, G; Paccotti, P; Peretti, P; Reimondo, G; Terzolo, M, 2001)
"Osteoporosis is a well known side-effect of long-term treatment with glucocorticoids."( Ando, Y; Asano, Y; Kusano, E; Sasaki, N; Tsuda, E; Yano, K, 2001)
"Osteoporosis is a systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue."( Bonjour, JP; Ferrari, SL; Rizzoli, R, 2001)
"Drug treatments for osteoporosis are intended to inhibit bone resorption, reduce the rate of bone turnover, and increase bone mass."( Baran, D, 2001)
"Osteoporosis is a major health care problem internationally with important implications for health care costs, morbidity, and mortality."( Eisman, JA, 2001)
"Osteoporosis is a major source of morbidity after renal transplantation."( Erdal, R; Guvener, N; Haberal, M; Işiklar, I; Turan, M; Ugur, A, 2001)
"Osteoporosis is a well-documented complication of organ transplantation."( Adachi, JD; Arlen, DJ; Ioannidis, G; Lambert, K, 2001)
"Fractures due to osteoporosis are one of the major complications after heart transplantation, occurring mostly during the first 6 months after the graft, with an incidence ranging from 18% to 50% for vertebral fractures."( Berguer, DG; Burckhardt, P; Goy, JJ; Krieg, MA; Sandini, L; Seydoux, C; Thiébaud, D, 2001)
"Although osteoporosis is a typical feature of hypogonadism, the influence of testosterone levels and other hormonal factors on bone mass of eugonadal males is unknown."( Díaz-Curiel, M; Hawkins, F; Martínez Díaz-Guerra, G; Rapado, A; Ruiz Díaz, MA, 2001)
"Osteoporosis is a disease characterised by low bone mass, structural deterioration of bone and increased risk of fracture."( Morley, P; Whitfield, JF; Willick, GE, 2001)
"Osteoporosis is not a specific complication of PBC."( Bassendine, M; Francis, R; James, O; Jones, D; Newton, J; Prince, M; Rawlings, D, 2001)
"Osteoporosis is a serious complication of kidney transplantation."( Basadonna, GP; Bia, MJ; Brickel, HM; Cruz, DN; Friedman, AL; Gundberg, CG; Insogna, KL; Kliger, AS; Lorber, MI; Mitnick, MA; Simpson, CA; Wysolmerski, JJ, 2001)
"Osteoporosis is a major health problem for men and women."( Boling, EP, 2001)
"Osteoporosis is a disease affecting mainly women but also an increasing number of men."( Fassbender, WJ; Görtz, B, 2001)
"Generalized osteoporosis is a result of different causes and pathogenic mechanisms, which often combine forces to become clinically relevant."( Himmelreich, G; Loew, A; Riess, H, 2001)
"Osteoporosis is a prevalent condition among elderly women and is associated with an increased risk for fractures."( Bruder, JM; Rubin, CD; Wang, CY, 2001)
"Osteoporosis is increasingly recognised."( Diamond, T; Ferris, L; Fiatarone-Singh, M; Flicker, L; Lord, S; MacLennan, A; Nowson, C; O'Neil, S; Sambrook, P; Williamson, M, 2001)
"Osteoporosis is associated with significant morbidity and mortality in men."( Diamond, T; Ferris, L; Fiatarone-Singh, M; Flicker, L; Lord, S; MacLennan, A; Nowson, C; O'Neil, S; Sambrook, P; Williamson, M, 2001)
"Osteoporosis is a common extraintestinal complication of inflammatory bowel disease."( Lichtenstein, GR, 2001)
"Osteoporosis is a major clinical problem in chronic inflammatory diseases such as rheumatoid arthritis."( Armour, KE; Armour, KJ; Liew, FY; Ralston, SH; Reid, DM; van't Hof, RJ; Wei, XQ, 2001)
"Osteoporosis is a condition of increasing importance and prevalence in all parts of the world and particularly in Asia."( Mundy, GR, 2002)
"Since osteoporosis is mediated both by decreased osteoblastic bone formation and by increased osteoclastic bone resorption, we assessed whether oxidized lipids regulate the osteoclastic potential of marrow hematopoietic cells."( Demer, LL; Parhami, F; Territo, M; Tetradis, S; Tintut, Y; Tsingotjidou, A, 2002)
"Osteoporosis is a common manifestation of Cushing's syndrome, but the mechanisms responsible for this abnormality have not been defined."( Foss, MC; Lanna, CM; Montenegro, RM; Moreira, AC; Paula, FJ, 2002)
"Depression and osteoporosis are the commonest problems in elderly subjects."( Dhar, HL, 2001)
"Osteoporosis is a common disease among patients undergoing transplantation and a loss of bone mass is usually detected after bone marrow transplantation (BMT), particularly during the immediate post-BMT period."( Cha, BY; Han, JH; Kang, MI; Kang, SK; Kim, CC; Lee, KW; Lee, WY; Oh, ES; Oh, KW; Son, HY, 2002)
"Osteopenia and osteoporosis are thus frequently observed in patients with ANCA-associated vasculities."( Boomsma, MM; Karsijns, M; Kramer, AB; Piers, DA; Stegeman, CA; Tervaert, JW, 2002)
"Osteoporosis is defined as a progressive systemic skeletal disease characterised by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture."( García-Cohen, EC; Rodríguez-Martínez, MA, 2002)
"Osteoporosis is a substantial cause of morbidity and mortality in the United States."( Kirk, JK; Nichols, M; Spangler, JG, 2002)
"Osteoporosis is an important and debilitating side effect of androgen deprivation therapy, although precise estimates of its incidence, degree and cost are not completely elucidated."( Ross, RW; Small, EJ, 2002)
"Osteoporosis is a major public health problem all over the world."( Gera, I, 2002)
"Osteoporosis is under-diagnosed and under-treated in this group of elderly hip fracture patients."( De Geus-Wenceslau, CM; Juby, AG, 2002)
"Osteoporosis is a disease characterized by low bone mineral density (BMD) and up to 80% of its variance is under genetic control."( Adami, S; Braga, V; Gatti, D; Malerba, G; Mirandola, S; Mottes, M; Rossini, M; Sangalli, A; Zamboni, M, 2002)
"Osteoporosis is the most common human bone disease."( Vered, I; Werner, P, 2002)
"Osteoporosis is one of the leading causes of morbidity and mortality in the elderly population."( Boyanov, M; Popivanov, P, 2002)
"Osteoporosis is a common and serious complication of solid organ transplantation."( Alexander, GJ; Compston, JE; Garrahan, NJ; Ninkovic, M; Vedi, S, 2002)
"Osteoporosis is a systemic skeletal disorder leading to decreased bone mineralisation and a propensity for fracture."( Buchman, A; DeSantis, A, 2002)
"Osteoporosis is a major and growing problem for older women and men in western society."( Doggrell, SA, 2002)
"We conclude that osteoporosis is a very common condition in patients with end-stage pulmonary disease, independent of the underlying diagnosis."( Boehler, A; Russi, EW; Schmid, C; Seifert, B; Speich, R; Tschopp, O; Weder, W, 2002)
"Osteoporosis is a common disease in the elderly, and the fractures that result from this disorder affect 40 % of women and 14 % of men over the age of 50 years."( Eastell, R; Lambert, H, 2002)
"Osteoporosis is almost universal in very old age, and is a major cause of morbidity and mortality in the elderly of both sexes."( Fraser, WD; Jackson, MJ; Lowe, NM, 2002)
"Osteoporosis is a common disease characterized by decreased bone mass and increased fracture risk in postmenopausal women and the elderly."( Flik, KR; Gardner, MJ; Lane, JM; Mooar, P, 2002)
"In Crohn's disease, osteoporosis is frequently found."( Corstens, FH; de Jong, DJ; Mannaerts, L; Naber, AH; van Rossum, LG, 2002)
"Osteoporosis is a chronic disease that affects a large number of both men and women and is characterized by a decrease in bone mass, as well as weakened bones."( Rotella, DP, 2002)
"Secondary osteoporosis is a feature of rheumatoid arthritis (RA)."( Alí, I; Dílek, K; Göksal, K; Güner, T; Hüseyin, T, 2002)
"Osteoporosis is a disease manifested in drastic bone loss resulting in osteopenia and high risk for fractures."( Bex, FJ; Bodine, PV; Borella, LE; Gazit, D; Kelly, P; Kharode, YP; Komm, BS; Moutsatsos, IK; Turgeman, G; Zhou, S; Zilberman, Y, 2002)
"Osteoporosis is an important complication of androgen deprivation therapy (ADT)."( Smith, MR, 2002)
"Osteoporosis is characterised by low bone mass and microarchitectural deterioration of bone tissue, leading to enhanced bone fragility and consequent increase in fracture risk."( Francis, RM; Tuck, SP, 2002)
"Osteoporosis is a rare but potentially severe complication under high-dose, long-term unfractionated heparin therapy."( Handschin, AE; Kock, HJ, 2002)
"Periarticular osteoporosis is an early finding in the hands of patients with rheumatoid arthritis (RA), due to release of bone resorbing cytokines from the inflamed synovium."( Adams, J; Bruce, IN; Harrison, BJ; Herrick, AL; Hutchinson, CE, 2002)
"Osteoporosis is a major clinical problem in older women and men."( Deal, C; Srivastava, M, 2002)
"All aspects of osteoporosis care and its fracture complications - including classification, diagnosis, management and methods for screening, as well as prevention and reducing fracture risk - were reviewed, revised as required and expressed as a set of recommendations."( Brown, JP; Josse, RG, 2002)
"Osteoporosis is a common health problem, especially in the elderly and in women after menopause."( Akşen, F; Düz, MZ; Kaya, A; Mustafa, D; Sert, C, 2002)
"Osteoporosis is a major problem of health care delivery services, both in the developed and developing countries."( Pande, KC, 2002)
"Osteoporosis is a debilitating disease that affects many older people."( Prentice, A, 2002)
"Osteoporosis is a growing global problem."( Liebman, M; Weaver, CM, 2002)
"The concept that osteoporosis is a disease characterized exclusively to a reduction in bone density, now leaves room for consideration that corresponds with the concepts of quantitative and quality elements."( Coaccioli, S; Di Cato, L; Ponteggia, F; Ponteggia, M; Puxeddu, A, 2002)
"Osteoporosis is a complication of androgen deprivation therapy in men with prostate carcinoma."( Smith, MR, 2003)
"Osteoporosis is a major cause of morbidity in liver transplant recipients and is associated with multiple factors."( Baruch, Y; Ish-Shalom, S; Kramsky, R; Raz, B; Segal, E; Tamir, A, 2003)
"Osteoporosis is a significant problem in women and men."( Moyad, MA, 2002)
"Osteoporosis is characterized by reduced bone density and strength."( Deavall, DG; Moggs, JG; Orphanides, G, 2003)
"Osteoporosis is a very prevalent complication of anorexia nervosa."( Mehler, PS, 2003)
"Osteoporosis is associated with increased risk of fractures at most skeletal sites."( Sohen, S, 2003)
"Osteoporosis is a frequent complication in Crohn's disease."( Adler, G; Boehm, BO; Hofbauer, LC; Klaus, J; Kratzer, W; Mason, R; Reinshagen, M; Steinkamp, M; von Tirpitz, C, 2003)
"Osteoporosis is considered as one of frequent diseases developing in menopausal women and old men."( Kozłowska-Wojciechowska, M; Makarewicz-Wujec, M; Nowicka, G, 2002)
"Osteoporosis is a silent epidemic in the world today."( Alagiakrishnan, K; Hanley, D; Juby, A; Sclater, A; Tymchak, W, 2003)
"Osteoporosis is a common complication of anorexia nervosa (AN)."( Fukuhara, H; Iketani, T; Kiriike, N; Minamikawa, N; Nagao, K; Nagata, T; Shidao, A; Stein, B, 2003)
"Osteoporosis is a very common disorder, which results in an increase in fracture risk."( Christodoulou, C; Cooper, C, 2003)
"Osteoporosis is one of the most common bone-related disorders in the elderly."( Deng, HW; Dvornyk, V; Recker, RR, 2003)
"Osteoporosis is a serious public health concern."( Advani, S; Wimalawansa, SJ, 2003)
"Osteoporosis is a disease of excess bone fragility that results from both the loss of bone mass and trabecular bone microarchitecture, thereby creating a very fragile skeleton."( Breunig, T; Kinney, JH; Kumer, J; Lane, NE; Modin, G; Wronski, T; Yao, W, 2003)
"Osteoporosis is a well-defined health risk in cystic fibrosis (CF) patients due to many factors."( Aris, RM; Backlund, DC; Blackwood, AD; Brown, SA; Caminiti, MJ; Hensler, MB; Lark, RK; Lester, GE; Ontjes, DA, 2003)
"Osteoporosis is defined as a bone mineral density (BMD) value evaluated by dual-energy X-linked absorptiometry of the lumbar spine of a z score of 2."( Godbole, M; Gulati, K; Gulati, S; Singh, U; Srivastava, A, 2003)
"Osteoporosis is a common complication of untreated male hypogonadism."( Kanumakala, S; Pua, J; Zacharin, MR, 2003)
"Osteoporosis is an important and preventable adverse effect of androgen deprivation therapy for prostate cancer."( Smith, MR, 2003)
"Osteoporosis is a frequent complication after renal transplantation."( Gutierrez, A; Moreno, A; Oppenheimer, F; Torregrosa, JV; Vidal, S, 2003)
"Osteoporosis is a frequent complication in the course of various gastrointestinal disorders."( Reinshagen, M; von Tirpitz, C, 2003)
"Osteoporosis is the main cause of bone fragility in this client group and it is commonly associated with postmenopausal women, although other forms exist."( Unsworth, J, 2003)
"Osteoporosis is a disease that is strongly genetically determined and polymorphisms present in a range of candidate genes may be involved."( Devine, A; Dhaliwal, SS; Dick, IM; Li, S; Prince, RL, 2003)
"Osteoporosis is characterized by a decrease in bone mass as well as a deterioration of the bone architecture resulting in an increased risk of fracture."( Lakatos, P; Takács, I, 2003)
"Male osteoporosis is an increasingly important health problem."( Campagna, S; Dal Canto, N; Franci, B; Gennari, C; Gennari, L; Gonnelli, S; Lucani, B; Martini, G; Merlotti, D; Nuti, R; Valenti, R, 2003)
"Osteoporosis is a systemic disease in which the skeletal condition is characterized by a decreased mass of normally mineralized bone."( Bianchi, AE; Sanfilippo, F, 2003)
"Male osteoporosis is an important disease, with 25-30% of all hip fractures occurring in men."( Drake, WM; Kendler, DL; Orwoll, ES; Rosen, CJ, 2003)
"Hypertension and osteoporosis are characteristic clinical features in patients with Cushing's syndrome or in those on glucocorticoid (GC) treatment."( Ferrari, P, 2003)
"Osteoporosis is an adverse effect of prednisolone therapy, although no study has been conducted on myasthenia gravis patients receiving high-dose prednisolone."( Araki, Y; Hayashi, N; Konno, S; Nakazato, A; Nemoto, H; Nomoto, N; Sugimoto, H; Wakata, N, 2004)
"Acute osteoporosis is one such effect, and a reproducible osteoporosis model has been established through the administration of the immunosuppressant drug FK506 in rats."( Fukunaga, J; Ishiwari, Y; Kirino, S; Lee, YJ; Mizukawa, N; Nagai, N; Sawaki, K; Sugahara, T; Takagi, S; Tsujigiwa, H; Ueno, T; Yamaai, T; Yamachika, E, 2004)
"Senile osteoporosis is the endpoint of a continuum that starts after the third decade of life when peak bone mass is attained and then is followed by a progressive and irreversible decline in bone mass."( Duque, G; Kremer, R; Macoritto, M, 2004)
"Osteoporosis is common, asymptomatic and usually undetected until a fracture occurs."( Braddon, J; Phillips, P, 2004)
"Osteoporosis is a preventable disease that affects millions of Americans, particularly older women."( Busen, NH, 2004)
"Osteoporosis is a major public health problem with an increase of its prevalence with age and growing consequences because of the increase of life expectancy."( Bonjour, JP; Chevalley, T; Rizzoli, R, 2004)
"Osteoporosis is increasingly recognized as a major source of morbidity following renal transplantation."( Cassidy, MJ; Godber, IM; Hosking, DJ; Porter, CJ; Roe, SD, 2005)
"Osteopenia and osteoporosis are common in male transplant recipients, and the hip and radius are the most severely affected sites."( Cassidy, MJ; Godber, IM; Hosking, DJ; Porter, CJ; Roe, SD, 2005)
"Osteoporosis is a decrease in bone mineral density (BMD) that predisposes individuals to fractures."( Campbell, JR; Novotny, L; Puzas, JE; Rosier, RN, 2004)
"Osteoporosis is a cause of considerable morbidity and mortality in men and women."( Fish, SA; Kirk, D, 2004)
"Osteoporosis is a significant comorbidity in SLE."( Fortin, PJ; Gladman, DD; Ibanez, D; Pineau, CA; Urowitz, MB, 2004)
"Osteoporosis is characterised by excess bone fragility resulting from bone loss and altered bone microarchitecture."( Fromigué, O; Marie, PJ; Modrowski, D, 2004)
"Periarticular osteoporosis is one of the first radiological signs of rheumatoid arthritis (RA)."( Black, AJ; Mackenzie, LM; Reid, DM; Stewart, A, 2004)
"Osteoporosis is characterized by a decrease in bone mass and a change in bone microarchitecture."( Alcalay, M; Bontoux, D; Debiais, F; Deplas, A; Thomas, P, 2004)
"Osteoporosis is a common metabolic disease characterized by low bone mass and microarchitectural deterioration of bone tissue."( Bernard, A; Bo, M; Jin, T; Kong, Q; Nordberg, G; Wang, H; Ye, T; Zhu, G, 2004)
"Osteoporosis is characterized by reduced bone mass, abnormal bone architecture and increased fracture risk."( Gámez, R; González, J; Más, R; Mendoza, N; Mendoza, S; Noa, M, 2004)
"Because osteoporosis is a type of pathology very often encountered in implanted patients and can be studied with in vitro models, the purpose of the present study was to evaluate P558 in vitro through comparison of normal (nOB) with osteopenic (oOB) bone-derived primary rat osteoblasts."( Bernauer, J; Borsari, V; Chiesa, R; Chiusoli, L; Cigada, A; Fini, M; Giardino, R; Giavaresi, G; Lenger, H; Rimondini, L; Torricelli, P, 2004)
"Osteoporosis is characterized by a decreased bone mass and an increased bone fragility and susceptibility to fracture."( Anderson, M; Dreinhöfer, KE; Féron, JM; Herrera, A; Hube, R; Johnell, O; Lidgren, L; Miles, K; Simpson, H; Tarantino, U; Wallace, WA, 2005)
"Osteoporosis is one major health condition that contributes to excess morbidity and mortality in women after menopause."( Mirza, FS; Prestwood, KM, 2004)
"Osteoporosis is often first recognized at the time of a low-trauma fracture."( Clapham, S; Eisman, J; Kehoe, L, 2004)
"Although osteoporosis is a relatively common complication after allogeneic stem cell transplantation, the role of bisphosphonates in its management has not yet been completely established."( Colao, A; Lombardi, G; Ricci, P; Rotoli, B; Selleri, C; Serio, B; Tauchmanovà, L, 2005)
"Osteoporosis is still an important health problem in modern societies."( Brodowska, A, 2003)
"Osteoporosis is a common but neglected problem in India."( Handa, R, 2004)
"Osteoporosis is among the top 3 medical conditions that are associated with greatest morbidity and reduction of quality of life of Hong Kong elderly subjects."( Kung, AW, 2004)
"Osteoporosis is the most important metabolic disease leading to fracture and high mortality morbidity rates."( Alexandre, N; Fadi, H; Georges, F; Ghassan, M; Joseph, H; Joseph, W; Marie Hélène, GY, 2004)
"Steroid-induced osteoporosis is the most common form of osteoporosis in the dermatological diseases, but there have been only few data concerning the treatment based on clinical evidences."( Okada, N, 2004)
"Osteoporosis is thought to be one possible side-effect of oral anticoagulant therapy, especially after long-term treatment."( Kemkes-Matthes, B; Liebig, S; Nees, M; Stracke, H, 2004)
"Although osteoporosis is a major health concern for our growing population of the elderly, there continues to be a need for well-designed clinical and animal studies on the link between dietary magnesium (Mg) intake and osteoporosis."( Gruber, HE; Rude, RK, 2004)
"If osteoporosis is linked with vitamin A (Vit A) A consumption, millions of people could be affected."( Crandall, C, 2004)
"Osteoporosis is a major and growing healthcare concern as the population ages."( Chen, W; Diao, W; Ji, J; Liu, J; Tang, J, 2005)
"Osteoporosis is the main cause of fracures in post-menopausal women, a common occurrence worldwide, giving rise to disability and a high cost to health services."( Kazantzis, G, 2004)
"Osteoporosis is increasingly recognised in men [3-11]."( Diamond, TH, 2005)
"Treatment of osteoporosis is often inadequate."( Arnason, JA; Pickney, CS, 2005)
"Osteopenia and osteoporosis are frequent complications of HIV infection and/or its treatment."( Claxton, SA; Hoffmann, ME; Mondy, K; Powderly, WG; Royal, M; Stoneman, JS; Tebas, P; Yarasheski, KH, 2005)
"Regional migratory osteoporosis is an uncommon self-limiting disease characterized by an arthralgia which migrates between the weight-bearing joints of the lower limb."( Barker, T; Becker, E; Donell, ST; Lobo-Mueller, EM; Marshall, TJ; Toms, AP, 2005)
"Osteoporosis is a leading public health threat affecting approximately 44 million people in the United States."( Gonyeau, MJ, 2005)
"Osteoporosis is associated with increased bone resorption together with a decrease in bone formation."( Benito-Ruiz, P; Blanch-Rubió, J; Carbonell-Abelló, J; Ciria-Recasens, M; Mariñoso, ML; Pérez-Edo, L; Serrano, S, 2005)
"Osteoporosis is the most frequent adverse effect observed during glucocorticoids therapy."( Soen, S, 2005)
"Osteoporosis is a chronic condition chiefly affecting postmenopausal women, in whom the skeleton loses a significant percentage of its mineralized mass and mechanical resiliency, thereby becoming prone to fracture."( Fan, Y; He, W; Liu, J; Peng, X; Shi, F; Wang, H; Wang, S; Xiong, L, 2005)
"Osteoporosis is a common complication of ADT."( Anastasi, G; Franchina, F; Frisina, N; Galì, A; Gaudio, A; Magno, C; Maisano, D; Melloni, D; Morabito, N, 2005)
"Osteoporosis is now recognized as an increasingly prevalent disorder throughout the world."( Kleerekoper, M, 2005)
"Osteoporosis is a complex multi-factorial disease where environment, diet and genetics play a role in determining susceptibility."( Frampton, CM; George, PM; Gilchrist, NL; Morrison, NA; Tilyard, MW; Vaughan, T, 2005)
"If patients with osteoporosis are being diagnosed and effective treatments used with increasing frequency in the population, rates of hip and wrist fractures will remain stable or possibly decrease."( Adachi, JD; Hawker, G; Jaakkimainen, L; Jaglal, SB; Kreder, H; Mamdani, M; Weller, I, 2005)
"Osteoporosis is a common concomitant disease in patients with rheumatic diseases on glucocorticoid (GC) therapy."( Bohl, N; Burmester, GR; Buttgereit, F; Loddenkemper, K; Perka, C, 2006)
"Osteoporosis is a metabolic bone disorder, leading to bone fragility and fracture."( Fogelman, I, 2005)
"Osteoporosis is known to impair the process of implant osseointegration."( Bauss, F; Eberhardt, C; Kurth, AH; Müller, S; Schwarz, M; Steinacker, M, 2005)
"Osteoporosis is common in adults who undergo cardiac transplantation."( Addesso, V; Addonizio, LJ; Cohen, A; Gao, P; Lamour, JM; Shane, E; Staron, RB, 2005)
"Osteoporosis is common in these patients, particularly at the one-third radius, a site sensitive to the catabolic effects of sustained excessive PTH secretion."( Addesso, V; Addonizio, LJ; Cohen, A; Gao, P; Lamour, JM; Shane, E; Staron, RB, 2005)
"Osteoporosis is a common disorder, especially among elderly post-menopausal women."( Bifulco, G; Cascella, T; Colao, A; Lombardi, G; Musella, T; Nappi, C; Orio, F; Palomba, S; Tauchmanova, L, 2005)
"Osteoporosis is one of the major health problems in our modern world."( Denhardt, DT; Ezura, Y; Karsenty, G; Kondo, H; Nakashima, K; Nifuji, A; Noda, M; Rittling, SR; Takeda, S, 2005)
"Although osteoporosis is a worldwide health problem, there are many differences in ethnic groups regarding disease morbidity and drug treatment efficacy."( Massart, F, 2005)
"Osteoporosis is prevalent in men with an estimated one in eight men older than 50 years suffering from osteoporotic fracture, and a higher mortality rate after fracture among men compared with women."( Dorst, A; Faber, H; Farahmand, P; Ringe, JD, 2006)
"Osteoporosis is a common problem in orthopedic surgery."( Hohlweg-Majert, B; Pfeiffer, BM; Schmelzeisen, R; Schneider, E, 2006)
"In men, osteoporosis is a prevalent problem that is under-recognized and undertreated."( Amin, S, 2003)
"Clinically, osteoporosis is diagnosed using dual energy x-ray absorptiometry."( Brennan, O; Kennedy, OD; Lee, TC; O'Brien, FJ, 2005)
"Osteoporosis is one of the most important problems in developed societies."( Herman, ZS; Krysiak, R; Labuzek, K; Okopień, B, 2005)
"Osteoporosis is one of the most serious complications of corticosteroid treatment."( Iwamoto, J; Sato, Y; Takeda, T, 2005)
"Osteopenia and osteoporosis are common complications of chronic liver disease (CLD)."( Graziadei, I; Habior, A; Kaser, A; Kaser, S; Millonig, G; Moschen, AR; Mühllechner, P; Stadlmann, S; Tilg, H; Vogel, W, 2005)
"Osteoporosis is a common condition in men affecting approximately 2 million males in the US."( Kamel, HK, 2005)
"Osteoporosis is frequent in AS and high disease activity is associated with an alteration in vitamin D metabolites and increased levels of bone resorption in active AS."( Lange, U; Müller-Ladner, U; Schmidt, KL; Strunk, J; Teichmann, J, 2005)
"Osteoporosis is a common complication of ankylosing spondylitis (AS)."( Aydin, T; Demir, SE; Karacan, I; Sahin, Z, 2005)
"Osteoporosis is characterized by low bone mass and increased susceptibility to fracture."( Marie, PJ, 2005)
"Osteoporosis is induced by glucocorticoids in rats during a 12-week period."( Ajduković, Z; Dordević, LJ; Ignjatović, N; Mihailović, D; Najman, S; Petrović, D; Savić, V; Uskoković, D, 2005)
"Osteoporosis is a serious and common condition with very high associated healthcare costs."( Jack, D, 2005)
"Osteoporosis is one of the most important problems in developed societies."( Herman, ZS; Krysiak, R; Labuzek, K; Okopień, B, 2005)
"Osteoporosis is a widespread problem, which frequently has devastating health consequences through its association with fragility fractures."( Herrmann, M; Herrmann, W; Widmann, T, 2005)
"Osteoporosis is a known consequence of spinal cord injury (SCI) and occurs in almost every SCI patient."( Dai, LY; Jiang, LS; Jiang, SD, 2006)
"Osteoporosis is recognized as a common medical complication of anorexia nervosa (AN)."( Kojima, S; Muranaga, T; Nagai, N; Nakahara, T; Naruo, T; Nozoe, S; Tanaka, M, 2006)
"Osteoporosis is a common and preventable disorder of the older adult skeleton that predisposes an individual to an increased risk of fracture, a major cause of disability in older adults."( Birge, SJ; Wilkins, CH, 2005)
"Drug treatment of osteoporosis is based on the knowledge of mechanisms of bone turnover and the manipulation of the cellular components of bone turnover in terms of recruitment, activation and apoptosis of the cells involved."( Geusens, P; Reid, D, 2005)
"Secondary osteoporosis is common among patients being evaluated for osteoporosis."( Kelman, A; Lane, NE, 2005)
"Osteoporosis is a disorder in which loss of bone strength leads to fragility fractures."( Raisz, LG, 2005)
"Osteoporosis is the most common bone disease, affecting millions of people worldwide and leading to significant morbidity and high expenditure."( Jadhav, SB; Jain, GK, 2006)
"While osteoporosis is increasingly identified and treated with effective medications, calcium is being neglected as a component of osteoporosis management."( Drieling, RL; Johns, R; Ma, J; Stafford, RS, 2005)
"Osteoporosis is a long-term complication of allogeneic stem cell transplantation (SCT)."( Kananen, K; Laitinen, K; Ruutu, T; Välimäki, MJ; Volin, L, 2006)
"Osteoporosis is a major health problem characterized by compromised bone strength predisposing patients to an increased risk of fracture."( Atik, OS; Eksioglu, F; Satana, T; Uslu, MM, 2006)
"Osteoporosis is a common, multifactorial cause of morbidity in patients with beta-thalassemia."( Angelopoulos, NG; Goula, A; Ioannis, P; Kaltsas, D; Kaltzidou, V; Katounda, E; Rombopoulos, G; Tolis, G, 2006)
"Osteopenia and osteoporosis are well known complications in beta thalassemia major (TM) patients."( Kosaryan, M; Shahi, VK; Zadeh, MF, 2004)
"Osteoporosis is a systemic skeletal disease characterized by low bone mass and the microarchitectural deterioration of bone tissue."( Kobayashi, Y; Takahashi, N, 2006)
"Osteoporosis is a metabolic bone disease characterized by reduced bone mass and deterioration of bone microarchitecture."( Anastassopoulos, G; Christopoulou, GE; Karamanos, NK; Panagiotopoulos, E; Panteliou, SD; Papadaki, E; Stavropoulou, A, 2006)
"Osteoporosis is a major problem in contemporary society."( Celik, A; Ciçek, HK; Kepkep, N; Meram, I; Yilmaz, N, 2006)
"Osteoporosis is a skeletal chronic multifactorial disease characterised by abnormal low bone mass and microarchitectural deterioration of bone tissue."( Brandi, ML; Carbonell Sala, S; Del Monte, F; Falchetti, A; Franceschelli, F; Marini, F; Masi, L, 2005)
"Osteoporosis is the most prevalent metabolic bone disease among developed countries."( De Paola, V; Gennari, L; Martini, G; Merlotti, D; Nuti, R; Valleggi, F, 2005)
"Osteoporosis is prevalent in hemodialysis patients."( Barreto, DV; Barreto, FC; Canziani, ME; Carvalho, AB; Draibe, SA; Jorgetti, V; Moyses, RM; Neves, CL, 2006)
"Osteoporosis is common in Thai renal allograft recipients, particularly of the lumbar vertebrae."( Avihingsanon, Y; Eiam-Ong, S; Kanjanabuch, T; Kingpetch, K; Praditpornsilpa, K; Suwanwalaikorn, S; Techawathanawanna, N; Tungsanga, K, 2005)
"Secondary causes of osteoporosis are found in a proportion of patients."( Barth, JH; Orme, SM; Rajeswaran, C; Spencer, J, 2007)
"Osteoporosis is the most common bone disease in humans and affects both men and women."( Clarke, BL; Mauck, KF, 2006)
"Fracture healing in osteoporosis is delayed, with reduced callus formation and impaired biomechanical properties of newly formed bone leading to high risk of fixation failure."( Adamaszek, S; Baltzer, AW; Egermann, M; Evans, C; Lill, CA; Robbins, P; Schneider, E, 2006)
"Osteoporosis is a major public health problem, associated with substantial morbidity and socio-economic burden."( Kour, A; Kumar, D; Mahajan, A; Sharma, S; Tandon, VR, 2006)
"Osteoporosis is a serious public health issue."( Cooper, C; Sambrook, P, 2006)
"Osteoporosis is an important cause of morbidity in beta-thalassemia patients."( Azar, ST; Habr, D; Inati, A; Koussa, S; Mahfouz, RA; Otrock, ZK; Shamseddeen, WA; Taher, AT, 2006)
"Bone loss and osteoporosis are major public health problems in the elderly."( McDonald, JM; Yeo, H; Zayzafoon, M, 2006)
"Osteoporosis is a disease of bone metabolic disorder, the incidence of which increases sharply in old people."( He, X; Li, P; Liu, Y; Ma, QJ; Peng, YF; Yang, XL; Zhang, YH; Zhong, H, 2006)
"Osteoporosis is characterized by low bone mass and by changes in the microarchitecture of the bone."( Neumann, E, 2006)
"Osteoporosis is a common complication in patients with end-stage liver disease and after orthotopic liver transplantation (LT), with resulting increasing fracture rate."( Fiore, CE; Giostra, E; Mentha, G; Pennisi, P; Rizzoli, R; Trombetti, A, 2007)
"However, because osteoporosis is a complex and heterogeneous disease with different pathogenetic factors, defining the role of the different factors in its development is important in formulating a more selective approach to therapy."( Odvina, CV, 2006)
"Osteoporosis is a skeletal disease characterized by increased risk of fracture due to reduced bone strength."( Inoue, D; Matsumoto, T, 2006)
"Osteoporosis is associated with low intake of calcium and other nutrients."( Hirota, K; Hirota, T, 2006)
"Osteoporosis is a common disease with a strong genetic component characterized by reduced bone mass and increased risk of fragility fractures."( de Crombrugghe, B; Ralston, SH, 2006)
"In adults, osteoporosis is associated with polymorphisms of vitamin D receptor (VDR), estrogen receptor (ER), and collagen Ialpha1 (COLIA1) genes."( Czakó, M; Ertl, T; Funke, S; Kosztolányi, G; Morava, E; Vida, G, 2006)
"Osteoporosis is a skeletal disorder characterized by low bone mass and deterioration of bone microarchitecture resulting in bone fragility, which increases the risk of fracture."( Bauss, F; Dempster, DW, 2007)
"Osteoporosis is a frequent disease among the elderly and has major consequences in terms of mortality, morbidity and cost."( Duque, G; Retornaz, F, 2006)
"Osteoporosis is a known complication of spinal cord injury (SCI), but its mechanism remains unknown."( Dai, LY; Jiang, LS; Jiang, SD, 2006)
"Osteoporosis is a major healthcare problem around the world and its importance lies in the fractures that result."( Pande, KC; Pande, SK; Veeraji, E, 2006)
"Osteoporosis is the most frequent adverse effect of glucocorticoids."( Soen, S, 2006)
"Osteoporosis is defined as "a systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue with a consequent increase in bone fragility and susceptibility to fracture"."( Binkley, N, 2006)
"Osteoporosis is associated with decreased bone strength as a consequence of decreased bone density and altered quality."( Lane, JM; Raphael, B; Serota, AC, 2006)
"Osteoporosis is a major public health problem that is characterized by microarchitectural deterioration, low bone mass, and increased risk of fractures."( Kolatkar, NS; LeBoff, MS; Mulder, JE, 2006)
"Importantly, osteoporosis is a major cause of morbidity and mortality in the elderly population."( Nakamura, T, 2007)
"Osteoporosis is known to complicate outcomes after lung transplantation (Tx)."( Baz, MA; Braith, RW; Casey, DP; Conner, JA; Fulton, MN; Howe, KS; Lisor, CF, 2007)
"Osteoporosis is a major health threat."( Li, A; Li, Y; Nanes, MS; Strait, K; Weitzmann, MN; Zhang, H, 2007)
"Osteoporosis is recognized as a major concern among menopausal women and the elderly."( Kang, GJ; Kang, HK; Lee, HJ; Yoo, ES; Yoon, WJ, 2007)
"Osteoporosis is a serious public health issue, affecting up to 1 in 2 women and 1 in 5 men over the age of 50 years."( Keen, R, 2007)
"Osteoporosis is one of the most widespread and destructive bone diseases in our modern world."( Denhardt, DT; Ezura, Y; Kato, N; Kitahara, K; Kurosawa, H; Nakashima, K; Noda, M; Rittling, SR, 2007)
"Osteoporosis is a systemic disease of the bones with increasing incidence in the elderly."( Lümmen, G; Rübben, H; Schneider, T; Sperling, H, 2007)
"Transient migratory osteoporosis is characterized by the acute onset of migratory pain at weight-bearing joints."( Carty, S; Herdman, G; Srinivasan, U; Williams, F, 2007)
"Osteoporosis is a systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility."( Potocki, K, 2006)
"Osteoporosis is chronic bone disorder that require persistent treatment."( Babić-Naglic, D; Grazio, S, 2006)
"Osteoporosis is a serious public health concern."( Horvath, PJ; McCann, SE; McLeod, KM; Wactawski-Wende, J, 2007)
"Osteoporosis is a reduction in bone mass sufficient to increase the risk of fracture."( Auinger, P; Campbell, JR, 2007)
"Osteoporosis is a well-known complication of Crohn's disease (CD)."( Blázovits, A; Herszényi, L; Lakatos, P; Miheller, P; Muzes, G; Rácz, K; Tulassay, Z, 2007)
"Secondary osteoporosis is caused by various non-physiological factors."( Lange, U; Müller-Ladner, U, 2007)
"Osteoporosis is common in patients with inflammatory bowel disease (IBD)."( Abitbol, V; Allez, M; Bouhnik, Y; Briot, K; Charachon, A; Chaussade, S; Coffin, B; Lamarque, D; Roux, C; Roy, C; Seksik, P, 2007)
"Osteopenia and osteoporosis are common in HIV-1-infected individuals and represent a challenge in clinical and therapeutic management."( Borderi, M; Caudarella, R; Chiodo, F; Cicola, R; De Crignis, E; Gibellini, D; Re, MC; Vescini, F, 2007)
"Osteoporosis is a multifactorial chronic disease that may become even more prevalent and more of a public health problem in the decades to come."( Boscaro, M; Fiscaletti, P; Francucci, CM; Rilli, S, 2007)
"Osteoporosis is a common disease that makes bones prone to fracture and can affect both men and women."( Chen, XG; Li, J; Liu, Y; Yu, KQ; Zhang, J; Zhao, Y, 2007)
"Osteoporosis is a common adverse reaction induced by glucocorticoid treatment."( Ichimura, A; Iwata, H; Nakajima, T; Ochiai, H; Takagi, H; Toriyama, T; Tsuchiya, H; Yamada, S, 2007)
"Osteoporosis is a common and severe condition in elderly men, which is poorly characterized."( Hofbauer, G; Kneissel, M; Pietschmann, P; Rauner, M; Skalicky, M; Stupphann, D; Viidik, A, 2007)
"Osteoporosis is a severe complication of glucocorticoid treatment."( Bertoldo, F; Dalle Carbonare, L; Fassina, A; Giannini, S; Lo Cascio, V; Realdi, G; Sella, S; Turco, G; Valenti, MT; Zordan, S, 2007)
"Osteoporosis is one of such problem that has been increasingly identified in patients with cancer."( González Macías, J; Olmos Martínez, JM, 2007)
"Osteoporosis is a chronic condition that generally requires long-term therapy for fracture risk reduction to become apparent."( Sambrook, P, 2007)
"However, male osteoporosis is a relatively new phenomenon."( Caffagni, G; Carani, C; Diazzi, C; Madeo, B; Pignatti, E; Rochira, V; Sanguanini, A; Zirilli, L, 2007)
"Osteoporosis is characterized by an increased risk of bone fractures, affecting especially the forearm, vertebrae and hip."( Devlin, H; Horner, K, 2008)
"Osteoporosis is recognized as a major health threat."( Blahos, J, 2007)
"Osteoporosis is a complication of hyperparathyroidism (HPT)."( Alley, RA; Beyer, TD; Chen, EL; Prinz, RA, 2008)
"Osteoporosis is a serious public health issue."( Kariuki, JG; Oyoo, GO, 2007)
"Osteoporosis is a frequent complication in patients with inflammatory bowel disease."( Klaus, J; König, HH; Konnopka, A; Kreck, S; Leidl, R; Matschinger, H; von Tirpitz, C, 2008)
"Osteoporosis is a metabolic bone disease characterized by reduced bone quality and quantity."( Alt, V; Drosse, I; Heiss, C; Hoesel, LM; Horas, U; Meyer, C; Schieker, M; Schnettler, R; Wehr, U; Wenisch, S, 2008)
"Osteoporosis is a potential risk factor affecting implant stability following total joint arthroplasty."( Abu-Ali, S; Fotovati, A; Hayashi, K; Naito, M; Nakamura, Y, 2008)
"The pathogenesis of osteoporosis is multifactorial."( Lanham-New, SA, 2008)
"Osteoporosis is a preventable disease characterized by loss of bone mineral density, progression to diminished skeletal integrity, extensive bone fragility, and an increased risk of fracture."( Lewiecki, EM, 2008)
"Osteoporosis is a common disease in middle-aged and older Americans."( Edwards, BJ; Migliorati, CA, 2008)
"Osteoporosis is diagnosed by the measurement of bone mineral density, which is a highly heritable and multifactorial trait."( Ahmadi, KR; Andrew, T; Arp, P; Deloukas, P; Falchi, M; Gwilliam, R; Hart, D; Hofman, A; Inouye, M; Jhamai, M; Kato, BS; Kumanduri, V; Moorhouse, M; Mullin, BH; Pastinen, TM; Pols, HA; Richards, JB; Rivadeneira, F; Soranzo, N; Spector, TD; Uitterlinden, AG; Valdes, AM; van Meurs, JB; Verlaan, DJ; Whittaker, P; Wilson, SG; Zhai, G; Zhang, F, 2008)
"Osteoporosis is characterized by low bone mass with micro architectural deterioration of bone tissue leading to enhance bone fragility, thus increasing the susceptibility to fracture."( Malhotra, N; Mithal, A, 2008)
"Osteoporosis is a common skeletal disease with a strong genetic component characterized by reduced bone mass and increased risk of fragility fractures."( Brandi, ML; Marcucci, G; Massart, F, 2008)
"The incidence of osteoporosis is increasing worldwide."( Loh, KY; Shong, HK, 2007)
"Osteoporosis is the most prevalent skeletal disorder, characterized by a low bone mineral density (BMD) and bone structural deterioration, leading to bone fragility fractures."( Akiyama, K; Bi, Y; Chen, W; Gronthos, S; Gutkind, S; Le, A; Liu, Y; Miura, Y; Patel, V; Shi, S; Sonoyama, W; Wang, CY; Yamaza, T; Young, M, 2008)
"As osteoporosis is a silent disease, and therapy is required for many months before benefit is realized, strategies to increase bone mineral density (BMD) and improve medication adherence are important aspects of every patient's care plan."( Martens, MG; Shaw, H, 2008)
"Osteoporosis is influenced by iron overload in hemochromatosis."( Fargion, S; Fracanzani, AL; Rossi, V; Sinigaglia, L; Valenti, L; Varenna, M, 2009)
"Osteoporosis is observed in a quarter of unselected patients with HHC, independently of the genetic background, and is associated with ALP, hypogonadism, body weight, and severity of iron overload."( Fargion, S; Fracanzani, AL; Rossi, V; Sinigaglia, L; Valenti, L; Varenna, M, 2009)
"Osteoporosis is a systemic skeletal disorder characterized by low bone mass and microarchitectural deterioration of bone tissue resulting in compromised bone strength and an increased risk of fracture."( Hochberg, MC, 2008)
"The treatment of osteoporosis is largely based around the use of agents that inhibit bone resorption by osteoclasts."( Reid, IR, 2008)
"Osteoporosis is caused by a failure of bone homeostasis, but the precise molecular mechanisms controlling bone homeostasis are largely unknown."( Takeda, S, 2009)
"Osteoporosis is a common condition in men that can have serious clinical consequences."( Dorst, A; Faber, H; Farahmand, P; Ringe, JD, 2009)
"Osteoporosis is a multifactorial disease entailing a high risk to sustain fragility fractures."( Ebert, R; Jakob, F; Seefried, L, 2008)
"Osteoporosis is widely prevalent in India and osteoporotic fractures are a common cause of morbidity and mortality."( Lakhotia, SM, 2008)
"Hypertension and osteoporosis are two major age-related disorders; however, the underlying molecular mechanism for this comorbidity is not known."( Asaba, Y; Fukamizu, A; Fukuhara, R; Fumoto, T; Ikeda, K; Ishida, J; Ito, M; Nimura, Y; Takeshita, S; Watanabe, K, 2009)
"Osteoporosis is a disease of aging associated with bone loss that often occurs without symptoms until microarchitectural deterioration becomes so significant that bone fracture occurs."( Aruoma, OI; Higa, T; Ke, B; Ling, Y; Qiu, W; Xu, Y; Xu, Z, 2009)
"Osteoporosis is common in prostate cancer (CaP) patients both before and after institution of androgen deprivation therapy and is associated with significant morbidity."( Acharya, NC; Agarwal, MM; Khandelwal, N; Kumar, S; Malhotra, S; Mandal, AK; Rana, SV; Singh, SK, 2008)
"Osteoporosis is a major public health problem of older people."( Pepersack, T, 2008)
"Fracture healing in osteoporosis is delayed."( Frosch, KH; Rack, T; Sehmisch, S; Seidlova-Wuttke, D; Stuermer, EK; Stuermer, KM; Tezval, M; Wenda, E; Wuttke, W, 2010)
"Male osteoporosis is increasingly recognized as a major public health issue."( Boonen, S; Delmas, PD; Eusebio, R; Orwoll, ES; Stoner, KJ; Wenderoth, D, 2009)
"Osteoporosis is often treated with bisphosphonates, which reduce fracture risk."( Bouxsein, ML; Brouwers, JE; Rietbergen, Bv; Ruchelsman, M, 2009)
"Osteoporosis is known to impair the process of implant osseointegration."( Chen, J; Du, Z; Xiao, Y; Yan, F, 2009)
"Osteoporosis is a silent disease and becomes clinically significant in the presence of fragility fracture."( Lo, WY, 2008)
"Osteoporosis is a common disorder with significant morbidity and mortality."( Lash, RW; McCort, J; Nicholson, JM; Van Harrison, R; Velez, L, 2009)
"Osteoporosis is a very common disease, which affects aged elderly people."( Gómez de Tejada Romero, MJ; Sosa Henríquez, M, 2009)
"Osteoporosis is a growing health concern as the number of senior adults continues to increase worldwide."( Berry, SD; Colón-Emeric, C; Curtis, JR; Flood, KL; Lyles, KW; Outman, RC; Saag, KG; Tanner, SB; Warriner, AH; Watts, NB, 2009)
"Osteoporosis is a systematic disease characterized by low bone mass and declining bone structure."( Bergert, FW; Conrad, D; Ehrenthal, K; Fessler, J; Gross, J; Gundermann, K; Kluthe, B; Lang Heinrich, W; Liesenfeld, A; Loew, PG; Luther, E; Pchalek, R; Seffrin, J; Sterzing, A; Wolfring, HJ; Zimmermann, U, 2009)
"Male osteoporosis is an important public health issue and remains undertreated."( Chen, JT; Zhong, ZM, 2009)
"Osteoporosis is a metabolic condition that is increasing in prevalence as people live longer."( Collinge, C; Gehrig, LM; Kaufman, J; Lane, JM; O'Connor, MI; Tosi, LL, 2009)
"Osteoporosis is a complex skeletal disorder in which compromised bone strength increases the risk of fragility fractures."( Becker, C, 2008)
"Osteoporosis is a disease in which the density and quality of bone is reduced, leading to an increase in fragility fractures."( Masuda, H; Tanaka, S, 2009)
"Osteoporosis is a classical age-related disease that affects women more often than men."( Kerschan-Schindl, K; Patsch, J; Pietschmann, P; Rauner, M; Sipos, W, 2009)
"Osteoporosis is common in patients with COPD, but its prevalence and progression are not well characterized."( Anderson, JA; Calverley, PMA; Celli, B; Ferguson, GT; Jenkins, CR; Jones, PW; Vestbo, J; Willits, LR; Yates, JC, 2009)
"Osteoporosis is highly prevalent in patients with COPD, irrespective of gender."( Anderson, JA; Calverley, PMA; Celli, B; Ferguson, GT; Jenkins, CR; Jones, PW; Vestbo, J; Willits, LR; Yates, JC, 2009)
"Osteoporosis is common in patients with chronic obstructive pulmonary disease (COPD)."( McDermott, MT; Valdez, C; Voelkel, NF; Vondracek, SF, 2009)
"Post-menopausal osteoporosis is considered to be an inflammatory process, in which numerous pro-inflammatory and T-cell-derived cytokines play a bone-destructive role."( Gaffen, SL; Goswami, J; Hernández-Santos, N; Zuniga, LA, 2009)
"Male osteoporosis is an increasingly important health problem worldwide."( Balaganesh, M; Balasubramanian, K; Ilangovan, R; Queimado, L; Ravi Sankar, B; Sittadjody, S; Sivakumar, R; Srinivasan, N; Srinivasan, S; Subramanian, C; Thompson, DM, 2009)
"Postmenopausal osteoporosis is the most frequent metabolic bone disease; it is characterized by a rapid loss of mineralized bone tissue."( Bhat, KM; Chamallamudi, MR; Dharmavarapu, PK; Kedage, V; Nampurath, GK; Nayak, SR; Potu, BK; Prasad, K; Rao, MS, 2009)
"Osteoporosis is a chronic disease with an enormous impact on health care costs."( Dinges, G, 2009)
"Osteoporosis is associated with the pathogenesis and risk of urolithiasis, which is higher among postmenopausal women (as opposed to premenopausal)."( Hamamoto, S; Hirose, M; Itoh, Y; Kobayashi, T; Kohri, K; Okada, A; Tozawa, K; Yasui, T, 2009)
"In conclusion, osteoporosis is a frequent complication that requires detection and treatment to reduce morbidity."( Ahmadpoor, P; Ghafari, A; Makhdoomi, K; Rahimi, E; Reisi, S; Sepehrvand, N, 2009)
"Osteoporosis is a common complication in thalassemia major (TM)."( Cheng, FW; Chu, Y; Lee, V; Leung, TF; Leung, WK; Li, CK; Shing, MM, 2009)
"Osteoporosis is common problem accounting for 2 million fractures per year in the United States at a cost of over $17 billion dollars."( Gruber, HE; Rude, RK; Singer, FR, 2009)
"Osteoporosis is a systemic disease of the skeleton, characterized by reduction of bone mass and concurrent deterioration of bone structure."( Ryšavá, L; Stránský, M, 2009)
"Osteoporosis is characterised by low bone mass and structural deterioration of bone tissue."( Akdeniz, N; Akpolat, V; Celik, MS; Celik, Y; Ozerdem, MS, 2009)
"Osteoporosis is accompanied by predominantly metaphyseal fractures with a delayed and qualitatively reduced healing process."( Hoerster, AK; Kolios, L; Malcherek, MC; Rack, T; Sehmisch, S; Seidlova-Wuttke, D; Stuermer, EK; Stuermer, KM; Tezval, M; Wuttke, W, 2010)
"Osteoporosis is a widespread problem afflicting millions of people."( Persson, JL; Wegiel, B, 2010)
"Primary osteoporosis is usually a result of reduced bone mineral density as a consequence of natural aging."( Hebl, S; Huston, AJ; Ling, MN; Morrow, GR; Mustian, KM; Palesh, OG; Peppone, LJ; Purnell, JQ; Reid, ME; Rosier, RN, 2010)
"Osteoporosis is a major public health burden through associated fragility fractures."( Cooper, C; Dennison, EM; Earl, S; Harvey, NC; Winsloe, C, 2009)
"Osteoporosis is a worldwide major public health problem, defined as "a systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue with a consequent increase in bone fragility and susceptibility to fractures"."( Aliberti, G; Pisani, D; Rocchietti March, M, 2009)
"Osteoporosis is a common complication in chronic cholestasis."( Alvarez, L; Combalia, A; de Osaba, MJ; Enjuanes, A; Gonzalez, B; Guañabens, N; Martinez-Ferrer, A; Monegal, A; Parés, A; Peris, P; Ruiz-Gaspà, S, 2010)
"Osteoporosis is the most prevalent bone complication in beta-thalassemic patients despite regular transfusions and iron chelation therapy."( Abo-Salem, OM; El-Edel, RH; El-Nemr, FM; Ghonaim, MM, 2010)
"Osteoporosis is characterized by low bone mineral density (BMD), resulting in increasing susceptibility to bone fractures."( Blanch-Rubió, J; Carbonell-Abelló, J; Ciria-Recasens, M; Garcia-Giralt, N; Monfort, J; Monllau, JC; Nogués, X; Pérez-Edo, L; Ruiz-Gaspà, S; Tío, L, 2010)
"Osteoporosis is characterized by low bone mineral density and structural deterioration of bone tissue, leading to an increased risk of fractures."( Chen, JM; Férec, C; Hou, SX; Li, MM; Li, WF; Yu, B, 2010)
"Osteoporosis is a serious health problem worldwide and leads to a significant burden on society."( Chen, F; Chen, J; Yun, F; Zhang, J, 2010)
"Osteoporosis is a systemic disease, which is characterized by reduced bone mass and microarchitectural deterioration of the bone tissue, resulting in an increased risk of fracture."( Mihaljević, I; Mudri, D; Smolić, M; Smolić, R; Tucak-Zorić, S, 2009)
"Osteoporosis is a disease of low bone mass most often caused by an increase in bone resorption that is not sufficiently compensated for by a corresponding increase in bone formation."( Balaji, S; Balapure, AK; Ducy, P; Gershon, MD; Guo, XE; Karsenty, G; Li, Z; Liu, XS; Lu, X; Mann, JJ; Medhamurthy, R; Suresh, PS; Vidal, M; Yadav, VK, 2010)
"Osteoporosis is a bone disease that can reduce both bone mass and bone strength."( Chou, P; Renn, JH; Yang, NP, 2010)
"Osteoporosis is a problem after transplantation."( Bjortuft, O; Bollerslev, J; Forli, L; Gadeholt, G; Godang, K; Isaksen, GA; Kvamsdal, KE; Pripp, AH; Simonsen, S, 2010)
"Osteoporosis is a metabolic disease of the bone characterized by reduced bone mass and microstructural deterioration of bone tissue with a consequent increase in bone fragility and risk of vertebral collapse."( Crestani, F; Piva, B; Shaladi, AM; Tartari, S, 2009)
"Osteoporosis is a major cause of low-energy hip fractures."( Abrahamsen, B; Eiken, PA, 2010)
"Osteoporosis is a common cause of disability and death in elderly men and women."( Duncan, EL; Gunanti, I; Hollingworth, SA; Nissen, LM, 2010)
"Osteoporosis is of concern in breast cancer patients who are undergoing chemotherapy."( Cheung, MN; Chow, LW; Jin, LJ; Loo, WT; Wang, M, 2010)
"The burden of osteoporosis is on the rise and glucocorticoids are one of the leading causes of drug-induced osteoporosis."( Gera, C; Vij, AS, 2009)
"Male osteoporosis is not the epidemic problem that female osteoporosis is; however, the National Osteoporosis Foundation estimates that over 14 million American men have osteoporosis or low bone mass, and approximately 25% to 30% of all hip fractures occur in male individuals who incur greater morbidity and mortality than their female counterparts."( Maricic, M, 2010)
"Involutional osteoporosis is one of common diseases related to ageing."( Takeuchi, Y, 2010)
"Osteoporosis is known to increase in prevalence with age."( Kawate, H; Takayanagi, R, 2010)
"Although osteoporosis is increasingly shown to occur in a considerable proportion of men, data on risk factors for male osteoporosis are limited."( Bae, SJ; Choe, JW; Kim, BJ; Kim, GS; Kim, HK; Kim, HY; Koh, JM; Lee, SH, 2010)
"Osteoporosis is a systemic skeletal disease responsible for the high incidence of fractures in older subjects, particularly in postmenopausal women."( Cooper, C, 2010)
"Osteoporosis is listed by the WHO among the ten most frequent and socio-economically important, chronic diseases of mankind."( Ringe, JD, 2010)
"Osteoporosis is a major and global public health concern."( Barbagallo, M; Dominguez, LJ; Scalisi, R, 2010)
"Osteoporosis is a frequent problem in disorders characterized by iron overload, such as the thalassemias and hereditary hemochromatosis."( Boskey, AL; Coleman, R; Cunningham-Rundles, S; Doty, SB; Giardina, PJ; Grady, RW; Lin, H; Mayer-Kuckuk, P; Ross, FP; Tsay, J; Vogiatzi, MG; Yang, Z, 2010)
"Osteoporosis is characterized by the occurrence of a host of fractures."( Boutsen, Y; Devogelaer, JP; Manicourt, DH, 2010)
"Osteoporosis is a common complication of aging."( Barton, BA; Bouxsein, ML; Brown, KM; Hannan, MT; Kiel, DP; Lang, TF; Magaziner, J; Rubin, CT; Shane, E; Zimmerman, S, 2010)
"Osteoporosis is characterized by reduced bone mass and structural deterioration of bone tissue leading to enhanced bone fragility and a consequent increase in fracture risk."( Altavilla, D; Bitto, A; D'Anna, R; Granese, R; Irrera, N; Marini, H; Minutoli, L; Polito, F; Squadrito, F, 2010)
"Osteopenia and osteoporosis are considered major health problems in patients suffering from thalassemia due to increased life expectancy of those patients."( Atfy, M; Fathy, A; Mansor, H; Saeed, J; Salah, H, 2010)
"Undertreatment of osteoporosis is common, even for high-risk patients."( Arora, T; Becker, DJ; Colon-Emeric, C; Curtis, JR; Delzell, E; Kilgore, ML; Matthews, RS; Morrisey, MA; Saag, KG; Safford, MM; Taylor, A; Warriner, A, 2010)
"Drug-induced osteoporosis is common and has a significant impact on the prognosis of patients suffering from chronic debilitating diseases."( Canalis, E; Giustina, A; Mazziotti, G, 2010)
"Steroid-induced osteoporosis is a serious adverse effect of this drug."( Amemiya, N; Itabashi, M; Karasawa, K; Kawanishi, K; Kojima, C; Moriyama, T; Nitta, K; Ogawa, T; Shimizu, A; Shiohira, S; Sugiura, H; Takei, T; Tsuchiya, K; Tsukada, M; Uchida, K, 2010)
"Osteoporosis is a slow progressive disease with develops over decades, and where intervention is needed for an extended number of years."( Bay-Jensen, AC; Christiansen, C; Henriksen, K; Karsdal, MA, 2010)
"Osteoporosis is prevalent in men presenting with prostate cancer and also a common side effect of treatment with luteinizing hormone-releasing hormone agonists, which are associated with decreased BMD and loss of lean body mass and suppress testosterone, unlike bicalutamide, which results in an increase in serum testosterone and oestrogen levels."( Parr, NJ; Wadhwa, VK; Weston, R, 2011)
"Osteoporosis is one of the recognized features of AS."( Huang, CH; Hung, PS; Lee, HS; Shiu, LJ; Tsay, MD; Wei, JC; Wong, RH, 2011)
"Osteoporosis is characterized by reduced bone mass and deterioration of bone microarchitecture, resulting in bone fragility and increased susceptibility to fractures."( Marie, PJ, 2010)
"Osteoporosis is now considered a major health problem in all developed and in most developing (non-African) countries."( Neuprez, A; Reginster, JY, 2010)
"Osteoporosis is a major health problem worldwide, and most current therapy used in osteoporosis treatment acts by either increasing bone formation or decreasing bone resorption."( Kim, HK; Lee, S; Leem, KH, 2011)
"Osteoporosis is currently a major public health problem and with predicted demographic changes, its future health and economic impact is likely to be phenomenal."( Prabhoo, R; Prabhoo, TR, 2010)
"Osteoporosis is not a constant feature in young patients with KS, even without testosterone substitution."( Bständig, B; Fénichel, P; Ferrari, P; Hiéronimus, S; Le Duff, F; Lussiez, V, 2011)
"Osteoporosis is a common consequence of androgen deprivation therapy (ADT) for prostate cancer."( Adler, RA, 2011)
"Osteoporosis is a multifactorial disorder with a strong genetic component and vitamin D receptor gene has been suggested as a candidate gene for osteoporosis."( Ajeya Kumar, P; Aruna, P; Jyothy, A; Narasimulu, G; Pulla Reddy, B; Sesha Charyulu, M; Sri Manjari, K; Venkata Karunakar, K; Yasovanthi, J, 2011)
"Osteoporosis is a systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture."( Chen, D; Huang, J; Shi, Q; Tang, DZ; Wang, YJ; Yang, F; Yang, Z, 2011)
"After patients with osteoporosis are identified, the challenge is to treat them appropriately."( Smith, EM, 2011)
"Osteoporosis is a bone disease that leads to an increased risk of fracture."( Bian, JS; Hu, LF; Lu, M; Wang, XY; Wu, ZY; Xiao, DM; Xu, ZS, 2011)
"Risk factors for osteoporosis are prevalent in chronic heroin users who often start using opiates in their late teens."( Bloch, N; Dürsteler-MacFarland, KM; Kowalewski, R; Kraenzlin, ME; Stohler, R; Wiesbeck, GA, 2011)
"COPD and osteoporosis are strongly associated because of common risk factors such as age, smoking, and inactivity."( Boonen, S; Decramer, M; Janssens, W; Lehouck, A, 2011)
"Osteoporosis is the most common systemic skeletal disease characterized by low bone mass, increased bone turnover, and subsequent increased susceptibility to fracture."( Blat, D; Komosińska-Vassev, K; Olczyk, K; Olczyk, P, 2010)
"Osteoporosis is a common disease characterised by a systemic impairment of bone mass and microarchitecture that results in fragility fractures."( Hofbauer, LC; Khosla, S; Rachner, TD, 2011)
"Osteoporosis is a result of the disruption of bone homeostasis that is carried out by bone-forming osteoblasts and bone-degrading osteoclasts."( Leong, WF; Li, B; Ling Chau, JF; Wang, X, 2011)
"Osteoporosis is a common condition associated with aging but has been considered to primarily affect women because of the substantial effect of menopause on osteoporosis."( Das, S; Gates, BJ, 2011)
"Osteoporosis is a major public health issue in Japan, and key factors for its prevention are diet and exercise."( Muraki, S, 2011)
"Osteoporosis is a common disorder in aging populations that imposes considerable health problems."( Hashiguchi, K; Hayashida, N; Irie, S; Morishita, M; Sekitani, Y; Shinkawa, T; Taira, Y; Takamura, N; Teraoka, S; Yoshida, K, 2011)
"Osteoporosis is a multifactorial disease with a strong genetic component."( Agrawal, A; Bours, MJ; Dagnelie, PC; Gartland, A; Jorgensen, NR; Schwarz, P; Wesselius, A, 2011)
"The prevalence of osteoporosis is estimated to be 18% in men, but 30% of all fractures occur in men."( Martin, AC, 2011)
"Osteoporosis is a global public health that affects postmenopausal women due to the deficiency of estrogen, a hormone that plays an important role in the microarchitecture of bone tissue."( Da Cunha, MR; de Abreu Figueira, L; Dias Vecina, CA; Do Prado Ribeiro, DC; Issa, JP; Josédias, F, 2012)
"Osteoporosis is uncommon before menopause and dramatically increases in prevalence thereafter."( Hayashi, T, 2011)
"Osteoporosis is a major public health problem for adults above 55 years of age, which leads to an increase in bone fragility."( Brazier, M; Fardellone, P; Kamel, S; Mentaverri, R, 2012)
"Osteoporosis is caused by imbalance between osteoclastic bone resorption and osteoblastic bone formation."( Nakamura, M; Udagawa, N, 2011)
"Osteoporosis is a common complication in children with motor impairments."( Berard, C; Poirot, I; Vuillerot, C; Wagner, S, 2011)
"Osteoporosis is a common disease in later life, which has become a growing public health problem."( Müller, WE; Schloßmacher, U; Schröder, HC; Wang, X; Wiens, M, 2011)
"Osteoporosis is a highly prevalent disease and fractures at an advanced age worsen life expectancy."( Namba, N; Ozono, K, 2011)
"Post pregnancy osteoporosis is rare condition that causes fragile fracture mostly in vertebrae."( Chaki, O; Hirata, G, 2011)
"Osteoporosis is a systemic skeletal disorder which results from an imbalance in bone remodeling."( Hampson, G; Sandhu, SK, 2011)
"Osteoporosis is a proven complication of long-term glucocorticoid therapy."( Faizah, O; Farihah, HS; Nazrun, SA; Nirwana, SI; Norazlina, M; Norliza, M; Suhana, MR, 2011)
"Osteoporosis is characterized by a reduction in bone mineral density (BMD) ."( Hirose, M; Niimi, K; Yasui, T, 2011)
"Osteoporosis is a major health disorder associated with an increased risk of fracture."( Ahmadieh, H; Arabi, A, 2011)
"Osteoporosis is a multifactorial genetic disease characterized by reduction of bone mass due to dysregulation of osteoclast differentiation or maturation."( Arsenault, M; Boudiffa, M; Elfassihi, L; Ferron, M; Giroux, S; Kisseleva, M; Majerus, PW; Pata, M; Rached, M; Rousseau, F; Vacher, J, 2011)
"Because osteoporosis is often a result of aging, many people are not aware that therapies exist to reduce the risk of fracture."( Dore, RK, 2012)
"Osteoporosis is a bone disease that predisposes to fractures."( Garriguet, D, 2011)
"Osteoporosis is a condition of excessive and uncoupled bone turnover, in which osteoclastic resorption exceeds osteoblastic bone formation, resulting in an overall net bone loss, bone fragility, and morbidity."( Agrawal, A; Boeynaems, JM; Gartland, A; Robaye, B; Skerry, TM; Wang, N, 2012)
"Steroid-induced osteoporosis is a textbook example of the secondary type of this medical condition."( Sewerynek, E, 2011)
"Osteoporosis is a chronic disease of the osseous system characterised by decreased strength of bone tissue, which in turn leads to increased fracture risk."( Sewerynek, E; Stuss, M, 2011)
"Osteoporosis is a major health problem, and the economic burden is expected to rise due to an increase in life expectancy throughout the world."( Brouwer-Brolsma, EM; Brug, J; de Groot, LC; Dhonukshe-Rutten, RA; Enneman, AW; Lips, P; Swart, KM; Uitterlinden, AG; van der Velde, N; van Dijk, SC; van Meurs, JB; van Schoor, NM; van Wijngaarden, JP; Zillikens, MC, 2011)
"Osteoporosis is one of the systemic features of COPD."( Bai, P; Hou, J; Jin, J; Li, R; Sun, Y; Wang, Y; Zhang, Q, 2011)
"Osteoporosis is a common disorder in which diminished bone mass leads to progressive microarchitectural skeletal deterioration and increased fracture risk."( Drake, MT; Zhang, W, 2012)
"Osteoporosis is a common complication in long-term survivors after liver transplantation (LTX)."( Amrein, K; Dimai, HP; Dobnig, H; Fahrleitner-Pammer, A; Kniepeiss, D; Kornprat, P; Pieber, T; Tscheliessnigg, KH; Wagner, D, 2012)
"Osteoporosis is the index disease for calcium deficiency, just as rickets/osteomalacia is the index disease for vitamin D deficiency, but there is considerable overlap between them."( Nordin, BE, 2010)
"Osteoporosis is infrequently addressed during hospitalization for osteoporotic fractures."( Agulnek, A; Anderson, J; Andruszyn, L; Baker, DW; Bobb, A; Bunta, AD; Cameron, KA; Dillon, N; Edwards, BJ; Hahr, A; Kazmers, NH; May, M; O'Leary, KJ; Williams, MV, 2012)
"Osteoporosis is infrequently addressed during hospitalization for osteoporotic fractures."( Agulnek, A; Anderson, J; Andruszyn, L; Baker, DW; Bobb, A; Bunta, AD; Cameron, KA; Dillon, N; Edwards, BJ; Hahr, A; Kazmers, NH; May, M; O'Leary, KJ; Williams, MV, 2012)
"Osteoporosis is a major public health problem as a result of associated fragility fractures."( Bishop, N; Cooper, C; Fraser, R; Gandhi, SV; Harvey, NC; Javaid, K; Kennedy, S; Papageorghiou, AT; Prentice, A; Schoenmakers, I, 2012)
"Osteoporosis is a common, morbid and costly disorder characterized by deterioration in bone strength."( Maalouf, NM; Sakhaee, K; Yoon, V, 2012)
"Osteoporosis is less common in individuals with high fat mass."( Buettner, C; Iqbal, J; Sun, L; Zaidi, M, 2012)
"Primary osteoporosis is a rare childhood-onset skeletal condition whose pathogenesis has been largely unknown."( Ala-Kokko, L; Bartels, CF; Cole, WG; Deraska, D; Hartikka, H; Jüppner, H; Korvala, J; Mäkitie, O; Männikkö, M; Mora, S; Schnabel, D; Sochett, E; Warman, ML, 2012)
"Osteoporosis is a chronic disease characterized by bone loss and increased skeletal fragility."( Amling, M; Barvencik, F; Beil, FT; Clarke, IJ; Egermann, M; Oheim, R; Pogoda, P, 2012)
"Osteoporosis is a complex disease with various causes, such as estrogen loss, genetics, and aging."( Chiba, K; Fujie, A; Fujita, Y; Fukuda, K; Funayama, A; Hao, W; Hashimoto, K; Hoshi, H; Iwasaki, R; Kanagawa, H; Katsuyama, E; Kawamoto, T; Kitagawa, K; Kobayashi, T; Matsumoto, M; Miyamoto, H; Miyamoto, K; Miyamoto, T; Miyauchi, Y; Mori, T; Morioka, H; Nakayama, KI; Ohsawa, I; Ohta, S; Sano, M; Sato, Y; Toyama, Y; Yoshida, S, 2012)
"Osteoporosis is a frequent human metabolic bone disorder."( Alghamdi, HS; Bronkhorst, EM; Jansen, JA; Junker, R, 2012)
"Osteoporosis is a major public health concern in Canada and worldwide."( Buchholz, AC; Chouinard, LE; Randall Simpson, J, 2012)
"Osteoporosis is a multi-factorial disease with potential contributions from genetic, endocrine functional, exercise related and nutritional factors."( Aaseth, J; Andersen, O; Boivin, G, 2012)
"Osteoporosis is common in human immunodeficiency virus (HIV)-infected persons."( Brown, TT; Walker Harris, V, 2012)
"Osteoporosis is characterized by enhanced activity of osteoclasts relative to that of osteoblasts."( Deselm, CJ; Teitelbaum, SL; Zou, W, 2012)
"Pediatric osteoporosis is uncommon but can result in painful and debilitating insufficiency fractures."( Cheema, AM; Dominguez-Bartmess, SN; Szalay, EA; Tandberg, D, 2012)
"Osteoporosis is a worldwide health problem predominantly affecting post-menopausal women."( Boonmaleerat, K; Kongtawelert, P; Pothacharoen, P; Reutrakul, V; Wanachewin, O, 2012)
"Osteoporosis is the most common skeletal disorder and is considered a risk of fracture."( Berköz, M; Comelekoglu, U; Eroglu, P; Sagír, O; Yalin, S, 2012)
"Osteopenia and osteoporosis are diseases frequently occurring after liver transplantation (OLT)."( Hommann, M; Kaemmerer, D; Lehmann, G; Schmidt, B; Settmacher, U; Wolf, G, 2012)
"Osteoporosis is a reduction in bone mineral density (BMD)."( El-Abd, EE; El-Ashmawy, NE; El-Bahrawy, HA; Haggag, AA; Khedr, NF, 2013)
"Osteoporosis is a major growing public health problem and it is clear that much needs to be done to bridge the gap between patients and practitioners."( Abdulameer, SA; Hassali, MA; Sahib, MN; Subramaniam, K; Syed Sulaiman, SA, 2013)
"Osteoporosis is a reduction in skeletal mass due to an imbalance between bone formation and bone resorption."( Jeong, MH; Kang, SS; Kim, HK; Kim, JH; Lee, JS; Park, DS; Park, KS; Yoon, TR, 2012)
"Transient osteoporosis is a rare condition causing regional pain, immobility and functional compromise."( Jawad, AS; Shaikh, MF; Shenker, NG, 2010)
"Osteoporosis is characterized by enhanced differentiation of bone-resorbing osteoclasts, resulting in a rapid loss of functional trabecular bone."( Beyer, C; Bottesch, E; Distler, JH; Hillienhof, U; Kleyer, A; Krönke, G; Schett, G; Scholtysek, C; Tuckermann, JP, 2012)
"Osteoporosis is an important age-related bone disease characterized by increased bone turnover with insufficient bone formation relative to bone resorption."( Marie, PJ; Saidak, Z, 2012)
"Osteoporosis is defined as a continuous loss of bone mineral density accompanied by an increased fracture risk in females and males."( Kudlacek, S; Puntus, T, 2012)
"Osteoporosis is a bone disease that leads to an increased risk of fracture."( Bian, W; Huang, K; Liu, H; Liu, S, 2012)
"Treatment for osteoporosis is highly warranted in diabetic patients who have multiple risks for fractures."( Okazaki, R; Watanabe, R, 2012)
"Alcohol induced osteoporosis is characterized by a bone mass decrease and microarchitecture alterations."( Benaitreau, D; Benhamou, CL; Chappard, C; Jaffre, C; Jamme, F; Lespessailles, E; Maurel, DB; Pallu, S; Refregiers, M; Rochefort, GY, 2012)
"Osteoporosis is a major complication of chronic cholestatic liver disease (CCLD)."( de Paula, FJ; Defino, HL; Facincani, I; Jorgetti, V; Mattar, R; Pereira, FA; Ramalho, LN; Volpon, JB, 2012)
"Osteoporosis is considered a "silent" disease as there are often no discrete warning signs, until a fracture occurs; therefore, clinicians must be cognizant of the underlying risk for osteoporosis and co-morbid conditions and/or medications that accelerate risk of fracture."( Choksi, P; Taxel, P; Van Poznak, C, 2012)
"Osteoporosis is a common side effect of treatment with androgen deprivation therapy (ADT) in men with prostate cancer."( Davison, J; Millar, H, 2012)
"Osteoporosis is a chronic systemic disease characterised by bone loss and microarchitectural deterioration."( Amling, M; Ignatius, A; Oheim, R; Pogoda, P, 2012)
"Osteoporosis is a common skeletal complication seen in patients with chronic liver disease."( Carey, EJ; Yadav, A, 2013)
"Osteoporosis is characterized by poor bone quality."( Garcia, P; Histing, T; Holstein, JH; Klein, M; Kuntz, S; Menger, MD; Pohlemann, T; Scheuer, C; Stenger, D, 2013)
"Osteoporosis is a leading cause of morbidity and mortality in the elderly and influences quality of life, as well as life expectancy."( Faliva, MA; Opizzi, A; Perna, S; Rondanelli, M, 2013)
"Osteoporosis is a debilitating condition characterized by fractures, pain and premature death."( Andersen, S; Jakobsen, A; Laurberg, P; Vestergaard, P, 2013)
"Osteoporosis is recognized as the disease of females; however, males are also affected and have serious consequences thereof."( Agrawal, NK; Sharma, B, 2013)
"Postmenopausal osteoporosis is a complicated and multi-factorial disease."( A, J; Li, J; Liu, J; Liu, Y; Ma, B; Sun, J; Wang, Y; Wu, D; Ying, H; Zhang, Q, 2013)
"Osteoporosis is a widespread disease characterised by low bone mass and structural deterioration of bone resulting in an increased susceptibility to fractures."( Alt, V; Böcker, W; Elkhassawna, T; Govindarajan, P; Heiss, C; Hemdan, NY; Lips, KS; Schlewitz, G; Schliefke, N; Schnettler, R; Thormann, U; Zahner, D, 2013)
"Because osteoporosis is associated with increased bone marrow fat content, which in principal can alter DTI parameters, the goal of this study was to examine the potential of MD and FA, in combination with bone marrow fat fraction (FF), to discriminate between healthy, osteopenic and osteoporotic subjects, classified according to DXA criteria."( Assako, EP; Capuani, S; Fanucci, E; Iundusi, R; Manenti, G; Masala, S; Simonetti, G; Sorge, R; Tarantino, U, 2013)
"Osteoporosis is defined as a reduction of bone density or the presence of a fragility fracture."( Amiri, AH; Tarrahi, MJ, 2011)
"Osteoporosis is a disease characterised by low bone mass and structural deterioration of bone tissue leading to bone fragility."( Leonardi, R; Loreto, C; Musumeci, G; Pichler, K; Reuber, T; Weinberg, AM, 2013)
"Osteoporosis is a common pathological condition that influences 20 % of women over 50 years of age."( Jiang, Y; Li, N; Wooley, PH; Xu, Z; Yang, SY, 2013)
"Osteoporosis is prevalent among Malaysian patients with inflammatory bowel disease and is associated with a 6-fold increased risk of fractures."( Ananda, V; Arumugam, K; Goh, KL; Hilmi, I; Sarji, SA; Sunderesvaran, K, 2013)
"The risk of osteoporosis is reduced as TGF-β1 increases and increases as OPG was raised."( Chen, C; Chen, P; Gong, JJ; He, HB; Lei, DD; Liao, EY; Luo, XH; Wu, XP; Xie, GQ; Zhang, H, 2013)
"Both CKD and osteoporosis are frequently observed in the same patients, and often have parallel progression in postmenopausal women."( Cheng, MH; Lee, FK; Lee, WL; Tarng, DC; Wang, PH; Yang, WC, 2013)
"Osteoporosis is a skeletal disorder characterized by loss of bone mass, decreased bone strength, and an increased risk of bone fracture."( Imai, K, 2013)
"Osteoporosis is a skeletal disease leading to an increased risk of bone fracture."( Abedinpoor, A; Chen, A; Dodge, TR; Hamamura, K; Tanjung, N; Yokota, H; Zhang, P, 2013)
"Osteoporosis is one of the major complications of glucocorticoid therapy."( Fujii, N; Hamano, T; Inoue, K; Isaka, Y; Kusunoki, Y; Matsui, I; Mikami, S; Nakano, C; Nango, N; Obi, Y; Rakugi, H; Shimomura, A; Tomida, K; Tsubakihara, Y, 2014)
"Osteoporosis is a common bone metabolic disorder affecting both men and women."( Abdul-Majeed, S; Mohamed, N; Soelaiman, IN, 2013)
"Osteoporosis is posing a tremendous healthcare problem globally."( Chin, KY; Mo, H; Soelaiman, IN, 2013)
"Osteoporosis is a bone pathology leading to increase fractures risk and challenging quality of life."( Coxam, V; Guicheux, J; Léotoing, L; Miot-Noirault, E; Wauquier, F; Wittrant, Y, 2013)
"Osteoporosis is a major public health concern, characterized by low bone mass and structural deterioration of bone tissue, leading to bone fragility and an increased susceptibility to fracture."( Feola, M; Liuni, FM; Pistillo, P; Saturnino, L; Scialdoni, A; Tarantino, U; Tempesta, V, 2013)
"Osteoporosis is a high mortality and morbidity ranged skeletal disease and results in high costs of medical care in the European Union."( Albayrak, A; Bayir, Y; Bilen, H; Cadirci, E; Halici, Z; Karakus, E; Polat, B; Sahin, A; Yuksel, TN, 2013)
"Osteoporosis is one of the deleterious side effects of long-term glucocorticoid therapy."( Böcker, W; Dürselen, L; Faulenbach, M; Govindarajan, P; Heiss, C; Huerter, B; Kampschulte, M; Khassawna, T, 2013)
"Secondary osteoporosis is also common in men, and causes include androgen deprivation therapy for prostate cancer, glucocorticoid treatment and alcohol excess."( Eastell, R; Walsh, JS, 2013)
"Osteoporosis is a skeletal disorder characterized by diminished bone strength, which results in an increased risk of fracture."( Brandi, ML; Minisola, S, 2013)
"Osteoporosis is caused by an imbalance in bone remodeling, a process involving bone-building osteoblasts and bone-resorptive osteoclasts."( Brackee, G; Chen, CH; Chen, L; Chyu, MC; Jenkins, M; Kwun, IS; Mo, H; Shen, CL; Wang, S, 2013)
"Osteoporosis is a widespread disorder affecting millions of individuals of all ethnic backgrounds worldwide, particularly among older women."( Baldi, J; Celi, M; Gasbarra, E; Iundusi, R; Liuni, FM; Rao, C; Tarantino, U, 2013)
"Osteoporosis is a disease characterized by reduction in the bone mass and disruption of bone architecture leading to impaired skeletal strength and an increased susceptibility of fractures."( Behera, A; Ghosal, K; Silvanus, V; Subramanian, P, 2012)
"Because osteoporosis is a disease associated primarily with aging, we hypothesized that age-related bone loss would be attenuated in α-TTP-KO mice."( Cross, CE; Gohil, K; Iwaniec, UT; Rust, A; Smith, BJ; Stoecker, BJ; Traber, MG; Turner, RT; Vasu, VT; Zhang, B, 2013)
"Osteoporosis is a high-prevalence disease, particularly in developed countries, and results in high costs both to the individual and to society through associated fragility fractures."( Brown, L; Poudyal, H, 2013)
"Osteoporosis is a major global health problem."( Ahmad, F; Ima-Nirwana, S; Mohamad, N; Mohd Ramli, ES; Shuid, AN; Suhaimi, F, 2013)
"Osteoporosis is the consequence of an imbalance in bone remodeling caused by excessive resorption or inappropriate bone formation."( Brance, ML; Brun, LR; Di Loreto, VE; Lupo, M; Rigalli, A, 2014)
"Osteoporosis is a major global health issue in elderly people."( Cha, PH; Choi, KY; Min, do S; Zahoor, M, 2014)
"Osteoporosis is a metabolic bone disorder that affects both men and women worldwide."( Mohamed, N; Rufus, P; Shuid, AN, 2013)
"Osteoporosis is regularly mentioned as a secondary consequence of alcoholism, and chronic alcohol abuse is established as an independent risk factor for osteoporosis."( Mikosch, P, 2014)
"Osteoporosis is a common disorder characterized by compromised bone strength that predisposes patients to increased fracture risk."( Liu, J; Miao, D; Sun, W; Wang, H; Wang, Z; Wu, J; Yin, Y, 2014)
"Osteopenia and osteoporosis are common in adults with CF, especially in male patients and in patients with low lung function, body weight, and 25-OH vitamin D levels."( Gemma, S; Patel, A; Sheikh, S, 2015)
"Osteoporosis is a skeletal disorder characterized by low bone mass and increased bone fragility associated with aging, menopause, smoking, obesity, or diabetes."( Cates, JM; Cole, HA; Degen, JL; Flick, MJ; Hirotaka, H; Nyman, JS; Ohba, T; Schoenecker, JG, 2014)
"Sarcopenia and osteoporosis are important public health problems that occur concurrently."( Abreu, E; Bonewald, LF; Brotto, M; Hsu, YH; Huang, J; Karasik, D; Kiel, DP; Mo, C, 2014)
"Osteoporosis is a silent disease, characterized by a porous bone micro-structure that enhances risk for fractures and associated disabilities."( Abboud-Werner, S; Bendele, M; Callaway, D; Fajardo, R; Guda, T; Herman, B; Horn, D; Lopez-Cruzan, M; Sharma, R; Vanegas, D, 2014)
"Osteoporosis is recognized as a worldwide skeletal disorder problem."( Anburajan, M; Kumar, DA, 2014)
"Comparison of osteoporosis care in breast cancer and non-oncology populations shows that suboptimal bone health care is not isolated to prostate cancer."( Alibhai, SM; Tsang, DS, 2014)
"Osteoporosis is a progressive bone disease due to low osteoblast activity and/or high osteoclast activity."( Soo, C; Ting, K; Velasco, O; Wu, BM; Zhang, X; Zhang, Y, 2014)
"Osteoporosis is characterized by low bone mineral density and associated with low impact skeletal fractures most often involving the spine, hip, pelvis, proximal humerus and forearm."( Gosch, M; Kammerlander, C; Nicholas, JA, 2014)
"Although osteoporosis is a progressive bone disease leading to increased risk of fracture, it has rarely been investigated on a large scale in older people with intellectual disabilities (ID)."( Bastiaanse, LP; Echteld, MA; Evenhuis, HM; Mergler, S, 2014)
"Osteoporosis is complicated by the occurrence of fragility fractures."( Felder, M; Ferrari, S; Krieg, MA; Lamy, O; Meier, C; Mellinghoff, HU; Rizzoli, R, 2014)
"Osteoporosis is a chief complication in patients with anorexia nervosa."( Araki, M; Hotta, M; Ohwada, R; Urano, A, 2015)
"Osteoporosis is the prevalent manifestation of bone involvement in patients with systemic mastocytosis."( Adami, S; Biondan, M; Bonadonna, P; Gatti, D; Idolazzi, L; Orsolini, G; Rossini, M; Tripi, G; Viapiana, O; Zanotti, R, 2014)
"Osteoporosis is an asymptomatic, systemic bone disease characterized by low bone mass and microarchitectural deterioration of bone tissue, resulting in increased bone fragility."( Balercia, G; Biagioli, A; Tirabassi, G, 2014)
"Osteoporosis is a chronic disease with an increasing prevalence due to the ageing of the population."( Duquet, N, 2014)
"In Singapore, male osteoporosis is gaining greater importance due to our ageing population."( Goh, LH; How, CH; Lau, TC, 2014)
"Osteoporosis is a common, costly and serious disease, which is still too often regarded as an inevitable part of the normal ageing process and therefore sub-optimally treated, especially in the elderly--in fact, only two out of every 10 patients who sustain a hip fracture receive any form of assessment or prophylactic therapy for osteoporosis."( Brown, SL; Cassim, B; Davey, MR; de Lange, W; de Villiers, TJ; Ellis, GC; Hough, FS; Lipschitz, S; Lukhele, M; Pettifor, JM, 2014)
"Osteoporosis is a disease characterized by low bone mineral density (BMD) and increased risk of fractures."( Boue, SM; Bunnell, BA; Burow, ME; Elliott, S; Gimble, JM; Jiang, Q; Ohlstein, JF; Strong, AL; Wang, G; Zhang, Q; Zheng, S, 2014)
"The incidence of osteoporosis is high in MHD patients."( Fan, WF; Gu, Y; Niu, JY; Wu, Q; Xiao, DM; Ye, XW, 2014)
"Osteoporosis is one of the most common bone diseases in the world and results from an imbalance of bone cell functions."( Deng, F; Ji, Y; Qiu, H; Wang, L; Watts, DC; Wu, X; You, T, 2014)
"Osteoporosis is a disease with great importance in current public health due to the associated risk of fracture; therefore, a rapid and accurate diagnosis becomes increasingly important."( de Souza, RA; Mussatto, JC; Pacheco, MT; Perez, MC; Silveira, L; Zângaro, RA, 2015)
"Osteoporosis is a major public health issue that is expected to rise as the global population ages."( Tou, JC, 2015)
"Osteoporosis is one of the skeletal manifestations of NF1, which is associated with increased fracture risk."( Benlidayi, IC; Kozanoglu, E; Ortac, EA, 2015)
"Osteoporosis is a common health problem."( Malek, HA; Samir, SM, 2014)
"Osteoporosis is a progressive systemic skeletal disease, in which the equilibrium of bone resorption and bone formation is disturbed."( Cai, K; Dong, Y; Hu, X; Jin, Y; Liu, J; Ma, J; Wu, G; Zhang, H, 2014)
"Osteoporosis is a systemic and metabolic bone disease."( Dai, L; Hu, M; Shen, Z; Wang, Y; Wu, H; Xu, M; Xue, L; Yuan, D; Zhao, H, 2016)
"Osteoporosis is simulated in rats by chronic administration of omeprazole or serotonin for 6 months; investigated bone status in the model of liver fibrosis and the administration of serotonin against liver fibrosis."( Puzikov, AM, 2014)
"The target to treat osteoporosis is prevention for future fractures."( Gorai, I, 2015)
"Urolithiasis and osteoporosis are two multifactorial diseases which are evidently reciprocal."( Balaban, J; Bijelic, R; Milicevic, S, 2014)
"Osteoporosis is a condition characterized by a reduced bone mass and a compromized resistance of bone against mechanical loads, which has led us to hypothesize that mechanotransduction by osteocytes is altered in osteoporosis."( Bacabac, RG; Bakker, AD; Klein-Nulend, J; van Oers, RF, 2015)
"Osteoporosis is regarded as one of the chronic complications of diabetes mellitus that results from reduced bone formation and increased resorption."( El-Maraghy, SA; Mehana, NA, 2015)
"Osteoporosis is caused by excessive activity of bone-degrading osteoclasts over bone-forming osteoblast."( Blangy, A; Busson, M; Cherfils, J; Cres, G; Ferrandez, Y; Malaval, L; Planson, AG; Richard, C; Vives, V; Zeghouf, M, 2015)
"Osteoporosis is a disorder of bones with increasing risk among women."( Garg, V; Kochhar, A; Munshi, R, 2015)
"Osteoporosis is a disease characterized by loss of bone mass and degeneration of the microstructure of bone."( Cong, L; Guo, DW; Han, YX; Liang, D; Tu, GJ, 2015)
"The intervention of osteoporosis is considered to be one part of bone fracture treatment."( Fan, FY; Kuo, CL; Wu, CC; Yang, KC, 2015)
"Osteoporosis is more commonly found in women, thus making women more susceptible to fracture than men."( Matsushita, H; Wakatsuki, A, 2015)
"Osteoporosis is a skeletal disorder characterized by decreased mass and compromised bone strength predisposing to an increased risk of fractures."( Canalis, E; Mirza, F, 2015)
"Atherosclerosis and osteoporosis are the leading causes of mortality and morbidity."( Rajamannan, NM, 2015)
"Osteoporosis is a chronic disease associated with decreased bone density that afflicts millions of people worldwide."( Moreau, R; Roberts, JL, 2015)
"Diabetic osteoporosis is gradually attracted people's attention."( Meng, HZ; Yang, MW; Zhang, WL, 2015)
"Osteoporosis is a major cause of fractures and associated morbidity in the aged population."( Ellinger, I; Föger-Samwald, U; Mechtcheriakova, D; Meshcheryakova, A; Pietschmann, P, 2016)
"Generalized osteoporosis is common in patients with inflammatory diseases, possibly because of circulating inflammatory factors that affect osteoblast and osteoclast formation and activity."( Bakker, AD; Bravenboer, N; Klein-Nulend, J; Lems, WF; Luyten, FP; Pathak, JL; Verschueren, P, 2015)
"Osteoporosis is a disease of the bones resulting in low bone mass that induces fragile bones and hence susceptibility of fracture."( Chung, YT; Liou, SH; Pan, WH; Tsai, TL; Tseng, YC; Wang, SL; Wu, TN, 2016)
"Osteoporosis is a disease characterized by low bone mass and progressive destruction of bone microstructure, resulting in increased the risk of fracture."( Li, F; Li, Y; Lv, J; Ma, J; Ma, X; Meng, X; Sun, X; Zhang, Y; Zhao, B, 2015)
"Osteoporosis is a major disease associated with aging."( Amstislavskaya, TG; Chen, JH; Ho, YJ; Hsu, CY; Huang, CW; Hung, CS; Kao, PF; Kolosova, NG; Tikhonova, MA; Ting, CH; Tseng, GT, 2015)
"Osteoporosis is a systemic skeletal disease with the high incidence, serious complications, financial burden, and heavily decrease in living quality."( Bai, YB; Guo, LX; Liu, XD; Ma, YZ; Xi, JC; Xue, HB; Zang, HY, 2015)
"Osteoporosis is a syndrome of excessive skeletal fragility characterized by the loss of mass and deterioration of microarchitecture in bone."( Li, W; Liu, H; Liu, Y; Zhang, X; Zhou, Y, 2015)
"Osteoporosis is a common and under-diagnosed disease characterized by the systemic impairment and structural deterioration of bone tissue, leading to bone fragility and an increased risk of fractures of the hip, spine, and wrist."( Kageyama, G, 2015)
"Osteoporosis is one of the most common bone diseases, which is characterized by a systemic impairment of bone mass and fragility fractures."( Huang, CX; Lv, B; Wang, Y, 2015)
"Rates of osteoporosis are significantly lower in regions of the world where olive oil consumption is a dietary cornerstone."( Bradshaw, HB; Leishman, E, 2016)
"Osteoporosis is one of the most prevalent bone diseases worldwide and is characterised by high levels of bone turnover, a marked loss in bone mass and accumulation of microdamage, which leads to an increased fracture incidence that places a huge burden on global health care systems."( Curtin, CM; Duffy, GP; Lee, TC; McCoy, RJ; Mulcahy, LE; O'Brien, FJ; Taylor, D, 2015)
"Osteoporosis is an osteolytic disease that features enhanced osteoclast formation and bone resorption."( Cheng, J; Lin, X; Liu, Q; Tickner, J; Wang, T; Xu, J; Yang, M; Yao, J; Yuan, J; Zhao, J; Zhou, L, 2016)
"Osteoporosis is a global public health problem currently affecting more than 200 million people worldwide."( Murray, IR; Simpson, AH, 2016)
"Osteoporosis is the radiological image of osteopenia, a pathological concept meaning a smaller quantity of bone per unit of volume."( Alaminos, M; Campos, A; Cano, JR; Crespo, PV; Cruz, E; Guerado, E; Sánchez-Quevedo, Mdel C, 2016)
"Osteoporosis is the most important factor related to changes in periprosthetic bone mass."( Čellár, R; Lacko, M; Schreierová, D; Vaško, G, 2015)
"Osteoporosis is a systemic disease characterized by bone degradation and decreased bone mass that promotes increased bone fragility and eventual fracture risk."( Buzalaf, MA; Chiba, FY; de Cássia Alves Nunes, R; de Lima Coutinho Mattera, MS; Ervolino, E; Louzada, MJ; Pereira, AG; Pereira, RF; Silva, CA; Sumida, DH, 2016)
"Osteoporosis is a growing concern among people living with HIV (PLWH) because of the recognized risk of fractures, which bring with them morbidity and mortality."( Negredo, E; Warriner, AH, 2016)
"Osteoporosis is recognized as an issue for PLWH."( Negredo, E; Warriner, AH, 2016)
"Osteoporosis is one of the most frequent manifestations of systemic mastocytosis, particularly in adults."( Adami, S; Bonadonna, P; Gatti, D; Idolazzi, L; Kunnathully, V; Orsolini, G; Rossini, M; Tripi, G; Viapiana, O; Zamò, A; Zanotti, R, 2016)
"Male osteoporosis is a multifactorial disease, although it is often in part related to hypogonadism."( Weber, TJ, 2016)
"Osteoporosis is a common complication in patients with rheumatoid arthritis (RA)."( Chen, S; Gong, Y; Peng, J; Xiao, Z; Zeng, Q; Zhang, Y, 2016)
"Osteoporosis is common in Chinese patients with RA."( Chen, S; Gong, Y; Peng, J; Xiao, Z; Zeng, Q; Zhang, Y, 2016)
"Osteoporosis is a systemic skeletal disease characterized by low bone mass and micro-architectural deterioration of bone tissue with a consequent increase in bone fragility and susceptibility to fracture."( Bhardwaj, A; Osunkwo, I; Sinha, NK; Swe, KM, 2016)
"Osteoporosis is a bone pathology leading to increased fracture risk and challenging the quality of life."( Madhyastha, H; Madhyastha, R; Maruyama, M; Nakajima, Y; Pengjam, Y; Yamaguchi, Y, 2016)
"Osteoporosis is a degenerative bone disease commonly related to aging."( Barry, M; Cross, L; Gaharwar, AK; Pearce, H; Tatullo, M, 2016)
"Osteoporosis is a most frequent systemic skeletal disease characterized as low bone mineral density and microarchitectural deterioration of bone tissue, resulting in increased bone fragility and fracture risk."( Baloch, Z; Huo, Q; Ma, T; Shi, Q; Xie, Y; Zhou, H, 2017)
"Osteoporosis is one of the most prevalent skeletal system diseases."( Li, X; Yang, HL; Zhang, YY; Zhou, ZY, 2016)
"Osteoporosis is a disorder of bone in which the mass of the bone is reduced and the bone's architecture at the microscopic level is disordered."( Frassetto, LA; Sebastian, A, 2016)
"Osteoporosis is a systemic skeletal disease, which is characterized by a systemic destruction of bone mass and microarchitecture."( Bi, Y; Li, Y; Pu, W; Yan, Z; Yuan, X; Zhou, K, 2016)
"Osteoporosis is a significant health problem in the developing countries and its prevalence data are important for the estimation of health care burden and policy making."( Chin, KY; Ima-Nirwana, S; Kamaruddin, AA; Low, NY, 2016)
"Osteoporosis is defined by decreased bone density and microarchitectural deterioration that predispose to fragility fractures."( Matikainen, N, 2016)
"Osteoporosis is a common complication of chronic obstructive pulmonary disease (COPD)."( Kochetkova, E; Maistrovskaia, Y; Nevzorova, V; Ugay, L, 2016)
"Osteoporosis is a significant public health issue affecting over half of women aged over 50."( Chan, CK; Cooper, C; Dennison, E; Mason, A, 2016)
"Obesity and osteoporosis are often concurrently happened in the menopausal women."( Cui, L; Fu, Z; Huang, J; Huang, M; Lee, WYW; Li, G; Liang, Y; Lin, S; Suen, CW; Wu, H; Wu, T; Xu, L, 2016)
"Osteoporosis is more frequent in inflammatory bowel disease (IBD) patients."( Drwęska-Matelska, N; Eder, P; Kaczmarek-Ryś, M; Krela-Kaźmierczak, I; Linke, K; Marcinkowska, M; Michalak, M; Skrzypczak-Zielińska, M; Szymczak, A; Słomski, R; Wysocka, E; Łykowska-Szuber, L, 2016)
"Osteoporosis is a condition causing significant morbidity and mortality in the elderly population worldwide."( Chin, KY; Mohamad, NV; Soelaiman, IN, 2016)
"Osteoporosis is a chronic disease that impairs proper bone remodeling."( Beloti, MM; Bombonato-Prado, KF; de Almeida, AL; de Oliveira, FS; de Sousa, LG; Gimenes, R; Hallak Regalo, SC; Rosa, AL; Scalize, PH; Semprini, M; Siessere, S, 2016)
"Osteoporosis is a major health threat nowadays."( Kõks, S; Laius, O; Maasalu, K; Märtson, A, 2016)
"Osteoporosis is a complication of androgen deprivation therapy (ADT) in men with prostate carcinoma."( Balsano, M; Doria, C; Maestretti, G; Mosele, GR; Scarpa, RM; Solla, F, 2017)
"Postmenopausal osteoporosis is characterized by a reduction in the number of sinusoidal and arterial capillaries in the bone marrow and reduced bone perfusion."( Li, F; Lv, J; Ma, J; Ma, X; Song, N; Sun, L; Sun, X; Zhao, Z, 2017)
"Osteoporosis is a risk factor for implant fixation failure."( Ai, D; Bai, D; Han, X; Shu, R; Song, J; Zhao, M, 2017)
"Osteoporosis is a major skeletal disease with low bone mineral density, which leads to an increased risk of bone fracture."( Gao, Z; Gou, F; Guo, J; Li, J; Li, X; Liu, D; Tan, N; Wang, Z; Yang, S; Yokota, H; Zhang, J; Zhang, P; Zhao, X, 2017)
"Osteoporosis is a bone disease that afflicts millions of people around the world, and a variety of spinal integrity issues, such as degenerative spinal stenosis and spondylolisthesis, are frequently concomitant with osteoporosis and are sometimes treated with spinal interbody fusion surgery."( Chen, LH; Chen, WJ; Fu, TS; Ho, NY; Lai, PL; Niu, CC; Tai, CL; Tsai, TT, 2017)
"Osteoporosis is a systemic skeletal disorder characterized by low bone mineral density (BMD) that leads to an increase in bone fragility, causing an individual to be at an increased risk for fractures."( Bass, MA; Ford, MA; Garner, JC; Haskins, MA; Nahar, VK; Nelson, KM; Sharma, M, 2016)
"Osteoporosis is a serious health problem worldwide."( Fu, X; Jing, Y; Li, D; Liu, K; Shi, Q; Tao, Y; Yang, H; Zen, K; Zhang, C; Zhang, W; Zhang, Y; Zhao, H; Zhou, X, 2017)
"Osteoporosis is a metabolic skeletal disease characterized by an imbalance between osteoclast-mediated bone resorption and osteoblast-mediated bone formation."( Calignano, A; Corrado, B; Lama, A; Mattace Raso, G; Meli, R; Paciello, O; Pagano, TB; Pirozzi, C; Russo, S; Santoro, A, 2017)
"The treatment of osteoporosis is generally either by inhibition of bone resorption with antiresorptive agents or by stimulation of bone formation with anabolic agents."( Chew, CK; Clarke, BL, 2017)
"Prevalence of osteoporosis is increasing both in developed and developing countries."( Khashayar, P; Larijani, B; Salari, P; Tabatabaei-Malazy, O, 2017)
"Osteoporosis is found to have high prevalence after gastrectomy and therefore, it is important to prevent this condition by means of effective medication, such as alendronate sodium hydrate."( Akiyama, H; Endo, I; Izumisawa, Y; Kosaka, T; Kunisaki, C; Miyamoto, H; Sato, K; Sato, S; Suematsu, H; Taguri, M; Tanaka, Y; Yamanaka, T; Yukawa, N, 2017)
"Osteoporosis is characterised by trabecular bone loss resulting from increased osteoclast activation and unbalanced coupling between resorption and formation, which induces a thinning of trabeculae and trabecular perforations."( Abel, RL; Atwood, R; Bhattacharya, R; Boughton, OR; Cobb, JP; Goh, EL; Hansen, U; Jin, A; Karunaratne, A; Ma, S; Patel, B; Vo, NT, 2017)
"Osteoporosis is a common disease causing fracture in older populations."( Chen, S; Liu, J; Wang, Y; Wu, X; Xiang, T; Yang, Y; Zhou, H, 2017)
"It is known that osteoporosis is the most prevalent short-term complication in type 1 diabetes mellitus."( Gazzaruso, C; Montalcini, T; Pujia, A, 2017)
"Osteoporosis is a major public health problem associated with many factors, and it affects more than 50% of women over 50 years old."( Alp, HH; Başbugan, Y; Ediz, L; Huyut, Z; Şekeroğlu, MR; Yildirim, S, 2017)
"Osteoporosis is a disease characterized by structural deterioration of bone tissue, leading to skeletal fragility with increased fracture risk."( Chen, XY; Gao, CY; Gou, ZR; Ma, L; Mou, XZ; Ting, K; Wang, LH; Wang, XW; Xu, SZ; Yang, F; Yang, GJ; Yang, XY; Zhang, L; Zhang, XL; Zou, H, 2017)
"Osteoporosis is a serious public health concern worldwide."( He, S; Hu, J; Liu, W; Mao, Z; Ning, R; Yan, B; Yang, J; Zhan, Y, 2017)
"Osteoporosis is associated with widespread periodontitis and impaired periodontal healing."( Chen, Y; Du, Z; Jiang, J; Lin, M; Luo, K; Xiao, Y; Yan, F; Zheng, B, 2017)
"Osteoporosis is an emerging threat to patients with lipodystrophy."( Huang, L; Shi, H; Zhou, X, 2017)
"Osteoporosis is one of the most common diseases worldwide."( Gleitz, S; Hoffmann, DB; Komrakova, M; Kosinsky, RL; Menger, B; Nguyen, HH; Saul, D; Sehmisch, S; Wassmann, M, 2017)
"Osteoporosis is characterized by the imbalance of two relatively independent processes-osteoblastogenesis and osteoclastogenesis."( Bian, Z; He, Q; Li, M; Tian, F; Wang, X; Yao, W; Zhang, J; Zhu, L, 2017)
"Osteoporosis is a common bone disorder where the declined bone mass is far more than normal physiological status and usually associated with enhanced fracture risk, reduced bone strength and even deteriorated quality of life."( Hu, J; Huang, H; Huang, J; Tan, X; Xie, Y; Zou, P, 2017)
"Osteoporosis is a significant public health problem, and a major cause of the disease is estrogen deficiency following menopause in women."( Khosla, S; Monroe, DG, 2018)
"In old age, osteoporosis is associated with a substantial burden in terms of morbidity and mortality."( Flamaing, J; Gielen, E; Luyten, FP; Vandenbroucke, A, 2017)
"Osteoporosis is a common skeletal disease with serious consequences due to osteoporotic fractures and high costs to society for post-fracture care."( Lewiecki, EM; Lovato, C, 2017)
"Osteoporosis is characterized by low bone mass and qualitative structural abnormalities of bone tissue, leading to increased bone fragility that results in fractures."( Cipriani, C; Minisola, S; Occhiuto, M; Pepe, J, 2017)
"Osteoporosis is characterized by a reduction in bone mass and bone mineral density, which weakens the bone."( Wang, S; Wang, X; Yan, C; Zhang, D; Zhang, M, 2017)
"Osteoporosis is one of the most prevalent forms of age-related bone diseases."( Antika, LD; Choi, YJ; Kang, MK; Kang, YH; Kim, DY; Kim, YH; Lee, EJ; Oh, H; Park, SH, 2017)
"Idiopathic juvenile osteoporosis is a primary osteoporosis of unknown aetiology present in previously well children and is a diagnosis of exclusion."( Lim, SY; Tan, LO; Vasanwala, RF, 2017)
"BACKGROUND Osteoporosis is diagnosed by bone loss using a radiological parameter called T-score."( Böcker, W; Daghma, DES; El Khassawna, T; Engelhardt, M; Heiss, C; Ivo, M; Kauschke, V; Kern, S; Lips, KS; Malhan, D; Rezwan, K; Schmitt, J; Stoetzel, S; Tushtev, K, 2017)
"Osteoporosis is a major health problem in postmenopausal women and the elderly that leads to fractures associated with substantial morbidity and mortality."( Chen, TH; Chen, WY; Chien, JL; Chou, SJ; Chu, TH; Lu, KC; Shyu, JF; Wang, JW; Yeh, CB; Yen, MH, 2018)
"Osteoporosis is a disease characterized by low bone mass and progressive destruction of bone microstructure, resulting in increasing the risk of fracture."( Cui, YL; Li, H; Li, RX; Liu, TJ; Lu, YR; Wang, GF; Wang, QS; Zhang, CQ; Zhang, XZ, 2018)
"Regional migratory osteoporosis is a rare, but probably underdiagnosed condition with an unclear etiology."( Bours, S; Peeters, HRM; Spierings, J, 2018)
"Osteoporosis is a common disease characterised by reduced bone mass and an increased risk of fragility fractures."( Beattie, JR; Bell, SEJ; Brennan, O; Caraher, MC; Cummins, NM; Idris, AI; O'Brien, FJ; O'Driscoll, O; Ralston, SH; Sophocleous, A; Towler, M, 2018)
"Osteoporosis is a progressive bone disorder characterised by imbalance between bone building (anabolism) and resorption (catabolism)."( Cook, AE; Diepenhorst, N; Langmead, CJ; Pastoureau, P; Rueda, P; Sabatini, M, 2018)
"Osteoporosis is a bone disease characterized by reduced bone mass, which leads to increased risk of bone fractures, and poses a significant risk to public health, especially in the elderly population."( Peng, S; Wang, D; Wang, Z; Yang, D; Zhang, J; Zhen, W, 2018)
"Osteoporosis is an aging process of skeletal tissues with characteristics of reductions in bone mass and microarchitectural deterioration of bone tissue."( Hu, ZQ; Tang, YH; Xin, DW; Xiong, ZF; Xu, CD; Yue, ZS; Zeng, LR, 2018)
"Postmenopausal osteoporosis is a highly prevalent disease."( Cano, A; Chedraui, P; Goulis, DG; Lambrinoudaki, I; Lopes, P; Mishra, G; Mueck, A; Rees, M; Senturk, LM; Simoncini, T; Stevenson, JC; Stute, P; Tuomikoski, P, 2018)
"Osteoporosis is often accompanied by sarcopenia."( Ahrabi, A; Böker, KO; Harlas, B; Hoffmann, DB; Komrakova, M; Kosinsky, RL; Saul, D; Sehmisch, S; Wassmann, M; Wigger, R, 2018)
"Postmenopausal osteoporosis is a common systemic skeletal disease that is associated with estrogen‑deficiency."( Liu, X; Lu, E; Mao, C; Qin, A; Xu, X; Zhang, X, 2018)
"Osteoporosis is a global public health concern and, it can result from numerous pathogenic mechanisms, many of which are closely related with age, nutritional disorders, endocrine imbalance, or adverse drug side effects presented by glucocorticoids, heparin, and anti-epileptics."( Huang, Y; Leng, B; Li, X; Lin, J; Mei, X; Pan, Y; Qiu, J; Su, Y; Xing, C; Xu, J; Xue, Y; Zhang, W, 2018)
"Osteoporosis is a disease characterized by low bone mass, most commonly caused by an increase in bone resorption that is not matched by sufficient bone formation."( Han, JJ; Kim, D; Kim, J; Kim, MS; Koo, MA; Kwon, BJ; Lee, MH; Park, JC; Seon, GM, 2018)
"Osteoporosis is a metabolic bone disease characterized by low bone mass and micro-architectural deterioration of bone, for which the underlying mechanism is an imbalance between bone resorption and bone remodeling."( Chen, X; Hu, HG; Li, Q; Li, X; Liu, C; Su, J; Weng, W; Zhi, X; Zou, Y, 2018)
"Culprits of osteoporosis are no longer a matter of speculation based on in vitro observations."( Manolagas, SC, 2018)
"Osteoporosis is a frequent disease among the elderly especially in postmenopausal women."( Wan, JB; Wang, C; Wang, Y; Yan, C; Zhang, D; Zhang, M; Zhang, Q, 2018)
"Osteoporosis is a skeletal disorder characterized by diminished bone strength that increases the risk of fracture at instances of trivial trauma."( Arora, D; Arora, M; Chawla, J; Sharma, N; Shukla, L, 2018)
"Osteoporosis is a frequent complication in patients with chronic liver disease, especially in end-stages and in chronic cholestasis, in addition to non-alcoholic fatty liver disease, haemochromatosis and alcoholism."( Guañabens, N; Parés, A, 2018)
"Osteoporosis is linked to reduced bone mineral density (BMD) as a major risk factor for fragility fractures."( Chai, Y; Hu, C; Lu, S; Wang, Y; Zhong, W; Zhu, Y, 2018)
"Osteoporosis is characterized by a reduction of the bone mineral density (BMD) and microarchitectural deterioration of the bone, which lead to bone fragility and susceptibility to fracture."( Hong, SG; Hwang, YH; Kim, KJ; Kim, SJ; Mun, SK; Son, YJ; Yee, ST, 2018)
"Postmenopausal osteoporosis is a global health issue."( Shan, BC; Wang, L; Wang, S; Wang, X; Xu, YJ; Yang, F; Yuan, Y; Zhang, H; Zhang, P; Zhou, ZQ, 2018)
"Key Points Osteoporosis is common, difficult to detect and usually untreated."( Almqvist, EG; Boström, KB; Dalemo, S; Eggertsen, R; Hjerpe, P, 2018)
"Osteoporosis is difficult to treat and is still incurable, and thus prevention is critically important."( John Cecily, HS, 2020)
"Osteoporosis is a chronic disease in which the skeleton loses a weighty proportion of its mineralized mass and mechanical pliability."( Abdallah, HM; Abdel-Naim, AB; Al-Abbasi, FA; Al-Abd, AM; Algandaby, MM; Alghamdi, AA; Eid, BG; El-Halawany, AM, 2018)
"Osteoporosis is a debilitating skeletal side effect of androgen deprivation therapy based on gonadotropin-releasing hormone (GnRH) agonist in men."( Chin, KY; Mohamad, NV; Soelaiman, IN, 2018)
"Osteoporosis is a silent skeletal disease characterized by low bone mass and destruction of skeletal microarchitecture, leading to an increased fracture risk."( Chin, KY; Ghafar, NA; Hasan, WNW; Jolly, JJ; Soelaiman, IN, 2018)
"Diabetes-associated osteoporosis is mainly caused by the formation and accumulation of advanced glycation end products (AGEs)."( Chen, H; Cheng, YZ; Wang, JY; Wang, LT; Yang, L; Yang, SL; Ye, M; Zhang, H; Zhuo, XY, 2018)
"Postmenopausal osteoporosis is a common disorder accompanied with estrogen deficiency in women."( Elfiky, AA; Sayed, AA, 2018)
"Postmenopausal osteoporosis is closely related with the increase of reactive oxygen species and the decrease of antioxidant levels."( Bai, XC; Gu, WQ; Li, M; Liu, J; Xia, Y; Xiao, X; Zhao, YY; Zhou, XJ, 2018)
"Osteoporosis is defined as a loss of bone mass and deterioration of its architecture resulting in bone weakness, which becomes prone to fracture."( Liu, X; Xu, X, 2018)
"Post-menopausal osteoporosis is a bone formation disorder induced by estrogen deficiency."( Fu, X; Shao, B; Yang, D; Yu, Y, 2018)
"Osteoporosis is one of the most common skeletal disorders affecting a significant percentage of people worldwide."( Calciolari, E; Dereka, X; Donos, N; Mardas, N, 2018)
"Osteoporosis is a multifactorial disease with a strong genetic influence."( Abedian, Z; Akhavan-Niaki, H; Amjadi-Moheb, F; Eftekhari, H; Heidari, L; Hosseini, SR; Mafi Golchin, M; Mousavi Kani, SN; Nooreddini, H; Pourbagher, R; Pourreza Baboli, H, 2018)
"Osteoporosis is a bone disorder characterized by bone loss and decreased bone strength."( Areeckal, AS; Kamath, J; Kocher, M; S, SD; Zawadynski, S, 2018)
"Osteoporosis is a major debilitating cause of fractures and decreases the quality of life in elderly patients."( Challa, VS; Guntuku, L; Naidu, VGM; Ramavat, RN; Thummuri, D, 2018)
"Osteoporosis is one of the major health problems worldwide."( Das, N; Gupta, T; Imran, S, 2019)
"BACKGROUND Osteoporosis is a major health risk for women worldwide."( Fang, J; Gao, K; Huang, C; Li, H; Zhu, J, 2018)
"Osteoporosis is a major health issue, especially in older women."( Kalkan, R; Tulay, P, 2018)
"Osteoporosis is observed in TI and TM."( Alfaqih, MA; Alqudah, S; Barqawi, M; Bashir, N; Khader, Y; Saadeh, R, 2018)
"Osteoporosis is an important health problem in India owing to the prevalence of vitamin D deficiency across all ages, low level of awareness and higher risk of complications."( Ahmad, I; Arshad, MD; Das, SK; Jafar, T; Mahdi, AA; Mahdi, F; Rizvi, I; Waliullah, S, 2016)
"Osteoporosis is a systemic skeletal disorder characterizedby reduced bone mass, deteriorated bone structure."( Chen, C; Wang, J; Wu, Y; Xing, X; Ye, S, 2019)
"Osteoporosis is a systemic bone disease which leads to a reduction in bone mass."( Al-E-Ahmad, A; Faghihzadeh, S; Fathi, M; Hosseini, SR; Mosapour, A; Nooreddini, HG; Parsian, H, 2018)
"Osteoporosis is the most common bone disease in humans."( Aly, H; Bhattacharya, P; Chiocca, EA; Cui, Y; Fu, J; Jiang, J; Johnson, MD; Lawler, SE; Liu, Y; Luo, C; Ma, H; Reiter, RJ; Rozental, R; Wang, X; Yang, H; Yang, Q; Yao, J; Zhang, X; Zhou, S, 2019)
"Osteoporosis is the most common osteolytic disease characterized by excessive osteoclast formation and resultant bone loss, which afflicts millions of patients around the world."( Cao, Z; Chen, K; Jin, H; Kenny, J; Liu, Q; Liu, Y; Tickner, J; Wang, Q; Wang, Z; Xu, H; Xu, J; Xu, K; Yao, L, 2019)
"Osteoporosis is defined by low bone mineral density (BMD), which is mainly due to the imbalances in osteoclast and osteoblast activity."( Chang, WC; Chen, BK; Cho, EC; Hsu, YW; Hung, KS; Ikegawa, S; Liao, HT; Lu, HF; Wong, HS, 2018)
"Osteoporosis is a common bone disorder that increases susceptibility to fragility bone fractures."( Jalali, RK; Jha, S; Kaushal, N; Vohora, D, 2019)
"Osteoporosis is characterized by decrease in bone mass and microarchitectural changes in the bone that increases fracture risk."( Dasarathy, J; Labrador, H, 2018)
"Osteoporosis is a condition characterized by decreased bone density and bone strength, commonly observed among older individuals."( Chen, B; Lin, FF; Liu, Y; Lu, QP; Qiu, YR; Xiao, B; Yang, J; Yang, RB; Zhang, MH; Zheng, K, 2019)
"Osteoporosis is a bone metabolic disease that affects mostly post-menopausal women."( da Cunha, M; de Siqueira, D; Eis, SR; Gomes-Rochette, NF; Graceli, JB; Miguel, EC; Neto, HAR; Oliveira, ALA; Pedrosa, DF; Rangel, LBA; Resgala, LCR; Santana, HS; Silva, IV; Soares, ODR, 2018)
"Osteoporosis is a form of osteolytic disease caused by an imbalance in bone homeostasis, with reductions in osteoblast bone formation, and augmented osteoclast formation and resorption resulting in reduced bone mass."( Chen, L; He, W; Hong, Z; Kuek, V; Liu, Y; Shao, M; Sun, Y; Tickner, J; Wang, C; Wang, H; Xu, J; Yang, F; Zhou, C; Zou, X, 2019)
"Osteoporosis is the most common metabolic bone disease and a major public health problem worldwide."( Cheng, L; Zhang, K; Zhang, Z, 2018)
"Osteoporosis is a common complication of cerebral palsy and Rett's syndrome."( Brezin, F; Dousset, B; Feillet, F; Hernandez, M; Lambert, L; Renard, E; Weryha, G; Wiedemann, A, 2019)
"Osteoporosis is a disorder categorized based on the bone mineral density (BMD) and an alteration in the bone micro-architecture had been considered as the major determinant for increasing the fracture risk."( Hu, Z; Tang, Y; Xiong, Z; Yue, Z; Zheng, W, 2019)
"Osteoporosis is a metabolic bone lesion in which the bone mass is reduced per unit volume due to increased bone resorption."( Chen, X; Guo, S; Li, S; Liu, B; Liu, T; Ouyang, Z; Peng, D; Shen, Y; Wan, L; Yin, Z; Zhang, Q; Zhu, W, 2019)
"BACKGROUND Osteoporosis is a common disorder leading to bone loss."( Dai, X; Ding, W; Shang, X; Zhu, D; Zhu, W, 2019)
"Osteoporosis is a systemic skeletal disease of fragility fractures due to the loss of mass and deterioration of the microarchitecture of bone."( Bi, DD; Guo, YF; Han, MH; Hao, T; Liu, H; Qi, XY; Wang, XG; Wang, XT; Zhang, BX, 2019)
"Osteoporosis is a bone-incapacitating malady and it is characterized by obvious bone mass loss and bone microarchitecture deterioration."( Bian, T; Huang, J; Li, C; Liu, Z; Lyu, J; Pi, F; Sun, X; Wei, J; Zhong, Z, 2019)
"Osteoporosis is a chronic condition and long-term, sometimes lifelong, management is required."( Compston, JE; Leslie, WD; McClung, MR, 2019)
"Osteoporosis is a common comorbidity in non-cystic fibrosis (non-CF) bronchiectasis patients."( Chung, FT; Huang, HY; Lin, CW; Lo, CY; Pan, YB; Sheng, TF; Wang, CH; Wang, TW; Yang, LY, 2019)
"Osteoporosis is a chronic bone lytic disease, because of inadequate bone ossification and/or excessive bone resorption."( Chen, L; Feng, H; Li, Z; Lian, Z; Lin, X; Liu, Q; Song, F; Wang, X; Xie, D; Xu, J; Yao, G; Yuan, G; Zheng, J; Zhou, M, 2019)
"Osteoporosis is a systemic skeletal disease that causes bone weakness and fragility."( Katsuzaki, H; Kuriya, K; Nishio, M; Nishise, M; Okamoto, H; Umekawa, H; Wada, S, 2019)
"Osteoporosis is a multifactorial disease in which genetic factors and epigenetic modifications play a major role."( Ashma, R; Raje, MM, 2019)
"Osteoporosis is a common disorder of bone remodeling, marked by excessive osteoclast formation."( Han, SY; Kim, YK, 2019)
"Osteoporosis is a disease that is characterized by deterioration of bone tissue and increased risk of fracture as it leads to a decrease in bone mineral density, which is an important public health problem."( Inal Kabala, S; Ozcan, HM; Yagar, H, 2019)
"Male osteoporosis is a significant but undetermined healthcare problem."( Chin, KY; Ima-Nirwana, S, 2019)
"Osteoporosis is common in total joint arthroplasty (TJA) patients and likely contributes to the increasing incidence of periprosthetic fracture."( Anderson, PA; Bernatz, JT; Binkley, NC; Brooks, AE; Illgen, RI; Squire, MW, 2019)
"Osteoporosis is a worldwide epidemic but pharmacological agents to stimulate new bone formation are scarce."( Burkhart, C; Haberhauer, G; Heusch, G; Keul, P; Levkau, B; Manthe, K; Vaidya, M; von Wnuck Lipinski, K; Weske, S, 2019)
"Osteoporosis is a systemic disease with progressive bone loss."( Yang, DH; Yang, MY, 2019)
"Diabetic osteoporosis is a severe public health concern in the world."( Guo, CJ; Hong, RH; Liang, YM; Pan, HS; Xie, JJ; Zhang, FG, 2019)
"Osteoporosis is a common health problem in India, which leads to significant morbidity and mortality in elderly individuals."( Asha, HS; Cherian, KE; Kapoor, N; Kuriakose, C; Paul, TV; Thakur, P, 2020)
"Osteoporosis is the most common disease involving bone degeneration."( Lozano, D; Manzano, M; Mora-Raimundo, P; Vallet-Regí, M, 2019)
"Osteoporosis is a prevalent condition among postmenopausal women, and lacks satisfactory therapeutic options."( Chen, G; Pan, L; Sun, J; Wang, S; Wu, G, 2019)
"Osteoporosis is manifested by reduced bone mass."( Cheng, L; Wang, F; Wang, L; Wang, N; Zhang, B, 2019)
"Osteoporosis is an ageing disease characterized by elevated osteoclastic bone resorption resulting in bone loss, decrease bone strength, and elevated incidence of fractures."( Chen, L; Chen, S; Chen, Y; Cheng, X; Chu, B; Guo, D; Hong, D; Hong, Z; Li, Z; Wang, J, 2019)
"Osteoporosis is a growing health problem in Asian countries with a rapidly expanding aging population."( Aziz, NA; Chan, CY; Chin, KY; Fairus, A; Ima-Nirwana, S; Mohamed, N; Mohd Rizal, AM; Muhammad, N; Ng, PY; Nor Aini, J; Subramaniam, S, 2019)
"Osteoporosis is one of the most frequent diseases related with age."( Chen, C; Hu, J; Liang, J; Liu, H; Liu, X; Zhao, H, 2019)
"Osteoporosis is a common skeletal disorder resulting in elevated fracture risk."( Chen, L; Gan, N; Shao, B; Yang, D; Yu, Y; Zheng, X, 2019)
"Osteoporosis is a clinical condition characterized by low bone strength that leads to an increased risk of fracture."( Choi, Y; Kim, JK; Kim, P; Kim, WJ; Lee, G; Lee, JS; Nam, YJ; Seo, JH; Song, MJ; Yang, J; Yi, SS, 2019)
"Osteoporosis is an abnormal bone remodeling condition characterized by decreased bone density, which leads to high risks of fracture."( Choi, CW; Huh, D; Jeong, SY; Jin, HS; Jo, M; Kim, J; Kim, MC; Lee, JW; Lee, SW; Li, WY; Park, E; Park, JH; Park, S; Yeo, S, 2019)
"Osteoporosis is a common metabolic bone disease that is often seen in bedridden patients and astronauts."( Gao, X; Qu, H; Wang, Z; Yi, J; Zhao, H, 2019)
"Osteoporosis is a skeletal disease with decreased bone mass and alteration in microarchitecture of bone tissue, and these changes put patients in risk of bone fracture."( Lu, HX; Wang, J, 2019)
"Osteoporosis is closely associated with the dysfunction of bone metabolism, which is caused by the imbalance between new bone formation and bone resorption."( Bamba, D; Bi, Z; Cai, B; Ding, F; Feng, C; Fu, Y; Gao, M; Gong, R; He, M; Huang, Q; Jin, M; Li, Y; Liu, T; Ma, W; Reiters, R; Sukhareva, N; Sun, Y; Xu, C; Yan, G; Yang, F; Yang, L; Yuan, Y; Zhang, L, 2019)
"BACKGROUND Osteoporosis is a common osteopathy, resulting in fractures, especially in elder people."( Ma, ZP; Yang, Y; Yang, YF; Zhang, ZF, 2019)
"Osteoporosis is characterized by a progressive increase in bone fragility, leading to low bone mass and structural deterioration of bone tissue."( Chu, C; Hao, W; Mao, Z; Su, H; Zhu, Y, 2019)
"Osteoporosis is characterized by low bone mass and density, as well as change in microarchitecture of bone tissue leading to decreased bone strength."( Amelia, Y; Ernanda, SA; Jonatan, A; Juwono, MA; Kartikaningtyas, AN; Maulidya, E; Parhusip, YM; Sananta, P, 2019)
"Osteoporosis is a continuous process of loss of bone tissue."( Chang, WH; Chen, RM; Lee, YW; Liu, SH; Wang, JL; Wang, W; Yeh, PS, 2019)
"Postmenopausal osteoporosis is a common condition characterized by the increase and activation of osteoclasts."( Guo, TM; Liu, GX; Qiao, XM; Xing, YL; Yang, L; Zhu, HY, 2019)
"Osteoporosis is a chronic, progressive disease in which early diagnosis is very important."( Cao, Y; Gao, K; Li, H; Li, Q; Liu, W; Ma, D; Yu, W; Zhu, W, 2019)
"Osteoporosis is one of the most commonly diagnosed age-related bone diseases worldwide, and it is also one of the leading causes of fracture."( Ding, S; Ding, W; Hu, P; Li, J; Pan, L; Peng, Z; Zhang, T, 2019)
"Osteoporosis is a chronic disease whose symptoms include a reduction in bone strength, osteopenia, and damage to the bone microstructure."( Hou, T; Yang, X; Zhang, L, 2019)
"Osteoporosis is a common bone disease resulting from imbalance between bone formation and bone resorption."( Ahn, CB; Hyung, JH; Je, JY; Oh, Y, 2019)
"Osteoporosis is highly prevalent in older persons."( Al Saedi, A; Duque, G; Nurgali, K; Sharma, S; Summers, MA, 2020)
"Postmenopausal osteoporosis is a common and disabling disorder that increases the risk of bone fractures due to estrogen deprivation; this can be simulated in rats by ovariectomy."( Abdel-Naim, AB; Barakat, BM; Elshaer, SS; Fayed, HA; Menze, ET, 2019)
"Osteoporosis is a skeleton disease affecting 55% of people over age 60, and the number is still increasing due to an ageing population."( Hu, H; Li, ZH; Liao, MM; Liu, GD; Ran, B; Wu, YC; Zhang, PG; Zhang, XY, 2020)
"Osteoporosis is a skeletal disorder commonly found among the elderly, in which the bones become weak, brittle, and more susceptible to fracture."( Abd Aziz, N; Chan, CY; Chin, KY; Fairus, A; Ima-Nirwana, S; Jamil, NA; Mohamed, N; Muhammad, N; Ng, PY; Subramaniam, S, 2019)
"Osteoporosis is a bone disease characterized by microarchitectural deterioration, low bone mass, and increased risk of fractures."( Jin, Y; Li, L; Ma, C; Tang, Y; Xu, Y; Yang, J, 2019)
"Osteoporosis is the most widespread metabolic bone disease characterized by decreased bone mass and bone quality, and its diagnosis and treatment remains challenging."( Cai, J; He, B; Wei, J; Wu, T; Zheng, H, 2020)
"Osteoporosis is widely regarded as one of the typical aging-related diseases due to the impairment of bone remodeling."( Guo, L; Jiang, T; Wang, Y; Yang, X, 2019)
"Osteoporosis is an age-related deterioration in bone health that is, at least in part, a stem cell disease."( Aguilar-Perez, A; Barrett, T; Bragg, RT; Eisa, N; Elmansi, A; Fulzele, S; Hamrick, M; Hill, W; Isales, C; Kondrikov, D; Kondrikova, G; Lawrence, MM; Mobley, T; Schoeinlein, P; Shi, XM, 2020)
"Osteoporosis is caused by disturbance in the dynamic balance of bone remodelling, a physiological process, vital for maintenance of healthy bone tissue in adult humans."( Bai, B; Chen, L; Shen, Z; Tang, J; Wang, B; Weng, S; Wu, ZY; Xie, Z; Yan, DY; Yang, L, 2020)
"Osteoporosis is also associated with abnormalities of the kynurenine pathway, reflected in an inversion of the ratio between blood levels of the metabolites anthranilic acid and 3-hydroxy-anthranilic acid."( Clanchy, FI; Huang, YS; Ogbechi, J; Stone, TW; Topping, LM; Williams, RO, 2020)
"Osteoporosis is a chronic bone metabolism disorder affecting millions of the world population."( Li, TT; Tzeng, CM; Wang, HL; Yang, F; Zhao, Y, 2020)
"Osteoporosis is a metabolic disease characterized by reduced osteoblast differentiation and proliferation."( Hu, M; Li, Y; Liu, X; Lu, W; Wang, D; Zhang, X; Zhang, Y, 2020)
"Osteoporosis is a devastating disease that features reduced bone quantity and microstructure, which causes fragility fracture and increases mortality, especially in the aged population."( Feng, H; Fu, F; Hu, X; Li, Z; Lin, X; Liu, Q; Shao, S; Song, F; Xu, J; Yuan, G; Zhao, J; Zhou, M, 2020)
"BACKGROUND Osteoporosis is a metabolic osteopathy characterized by abnormal bone mass and microstructure that has become a public health problem worldwide."( Dai, W; Sun, Y; Zhong, G, 2020)
"Osteoporosis is the most common condition contributing to 95% of fractures in older patients hospitalized for fracture treatment."( Bail, HJ; Gosch, M; Grueninger, S; Kammerlander, C; Stumpf, U; Wicklein, S, 2020)
"Osteoporosis is a severe health problem causing bone fragility and consequent fracture."( Chen, L; Fang, K; Hong, C; Shen, L; Shen, Z; Tang, J; Wang, B; Weng, S; Wu, Z; Xie, J; Xie, Z; Yan, D; Yang, L, 2020)
"Osteoporosis is a progressive systemic disease characterized by low bone mineral density and deterioration of bone microarchitecture."( Zhang, J, 2020)
"Osteoporosis is a very common disease all over the world, in which a reduction in bone density can lead to an increased risk of fractures and a diminished physical height."( Bender, T; Conrad, R; Emmert, D; Heuchemer, L; Kasapovic, A; Marinova, M; Mücke, M; Rasche, T, 2020)
"Osteoporosis is a common chronic disease in the elderly population and in some domestic animals."( Hu, Y; Huang, J; Tong, X; Yu, Z; Zhang, L; Zhou, Z, 2020)
"Osteoporosis is the most widespread metabolic bone disease which represents a major public health burden."( Boccaccini, AR; Camargo, WA; Detsch, R; Diba, M; Grünewald, A; Kabiri, Y; Kentgens, APM; Leeuwenburgh, SCG; van den Beucken, JJJP; Zinkevich, T, 2019)
"Pharmacotherapy of osteoporosis is the main treatment option for these patients because of strong evidence about the efficacy of available drugs targeting bone metabolism."( Gimigliano, F; Iolascon, G; Liguori, S; Moretti, A; Paoletta, M; Toro, G, 2020)
"Osteoporosis is commonly underdiagnosed and undertreated."( Chuah, SL; Lau, BK; Lee, HK; Leong, TS; Tan, FHS; Teh, CL; Wan, SA, 2020)
"Osteoporosis is primarily asymptomatic, and patients with OP suffer from pain, inconvenience, economic pressure and osteoporotic fracture (OPF)."( Chen, R; Lee, WH; Shen, ZQ; Sun, Y; Zhao, HB; Zhu, D, 2020)
"Osteoporosis is a metabolic bone disease characterized by low bone density resulting in increased fracture susceptibility."( Aglan, HA; Ahmed, HH; Ali, MAM; Amr, KS; Mahmoud, NS; Mohamed, MR, 2020)
"Osteoporosis is a metabolic disease that affects bone tissue and is highly associated with bone fractures."( Barrioni, BR; Martins, T; Mosqueira, L; Ocarino, NM; Pereira, MM; Serakides, R, 2020)
"Osteoporosis is a common metabolic bone disorder in the elderly population."( Chi, X; Han, Y; Li, F; Li, Z; Qin, Y; Wang, Y; Xiao, J; Xie, W, 2020)
"Osteoporosis is a chronic condition that reflects reduced bone strength and an associated increased risk for fracture."( Bauer, DC; Clarke, BL; Drake, MT; Tsourdi, E; Yu, EW, 2020)
"Postmenopausal osteoporosis is very common in women."( Chen, Y; Hu, X; Xia, C; Xie, Z; Yang, M; Zhang, Y, 2020)
"Osteoporosis is common in postmenopausal women and elderly people."( Chien, RC; Huang, CW; Lin, IJ; Liu, YM; Mau, CZ; Mau, JL, 2020)
"Most patients with osteoporosis are postmenopausal women or elderly people with hypoimmunity, so the osteoporosis clinic has become a new hotspot for corona virus infection."( Niu, JJ; Shi, JW; Song, DW; Yang, HL; Zou, J, 2020)
"Osteoporosis is one of the major health issues associated with menopause-related estrogen deficiency."( Chin, KY; Ima-Nirwana, S; Mohamad, NV, 2020)
"Osteoporosis is a metabolic bone disease that is characterized by decreased bone density and strength due to excessive loss of bone protein and mineral content, which can be induced by increased osteoclast activity."( Huang, MZ; Ning, X; Shang, XW; Shen, ZM; Zhang, H; Zhuang, Y, 2020)
"Osteoporosis is a chronic disease of low bone mass and fragility."( Goetz, V; Homik, J; Kendler, D; Koller, G; McAlister, FA; Vandermeer, B; Ye, C, 2020)
"Osteoporosis is a common and debilitating condition characterized by diminished bone mass and architecture leading to bone fragility."( Anderson, PA; Freedman, BA; Thompson, JC; Wanderman, N, 2020)
"Osteoporosis is a major problem in patients with Duchenne muscular dystrophy (DMD), due to glucocorticoid therapy and muscle weakness."( Hornung, L; Khoury, JC; Rutter, MM; Rybalsky, I; Shellenbarger, KC; Tian, C; Wong, BL, 2020)
"Osteoporosis is a common complication in patients with primary biliary cholangitis."( Combalia, A; Guañabens, N; Jurado, S; Monegal, A; Parés, A; Peris, P; Ruiz-Gaspà, S, 2020)
"Osteoporosis is a bone disease affecting more than 2 million people comprising 1 in 3 women and 1 in 5 men in Canada."( Arora, H; Bhullar, KS; Shang, N; Wu, J, 2020)
"Osteoporosis is a systemic disease that typically affects older adults and that remains a major threat to global public health owing to its high morbidity and mortality rates."( Bao, Y; Lv, X; Ma, B; Tang, Y; Wang, G; Wang, J; Wen, X; Zhang, J, 2020)
"Osteoporosis is a common bone disorder with adverse effects on oral osseointegration, and the effects of metformin on bone metabolism have received increasing attention."( Du, S; Jiang, H; Lin, J; Shen, X; Xu, R, 2020)
"Osteoporosis is a degenerative disease characterized by reduced bone mass, in which deregulated bone remodeling by osteoclasts and osteoblasts is a main pathogenesis."( Bae, EJ; Choi, S; Moon, YJ; Park, BH; Ryoo, GH; Ryu, JH, 2020)
"Osteoporosis is the most common metabolic bone disease."( Huang, N; Li, H; Shao, B; Wu, Y; Yuan, Q; Zhao, Q, 2020)
"Osteoporosis is a global chronic disease characterized by severe bone loss and high susceptibility to fragile fracture."( Chen, K; Chen, P; Fan, S; Gu, C; Li, M; Lin, X; Liu, X; Liu, Z; Pan, H; Tang, R; Tang, Z; Wang, Q, 2020)
"Osteoporosis is the most prevalent metabolic bone disease and one of the most important postmenopausal consequences."( Koohpeyma, F; Mostafavi-Pour, Z; Savardashtaki, A; Vakili, S; Zal, F, 2021)
"Osteoporosis is characterised by impairment of microarchitecture and bone mass."( Dong, LQ; Wu, LG; Xu, C; Zeng, HB; Zhao, XH, 2020)
"Osteoporosis is an age-related disease caused by imbalanced bone remodeling resulting from excessive bone resorption."( Hong, HS; Hwang, DY; Park, JS; Piao, J; Son, Y, 2020)
"Osteoporosis is a threat to aged people who have excessive osteoclast activation and bone resorption, subsequently causing fracture and even disability."( Chen, Y; Deng, W; Ding, Z; Jie, L; Ke, M; Li, X; Qu, Y; Tan, Y; Yang, Q; Yu, Q; Zheng, J; Zou, B, 2021)
"Osteoporosis is a bone disease that mainly affects older people and postmenopausal women."( Oryan, A; Sahvieh, S, 2021)
"Osteoporosis is a major systemic disease that can significantly deteriorate the quality of life of the affected individuals."( Katz, J; Rotstein, I, 2021)
"Osteoporosis is a common metabolic bone disease with high prevalence."( Gao, YM; Ni, L; Shi, F, 2022)
"Age-related osteoporosis is characterized by the deterioration in bone volume and strength, partly due to the dysfunction of bone marrow mesenchymal stromal/stem cells (MSCs) during aging."( Chen, Y; Deng, P; Guo, Y; Li, Q; Lin, W; Liu, W; Liu, Y; Ou, G; Qi, X; Wang, C; Wang, Y; Wu, Y; Yuan, Q; Zhang, S; Zheng, X; Zhou, L, 2020)
"Osteoporosis is a disease characterized by low bone mass and an increased risk of fractures."( Burger, C; Gravius, S; Haddouti, EM; Hilgers, C; Masson, W; Pflugmacher, R; Randau, TM; Schildberg, FA, 2020)
"Osteoporosis is a major cause of morbidity and mortality worldwide and its prevention in order to avert fractures was considered of great importance in maintaining well-being and independence among the elderly."( Ringe, JD, 2020)
"Osteoporosis is a disease in which bone mineral density decreases due to abnormal activity of osteoclasts, and is commonly found in post-menopausal women who have decreased levels of female hormones."( Bae, YS; Cho, KM; Choi, CY; Kim, H; Kim, HH; Kim, KK; Kim, MK; Lee, HY; Lee, M; Park, JS, 2021)
"Background-Osteoporosis is characterized by defects in both quality and quantity of bone tissue, which imply high susceptibility to fractures with limitations of autonomy."( Beretti, F; Bertucci, E; Gatti, M; Maraldi, T; Palumbo, C; Ribeiro Luz, S; Zavatti, M, 2020)
"Osteoporosis is a common disease caused by an imbalance of processes between bone resorption by osteoclasts and bone formation by osteoblasts in postmenopausal women."( Choi, CW; Hwang, S; Jeong, H; Jeong, SY; Jin, HS; Kim, J; Lee, CG; Lim, E; Park, E; Yong, Y; Yun, SH, 2020)
"Osteoporosis is characterized by impaired bone metabolism."( Chen, L; Fang, KH; Hong, CX; Shi, X; Tang, JH; Wang, BZ; Weng, SJ; Wu, ZY; Xie, J; Xie, ZJ; Yan, DY; Yang, L, 2021)
"Osteoporosis is a prevalent systemic skeletal disorder entailing bone fragility and increased fracture risk, often emerging in post-menopausal life."( Sun, J; Wu, JC; Xu, JC; Zhang, YF; Zhou, ZY, 2021)
"Osteoporosis is an osteolytic bone condition characterized by decreased bone strength and increased bone fragility."( Chen, R; Hou, L; Li, X; Liang, J; Lin, X; Liu, Q; Su, Y; Wu, Z; Xu, F; Yang, X; Zhao, J, 2021)
"Risk factors of osteoporosis are divided into unmodifiable, namely, age, gender, genetic factors, as well as modifiable, including diet, level of physical activity, and the use of stimulants."( Dobrowolska, A; Krela-Kaźmierczak, I; Ratajczak, AE; Rychter, AM; Szymczak-Tomczak, A; Zawada, A, 2021)
"Osteoporosis is a disease with a high burden of morbidity."( Aggarwal, A; Bhadada, SK; Bhansali, A; Garg, A; Pal, R; Ram, S; Rao, SD; Sachdeva, N; Singh, P; Singh, T; Thakur, JS, 2021)
"Osteoporosis is a major public health problem around the globe including India, resulting in significant morbidity, mortality, and health care burden."( Aggarwal, A; Bhadada, SK; Bhansali, A; Garg, A; Pal, R; Ram, S; Rao, SD; Sachdeva, N; Singh, P; Singh, T; Thakur, JS, 2021)
"Osteoporosis is the most common disease involving bone degeneration."( Bi, Y; Chai, L; Huang, J; Li, Y; Liu, Y; Song, L; Wang, Q; Zhou, K, 2021)
"Osteoporosis is one of the most common extraintestinal complications among patients suffering from inflammatory bowel diseases."( Dobrowolska, A; Krela-Kaźmierczak, I; Ratajczak, AE; Rychter, AM; Zawada, A, 2021)
"Senile osteoporosis is a major public health concern, and yet, effective treatment methods do not exist."( Chen, X; Chen, Z; Wu, Y; Zhang, M; Zhou, Y, 2021)
"Osteoporosis is a metabolic skeletal disease characterized by bone loss and an increased risk of fractures."( Cha, KH; Choi, JH; Hong, S; Kim, SM; Kwon, DY; Nho, CW; Son, YJ; Yoo, G, 2021)
"Osteoporosis is a common phenomenon in HIV patients on tenofovir treatment, but its underlying mechanisms remain to be explored."( Duan, L; Li, XF; Lin, W; Liu, JZ; Ren, DC; Song, M; Zhan, ZR, 2021)
"As osteoporosis is a frequent complication in patients under chemotherapy, we investigated the effect of vitamin K2 (100 mcg menaquinone-7) and vitamin D3 (10 mcg calcitriol) on bone metabolism in children with ALL."( Abdurrezzak, U; Karakukcu, M; Muhtaroglu, S; Ozdemir, MA; Solmaz, I; Unal, E, 2021)
"Osteoporosis is a common bone disease that results in elevated risk of fracture, and delayed bone healing and impaired bone regeneration are implicated by this disease."( Abdollahifar, MA; Asgary, M; Ebrahimi, V; Fridoni, MJ; Hejazi, F; Kermani, AA; Piryaei, A; Zare, F, 2021)
"Osteoporosis is a systemic metabolic disease defined by a decreased bone mineral density, microarchitectural deterioration, and an increased incidence of fragility fractures that may lead to morbidity and mortality."( Bilgiç, E; Çetinkaya, MA; Çiftci Dede, E; Korkusuz, F; Korkusuz, P, 2022)
"Osteoporosis is a skeletal condition that is characterized by decreasing bone density and deteriorating bone mass."( Cui, X; Gao, F; Guo, S; Li, Z; Ma, M; Wang, M; Wang, X; Wang, Z, 2021)
"Osteoporosis is a skeletal disorder that is common in postmenopausal women."( Baraka, NM; El-Swefy, SE; Elseweidy, MM; Hammad, SK; Shaheen, MA, 2021)
"Osteoporosis is characterized by reductions in bone mass, which could be attributed to the dysregulation of bone homeostasis, such as the loss of balance between bone-resorbing osteoclasts and bone-forming osteoblasts."( Cheung, SYL; Lee, CW; Lee, OK; Lin, HC; Shin, RL; Wang, AY; Wang, BY, 2021)
"Osteoporosis is a major public health problem that is appeared with increasing age."( Maryamabadi, A; Nabipour, I; Nekooei, M; Shafiee, SM; Zahiri, M, 2021)
"The incidence of osteoporosis is positively correlated with age."( Bi, J; Chen, QC; Pu, YL; Zhang, Y, 2021)
"Osteoporosis is a metabolic bone-loss disease characterized by abnormally excessive osteoclast formation and bone resorption."( Fu, Z; Li, X; Qian, Y; Sun, P; Wang, K; Wang, Y; Yang, Q; Zhang, T, 2021)
"Osteoporosis is a systemic bone disease that predisposes patients to bone fracture due to decreased bone density and quality, disrupted bone microarchitecture, and increased bone fragility."( Li, YS; Ma, S; Tao, L; Tian, J; Xiao, WF; Xie, WQ; Zhang, YM, 2021)
"Osteoporosis is the most prevalent metabolic bone disorder worldwide."( Almohaileb, FI; Rasheed, Z, 2022)
"Osteoporosis is a common metabolic bone disease mainly involving bone remodeling and blood vessels."( Li, Y; Lu, J; Shen, H; Xia, L; Yang, J; Yao, L; Yuan, L; Zhang, H, 2021)
"Osteoporosis is damaging the health of women worldwide."( Liu, Y; Wang, L; Xiong, J; Yang, Y, 2021)
"Osteoporosis is a metabolic disease of the skeletal system which currently affects over 200 million patients worldwide."( Kosiorowska, J; Szymańska-Chabowska, A; Tański, W, 2021)
"Osteoporosis is a common disease in aging populations."( Chang, YW; Gu, W; Li, ZQ; Sun, J; Wei, XE; Zhu, WJ, 2021)
"Osteoporosis is a serious health problem, especially in geriatric patients."( Chen, X; Jiang, R; Liu, Z; Peng, K; Song, X; Tang, X; Zhang, Q, 2021)
"Osteoporosis is characterized by excessive bone resorption due to enhanced osteoclast activation."( Chen, Z; Han, X; He, W; He, X; Hong, G; Hong, Z; Li, Z; Pang, F; Shen, Y; Wei, Q; Wu, R; Zhou, L, 2021)
"Osteoporosis is a systemic metabolic bone disorder that is caused by an imbalance in the functions of osteoclasts and osteoblasts and is characterized by excessive bone resorption by osteoclasts."( Cheon, YH; Cho, HJ; Eun, SY; Kim, JY; Lee, CH; Lee, MS; Park, GD, 2021)
"Osteoporosis is a systemic bone disease characterized by reduced bone mass and the deterioration of bone microarchitecture leading to bone fragility and an increased risk of fractures."( Jawień, P; Nowak, B; Słupski, W, 2021)
"Osteoporosis is a chronic disease that has become a serious public health problem due to the associated reduction in quality of life and its increasing financial burden."( Kang, H; Kim, KJ; Lee, J; Lee, Y; Oh, E; Park, C; Park, KH; Son, YJ; Wang, W; Woo, GE, 2021)
"Osteoporosis is detrimental to the health of skeletal structure and significantly increases the risks of bone fracture."( Chen, Y; Gong, T; Li, Y; Meng, L; Wang, Y; Zhang, J; Zhang, Y, 2021)
"Osteoporosis is frequently accompanied by iron disorders."( Anderson, GJ; Chang, H; Chang, YZ; Duan, X; Lei, Y; Li, Y; Shen, Y; Zhang, D; Zhao, C, 2021)
"Osteoporosis is a systemic skeletal disorder characterized by reduced bone mineral density (BMD) and bone quality and increased bone porosity, which increase the risk of bone fracture."( An, N; Feng, M; Feng, W; Liu, J; Lv, C; Mao, Y; Wang, S; Wang, X; Zhong, L, 2022)
"Osteoporosis is a common disease closely associated with aging."( Gao, F; Wang, J; Wang, XH; Xia, SL; Zhou, XX, 2021)
"Osteoporosis is affecting the health of postmenopausal women in the world."( Jie, J; Li, W; Wang, G; Xu, X, 2021)
"Osteoporosis is a chronic disease characterized by low bone mass caused by increased bone turnover and impaired bone microarchitecture."( Kolmas, J; Kołodziejska, B; Stępień, N, 2021)
"Osteoporosis is skeletal fragility caused by the excessive bone resorption due to osteoclastogenesis."( Khademul Islam, ABMM; Zinnia, MA, 2021)
"Osteoporosis is common in children with cerebral palsy, particularly in children with reduced gross motor function, and leads to an increased risk of fractures."( Hurley, T; McDonald, D; McDonnell, C; Molloy, E; Stewart, P; Zareen, Z, 2021)
"Osteoporosis is a public health concern and a cause of bone loss, increased risk of skeletal fracture, and a heavy economic burden."( Guo, D; He, H; Hou, T; Li, B; Xu, W; Zhao, M, 2023)
"Osteoporosis is one of the most common diseases affecting bone metabolism."( Jiang, J; Liu, L; Luo, J; Wang, X; Weng, Z; Xu, Y; Yang, Y; Ye, J; Zhang, W; Zhou, Z, 2021)
"Osteoporosis is a worldwide healthcare challenge."( Cai, M; Chen, Y; Li, Y; Min, W; Wang, C; Wang, J; Yan, L; Zhang, R; Zhu, H, 2021)
"Osteoporosis is a debilitating disease characterized by reduced bone mineral density and an increased risk of fractures."( Brent, MB, 2021)
"Osteoporosis is a common medical condition in older ages."( Fisher Negev, T; Hadad, V; Katzir, A; Liebergall, M; Or, O; Shabtai, R; Weil, Y, 2021)
"Breast cancer and osteoporosis are common diseases that affect the survival and quality of life in postmenopausal women."( Cai, SQ; Chen, QQ; Huang, SF; Li, YZ; Lin, S; Lin, ST; Sun, XQ, 2021)
"Hypogonadism and osteoporosis are frequently reported in HIV-infected men and, besides multifactorial pathogenesis, they might be directly linked because of testicular involvement in bone health."( Cappelli, C; Castelli, F; Delbarba, A; Ferlin, A; Focà, E; Maffezzoni, F; Pezzaioli, LC; Porcelli, T; Quiros-Roldan, ME, 2022)
"Osteoporosis is a systemic bone metabolism disorder, which increases the risk of fractures, and in severe cases it may cause disability or even death."( Chen, L; Chen, Y; Gao, Y; Li, Y; Lu, Q; Mao, J; Wang, W; Zuo, J, 2022)
"Postmenopausal osteoporosis is a chronic population health hazard systemic metabolic disease caused by excessive bone resorption and reduced bone formation."( He, R; Lin, N; Qu, H; Wang, C; Zhang, Y, 2021)
"Osteoporosis is the most common skeletal disorder worldwide."( Collin, A; de Barboza, GD; Picotto, G; Rivoira, M; Rodríguez, V; Tolosa de Talamoni, N, 2022)
"Osteoporosis is one of the most common skeletal disorders caused by the imbalance between bone formation and resorption, resulting in quantitative loss of bone tissue."( Cho, YW; Choi, JS; Han, J; Jo, DG; Jung, JM; Jung, YJ; Kim, E; Kim, HK; Lee, J; Lee, KS; Park, JH; Park, SY; Sul, JH; Woo, CH; Yeom, SH; Yun, YE, 2021)
"Osteoporosis is a common and frequent disease among the elderly with a poor prognosis and high risk of fractured ankles."( Jiang, J; Li, Z; Song, X; Wan, L; Wu, D; Yuan, D; Zhang, S, 2021)
"Osteoporosis is an age-related disease characterized by low mineral density, compromised bone strength and increased risk of fragility fracture."( Dai, M; Lai, Q; Li, X; Liu, X; Liu, Y; Mo, F; Xu, H; Xu, Q; Zhan, P; Zhang, B, 2021)
"Osteoporosis is an increasing public health problem in the worldwide and has caused socioeconomic burden."( Luan, F; Shen, Z; Shi, Z; Yan, J; Zou, S, 2021)
"Osteoporosis is defined as a bone condition characterized by bone mass reduction, bone micro-architectural and quality deterioration, leading to compromised strength and increased chances of fracture."( Chen, L; Jiang, X; Lu, T; Miao, Y; Qian, Z; Shen, Y; Wang, Q; Xu, Y, 2021)
"Osteoporosis is caused by an imbalance of osteoclasts and osteoblasts, occurring in close proximity to hematopoietic cells in the bone marrow."( Agrawal, M; Bick, A; Bouxsein, ML; Brooks, DJ; Charles, JF; Cohen, DN; Ebert, BL; Evans, DM; Gibson, CJ; Griffin, G; Jaiswal, S; Kemp, JP; Kiel, DP; Kim, PG; Lin, AE; McConkey, M; Natarajan, P; Niroula, A; Pirruccello, J; Richards, JB; Sekar, A; Shin, WJ; Shkolnik, V; Słabicki, M; Tsai, JM; Uddin, MM; Wein, MN; Wong, WJ, 2021)
"Osteoporosis is characterized by increased bone fragility, and the drugs used at present to treat osteoporosis can cause adverse reactions."( Dong, J; Jiang, H; Li, W; Shen, YK; Wang, L; Wu, Q; Xian, CJ; Yao, L; Zhong, J, 2021)
"Osteoporosis is characterized by the deterioration of bone structures and decreased bone mass, leading to an increased risk of fracture."( Bak, SG; Cheong, SH; Lee, S; Lee, SJ; Lee, SW; Lim, HJ; Park, EJ; Rho, MC; Won, YS, 2021)
"Osteoporosis is a public health problem resulting in higher susceptibility to bone fracture."( Cao, S; Ding, H; Feng, T; Li, X; Li, Y; Xie, L; Yang, Q, 2022)
"Male osteoporosis is a still largely underdiagnosed pathological condition."( Bertoldo, F; Bonadonna, S; Brigo, M; Cesareo, R; Chiodini, I; De Geronimo, V; Falchetti, A; Gennari, L; Giovanelli, L; Palermo, A; Salcuni, AS; Scillitani, A; Vescini, F, 2021)
"Osteoporosis is a skeletal disorder characterized by a low bone mass and density."( Chen, S; Jing, C; Li, B; Liang, H; Liu, C; Na, H; Tan, H; Zhang, C; Zhao, L, 2021)
"Osteoporosis is a major health concern in aging populations, where 54% of the U."( Akhavan, NS; Arjmandi, BH; Foley, EM; George, KS; Hickner, RC; Kim, JS; Munoz, J; Ormsbee, LT; Siebert, SC, 2022)
"Osteoporosis is a common disease characterized by skeletal fragility and microarchitectural deterioration."( Luo, Y; Wei, JX; Xiao, JH; Xu, Y, 2022)
"Osteoporosis is a common disease in which the risk of fracture increases due to decreased bone mass and qualitative skeletal changes."( Bian, J; Chen, R; Li, M; Li, Z; Tang, J; Tian, Y; Xie, Y; Xu, X; Zhang, Y; Zhang, Z, 2022)
"Osteoporosis is an age-dependent serious skeletal disease that leads to great suffering for the patient and high social costs, especially as the global population reaches higher age."( El Shahawy, M; Gustafsson, KL; Henning, P; Koskela, A; Lerner, UH; Movérare-Skrtic, S; Nilsson, KH; Ohlsson, C; Tuckermann, J; Tuukkanen, J; Wu, J, 2022)
"Postmenopausal osteoporosis is a serious concern in aging individuals, but has not been explored for its potential to alter the shape of the inner ear by way of increased remodeling in the otic capsule."( Lees, SJ; Niccoli, S; Sanzo, P; Schroeder, L; Silcox, M; Tinius, A; Viola, B; Voth, R; Ward, DL, 2022)
"Osteoporosis is the most common bone disease and is characterized by low bone mineral density (BMD) and a high risk of fracture."( Bae, JH; Park, D, 2022)
"Osteoporosis is a serious health issue among aging postmenopausal women."( Chen, KH; Chen, LR; Cheng, CH, 2022)
"Osteoporosis is a metabolic bone disease that significantly affects the quality of life and can even lead to death."( Gu, J; Qi, J; Qiu, M; Tu, L; Xie, Y; Yang, M; Zhao, M, 2022)
"Osteoporosis is the most common diabetes complication."( Shu, L; Tang, X; Xiong, Z; Yi, P; Zhang, C, 2022)
"Osteoporosis is a bone‑related disease that results from impaired bone formation and excessive bone resorption."( Liang, D; Qiu, Y; Tang, C; Tang, G; Zhu, J, 2022)
"Osteoporosis is an independent risk factor of colorectal adenoma and high-risk adenoma."( Im, JP; Jang, DK; Jeong, JB; Kang, HW; Kim, JS; Kim, JW; Kim, SH; Koh, M; Koh, SJ; Lee, DS; Lee, KL; Lim, YJ; Nam, JH; Oh, DJ; Ryu, KH, 2022)
"Osteoporosis is a prevalent disease with a high incidence in women at the onset of menopause mainly because of hormonal changes, genetics, and lifestyle, leading to decreased bone mass and risk of fractures."( Bombonato-Prado, KF; Coelho, MC; Coppi, AA; de Sousa, LG; Fernandes, RR; Pitol, DL; Scalize, PH; Semeghini, MS; Siessere, S; Tavares, MS, 2022)
"Osteoporosis is a systemic disorder of bone metabolism."( Liu, Z; Wu, Y, 2022)
"Osteoporosis is a systemic bone disease characterized by decreased bone mass and quality and bone micro‑architecture degradation."( Cao, L; Tian, F; Wang, C; Wang, J; Zhang, Y, 2022)
"Osteoporosis is the most common metabolic bone disease in the USA and the world."( Greenspan, SL; Insogna, KL; LeBoff, MS; Lewiecki, EM; Saag, KG; Singer, AJ; Siris, ES, 2022)
"Osteoporosis is an abnormal reduction in bone mass and bone deterioration leading to increased fracture risk."( Hsieh, SC; Liu, W; Peterson, J; Tugwell, P; Wells, GA; Zheng, C, 2022)
"Osteoporosis is associated with a decrease of bone mineralized component as well as a increase of bone marrow fat."( Duan, S; Li, C; Liu, M; Qin, J; Qiu, X; Xin, Y; Yao, Q; Yuan, K; Zheng, X, 2022)
"Osteoporosis is a highly prevalent systemic skeletal disease that is characterized by low bone mass and microarchitectural bone deterioration."( Baum, T; Beer, M; Boehm, C; Carballido-Gamio, J; Dieckmeyer, M; Karampinos, DC; Karupppasamy, S; Kirschke, JS; Kloth, C; Kronthaler, S; Krug, R; Link, TM; Lisson, CG; Sollmann, N; Vogele, D, 2022)
"Osteoporosis is a general bone-related ailment characterized by reduced bone density and quality, elevated bone fragility, and fractures."( Hao, P; Li, H; Miao, B; Zhang, Y, 2022)
"Diabetes-associated osteoporosis are partly caused by accumulation of advanced glycation endproducts (AGEs)."( Chen, H; Cheng, Y; Liang, J; Liu, P; Xiang, Q; Yang, L; Zhang, H, 2022)
"Osteoporosis is a very common skeletal disorder that increases the risk of fractures."( Gan, L; Li, A; Li, L; Zhu, L; Zuo, L, 2022)
"Osteoporosis is a bone metabolic disease characterized by reduced bone mass and deterioration of bone tissue microarchitecture, leading to enhanced skeletal fragility and susceptibility to fracture."( Chen, Z; Gao, Z; Liu, X; Xiong, Z, 2022)
"Disused osteoporosis is a kind of osteoporosis, a common age-related disease."( Jia, Y; Li, B; Liu, J; Liu, X; Liu, Y; Wang, Y; Wang, Z; Xu, Y, 2022)
"Secondary osteoporosis is an important issue of clinical care in children with acute and chronic diseases."( Breda, L; Chiarelli, F; d'Angelo, DM; Di Donato, G; Di Marcello, F, 2022)
"Osteoporosis is associated with an impaired balance between bone resorption and formation, which in turn leads to bone loss and fractures."( Baloun, J; Hruskova, H; Pavelka, K; Pekacova, A; Senolt, L; Stepan, JJ; Svec, X; Wenchich, L, 2022)
"Osteoporosis is common in patients undergoing spine surgery, and carries a considerable risk of adverse outcomes."( Gomez-Salazar, MA; James, AW; Li, Z; Negri, S; Xing, X; Xu, J; Xu, M, 2022)
"Osteoporosis is a degenerative skeletal disease essentially caused by bone remodeling disorder."( Kou, Y; Li, M; Liu, H; Rong, X; Tang, R; Yang, P; Zhang, Y, 2022)
"Diabetic osteoporosis is secondary osteoporosis and a serious complication of diabetes with a high incidence rate and poor prognosis."( Ming, J; Tian, Y, 2022)
"Osteoporosis is a systemic disease in which bone mass decreases, leading to an increased risk of bone fragility and fracture."( Deng, J; Guan, Z; Lin, J; Liu, P; Tao, KT; Wang, D; Zeng, H; Zhang, W, 2023)
"Osteoporosis is a widespread bone disease that affects million cases annually."( Ayiding, X; Han, R; Li, L, 2022)
"OBJECTIVE: Osteoporosis is a severe degenerative chronic metabolic bone disease associated with high fracture risk."( Feng, G; Tu, YH; Yang, C; Yang, J; Yuan, Y, 2022)
"Osteoporosis is characterized by lowing bone mineral density."( Chen, X; Jiang, J; Zhang, Z; Zhou, H, 2022)
"Diabetes osteoporosis is considered as a metabolic bone disease of diabetes patients."( Huang, X; Li, S; Lu, W; Xiong, L, 2022)
"Osteoporosis is another frequent complication of HH, and the underlying mechanisms are poorly understood."( Altamura, S; Baschant, U; Hofbauer, LC; Muckenthaler, MU; Rauner, M; Spasić, MV; Steele-Perkins, P; Steinbicker, AU, 2022)
"Osteoporosis is considered a widespread health problem that affects senior citizens, particularly older women, after the menopause."( Ajlouni, K; Allouh, MZ; Batieha, A; El-Khateeb, M; Elsalem, L; Jaddou, H; Jumaa, D; Khader, Y; Saadeh, R, 2022)
"Osteoporosis is defined by loss of bone mass and deteriorated bone microarchitecture."( Amorim, T; Bastos, AR; Canadas, RF; Carrillo, AE; Correlo, VM; Fernandes, EM; Freitas, L; Gkiata, P; Koutedakis, Y; Kydonaki, EK; Marques, F; Ntina, G; Oliveira, JM; Pinto, R; Reguengo, H; Reis, RL; Simón, CR; Vliora, M, 2022)
"Postmenopausal osteoporosis is a critical issue for female health worldwide."( Aboutaleb, H; Ali, SS; Almged, MA; Alsanory, AA; Alsanory, TA; Ezzat, GM; Salama, RHM; Salama, THM, 2023)
"Osteoporosis is prevalent and entails alterations of vertebral bone and marrow."( Baum, T; Boehm, C; Burian, E; Dieckmeyer, M; Greve, T; Karampinos, DC; Kirschke, JS; Kloth, C; Rayudu, NM; Ruschke, S; Sollmann, N; Subburaj, K, 2022)
"Diabetic osteoporosis is a poorly managed serious skeletal complication, characterized by high fracture risk, increased bone resorption, reduced bone formation, and disrupted bone architecture."( Nirwan, N; Vohora, D, 2022)
"Among these, osteoporosis is the most common metabolic bone disorder."( Buda, R; Del Pizzo, F; Di Pietrantonio, N; Di Pietro, N; Di Tomo, P; Epifano, F; Fiorito, S; Genovese, S; Mandatori, D; Pandolfi, A; Pelusi, L; Pipino, C, 2022)
"Osteoporosis is a metabolic bone disorder associated with impaired bone microarchitecture leading to fragility fractures."( Awasthi, P; Bajpai, R; Goel, A; Khanka, S; Prakash, R; Sahasrabuddhe, AA; Sharma, K; Singh, D, 2022)
"Osteoporosis is often accompanied by bone loss with fat accumulation of the red marrow."( Kajihara, H; Kawae, N; Kimura, T; Mizushima, A; Nakamura, T; Watanabe, D; Yanagida, K; Yoshida, T, 2022)
"Osteoporosis is characterized by low bone mass and changes in bone microarchitecture that increases the risk of fracture."( Aurora, R; Veis, D, 2022)
"Osteoporosis is more common in people over 60 years old, and the possibility of modic change in 71-80y is higher than in other age groups."( Guo, H; Liu, B; Ma, X; Zhang, R; Zhang, Y, 2022)
"Osteoporosis is a metabolic, hereditary, progressive disease characterized by unusual bone production across the skeleton and a loss the bone tissue microstructure and mass."( Chen, Q; Ding, Y; Huo, J; Wei, X; Zhao, B, 2022)
"Osteoporosis is considered a risk factor for osseointegration during implant treatment."( Aita, H; Endo, K; Iijima, M; Kawamura, N; Kemuriyama, S; Koshino, H; Maida, T; Nezu, T, 2023)
"Osteoporosis is a skeletal system disease characterized by low bone mass and altered bone microarchitecture, with an increased risk of fractures."( Cui, Y; Gao, R; Li, M; Liu, H; Rong, X; Zhang, W; Zhu, S, 2022)
"Postmenopausal osteoporosis is one of the world's biggest yet unnoticed health issues."( Dhaniya, G; Gautam, S; Mishra, PR; Rai, D; Sardar, A; Sinha, S; Tripathi, AK; Trivedi, R, 2022)
"Age-induced osteoporosis is a global problem."( Lv, Z; Shi, W; Zhang, Q, 2022)
"Forearm osteoporosis is a well-known complication of primary hyperparathyroidism (PHPT)."( Aydin, H; Bozkur, E; Cakir, İ; Dogansen, SC; Esen, A; Mert, M; Metin, D; Pamuk, N; Piskinpasa, H; Sahbaz, NA; Turgut, S, 2023)
"Osteoporosis is an independent risk factor for failure after arthroscopic rotator cuff repair."( Bisazza, K; Easley, J; Gadomski, B; Johnson, JW; McGilvray, K; Nelson, B; Regan, D; Troyer, K; von Stade, D; Zhou, T, 2022)
"Osteoporosis is a common bone metabolic disease in postmenopausal women, diabetic patients and obese patients and is characterized by an imbalance in bone formation and resorption."( Li, J; Tao, L; Yang, K, 2022)
"Osteoporosis is often untreated especially in older people."( Bee, JKS; Chong, BYK; Joseph, LV; Mamun, K; Sen, HT; Wen, AFYH, 2022)
"Osteoporosis is frequently found in chronic diabetic patients, and it results in an increased risk of bone fractures occurring."( Isarankura-Na-Ayudhya, C; Klabklai, P; Phetfong, J; Supokawej, A; Tangporncharoen, R; Tawonsawatruk, T, 2022)
"Osteoporosis is becoming a global epidemic in aging societies."( Chang, YF; Hsu, YH; Hwang, JS; Li, CC; Liang, FW; Wu, CH, 2023)
"Osteoporosis is associated with alterations in the levels of specific circulating metabolites."( Huang, D; Wang, J; Wang, Y; Zeng, Y, 2022)
"Osteoporosis is a common condition in which deteriorating bone tissue results in an increased risk of low trauma fracture."( Aninye, IO; Horan, L; McPhee, C, 2022)
"Osteoporosis is a common and frequent disease among the elderly with a poor prognosis and a high risk of spinal fractures."( Li, Z; Xue, H; Zheng, R; Zhu, H, 2022)
"Osteoporosis is a common and frequent disease among the elderly with a poor prognosis and a high risk of spinal fractures."( Li, Z; Xue, H; Zheng, R; Zhu, H, 2022)
"Osteoporosis is a common and frequent disease among the elderly with a poor prognosis and a high risk of spinal fractures."( Li, Z; Xue, H; Zheng, R; Zhu, H, 2022)
"Osteoporosis is common in older adults leading to fragility fractures at enormous individual and economic cost."( Bishop, S; Gittoes, N; Langley, T; Narayanasamy, M; Paskins, Z; Sahota, O, 2022)
"Osteoporosis is common in older adults leading to fragility fractures at enormous individual and economic cost."( Bishop, S; Gittoes, N; Langley, T; Narayanasamy, M; Paskins, Z; Sahota, O, 2022)
"Osteoporosis is common in older adults leading to fragility fractures at enormous individual and economic cost."( Bishop, S; Gittoes, N; Langley, T; Narayanasamy, M; Paskins, Z; Sahota, O, 2022)
"Osteoporosis is a systemic skeletal disorder where osteoclasts are prevalent among osteoblasts."( Jeong, GS; Kang, H; Kim, EN; Kim, KH; Trang, NM, 2022)
"Osteoporosis is a systemic skeletal disorder where osteoclasts are prevalent among osteoblasts."( Jeong, GS; Kang, H; Kim, EN; Kim, KH; Trang, NM, 2022)
"Osteoporosis is a systemic skeletal disorder where osteoclasts are prevalent among osteoblasts."( Jeong, GS; Kang, H; Kim, EN; Kim, KH; Trang, NM, 2022)
"Postmenopausal osteoporosis is a significant threat to human health globally."( Chen, JX; Hu, XL; Qiu, ZC; Tang, ZL; Wong, MS; Xiao, HH; Yang, L; Zhang, FX; Zhang, J; Zhang, YY, 2022)
"Postmenopausal osteoporosis is a significant threat to human health globally."( Chen, JX; Hu, XL; Qiu, ZC; Tang, ZL; Wong, MS; Xiao, HH; Yang, L; Zhang, FX; Zhang, J; Zhang, YY, 2022)
"Postmenopausal osteoporosis is a significant threat to human health globally."( Chen, JX; Hu, XL; Qiu, ZC; Tang, ZL; Wong, MS; Xiao, HH; Yang, L; Zhang, FX; Zhang, J; Zhang, YY, 2022)
"Osteoporosis is characterized by deterioration of bone microarchitecture and reduced bone mass and can increase the risk of fracture."( Abd Elmageed, ZY; Abdelraheim, MH; Badary, DM; Farrag, MMY; Galal, HA; Mohamed, NM; Sedeek, MI, 2022)
"Osteoporosis is characterized by deterioration of bone microarchitecture and reduced bone mass and can increase the risk of fracture."( Abd Elmageed, ZY; Abdelraheim, MH; Badary, DM; Farrag, MMY; Galal, HA; Mohamed, NM; Sedeek, MI, 2022)
"Osteoporosis is characterized by deterioration of bone microarchitecture and reduced bone mass and can increase the risk of fracture."( Abd Elmageed, ZY; Abdelraheim, MH; Badary, DM; Farrag, MMY; Galal, HA; Mohamed, NM; Sedeek, MI, 2022)
"Osteoporosis is a metabolic bone disorder that leads to a decline in bone microarchitecture, predisposing individuals to catastrophic fractures."( Collins, MT; Farhadi, F; Osamor, CC; Paravastu, SS; Saboury, B; Sheppard, AJ; Wojnowski, NM, 2023)
"Osteoporosis is a metabolic bone disorder that leads to a decline in bone microarchitecture, predisposing individuals to catastrophic fractures."( Collins, MT; Farhadi, F; Osamor, CC; Paravastu, SS; Saboury, B; Sheppard, AJ; Wojnowski, NM, 2023)
"Senile osteoporosis is one of the most common age-related diseases worldwide."( He, YT; Hu, Y; Huang, YM; Kuai, Z; Lu, Y; Ren, WY; Shen, JP; Wu, JY; Wu, KF; Xu, B, 2023)
"Senile osteoporosis is one of the most common age-related diseases worldwide."( He, YT; Hu, Y; Huang, YM; Kuai, Z; Lu, Y; Ren, WY; Shen, JP; Wu, JY; Wu, KF; Xu, B, 2023)
"Background: Osteoporosis is a cardinal manifestation of Cushing’s syndrome."( Chen, JF; Chen, YN; Shen, FC; Tsai, JR, 2022)
"Background: Osteoporosis is a cardinal manifestation of Cushing’s syndrome."( Chen, JF; Chen, YN; Shen, FC; Tsai, JR, 2022)
"Osteoporosis is defined as a systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture."( Klara, J; Lewandowska-Łańcucka, J, 2022)
"Osteoporosis is defined as a systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture."( Klara, J; Lewandowska-Łańcucka, J, 2022)
"The prevalence of osteoporosis is increasing in the United States."( Ayers, C; Fu, R; Harrod, C; Kansagara, D; Kwon, A; Lazur, B, 2023)
"Osteoporosis is a complex multifactorial disease that can lead to an increased risk of fracture."( Chen, Q; Li, YH; Li, ZH; Mei, QB; Niu, YB; Song, XZ; Sun, Y; Xie, M; Zhang, YH, 2023)
"Osteoporosis is a common metabolic bone disease with a rapidly increasing prevalence, characterized by massive bone loss because of excessive osteoclast formation."( Chen, G; Dai, J; Fei, J; Hu, J; Hu, Q; Wang, Y; Ye, J; Zhang, P, 2022)
"Osteoporosis is a common and serious health issue among postmenopausal women."( Carvalho, M; Kunioka, CT; Manso, MC, 2022)
"Osteoporosis is a disorder of bone mineralisation occurring in about one third of adults with cystic fibrosis."( Chang, AB; Conwell, LS; Jeffery, TC, 2023)
"Osteoporosis is the most common bone disorder where the hyperactive osteoclasts represent the leading role during the pathogenesis."( Chen, K; Chen, L; He, J; Hu, S; Huang, F; Jiang, H; Jiang, M; Li, X; Lin, D; Lin, X; Liu, Q; Xu, J; Ye, T; Zeng, Y; Zheng, L, 2023)
"Osteoporosis is a systemic skeletal disease characterised by low bone mineral density (BMD), degeneration of bone micro-architecture, and impaired bone strength."( Azam, Z; Baghel, K; Gupta, RK; Mishra, PK; Saini, C; Sapra, L; Sinha, N; Soni, V; Srivastava, RK, 2023)
"Osteoporosis is a progressive metabolic disease characterized by decreased bone mineral density and increased fracture risk."( Han, AR; Hong, SM; Lee, AS; Lee, SH; Son, SJ; Sung, MJ, 2023)
"Osteoporosis is a common disease of the elderly that affects millions of patients worldwide."( Cao, W; Chen, Y; Dong, J; Hao, M; Hu, X; Jin, C; Ke, C; Liu, B; Peng, Z; Weng, H; Zhang, Z; Zhong, J, 2023)
"Osteoporosis is a systemic and endocrine bone disorder distinguished by declined bone mineral density, compromised bone strength, and destruction of trabecular structure."( Guo, J; Guo, Z; He, J; Ren, R; Shao, J; Sun, K; Wang, X, 2023)
"Osteoporosis is the commonest progressive metabolic bone disease, characterized by elevated risk of fragility fractures as a result of a reduced bone mass and microarchitectural deterioration."( Formosa, MM; Mangion, D; Pace, NP, 2023)
"Osteoporosis is a major health problem in postmenopausal women, and characterized by deteriorated bone mass and micro-architecture."( Du, Z; Li, Z; Lin, L; Luo, H; Luo, Z; Tang, J; Wang, S; Yuan, Z; Zhou, JR, 2023)
"Osteoporosis is a degenerative bone disease resulting from bone homeostasis imbalance regulated by osteoblasts and osteoclasts."( Dai, H; Goto, T; Kang, H; Li, F; Tu, R; Wu, X; Zhao, Y; Zhuang, P, 2023)
"Osteoporosis is a bone disease leading to bone fracture and affects 200 million women worldwide."( Azadbakht, O; Behrouj, H; Jafarinia, M; Mousavi, S; Razmjoue, D; Sabaghan, M; Sabetian, S; Savardashtaki, A; Vakili, S; Veisi, A; Zal, F, 2023)
"Postmenopausal osteoporosis is a multifactorial disease."( Gámez Nava, JI; Nuño Arana, I; Pérez Romero, M; Ruiz González, F; Trujillo Rangel, WÁ; Villagómez Vega, A, 2023)
"Osteoporosis is a progressive metabolic bone disorder characterised by a decline in bone mineral density (BMD)."( Chan, HL; Chung, PT; Ho, KH; Hsu, HY; Huang, SY; Hwang, LC; Lien, HN; Lin, HH; Ma, HC; Tsou, MT, 2023)
"Osteoporosis is a chronic disease and public health issue in aging populations."( Baldassano, D; Baldassano, S; Caldarella, R; Di Rosa, L; Sabatino, L; Vasto, S, 2023)
"Osteoporosis is a prevalent bone metabolic disease in menopause, and long-term medication is accompanied by serious side effects."( Dai, ZH; Fang, WL; He, GL; Jin, C; Jin, SQ; Ma, HW; Wu, YH; Xu, C; Xu, CY, 2023)
"Osteoporosis is an increasingly prevalent disease."( Li, X; Wang, W; Xu, H; Zhao, B, 2023)
"The problem of osteoporosis is relevant due to the high frequency of its prevalence throughout the world."( Hoina-Kardasevich, O; Shcherbeniuk, N; Yakovleva, O, 2023)
"Secondary osteoporosis is commonly caused by long-term intake of glucocorticoids (GCs), such as dexamethasone (DEX)."( Abdelaleem, EA; Arafa, EA; Elgendy, NO; Elhemely, MA; Mohamed, WR, 2023)
"Osteoporosis is a common skeletal disease; however, effective pharmacological treatments still need to be discovered."( Chen, Z; Cho, E; Ding, M; Lee, TH; Park, SW, 2023)
"Osteoporosis is a common bone disease caused by an imbalance of bone resorption and formation that results in a loss of total bone density."( Bretches, M; Dong, H; Huang, N; Jin, Z; Kang, J; Liu, R; Ning, B; Sun, Z; Yang, SY; Yu, G; Zhang, X; Zhang, Y; Zou, K, 2023)
"Osteoporosis is a highly prevalent bone disease occurred commonly in astronauts and postmenopausal women due to mechanical unloading and estrogen deficiency, respectively."( Chen, Z; Hu, L; Jia, Y; Liang, S; Liu, H; Liu, S; Qian, A; Ru, K; Wu, Z; Xu, X; Zhang, W, 2023)
"Osteoporosis is a skeletal disease characterized by low bone mass, reduced bone strength, and increased fracture risk."( Cui, Y; Di, D; Ni, Z; Wang, Q; Wei, M; Zhang, R; Zhou, H, 2023)
"Osteoporosis is a common inflammaging-related condition, where long-term accumulation of pro-inflammatory cytokines causes massive bone loss."( Dong, H; Jiang, W; Jin, Z; Kang, J; Liu, R; Ning, B; Pan, L; Sun, Z; Zhang, X; Zhang, Y, 2023)
"Osteoporosis is characterized by structural changes in the bone such as decreased bone mineral density leading to an increased risk for fractures."( Alavi, A; Høilund-Carlsen, PF; Khurana, N; Park, PSU; Raynor, WY; Resto, DA; Werner, TJ, 2023)
"Osteoporosis is a prevalent bone metabolic disease in menopause, and long-term medication is accompanied by serious side effects."( Dai, ZH; He, GL; Jin, C; Jin, SQ; Sheng, SR; Tian, NF; Wu, YH; Xie, CL; Zhao, BY; Zheng, G; Zhou, X, 2023)
"Osteoporosis is a major health problem that is very common worldwide and is characterized by both low bone density and deterioration in bone quality."( Altuntas, F; Cuneyit, I; Donmez, AC; Donmez, BO; Karagur, ER; Ocak, M; Ozturk, S; Sarikanat, M; Unal, M, 2023)
"Postmenopausal osteoporosis is a systemic metabolic disease that chronically endangers public health and is typically characterized by low bone mineral density and marked bone fragility."( Chen, J; Lian, H; Liang, J; Liu, Q; Su, Y; Wang, K; Xu, J; Yang, F; Zhao, J, 2023)
"Postmenopausal osteoporosis is a kind of degenerative disease, also described as "invisible killer."( Cai, H; He, W; Zhang, H, 2023)
"Osteoporosis is a degenerative disease characterized by reduced bone mass, with low peak bone mass being the predominant manifestation during development and having an intrauterine origin."( Chen, L; He, H; Jiang, T; Li, B; Wang, H; Xiao, H, 2023)
"Osteoporosis is a metabolic bone disease."( Cai, G; Chen, H; Chen, L; Cheng, P; Jiang, D; Lu, F; Shen, J; Sun, J; Xu, X; Zhang, J, 2023)
"The prevalence of osteoporosis is high among adult thalassemia patients."( Chansai, S; Chansung, K; Fucharoen, S; Lanamtieng, T; Phiphitaporn, P; Pongchaiyakul, C; Teawtrakul, N; Wanitpongpun, C; Yamsri, S, 2023)
"Osteoporosis is characterized by low bone mass and micro-architectural deterioration of bone tissue leading to increased bone fragility."( Bhardwaj, A; Sinha, NK; Swe, KMM, 2023)
"Osteoporosis is a metabolic bone disease that commonly results in middle-aged and elderly people following fractures."( Chen, C; Chen, R; Geng, B; Wang, H; Xia, Y; Xiao, H; Yang, C; Yang, F, 2023)
"Osteoporosis is a chronic bone disorder characterized by decreased bone mass, leading to brittle bones and fractures."( Negi, D; Rasool, N; Singh, Y, 2023)
"Postmenopausal osteoporosis is the most common type of osteoporosis."( Han, B; Han, J; Jiang, Z; Peng, Y; Sun, X; Zhang, W, 2023)
"Osteoporosis is an age-related disease of bone metabolism marked by reduced bone mineral density and impaired bone strength."( Gao, Z; Li, D; Li, Q; Liu, H; Liu, X, 2023)
"Osteoporosis is one of the chronic complications of type 1 diabetes with high risk of fracture."( Chen, X; Guo, H; Liu, J; Lv, H; Shang, P; Wang, S; Wang, Y; Wei, Y; Yang, J; Yao, W; Zhang, G; Zhen, C, 2023)
"Osteoporosis is a multifactorial disorder in which nutrition is associated with its onset and progression."( Fujita, T; Ohishi, T; Takase, H; Takeuchi, Y, 2023)
"Osteoporosis is a common metabolic bone disease that benefits from many newly developed anti-osteoporosis medications (AOMs)."( Chan, DC; Chen, HM; Fu, SH; Huang, CF; Hwang, JS; Lin, JW; Wang, CY; Wu, CH; Yang, JJ; Yang, RS; Yang, TH, 2023)
"Age-related osteoporosis is associated with increased oxidative stress and cellular senescence."( Goltzman, D; Li, J; Li, Y; Liu, B; Miao, D; Qin, R; Qiu, Y; Wang, R; Xue, Q; Yang, R; Zhang, J, 2023)
"Osteoporosis is characterized by loss of bone mass and susceptibility to fracture."( Corbetta, S; Degradi, C; Dito, G; Guabello, G; Longhi, M; Lugaresi, M, 2023)
"Osteoporosis is a bone disease characterized by structural deterioration and low bone mass, leading to fractures and significant health complications."( Akkouch, A; Frase, D; Gupta, R; Lee, C; Nachiappan, C, 2023)
"Osteoporosis is a prevalent condition characterized by low bone density and increased risk of fractures, resulting in a significant healthcare burden."( An, J; Liu, X, 2023)
"Osteoporosis is a common bone disorder characterized by reduced bone density and increased risk of fractures."( Fukaura, S; Iwasaki, Y, 2023)
"Osteoporosis is a major public health concern, which requires novel therapeutic strategies to prevent or mitigate bone loss."( Cho, IA; Hyun, M; Kim, JW; Koh, JT; Lee, BN; Park, SG; Piao, X; Ryu, JH; Song, JH; Wang, Z, 2023)
"Osteoporosis is a fatal bone-wearing malady and a substantial reason behind the impermanence of human life and economic burden."( Ali, A; Aqil, M; Jabi, B; Mujeeb, M; Sultana, N; Sultana, Y; Waheed, A; Yaqub Khan, M, 2023)
"Osteoporosis is a chronic bone disease affecting both men and women, but it is more prevalent in women."( Al-Khadher, MA; Elgzar, WT; Ibrahim, HA; Ismail, NI; Nahari, MH, 2023)
"Treatment of osteoporosis is conventional in mild to moderate stages but more complex in severe CKD because evidence about the efficacy and safety of anti-osteoporosis drugs is scant."( Lafage-Proust, MH, 2023)
"Osteoporosis is not well treated due to the difficulty of finding commonalities between the various types of it."( Ge, G; Geng, D; Gu, C; Wang, T; Wu, M; Xia, Y; Xiao, H; Yang, H, 2023)
"Disuse osteoporosis is known to be primarily caused by a lack of exercise."( Dai, Z; Jia, Y; Li, B; Liu, J; Lyu, F; Qi, H; Wang, L; Wang, Y; Xu, Y; Zhou, X; Zhu, H, 2023)
"Osteoporosis is a bone metabolic disease that usually causes fracture."( Chen, Y; Li, Y; Sui, X; Sun, X; Wang, Z, 2023)
"Osteoporosis is one of the major health problems characterized by decreased bone density and increased risk of fractures."( Chen, K; Chen, X; Gan, Z; Huang, J; Shang, X; Xu, M; Yuan, X, 2023)
"Osteoporosis is one of the skeletal degenerative diseases accompanied by bone loss and microstructure disruption."( Cao, Z; Chen, C; Du, R; Lei, H; Lu, Y; Qin, M; Song, Y; Wang, X; Wu, M; Zhang, C; Zhang, L; Zhou, J, 2023)
"Osteoporosis is a degenerative disease affecting millions of elderly people globally and increases the risk of bone fractures due to the reduced bone density."( Bai, J; Chu, PK; Gao, A; Ge, G; Geng, D; Liu, X; Wang, G; Wang, H; Wang, Q; Wang, W; Wu, Z; Yu, L, 2023)
"Osteoporosis is a systemic bone disease characterized by an imbalance in the relationship between osteoblasts, osteocytes, and osteoclasts."( Du, J; Li, X; Liu, B; Sun, K; Wang, Y; Xu, X; Zhang, X, 2023)
"Osteoporosis is a common bone disease characterized by loss of bone mass, reduced bone strength, and deterioration of bone microstructure."( Bao, X; Guo, J; Hao, D; Huang, D; Ji, J; Liu, J; Liu, S; Wang, X; Wei, L; Wu, S; Xia, Z; Ye, Y; Zhang, Y, 2023)
"Osteoporosis is a debilitating condition characterized by reduced bone mass and density, leading to compromised structural integrity of the bones."( Hong, S; Jung, HS; Kim, EJ; Kim, EY; Kim, JH; Kim, M; Lee, C; Lee, S; Park, H; Sohn, Y, 2023)

Context

ExcerptReference
"By convention, osteoporosis has been described in two categories: 1) primary (involutional or postmenopausal), and 2) secondary, in association with a wide variety of pathologic disorders."( Sandler, RB, 1978)
"Osteoporosis has been reported to complicate androgen deficiency in males."( Avioli, LV; Baran, DT; Bergfeld, MA; Teitelbaum, SL, 1978)
"Vertebral osteoporosis has recently been associated with RMO."( Banas, MP; Fallon, MD; Haddad, JG; Kaplan, FS, 1990)
"Osteoporosis has rarely been related to the use of cytostatic drugs."( Ott, H; Van Linthoudt, D, 1989)
"Most therapy for osteoporosis has been aimed at decreasing bone resorption and is capable of preventing further bone loss."( Chatterton, BE; Horowitz, M; Need, AG; Nordin, BE; Steurer, TA; Walker, CJ, 1986)
"Postmenopausal osteoporosis has a multifactorial pathogenesis related to decreases in bone mass, calcium intake, and circulating estrogen levels."( Tannenbaum, H, 1984)
"Primary osteoporosis has four clinical forms: postmenopausal, senile, juvenile, and idiopathic; these are differentiated from other forms of bone disease."( Wingate, L, 1984)
"Osteoporosis has been observed with chronic hypervitaminosis A but has not been established as a toxic effect of synthetic retinoid therapy in humans."( Abangan, DL; DiGiovanna, JJ; Reynolds, JC; Sollitto, RB; Steinberg, SM, 1995)
"Osteoporosis has long been considered a disease of the elderly; however, there is now a general agreement that predisposition begins in childhood and adolescence; thus, rational approaches to prevention of the disease should be started during childhood and adolescence."( Bonjour, JP; Carrié Fässler, AL, 1995)
"A new definition of osteoporosis has been proposed by an expert panel of the World Health Organization, in which cutoff diagnostic and therapeutic values are derived from bone mass measurements, leading to the practical idea of densitometric osteoporosis with or without fractures."( Alexandre, C, 1995)
"Since osteoporosis has been defined as "state of low bone mass", the bone mineral measurement has been utilized as a golden standard."( Aoki, C; Chen, JT; Hosoda, K; Shiraki, M, 1994)
"After osteoporosis has passed from acute to established phase, daily physical exercise and ergonomics, sufficient calcium and low dose of vitamin D supplements are useful."( Seitz, M, 1994)
"Osteoporosis has a major impact in the quality of life and the independence of the individuals, being the best treatment its prevention."( Forsbach, G; Santos, A, 1994)
"Osteoporosis has long been described in pregnant women who developed vertebral fractures in the last trimester or shortly after delivery without underlying disorders."( Epstein, S; Khovidhunkit, W, 1996)
"Osteoporosis has been extensively written about, yet the majority of articles deal only with the population of women patients."( Ade, R; Romeo, JH; Ybarra, J, 1996)
"Early diagnosis of osteoporosis has also substantial importance."( Ciesielska-Kopacz, N; Kos-Kudła, B; Pluskiewicz, W, 1998)
"Osteoporosis has been recognized as an important side effect of long-term and of pulsed steroid application after heart transplantation."( Abraham, C; Cremer, J; Demertzis, S; Graeter, T; Haverich, A; Nischelsky, J; Strüber, M; Wagenbreth, I, 1999)
"As osteoporosis has a strong genetic component we have also studied the COLIA1 and COLIA2 genes which code for the major protein of bone (type 1 collagen)."( Agnew, JE; Davies, K; Erten, S; Hanslip, JJ; Hoffbrand, AV; Jensen, C; Lalloz, M; Layton, M; Prescott, E; Raja, K; Tuck, S; Wonke, B, 1998)
"Osteoporosis has major medical and economic costs and consequences for society, yet the most effective strategies to pursue in reducing these costs and consequences are uncertain."( Chrischilles, E, 1996)
"Osteoporosis has been shown to be a relatively common complication of anorexia nervosa (AN)."( Bailer, U; de Zwaan, M; el Giamal, N; Kasper, S; Lennkh, C; Nagy, C; Strnad, A; Vytiska, E, 1999)
"Men with osteoporosis have been neglected in the past, and only a few therapeutic trials have been performed in men."( Dorst, A; Faber, H; Ringe, JD, 2001)
"Osteoporosis has been defined as "a progressive systemic disease characterized by low bone density and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture."( Sherman, S, 2001)
"As osteoporosis has garnered more attention there seems to be more attention than ever placed on the potential benefits of calcium and vitamin D."( Moyad, MA, 2002)
"Osteoporosis has become a major public health problem."( Coxam, V, 2003)
"Osteoporosis has been observed with chronic hypervitaminosis A, leading some authors to hypothesize that systemic retinoids may have an effect on bone mineral density."( Allen, GE; Dolan, OM; Irvine, AD; Irvine, D; McCarron, P; McMullen, EA, 2003)
"Osteopenia and osteoporosis have recently been described as complications of antiretroviral therapy in HIV-infected patients."( Doherty, SM; Thomas, J, 2003)
"The cause of this osteoporosis has been shown to be abnormal osteoclast proliferation, altering the process of bone remodeling."( Fukunaga, J; Ishiwari, Y; Kirino, S; Lee, YJ; Mizukawa, N; Nagai, N; Sawaki, K; Sugahara, T; Takagi, S; Tsujigiwa, H; Ueno, T; Yamaai, T; Yamachika, E, 2004)
"'Primary' osteoporosis has been associated with a high incidence of a renal acidification defect, incomplete renal tubular acidosis (iRTA)."( Chailurkit, LO; Domrongkitchaiporn, S; Pongchaiyakul, C; Rajatanavin, R; Stitchantrakul, W, 2004)
"Traditionally, osteoporosis has been regarded as a disease of postmenopausal women; nevertheless, although osteoporosis is more common in women than in men, osteoporosis in men is a frequent and a severe condition."( Kerschan-Schindl, K; Pietschmann, P, 2004)
"Obesity and osteoporosis have grave consequences for human health, quality of life, and even the efficiency of the labor force and economy."( Baile, CA; Della-Fera, MA; Hamrick, M; Nelson-Dooley, C, 2005)
"Most patients with osteoporosis have an identifiable cause of bone loss."( Birge, SJ; Wilkins, CH, 2005)
"Osteoporosis has had a significant public health impact, with many sufferers experiencing fractures."( Cooper, C, 2006)
"Osteoporosis has emerged as an important cause of morbidity in patients with thalassemia major."( Athanassiou-Metaxa, M; Garipidou, V; Harsoulis, F; Perifanis, V; Tziomalos, K; Vakalopoulou, S; Vyzantiadis, T, 2007)
"Osteoporosis has been successfully treated with anti-resorptive agents."( Nakamura, T, 2006)
"Osteoporosis has been linked with arteriosclerotic vascular diseases, suggesting that hypercholesterolemia or dyslipidemia may be a common pathogenetic factor underlying these diseases."( Fukao, A; Komatsu, Y; Majima, T; Matsumura, T; Nakao, K; Ninomiya, K; Satoh, N; Shimatsu, A, 2008)
"Steroid-induced osteoporosis has been reported to show reduced osteoblastic bone formation and accelerated osteoclastic bone resorption."( Amizuka, N; Li, M; Saito, T, 2008)
"Patients with osteoporosis have been shown to have decreased levels of vitamin K."( Alt, V; Drosse, I; Heiss, C; Hoesel, LM; Horas, U; Meyer, C; Schieker, M; Schnettler, R; Wehr, U; Wenisch, S, 2008)
"Osteoporosis has long been considered a health problem unique to older adults."( Binkovitz, L; Henwood, MJ, 2009)
"Osteoporosis has a major role in morbidity in these patients."( Ahmadpoor, P; Ghafari, A; Makhdoomi, K; Rahimi, E; Reisi, S; Sepehrvand, N, 2009)
"Osteoporosis has multi factor etiology."( Ryšavá, L; Stránský, M, 2009)
"Osteoporosis has become a worldwide health and social issue due to an aging population."( Ashley, JW; Feng, X; Jules, J, 2010)
"Osteoporosis has until now been considered to be a disease associated with abnormal calcium metabolism."( Li, GF; Li, K; Pan, YZ; Sirois, P; Xu, YJ, 2012)
"The treatment of osteoporosis has evolved from daily to yearly dosing thus facilitating compliance and effectiveness."( Duque, G, 2013)
"Postmenopausal osteoporosis has a big impact on health care expenses, with associated spending expected to double for osteoporosis by the year 2050."( Gosch, M; Kammerlander, C; Nicholas, JA, 2014)
"TN and osteoporosis have similar high-risk populations and a common influential factor - emotional stress - is also closed related to primary TN for calcitonin gene-related peptide and calcitonin."( Liu, L; Liu, N; Luo, E; Wang, H; Yang, Q, 2014)
"Osteoporosis has emerged as an important co-morbidity of HIV infection and a modest increase in fracture risk has been documented."( Compston, J, 2014)
"COPD and osteoporosis have some common risk factors."( Sanel, S; Sarıman, N; Sezgin, G; Solakoglu, C; Ugutmen, E, 2016)
"Patients with osteoporosis have a low bone mass resulting in an increased risk for bone fractures, morbidity and mortality."( Hadji, P; Kann, PH; Lange, U; Müller-Ladner, U; Tastan, Y; Tinneberg, HR, 2016)
"Osteoporosis has significant impact on healthcare costs and quality of life."( Emmerton, L; Lai, PS; Ng, CJ; Nik, J, 2016)
"Osteoporosis has been rarely described in the SS."( Audran, M; Bouvard, B; Insalaco, P; Legrand, E, 2017)
"Osteoporosis has a complex etiology and is considered a multifactorial polygenic disease, in which genetic determinants are modulated by hormonal, lifestyle, environmental, and nutritional factors."( Lee, HS; Park, T, 2018)
"Osteoporosis has brought about heavy socio-economic burden in the morbidity and medical expenses associated with osteoporosis treatment and various restrictions on behavior of their social roles."( Chen, S; Qiao, J; Sun, G; Xu, Y; Yu, T, 2018)
"Osteoporosis has been shown to intensify bone loss caused by periodontitis and both share common risk factors."( Jia, R; Jia, X; Li, Y; Luo, T; Miron, RJ; Wang, J; Wu, M; Xu, H; Yin, C; Zhang, Y, 2019)
"Type 2 diabetes osteoporosis has recently become a hot topic in the study of diabetic complications, but the specific mechanism of its development remains unclear."( Sun, J; Yang, B; Yang, MW; Zhang, WL; Zhao, W, 2019)
"Osteoporosis has become a worldwide problem as the population ages."( Li, G; Xue, F; Zhang, C; Zhu, B, 2019)
"Alveolar bone osteoporosis has attracted more and more attention because of its profound impact on stomatognathic function and treatment, but current treatments have not been targeted to alveolar bone and might even cause severe side effects."( Dai, Q; Gong, X; Hong, Y; Huang, X; Jiang, L; Jin, A; Qu, R; Xu, H; Yang, Y; Zhou, S, 2020)
"Clinical trials in osteoporosis have not demonstrated increases in osteonecrosis of the jaw or in atypical femoral fractures."( Black, DM; Cummings, SR; Eriksen, EF; Green, JR; Hosking, DJ; Lyles, KW; Reid, DM; Reid, IR; Russell, RGG; Trechsel, U, 2020)
"Osteoporosis has been recognized as a significant cause of disability in the elderly leading to heavy socioeconomic burden."( Chen, WL; Fang, WH; Huang, JW, 2023)
"Osteoporosis has influenced millions of people, especially postmenopausal women, which has become a big burden to the whole world."( Li, J; Li, X; Liu, W; Wang, S; Ye, X; Yu, Y; Zhang, D, 2023)
"Osteoporosis has been associated with greater clinical attachment loss in patients with periodontitis."( Bernardo, DV; De Marco, AC; de Moura, NB; Ferreira, CL; Jardini, MAN; Nunes, CMM; Santamaria, MP; Tricoly, TDS, 2022)
"Osteoporosis has been associated with several disorders; however, there have been only a limited number of reports on heroin-induced osteoporosis."( Chang, WN; Shih, YJ; Yang, SW, 2023)
"Osteoporosis has become a global public health problem, and the abnormal activation of osteoclasts is the key to the progression of osteoporosis and the key to both diseases lies in the osteoclasts."( Chen, H; Jiang, G; Lin, Z; Yang, Y; Zeng, X; Zheng, T, 2023)
"Osteoporosis has complex causes, one of which is related to the dysregulation of 5-hydroxytryptamine, a neurotransmitter closely associated with bone tissue metabolism."( Du, J; Li, X; Liu, B; Sun, K; Wang, Y; Xu, X; Zhang, X, 2023)
"Osteoporosis has a profound influence on public health."( Gao, JH; Li, J; Li, X; Qian, JJ; Sun, B; Wang, W; Wang, Z; Wei, WJ; Yang, JG; Zhang, P, 2023)

Actions

ExcerptReference
"Type I osteoporosis affects women 10-15 years after menopause and involves primarily trabecular bone while Type II, senile osteoporosis, results in hip fractures in both sexes."( Ullrich, I, 1991)
"Postmenopausal osteoporosis affects 25 to 50% of older women and increases the risk for vertebral, hip, and other fractures."( Gambrell, RD, 1986)
"Osteoporosis affects 15 to 20 million middle-aged and elderly persons, especially postmenopausal women who are susceptible to bone fractures."( Rusoff, LL, 1987)
"Osteoporosis affects more than 28 million Americans."( Bone, H; Greenspan, SL; Harris, ST; Miller, PD; Orwoll, ES; Rosen, CJ; Watts, NB, 2000)
"Osteoporosis affects about 10% of the total population but the prevalence among postmenopausal women is more than 30%."( Gera, I, 2002)
"Osteoporosis affects over 10 million Americans, including over 2 million men."( Mulligan, R; Sobel, S, 2005)
"Osteoporosis affects postmenopausal women and patients on glucocorticoid therapy."( Wallace, DJ, 2005)
"Osteoporosis affects both the organic and mineral phases of bone resulting in a decrease in resistance to fracture."( Chowdhury, S; German, MJ; Lawson, NS; Lyons, D; Moran, P; Pillay, I; Pollock, HM; Saunders, J; Towler, MR, 2007)
"Osteoporosis affects approximately 8 million women and 2 million men in the United States."( Galazka, SS; Jeremiah, MP; Sweet, JM; Sweet, MG, 2009)
"Osteoporosis affects approximately 9% of the population in Hungary resulting in about 100 000 osteoporotic fractures annually."( Lakatos, P, 2011)
"Although osteoporosis affects women of all ages, the impact is most pronounced in frail residents in long-term care."( Adams, D; Ferchak, M; Fiorito, G; Greenspan, S; Lee, C; Medich, D; Nace, D; Perera, S; Resnick, N; Saul, M; Zukowski, K, 2012)
"Osteoporosis affects the craniofacial and oral structures and has been associated with periodontal bone loss, tooth loss and reduced jaw bone mass."( Dias, R; Kulkarni, A; LeGeros, RZ; Lewis, K; Mijares, D; Tannous, S; Xi, Q; Yao, F, 2012)
"The osteoporosis affects 8."( Agrawal, NK; Sharma, B, 2013)
"Osteoporosis affects women more frequently than men; every second woman older than 50 years suffers from an osteoporotic fracture, frequently a vertebral fracture."( Alt, V; Böcker, W; Elkhassawna, T; Govindarajan, P; Heiss, C; Hemdan, NY; Lips, KS; Schlewitz, G; Schliefke, N; Schnettler, R; Thormann, U; Zahner, D, 2013)
"Osteoporosis affects 200 million people worldwide and places an enormous economic burden on society."( Guo, S; Guo, W; Liu, J; Luo, E; Ma, X; Shen, G; Tang, C; Wu, X; Xie, K; Yan, Y, 2013)
"Osteoporosis affected women earlier than men in this study."( Postic, SD, 2013)
"Disuse osteoporosis affects men and women, but there is lack of awareness and relevant pharmaceutical studies for this condition."( Fung, KP; Hung, LK; Ko, CH; Lau, CB; Lau, CP; Leung, PC; Siu, WS, 2013)
"Postmenopausal osteoporosis affects millions of women, being estrogen deficiency the key factor in the pathogenesis of involutional osteoporosis."( Gambacciani, M; Levancini, M, 2014)
"BACKGROUND Osteoporosis affects millions of postmenopausal women worldwide."( Drosos, G; Kapetanou, A; Kazakos, K; Kitsikidou, G; Kiziridis, G; Kotsianidis, I; Papoutselis, M; Rechova, KV; Spanoudakis, E; Tilkeridis, K; Tousiaki, NE; Ververidis, A, 2019)
"Osteoporosis affects a segment of the population in which Chronic Kidney Disease is also greatly represented."( Alessandrello, I; Aprile, G; Distefano, G; Ficara, V; Galeano, D; Giglio, E; Granata, A; Musso, S; Musumeci, S; Pocorobba, B; Sessa, C; Zuppardo, C, 2019)
"Osteoporosis is affecting the health of postmenopausal women in the world."( Jie, J; Li, W; Wang, G; Xu, X, 2021)
"Osteoporosis affects millions worldwide and is often caused by osteoclast induced bone loss."( Arandjelovic, S; Cambré, I; Ceroi, A; Conrads, TP; Elewaut, D; Onengut-Gumuscu, S; Perry, JSA; Ravichandran, KS; Shankman, LS; Smirnov, I; Walk, SF; Zhou, M, 2021)
"Osteoporosis affects mostly postmenopausal women, leading to deterioration of the microarchitectural bone structure and low bone mass, with an increased fracture risk with associated disability, morbidity and mortality."( Betsch, M; Colarossi, G; Eschweiler, J; Maffulli, N; Migliorini, F; Tingart, M, 2021)
"Osteoporosis affects millions of people worldwide."( Agwaya, MS; Choi, G; Hwang, KS; Kan, H; Kang, Y; Kim, YG; Komakech, R; Kyeyune, GN; Lee, J; Matsabisa, MG; Okello, D; Omujal, F; Shim, KS; Song, JH; Yang, S; Yim, NH, 2022)
"Osteoporosis affects approximately 10% of the population worldwide."( Han, X; Li, S; Wang, T; Wang, X; Yi, C, 2022)

Treatment

ExcerptReference
"The aetiology and treatment of the osteoporosis and the periosteal reactions remain obscure."( Long, RG; Wills, MR, 1978)
"The efficacy of long term treatment of senile osteoporosis by low doses of calcitonin was established using five parameters of calcium kinetics and a quantitative pain scale."( Coutris, G; Milhaud, G; Talbot, JN, 1975)
"The results suggest that fluoride treatment of osteoporosis can be continued beyond one year."( Fuchs, C; Hauswaldt, C; Hesch, RD; Köbberling, J; Unger, KO, 1977)
"Even for the treatment of osteoporosis, there may be safer alternative therapies."( , 1976)
"In Paget's disease and fluoride-treated osteoporosis a thickening of rarefied trabeculae in both was associated in Paget's disease only with an increase in the trabecular number and the transformation of a discontinuous arrangement into a more continuous network."( Aaron, JE; de Vernejoul, MC; Kanis, JA, 1992)
"Cyclical treatments of osteoporosis utilizing a skeletal Activator of bone remodelling, and sequential therapy with a Depressor to selectively block the resulting phase of osteoclastic resorption have been dubbed 'ADFR' therapy; there is usually a treatment Free interval while the activated bone multicellular units complete the remodelling cycle before the protocol is Repeated."( Drost, DJ; Fraher, LJ; Hodsman, AB; Steer, BM, 1991)
"Fluoride has been used for the treatment of osteoporosis since 1961, because it increases trabecular bone mass in the spine and may be effective in the treatment of spinal osteoporosis."( Inkovaara, JA, 1991)
"Clearly, successful treatment of osteoporosis remains an unsolved problem."( Lee, JR, 1991)
"GH was used to treat osteoporosis in a few clinical trials."( Netelenbos, JC; van der Veen, EA, 1990)
"The decisive progress in the treatment of osteoporosis is to be expected from an essentially improved and pathophysiologically oriented differential diagnosis and the resulting differential therapy."( Abendroth, K, 1990)
"When deciding about treatment of osteoporosis in the elderly, it should be noted that few studies have included patients over 75 years of age and that prevention of bone loss is more effective than restoration of lost bone."( Meuleman, J, 1989)
"Thirteen patients did not have any treatment for osteoporosis and served as a patient control group."( Yamada, H, 1989)
"It has proved worthwhile to treat osteoporosis simultaneously in two ways."( Dambacher, MA, 1988)
"Recently, fluoride has been used in the treatment of osteoporosis in an attempt to rebuild bone lost due to this disease."( Cheng, PT; Grynpas, MD, 1988)
"Report on 3 female patients who, after treatment of an osteoporosis with sodium fluoride, have developed a skeletal fluorosis."( Eisengarten, K; Leuschke, W; Schmidt, CW, 1986)
"Fluoride treatment of osteoporosis results in tangible improvement, but its pharmacological basis is incompletely understood and therapeutic doses are not tolerated indefinitely or by all patients."( Barmes, DE; Schamschula, RG, 1981)
"It is concluded that treatment of osteoporosis with 1 alpha-OHD3 and calcium is ineffective and potentially dangerous because it frequently causes hypercalcemia."( Alhava, EM; Aro, A; Hoikka, V; Karjalainen, P; Rehnberg, V, 1980)
"26 women were treated for osteoporosis with 40 mg of sodium fluoride twice a day (equivalent 36 mg of fluorine) for a longer period."( Börner, W; Eichner, R; Henschler, D; Köhler, W; Moll, E, 1981)
"New approaches to treatment of osteoporosis will emerge as our understanding of the pathogenesis increases."( Pilbeam, CC; Prestwood, KM; Raisz, LG, 1995)
"The drug treatment of osteoporosis has to be accompanied by a proper pain therapy as well as a physiotherapeutic, orthopedic and psychososical care."( Geidel, H, 1995)
"The use of 1,25(OH)2D for treatment of osteoporosis in individuals with adequate nutrition and sunlight exposure may require somewhat higher than physiologic doses to be effective."( Bikle, DD, 1994)
"Calcium and RKH were effective in treating osteoporosis and they could recover the level of estrogen and 1,25-(OH)2-D3 to normal state, the effect of RKH was better than that of calcium."( Li, E; Liu, HD; Tong, XX, 1993)
"The efficacy of treatments for osteoporosis does not become evident when evaluated by fracture incidence (FI)."( Burckhardt, P; Burnand, B, 1993)
"Interest in vitamin D treatment for osteoporosis has recently been revived because of the focus in various parts of the world on the elderly population, which is predominantly vitamin D deficient, in addition to postmenopausal osteoporosis due to estrogen withdrawal, which has been the central theme of osteoporosis research for many years."( Fujita, T, 1996)
"Long-term heparin treatment causes osteoporosis through an as yet undefined mechanism."( Andrew, M; Deschamps, P; Hirsh, J; Muir, JM; Shaughnessy, SG; Weitz, JI; Young, E, 1996)
"Many new agents for the treatment of osteoporosis are being examined."( Bellantoni, MF, 1996)
"The use of 1 alpha-OH-D3 for the treatment of osteoporosis in Canada cannot be supported without larger and longer randomized, controlled clinical trials."( Hanley, DA; Hogan, DB; Jones, G; Yendt, E, 1996)
"Therapies to prevent bone loss and treat established osteoporosis are uncommonly utilized in glucocorticoid-treated patients with end-stage pulmonary disease."( Addesso, V; Donovan, D; Jorgesen, B; McGregor, C; Papadopoulos, A; Schulman, L; Shane, E; Silverberg, SJ; Staron, RB, 1996)
"Sodium fluoride has been used to treat established osteoporosis for nearly 30 years."( Coggon, D; Cooper, C; Hillier, S; Inskip, H, 1996)
"Unique features of treatment for osteoporosis in Japan include rare use of estrogen replacement therapy, common use of vitamin D derivatives (especially 1alpha(OH) vitamin D) without notable side effects, and use of calcitonin almost exclusively in a low-dose intermittent regimen (20 U/week)."( Fujita, T, 1996)
"We conclude that in the treatment of osteoporosis, NaF has a protective effect against vertebral and nonvertebral fractures, does not increase the risk of femoral fractures, but has a higher incidence of untoward symptomatology."( Armadans, L; Farrerons, J; Guañabens, N; López-Navidad, A; Renau, A; Rodríguez de la Serna, A; Vaqué, J; Yoldi, B, 1997)
"Agents for prevention or treatment of osteoporosis must now be tested in a large animal species that exhibits bone remodeling."( Jerome, CP; Lees, CJ; Turner, CH, 1997)
"There is no established treatment for osteoporosis in men, a common and disabling condition the incidence of which is increasing rapidly."( Anderson, FH; Francis, RM; Peaston, RT; Wastell, HJ, 1997)
"The paper concerns the nontraditional treatment of osteoporosis using endogenous substances regulating bone metabolism, and also new drugs."( Kanceva, RL; Zofková, I, 1997)
"Testosterone is an effective treatment for male osteoporosis associated with hypogonadism and is also promising in the treatment of osteoporosis in aged eugonadal males."( da Silva, JA; Porto, A, 1997)
"The number of agents for the treatment of osteoporosis has increased over the past few years allowing more and more differentiated therapy."( Koike, T; Orito, Y; Satoh, T; Yoshida, G, 1998)
"Alendronate is indicated for the treatment of osteoporosis in post-menopausal women."( Freemantle, SN; Mackay, FJ; Mann, RD; Pearce, GL; Wilton, LV, 1998)
"Fluorides salts are used in the treatment for osteoporosis for 30 years, since their anabolic action on trabecular bone is well documented, but safety and efficacy of this treatment is still debated."( Bohatyrewicz, A, 1998)
"Fluoride has been used in the treatment for osteoporosis for more than 30 years but its use is still controversial."( Lips, P, 1998)
"For the treatment of osteoporosis the best result could be obtained with a combined treatment with monofluorophosphate, stimulating osteoblasts and production of new bone, and a bisphosphonate, which simultaneously inhibits osteoclasts and bone resorption."( Duursma, SA; Raymakers, JA, 1998)
"Drugs for treating osteoporosis include hormone replacement therapy, alendronate, and nasal calcitonin."( O'Connell, MB, 1999)
"Cost/benefit analyses of alendronate treatment for osteoporosis should include costs of treating ARD."( Ettinger, B; Pressman, A; Schein, J, 1998)
"Evidence of the efficacy of treatment for osteoporosis is shown by a reduced probability of fracture."( Juby, A, 1999)
"Good evidence indicates that adequate treatment of osteoporosis can prevent fractures and thus reduce associated morbidity and mortality among vulnerable elderly people."( Juby, A, 1999)
"Exogenous estrogen can prevent and treat osteoporosis and is available in several delivery routes."( Meiner, SE, 1999)
"The longterm benefits of rhGH in the treatment of osteoporosis remain unclear."( Ansell, BM; Davies, UM; Preece, M; Reeve, J; Rooney, M; Woo, PM, 2000)
"One class of agents used to treat osteoporosis is the bisphosphonates, which inhibit bone resorption, cause an increase in bone mineral density and reduce the risk of future fractures caused by aging, estrogen deficiency and corticosteroid use."( Bone, H; Greenspan, SL; Harris, ST; Miller, PD; Orwoll, ES; Rosen, CJ; Watts, NB, 2000)
"Most CR investigated and treated osteoporosis themselves, 13% referred to other specialists for investigation, and 22% referred for treatment."( Adachi, JD; Bellamy, N; Campbell, J; Flynn, J; Pope, JE; Soucy, E; Sutton, E, 2000)
"Active vitamin D drugs are used for the treatment of osteoporosis in a number of countries, including Japan."( Ikeda, K; Ogata, E, 2000)
"The goal of drug treatment of osteoporosis is to prevent fractures."( Halbekath, J, 2000)
"The rate of diagnosis and treatment of osteoporosis in this patient group is unknown."( Bogoch, ER; Hajcsar, EE; Hawker, G, 2000)
"Possible treatment of osteoporosis in course of male hypogonadism is discussed."( Jóźków, P; Medraś, M, 2000)
"Studies of untreated and treated osteoporosis in postmenopausal women have also contributed to this knowledge and have provided unequivocal evidence for the potential of high-dose estrogen therapy to have anabolic skeletal effects."( Compston, JE, 2001)
"Drug treatments for osteoporosis are intended to inhibit bone resorption, reduce the rate of bone turnover, and increase bone mass."( Baran, D, 2001)
"In addition to treating osteoporosis, PTHs may be used to promote fracture healing, to restore bone loss in immobilized patients, or following excessive glucocorticoid or prolonged spaceflight, and to treat psoriasis."( Morley, P; Whitfield, JF; Willick, GE, 2001)
"We discuss this approach of treating osteoporosis with corticoids and immunosuppressors according to the present knowledge of bone biology."( Fassi, J; Plantalech, L, 2001)
"The diagnosis and treatment of osteoporosis is an important aspect of gynecologic training and practice."( Jennings, JC; Kauffman, RP; Overton, TH; Shiflett, M, 2001)
"Recent additions to the treatment of osteoporosis with potent bone active drugs produce an even greater need for calcium and total nutrition for restoration of lost bone."( Dowd, R, 2001)
"Specific treatment against osteoporosis was in most cases instituted secondary to osteoporotic complications."( Gudbjornsson, B; Gudjonsson, FV; Juliusson, UI, 2002)
"One of the major side-effects of this treatment is osteoporosis, which may result in the increased occurrence of fractures."( Boomsma, MM; Karsijns, M; Kramer, AB; Piers, DA; Stegeman, CA; Tervaert, JW, 2002)
"The majority of treatment for osteoporosis has focused on secondary and tertiary strategies that attempt to preserve acquired adult bone mass."( Durst, ES, 2000)
"Raloxifene a related SERM is used to treat and prevent osteoporosis with the potential beneficial side effect of preventing breast cancer."( Bentrem, DJ; Craig Jordan, V, 2002)
"Issues relating to the treatment of the osteoporosis as well as the lymphoma arise in patients that present in this way."( Atoyebi, W; Brown, M; Hatton, C; Littlewood, TJ; Wass, J, 2002)
"HRT is effective for treating osteoporosis, with improvement in bone density and reduction in vertebral fractures."( Ames, R; Clearwater, J; Evans, MC; Gamble, G; Reid, IR; Wu, F, 2002)
"For the drug treatment of osteoporosis in the first years after menopause, oestrogens, tibolone and raloxifene may be used."( Pols, HA; Wittenberg, J, 2002)
"Antiresorptive therapy are usual treatment of osteoporosis, but they prevent no more than 40 or 60% of osteoporotic fracture."( Chaouat, D, 2002)
"Alendronate has been approved for treatment of osteoporosis in men, and other treatments for men are under evaluation."( Deal, C; Srivastava, M, 2002)
"Up to 80-90% of patients with treatment-requiring osteoporosis are not receiving specific treatment."( Begerow, B; Hinz, C; Minne, HW; Pfeifer, M; Pollähne, W, 2002)
"Alendronate is an agent for the treatment of osteoporosis that has established safety with regards to bone quality since it neither inhibits bone calcification nor influences fracture healing in chronic administration."( Komatsu, S; Ohta, T; Tokutake, N, 2002)
"New drugs to treat osteoporosis, along with two new minimally invasive surgical procedures, are important options for preventing vertebral compression fractures and treating severe back pain and disability."( Mazanec, DJ; Mompoint, A; Podichetty, VK; Potnis, A, 2003)
"RSD is available for the treatment of osteoporosis."( Fukunaga, M, 2003)
"The aim of prevention and treatment of osteoporosis is to prevent the occurrence of future fractures."( Christodoulou, C; Cooper, C, 2003)
"Bisphosphonate drugs for treating osteoporosis are excreted by the kidney."( Cavanaugh, PF; Connelly, JE; Gordon, MJ; Klawansky, S; Komaroff, E; Mitchell, DY; Ross, SD, 2003)
"BSHXL could prevent and treat osteoporosis in male rats induced by DM."( Chen, K; Hou, L; Lu, D; Ma, X; Peng, K; Wang, T; Zhang, R; Zhu, X, 2003)
"In the treatment of osteoporosis, the tolerance of oral bisphosphonates is often low."( Burckhardt, P; Burnand, J; Fatio, S; Lamy, O; Pache, I; Sandini, L, 2003)
"The diagnosis and treatment of osteoporosis have changed dramatically in the last decade."( Black, DM; Greenspan, SL; Rosen, CJ, 2004)
"Diagnosis and treatment of osteoporosis are focused on demineralisation but bone mineral density is not directly correlated with bone strength."( Liverneaux, P, 2004)
"PE is effective in preventing and treating osteoporosis in ovariectomized rats."( Wang, YJ; Xu, JL; Zhang, J, 2004)
"For example, treatments for osteoporosis may have unanticipated effects on vascular calcification; the converse also applies."( Abedin, M; Demer, LL; Tintut, Y, 2004)
"This may lead to new strategies for the treatment of osteoporosis and the low turnover bone disease of some dialysis patients."( Bushinsky, D; Silver, J, 2004)
"The level of recognition and treatment of osteoporosis is not well characterized in primary care."( Clapham, S; Eisman, J; Kehoe, L, 2004)
"Subjects were patients that were treated for osteoporosis at Department for physical medicine and rehabilitation in Clinical hospital Dubrava."( Badovinac, O; Delija, A; Sakić, D; Sakić, VA, 2004)
"In recent years, treatments for osteoporosis have been developing rapidly, and many of these research results have been reported."( Nakamura, T, 2004)
"There is no well-established treatment for osteoporosis in male patients with leprosy, because no clinical trials have examined the efficacy of treatment on bone mineral density (BMD) or fracture incidence in patients with leprosy."( Ando, K; Higashi, M; Ichinose, H; Kanaji, A; Nakagawa, M; Namisato, M; Sakamaki, T; Yamada, H; Yato, Y, 2005)
"This may suggest new approaches to the treatment of male osteoporosis."( Alexandre, C, 2005)
"In this study of elderly men and women treated for osteoporosis (n=5,313), 60."( Dukas, L; Schacht, E; Stähelin, HB, 2005)
"We succeeded in treating osteoporosis in SAMP6 mice after the onset of this disease, using a newly developed method of bone marrow transplantation (BMT): Allogeneic bone marrow cells obtained from normal mouse strains were directly injected into the bone marrow cavity of irradiated SAMP6 mice (intra-bone marrow BMT [IBM-BMT])."( Baba, S; Hisha, H; Ichioka, N; Iida, H; Ikehara, S; Inaba, M; Mizokami, T; Taira, M; Takada, K; Ueda, Y; Wang, X, 2006)
"Pharmacological treatment of osteoporosis is based mainly on antiresorptive agents."( Alonso, G; Fernández-García, D; Muñoz-Torres, M, 2005)
"The bisphosphonates, widely used in the treatment of osteoporosis, act by inhibiting bone resorption."( Fleming, A; Goldsmith, P; Sato, M, 2005)
"Finally, 52% of patients had stopped treatment given for osteoporosis after a mean period of 1."( Bona, E; Carnevale, V; Minisola, S; Nieddu, L; Piemonte, S; Romagnoli, E; Scillitani, A, 2006)
"Drug treatment of osteoporosis is based on the knowledge of mechanisms of bone turnover and the manipulation of the cellular components of bone turnover in terms of recruitment, activation and apoptosis of the cells involved."( Geusens, P; Reid, D, 2005)
"However, the identification and treatment of osteoporosis in these high-risk patients are widely reported to be inadequate."( Beaton, DE; Bogoch, ER; Elliot-Gibson, V; Jamal, SA; Josse, RG; Murray, TM, 2006)
"Only one patient received advice or treatment regarding osteoporosis at the time of fracture."( Beringer, T; Finch, M; Keegan, D; Kelly, J; McKane, R; McNally, C; McQuilken, M; Taggart, H; Whithead, E; Wright, S, 2007)
"Vitamin K2 is widely used for the treatment of osteoporosis in Japan."( Iwamoto, J; Sato, Y; Takeda, T, 2006)
"Osteoporosis results in fractures and treatment of osteoporosis has been shown to reduce risk of fracture particularly in those who have had a history of fracture."( Jones, TJ; Petrella, RJ, 2006)
"The frequency of medication use for the treatment of osteoporosis including estrogen replacement therapy, bisphosponates, calcitonin, calcium and vitamin D therapy was determined on admission, at 6 weeks post discharge and one year following discharge."( Jones, TJ; Petrella, RJ, 2006)
"Icariin could effectively prevent and treat osteoporosis and promote the bone formation."( Chen, A; Guo, F; Xiao, Q, 2005)
"After 1 year of treatment, osteoporosis completely recovered in six patients (28."( Abaci, A; Bober, E; Büyükgebiz, A; Unal, E, 2006)
"In the medical treatment of osteoporosis and metabolic osteopathies bisphosphonates could be rightly denoted as groundbreaking."( Fassbender, WJ; Kurth, A; Stumpf, UC, 2006)
"Bisphosphonates form the mainstay of treatment in osteoporosis; however, current adherence with therapy is inadequate."( Burke, MS; Simonelli, C, 2006)
"There is no well-established treatment for osteoporosis in male patients with leprosy, because no clinical trials have examined the efficacy of treatment on bone mineral density (BMD) or fracture incidence in such patients."( Ando, K; Higashi, M; Kanaji, A; Namisato, M; Nishio, M; Yamada, H, 2006)
"Strontium ranelate is a new treatment for osteoporosis that results in large increases in BMD, much of which is an artefact caused by high bone strontium content."( Blake, GM; Fogelman, I, 2006)
"In 2002, Adequate Treatment of Osteoporosis (A-TOP) Research Group was organized to obtain the evidence for treatment of osteoporosis in Japan."( Kuroda, T; Miyakawa, N; Orimo, H, 2006)
"The most important goal in the treatment of osteoporosis is fracture prevention."( Inoue, D; Matsumoto, T, 2006)
"Prompt diagnosis and treatment of osteoporosis reduce refracture rates."( Cho, T; Freedman, BA; Kuklo, TR; Nesti, LJ; Potter, BK, 2007)
"Patients undergoing treatment for osteoporosis have reported hardening of their fingernails."( Chowdhury, S; German, MJ; Lawson, NS; Lyons, D; Moran, P; Pillay, I; Pollock, HM; Saunders, J; Towler, MR, 2007)
"Fifty-four patients were treated for osteoporosis-related fractures and 5 had malignant disease."( Kobayashi, N; Matsusako, M; Numaguchi, Y; Rahman, M; Saida, Y; Uemura, A, 2007)
"But many physicians concerning treatment of osteoporosis had been interested in increase of bone mineral density, decrease of fracture rate and improvement of bone quality, instead of relief of the pain."( Hayashi, Y, 2007)
"They are indicated for the treatment of osteoporosis."( Beirne, JC; Khosa, AD; Nayyar, MS, 2007)
"Bisphosphonates have been used to treat osteoporosis for more than ten years."( Choo, KS; Kim, JS; Ryu, JH; Won, JH; Yang, KH; Yoon, HK, 2007)
"Long-term treatment of osteoporosis is required for optimal efficacy, but adherence to therapy is suboptimal with daily and weekly oral bisphosphonates."( Babic-Naglic, D; Curkovic, B; Grazio, S; Kehler, T, 2008)
"To investigate alendronate for treating osteoporosis in men."( Davison, KS; Olszynski, WP, 2008)
"Most drugs for treating osteoporosis seem safe for patients with mildly decreased renal function (glomerular filtration rate [GFR] 60-90 ml/min)."( Eiken, PA; Vestergaard, P, 2008)
"To effectively treat osteoporosis and other bone-loss disorders, small compounds that potently induce bone formation are needed."( Chung, UI; Hojo, H; Igawa, K; Ikeda, T; Komiyama, Y; Lichtler, AC; Nakajima, K; Ohba, S; Takato, T; Woo, JT; Yano, F; Yonezawa, T, 2008)
"Vitamin K2 has been approved for the treatment of osteoporosis in Japan since 1995."( Ishida, Y, 2008)
"Current approved medical treatments for osteoporosis reduce fracture risk to a greater degree than predicted from change in BMD in women with postmenopausal osteoporosis."( Busse, C; Cheng, Z; Lane, NE; Ritchie, RO; Yao, W; Zimmermann, EA, 2009)
"To describe new agents for the treatment of osteoporosis, discuss a conceptual framework of agents that are antiresorptive or anabolic, and review pathways that affect bone turnover and steps in those pathways that are targets for new therapeutic agents."( Deal, C, 2009)
"Trends in the use of different treatments for osteoporosis among the civilian, ambulatory U."( Blalock, SJ; Farley, JF, 2009)
"Pharmacomedical treatments for osteoporosis were applied."( Gulan, G; Novak, S; Sestan, B; Tudor, A; Vrbanić, TS, 2008)
"Diagnosis and treatment of osteoporosis are evolving from BMD (bone mineral density) dependent manner to bone quality conscious manner."( Azuma, K, 2009)
"Individual patients who are treated for osteoporosis in clinical practice commonly differ from subjects enrolled in these clinical trials according to confounding factors that include age, sex, comorbidities, compliance, and persistence."( Lewiecki, EM, 2010)
"For the treatment of osteoporosis, anti-resorptive agents including bisphosphonates and raloxifene are widely used."( Endo, I; Matsumoto, T, 2010)
"Diagnosis and treatment of osteoporosis are often delayed especially in men, because the concept of male osteoporosis has not been fully penetrated."( Kawate, H; Takayanagi, R, 2010)
"The efficacy of treatments for osteoporosis can be evaluated using these techniques."( Ferrari, S, 2010)
"Women undergoing treatment for osteoporosis require long-term dosing therapeutic regimens, that offer no symptomatic relief, and may cause side effects."( Altavilla, D; Bitto, A; D'Anna, R; Granese, R; Irrera, N; Marini, H; Minutoli, L; Polito, F; Squadrito, F, 2010)
"The indication for BP was prevention or treatment of osteoporosis in 11 cases and breast with bone metastases in one case."( Barrier, A; Descroix, V; Goudot, P; Lescaille, G; Rigolet, A; Ruhin, B, 2010)
"Therapies to treat osteoporosis remain underutilized and minimally evaluated in frail elderly patients."( Abellan Van Kan, G; Boonen, S; Gillette-Guyonnet, S; Rolland, Y; Roux, C; Vellas, B, 2011)
"The imperative to treat osteoporosis appears to be greatest in frail patients since similar relative risk reductions would avert more fractures in frail than in non-frail elderly patients."( Abellan Van Kan, G; Boonen, S; Gillette-Guyonnet, S; Rolland, Y; Roux, C; Vellas, B, 2011)
"Poor persistence to treatment of osteoporosis should consequently be acknowledged as an important and costly health problem, and be taken into account when evaluating osteoporosis interventions."( Landfeldt, E; Lundkvist, J; Ström, O, 2011)
"Undertreatment of osteoporosis is common, even for high-risk patients."( Arora, T; Becker, DJ; Colon-Emeric, C; Curtis, JR; Delzell, E; Kilgore, ML; Matthews, RS; Morrisey, MA; Saag, KG; Safford, MM; Taylor, A; Warriner, A, 2010)
"Prevention and treatment of osteoporosis in COPD should therefore be based on population specific risk assessments which combine measures of bone mineral density and clinical factors."( Decramer, M; Janssens, W; Lehouck, A; Troosters, T; van Remoortel, H, 2010)
"In order to improve the treatment of osteoporosis, identification of anabolic and orally available agents with minimal side effects is highly desirable."( Chen, D; Huang, J; Shi, Q; Tang, DZ; Wang, YJ; Yang, F; Yang, Z, 2011)
"Primary exposure was medical treatment for osteoporosis, and the outcome was all-cause mortality."( Juntunen, M; Lüthje, P; Nurmi-Lüthje, I; Sund, R, 2011)
"Early prevention and treatment of osteoporosis in COPD is, therefore, important and should be based on integrated risk assessment tools such as FRAX, which take bone mineral density, history of fragility fractures, and population-specific clinical factors into account."( Boonen, S; Decramer, M; Janssens, W; Lehouck, A, 2011)
"The most common treatment of osteoporosis is N-containing bisphosphonates, a class of non-hydrolyzable pyrophosphate analogs."( Leong, WF; Li, B; Ling Chau, JF; Wang, X, 2011)
"The more recent guidelines for treating osteoporosis now include men, but the recommendations for screening and treatment are not necessarily gender specific."( Das, S; Gates, BJ, 2011)
"Intense treatment for osteoporosis is warranted in diabetics who have other established fracture risks such as those with prevalent fractures or postmenopausal state."( Okazaki, R, 2011)
"In order to effectively treat osteoporosis and other bone-loss disorders, small compounds that could induce bone formation are needed."( Du, J; Jiang, YP; Peng, C; Qin, LP; Rahman, K; Ran, X; Wei, YJ; Zhang, H, 2011)
"Due to the recent advances in the treatment of osteoporosis, clinicians can utilize many kinds of drugs to prevent fractures."( Shiraki, M, 2011)
"The mainstay of the treatment of osteoporosis is the bisphosphonate group that includes effective anti-resorptive compounds mitigating bone loss and fragility."( Lakatos, P, 2011)
"Current treatments for osteoporosis are associated with various side effects and do not prevent the age-related decrease in osteoblast number."( Chang, K; Cheong, M; Deng, W; Hsiao, W; Lam, G; Lee, C; Liu, H; Tsai, C; Wang, M; Wu, C, 2011)
"In addition to systemic treatment, osteoporosis may be treated topically by incorporating calcium and phosphate into the bone."( Boda, K; Gomez, I; Pap, L; Szabó, A; Szekanecz, Z, 2012)
"Prevention and treatment for osteoporosis in the transplant recipient are also discussed."( Borba, VZ; Custódio, MR; Kulak, CA; Kulak, J, 2012)
"Drugs used for the prevention and the treatment of osteoporosis exert various favourable and unfavourable extra-skeletal effects whose importance is increasingly recognized notably for treatment selection."( Bergmann, P; Body, JJ; Boonen, S; Devogelaer, JP; Gielen, E; Goemaere, S; Kaufman, JM; Reginster, JY; Rozenberg, S, 2012)
"Bisphosphonates are used widely to treat osteoporosis in adults and are used increasingly for primary and secondary osteoporosis in children."( Briody, J; McQuade, M; Munns, CF; Ooi, HL, 2012)
"Current methods of bone defect treatment for osteoporosis are not always satisfactory."( Cao, L; Dai, K; Fan, Q; Gan, Y; Liu, G; Tang, T; Yang, F; Zhang, X, 2012)
"Persistence and compliance during the treatment of osteoporosis were found to be insufficient."( Boeckhoff, J; Hadji, P; Kostev, K; Kyvernitakis, I; Ziller, V, 2012)
"The methods used in treatment of osteoporosis induced by glucocorticosteroids are not effective enough."( Kaczmarczyk-Sedlak, I; Rotko, K; Sedlak, L; Zych, M, 2012)
"Most medication used for the treatment of osteoporosis is antiresorptive; however, strontium ranelate (Sr) therapy in postmenopausal women has shown a double effect on resorption and bone formation."( Berköz, M; Comelekoglu, U; Eroglu, P; Sagír, O; Yalin, S, 2012)
"Undertreatment of osteoporosis was common in rural patients."( Ang, WM; Lai, MM; Larke, AB; McGuiness, M, 2012)
"Both RAL and RIS could treat osteoporosis in ORX rats; they reduced bone turnover markers and maintained BMD."( El-Abd, EE; El-Ashmawy, NE; El-Bahrawy, HA; Haggag, AA; Khedr, NF, 2013)
"Most drugs for treating osteoporosis seem safe in terms of affecting renal function for patients with mildly to moderate decreased renal function."( Eiken, PA; Vestergaard, P, 2012)
"The use of bisphosphonates for the treatment of osteoporosis is increasing."( De Smet, L; Degreef, I; Didden, K; Sciot, R; Vandenberghe, L, 2012)
"Clinically, Sr was applied for treatment of osteoporosis, composite biomaterials in tissue engineering, and treatment of bone tumors and bone metastases."( Lei, Y; Li, L; Meng, Z, 2012)
"Prevention or treatment of osteoporosis should be considered in all patients who received a daily dose of at least 7."( Briot, K; Roux, C, 2013)
"Specific agents used for treatment of osteoporosis include bisphosphonates, calcitonin, hormonal therapy, and raloxifene."( Carey, EJ; Yadav, A, 2013)
"Alendronate is commonly used in the treatment of osteoporosis and other bone diseases."( Bee, J; Hanna, J; Sataloff, RT, 2012)
"Current treatments for osteoporosis are limited by lack of effect on cortical bone, side effects, and, in some cases, cost."( Hamilton, CJ; Jamal, SA; Reid, LS, 2013)
"Older hypogonadal males should be treated in cases of osteoporosis, reduced muscle strength and increased risk of falling."( Mosekilde, L; Rejnmark, L; Vestergaard, P, 2013)
"The guidance given in treating osteoporosis can potentially enhance adherence."( Chen, SH; Cheng, TT; Hsu, CY; Su, BY; Yang, TS; Yu, SF, 2013)
"Raloxifene is a drug for the treatment of osteoporosis and for the prevention of estrogen receptor-positive breast cancer because it guarantees a safety profile on the endometrium."( Ancona, E; Berretta, R; Bertocco, A; Capobianco, G; D'Antona, D; Di Gangi, S; Gizzo, S; Nardelli, GB; Noventa, M; Patrelli, TS; Saccardi, C; Vacilotto, A, 2013)
"Compliance of oral alendronate to treat osteoporosis in elderly male patients is poor."( Fang, FS; Hou, HR; Jiang, Y; Li, CL; Liu, MY; Pei, Y; Pi, HY; Yan, YF, 2013)
"Pharmaceutical countermeasures to treat disuse osteoporosis are rarely studied."( Fung, KP; Hung, LK; Ko, CH; Lau, CB; Lau, CP; Leung, PC; Siu, WS, 2013)
"The first use of zoledronic acid in the treatment of osteoporosis appears high incidence of APR."( Chen, DC; Chen, Y; Guo, YH; Liu, T; Lu, CY; Wang, Q, 2013)
"Multiple therapies are approved for the treatment of osteoporosis (OP), but many patients with osteoporosis may not initiate treatment upon osteoporosis diagnosis."( Gandhi, S; Modi, A; Sen, S; Siris, ES; Tang, J, 2014)
"Bisphosphonates are first-line treatment for osteoporosis."( Cadarette, SM; Juurlink, DN; Krahn, MD; Lévesque, LE; Mamdani, MM; Tadrous, M; Wong, L, 2014)
"In order to effectively treat osteoporosis, there has been an extended research on the biological activities of traditional medicines since synthetic medicines possess several side effects that reduce their efficacy."( Mohamed, N; Rufus, P; Shuid, AN, 2013)
"Despite substantial improvements in the treatment of osteoporosis over the last few decades, osteoporotic fractures are still a major clinical challenge in the elderly population due to impaired healing."( Guelcher, SA; Sterling, JA, 2014)
"Zoledronic acid is used in the treatment of osteoporosis."( Arkfeld, DG; Ibrahim, M; Metyas, S; Solyman, J; Yeter, KC, 2014)
"Antiresorptive agents, used in the treatment of osteoporosis, inhibit either osteoclast formation or function."( Ng, KW; Sims, NA, 2014)
"In order to improve the treatment of osteoporosis, available agents with roles of regulating the balance is highly desirable."( Hao, YQ; Lu, ZM; Yang, F; Yuan, PW, 2014)
"Two new approaches for the treatment of osteoporosis are summarized, each having arisen out of important new discoveries in bone biology."( Martin, TJ; Ng, KW, 2014)
"Individual agents used to treat human osteoporosis reduce fracture risk by ∼ 50-60%."( Amugongo, SK; Dai, W; Dave, NK; Jia, J; Jiang, L; Lane, NE; Lay, YA; Li, CS; Olivera, D; Panganiban, B; Ritchie, RO; Walsh, D; Yao, W, 2014)
"And it can have synergy effects on the treatment of osteoporosis if it is used combining with estrogen."( Bai, G; Di, J; Jiang, L; Lin, Z; Sun, Z, 2014)
"Different treatments for osteoporosis are available."( Gambacciani, M; Levancini, M, 2014)
"Bisphosphonates have been used to treat secondary osteoporosis in children, but limited experience and potential long-term toxicity warrant caution in routine use."( Cimaz, R; Corbin, KJ; Stagi, S; Stefano, S; von Scheven, E, 2014)
"The present treatments for osteoporosis relies on systemic medications intended to increase the bone mineral density (BMD)."( Gong, K; Liu, D; Pan, XM; Quan, Y; Wang, CR; Wu, ZX; Xie, QY; Zhang, B; Zhang, Y, 2016)
"Real-world persistence to treatment of osteoporosis is well-understood, but little is known of the posttreatment residual effect on fractures."( Garellick, G; Landfeldt, E; Ström, O, 2015)
"Despite the lack of consensus on the treatment of osteoporosis in NF1, risedronate may hold a promise as a potential therapy for osteoporosis complicating NF1."( Benlidayi, IC; Kozanoglu, E; Ortac, EA, 2015)
"We term this strategy as the "local treatment of osteoporosis"."( Li, G; Tang, H; Wang, J; Zhao, J, 2014)
"Drugs now approved for treatment of osteoporosis in men include the anti-resorptive bisphosphonates alendronate, residronate and zoledronic acid, the anti-resorptive drug denosumab, the bone-forming agent teriparatide, and (not in the US) strontium ranelate with mild opposite effects on resorption and formation."( Goemaere, S; Kaufman, JM; Lapauw, B, 2014)
"Recently, simvastatin has been used to treat osteoporosis more frequently; however, its clinical effect and treatment mechanism are still unknown."( Dai, L; Hu, M; Shen, Z; Wang, Y; Wu, H; Xu, M; Xue, L; Yuan, D; Zhao, H, 2016)
"The target to treat osteoporosis is prevention for future fractures."( Gorai, I, 2015)
"Bisphosphonates are widely used for the treatment of osteoporosis and other bone-degrading disorders; however, bisphosphonate therapy is an important risk factor for osteonecrosis of the jaws."( Kaneko, K; Takahashi, H, 2014)
"Eldecalcitol can be used for the treatment of osteoporosis without Ca supplementation to reduce the incidence of hypercalcemia and hypercalciuria, and enough hydration is recommended in order to avoid hypercalcemia, urolithiasis and deterioration of renal function."( Kondo, S; Matsumoto, T; Ono, Y; Saito, H; Takano, T, 2015)
"Denosumab is a biologic agent used to treat osteoporosis."( Chen, L; Curtis, JR; Delzell, E; Saag, KG; Xie, F; Yun, H, 2015)
"Many drugs for the treatment of osteoporosis have also been associated with increased risks of serious adverse events."( Aspenberg, P; Järvinen, TL; Michaëlsson, K; Sievänen, H, 2015)
"Bisphosphonates (BP) are used in the treatment of severe osteoporosis and metastasis of malignant diseases."( Koy, J; Koy, S; Lauer, G; Ney, M; Sabatowski, R; Schubert, M, 2015)
"Given the need for easily managed treatment of osteoporosis in HIV-infected patients, we evaluated the efficacy and tolerability of two doses of zoledronate, by comparing three groups of patients: those with annual administration, those with biennial administration (one dose in 2 years) and a control group with no administration of zoledronate."( Bonjoch, A; Clotet, B; del Río, L; di Gregorio, S; Echeverría, P; Estany, C; Herrero, C; Negredo, E; Ornelas, A; Pérez-Álvarez, N; Puig, J, 2015)
"Currently, there are several treatments for osteoporosis however; they all display some sort of limitation and/or side effects making the need for new treatments imperative."( Ghayor, C; Gjoksi, B; Ruangsawasdi, N; Siegenthaler, B; Weber, FE; Zenobi-Wong, M, 2015)
"The preferred treatment for osteoporosis in men is debated, and pairwise meta-analysis cannot obtain hierarchies of these treatments."( Chen, LX; Feng, SQ; Li, YL; Ning, GZ; Zhang, D; Zhang, TS; Zhou, ZR, 2015)
"Bisphosphonates are effective for the treatment of osteoporosis despite recent reports of safety concerns such as atypical femur fracture."( Bhattacharyya, T; Jha, S; Laucis, N; Wang, Z, 2015)
"Current treatments for osteoporosis involve the administration of high doses of bisphosphonates (BPs) over a number of years."( Hilborn, J; Kootala, S; Leeuwenburgh, S; Ossipov, D; van den Beucken, JJ, 2015)
"Bisphosphonates are widely used to treat osteoporosis, but have been associated with atypical femoral fractures (AFFs) in the long term, which raises a critical health problem for the aging population."( Acevedo, C; Allen, MR; Bale, H; Burr, DB; Busse, B; Gludovatz, B; Ritchie, RO; Schaible, E; Tang, SY; Wang, M; Wat, A; Zimmermann, EA, 2015)
"The use of SIM-loaded TC-PLGA NPs in treating osteoporosis was tested through animal pharmacodynamics analyses performed in ovariectomized rats, and the results suggested that the SIM-loaded TC-PLGA NPs can improve the curative effects of SIM on the recovery of bone mineral density compared to either SIM-loaded PLGA NPs or SIM alone."( Chai, G; Hu, FQ; Liu, J; Tao, S; Wang, H; Wang, J; Yuan, H, 2015)
"Active vitamin D3 is used for the treatment for osteoporosis in Japan."( Marumo, K; Saito, M, 2015)
"The prevention and treatment of osteoporosis is an increasingly important topic in the solid organ transplant (SOT) population."( Early, C; Stuckey, L; Tischer, S, 2016)
"This drug is used for treating osteoporosis, a major bone disease affecting hundreds of millions of people worldwide, especially postmenopausal women."( Farina, M; Querido, W; Rossi, AL, 2016)
"Bisphosphonates have been used to treat osteoporosis and have shown great success in conserving bone mass and reducing fracture incidence."( Curtin, CM; Duffy, GP; Lee, TC; McCoy, RJ; Mulcahy, LE; O'Brien, FJ; Taylor, D, 2015)
"However, the effects of treatment for osteoporosis on body composition are not well known."( Inoue, S; Kuroda, T; Shiraki, M; Tanaka, S; Uenishi, K; Urano, T, 2017)
"Although the patients with treated osteoporosis also showed lower BMD values, these were not statistically significant compared to group 3."( Čellár, R; Lacko, M; Schreierová, D; Vaško, G, 2015)
"Denosumab is currently used to treat osteoporosis and in prevention of skeletal related events in patients suffering from bone metastases due to solid tumors."( Kiesel, L; Kohl, A, 2016)
"Diagnosis and treatment of osteoporosis are extremely important."( O'Connor, KM, 2016)
"With life standard improved, the treatment of osteoporosis attracted more attention."( Bi, Y; Li, Y; Pu, W; Yan, Z; Yuan, X; Zhou, K, 2016)
"Current treatments of osteoporosis encompass changing lifestyles, taking orthopedic drugs, and invasive surgeries."( Jung, J; Stout, DA; Wei, D; Yang, H; Yang, L, 2016)
"In order to establish standards for the treatment of osteoporosis in AN, studies on pharmacological treatment are conducted."( Bartoszewicz, Z; Jagielska, GW; Przedlacki, J; Racicka, E, 2016)
"New drugs that appear promising in the treatment of osteoporosis include the cathepsin K inhibitor, monoclonal antibodies against sclerostin and parathyroid hormone-related protein analog."( Chan, CK; Cooper, C; Dennison, E; Mason, A, 2016)
"Denosumab is a relatively safe treatment of osteoporosis."( Chen, J; Smerdely, P, 2017)
"In most patients, treatment of osteoporosis is a long-term challenge."( Abrahamsen, B; Eiken, PA, 2017)
"Many of the therapeutic agents used to treat osteoporosis are known to be affected by the renal function."( Nitta, K; Tsuchiya, K; Yajima, A, 2017)
"Although the pharmacological treatment of osteoporosis has been extensively developed, alternative treatments are still needed."( Chen, S; Fan, S; Jie, Z; Qin, A; Sun, X; Tang, P; Wang, J; Xie, Z; Yu, H, 2018)
"To study the adequacy of evaluation and treatment of osteoporosis after fragility fractures of the hip."( Al Habsi, KSK; Al Harthy, HHS; Al Ruzaiqi, HAH; Venugopal Menon, K, 2018)
"Teriparatide, a hallmark treatment for osteoporosis, has been shown to increase BMD and bone turnover."( Beckett, T; Burkard, D; Kourtjian, E; Messingschlager, C; Padley, M; Sipahi, R; Stubbart, J, 2018)
"We reviewed the files of 53 patients treated for severe osteoporosis with teriparatide for 6 to 24 months between May 2008 and January 2016."( Bégin, MJ; Coupal, L; Ethier, J; Räkel, A; Ste-Marie, LG, 2018)
"Bisphosphonates are the primary treatment for osteoporosis."( Das, N; Gupta, T; Imran, S, 2019)
"Intravenous alendronate is an effective treatment for osteoporosis in SMID patients."( Aihara, M; Ishii, S; Kaga, Y; Kamiya, Y; Kanemura, H; Kuroda, I; Nakamura, K; Sugita, K, 2017)
"Interestingly, other treatments for osteoporosis have been developed, such as antibodies against the osteocyte-secreted protein, sclerostin."( Aghaloo, TL; Bezouglaia, O; Boyce, RW; Dry, SM; Dwyer, D; Gkouveris, I; Hadaya, D; Pirih, FQ; Soundia, A; Stolina, M; Tetradis, S, 2019)
"Commonly used drugs for the treatment of osteoporosis have severe side effects."( Han, W; Jia, Y; Jiang, J; Lu, X; Qian, Y; Yang, W; Zhang, T; Zhao, K, 2019)
"Current treatments for osteoporosis have many limitations, including the non-obvious therapeutic effect and long-term safety issues."( Bian, T; Huang, J; Li, C; Liu, Z; Lyu, J; Pi, F; Sun, X; Wei, J; Zhong, Z, 2019)
"Pharmacologic prevention and treatment for osteoporosis are recommended for all patients receiving glucocorticoids."( Adachi, JD; Hu, K, 2019)
"This behavior recommends that treatment of osteoporosis via calcitonin does not provide the required upshots."( Asif, A; Javed, S; Nutini, A; Sohail, A, 2020)
"Strategies for the treatment of osteoporosis involve inhibition of bone resorption by osteoclasts and an increase of bone formation by osteoblasts."( Choi, Y; Kim, JK; Kim, P; Kim, WJ; Lee, G; Lee, JS; Nam, YJ; Seo, JH; Song, MJ; Yang, J; Yi, SS, 2019)
"Men with self-rated poor health, those treated for osteoporosis; anxiety, depression or high blood cholesterol, and those who lived in major cities or were aged 55–74 years had greater odds of TRT initiation."( Bateson, D; Cheng, Y; Concepcion, K; Estoesta, J; Lowy, M; McGeechan, K; Stewart, M; Sweeney, S, 2018)
"The basic treatment for osteoporosis remained unchanged in both groups(600 mg of calcium carbonate D3 and 0."( Huang, K; Wan, JM; Zhang, JF; Zhang, PL; Zhu, SY, 2019)
"Combination and sequential treatments using osteoporosis medications with different mechanisms of action have also been tested with promising results."( Cheng, C; Shoback, DM; Wentworth, K, 2020)
"Individuals being treated for osteoporosis should be reevaluated for fracture risk routinely, including via patient education about osteoporosis and fractures and monitoring for adverse treatment effects."( Adib, G; Adler, RA; Åkesson, KE; Alexander, IM; Amenta, KC; Blank, RD; Brox, WT; Carmody, EE; Chapman-Novakofski, K; Clarke, BL; Cody, KM; Conley, RB; Cooper, C; Crandall, CJ; Dirschl, DR; Eagen, TJ; Elderkin, AL; Fujita, M; Greenspan, SL; Halbout, P; Hochberg, MC; Javaid, M; Jeray, KJ; Kearns, AE; Khosla, S; Kiel, DP; King, T; Koinis, TF; Koontz, JS; Kužma, M; Lindsey, C; Lorentzon, M; Lyritis, GP; Michaud, LB; Miciano, A; Morin, SN; Mujahid, N; Napoli, N; Olenginski, TP; Puzas, JE; Rizou, S; Rosen, CJ; Saag, K; Thompson, E; Tosi, LL; Tracer, H, 2020)
"Excessive treatment of osteoporosis weakens immunity and self-repair."( Jing, W; Liu, Z; Wu, J; Xiong, Z, 2020)
"In this review the problem of how to treat osteoporosis in patient with diabetes is also discussed."( Jackuliak, P; Kužma, M; Payer, J, 2019)
"Several pharmacological treatment of osteoporosis has been developed; however, new treatments are still necessary."( Cheng, HM; Li, HJ; Li, P; Thu, PM; Xu, X; Zheng, ZG; Zhou, YP; Zhu, ST, 2020)
"Bisphosphonates are widely used in the treatment of osteoporosis in postmenopausal women and older men."( Compston, J, 2020)
"There is no gold standard of treatment for osteoporosis."( Chen, K; He, W; Li, B; Li, Z; Wu, Q; Xia, J; Xu, S; Yang, Y; You, X; Yu, T; Zhao, Y; Zhou, H; Zhu, H, 2020)
"Steps to prevent or treat osteoporosis should be considered in all patients who take the equivalent of prednisone at a dose of 2."( Hayat, S; Magrey, MN, 2020)
"For this, apart from the treatment of osteoporosis, effective prevention of both the development of the disease and related fractures is extremely important."( Brzezińska, O; Makowska, J; Walczak, K; Łukasik, Z, 2020)
"Alendronate was later reintroduced as treatment for osteoporosis and the patient once again presented with severe hypophosphataemia in subsequent routine blood tests."( Bagger, LW; Hansen, PKD; Nielsen, BR; Schwarz, P, 2020)
"Gumi Bao decoction is effective for the treatment of osteoporosis, but the theoretical and scientific basis is unknown."( Cheng, J; Feng, H; Gong, Z; Liang, G; Liu, H; Shen, X; Su, F; Yang, L, 2020)
"Many drugs have been utilized to treat osteoporosis but the most effective one is the bisphosphonates (BPs) family."( Oryan, A; Sahvieh, S, 2021)
"Since currently available treatments for osteoporosis, such as administration of female hormones or hormone receptor modulators, show serious side effects, SPC has potential as a new agent for osteoporosis treatment."( Bae, YS; Cho, KM; Choi, CY; Kim, H; Kim, HH; Kim, KK; Kim, MK; Lee, HY; Lee, M; Park, JS, 2021)
"Current methods to treat osteoporosis include medical and surgical options such as bone implants."( Chiu, YC; Huang, TH; Kao, CT; Lee, AK; Lin, YH; Liu, YC; Shie, MY, 2021)
"Drugs for treating osteoporosis generally inhibit osteoclast (OC) activity, but are rarely aimed at encouraging new bone growth and often cause severe systemic side effects."( Hachim, D; Jones, JR; Li, S; McFarlane, T; Naruphontjirakul, P; Pinna, A; Porter, AE; Stevens, MM; Torki Baghbaderani, M; Vigil Hernández, V, 2021)
"deserticola for the treatment of osteoporosis and the potential mechanisms."( Jiang, Y; Tu, P; Wang, F; Zeng, K, 2021)
"Berberine has been reported to treat osteoporosis due to its beneficial actions on bone formation."( Bi, J; Chen, QC; Pu, YL; Zhang, Y, 2021)
"Group 1 included 83 patients treated for osteoporosis alone, and group 2 included 76 patients treated for both osteoporosis and symptomatic LSS."( Baek, IH; Ha, JY; Kim, KW; Lee, JS; Park, HY; Park, SB, 2021)
"Although the pharmacological treatment of osteoporosis has been extensively developed, a safer and more effective treatment is still needed."( An, Q; Fan, S; Jiang, C; Jie, Z; Ma, Q; Shen, Y; Wang, S; Xie, Z; Yuan, P; Zheng, B, 2021)
"Pharmaceutical treatment for osteoporosis involves bisphosphonates, calcium and vitamin D3, denosumab, teriparatide, raloxifene, and strontium ranelate."( Kosiorowska, J; Szymańska-Chabowska, A; Tański, W, 2021)
"Current treatments for osteoporosis are very frequently inadequate."( Berry, TM; Moustafa, AA, 2021)
"Bisphosphonate is used widely in the treatment of adult osteoporosis."( Hurley, T; McDonald, D; McDonnell, C; Molloy, E; Stewart, P; Zareen, Z, 2021)
"To conclude, Epimedin B is effective in treating osteoporosis in mice via regulating PI3K-Akt, MAPK and PPAR signalling pathway."( Bi, Y; Diao, X; Song, L; Wang, L; Zhou, K; Zhou, Y, 2021)
"Most agents for treating osteoporosis focus primarily on anti-resorption by inhibiting osteoclast activity."( Dai, M; Lai, Q; Li, X; Liu, X; Liu, Y; Mo, F; Xu, H; Xu, Q; Zhan, P; Zhang, B, 2021)
"Zoledronate is widely used for the treatment of osteoporosis."( Eastell, R; Khwaja, A; Peel, N; Salam, S; Schini, M; Thomas, E; Toronjo-Urquiza, L; Walsh, JS, 2022)
"Bisphosphonates are first-line treatment of osteoporosis, and we aimed to investigate whether the risk of developing type 2 diabetes was associated with prior use of alendronate."( Al-Mashhadi, Z; Starup-Linde, J; Vestergaard, P; Viggers, R, 2021)
"However, the treatment of osteoporosis is challenging."( Gan, L; Li, A; Li, L; Zhu, L; Zuo, L, 2022)
"Denosumab is a newly approved treatment for osteoporosis in China."( Fan, T; Li, W; Ning, Z; Wang, J; Wang, M; Wen, A; Yang, Z; Yao, M; Zhang, W, 2022)
"Considering the massive treatment gap for osteoporosis, and the related fracture risk, clinicians should continue treatment, even during a pandemic."( Behanova, M; Haschka, J; Kocijan, R; Reichardt, B; Resch, H; Stockinger, T; Zwerina, J, 2022)
"The drugs most commonly used in the treatment of osteoporosis are bisphosphonates."( Jakubowski, M; Ratajczak, M; Sandomierski, M; Voelkel, A, 2022)
"Zoledronic acid (ZA) is used for the treatment of osteoporosis (OP)."( Fixen, CW; Fixen, DR, 2022)
"Met may also treat diabetic osteoporosis through Wnt/β-catenin activation."( Huang, X; Li, S; Lu, W; Xiong, L, 2022)
"Osthole is an effective treatment for osteoporosis."( Lu, JH; Wang, WY; Wu, B; Yang, XQ; Zhu, XF, 2022)
"Continued treatment with osteoporosis medications was associated with reductions of fracture rates in a real-world setting."( Bartsch, R; Borchert, J; Hadji, P; Kossack, N; O'Kelly, J; Pignot, M, 2022)
"Continued treatment with osteoporosis medications was associated with reductions of fracture rates in a real-world setting."( Bartsch, R; Borchert, J; Hadji, P; Kossack, N; O'Kelly, J; Pignot, M, 2022)
"During 12 months of abaloparatide treatment, men with osteoporosis exhibited rapid and significant improvements in BMD with a safety profile consistent with previous studies."( Adachi, J; Binkley, N; Cardona, J; Chen, Y; Czerwinski, E; Kendler, D; Knychas, D; Lewiecki, EM; Li, YH; Mitlak, B; Orwoll, E; Pearman, L; Plebanski, R; Recknor, C; Saag, KG; Vokes, T, 2022)
"Antiresorptive therapy, first-line treatment for osteoporosis, is relatively contraindicated in HPP."( Ashkar, C; Ebeling, PR; Ng, E; Nguyen, H; Schneider, HG; Seeman, E; Sztal-Mazer, S, 2023)
"Antiresorptive therapy, first-line treatment for osteoporosis, is relatively contraindicated in HPP."( Ashkar, C; Ebeling, PR; Ng, E; Nguyen, H; Schneider, HG; Seeman, E; Sztal-Mazer, S, 2023)
"Antiresorptive therapy, first-line treatment for osteoporosis, is relatively contraindicated in HPP."( Ashkar, C; Ebeling, PR; Ng, E; Nguyen, H; Schneider, HG; Seeman, E; Sztal-Mazer, S, 2023)
"It is widely employed in the treatment of osteoporosis."( Ding, YF; Li, F; Liu, W; Liu, YY; Sui, HJ; Zhang, ZQ, 2023)
"It is widely employed in the treatment of osteoporosis."( Ding, YF; Li, F; Liu, W; Liu, YY; Sui, HJ; Zhang, ZQ, 2023)
"However, treatment of osteoporosis is far from satisfactory due to poor adherence to existing medications and adverse reactions, there is an urgent to develop novel therapies for osteoporosis."( Guo, J; Guo, Z; He, J; Ren, R; Shao, J; Sun, K; Wang, X, 2023)
"The number and proportion of patients treated with any osteoporosis medication were evaluated."( Diffenderfer, BW; Pearman, L; Pyrih, N; Wang, Y; Williams, SA, 2023)
"Bisphosphonates are prescribed to treat secondary osteoporosis in patients with rheumatoid arthritis (RA)."( Amano, K; Iida, S; Kogo, M; Sugauchi, A; Yamada, C, 2023)
"While overall diagnosis and treatment for osteoporosis have improved, osteoporosis in men remains underdiagnosed and undertreated."( Cheong, YR; Chuah, SL; Jobli, AT; Lee, KH; Lee, WWH; Samsudin, A; Singh, BSM; Teh, CL; Tiong, IK; Tiong, JK; Wan, SA, 2023)
"These medications are effective in treating osteoporosis but have side effects."( Gao, Z; Li, D; Li, Q; Liu, H; Liu, X, 2023)
"Zoledronic acid is used to treat osteoporosis, hypercalcemia, Paget's disease, and solid malignancies, including multiple myeloma, breast cancer, and prostate cancer."( Karpuz, S, 2023)
"Zoledronate (ZOL) is widely used to treat osteoporosis clinically."( Bi, W; Dong, W; Jia, S; Liang, Y; Qi, M; Song, Z; Wen, G; Xie, S; Zhang, Y, 2023)
"Developing novel drugs for treating osteoporosis is a popular research direction."( Gu, R; Li, W; Liu, H; Shao, Y; Xie, Z; Zeng, L; Zhou, Y; Zhu, Y, 2023)
"Drugs are normally prescribed to treat osteoporosis, especially after surgical treatment of osteoporotic fractures."( Bai, J; Chu, PK; Gao, A; Ge, G; Geng, D; Liu, X; Wang, G; Wang, H; Wang, Q; Wang, W; Wu, Z; Yu, L, 2023)
"BSHX treatment in osteoporosis model rats promoted tightening of the morphological structure of the trabecular bone and increased the bone mineral density (BMD)."( Chen, Y; Shi, H; Wang, Y; Wei, R; Wei, Z; Wen, X, 2023)

Research

Studies (16,233)

TimeframeStudies, This Condition (%)All Conditions %
pre-19903691 (22.74)23.3326
1990's1975 (12.17)12.5806
2000's4421 (27.23)18.1394
2010's4451 (27.42)28.8240
2020's1695 (10.44)9.53
DrugIndicatedRelationship StrengthStudiesTrials
dinitrochlorobenzene0low10
protocatechuic acid0low10
3-hydroxyanthranilic acid0low10
gamma-aminobutyric acid0low40
4-hydroxyphenylacetic acid0low10
4-hydroxybenzoic acid0low10
acetic acid0low20
acetaldehyde0low10
adenine0medium214
allantoin0low10
ammonium hydroxide0medium62
anthranilic acid0low10
beta-alanine0low10
benzaldehyde0low10
betaine0low20
1-butanol0low20
butyric acid0low20
carbamates0low20
carbamic acid0low10
formic acid0medium21
carnitine0medium101
methane0medium102
choline0low20
citric acid, anhydrous0medium193
chlorine0medium101
hydrochloric acid0low30
coumarin0medium51
salicylic acid0low30
phloroglucinol0low10
gallic acid0low80
hydrogen sulfide0low60
3-hydroxybutyric acid0low10
bupropion0low20
guaiacol0low10
2-aminoadipic acid0low10
methylmalonic acid0low40
n(g),n(g')-dimethyl-l-arginine0low10
aminocaproic acid0low20
creatine0medium193
cytosine0medium41
lactic acid0medium261
1,4-dihydroxy-2-naphthoic acid0low10
dimethylglycine0low10
ethanolamine0low10
formaldehyde0low20
glutaric acid0low10
glycine0low100
glycerol0medium52
hydrogen carbonate0medium242
dalteparin0medium93
histamine0medium132
hydrogen0medium72
iodine0low170
dihydroxyphenylalanine0low40
kynurenine0low90
thioctic acid0low40
pyruvaldehyde0low10
methanol0low80
phytic acid0low30
inositol0low80
melatonin0medium501
n-acetylserotonin0low10
nickel0low50
niacinamide0low60
niacin0low60
nitrates0medium102
nitrites0medium62
nitrous oxide0low10
orotic acid0low10
oxalic acid0low20
triphosphoric acid0low10
palmitic acid0low20
phenol0low10
phosphorylcholine0low10
phosphorylethanolamine0low10
phthalic acid0low20
picolinic acid0low10
pqq cofactor0low30
propylene glycol0medium22
1-propanol0low10
propionic acid0low10
pyrazinamide0low10
pyrazole0low20
pyridine0low10
pyridoxal phosphate0low20
sarcosine0low10
spermidine0low30
spermine0low30
sulfur dioxide0medium32
taurine0medium71
thiamine0low80
thymine0medium11
toluene0low10
trimethyloxamine0low30
trimethylamine0low10
uracil0low20
uric acid0low490
urea0medium143
8-hydroxy-2-(di-n-propylamino)tetralin0low10
menthol0low10
1-anilino-8-naphthalenesulfonate0low50
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine0low10
3,4-methylenedioxyamphetamine0low10
aminopropionitrile0low10
beta-phosphonopropionic acid0low20
phenytoin0low100
hydroxyindoleacetic acid0low10
acebutolol0low10
acetaminophen0medium72
acetazolamide0low60
6-acetylaminocaproic acid0low20
albuterol0medium33
alosetron0low10
alprazolam0low10
am 2510low10
aminoglutethimide0low10
theophylline0low50
amiodarone0low30
amlexanox0low10
amlodipine0low50
amobarbital0medium22
anastrozole0medium215
acetovanillone0low30
arecoline0low10
aspirin0medium301
azathioprine0medium303
2,2-bis(4-glycidyloxyphenyl)propane0low20
bamethan0low10
bendroflumethiazide0medium61
benzo(a)pyrene0low20
benzothiazide0medium32
benzyl benzoate0low10
berberine0low120
5-methoxypsoralen0low40
bicalutamide0medium142
bisbenzimidazole0low10
bisoprolol0low10
bromhexine0low10
bupivacaine0medium21
buspirone0low10
busulfan0low20
caffeine0low450
verapamil0low10
beta-glycerophosphoric acid0low20
camphor, (+-)-isomer0low10
carbamazepine0low80
carprofen0low10
carvedilol0low30
celecoxib0low60
cetirizine0low10
chetomin0low10
chlorambucil0low40
chlordiazepoxide0low10
chloroquine0low50
chlorothiazide0low10
chlorpromazine0low40
chlorpyrifos0low10
cimetidine0medium51
ciprofloxacin0low20
citalopram0low10
clobazam0medium11
clofibrate0low10
clofibric acid0low10
clomipramine0low10
clonidine0low20
cyclofenil0low10
dapsone0low20
deferiprone0low60
deferoxamine0low150
diazinon0low10
diclofenac0low40
pentetic acid0low20
diphenhydramine0medium11
dipyridamole0low10
disulfiram0low10
valproic acid0low90
donepezil0low20
doxepin0low10
ebselen0low10
embelin0low10
emodin0low60
enoxacin0low20
erythrosine0low120
ether0low10
etidronate0medium509107
etodolac0low10
famotidine0low10
felbamate0low10
fendiline0low10
fenofibrate0low20
fentanyl0low30
flufenamic acid0low20
flumazenil0low20
fluorouracil0medium51
fluoxetine0low30
flurbiprofen0low30
flutamide0medium93
furosemide0low80
gabapentin0low30
gemfibrozil0low10
gentamicin0low20
2,5-dihydroxybenzoic acid0low10
glimepiride0low10
glutaral0low10
glyphosate0low30
gossypol0low10
guaifenesin0low30
guanethidine0low30
guanidine0low10
1-(5-isoquinolinesulfonyl)-2-methylpiperazine0low10
fasudil0low20
haloperidol0low30
beta-thujaplicin0low10
hydralazine0low20
hydrochlorothiazide0medium224
hydroxychloroquine0low50
hydroxyurea0low70
ibuprofen0medium41
lidocaine0medium53
ifosfamide0low10
imipramine0low20
indirubin-3'-monoxime0low10
indomethacin0medium121
ipriflavone0medium469
avapro0low20
1-methyl-3-isobutylxanthine0low10
isoflurane0medium22
isoniazid0low10
2-propanol0low30
isoproterenol0low20
nsc 6647040low10
ketamine0medium43
ketotifen0low20
khellin0low10
kynurenic acid0low20
mimosine0low10
lamotrigine0low10
lansoprazole0low50
leflunomide0low10
lorazepam0low10
losartan0low10
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one0low20
memantine0medium22
vitamin k 30low10
meprobamate0low10
mesalamine0low40
metaproterenol0low10
metformin0medium292
methacrylic acid0low10
methadone0medium52
methocarbamol0low10
methoxsalen0low40
methyclothiazide0low20
methyl salicylate0medium22
methylphenidate0low10
metoprolol0low10
metronidazole0low20
metyrapone0low40
midazolam0medium21
mitoxantrone0low10
modafinil0low10
apnea0low10
activins0low70
nevirapine0medium11
nifedipine0low40
niflumic acid0low30
nilutamide0medium21
nimesulide0medium21
ofloxacin0medium11
omeprazole0medium91
oxybutynin0low60
oxymetazoline0low10
oxyphenbutazone0low10
fenclonine0low20
pantoprazole0medium21
pd 980590low20
pentoxifylline0low30
perphenazine0low10
phenacetin0low20
phenobarbital0low90
phenolphthalein0low30
phenylbutazone0low140
phloretin0low10
pifithrin0low10
pioglitazone0medium102
piracetam0low20
pirenzepine0low10
potassium chloride0medium31
primidone0low20
probenecid0low20
probucol0low20
procainamide0low20
procaine0low50
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pyrophosphate0medium281
bucillamine0low10
prednisolone hemisuccinate0low20
leuprolide0medium3712
nsc 43470low40
sesquiterpenes0low130
mercaptopurine0low50
methylthiouracil0low10
sb 3667910low20
caffeic acid0low10
4-iodo-6-phenylpyrimidine0low10
cotinine0low30
curcumin0low280
secinh30low10
thiouracil0low10
methimazole0medium52
capsaicin0low10
enclomiphene0low80
metiamide0low10
chlorogenic acid0low50
thioguanine anhydrous0low10
Pregnenolone acetate0low10
thiourea0low70
D-fructopyranose0low60
thioacetamide0low20
ferric ferrocyanide0low10
digoxin0low30
tamoxifen0medium11410
nadp0low20
1,1-diphenyl-2-picrylhydrazyl0low10
t 00709070low10
Benzo[b]thiophen-2-yl(morpholino)methanone0low10
methyl-thiohydantoin-tryptophan0low10
artemotil0low10
estrone sulfate0low20
ranitidine0medium21
Geraniin0low10
maraviroc0low10
toremifene0medium91
u 01260low50
dieckol0low10
lithium0low70
cobaltous chloride0low10
nitrogen dioxide0medium52
dermatan sulfate0low10
hydroxylysine0low120
droloxifene0low40
gestodene0medium11
idoxifene0low20
tat 590low10
ospemifene0low50
methenolone0low80
freedom0medium21
dasatinib0low10
ha 11000low10
arginyl-glycyl-aspartyl-phenylalanine0low20
nitinol0low10
sanorg 340060low10
cytellin0low20
eugenyl-beta-d-glucopyranoside0low10
ginsenosides0low110
quinagolide0low10
sw0332910low10
sto 6090low20
crocin0low20
alizarin red s0low50
alpha-chymotrypsin0low10
alpinetin0low10
ferrostatin-10low10
17-ketosteroids0medium221
naphthoquinones0low30
am 6300low10
osteoprotegerin0medium43716
timosaponin b-ii0low20
ex 5270low10
abacavir, lamivudine drug combination0medium22
isoliensinine0low10
sphingosine0low100
quercetin0low270
ubiquinone q20medium11
bilirubin0medium222
dinoprostone0medium371
dinoprost0low50
coniferin0low10
biochanin a0low30
apigenin0low30
luteolin0low30
7,3'-dihydroxy-4'-methoxyisoflavone0low10
linoleic acid0low30
vitamin k semiquinone radical0medium1579
beta carotene0medium171
retinol palmitate0low30
daphnetin0low10
alprostadil0low20
rutin0low50
kaempferol0low50
leukotriene d40low10
zeaxanthin0low20
lipoxin a40low10
gamma-linolenic acid0low10
alpha-linolenic acid0medium41
harmine0low20
pulmicort0medium2210
oxymetholone0medium61
montelukast0low20
mivacurium0low10
kava0low10
previtamin d(3)0low10
paricalcitol0low20
cyclobenzaprine0low10
astaxanthine0medium31
capsanthin0low10
cryptoxanthins0low40
lutein0low30
isobavachalcone0low30
azadirachtin0low10
geranylgeraniol0low20
genistin0low30
esculetin0low10
pteryxin0low10
humulene0low50
harpagoside0low10
oleuropein0low20
garcinol0low10
yangonin0low10
amentoflavone0low10
baicalein0medium62
chrysin0low20
chrysosplenetin b0low10
diosmin0low20
fisetin0low50
galangin0low20
hispidulin0low20
hyperoside0low10
morin0low30
morusin0low10
myricetin0low50
myricitrin0low20
sciadopitysin0low10
coumestrol0low40
pterostilbene0low20
echinacoside0low20
caffeic acid phenethyl ester0low20
acteoside0low20
psoralidin0low20
tectoridin0low10
tectorigenin0low10
wedelolactone0low10
ellagic acid0low20
coenzyme q100low60
anandamide0low10
cerulenin0low10
cilnidipine0low10
26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin d30low10
geranylgeranylacetone0low20
8-epi-prostaglandin f2alpha0low10
tocotrienol, delta0low10
etretinate0medium91
isotretinoin0medium41
fondaparinux0low20
pitavastatin0medium41
15-keto-13,14-dihydroprostaglandin f2alpha0low10
8-isoprostaglandin e20low20
4-hydroxy-2-nonenal0low20
menaquinone 60medium12227
sphingosine 1-phosphate0low90
purmorphamine0low10
codeine0medium11
phenylephrine hydrochloride0low30
acitretin0low20
cloprednol0medium11
cyproterone0medium63
granisetron0low10
hydromorphone0medium21
levetiracetam0low20
naloxone0low10
oxycodone0medium21
sirolimus0medium212
6,7,4'-trihydroxyisoflavone0low10
menaquinone 70medium125
fenretinide0low10
gw 56380low10
morphine0medium71
as 6052400low10
bibo 34570low10
cloprostenol0low20
deamino arginine vasopressin0low20
fluprostenol0low10
fluticasone0medium104
herbimycin0low10
goserelin0medium2610
iloprost0low10
lacidipine0low20
lysophosphatidic acid0low10
lysophosphatidylcholines0low30
ciguatoxins0low10
10-hydroxy-2-decenoic acid0low10
casticin0low20
biliverdine0low10
bisdemethoxycurcumin0low10
syringin0low20
linarin0low30
glycitein0low10
quadrangularin a0low10
andrographolide0low30
kukoamine a0low10
icaritin0low70
icariin0low520
ligustilide0low20
methyl-p-coumarate0low10
sophoricoside0low10
caryophyllene0low10
malealdehyde0low20
7,8-dimethylalloxazine0low10
casein kinase ii0low40
ag-4900low10
palbociclib0low10
lead0medium452
tin0low10
6,7-dihydroxyflavone0low10
bay 11-70820low10
barium0low40
aluminum0medium311
strontium0medium1233
arsenic0medium92
indium0low20
dextromethorphan0low10
gallium0low110
lisinopril0low10
indinavir sulfate0low20
sulfur0low40
costunolide0low10
vitamin mk 80low10
urolithin b0low20
puerarin0low110
7-hydroxymethotrexate0low10
ajoene0low10
enalapril0low20
ecdysterone0low40
fumarates0low50
beryllium0low10
cysteine0low40
silicon0low200
phosphorus0medium61233
boron0low70
heroin0low20
imidapril0low10
bakuchiol0low30
zerumbone0low10
icarrin0low20
lespenefril0low10
strontium radioisotopes0medium201
baohuoside i0low20
avicularin0low10
alpinumisoflavone0low20
aliskiren0low20
triolein0low10
guanabenz0low10
ap 100low10
25-hydroxyvitamin d 20medium312
salubrinal0low60
epimedin b0low10
epimedin c0low20
cladrin0low20
cinidon-ethyl0low10
propineb0low10
barium titanate(iv)0low10
germanium0medium51
selenium0low210
tellurium0low20
radium0medium71
oxalates0low60
aluminum hydroxide, magnesium hydroxide, drug combination0low10
(3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid0low60
maxacalcitol0low20
dizocilpine maleate0low10
antimycin a0low30
pregnanediol0medium21
cholestanol0low20
dolichols0low20
calcium fumarate0low10
24,25-dihydroxyvitamin d 30medium162
citreoviridin0low10
bafilomycin a10low20
ro 13-62980low20
sphingosine phosphorylcholine0low10
plastochromanol 80low20
1,25-dihydroxyvitamin d3-26,23-lactone0low10
2,3,5,4'-tetrahydroxystilbene 2-o-glucopyranoside0low10
tussilagone0low10
pregna-4,17-diene-3,16-dione0low10
echinacin0low10
nuezhenide0low10
everolimus0low20
hydroxysafflor yellow a0low20
mesobiliverdin0low10
1-hydroxyprevitamin d30low10
axitinib0medium22
ibutamoren mesylate0low10
salvianolic acid B0low20
rilpivirine0medium11
trilobatin0low10
technetium tc 99m pyrophosphate0low10
indigo carmine0low10
3 beta-o-acetylursolic acid0low10
tanespimycin0low10
beta-escin0low230
glucoraphanin0low10
echinocystic acid0low10
gadolinium dtpa0medium51
ergoline0low10
tetrahydrogestrinone0low10
sq-233770low10
collagen i, alpha chain (98-110)0low10
etonogestrel0low20
ginsenoside rb20low10
ciclesonide0low20
vorozole0low10
dutasteride0low20
nps21430low50
jwh-1330low10
omtriptolide0low10
relacatib0low20
1,25-dihydroxyergocalciferol0low20
tei 96470low10
hypericum0low30
taxane0low10
chlorhexidine0low40
s 17430medium11
gs-73400low10
gw 76040low10
ono48190low30
amoxicillin-potassium clavulanate combination0low40
sappanone a0low10
valyl-prolyl-proline0low10
sb 2232450low10
andarine0low30
a-3174910low10
sincalide0low20
technetium tc 99m diphosphonate0medium91
trestolone0low20
lg 1210710low10
ursodoxicoltaurine0low10
ginsenoside m10low30
gambogic acid0low10
mk-04290low20
pentagastrin0low10
cabazitaxel0low10
mocetinostat0low10
alloin0low10
avanafil0low10
yf 4760low10
em 8000low10
rivaroxaban0low40
lipid a0low10
dapagliflozin0medium11
ginsenoside rb10low20
secoisolariciresinol diglucoside0low10
ginsenoside rg30low20
sorbitan monooleate0medium22
ammonium trichloro(dioxoethylene-o,o'-)tellurate0low10
tofacitinib0low30
tocotrienols0low170
arginyl-glycyl-aspartyl-valine0low10
gw07420low20
zeolites0medium41
pitolisant0medium22
medrogestone0medium11
aluminum oxide0low20
ne 107900low10
4-hydroxy-n-desmethyltamoxifen0low10
linagliptin0low10
bismuth tripotassium dicitrate0medium11
heptakis(2,6-o-dimethyl)beta-cyclodextrin0low10
apixaban0low20
6-(3-hydroxyphenyl)-2-naphthol0low10
nps r-4670low10
fluorapatite0low10
artenimol0low20
anomalin0low10
edoxaban0low10
saracatinib0low20
alpha-synuclein0low10
kukoamine b0low10
ligustroflavone0low10
eckstolonol0low10
kmup 10low10
glaucocalyxin a0low10
macrolactin a0low10
ribose0low10
lactulose0low10
ptc 1240low10
epoxomicin0low10
fg-45920low10
zk-2194770medium11
mk 28660low40
bxl6280low10
Dihydrotanshinone I0low10
dorsomorphin0low10
quisinostat0low10
carfilzomib0low10
lgd 22260low10
ono-53340medium42
sitagliptin phosphate0low10
gw95080low20
N-methyl-N-[2-[[[2-[(2-oxo-1,3-dihydroindol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]phenyl]methanesulfonamide0low30
pf-562,2710low10
losartan potassium0low50
imidazolone0low10
pituitrin0low60
lhrh, ala(6)-gly(10)-ethylamide-0medium21
ugonin k0low10
monascin0low10
phytosterols0low20
dihydrotachysterol0low120
ent-dextilidine0low10
ginsenoside rc0low10
acid phosphatase0medium1804
mefloquine0low20
methylprednisolone 17-hemisuccinate0low10
chikusetsu saponin iva0low10
boeravinone b0low10
alisol c 23-acetate0low10
bavachin0low10
periplocin0low10
lyoniside0low10
calcium pidolate0low10
jaw0medium562
ankaflavin0low10
lg1901780low10
kirenol0low10
nad0low10
trelagliptin0low10
cytochrome c-t0low20
calcitonin0medium8527
cosyntropin0low10
cholecystokinin0low20
(4-24)-ply(a)0low10
humanin0low10
gastrins0low70
glucagon0medium82
beta-endorphin0low10
neuropeptide y0low80
echistatin0low10
angiotensinogen0low10
tannins0low20
oligonucleotides0low30
liraglutide0low50
glucagon-like peptide 10low120
vivit peptide0low10
incretins0low60
c-peptide0low70
cellulose0medium52
perovskite0low10
endothelin-10low10
phosphatidylcholines0low40
(9R)-9-chloro-11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one0medium167
pamapimod0low20
prunetin 4'-O-glucoside0low10
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone0low10
carbetocin0low10
vendex0low430
WAY-3166060low10
sodium salicylate0low10
ubiquinone0medium81
tyrosyl-glutamyl-tyrosyl-glutamic acid0low10
calpain0low20
sapogenins0low10
4'-hydroxy-5,6,7,8,3'-pentamethoxyflavone0low10
2'-acetylacteoside0low10
dihydrobenzoxathiin0low10
silicate cement0low20
menotropins0low20
chitosan0medium212
technetium tc 99m sestamibi0low20
enzacamene0low10
raltegravir potassium0medium11
stearates0low10
holothurin a0low10
alendronate sodium0low10
sodium ethylxanthate0low120
mersalyl0low10
cortisol succinate, sodium salt0low20
srt17200low20
cx 49450low10
s-adenosylmethionine0medium21
gdc 04490low10
gdc-00680low10
bms 7776070low10
canagliflozin0low20
pci 327650low10
madecassoside0low10
arabinogalactan0low10
intrinsic factor0low20
zoanthenol0low10
navitoclax0low10
egg white0low10
corylifol a0low10
quetiapine fumarate0low20
cardiovascular agents0low150
trelstar0medium93
nafarelin0medium53
apelin-13 peptide0low20
lhrh, n-ac-(4-cl-phe)(1,2)-trp(3)-arg(6)-alanh2(10)-0low10
osteogenic growth peptide0low20
alloferon0low10
vel-02300low10
cym-55200low10
incb-0184240low20
mannans0low20
pexidartinib0low10
lgd 33030low20
(1-(4-(naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-yl)methanamine0low10
9r-(9alpha(z),10alpha) of 3'-angeloyloxy-4'-acetoxy-3',4'-dihydroseselin0low10
glycolipids0medium52
piperidines0medium373
madindoline a0low10
interleukin-80medium72
lp5334010low40
5-(4-amino-1-propan-2-yl-3-pyrazolo[3,4-d]pyrimidinyl)-1,3-benzoxazol-2-amine0medium22
int-7770low10
exenatide0low50
kavain0low10
ophiopogonin d0low10
fructose-1,6-diphosphate0low20
gyy 41370low10
bix 012940low10
methylcellulose0low20
isoquercitrin0low20
gsk1210151a0low10
vasoactive intestinal peptide0low10
natriuretic peptide, brain0low20
acy-12150low10
heme0medium22
chondroitin0low30
heparitin sulfate0low10
glutarylcarnitine0low10
ascorbic acid0medium833
tetracycline0low690
chlortetracycline0low30
oxytetracycline, anhydrous0low40
minocycline0low30
methacycline0low10
salicylates0medium71
piroxicam0low10
acenocoumarol0medium11
mobic0low10
warfarin0medium602
ascorbate-2-phosphate0low10
demeclocycline0low60
antimycin0low10
pogostone0low10
dolutegravir0medium11
fluticasone propionate, salmeterol xinafoate drug combination0medium11
epidermal growth factor0low40
calca protein, human0low20
clay0low20
rhodostomin0low10
holothurin0low10
transforming growth factor beta0low1360
phytoestrogens0low1130
okadaic acid0low10
gsk28795520low10
ponicidin0low10
kiss1 protein, human0medium11
curcumin glucuronide0low10
rome0low30
agar0low10
hirudin0low10
glutaminase0low10
cyclin d10low80
contraceptives, postcoital0low10
caseins0low90
nattokinase0low20
myrtecaine0low10
3-hydroxy-4-prenyl-5-methoxystilbene-2-carboxylic acid0low10
azd94960low10
1 alpha,24-dihydroxyvitamin d30low30
glucagon-like peptide 20medium71
angiotensin i0low20
hyaluronoglucosaminidase0low10
inokosterone0low10
harpagide0low10
ginkgolide b0low20
neferine0low10
oridonin0low20
morroniside0low40
sanggenone c0low10
peoniflorin0low20
vitamin b 120medium485
ferric ammonium citrate0low20
insulin glargine0low10
cyperenoic acid0low10
norgestrel0medium21
oxyntomodulin0low20
cyclosporine0medium468
epimedin a0low20
silybin0low30
peptide yy0low20
lactoferrin0low40
akebia saponin d0low20
protopanaxadiol0low10
catalpol0medium72
neohesperidin0low30
tomatine0low10
poncirin0low10
phenylbutazone, propyphenazone drug combination0low10
orabase0low10
technetium tc 99m medronate0medium553
apyrase0low10
thromboplastin0low20
muramidase0low20
liriodendrin, 1r-(1alpha,3abeta,4beta,6aalpha)-isomer0low10
chondroitin sulfates0medium111
exudates0medium413
angiogenin0low10
protopanaxatriol0low10
technetium tc 99m dimercaptosuccinic acid0medium11
entecavir0low20
levoleucovorin0low10
cyclic gmp0low40
deoxyguanosine0low20
guanosine monophosphate0low10
guanosine triphosphate0low10
guanine0medium51
sapropterin0low10
neopterin0low30
clozapine0low20
olanzapine0low20
zaprinast0low10
allopurinol0low40
tegaserod0low10
sildenafil citrate0low20
da 81590low10
vardenafil dihydrochloride0low20
xav9390low10
hesperadin0low10
trypan blue0low20
8-hydroxy-2'-deoxyguanosine0low30
amg5310low10
6-methyl-1,2,3,5-tetrahydroimidazo(2,1-b)quinazolin-2-one hydrochloride0low10
cytidylyl-3'-5'-guanosine0low10
carthamine0low10
glucosepane0low10
cholestyramine resin0medium31
eye0low60
fructooligosaccharide0medium21
acetylcellulose0medium22
abaloparatide0medium457
concanavalin a0low10
metallothionein0low20
phosphorus radioisotopes0low10
leptin0medium1294
pyrimidinones0medium32
phenanthrenes0low40

Protein Targets (4,289)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
PPM1D protein900090
cytochrome P450 family 3 subfamily A polypeptide 424600246
G18600186
cytochrome P450 2D615100151
Dickkopf-related protein 10011
Interferon beta25600256
HLA class I histocompatibility antigen, B alpha chain 18600186
Glycogen synthase kinase-3 beta0221840
Inositol hexakisphosphate kinase 118600186
cytochrome P450 2C9, partial18600186
Cytochrome P450 2C9 01084119
IDH110400104
chromobox protein homolog 120900209
geminin32400324
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE19400194
thioredoxin reductase17500175
ATAD5 protein, partial14100141
GLS protein13600136
TDP1 protein38900389
regulator of G-protein signaling 412000120
67.9K protein970097
Parkin430043
bromodomain adjacent to zinc finger domain 2B790079
euchromatic histone-lysine N-methyltransferase 230500305
nuclear factor erythroid 2-related factor 2 isoform 210000102
huntingtin isoform 2410041
ras-related protein Rab-9A520052
serine/threonine-protein kinase mTOR isoform 1540054
urokinase-type plasminogen activator precursor770077
plasminogen precursor770077
urokinase plasminogen activator surface receptor precursor770077
survival motor neuron protein isoform d13600136
D(1A) dopamine receptor282030
Ataxin-215400154
ATP-dependent phosphofructokinase13000130
Chain B, pheromone binding protein0011
Chain A, pheromone binding protein0011
Chain A, JmjC domain-containing histone demethylation protein 3A10100101
Chain A, RNA-directed RNA polymerase NS50404
acid sphingomyelinase210021
USP1 protein, partial18600186
vitamin D3 receptor isoform VDRA14100141
importin subunit beta-1 isoform 1510051
flap endonuclease 1950095
serine/threonine-protein kinase PLK1400040
snurportin-1510051
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1690069
GTP-binding nuclear protein Ran isoform 1290029
DNA polymerase eta isoform 1480048
DNA polymerase iota isoform a (long)13100131
DNA polymerase kappa isoform 111200112
fibroblast growth factor 22 isoform 1 precursor0004
Mitogen-activated protein kinase 1306713
Beta-lactamase0606
Transthyretin0111531
Fatty acid-binding protein, intestinal010212
Fatty acid-binding protein, adipocyte08311
Cyclin-A20909
Cannabinoid receptor 1016723
Cyclin-dependent kinase 20182038
Choline O-acetyltransferase0202
Mitogen-activated protein kinase 1206713
Guanine nucleotide-binding protein G470047
Fatty acid-binding protein 50527
Fatty acid-binding protein 50033
Mitogen-activated protein kinase 11061925
Mitogen-activated protein kinase 140292150
aldehyde dehydrogenase 1 family, member A123900239
glucocorticoid receptor [Homo sapiens]30900309
farnesoid X nuclear receptor19100191
estrogen nuclear receptor alpha46700467
Voltage-dependent calcium channel gamma-2 subunit16100161
Cellular tumor antigen p5326300263
Glutamate receptor 217166184
Choline O-acetyltransferase 0305
glucocerebrosidase570057
Alpha-mannosidase0202
alpha-galactosidase330033
Trehalase 0202
lysosomal alpha-glucosidase preproprotein460046
Trehalase0101
Maltase-glucoamylase, intestinal0606
Trehalase 0202
Lysosomal acid glucosylceramidase0415
Alpha-galactosidase A0101
Alpha-glucosidase MAL620202
Lactase-phlorizin hydrolase0202
Lysosomal alpha-glucosidase0808
Beta-glucosidase A0101
Sucrase-isomaltase, intestinal0505
Alpha-1B adrenergic receptor081586
Sucrase-isomaltase, intestinal0808
Alpha-1D adrenergic receptor040547
Beta-glucosidase0101
Protein-lysine 6-oxidase0606
Alpha-mannosidase 20202
Glycogen debranching enzyme0202
Glycogen debranching enzyme0101
Alpha-glucosidase MAL320303
Alpha-1A adrenergic receptor086692
Oligo-1,6-glucosidase IMA10202
Alpha-glucosidase MAL120808
Oxysterols receptor LXR-beta06411
Spike glycoprotein149718174
Alpha-amylase 0102
Trehalose synthase/amylase TreS0101
Lactase-phlorizin hydrolase 0202
Oxysterols receptor LXR-alpha04712
Neutral alpha-glucosidase AB0202
Ceramide glucosyltransferase0202
Lysosomal acid glucosylceramidase0101
Probable maltase-glucoamylase 20303
Beta-glucosidase 0101
Lysosomal alpha-glucosidase0505
Cytosolic beta-glucosidase0101
Non-lysosomal glucosylceramidase0202
Putative alpha-glucosidase0202
thyroid stimulating hormone receptor14300143
vitamin D (1,25- dihydroxyvitamin D3) receptor19500195
thyroid hormone receptor beta isoform a11200112
nuclear factor erythroid 2-related factor 2 isoform 130300303
Luciferase15500155
RAR-related orphan receptor gamma29800298
GLI family zinc finger 330600306
AR protein39500395
nuclear receptor subfamily 1, group I, member 323400234
progesterone receptor21900219
retinoic acid nuclear receptor alpha variant 130300303
retinoid X nuclear receptor alpha25500255
pregnane X nuclear receptor28200282
peroxisome proliferator-activated receptor delta20400204
peroxisome proliferator activated receptor gamma22500225
aryl hydrocarbon receptor14900149
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a23800238
activating transcription factor 612800128
v-jun sarcoma virus 17 oncogene homolog (avian)16000160
Histone H2A.x13000130
thyroid hormone receptor beta isoform 229800298
heat shock protein beta-112200122
Chain A, High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, Phosphodiesterase 9A0101
Chain A, Class I phosphodiesterase PDEB10101
Chain A, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
Chain A, cGMP-dependent 3',5'-cyclic phosphodiesterase0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase catalytic domain, Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha chimera0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase catalytic domain, Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha chimera0101
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A0101
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A0101
glp-1 receptor, partial930093
estrogen-related nuclear receptor alpha33500335
Phosphodiesterase 0606
mitogen-activated protein kinase 111200112
cytochrome P450 3A4 isoform 118700187
histone acetyltransferase KAT2A isoform 111000110
cGMP-dependent 3',5'-cyclic phosphodiesterase010010
Gamma-aminobutyric acid receptor subunit pi187245216
Monocarboxylate transporter 40202
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0505
cGMP-specific 3',5'-cyclic phosphodiesterase026128
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A0404
Renin09110
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0808
cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0506
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0506
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0507
Gamma-aminobutyric acid receptor subunit beta-1187245216
Gamma-aminobutyric acid receptor subunit delta187245216
Gamma-aminobutyric acid receptor subunit gamma-2187256218
Gamma-aminobutyric acid receptor subunit alpha-5187255217
Gamma-aminobutyric acid receptor subunit alpha-3187245216
Gamma-aminobutyric acid receptor subunit gamma-1187255217
Gamma-aminobutyric acid receptor subunit alpha-2187245216
Adenosine receptor A1132242
Gamma-aminobutyric acid receptor subunit alpha-4187245216
Gamma-aminobutyric acid receptor subunit gamma-3187245216
Adenosine receptor A30606
Adenosine receptor A2a022734
Adenosine receptor A2b0319
Adenosine receptor A2b09213
Gamma-aminobutyric acid receptor subunit alpha-6187245216
Adenosine receptor A1024638
Adenosine receptor A2a027440
Sodium-dependent serotonin transporter035238
Adenosine receptor A2a0303
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'0415
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0506
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A0809
Gamma-aminobutyric acid receptor subunit alpha-1187276220
Gamma-aminobutyric acid receptor subunit beta-3187255217
Gamma-aminobutyric acid receptor subunit beta-2187246217
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0808
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0809
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0505
cAMP-specific 3',5'-cyclic phosphodiesterase 4B015118
cAMP-specific 3',5'-cyclic phosphodiesterase 4D017119
cGMP-inhibited 3',5'-cyclic phosphodiesterase B011012
Voltage-dependent L-type calcium channel subunit alpha-1C031032
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0606
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C09010
cGMP-inhibited 3',5'-cyclic phosphodiesterase A012013
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0505
Phosphodiesterase 0101
GABA theta subunit187245216
Phosphodiesterase 0505
Gamma-aminobutyric acid receptor subunit epsilon187245216
cAMP-specific 3',5'-cyclic phosphodiesterase 7B0404
Dihydropteridine reductase0101
Amine oxidase [flavin-containing] A053156
Amine oxidase [flavin-containing] B046047
Amine oxidase [flavin-containing] B0506
Smad310300103
interleukin 8520052
hypoxia-inducible factor 1 alpha subunit11400114
ATPase family AAA domain-containing protein 511600116
acetylcholinesterase12400124
SMAD family member 212600126
SMAD family member 312600126
estrogen receptor 2 (ER beta)18800188
thyroid stimulating hormone receptor12700127
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a12700127
histone deacetylase 9 isoform 3430043
nuclear factor NF-kappa-B p105 subunit isoform 1200222
lamin isoform A-delta1024600246
pregnane X receptor510051
Microtubule-associated protein tau18000180
arylsulfatase A960096
nuclear receptor subfamily 1, group I, member 2590059
Glucocorticoid receptor161988
Sex hormone-binding globulin032932
Glycine receptor subunit alpha-1052052
Corticosteroid-binding globulin017018
Adenosine receptor A3053357
Replicase polyprotein 1ab0682593
Androgen receptor094196
Glycine receptor subunit beta052052
Glycine receptor subunit alpha-2052052
Glycine receptor subunit alpha-3052052
Mitogen-activated protein kinase 3 041722
Sodium-dependent dopamine transporter 069271
TAR DNA-binding protein 43881089
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-10101
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-10101
Chain A, HADH2 protein12900129
Chain B, HADH2 protein12900129
Chain A, 2-oxoglutarate Oxygenase13600136
Chain A, Cruzipain650065
Chain A, Methyltransferase Wbdd0101
15-lipoxygenase, partial850085
NFKB1 protein, partial510051
Thrombopoietin450045
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)820082
EWS/FLI fusion protein21700218
cytochrome P450 2D6 isoform 1900090
cellular tumor antigen p53 isoform a840084
cytochrome P450 2C19 precursor910091
cytochrome P450 2C9 precursor860086
M-phase phosphoprotein 8580058
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform07715
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha0101
Serine/threonine-protein kinase PLK4041721
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta0167
Polyunsaturated fatty acid lipoxygenase ALOX15B797086
Bromodomain-containing protein 40538
5-hydroxytryptamine receptor 4073477
Integrin beta-36211276
Cytochrome P450 1A2066376
Integrin alpha-IIb628171
Neuronal acetylcholine receptor subunit alpha-41713334
Serine/threonine-protein kinase pim-10151836
Neuronal acetylcholine receptor subunit beta-21713334
Casein kinase II subunit alpha'0231841
Proteinase-activated receptor 10214
Bromodomain-containing protein 20314
Phosphatidylinositol 3-kinase regulatory subunit alpha0203
5-hydroxytryptamine receptor 2A069273
5-hydroxytryptamine receptor 2C081384
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0101
Type-1 angiotensin II receptor0527
5-hydroxytryptamine receptor 2B084387
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform09717
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 0101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform06715
Serine/threonine-protein kinase mTOR010919
Serine/threonine-protein kinase mTOR0101
Histamine H2 receptor13353145
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 09717
Serine/threonine-protein kinase PLK10111324
Casein kinase II subunit beta023124
Casein kinase II subunit alpha026834
DNA-dependent protein kinase catalytic subunit0808
Mu-type opioid receptor024327
Serine-protein kinase ATM0303
Serine/threonine-protein kinase ATR0358
Bromodomain-containing protein 30314
Serine/threonine-protein kinase pim-30268
Phosphoinositide 3-kinase regulatory subunit 50101
Serine/threonine-protein kinase PLK305611
Serine/threonine-protein kinase PLK204610
Xanthine dehydrogenase/oxidase033033
Chain A, Beta-lactamase11100111
interferon gamma precursor00010
atrial natriuretic peptide receptor 2 precursor280028
DNA dC->dU-editing enzyme APOBEC-3G isoform 1205025
Tubulin alpha-1A chain0326
Tubulin beta chain0325
Cytochrome P450 1A1031335
Cytochrome P450 1B1037240
Tubulin beta-2B chain0518
Similar to alpha-tubulin isoform 1 0417
Similar to alpha-tubulin isoform 1 0406
DNA repair and recombination protein RadA0022
Cytochrome P450 2A6020324
Sulfotransferase 1A1 0004
Cytochrome P450 2A50405
Sulfotransferase 1E10001
Sulfotransferase 1A10215
Sulfotransferase 2A10001
Chain A, Ferritin light chain950095
caspase 7, apoptosis-related cysteine protease730073
caspase-3730073
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 111400114
potassium voltage-gated channel subfamily H member 2 isoform d11400114
Peroxisome proliferator-activated receptor gamma0132238
Nuclear receptor ROR-gamma713478
Glycogen synthase kinase-3 alpha0131730
Carbonic anhydrase 12048164
Carbonic anhydrase 10921118
Carbonic anhydrase 201024132
72 kDa type IV collagenase019019
Matrilysin0707
Polyunsaturated fatty acid 5-lipoxygenase038139
Aminopeptidase N0202
Prolyl 4-hydroxylase subunit alpha-10707
Tyrosine-protein phosphatase non-receptor type 1044351
Carbonic anhydrase 7046159
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT60606
Alpha-(1,3)-fucosyltransferase 70606
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 10606
Carbonic anhydrase 9051270
Carbonic anhydrase 14033148
peripheral myelin protein 2214300143
Alpha-crystallin B chain0011
3-hydroxy-3-methylglutaryl-coenzyme A reductase010111
Integrin alpha-V 08110
Glutamate receptor ionotropic, NMDA 1010414
Sterol regulatory element-binding protein 20101
Glutamate receptor ionotropic, NMDA 2A010414
Glutamate receptor ionotropic, NMDA 2B010516
Oxysterol-binding protein 20011
NPC1-like intracellular cholesterol transporter 10022
Chain A, ATP-DEPENDENT DNA HELICASE Q1530053
nonstructural protein 1600060
DNA polymerase beta570057
nuclear receptor ROR-gamma isoform 115100151
streptokinase A precursor001717
Glycogen phosphorylase, muscle form0909
Tyrosyl-DNA phosphodiesterase 10303
endonuclease IV430043
phosphopantetheinyl transferase14200142
Fumarate hydratase900090
thioredoxin glutathione reductase550055
polyprotein900090
Bloom syndrome protein isoform 110100101
NPC intracellular cholesterol transporter 1 precursor400040
peripheral myelin protein 22 isoform 1650065
FAD-linked sulfhydryl oxidase ALR0007
muscarinic acetylcholine receptor M1810081
Guanylate cyclase soluble subunit beta-20012
Guanylate cyclase soluble subunit alpha-20012
Alpha-synuclein3821160
Guanylate cyclase soluble subunit alpha-10023
Guanylate cyclase soluble subunit beta-10023
Histone acetyltransferase p3000505
Hypoxia-inducible factor 1-alpha0718
CREB-binding protein2417
Endothelial PAS domain-containing protein 10505
Protein polybromo-10022
Chain A, Phenazine biosynthesis protein phzF0011
Caspase 6, apoptosis-related cysteine peptidase0004
isocitrate dehydrogenase 1, partial130013
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0606
glucose-6-phosphate 1-dehydrogenase isoform b0606
replicative DNA helicase0002
recombinase A0022
Caspase-7220024
Caspase-90304
large T antigen017118
Protein skinhead-10101
Monocarboxylate transporter 20303
Solute carrier family 22 member 20012012
Solute carrier family 22 member 6012012
apical membrane antigen 1, AMA1490049
ATP-dependent translocase ABCB107112111
Calmodulin-109211
Androgen receptor1481883
Pyruvate kinase PKM011314
Polyunsaturated fatty acid lipoxygenase ALOX15011011
Polyunsaturated fatty acid lipoxygenase ALOX120909
Fatty acid synthase012012
Aurora kinase B0201636
Dipeptidyl peptidase 3010010
HSP40, subfamily A [Plasmodium falciparum 3D7]0004
Kynureninase0101
Chain A, Putative fructose-1,6-bisphosphate aldolase840084
pyruvate kinase PKM isoform a110011
Glycoprotein hormones alpha chain8008
Tubulin--tyrosine ligase0202
Regulatory protein E20011
Aldo-keto reductase family 1 member C3013013
Trace amine-associated receptor 10022
Trace amine-associated receptor 10022
5-hydroxytryptamine receptor 2C030335
5-hydroxytryptamine receptor 2A041547
5-hydroxytryptamine receptor 1A062675
Sodium-dependent noradrenaline transporter 09111102
Sodium-dependent dopamine transporter029332
5-hydroxytryptamine receptor 1B042346
5-hydroxytryptamine receptor 1D013317
5-hydroxytryptamine receptor 1F013317
5-hydroxytryptamine receptor 2B029433
5-hydroxytryptamine receptor 60628
Sodium-dependent serotonin transporter085893
5-hydroxytryptamine receptor 7 014216
5-hydroxytryptamine receptor 5A0628
5-hydroxytryptamine receptor 5B0628
5-hydroxytryptamine receptor 3A09211
5-hydroxytryptamine receptor 4 0628
5-hydroxytryptamine receptor 3B09211
Transient receptor potential cation channel subfamily A member 104610
Estrogen receptor1731999
Aromatase050060
Chain A, PROTOCATECHUATE 3,4-DIOXYGENASE0202
Chain M, PROTOCATECHUATE 3,4-DIOXYGENASE0202
Chain A, PROTOCATECHUATE 3,4-DIOXYGENASE0202
Chain M, PROTOCATECHUATE 3,4-DIOXYGENASE0202
Chain A, PROTOCATECHUATE 3,4-DIOXYGENASE0202
Chain M, PROTOCATECHUATE 3,4-DIOXYGENASE0202
Chain A, PROTOCATECHUATE 3,4-DIOXYGENASE0202
Chain M, PROTOCATECHUATE 3,4-DIOXYGENASE0202
Chain A, PROTOCATECHUATE 3,4-DIOXYGENASE0202
Chain M, PROTOCATECHUATE 3,4-DIOXYGENASE0202
Chain A, Protocatechuate 3,4-dioxygenase0202
Chain M, Protocatechuate 3,4-dioxygenase0202
Polyphenol oxidase 2036146
Carbonic anhydrase 3028138
Tyrosinase017017
D(1A) dopamine receptor046455
Carbonic anhydrase 4059172
Carbonic anhydrase 6036149
Carbonic anhydrase 5A, mitochondrial036253
Thiopurine S-methyltransferase0202
Succinate-semialdehyde dehydrogenase, mitochondrial0202
4-aminobutyrate aminotransferase, mitochondrial0405
Carbonic anhydrase0606
Carbonic anhydrase 15025032
Carbonic anhydrase 13024034
Toll-like receptor 2 0202
Carbonic anhydrase 5B, mitochondrial032148
Chain A, Penicillin Amidohydrolase0202
Chain B, Penicillin Amidohydrolase0202
Chain A, Penicillin Amidohydrolase0202
Chain B, Penicillin Amidohydrolase0202
Chain A, Penicillin Amidohydrolase0202
Chain B, Penicillin Amidohydrolase0202
Chain A, Penicillin Amidohydrolase0202
Chain B, Penicillin Amidohydrolase0202
Chain A, Penicillin Amidohydrolase0202
Chain B, Penicillin Amidohydrolase0202
Chain A, Penicillin Amidohydrolase0202
Chain B, Penicillin Amidohydrolase0202
Chain A, Penicillin Amidohydrolase0202
Chain B, Penicillin Amidohydrolase0202
Olfactory receptor class A-like protein 10011
Carbonic anhydrase 0606
Beta-carbonic anhydrase 1012012
Carbonic anhydrase 08015
Carbonic anhydrase09017
Calcium/calmodulin-dependent protein kinase type II subunit alpha04610
Hepatocyte growth factor receptor071725
Macrophage migration inhibitory factor013013
Aldo-keto reductase family 1 member B1085085
Rapamycin-insensitive companion of mTOR0101
Regulatory-associated protein of mTOR0303
Phosphatidylinositol 3-kinase catalytic subunit type 30011
Target of rapamycin complex 2 subunit MAPKAP10101
Target of rapamycin complex subunit LST80303
dual specificity tyrosine-phosphorylation-regulated kinase 1A0007
lethal factor (plasmid)900090
Cytochrome P450 3A401079129
Cytochrome P450 2D6073481
Potassium voltage-gated channel subfamily A member 20011
Potassium voltage-gated channel subfamily A member 30112
Potassium voltage-gated channel subfamily A member 60011
Potassium voltage-gated channel subfamily A member 30202
Potassium voltage-gated channel subfamily A member 50314
Cytochrome P450 2C19057264
Potassium voltage-gated channel subfamily C member 10011
Beta-secretase 1034035
Potassium voltage-gated channel subfamily A member 10224
17-beta-hydroxysteroid dehydrogenase type 10708
Cytochrome P450 2B6020125
17-beta-hydroxysteroid dehydrogenase type 20808
Estrogen receptor beta1431360
Geranylgeranyl pyrophosphate synthase010012
Farnesyl pyrophosphate synthase019019
polyunsaturated fatty acid lipoxygenase ALOX12280028
caspase-1 isoform alpha precursor230023
Aldo-keto reductase family 1 member B10707
Tyrosinase011011
Vitamin D3 receptor081126
BRCA1190019
mu-type opioid receptor isoform MOR-10033
5-hydroxytryptamine receptor 2A0033
5-hydroxytryptamine receptor 1A020930
D(2) dopamine receptor051868
Translocator protein09211
D020020
D(3) dopamine receptor022022
Alpha-2B adrenergic receptor027533
D(2) dopamine receptor010010
Alpha-2C adrenergic receptor027533
Alpha-2A adrenergic receptor027533
Alpha-1D adrenergic receptor050557
5-hydroxytryptamine receptor 1D0409
5-hydroxytryptamine receptor 1B0527
5-hydroxytryptamine receptor 7017118
Alpha-1A adrenergic receptor015623
Alpha-1B adrenergic receptor012519
5-hydroxytryptamine receptor 5A0303
5-hydroxytryptamine receptor 6053155
5-hydroxytryptamine receptor 7019019
D(2) dopamine receptor034641
D0303
5-hydroxytryptamine receptor 2A0202
Sigma non-opioid intracellular receptor 1164368
Lysosomal alpha-glucosidase0202
Transporter017119
Chain A, Avidin0022
Chain A, Avidin0022
Chain B, Avidin0022
Voltage-dependent T-type calcium channel subunit alpha-1G0213
Voltage-dependent T-type calcium channel subunit alpha-1H0303
NAD(P)H dehydrogenase [quinone] 10005
Broad substrate specificity ATP-binding cassette transporter ABCG2045352
P53120012
Caspase-7370037
serine-protein kinase ATM isoform a150015
parathyroid hormone/parathyroid hormone-related peptide receptor precursor650065
caspase-3370037
lethal(3)malignant brain tumor-like protein 1 isoform I200020
P2X purinoceptor 30314
P2X purinoceptor 20123
Albumin0102137
Replicase polyprotein 1ab0512273
Reverse transcriptase/RNaseH 0171043
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial0303
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial0202
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial0202
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial0202
Solute carrier organic anion transporter family member 1B3043053
Solute carrier organic anion transporter family member 1B1045056
ATP-binding cassette sub-family C member 302030203
Multidrug resistance-associated protein 402080214
Bile salt export pump02920295
Steroid 17-alpha-hydroxylase/17,20 lyase0707
Steroid 21-hydroxylase0202
Steroid 17-alpha-hydroxylase/17,20 lyase 0404
Cytochrome P450 11B1, mitochondrial0606
Cytochrome P450 11B2, mitochondrial0505
Canalicular multispecific organic anion transporter 101980199
Solute carrier family 22 member 1 048058
Beta-2 adrenergic receptor0151228
Beta-1 adrenergic receptor019928
Beta-3 adrenergic receptor019827
Lactoylglutathione lyase015015
muscleblind-like protein 1 isoform 1610061
thyrotropin-releasing hormone receptor230023
Solute carrier family 22 member 6021022
UDP-glucuronosyltransferase 1A90309
Bile salt export pump042045
Cytochrome P450 2B10203
Cytochrome P450 1A10001
Myoglobin0101
Prostaglandin G/H synthase 1036239
Polyunsaturated fatty acid lipoxygenase ALOX15024024
UDP-glucuronosyltransferase 1-6014016
Arachidonate 5-lipoxygenase-activating protein0415
UDP-glucuronosyltransferase 1A1 024031
Prostaglandin G/H synthase 1060061
Prostaglandin G/H synthase 2057969
Cytochrome P450 2J2045046
toxin B0001
Chain A, TYROSYL-DNA PHOSPHODIESTERASE12600126
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Class Iii Chitinase Chia10101
Chain A, Carbonic anhydrase 130101
Chain A, Carbonic anhydrase II0202
Chain A, Carbonic anhydrase 20202
Chain A, Carbonic anhydrase 20202
Chain A, Carbonic anhydrase 20202
Chain A, Carbonic anhydrase 20202
Chain A, Carbonic anhydrase 20202
Chain A, Carbonic anhydrase 20202
Chain A, Carbonic anhydrase 20202
Chain A, Carbonic anhydrase 20202
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase0101
Chain B, Carbonic anhydrase0101
Chain A, Carbonic anhydrase 20101
Carbonic anhydrase 0005
Carbonic anhydrase 010010
GALC protein300030
Carbonic anhydrase 0606
Carbonic anhydrase 0707
Carbonic anhydrase0707
Carbonic anhydrase0404
Prolyl endopeptidase0303
Carbonic anhydrase-related protein 110102
Carbonic anhydrase 20303
Cathepsin B0202
Steryl-sulfatase0709
Cytochrome P450 2C8022024
Carbonic anhydrase 5A, mitochondrial0202
Serum paraoxonase/arylesterase 10909
Dipeptidyl peptidase 4019121
Endochitinase0101
Delta-type opioid receptor022228
Delta-type opioid receptor019426
Mu-type opioid receptor027637
Carbonic anhydrase018024
Kappa-type opioid receptor021326
Carbonic anhydrase0101
Corticosteroid 11-beta-dehydrogenase isozyme 10314
Carbonic anhydrase05012
Cholinesterase021123
Fatty-acid amide hydrolase 1010011
Carbonic anhydrase 20808
Glutamate receptor ionotropic, NMDA 2B129645
Squalene synthase0405
Neuronal acetylcholine receptor subunit alpha-706310
Carbonic anhydrase, alpha family 0808
Carbonic anhydrase 30909
Carbonic anhydrase04012
Carbonic anhydrase 0606
Sigma intracellular receptor 2013013
Delta carbonic anhydrase0606
Sigma non-opioid intracellular receptor 1020121
Renin0202
Carbonic anhydrase 05012
Endochitinase A10101
Multidrug resistance-associated protein 10101
Carbonic anhydrase 13013118
Carbonic anhydrase 407012
Acidic mammalian chitinase0101
Carbonic anhydrase 70101
Carbonic anhydrase 0505
Carbonic anhydrase 0101
Carbonic anhydrase 2, isoform A 0101
Free fatty acid receptor 30044
Free fatty acid receptor 20235
Tyrosine-protein kinase Lck0171936
Tyrosine-protein kinase Fyn0211839
Fibrinogen C domain-containing protein 10101
dopamine D1 receptor200020
D(1A) dopamine receptor600060
Histone deacetylase 3024024
Histone deacetylase 4022022
Histone deacetylase 1029029
Histone deacetylase 7021021
Histone deacetylase 2028028
Polyamine deacetylase HDAC10019019
Histone deacetylase 11 020020
Histone deacetylase 8025126
Histone deacetylase 6029029
Histone deacetylase 9021021
Histone deacetylase 5023023
Calpain small subunit 10101
Calpain-1 catalytic subunit0101
Cathepsin B012113
Calpain-1 catalytic subunit0101
Inositol monophosphatase 1570057
eyes absent homolog 2 isoform a120012
Rap guanine nucleotide exchange factor 3480048
Rap guanine nucleotide exchange factor 4280028
Transient receptor potential cation channel subfamily A member 1011418
integrase, partial0606
lens epithelium-derived growth factor p750606
hypothetical protein, conserved220022
Arginase 0707
Protein kinase C alpha type0505
Protein kinase C delta type0505
Protein kinase C epsilon type0505
Protein kinase C zeta type0505
Protein kinase C alpha type081726
Protein kinase C gamma type0505
Protein kinase C beta type0505
Prostaglandin G/H synthase 2022023
Protein kinase C eta type0505
Integrase 025126
Protein kinase C theta type0505
Histone deacetylase 60101
Leukotriene A-4 hydrolase0606
Proteasome subunit beta type-5023025
NAD-dependent protein deacetylase sirtuin-20628
NAD-dependent protein deacetylase sirtuin-105213
Nuclear receptor corepressor 20303
Solute carrier family 22 member 6018025
Chain A, MTA/SAH nucleosidase0101
Chain A, Ribosome-inactivating protein alpha-trichosanthin0011
Chain A, Ricin A chain0011
Chain A, Ribosome-inactivating protein 30011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
tumor susceptibility gene 101 protein100010
Cyclin-dependent kinase 10171634
Heat shock protein HSP 90-beta06413
Protein mono-ADP-ribosyltransferase PARP150404
Leucine-rich repeat serine/threonine-protein kinase 20268
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Structure of PAE2307 in complex with adenosine0011
Chain B, Structure of PAE2307 in complex with adenosine0011
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, tRNA (guanine-N(1)-)-methyltransferase0011
Chain A, Uncharacterized protein MJ08830011
signal transducer and activator of transcription 6, interleukin-4 induced3003
NPYLR7B0066
glycogen synthase kinase-3 beta isoform 10099
high affinity choline transporter 1 isoform a0404
Sodium/nucleoside cotransporter 10505
Calcium dependent protein kinase0101
Mitogen-activated protein kinase kinase kinase 70099
Sodium/nucleoside cotransporter 20505
Purine nucleoside phosphorylase0404
Epidermal growth factor receptor0411960
Phosphoglycerate kinase 1 0101
Adenosine deaminase0001
Avidin0011
Adenosine deaminase0001
Glyceraldehyde-3-phosphate dehydrogenase0505
Receptor tyrosine-protein kinase erbB-2018725
Insulin receptor071725
Phosphoglycerate kinase 20101
Heat shock protein HSP 90-alpha07816
Platelet-derived growth factor receptor beta091727
Heat shock 70 kDa protein 1A 0213
Heat shock cognate 71 kDa protein0022
Fibroblast growth factor receptor 1061724
Inosine-5'-monophosphate dehydrogenase 2041418
Endoplasmin0225
Inosine-5'-monophosphate dehydrogenase 1 0303
Fibroblast growth factor receptor 20067
Fibroblast growth factor receptor 40067
Fibroblast growth factor receptor 30067
Streptavidin0022
Adenosylhomocysteinase0003
Adenylate kinase 2, mitochondrial0203
Adenylate kinase isoenzyme 1 0203
Phosphatidylinositol 4-kinase alpha0506
Adenosine receptor A10314
Adenosine kinase001617
Adenosine deaminase 0001
Equilibrative nucleoside transporter 20404
Phosphatidylinositol 4-kinase type 2-beta0506
Histone-lysine N-methyltransferase, H3 lysine-79 specific0314
Equilibrative nucleoside transporter 10808
Phosphatidylinositol 4-kinase type 2-alpha0506
Solute carrier family 28 member 30707
Adenosine kinase0102
Phosphatidylinositol 4-kinase beta05612
5-methylthioadenosine/S-adenosylhomocysteine deaminase0002
Adenosine transporter 10001
Chain A, Heat Shock Protein 900011
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, Myosin Ie Heavy Chain0011
Chain A, Preprotein translocase secA0011
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Phosphoribosylformylglycinamidine synthase0101
Chain A, nucleoside diphosphate kinase A0011
Chain B, nucleoside diphosphate kinase A0011
Chain D, DNA polymerase III subunit gamma0011
Chain D, DNA polymerase III subunit gamma0011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A, Kinesin-like protein KIF110101
HPr kinase/phosphorylase0011
ATP-dependent molecular chaperone HSP820102
2-dehydropantoate 2-reductase0235
Endoplasmic reticulum chaperone BiP0112
Pyruvate kinase PKM 0001
Pyruvate kinase PKLR 0001
Heat shock cognate 71 kDa protein0011
5'-nucleotidase0404
Mu-type opioid receptor0451165
Delta-type opioid receptor032748
Kappa-type opioid receptor036853
Endoplasmin0224
P2Y purinoceptor 20022
P2X purinoceptor 10022
P2Y purinoceptor 10022
P2Y purinoceptor 10022
P2X purinoceptor 10112
P2X purinoceptor 40022
P2X purinoceptor 50011
P2X purinoceptor 60011
Heat shock protein 75 kDa, mitochondrial0202
P2Y purinoceptor 60011
P2Y purinoceptor 110022
P2Y purinoceptor 120415
Sensor protein kinase WalK0101
Chain A, Glycogen Phosphorylase B0011
Chain B, Glycogen Phosphorylase B0011
Chain A, ADP-dependent glucokinase0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, phosphodiesterase-nucleotide pyrophosphatase0101
Chain A, GLYCOGEN PHOSPHORYLASE B0011
Chain B, GLYCOGEN PHOSPHORYLASE B0011
Chain A, GLYCOGEN PHOSPHORYLASE B0011
2'-deoxynucleoside 5'-phosphate N-hydrolase 10101
2'-deoxynucleoside 5'-phosphate N-hydrolase 10101
5'-AMP-activated protein kinase subunit beta-20113
Transient receptor potential cation channel subfamily M member 20303
Alcohol dehydrogenase E chain0415
Alcohol dehydrogenase S chain0415
L-lactate dehydrogenase A chain0516
Adenylate kinase isoenzyme 10002
Fructose-1,6-bisphosphatase 10101
Alkaline phosphatase, tissue-nonspecific isozyme0809
Fructose-1,6-bisphosphatase 10303
Inosine-5'-monophosphate dehydrogenase0101
Proto-oncogene tyrosine-protein kinase Src0171734
Amine oxidase [flavin-containing] B015015
5'-nucleotidase0203
GTP:AMP phosphotransferase AK3, mitochondrial0001
5'-AMP-activated protein kinase subunit gamma-1012022
5'-AMP-activated protein kinase catalytic subunit alpha-201911
Adenylate kinase 2, mitochondrial001618
Glycine--tRNA ligase0101
5'-AMP-activated protein kinase catalytic subunit alpha-1012022
Adenosine deaminase-like protein0001
Protease 015626
Histamine H3 receptor1326
5'-AMP-activated protein kinase subunit gamma-30113
5'-AMP-activated protein kinase subunit gamma-2011618
5'-AMP-activated protein kinase subunit beta-10146
WRN150015
chaperonin-containing TCP-1 beta subunit homolog6006
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)430043
histone-lysine N-methyltransferase 2A isoform 2 precursor410041
pyruvate kinase PKM isoform b150015
Tyrosine-protein kinase JAK2091122
Ornithine decarboxylase150016
Tyrosine-protein kinase JAK1081929
Glutamate receptor ionotropic, NMDA 1 130746
Tyrosine-protein kinase JAK3010821
Glutamate receptor ionotropic, NMDA 2A 127541
Glutamate receptor ionotropic, NMDA 2C127542
Glutathione reductase, mitochondrial013017
Transcriptional activator protein LasR0101
Trypanothione reductase012017
Regulatory protein RhlR0203
Alanine racemase, biosynthetic0001
Proton-coupled amino acid transporter 1016017
Adenosine deaminase0001
60 kDa chaperonin017017
60 kDa heat shock protein, mitochondrial019019
10 kDa heat shock protein, mitochondrial019019
Thiosulfate sulfurtransferase019019
Beta-2 adrenergic receptor 0149
60 kDa chaperonin 019019
10 kDa chaperonin 019019
Beta-2 adrenergic receptor05613
Mineralocorticoid receptor 114724
Mineralocorticoid receptor0303
Solute carrier organic anion transporter family member 1A109017
Chain A, farnesyl pyrophosphate synthase0101
Acetylcholinesterase055257
Hypoxanthine-guanine phosphoribosyltransferase0303
Farnesyl pyrophosphate synthase 0707
Farnesyl pyrophosphate synthase 0303
Isopentenyl-diphosphate Delta-isomerase 1 0101
Interstitial collagenase010111
Stromelysin-109211
Farnesyl pyrophosphate synthase0101
Pepsin A0101
Renin-1 0101
Renin 0101
Cathepsin D 0101
Renin 0101
Protease 012416
Bile acid receptor07916
retinoic acid receptor alpha isoform 10202
retinoic acid receptor RXR-alpha isoform a0202
Retinoic acid receptor alpha05615
Retinoic acid receptor beta05615
Retinoic acid receptor alpha0336
Retinoic acid receptor gamma 06616
Retinoic acid receptor gamma0235
Retinoic acid receptor RXR-alpha071020
Retinoic acid receptor beta0235
Nuclear receptor subfamily 4 group A member 10033
Cellular retinoic acid-binding protein 20033
Retinoic acid receptor RXR-alpha0358
Retinoic acid receptor RXR-beta0549
Retinoic acid receptor RXR-beta0246
Retinoic acid receptor RXR-gamma0246
Cellular retinoic acid-binding protein 10304
Retinoic acid receptor RXR-gamma0549
Type-2 angiotensin II receptor0516
Cellular retinoic acid-binding protein 10033
Retinoic acid receptor RXR-alpha0011
Vpr190019
kelch-like ECH-associated protein 10004
Gag-Pol polyprotein0808
Apoptosis regulator Bcl-209211
Glutamate receptor 1126625
Glutamate receptor 3126625
Glutamate receptor 4126625
Induced myeloid leukemia cell differentiation protein Mcl-1012113
RmtA0101
Protein arginine N-methyltransferase 10303
phosphoglycerate kinase150015
Phosphoglycerate mutase 10202
Tyrosine-protein phosphatase 10303
Pyruvate kinase PKLR0202
RGS126006
Transient receptor potential cation channel subfamily V member 10639
Procathepsin L0171936
Transient receptor potential cation channel subfamily A member 10055
Transient receptor potential cation channel subfamily V member 105615
Cysteine protease 0202
Mitochondrial 2-oxodicarboxylate carrier0101
Thioredoxin reductase 1, cytoplasmic0303
Bifunctional epoxide hydrolase 2018018
5-lipoxygenase 0101
P2Y purinoceptor 120707
Thioredoxin reductase 2, mitochondrial0202
transcriptional regulator ERG isoform 3300030
Hypoxanthine-guanine phosphoribosyltransferase0105
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase 0101
Nuclear receptor ROR-gamma0101
Xanthine dehydrogenase/oxidase019123
Purine nucleoside phosphorylase0022
Shiga toxin subunit A0202
Histamine H3 receptor0418
5-hydroxytryptamine receptor 3A0808
Potassium voltage-gated channel subfamily H member 201030105
Botulinum neurotoxin type A 0505
Neutrophil cytosol factor 10303
Nitric oxide synthase, endothelial0404
Nitric oxide synthase, brain0719
Nitric oxide synthase, brain 0507
Nitric oxide synthase, inducible0519
Tyrosine-protein kinase 0011
3-hydroxy-3-methylglutaryl-coenzyme A reductase0202
phospholipase A2 precursor0101
cysteine protease ATG4B isoform a0101
DNA dC->dU-editing enzyme APOBEC-3F isoform a140014
Free fatty acid receptor 10168
Prostaglandin G/H synthase 1 017020
Nuclear receptor subfamily 1 group I member 2041216
Trypsin0607
Coagulation factor VII0808
Tissue factor011011
Free fatty acid receptor 40033
Carboxylic ester hydrolase 0101
Cytochrome P450 3A60101
UDP-glucuronosyltransferase 2B7013025
Substance-K receptor030030
UDP-glucuronosyltransferase 1A4012022
Thromboxane-A synthase 017017
Aryl hydrocarbon receptor0101
Multidrug resistance-associated protein 1 015122
UDP-glucuronosyltransferase 2B10 011011
Gamma-aminobutyric acid receptor subunit alpha-10191231
Gamma-aminobutyric acid receptor subunit gamma-20181129
Cholecystokinin receptor type A1708
Gamma-aminobutyric acid receptor subunit alpha-5017623
Gamma-aminobutyric acid receptor subunit alpha-3017623
Gamma-aminobutyric acid receptor subunit alpha-2017522
Gamma-aminobutyric acid receptor subunit beta-2017926
Cholecystokinin receptor type A0606
Prostaglandin E2 receptor EP3 subtype0404
Prostaglandin E2 receptor EP4 subtype0325
Prostaglandin E2 receptor EP1 subtype0303
Prostacyclin receptor07411
Nuclear receptor subfamily 4 group A member 20077
Solute carrier organic anion transporter family member 2A10207
Nuclear receptor subfamily 4 group A member 20011
Nuclear receptor subfamily 4 group A member 20011
Prostaglandin E2 receptor EP2 subtype0314
Solute carrier organic anion transporter family member 2A10104
Solute carrier organic anion transporter family member 2B10203
Solute carrier organic anion transporter family member 3A10001
neuropeptide S receptor isoform A470047
Cannabinoid receptor 1020836
Cannabinoid receptor 2 017833
Cannabinoid receptor 205510
Mcl-10606
Valosin-containing protein0202
Spike glycoprotein071825
Replicase polyprotein 1ab0181937
hypothetical protein SA14220202
Gamma-aminobutyric acid receptor subunit pi013013
Gamma-aminobutyric acid receptor subunit delta013013
Transmembrane protease serine 2071825
Group 10 secretory phospholipase A20101
Phospholipase A20101
Amyloid-beta precursor protein732343
Estrogen receptor04813
Neutrophil elastase016016
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-10101
Poly [ADP-ribose] polymerase 10718
Replicase polyprotein 1a0181836
Replicase polyprotein 1ab0101828
Phospholipase A2, membrane associated0102
Matrix metalloproteinase-9013114
Vascular endothelial growth factor A0011
Gamma-aminobutyric acid receptor subunit beta-1015318
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-10101
Gamma-aminobutyric acid receptor subunit beta-3017522
D(3) dopamine receptor061574
Cytosolic phospholipase A20101
Gamma-aminobutyric acid receptor subunit alpha-4015217
Placenta growth factor0011
Gamma-aminobutyric acid receptor subunit epsilon013013
Delta-type opioid receptor0101
5-hydroxytryptamine receptor 1D0101
Gamma-aminobutyric acid receptor subunit alpha-6015217
Estrogen receptor beta03812
Gamma-aminobutyric acid receptor subunit gamma-1013013
Gamma-aminobutyric acid receptor subunit gamma-3013013
Angiotensin-converting enzyme 2 0111930
Poly [ADP-ribose] polymerase 20202
Gamma-aminobutyric acid receptor subunit theta013013
M1-family alanyl aminopeptidase0303
Solute carrier organic anion transporter family member 2B1 010016
Thrombopoietin receptor0011
Sodium channel protein type 5 subunit alpha022022
Potassium voltage-gated channel subfamily D member 30404
Chain U, UROKINASE-TYPE PLASMINOGEN ACTIVATOR0101
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR0101
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR0101
Membrane primary amine oxidase 0202
Prothrombin08413
Coagulation factor X012012
Plasminogen0628
Urokinase-type plasminogen activator0606
Tissue-type plasminogen activator0505
Cationic trypsin0707
Coagulation factor XI0101
Plasma kallikrein03111
Vitamin K-dependent protein C0202
Urokinase-type plasminogen activator0404
Trypsin-10606
Trypsin-20606
Sodium/hydrogen exchanger 10101
Sodium/hydrogen exchanger 10303
Sodium/hydrogen exchanger 30202
Trypsin-30606
Amiloride-sensitive sodium channel subunit alpha0101
Sodium/hydrogen exchanger 20202
Acid-sensing ion channel 10303
Sodium/hydrogen exchanger 50202
Solute carrier family 22 member 1021026
Solute carrier family 22 member 2019022
Acid-sensing ion channel 30101
Sodium/hydrogen exchanger0101
Chain A, PLASMINOGEN0022
Chain A, PLASMINOGEN0022
Chain A, Apolipoprotein0011
Sterol O-acyltransferase 10505
Cholesterol side-chain cleavage enzyme, mitochondrial 0112
Triosephosphate isomerase0404
Cholesterol side-chain cleavage enzyme, mitochondrial0101
Ribosyldihydronicotinamide dehydrogenase [quinone]0111829
Aromatase0213
Cytochrome P450 11B2, mitochondrial0202
Lysyl oxidase homolog 20101
Protein-lysine 6-oxidase0101
Lysyl oxidase homolog 20101
Lysyl oxidase homolog 30202
Lysyl oxidase homolog 40202
Lysyl oxidase homolog 20202
Dihydrofolate reductase014016
Dihydrofolate reductase0507
Dihydrofolate reductase0507
Dihydrofolate reductase07310
Folylpolyglutamate synthase, mitochondrial0206
Solute carrier organic anion transporter family member 1A305011
Folylpolyglutamate synthase, mitochondrial0106
Nicotinate phosphoribosyltransferase010010
ORF730078
Voltage-dependent L-type calcium channel subunit alpha-1C011011
Solute carrier organic anion transporter family member 1A408017
Voltage-dependent L-type calcium channel subunit alpha-1F023023
Lysine-specific demethylase PHF20101
Thyroid hormone receptor alpha0101
ATP-dependent translocase ABCB1017017
Muscarinic acetylcholine receptor M2049761
Muscarinic acetylcholine receptor M4045351
Muscarinic acetylcholine receptor M5047252
Alpha-2A adrenergic receptor074884
Thyroid hormone receptor alpha05510
Thyroid hormone receptor beta05510
Muscarinic acetylcholine receptor M1055869
Lethal factor0303
Alpha-2B adrenergic receptor070678
Thyroid hormone receptor beta0303
Muscarinic acetylcholine receptor M3050457
ATP-dependent translocase ABCB1018524
D(4) dopamine receptor025233
Carnitine O-palmitoyltransferase 2, mitochondrial0303
Histamine H2 receptor029231
Endothelin-1 receptor0516
Lysine-specific demethylase 5A0404
B2 bradykinin receptor0404
Melanocortin receptor 40606
C-8 sterol isomerase0707
Melanocortin receptor 5010010
Sodium channel protein type 1 subunit alpha0909
Sodium channel protein type 4 subunit alpha012015
Squalene synthase0102
C-C chemokine receptor type 20909
Melanocortin receptor 30606
Carnitine O-palmitoyltransferase 1, liver isoform0303
C-C chemokine receptor type 40505
Sodium channel protein type 7 subunit alpha0707
Voltage-dependent L-type calcium channel subunit alpha-1D 023023
Voltage-dependent L-type calcium channel subunit alpha-1S023023
Squalene monooxygenase0101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0819
Sodium channel protein type 9 subunit alpha012012
Lysine-specific demethylase 7A0101
Carnitine O-palmitoyltransferase 1, muscle isoform0202
Sodium channel protein type 2 subunit alpha010010
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0459
Sodium channel protein type 3 subunit alpha011011
Sodium channel protein type 11 subunit alpha0707
Histone lysine demethylase PHF80101
Sodium channel protein type 8 subunit alpha0707
Sodium channel protein type 10 subunit alpha0808
pyruvate kinase220022
Endothelin receptor type B6107
Endothelin-1 receptor6107
Inhibitor of nuclear factor kappa-B kinase subunit epsilon011718
G-protein coupled receptor 350141327
Serine/threonine-protein kinase TBK1041721
NEDD8-activating enzyme E1 regulatory subunit isoform a0202
NEDD8-conjugating enzyme Ubc120202
Potassium channel subfamily K member 207815
Alpha-2C adrenergic receptor053661
Voltage-dependent L-type calcium channel subunit alpha-1C0707
Potassium channel subfamily K member 2 0303
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase SHV-10001
Beta-lactamase SHV-10001
Beta-lactamase0001
Solute carrier family 15 member 10808
Solute carrier family 15 member 10404
B2 metallo-beta-lactamase 0001
Solute carrier family 15 member 20606
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 15 member 20505
Beta-lactamase 0001
Beta-lactamase 0001
Synaptojanin-20303
Synaptojanin-10303
Chain A, Mutant Al2 6e7p9g0011
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase type 20001
Metallo-beta-lactamase VIM-11 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0001
Metallo-beta-lactamase0001
Beta-lactamase 0001
Beta-lactamase OXA-70003
Angiopoietin-1 receptor03811
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-130102
Efflux transporter 0102
Beta-lactamase 0001
Beta-lactamase Toho-10001
Beta-lactamase 0102
Class D beta-lactamase0002
Metallo-beta-lactamase0001
Beta-lactamase 0001
Beta-lactamase 0113
Metallo-b-lactamase 0002
Carbapenem-hydrolyzing beta-lactamase KPC0001
Beta-lactamase class B VIM-2 0002
Beta-lactamase VIM-1 0102
Fatty-acid amide hydrolase 10707
Fatty-acid amide hydrolase 10102
Potassium channel subfamily K member 30303
Fatty acid-binding protein, liver0505
Cannabinoid receptor 108210
Corticotropin-releasing factor receptor 20202
Lanosterol 14-alpha demethylase013114
Cannabinoid receptor 20415
Transient receptor potential cation channel subfamily V member 20628
Amine oxidase [flavin-containing] A 011112
Chain A, Androgen receptor0101
Chain A, Androgen receptor0101
Chain A, Androgen receptor0101
Chain A, Androgen receptor0101
Chain A, Androgen receptor0101
Nuclear factor NF-kappa-B p105 subunit011012
Signal transducer and activator of transcription 30415
Hexokinase-20101
Beta-glucuronidase0303
Cholinesterase018119
Gastrin/cholecystokinin type B receptor1327
Testosterone 17-beta-dehydrogenase 3010010
Chain A, retinol dehydratase0101
Glucose-6-phosphate 1-dehydrogenase015117
G-protein coupled bile acid receptor 1041822
Acetylcholinesterase025026
Atrial natriuretic peptide receptor 30202
Type-1A angiotensin II receptor 1528
Type-1 angiotensin II receptor0011
Type-1B angiotensin II receptor1708
Type-1 angiotensin II receptor09417
Type-2 angiotensin II receptor1708
Chain A, BCL-2-RELATED PROTEIN A10046
PAX80005
Hsf1 protein00810
hepatitis C virus polyprotein1001
heat shock protein 900033
caspase recruitment domain family, member 150202
receptor-interacting serine/threonine-protein kinase 2 isoform 10202
bcl-2-like protein 11 isoform 10044
Bcl-2-like protein 110102
Glucose transporter0303
Hexose transporter 1 0303
Solute carrier family 2, facilitated glucose transporter member 10707
Beta lactamase (plasmid)0505
PINK1130013
NAD-dependent protein deacylase sirtuin-5, mitochondrial0809
Apelin receptor0112
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0202
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0202
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0202
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0202
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0202
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0202
Chain A, Transthyretin0055
Chain A, Transthyretin0055
Chain A, Transthyretin0055
Chain A, Transthyretin0055
Chain B, Transthyretin0055
Chain A, Transthyretin0055
Chain B, Transthyretin0055
Chain A, Casein kinase II subunit alpha0202
Chain A, Casein kinase II subunit alpha0202
Chain A, Casein Kinase Ii Subunit Alpha0202
Neuraminidase 022022
hemoglobin subunit beta120012
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 15005
ubiquitin carboxyl-terminal hydrolase 2 isoform a370037
Aldo-keto reductase family 1 member B10020020
G2/mitotic-specific cyclin-B2010011
Poly [ADP-ribose] polymerase tankyrase-10415
Lysozyme C-10202
Myeloperoxidase012012
Beta-glucuronidase0303
Seed linoleate 13S-lipoxygenase-1014022
Sialidase0606
Angiotensin-converting enzyme034034
Cystic fibrosis transmembrane conductance regulator0167
G2/mitotic-specific cyclin-B1016017
Urease subunit alpha013013
Aldo-keto reductase family 1 member B1039040
G2/mitotic-specific cyclin-B0707
Mucin-10101
Glycogen synthase kinase-3 beta0808
Substance-P receptor022026
Receptor-type tyrosine-protein kinase FLT30211738
Acetylcholinesterase0507
Peroxisome proliferator-activated receptor gamma011314
Homeobox protein Nkx-2.5 0202
Tyrosine-protein kinase SYK0102333
Estrogen receptor0022
Death-associated protein kinase 1010616
Mitogen-activated protein kinase 100171835
Urease subunit beta013013
Disintegrin and metalloproteinase domain-containing protein 17276033
Lactoperoxidase0309
MO15-related protein kinase Pfmrk 0808
Cyclin-dependent kinase 6081624
Cyclin-dependent-like kinase 5 0121729
Cyclin homolog0606
Transcription factor GATA-4 0202
Cyclin-dependent kinase 5 activator 1011011
Substance-K receptor015015
Casein kinase II subunit alpha 3018119
Inositol polyphosphate multikinase0606
G2/mitotic-specific cyclin-B3010011
Enoyl-acyl-carrier protein reductase 014014
NACHT, LRR and PYD domains-containing protein 3 0303
Myocilin0011
Cyclin-dependent kinase 10707
Prenyltransferase homolog0005
Poly [ADP-ribose] polymerase tankyrase-20516
MAP kinase-interacting serine/threonine-protein kinase 204610
Carboxylic ester hydrolase 0405
NADPH oxidase 40404
Estrogen receptor beta0022
Inositol hexakisphosphate kinase 20606
Short transient receptor potential channel 50606
Sialidase-2011011
2,3-bisphosphoglycerate-independent phosphoglycerate mutase8008
Chain A, Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor)0101
Coagulation factor X0101
Tryptophan 5-hydroxylase 10404
D(1B) dopamine receptor08012
D(1B) dopamine receptor014014
D(4) dopamine receptor016117
E3 ubiquitin-protein ligase Mdm20303
D0808
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN0011
Chain A, SERUM ALBUMIN0022
Chain A, SERUM ALBUMIN0022
Calmodulin 0269
Cytosolic phospholipase A2 gamma0202
Polyphenol oxidase 10101
Taste receptor type 2 member 160023
Muscarinic acetylcholine receptor M1022834
Muscarinic acetylcholine receptor M30211035
Muscarinic acetylcholine receptor M4020832
Muscarinic acetylcholine receptor M5020832
Muscarinic acetylcholine receptor M2022835
Muscarinic acetylcholine receptor M10237
Muscarinic acetylcholine receptor09212
Muscarinic acetylcholine receptor M30125
Muscarinic acetylcholine receptor M20115
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0033
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0033
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0033
Nitric oxide synthase, endothelial0204
Nitric oxide synthase, inducible0809
Cationic amino acid transporter 30202
Vasopressin V2 receptor05410
Oxytocin receptor0459
Vasopressin V1a receptor0134
Vasopressin V1a receptor010515
Vasopressin V1b receptor0347
Vasopressin V2 receptor0011
Vasopressin V1b receptor0214
Translocator protein0203
Oxytocin receptor0213
Vasopressin V2 receptor 0325
Integrin beta-10808
Integrin alpha-50606
Integrin beta-50303
Integrin alpha-20101
Integrin alpha-30101
Integrin beta0213
Glycoprotein IIb0213
5-hydroxytryptamine receptor 3E0505
Solute carrier family 22 member 2021027
5-hydroxytryptamine receptor 3A0213
5-hydroxytryptamine receptor 3B0505
Histamine H1 receptor06513
Histamine H1 receptor036543
3-hydroxy-3-methylglutaryl-coenzyme A reductase 011011
5-hydroxytryptamine receptor 3D0505
Multidrug and toxin extrusion protein 2015015
5-hydroxytryptamine receptor 3C0505
Multidrug and toxin extrusion protein 1034034
Histamine H3 receptor012215
Dihydroorotate dehydrogenase 012012
Chain A, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, gamma isoform0101
Chain A, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, gamma isoform0101
Dual specificity protein kinase CLK1041620
Dual specificity tyrosine-phosphorylation-regulated kinase 1A071724
Dual specificity tyrosine-phosphorylation-regulated kinase 20268
CDGSH iron-sulfur domain-containing protein 1015015
Dual specificity tyrosine-phosphorylation-regulated kinase 1B04913
Chain A, Hyaluronidase, phage associated0101
Pancreatic alpha-amylase0202
Albumin0304
Urease0304
Prolyl 4-hydroxylase subunit alpha-10001
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20034
Egl nine homolog 10146
Prolyl hydroxylase EGLN30034
Hypoxia-inducible factor 1-alpha inhibitor0203
Solute carrier family 23 member 10101
Pancreatic alpha-amylase0608
Tyrosine-protein phosphatase non-receptor type 2010010
DNA repair protein RAD52 homolog0303
Metabotropic glutamate receptor 60135
Excitatory amino acid transporter 40202
Glutamate transporter homolog0011
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0101
Excitatory amino acid transporter 10304
Excitatory amino acid transporter 20304
Excitatory amino acid transporter 30304
Metabotropic glutamate receptor 10124
Metabotropic glutamate receptor 20124
Carbonic anhydrase-like protein, putative0009
Glutamate receptor ionotropic, NMDA 2D126540
Glutamate receptor ionotropic, NMDA 3B126540
Glutamate receptor ionotropic, NMDA 3A126540
Chain A, Phospholipase A2 isoform 30011
GTP-binding protein (rab7)0044
ras protein, partial0044
Rac1 protein0044
cell division cycle 42 (GTP binding protein, 25kDa), partial0044
Prostaglandin-H2 D-isomerase0202
Prostaglandin G/H synthase 2 09011
Fatty acid-binding protein, liver011213
Glutathione hydrolase 1 proenzyme0101
Urotensin-2 receptor0202
4-aminobutyrate aminotransferase, mitochondrial0202
Ras-related protein Rab-2A0044
Rho-associated protein kinase 20404
Sigma non-opioid intracellular receptor 1013417
Insulin receptor 0606
Dipeptidyl peptidase 40202
Atrial natriuretic peptide receptor 10112
Atrial natriuretic peptide receptor 1 0011
cystic fibrosis transmembrane conductance regulator0101
short transient receptor potential channel 6 isoform 10033
Muscarinic acetylcholine receptor M40315
cGMP-specific 3',5'-cyclic phosphodiesterase0202
Thromboxane A2 receptor 0328
Sodium/bile acid cotransporter010112
Leukotriene B4 receptor 20124
Fatty acid synthase0606
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
Leukotriene C4 synthase0066
tyrosine-protein kinase Yes270027
Bone morphogenetic protein receptor type-1B011718
Cell division cycle 7-related protein kinase001010
Serine/threonine-protein kinase 250066
ATP-dependent RNA helicase DDX3X001616
Pyridoxal kinase001617
Citron Rho-interacting kinase011718
Serine/threonine-protein kinase RIO30066
Dual specificity mitogen-activated protein kinase kinase 70178
Serine/threonine-protein kinase Chk1011718
Inhibitor of nuclear factor kappa-B kinase subunit beta06613
Peripheral plasma membrane protein CASK0066
Aurora kinase A051823
Cyclin-G-associated kinase031821
Serine/threonine-protein kinase DCLK10066
Inhibitor of nuclear factor kappa-B kinase subunit alpha0369
Muscle, skeletal receptor tyrosine-protein kinase0167
Ephrin type-B receptor 6001717
Peroxisomal acyl-coenzyme A oxidase 3001616
3-phosphoinositide-dependent protein kinase 10268
Mitogen-activated protein kinase kinase kinase 130066
Death-associated protein kinase 30167
Receptor-interacting serine/threonine-protein kinase 2031720
Mitotic checkpoint serine/threonine-protein kinase BUB1001414
NUAK family SNF1-like kinase 10369
Dynamin-like 120 kDa protein, mitochondrial001616
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma0066
Eukaryotic translation initiation factor 5B0099
Rho-associated protein kinase 2061723
Serine/threonine-protein kinase ULK1001717
Serine/threonine-protein kinase/endoribonuclease IRE1011718
Ribosomal protein S6 kinase alpha-5041822
U5 small nuclear ribonucleoprotein 200 kDa helicase001616
Ribosomal protein S6 kinase alpha-4001919
Serine/threonine-protein kinase 16001717
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma0066
Serine/threonine-protein kinase PAK 30066
Cyclin-dependent kinase-like 5001212
Serine/threonine-protein kinase 17B0167
Serine/threonine-protein kinase 10011718
Serine/threonine-protein kinase D3031720
Cyclin-dependent kinase 140066
Structural maintenance of chromosomes protein 2001515
Mitogen-activated protein kinase kinase kinase 6001616
Serine/threonine-protein kinase OSR10066
Mitogen-activated protein kinase kinase kinase kinase 4001717
Serine/threonine-protein kinase LATS1001717
Serine/threonine-protein kinase PAK 4001717
Serine/threonine-protein kinase Chk20066
Tyrosine-protein kinase ABL10142038
RAF proto-oncogene serine/threonine-protein kinase04610
High affinity nerve growth factor receptor011617
Guanine nucleotide-binding protein G(i) subunit alpha-2001313
ADP/ATP translocase 2001616
Protein kinase C beta type051621
Glycogen phosphorylase, liver form011617
Tyrosine-protein kinase Fes/Fps001818
Macrophage colony-stimulating factor 1 receptor05611
Adenine phosphoribosyltransferase001111
Tyrosine-protein kinase Yes0101727
Tyrosine-protein kinase Lyn031720
Proto-oncogene tyrosine-protein kinase receptor Ret061723
Insulin-like growth factor 1 receptor041721
Signal recognition particle receptor subunit alpha001515
Cytochrome c1, heme protein, mitochondrial001616
Tyrosine-protein kinase HCK041721
Proto-oncogene tyrosine-protein kinase ROS0178
Tyrosine-protein kinase Fgr011011
Wee1-like protein kinase 20066
Uncharacterized serine/threonine-protein kinase SBK30066
Serine/threonine-protein kinase A-Raf001515
Mast/stem cell growth factor receptor Kit07714
Glycogen phosphorylase, brain form001515
Breakpoint cluster region protein061828
DNA topoisomerase 2-alpha0101233
Cyclin-dependent kinase 4071724
ADP/ATP translocase 3001616
cAMP-dependent protein kinase type II-alpha regulatory subunit001515
Insulin receptor-related protein0066
Serine/threonine-protein kinase B-raf071724
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform001717
Platelet-derived growth factor receptor alpha06713
Tyrosine-protein kinase Fer001717
cAMP-dependent protein kinase catalytic subunit alpha091726
Vascular endothelial growth factor receptor 1 0369
General transcription and DNA repair factor IIH helicase subunit XPD001616
Interferon-induced, double-stranded RNA-activated protein kinase0369
Ras-related protein Rab-6A001515
Serine/threonine-protein kinase MAK0066
Cyclin-dependent kinase 11B0066
Ephrin type-A receptor 1001414
Receptor tyrosine-protein kinase erbB-30268
Multifunctional protein ADE2001616
cAMP-dependent protein kinase catalytic subunit gamma071522
cAMP-dependent protein kinase catalytic subunit beta071724
Ferrochelatase, mitochondrial001616
Ribosomal protein S6 kinase beta-1011718
Protein kinase C eta type0369
Beta-adrenergic receptor kinase 1001919
Probable ATP-dependent RNA helicase DDX6001616
Activin receptor type-2A0066
MAP/microtubule affinity-regulating kinase 3001717
Deoxycytidine kinase001621
Mitogen-activated protein kinase 1071724
Ephrin type-A receptor 2041721
Ephrin type-A receptor 30167
Ephrin type-A receptor 80066
Ephrin type-B receptor 2021719
Leukocyte tyrosine kinase receptor0077
Non-receptor tyrosine-protein kinase TYK2052027
UMP-CMP kinase 0088
Phosphatidylethanolamine-binding protein 1001111
Wee1-like protein kinase001717
Heme oxygenase 2001616
Tyrosine-protein kinase receptor UFO0268
Mitogen-activated protein kinase 40066
S-adenosylmethionine synthase isoform type-2001515
DnaJ homolog subfamily A member 1001616
RAC-alpha serine/threonine-protein kinase081826
RAC-beta serine/threonine-protein kinase021820
G protein-coupled receptor kinase 40066
Dual specificity protein kinase TTK001414
DNA replication licensing factor MCM4001515
Myosin-10001212
Tyrosine-protein kinase receptor Tie-10066
Vascular endothelial growth factor receptor 30369
Vascular endothelial growth factor receptor 2011617
Dual specificity mitogen-activated protein kinase kinase 2051722
Bone morphogenetic protein receptor type-1A011718
Activin receptor type-1B011718
TGF-beta receptor type-1031720
Serine/threonine-protein kinase receptor R30178
TGF-beta receptor type-2011718
Electron transfer flavoprotein subunit beta001111
Tyrosine-protein kinase CSK051722
Glycine--tRNA ligase001616
Protein kinase C iota type031720
Exosome RNA helicase MTR4001616
Megakaryocyte-associated tyrosine-protein kinase0066
Tyrosine-protein kinase Tec031720
Tyrosine-protein kinase TXK03710
Tyrosine-protein kinase ABL2011718
Tyrosine-protein kinase FRK011718
G protein-coupled receptor kinase 6011112
Tyrosine-protein kinase ZAP-700066
26S proteasome regulatory subunit 6B021618
Mitogen-activated protein kinase 8041822
Mitogen-activated protein kinase 9021820
Dual specificity mitogen-activated protein kinase kinase 401910
Dual specificity mitogen-activated protein kinase kinase 3001717
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha101314
Casein kinase I isoform alpha041620
Casein kinase I isoform delta041721
MAP kinase-activated protein kinase 2031720
Cyclin-dependent kinase 80066
Elongation factor Tu, mitochondrial001616
Choline-phosphate cytidylyltransferase A0077
Cysteine--tRNA ligase, cytoplasmic001313
Casein kinase I isoform epsilon041822
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial001616
Dual specificity protein kinase CLK2021416
Dual specificity protein kinase CLK3011415
Cyclin-dependent kinase 7031720
Cyclin-dependent kinase 9051722
Ras-related protein Rab-27A001414
Tyrosine-protein kinase Blk04711
Interleukin-1 receptor-associated kinase 1001717
Ribosomal protein S6 kinase alpha-3021820
Cytoplasmic tyrosine-protein kinase BMX04711
cAMP-dependent protein kinase catalytic subunit PRKX0077
Serine/threonine-protein kinase Nek2011718
Serine/threonine-protein kinase Nek3001717
Serine/threonine-protein kinase Nek40066
Dual specificity mitogen-activated protein kinase kinase 6001717
LIM domain kinase 1011718
LIM domain kinase 2011718
Tyrosine--tRNA ligase, cytoplasmic001616
Ephrin type-B receptor 3001717
Ephrin type-A receptor 5001717
Ephrin type-B receptor 4031720
Ephrin type-B receptor 10066
Ephrin type-A receptor 4001717
Hormonally up-regulated neu tumor-associated kinase0066
Serine/threonine-protein kinase SIK10268
Receptor-interacting serine/threonine-protein kinase 40066
Ras-related protein Rab-10001515
Cell division control protein 2 homolog0066
Actin-related protein 3001616
Actin-related protein 2001414
Calcium-dependent protein kinase 10066
GTP-binding nuclear protein Ran001616
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta0066
SRSF protein kinase 20066
Casein kinase I isoform gamma-2011617
Mitogen-activated protein kinase kinase kinase 90066
Serine/threonine-protein kinase PknB0066
Cyclin-dependent kinase 3001616
Cyclin-dependent kinase-like 10066
Cyclin-dependent kinase 16001717
Cyclin-dependent kinase 17001616
ATP-dependent 6-phosphofructokinase, platelet type001515
Protein kinase C epsilon type06612
Dual specificity mitogen-activated protein kinase kinase 1071724
Mitogen-activated protein kinase kinase kinase 100066
DNA topoisomerase 2-beta021727
Protein kinase C theta type031619
Activin receptor type-1011718
Macrophage-stimulating protein receptor011718
Focal adhesion kinase 1051823
Protein kinase C zeta type04812
Protein kinase C delta type041721
Tyrosine-protein kinase BTK071825
Tyrosine-protein kinase receptor TYRO30167
Cyclin-dependent kinase 180088
Activated CDC42 kinase 1011718
Epithelial discoidin domain-containing receptor 1031821
Tyrosine-protein kinase ITK/TSK04711
Myotonin-protein kinase0268
Mitogen-activated protein kinase kinase kinase kinase 2001717
Mitogen-activated protein kinase kinase kinase 120066
Tyrosine-protein kinase Mer021113
Serine/threonine-protein kinase 4001717
Serine/threonine-protein kinase PAK 10268
Dual specificity mitogen-activated protein kinase kinase 5001717
Mitogen-activated protein kinase 7001717
Serine/threonine-protein kinase PAK 2001515
Serine/threonine-protein kinase 3001717
Mitogen-activated protein kinase kinase kinase 1001717
cGMP-dependent protein kinase 20066
Integrin-linked protein kinase001515
Rho-associated protein kinase 1061723
Non-receptor tyrosine-protein kinase TNK1001717
Serine/threonine-protein kinase PRP4 homolog0066
Receptor-interacting serine/threonine-protein kinase 10178
Calcium/calmodulin-dependent protein kinase type II subunit beta0167
Calcium/calmodulin-dependent protein kinase type II subunit gamma001717
Calcium/calmodulin-dependent protein kinase type II subunit delta001717
Activin receptor type-2B001717
Bone morphogenetic protein receptor type-2011718
Protein-tyrosine kinase 6021719
cGMP-dependent protein kinase 1 011718
Cyclin-dependent kinase 13001717
Calcium/calmodulin-dependent protein kinase type 10066
Protein-tyrosine kinase 2-beta021820
Maternal embryonic leucine zipper kinase011718
Structural maintenance of chromosomes protein 1A001414
Chromodomain-helicase-DNA-binding protein 4001515
Peroxisomal acyl-coenzyme A oxidase 1001111
Serine/threonine-protein kinase D10369
Serine/threonine-protein kinase 380088
Receptor tyrosine-protein kinase erbB-403710
Ribosomal protein S6 kinase alpha-20066
Ephrin type-A receptor 7001515
Delta(24)-sterol reductase001515
Ribosomal protein S6 kinase alpha-1041721
Dual specificity testis-specific protein kinase 1001414
Myosin light chain kinase, smooth muscle051722
Serine/threonine-protein kinase STK11001717
Rhodopsin kinase GRK10066
NT-3 growth factor receptor0066
Serine/threonine-protein kinase N1021719
Serine/threonine-protein kinase N2021719
Calcium/calmodulin-dependent protein kinase type IV001717
Mitogen-activated protein kinase kinase kinase 11011718
BDNF/NT-3 growth factors receptor0167
Mitogen-activated protein kinase 60066
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform0066
Discoidin domain-containing receptor 2031720
AP2-associated protein kinase 1011718
Myosin light chain kinase 3001616
Serine/threonine-protein kinase SBK10066
Mitogen-activated protein kinase kinase kinase 190066
Putative heat shock protein HSP 90-beta 2001616
Serine/threonine-protein kinase TNNI3K0066
Serine/threonine-protein kinase MRCK alpha001717
Serine/threonine-protein kinase MRCK gamma001616
Acyl-CoA dehydrogenase family member 10001616
Serine/threonine-protein kinase Nek50066
Serine/threonine-protein kinase N3001212
Serine/threonine-protein kinase ULK3001717
Dual serine/threonine and tyrosine protein kinase0066
Mitogen-activated protein kinase kinase kinase 150066
Uncharacterized protein FLJ45252001616
Acyl-CoA dehydrogenase family member 11001414
Serine/threonine-protein kinase/endoribonuclease IRE2001616
Serine/threonine-protein kinase MARK2001717
ATP-dependent RNA helicase DHX300099
Serine/threonine-protein kinase TAO1001717
STE20-related kinase adapter protein alpha001515
Myosin-14001414
AarF domain-containing protein kinase 1001616
Serine/threonine-protein kinase tousled-like 20066
Serine/threonine-protein kinase 32C0066
ATP-dependent RNA helicase DDX42001212
Serine/threonine-protein kinase VRK20066
Myosin light chain kinase family member 40066
Homeodomain-interacting protein kinase 10066
Calcium/calmodulin-dependent protein kinase type 1D0066
Mitogen-activated protein kinase kinase kinase kinase 3001717
Cyclin-dependent kinase-like 30066
MAP kinase-activated protein kinase 5031619
Serine/threonine-protein kinase BRSK20077
Serine/threonine-protein kinase NIM10066
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B0077
Serine/threonine-protein kinase ULK20066
Misshapen-like kinase 1001212
Serine/threonine-protein kinase DCLK20066
Calcium/calmodulin-dependent protein kinase kinase 10066
Casein kinase I isoform alpha-like0066
Homeodomain-interacting protein kinase 40066
Myosin-IIIa0066
Ankyrin repeat and protein kinase domain-containing protein 10066
Serine/threonine-protein kinase Nek110066
Atypical kinase COQ8A, mitochondrial001818
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma001717
Mitogen-activated protein kinase 15001717
Serine/threonine-protein kinase Nek9001717
Serine/threonine-protein kinase BRSK10066
Serine/threonine-protein kinase 350066
Serine/threonine-protein kinase Nek7001313
Rhodopsin kinase GRK70066
Serine/threonine-protein kinase 32A0066
Myosin-IIIb0066
ATP-dependent RNA helicase DDX1001515
Cyclin-dependent kinase-like 20066
Mitogen-activated protein kinase kinase kinase kinase 1001717
Serine/threonine-protein kinase Sgk30066
Atypical kinase COQ8B, mitochondrial0066
MAP/microtubule affinity-regulating kinase 4001515
Calcium/calmodulin-dependent protein kinase type 1G0088
Serine/threonine-protein kinase Nek1001717
Cyclin-dependent kinase 150066
PAS domain-containing serine/threonine-protein kinase001414
Calcium/calmodulin-dependent protein kinase kinase 2011718
EKC/KEOPS complex subunit TP53RK001616
SRSF protein kinase 10066
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase041721
Mitogen-activated protein kinase kinase kinase 5001717
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha0066
Mitogen-activated protein kinase kinase kinase 3001717
Eukaryotic translation initiation factor 2-alpha kinase 1001717
Serine/threonine-protein kinase RIO10066
MAP kinase-interacting serine/threonine-protein kinase 10369
Serine/threonine-protein kinase RIO20066
Cyclin-dependent kinase 190066
Transient receptor potential cation channel subfamily M member 60066
Testis-specific serine/threonine-protein kinase 10066
Serine/threonine-protein kinase 330066
Nucleolar GTP-binding protein 1001313
Serine/threonine-protein kinase D2001717
Serine/threonine-protein kinase DCLK30066
NUAK family SNF1-like kinase 2001616
RNA cytidine acetyltransferase001616
Serine/threonine-protein kinase SIK2011718
Myosin light chain kinase 2, skeletal/cardiac muscle0066
STE20-like serine/threonine-protein kinase 001717
Serine/threonine-protein kinase TAO3001717
Homeodomain-interacting protein kinase 20066
Tyrosine-protein kinase Srms0066
Homeodomain-interacting protein kinase 30167
dCTP pyrophosphatase 1021618
Dual specificity protein kinase CLK4011516
Serine/threonine-protein kinase Nek60167
Casein kinase I isoform gamma-1011718
Serine/threonine-protein kinase PAK 6001010
SNF-related serine/threonine-protein kinase0066
Serine/threonine-protein kinase LATS20066
Serine/threonine-protein kinase 360178
Phenylalanine--tRNA ligase beta subunit001616
BMP-2-inducible protein kinase001717
Obg-like ATPase 1001010
Midasin001616
Interleukin-1 receptor-associated kinase 4001717
Serine/threonine-protein kinase 32B0066
Mitogen-activated protein kinase kinase kinase 20001717
Cyclin-dependent kinase 12001616
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13001414
Serine/threonine-protein kinase MARK10066
Serine/threonine-protein kinase pim-2011112
Serine/threonine-protein kinase PAK 50066
Serine/threonine-protein kinase 26001717
eIF-2-alpha kinase GCN20066
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial001515
Serine/threonine-protein kinase NLK011819
Serine/threonine-protein kinase 17A0066
STE20/SPS1-related proline-alanine-rich protein kinase0066
Ephrin type-A receptor 60066
Septin-9001616
Death-associated protein kinase 20066
Ribosomal protein S6 kinase alpha-6001717
TRAF2 and NCK-interacting protein kinase011617
Serine/threonine-protein kinase tousled-like 10066
Serine/threonine-protein kinase TAO2001717
Long-chain-fatty-acid--CoA ligase 5001212
ALK tyrosine kinase receptor05712
SRSF protein kinase 30066
Serine/threonine-protein kinase ICK001515
Cyclin-dependent kinase 11A0066
Aurora kinase C0167
RAC-gamma serine/threonine-protein kinase021820
Serine/threonine-protein kinase 38-like001111
Microtubule-associated serine/threonine-protein kinase 10066
Serine/threonine-protein kinase SIK3011718
Mitogen-activated protein kinase kinase kinase 2001717
Thyroid hormone receptor-associated protein 3001212
Mitogen-activated protein kinase kinase kinase kinase 5001717
Receptor-interacting serine/threonine-protein kinase 3001616
Serine/threonine-protein kinase MRCK beta001717
Interleukin-1 receptor-associated kinase 3001717
Serine/threonine-protein kinase 24001313
Casein kinase I isoform gamma-3001717
Mitogen-activated protein kinase kinase kinase 4001717
Protein-arginine deiminase type-4015015
Progesterone receptor0261039
V-type proton ATPase subunit S10101
Vacuolar proton pump subunit B 0101
Lysine-specific demethylase 4E0404
Lysine-specific histone demethylase 1A025127
Polyunsaturated fatty acid 5-lipoxygenase010016
Cytochrome P450 11B1, mitochondrial0303
Cyclic AMP-responsive element-binding protein 10001
Sodium- and chloride-dependent GABA transporter 10606
Sodium- and chloride-dependent GABA transporter 20606
Sodium- and chloride-dependent GABA transporter 30606
Prostaglandin G/H synthase 2 011014
Linoleate 9S-lipoxygenase-40202
1-deoxy-D-xylulose 5-phosphate reductoisomerase0505
Sodium- and chloride-dependent betaine transporter0606
Prolyl endopeptidase0909
Receptor-type tyrosine-protein phosphatase S0202
Prostaglandin G/H synthase 1 012015
Polyunsaturated fatty acid lipoxygenase ALOX15B0101
Canalicular multispecific organic anion transporter 10609
Cathepsin S0101
Cathepsin D0202
Cathepsin S0617
Cathepsin K0909
Cathepsin K0404
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase0101
Nuclear factor NF-kappa-B p100 subunit 0808
Transcription factor p65012012
NACHT, LRR and PYD domains-containing protein 3 0505
Class A sortase SrtA 0303
Chain B, SARS CORONAVIRUS MAIN PROTEINASE0101
Aryl hydrocarbon receptor0123
Genome polyprotein 0314
Bcl-2-like protein 1010212
Endolysin0044
Chain A, ODORANT-BINDING PROTEIN0202
Chain A, ODORANT-BINDING PROTEIN0202
Chain B, Odorant-binding Protein0202
Chain A, ODORANT-BINDING PROTEIN0202
Chain A, ODORANT-BINDING PROTEIN0202
Chain A, ODORANT-BINDING PROTEIN0202
Chymotrypsinogen A0707
Hormone-sensitive lipase0202
Malate dehydrogenase, cytoplasmic0202
Phenol oxidase 0101
Quinone oxidoreductase0009
Proteasome subunit beta type-110304
Calpain-90101
Proteasome subunit alpha type-70304
Indoleamine 2,3-dioxygenase 109111
Calpain-2 catalytic subunit0303
Proteasome subunit beta type-10608
Proteasome subunit alpha type-10304
Proteasome subunit alpha type-20304
Proteasome subunit alpha type-30304
Proteasome subunit alpha type-40304
NF-kappa-B inhibitor alpha0011
Proteasome subunit beta type-80304
Proteasome subunit beta type-90304
Proteasome subunit alpha type-50304
Proteasome subunit beta type-40304
Proteasome subunit beta type-60304
Proteasome subunit beta type-100304
Proteasome subunit beta type-30304
Proteasome subunit beta type-20608
Proteasome subunit alpha type-60326
Proteasome subunit alpha-type 80304
Proteasome subunit beta type-70304
Gamma-secretase subunit PEN-20101
Telomerase reverse transcriptase0303
Neuraminidase0303
Neuraminidase0505
Aldo-keto reductase family 1 member C2 0808
core protein, partial0101
Sodium- and chloride-dependent GABA transporter 10202
Sodium- and chloride-dependent GABA transporter 20303
Sodium- and chloride-dependent GABA transporter 30303
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30202
Sodium- and chloride-dependent GABA transporter 20202
Eyes absent homolog 20303
Chain B, TRIOSEPHOSPHATE ISOMERASE0101
Chain B, TRIOSEPHOSPHATE ISOMERASE0101
Chain B, Triosephosphate Isomerase0101
Succinyl-diaminopimelate desuccinylase0404
Fe(3+)-Zn(2+) purple acid phosphatase0101
E3 ubiquitin-protein ligase Mdm2 isoform a0101
protein Mdm4 isoform 10101
Carboxypeptidase A10202
Thermolysin0202
Breast cancer type 1 susceptibility protein0101
BRCA1-associated RING domain protein 10101
Collagenase ColG0202
Chain A, D-MALTODEXTRIN BINDING PROTEIN0011
Chain A, Limit Dextrinase0011
Chain A, Solute-binding protein0011
Chain A, Solute-binding protein0011
Chain B, SusD0011
Chain A, SusD0011
Chain A, SusD0011
Chain A, Alpha-hemolysin0011
Chain B, Alpha-hemolysin0011
Chain C, Alpha-hemolysin0011
Chain D, Alpha-hemolysin0011
Chain E, Alpha-hemolysin0011
Chain F, Alpha-hemolysin0011
Chain G, Alpha-hemolysin0011
Chain A, Betaine ABC transporter permease and substrate binding protein0011
Chain A, Osmoprotection protein (ProX)0011
Chain A, Glycine betaine/carnitine/choline-binding protein0022
Chain A, Glycine betaine/carnitine/choline-binding protein0022
Chain A, Glycine betaine/carnitine/choline-binding protein0022
Chain A, Glycine betaine/carnitine/choline-binding protein0022
galanin receptor type 30303
Ubiquitin-like modifier activating enzyme 20202
SUMO1 activating enzyme subunit 10202
SUMO-conjugating enzyme UBC90202
DNA polymerase beta0404
DNA polymerase beta0303
Zinc finger protein GLI10303
5'-nucleotidase0202
Env polyprotein 0033
Phosphodiesterase isozyme 4 0101
Transmembrane prolyl 4-hydroxylase0134
Non-structural protein 1 0202
Glutamate receptor ionotropic, NMDA 2D07310
Glutamate receptor ionotropic, NMDA 3B07310
Peroxisome proliferator-activated receptor alpha0279
Peroxisome proliferator-activated receptor delta0033
Peroxisome proliferator-activated receptor delta07715
Peroxisome proliferator-activated receptor alpha971330
Glutamate receptor ionotropic, NMDA 2C07310
Glutamate receptor ionotropic, NMDA 3A07310
Progesterone receptor0202
Glucocorticoid receptor0528
Androgen receptor0336
Progesterone receptor0213
STAT3, partial0123
signal transducer and activator of transcription 1-alpha/beta isoform alpha0123
transcription factor p65 isoform 10022
Estrogen receptor beta0125
Pancreatic triacylglycerol lipase013014
Carbonyl reductase [NADPH] 1010012
Estrogen receptor0125
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)010010
Chain A, Avidin0011
Chain A, Protein (streptavidin)0011
Chain B, Protein (streptavidin)0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin Complex With Biotin0011
Chain D, Circularly Permuted Core-streptavidin E51/a460011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Avidin0011
Chain A, Streptavidin0011
Chain B, Streptavidin0011
Chain A, Streptavidin0011
Chain B, Streptavidin0011
nonstructural protein 10202
green fluorescent protein, partial0101
insulin-degrading enzyme isoform 10022
Receptor-type tyrosine-protein phosphatase beta0003
DNA topoisomerase 107011
CPG DNA methylase0202
Multidrug resistance protein CDR10101
Beta-1 adrenergic receptor0415
TSHR protein2002
Chain A, hepatocyte growth factor receptor0101
High affinity immunoglobulin gamma Fc receptor I0101
Rab-like protein 30099
Isoleucine--tRNA ligase, mitochondrial0077
Beta-lactamase0101
Chain H, Proteasome component PUP10101
Chain I, Proteasome component PUP30101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
26S proteasome non-ATPase regulatory subunit 110202
26S proteasome non-ATPase regulatory subunit 120202
26S proteasome non-ATPase regulatory subunit 140202
26S proteasome non-ATPase regulatory subunit 30202
Cathepsin G0404
Lysosomal protective protein0203
Chymotrypsinogen B0303
26S proteasome regulatory subunit 6A0202
Chymase0101
Proteasome subunit beta type-80101
26S proteasome regulatory subunit 70202
Lon protease homolog, mitochondrial0101
26S proteasome non-ATPase regulatory subunit 80202
26S proteasome non-ATPase regulatory subunit 70202
26S proteasome non-ATPase regulatory subunit 40202
26S proteasome complex subunit SEM10202
26S proteasome regulatory subunit 40202
26S proteasome regulatory subunit 80202
26S proteasome regulatory subunit 10B0202
26S proteasome non-ATPase regulatory subunit 20202
26S proteasome non-ATPase regulatory subunit 60202
Proteasomal ubiquitin receptor ADRM10202
ATP-dependent Clp protease proteolytic subunit0112
26S proteasome non-ATPase regulatory subunit 10202
26S proteasome non-ATPase regulatory subunit 130202
Prostaglandin E synthase0808
Genome polyprotein 08210
Angiotensin-converting enzyme 016016
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 90101
Acetylcholine receptor subunit alpha0314
Acetylcholine receptor subunit gamma0314
Acetylcholine receptor subunit beta0314
Neuronal acetylcholine receptor subunit beta-20416
Neuronal acetylcholine receptor subunit beta-40315
Neuronal acetylcholine receptor subunit alpha-30314
Neuronal acetylcholine receptor subunit alpha-70527
Neuronal acetylcholine receptor subunit alpha-40315
Acetylcholine receptor subunit delta0314
Beta-2 adrenergic receptor09111
Beta-1 adrenergic receptor09314
Beta-3 adrenergic receptor0617
Alpha-2A adrenergic receptor0303
Chain A, Nitrile Hydratase alpha subunit0101
Chain B, Nitrile Hydratase beta subunit0101
Methyl-accepting chemotaxis protein NahY0011
RNA polymerase beta subunit (EC 2.7.7.6), partial0202
90-kda heat shock protein beta HSP90 beta, partial0404
heat shock protein HSP 90-alpha isoform 20409
Lipoxygenase 0101
Neuraminidase0202
Tyrosine-protein phosphatase non-receptor type 70404
Dual specificity protein phosphatase 30404
Anthrax toxin receptor 20808
Hyaluronidase-10202
Arginase-10202
BiP isoform A0101
Nrf28008
Aldo-keto reductase family 1 member A10202
Aldo-keto reductase family 1 member C40505
Aldo-keto reductase family 1 member C10707
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0022
Chain A, glycogen phosphorylase, liver form0022
Chain A, Glycogen phosphorylase, liver form0022
Chain A, Glycogen phosphorylase, liver form0022
Chain A, Chitinase0101
atrial natriuretic peptide receptor 1 precursor210021
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A015117
Vasopressin V2 receptor0002
Adenylate cyclase type 10002
Chitotriosidase-10415
Adenosine receptor A2b0103
Palmitoleoyl-protein carboxylesterase NOTUM0336
Endochitinase B10415
Guanine deaminase0203
Chain A, Vitamin D Nuclear Receptor0011
Vitamin D3 receptor0011
Vitamin D-binding protein0011
Vitamin D3 receptor0113
Vitamin D3 receptor0033
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0415
Vitamin D3 receptor0112
Transporter0808
Vitamin D3 receptor A0022
Sodium/glucose cotransporter 107310
Sodium/glucose cotransporter 20639
Cytochrome P450 2C11 0303
Cytochrome P450 3A50629
Cytochrome P450 3A70202
Caspase-128112
N-acylethanolamine-hydrolyzing acid amidase0101
Heat sensitive channel TRPV30123
Sigma intracellular receptor 20606
Transient receptor potential cation channel subfamily M member 80224
Transient receptor potential cation channel subfamily V member 40224
G-protein coupled receptor 550135
Diacylglycerol lipase-alpha0101
Liver carboxylesterase 107012
Chain A, Beta-lactoglobulin0011
Chain A, Beta-lactoglobulin0011
UDP-3-O-acyl-N-acetylglucosamine deacetylase0011
transient receptor potential cation channel subfamily V member 17007
NADH-ubiquinone oxidoreductase chain 10101
Albumin001111
Major prion protein0066
Sodium channel protein type 1 subunit alpha1607
Sodium channel protein type 2 subunit alpha1708
Sodium channel protein type 3 subunit alpha1506
Frizzled-80011
P2X purinoceptor 40202
Oxytocin receptor0022
Lactoperoxidase0202
Cytochrome P450 2E10314
Chain A, serum paraoxonase0101
Proteasome subunit beta type-20101
Proteasome subunit beta type-10101
Glutathione S-transferase omega-10404
Solute carrier family 22 member 50001
Solute carrier family 22 member 50001
Solute carrier family 22 member 160001
Solute carrier family 22 member 210001
Solute carrier family 22 member 50001
Complement C50022
Toll-like receptor 40202
Potassium channel subfamily K member 100101
Nuclear receptor subfamily 3 group C member 3 027027
Chain A, Protein kinase CK2, alpha Subunit0101
Chain A, PROTEIN KINASE CK2, alpha SUBUNIT0101
Chain A, Protein Kinase Ck2, Alpha Subunit0101
Serine/threonine-protein kinase Sgk10303
Casein kinase II subunit alpha 0202
Casein kinase II subunit beta0202
Cyclin-A10606
Single-stranded DNA cytosine deaminase7007
Melatonin receptor type 1A0325
Melatonin receptor type 1B0325
L-ornithine N(5)-monooxygenase0112
Ubiquitin carboxyl-terminal hydrolase 20303
Ubiquitin carboxyl-terminal hydrolase isozyme L10202
Ubiquitin carboxyl-terminal hydrolase isozyme L30202
Receptor-type tyrosine-protein phosphatase epsilon0303
Tyrosine-protein phosphatase non-receptor type 60707
Tryptophan 2,3-dioxygenase0203
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN0101
Heat shock factor protein 10112
Tyrosine-protein phosphatase non-receptor type 110808
Receptor-type tyrosine-protein phosphatase eta0202
Regulator of G-protein signaling 170314
Ubiquitin carboxyl-terminal hydrolase 150101
Ubiquitin carboxyl-terminal hydrolase isozyme L50101
Monoglyceride lipase0101
Chain A, Carbonic anhydrase II0101
prostaglandin E2 receptor EP2 subtype1003
Cytochrome c oxidase subunit 10101
Cytochrome c oxidase subunit 20101
Catechol O-methyltransferase0101
Cytochrome c oxidase subunit 20505
Quinolone resistance protein NorA0405
Prostaglandin G/H synthase 10505
Cruzipain011011
Indoleamine 2,3-dioxygenase 10808
Prostaglandin G/H synthase 20809
Prostaglandin G/H synthase 10101
Cyclooxygenase-2 0202
Genome polyprotein 0505
Histamine H4 receptor08311
Caspase-20022
perilipin-5010010
perilipin-1010010
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a010010
Acetylcholinesterase0303
Tubulin beta-4A chain06412
Tubulin beta chain06412
Tubulin alpha-3C chain06412
Tumor necrosis factor receptor superfamily member 1A0101
Stromal cell-derived factor 10101
Polyunsaturated fatty acid 5-lipoxygenase0202
Tubulin alpha-1B chain06412
Tubulin alpha-4A chain06412
Tubulin beta-4B chain06412
Tubulin beta-3 chain07413
Tubulin beta-2A chain06412
Tubulin beta-8 chain06412
Tubulin alpha-3E chain06412
Tubulin alpha-1A chain06412
Sortase A0303
Tubulin alpha-1C chain06412
Tubulin beta-6 chain06412
Tubulin beta-2B chain06412
Tubulin beta-1 chain06412
Ileal sodium/bile acid cotransporter0607
Bile acid receptor0123
Gamma-aminobutyric acid receptor subunit alpha-10506
Gamma-aminobutyric acid receptor subunit beta-10506
Gamma-aminobutyric acid receptor subunit alpha-20405
Gamma-aminobutyric acid receptor subunit alpha-30405
Gamma-aminobutyric acid receptor subunit alpha-40405
Gamma-aminobutyric acid receptor subunit gamma-20405
calcineurin A1, putative0011
hepatocyte nuclear factor 4-alpha isoform 20404
ubiquitin-conjugating enzyme E2 N0606
protein AF-9 isoform a0005
melanocortin receptor 40101
CAAX prenyl protease0002
bcl-2-related protein A10606
glycogen synthase kinase-3 alpha0004
hexokinase HKDC10112
DNA repair protein RAD52 homolog isoform a0006
Solute carrier family 22 member 3015017
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase0101
Spermine oxidase0101
1,3-beta-D-glucan synthase catalytic subunit 0101
Dihydrofolate reductase 0404
DNA ligase0101
Riboflavin-binding protein0123
Histidine-rich protein PFHRP-II0304
Spike glycoprotein0213
DNA ligase 10101
Calcium-dependent protein kinase 10011
DNA ligase A0101
Phosphoethanolamine N-methyltransferase0101
Cysteine proteinase falcipain 2a 0101
Cysteine proteinase falcipain 2a 0101
NADPH oxidase 10404
Snq2p0006
Adenylate cyclase type 1 0404
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1012113
Major prion protein0011
Cys-loop ligand-gated ion channel0101
Sphingomyelin phosphodiesterase0303
Adenylate cyclase type 30404
Adenylate cyclase type 20404
Adenylate cyclase type 40404
Pleiotropic ABC efflux transporter of multiple drugs06012
Adenylate cyclase type 80404
Gastrin/cholecystokinin type B receptor0505
Aldehyde oxidase 10303
Adenylate cyclase type 60404
Adenylate cyclase type 50404
Aldehyde oxidase011012
Adenylyl cyclase 7 0404
Acetylcholinesterase 0101
Carboxylic ester hydrolase 0101
Glycine receptor subunit alpha-10088
Chain A, Acetylcholinesterase0022
Chain A, Acetylcholinesterase0022
Chain A, Acetylcholinesterase0022
Chain A, Acetylcholinesterase0022
Chain A, Acetylcholinesterase0022
Chain A, Acetylcholinesterase0022
Chain A, Acetylcholinesterase0022
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein0011
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN0011
Chain A, Choline-binding protein0011
Solute carrier family 22 member 10304
Solute carrier family 22 member 20303
Neuronal acetylcholine receptor subunit alpha-30528
Neuronal acetylcholine receptor subunit alpha-20326
Neuronal acetylcholine receptor subunit beta-30326
Neuronal acetylcholine receptor subunit beta-40528
Neuronal acetylcholine receptor subunit alpha-50326
Sodium- and chloride-dependent creatine transporter 10101
Neuronal acetylcholine receptor subunit alpha-60427
Neuronal acetylcholine receptor subunit alpha-90326
High affinity choline transporter 10101
Neuronal acetylcholine receptor subunit alpha-100326
Chain A, Glycogen phosphorylase, muscle form0101
Chain A, Glycogen phosphorylase, muscle form0101
nuclear receptor subfamily 0 group B member 10404
steroidogenic factor 10404
3-oxoacyl-acyl-carrier protein reductase 010010
Integrin beta-60101
Voltage-dependent N-type calcium channel subunit alpha-1B0415
Glutamine synthetase 0101
Potassium-transporting ATPase alpha chain 10202
Potassium-transporting ATPase subunit beta0202
Solute carrier family 22 member 8013021
Solute carrier family 22 member 1105012
Solute carrier family 22 member 40202
Solute carrier family 22 member 80709
Extracellular calcium-sensing receptor0235
shiga toxin 1 variant A subunit2002
shiga toxin 1 B subunit2002
Cell division protein FtsZ0103
DNA gyrase subunit B0101
DNA gyrase subunit A0101
DNA gyrase subunit B0102
DNA gyrase subunit A0609
DNA gyrase subunit B0609
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0102
DNA topoisomerase 4 subunit A0102
DNA gyrase subunit A0102
Multidrug resistance protein MdtK0011
DNA gyrase subunit B0506
DNA gyrase subunit A0607
Enoyl-[acyl-carrier-protein] reductase [NADH]0308
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0101
Sodium-dependent noradrenaline transporter0303
Sodium-dependent serotonin transporter0303
Sodium-dependent dopamine transporter0505
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0202
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Beta-lactamase0101
3-dehydroquinate dehydratase0011
ATP-citrate synthase 0102
Ribonuclease T0001
Cell death-related nuclease 40001
3-dehydroquinate dehydratase0011
Prolyl 4-hydroxylase0404
Alpha-ketoglutarate-dependent dioxygenase FTO0303
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10709
General amino-acid permease GAP10001
relaxin receptor 1 isoform 15005
kallikrein-5 preproprotein0101
Type IV secretion-like conjugative transfer relaxase protein TraI 0202
Macrophage metalloelastase0404
Histamine H1 receptor09110
Trypanothione reductase0101
Envelope glycoprotein0055
Beta-1 adrenergic receptor 0248
Alpha-1B adrenergic receptor 0011
Alpha-1A adrenergic receptor0415
Alpha-2B adrenergic receptor0203
Alpha-2C adrenergic receptor0203
Alpha-2A adrenergic receptor0203
Nischarin0303
Nischarin0505
Prostaglandin E2 receptor EP1 subtype0549
Prostaglandin E2 receptor EP4 subtype0516
Prostaglandin F2-alpha receptor0448
Prostaglandin E2 receptor EP3 subtype06410
Prostaglandin E2 receptor EP2 subtype0426
Prostaglandin D2 receptor0213
Beta-lactamase 0101
Solute carrier family 22 member 80305
Beta-lactamase TEM0202
5-hydroxytryptamine receptor 3A0202
Endothelin receptor type B0101
5-hydroxytryptamine receptor 2C 0404
5-hydroxytryptamine receptor 2A0303
D(2) dopamine receptor0202
D(3) dopamine receptor0202
D(2) dopamine receptor0303
5-hydroxytryptamine receptor 2B0303
5-hydroxytryptamine receptor 40325
5-hydroxytryptamine receptor 1A0303
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Fatty acid-binding protein, heart0303
Muscarinic acetylcholine receptor M20112
Lysosomal Pro-X carboxypeptidase0202
Leukotriene B4 receptor 10214
Cytochrome P450 2D10303
Cytochrome P450 2D260303
Cytochrome P450 2D30303
Kappa-type opioid receptor05210
Mu-type opioid receptor06212
Cytochrome P450 2D40303
Mas-related G-protein coupled receptor member X20055
Vesicular acetylcholine transporter0101
Tubulin polymerization-promoting protein0011
TPA: protein transporter TIM230303
Sterol 14-alpha demethylase0213
RNA-directed RNA polymerase 0112
Solute carrier family 22 member 30303
Exportin-10202
NAD-dependent histone deacetylase SIR20204
Acetylcholinesterase0808
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal0202
Sorbitol dehydrogenase0303
Zn finger protein 0101
SUMO-10202
rac GTPase-activating protein 1 isoform a0606
DNA polymerase III, partial140014
N-arachidonyl glycine receptor0213
Sodium- and chloride-dependent creatine transporter 10101
Alkaline phosphatase, germ cell type0202
G protein-coupled receptor GPR350033
G-protein coupled receptor 350022
Chain A, Breast cancer type 1 susceptibility protein6006
alkaline phosphatase, intestinal0123
toll-like receptor 90101
TPA: protein transporter TIM100606
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein0213
intestinal alkaline phosphatase precursor0213
alkaline phosphatase, germ cell type preproprotein0123
D-amino-acid oxidase0101
Phospholipase A20314
Neuronal proto-oncogene tyrosine-protein kinase Src 0102
Heme oxygenase 1 0404
Glutathione S-transferase P0303
Microtubule-associated protein tau0719
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0101
Aminopeptidase N0101
Sarcoplasmic/endoplasmic reticulum calcium ATPase 20303
Heme oxygenase 20303
Voltage-dependent L-type calcium channel subunit alpha-1D0202
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Nuclear factor erythroid 2-related factor 20159
Thioredoxin reductase 1, cytoplasmic0405
Thioredoxin reductase 30303
Sarcoplasmic/endoplasmic reticulum calcium ATPase 30303
Thioredoxin reductase 2, mitochondrial0303
Lymphocyte antigen 960011
Membrane-associated progesterone receptor component 10077
G1/S-specific cyclin-E10505
MAP kinase-activated protein kinase 30033
Dual specificity testis-specific protein kinase 20077
Multidrug resistance-associated protein 50203
RPL19A0011
transactivating tegument protein VP16 [Human herpesvirus 1]0505
COUP transcription factor 2 isoform a0101
Eukaryotic initiation factor 4A-I0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0628
Peptidyl-prolyl cis-trans isomerase FKBP30101
Peptidyl-prolyl cis-trans isomerase FKBP40101
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10415
Peptidyl-prolyl cis-trans isomerase FKBP140101
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 40101
heat shock protein 90, putative0005
Integrin alpha-40303
Smoothened homolog0224
Sonic hedgehog protein0203
Sonic hedgehog protein0426
Smoothened homolog0538
LMP1 [Human herpesvirus 4]0004
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0303
nuclear receptor coactivator 3 isoform a0303
Thymidine kinase 2, mitochondrial0101
Thymidine kinase, cytosolic07012
Thymidine kinase0203
Thymidylate synthase0406
Thymidine kinase0101
Probable deoxycytidylate deaminase0002
Cytidine deaminase0205
Enoyl-[acyl-carrier-protein] reductase [NADH] 0303
Thymidine kinase0102
Deoxynucleoside kinase0101
Deoxycytidine kinase0001
Alpha-tocopherol transfer protein0011
Coagulation factor XII0202
Serine protease hepsin0101
RAD510202
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 10101
Growth factor receptor-bound protein 20101
Pantothenate synthetase0303
Growth factor receptor-bound protein 2 0101
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase0011
Aldehyde dehydrogenase, mitochondrial0314
Chain A, Aldehyde Dehydrogenase, Mitochondrial0101
Retinal dehydrogenase 20101
Retinal dehydrogenase 10303
Aldehyde dehydrogenase X, mitochondrial0101
Aldehyde dehydrogenase family 1 member A30101
Interleukin-20022
Sodium/glucose cotransporter 20112
Sodium/myo-inositol cotransporter 20202
Solute carrier family 5 member 40202
Autoinducer 2-binding periplasmic protein LuxP0202
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase 0101
Dihydrofolate reductase0607
Tyrosine-protein kinase ABL10202
Proto-oncogene tyrosine-protein kinase Src0112
Proto-oncogene tyrosine-protein kinase LCK 0303
Myosin light chain kinase, smooth muscle0044
Potassium voltage-gated channel subfamily E member 10606
Tyrosine-protein kinase Blk0101
Potassium voltage-gated channel subfamily KQT member 10606
Tubulin alpha-1A chain0044
Myelin transcription factor 10101
Uncharacterized aarF domain-containing protein kinase 50088
Breakpoint cluster region protein0101
Protein cereblon012319
NF-kappa-B essential modulator0101
runt-related transcription factor 1 isoform AML1b7007
core-binding factor subunit beta isoform 27007
NADH-ubiquinone oxidoreductase chain 40001
Platelet-activating factor receptor3004
exodeoxyribonuclease V subunit RecD0303
exodeoxyribonuclease V subunit RecB0303
exodeoxyribonuclease V subunit RecC0303
DNA (cytosine-5)-methyltransferase 10505
Histone-lysine N-methyltransferase EHMT20505
Lysine-specific demethylase 6B0202
Lysine-specific demethylase 4A0314
Flavin reductase (NADPH)0044
Lysine-specific demethylase 6A0101
Lysine-specific demethylase 5C0101
Lysine-specific demethylase 2B0101
Deoxyhypusine hydroxylase0202
Lysine-specific demethylase 2A0101
Methylcytosine dioxygenase TET20101
Transcriptional activator Myb0101
UDP-N-acetylglucosamine 1-carboxyvinyltransferase0101
UDP-N-acetylglucosamine 1-carboxyvinyltransferase0101
Beta-glucuronidase0202
Glucose-6-phosphate 1-dehydrogenase 0101
Solute carrier organic anion transporter family member 1A50008
Solute carrier organic anion transporter family member 1A20006
ATP-binding cassette sub-family C member 110002
Solute carrier organic anion transporter family member 1A10003
Solute carrier organic anion transporter family member 1B20106
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 10606
hexokinase-4 isoform 1140014
glucokinase regulatory protein140014
Chain A, STEROID DELTA-ISOMERASE0011
Steroid Delta-isomerase0011
Thymidine kinase 2 0202
AAA family ATPase 0002
AAA family ATPase 0001
Sterol O-acyltransferase 10202
Taste receptor type 2 member 460022
metallo beta-lactamase0202
metallo-beta-lactamase IMP-10202
LANA0003
glutathione S-transferase, partial0011
B1 bradykinin receptor0101
BZLF20202
Interleukin-80202
Calcium/calmodulin-dependent protein kinase type II subunit alpha0101
C-X-C chemokine receptor type 10202
UDP-glucuronosyltransferase 1A30007
UDP-glucuronosyltransferase 1A70203
UDP-glucuronosyltransferase 1A100307
Estrogen-related receptor gamma0112
UDP-glucose 4-epimerase0202
Cysteinyl leukotriene receptor 10729
tumor necrosis factor5005
Sodium/potassium-transporting ATPase subunit alpha-1 0505
Sodium/potassium-transporting ATPase subunit beta-10505
Sodium/potassium-transporting ATPase subunit alpha-20101
Sodium/potassium-transporting ATPase subunit alpha-3 0101
Sodium/potassium-transporting ATPase subunit beta-1 0101
Sodium/potassium-transporting ATPase subunit alpha-30404
Sodium/potassium-transporting ATPase subunit beta-20404
Sodium/potassium-transporting ATPase subunit alpha-20505
Sodium/potassium-transporting ATPase subunit alpha-10101
Sodium/potassium-transporting ATPase subunit beta-30404
Sodium/potassium-transporting ATPase subunit gamma0404
Sodium/potassium-transporting ATPase subunit alpha-40404
Sodium/potassium-transporting ATPase subunit alpha-40101
Solute carrier organic anion transporter family member 4C10103
Solute carrier organic anion transporter family member 4C10002
Solute carrier organic anion transporter family member 1A40001
Cocaine esterase0607
ELAV-like protein 10303
Chain A, Sex Hormone-Binding Globulin0011
Sex hormone-binding globulin0202
Angiotensin-converting enzyme0213
Neuropeptide FF receptor 20004
Prostaglandin F2-alpha receptor0202
Prostaglandin F2-alpha receptor0011
Solute carrier family 22 member 70308
Solute carrier organic anion transporter family member 2A10101
Solute carrier family 22 member 70307
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier family 22 member 70002
Histamine N-methyltransferase0102
Calcium release-activated calcium channel protein 10101
Protein orai-20101
Protein orai-30101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta0303
3',5'-cyclic-AMP phosphodiesterase 0505
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha0303
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0303
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0909
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0303
Exopolyphosphatase PRUNE10101
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A0404
Phosphodiesterase 0303
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A0404
LacZ protein (plasmid)0112
beta-2 adrenergic receptor8019
type-1 angiotensin II receptor0101
polypyrimidine tract-binding protein 1 isoform a1001
apelin receptor0202
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase0202
Carbamate kinase0101
C-X-C chemokine receptor type 20202
C-C chemokine receptor type 50326
Gasdermin-D0101
Monoglyceride lipase0202
Gasdermin-D0101
Histone-lysine N-methyltransferase EHMT10303
hypothetical protein CAALFM_CR05890CA0003
H3 histone acetyltransferase0003
Kinesin-like protein KIF110202
Nucleotide-binding oligomerization domain-containing protein 20202
Chain A, PFV integrase0101
Chain A, PFV integrase0101
Chain A, PFV integrase0101
Integrase 0011
Vesicular acetylcholine transporter0303
Amine oxidase [flavin-containing] A 0303
Acetylcholinesterase 0606
Cholinesterase0303
Acetylcholine receptor subunit epsilon0112
Acyl-CoA:cholesterol acyltransferase 0303
Carboxylic ester hydrolase 0606
Bone morphogenetic protein 40101
Lysophosphatidylserine lipase ABHD120101
Monoacylglycerol lipase ABHD60101
3-oxo-5-alpha-steroid 4-dehydrogenase 10303
3-oxo-5-alpha-steroid 4-dehydrogenase 20303
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase0202
3-oxoacyl-[acyl-carrier-protein] synthase 3 0303
Hydroxycarboxylic acid receptor 20426
Arrestin, beta 10101
MPI protein0404
luciferase4004
hexokinase0303
hexokinase-1 isoform HKI0011
neutrophil cytosol factor 10202
phosphomannomutase 20101
fructose-bisphosphate aldolase A4004
phosphoethanolamine/phosphocholine phosphatase isoform 10202
eukaryotic translation initiation factor 4 gamma 1 isoform 40505
eukaryotic translation initiation factor 4E isoform 10505
Sulfhydryl oxidase 10101
Gamma-butyrobetaine dioxygenase0112
Insulin-degrading enzyme0202
Toxin B0101
Methionine aminopeptidase 20101
Structural capsid protein 0101
Ultraspiracle0202
20-hydroxy-ecdysone receptor 0202
Ecdysone receptor0101
Protein ultraspiracle0101
Ecdysone receptor0101
Ultraspiracle 0101
20-hydroxy-ecdysone receptor 0101
Ultraspiracle protein 0101
20-hydroxy-ecdysone receptor 0101
Beta-lactamase 0101
Beta-lactamase 0101
Chain A, POL POLYPROTEIN0101
Chain A, POL POLYPROTEIN0101
Chain B, POL POLYPROTEIN0101
Chain A, POL POLYPROTEIN0101
Chain B, POL POLYPROTEIN0101
Chain A, Pol Polyprotein0101
Chain B, Pol Polyprotein0101
Prothrombin 0303
Gag-Pol polyprotein0606
Microsomal triglyceride transfer protein large subunit0202
Envelope glycoprotein gp160 [Cleaved into: Surface protein gp120 0101
Fructose-1,6-bisphosphatase 1 0002
Reverse transcriptase 0235
Cholesterol 24-hydroxylase0224
Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta))0101
Oxoeicosanoid receptor 10101
Chain A, Casein kinase II subunit alpha0101
acetyl-CoA acetyltransferase/HMG-CoA reductase0101
unnamed protein product0101
heat shock 70kDa protein 1A0101
Aldehyde oxidase 10202
glyceraldehyde-3-phosphate dehydrogenase isoform 13003
dual specificity protein phosphatase 30101
mothers against decapentaplegic homolog 3 isoform 10101
heat shock cognate 71 kDa protein isoform 10101
Vif0404
Tat0303
dual specificity protein phosphatase 60101
heat shock cognate 71 kDa protein isoform 20101
cAMP-dependent protein kinase catalytic subunit alpha0303
Nucleophosmin0101
Glutathione S-transferase Mu 10101
G1/S-specific cyclin-D10707
Mitogen-activated protein kinase kinase kinase 80202
Squalene monooxygenase 0404
Ectonucleoside triphosphate diphosphohydrolase 10101
DNA primase0202
Tyrosine-protein kinase Lyn 0101
Polypeptide N-acetylgalactosaminyltransferase 20325
ELAV-like protein 30303
Tyrosine-protein kinase Fgr0101
Glutathione S-transferase0101
Translin-associated protein X0101
DNA polymerase iota0101
DNA polymerase eta0101
Cysteine protease ATG4B0101
M17 leucyl aminopeptidase0101
likely tRNA 2'-phosphotransferase0101
ClpP110011
D(2) dopamine receptor isoform long1001
E3 ubiquitin-protein ligase XIAP0404
Macrophage-expressed gene 1 protein0101
Histone acetyltransferase KAT2B0303
G-protein coupled receptor 840112
Chain A, PROTEIN KINASE CK2, ALPHA SUBUNIT0101
Chain A, Casein kinase II, alpha chain0101
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0011
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0011
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ0101
Protein tyrosine phosphatase type IVA 30202
Accessory gene regulator protein A0101
Genome polyprotein0101
Casein kinase II subunit alpha0101
Tissue alpha-L-fucosidase0303
Opioid receptor, delta 1b 0202
Opioid receptor homologue0202
Proenkephalin-B0011
Kappa-type opioid receptor08312
Mu-type opioid receptor0202
V-type proton ATPase subunit B, brain isoform0101
RISC-loading complex subunit TARBP20011
Capsid protein 0134
Chain A, Troponin C, slow skeletal and cardiac muscles0011
Chain A, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10011
Chain A, POLYMERASE PA0101
Chain A, Polymerase Pa0101
Chain A, Polymerase Pa0101
Chain A, Polymerase Pa0101
Chain A, Polymerase Pa0101
galactokinase4004
POsterior Segregation0088
Polycomb protein EED0123
NAD kinase0213
Polymerase acidic protein0134
Plasminogen activator inhibitor 10202
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI0404
Alpha-amylase 1A 0505
Glucose-6-phosphate 1-dehydrogenase0101
Signal transducer and activator of transcription 1-alpha/beta0011
Matrix metalloproteinase-140303
6-phosphogluconate dehydrogenase, decarboxylating0505
BH3-interacting domain death agonist0202
Bcl-2-related protein A10101
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0303
3-oxoacyl-[acyl-carrier-protein] reductase 0101
Bcl-2-like protein 20404
Bcl2-associated agonist of cell death 0404
Histone acetyltransferase KAT50101
Bcl-2-like protein 100101
Zinc finger protein mex-50089
Prolyl 4-hydroxylase, beta polypeptide0003
Motilin receptor0011
low molecular weight phosphotyrosine protein phosphatase isoform c0101
Motilin receptor0112
30S ribosomal protein S60516
30S ribosomal protein S70516
50S ribosomal protein L150516
50S ribosomal protein L100516
50S ribosomal protein L110516
50S ribosomal protein L7/L120516
50S ribosomal protein L190516
50S ribosomal protein L10516
50S ribosomal protein L200516
50S ribosomal protein L270516
50S ribosomal protein L280516
50S ribosomal protein L290516
50S ribosomal protein L310516
50S ribosomal protein L31 type B0516
50S ribosomal protein L320516
50S ribosomal protein L330516
50S ribosomal protein L340516
50S ribosomal protein L350516
50S ribosomal protein L360516
30S ribosomal protein S100516
30S ribosomal protein S110516
30S ribosomal protein S120516
30S ribosomal protein S130516
30S ribosomal protein S160516
30S ribosomal protein S180516
30S ribosomal protein S190516
30S ribosomal protein S200516
30S ribosomal protein S20516
30S ribosomal protein S30516
30S ribosomal protein S40516
30S ribosomal protein S50516
30S ribosomal protein S80516
30S ribosomal protein S90516
50S ribosomal protein L130516
50S ribosomal protein L140516
50S ribosomal protein L160516
50S ribosomal protein L230516
30S ribosomal protein S150516
50S ribosomal protein L170516
50S ribosomal protein L210516
50S ribosomal protein L300516
50S ribosomal protein L60516
30S ribosomal protein S140516
30S ribosomal protein S170516
30S ribosomal protein S10516
50S ribosomal protein L180516
Chitinase B0101
Low molecular weight phosphotyrosine protein phosphatase0404
50S ribosomal protein L20516
50S ribosomal protein L30516
50S ribosomal protein L240516
50S ribosomal protein L40516
50S ribosomal protein L220516
50S ribosomal protein L50516
30S ribosomal protein S210516
50S ribosomal protein L250516
50S ribosomal protein L36 20516
ERAP1 protein0001
ERAP2 protein0001
M17 leucyl aminopeptidase0101
M18 aspartyl aminopeptidase0303
M1-family alanyl aminopeptidase0101
leucyl-cystinyl aminopeptidase [Mus musculus]0001
Lanosterol 14-alpha demethylase0011
Olfactory receptor 51E20145
Ghrelin O-acyltransferase0202
Sodium/bile acid cotransporter0105
Solute carrier organic anion transporter family member0002
Solute carrier organic anion transporter family member 1C10404
Glutaminyl-peptide cyclotransferase0101
3-oxo-5-alpha-steroid 4-dehydrogenase 1 0505
Nuclear receptor subfamily 1 group I member 3 0101
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)0101
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)0101
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)0101
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)0101
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)0101
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)0101
Regulatory protein E20011
DNA topoisomerase 20002
Caspase-30404
DNA topoisomerase 2-alpha 0001
Luciferin 4-monooxygenase0404
Ectonucleotide pyrophosphatase/phosphodiesterase family member 20505
Vesicular glutamate transporter 30202
Trypanothione reductase0202
Amine oxidase [flavin-containing] B0303
Protein farnesyltransferase subunit beta0001
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha0001
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha0012
Protein farnesyltransferase subunit beta0012
Geranylgeranyl pyrophosphate synthase0405
Chain E, cAMP-dependent protein kinase, alpha-catalytic subunit0303
Chain I, cAMP-dependent protein kinase inhibitor, alpha form0303
Chain B, Rho-associated protein kinase 10303
Chain A, Rho-associated protein kinase 10303
Chain A, Rho-associated protein kinase 10303
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0202
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0202
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0202
Chain I, cAMP-dependent protein kinase inhibitor alpha0202
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0202
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0202
Chain I, cAMP-dependent protein kinase inhibitor alpha0202
Chain A, Rho-associated protein kinase 10303
cAMP-dependent protein kinase catalytic subunit alpha isoform Calpha10001
serine/threonine-protein kinase 33 isoform a0034
cAMP-dependent protein kinase catalytic subunit alpha 0303
C-C motif chemokine 20303
Cell division control protein 42 homolog0101
Ras-related C3 botulinum toxin substrate 10011
Rho-associated protein kinase 20202
Transcriptional activator protein LuxR0303
Fatty acid-binding protein, liver0112
Peroxisome proliferator-activated receptor alpha0011
Retinol-binding protein 40033
Prosaposin0011
Indoleamine 2,3-dioxygenase 20606
Prolyl 3-hydroxylase OGFOD10101
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 10101
3-oxo-5-alpha-steroid 4-dehydrogenase 20404
Sphingosine 1-phosphate receptor 10134
RCG53912, isoform CRA_a 0001
Sphingosine kinase 1 0001
Sphingosine kinase 20304
Sphingosine kinase 10203
Chain B, Cell division protein kinase 60101
Chain A, PROTEIN (TRANSTHYRETIN)0011
Chain B, PROTEIN (TRANSTHYRETIN)0011
Transcription factor SOX-180202
Transcriptional enhancer factor TEF-30224
Potassium channel subfamily K member 180112
Acid-sensing ion channel 50011
Chain A, Uracil Phosphoribosyltransferase0101
Skn7p0001
Dipeptidyl peptidase 40303
Potassium voltage-gated channel subfamily C member 10101
Gastrin/cholecystokinin type B receptor 0101
Potassium voltage-gated channel subfamily KQT member 30012
Potassium voltage-gated channel subfamily KQT member 20012
Serine hydroxymethyltransferase, mitochondrial0101
Potassium voltage-gated channel subfamily KQT member 40001
Potassium voltage-gated channel subfamily KQT member 50001
Acid-sensing ion channel 30202
Arylacetamide deacetylase0002
Arylacetamide deacetylase0002
Arylacetamide deacetylase0002
Chain A, Dihydrofolate reductase0011
Thymidylate synthase0606
Multidrug resistance associated protein0205
Amine oxidase [flavin-containing] A0202
Menin0011
Lecithin retinol acyltransferase0101
Protein Rev 0011
Aminoglycoside 3'-phosphotransferase 0001
Steroid hormone receptor ERR10404
Corticosteroid 11-beta-dehydrogenase isozyme 10314
Holo-[acyl-carrier-protein] synthase0101
Voltage-dependent calcium channel subunit alpha-2/delta-10202
Beta-galactosidase0101
Lipopolysaccharide heptosyltransferase 10101
PA-I galactophilic lectin0011
Jacalin0011
Protein disulfide-isomerase0101
Histone-lysine N-methyltransferase SETD70606
L-selectin0101
P-selectin0101
E-selectin0101
Thioredoxin0101
Thioredoxin, mitochondrial0101
Gamma-aminobutyric acid 0112
Gamma-aminobutyric acid receptor subunit rho-30011
Gamma-aminobutyric acid type B receptor subunit 20011
Gamma-aminobutyric acid type B receptor subunit 20101
Gamma-aminobutyric acid receptor subunit alpha-60112
Gamma-aminobutyric acid receptor subunit gamma-20112
Gamma-aminobutyric acid receptor subunit delta0112
Gamma-aminobutyric acid receptor subunit rho-10022
Gamma-aminobutyric acid receptor subunit alpha-20112
Gamma-aminobutyric acid receptor subunit alpha-30112
Gamma-aminobutyric acid receptor subunit gamma-30112
Gamma-aminobutyric acid receptor subunit rho-20011
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0202
Sodium- and chloride-dependent betaine transporter0101
Gamma-aminobutyric acid receptor subunit beta-10112
Gamma-aminobutyric acid receptor subunit alpha-10112
Gamma-aminobutyric acid receptor subunit beta-30112
4-aminobutyrate aminotransferase, mitochondrial0001
Sterol O-acyltransferase 10011
Gamma-aminobutyric acid receptor subunit alpha-50112
Gamma-aminobutyric acid receptor subunit pi0112
Gamma-aminobutyric acid receptor subunit alpha-40112
Platelet glycoprotein VI0348
Gamma-aminobutyric acid receptor subunit theta0112
Gamma-aminobutyric acid receptor subunit gamma-10112
Gamma-aminobutyric acid type B receptor subunit 10011
Gamma-aminobutyric acid type B receptor subunit 10101
Zinc finger protein GLI10202
Zinc finger protein GLI20202
epidermal growth factor receptor isoform a precursor1102
Synaptic vesicular amine transporter0404
Serine/threonine-protein kinase ULK30011
Chain A, DEOXYNUCLEOSIDE KINASE0101
Chain A, Estrogen receptor 1 (alpha)0101
Chain A, Transthyretin0011
Chain A, Transthyretin0011
Steroid hormone receptor ERR20101
Ornithine decarboxylase0202
Solute carrier family 2, facilitated glucose transporter member 40101
Cystic fibrosis transmembrane conductance regulator0011
DNA (cytosine-5)-methyltransferase 3-like0202
DNA (cytosine-5)-methyltransferase 3A0303
Glucagon-like peptide 1 receptor0011
Glucagon-like peptide 1 receptor0336
Glucagon receptor0011
Glucagon receptor0011
Asialoglycoprotein receptor 10112
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
Metabotropic glutamate receptor 80202
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Glutamate receptor ionotropic, kainate 10528
Metabotropic glutamate receptor 10314
Metabotropic glutamate receptor 20112
Metabotropic glutamate receptor 30213
Metabotropic glutamate receptor 40213
Metabotropic glutamate receptor 50325
Metabotropic glutamate receptor 60112
Metabotropic glutamate receptor 70112
Glutamate receptor ionotropic, kainate 10325
Metabotropic glutamate receptor 50124
Glutamate receptor ionotropic, kainate 20539
Glutamate receptor 10325
Glutamate receptor 20325
Glutamate receptor 30123
Glutamate receptor ionotropic, kainate 30506
Metabotropic glutamate receptor 80011
Glutamate receptor 40314
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80213
Glutamate receptor ionotropic, kainate 40506
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, kainate 20325
Glutamate receptor ionotropic, kainate 30303
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, kainate 50303
Glutamate receptor ionotropic, kainate 50506
Glutamate racemase0001
Protein-glutamine gamma-glutamyltransferase 20202
Chain A, Glutamine Binding Protein0011
Neutral amino acid transporter A0404
Asc-type amino acid transporter 10202
Neutral amino acid transporter B(0)0404
Amino acid transporter0404
Chain A, Protein (aspartate Aminotransferase)0011
Chain A, Aspartate Aminotransferase0011
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E0011
Sodium- and chloride-dependent glycine transporter 10202
Large neutral amino acids transporter small subunit 1010011
Serine racemase0101
Sodium- and chloride-dependent glycine transporter 20101
High mobility group protein B10033
High mobility group protein B10001
Corticosteroid 11-beta-dehydrogenase isozyme 20112
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase0101
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase0101
Glutamine synthetase 0101
Cytochrome P450 71B10102
Glutamine synthetase 0101
2-dehydro-3-deoxyphosphooctonate aldolase0101
Estrogen receptor 10202
4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase1001
Malate dehydrogenase, mitochondrial0101
L-lactate dehydrogenase B chain0101
Malate dehydrogenase, cytoplasmic0101
L-lactate dehydrogenase B chain0101
DNA-3-methyladenine glycosylase0202
Type 1 InsP3 receptor isoform S2 2002
L-lactate dehydrogenase0101
Aspartyl/asparaginyl beta-hydroxylase0202
L-lactate dehydrogenase0101
L-lactate dehydrogenase B chain0101
L-lactate dehydrogenase0101
Inosine-5'-monophosphate dehydrogenase 0101
Chain A, Bromodomain-containing Protein 40011
Chain A, BROMODOMAIN-CONTAINING PROTEIN 20101
Chain A, BROMODOMAIN-CONTAINING PROTEIN 20101
Bromodomain testis-specific protein0101
ATPase family AAA domain-containing protein 20011
Lysine-specific histone demethylase 1B0101
guanine nucleotide-binding protein subunit alpha-150112
trace amine-associated receptor 10112
Ricin0101
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase0022
Purine nucleoside phosphorylase 0012
Chain A, Hypoxanthine Phosphoribosyltransferase0101
Chain A, HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE0101
Chain A, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE0011
Chain B, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE0011
Chain A, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE0011
Chain A, Xanthine phosphoribosyltransferase0011
Histidine triad nucleotide-binding protein 10011
Chain A, Uracil Phosphoribosyltransferase0011
Chain B, Uracil Phosphoribosyltransferase0011
Chain C, Uracil Phosphoribosyltransferase0011
Ras-related protein Rab-7a0011
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 90202
Free fatty acid receptor 10011
Cyclin-dependent kinase 100033
Vitamin D-binding protein0101
HLA class I histocompatibility antigen, A alpha chain 0033
5-hydroxytryptamine receptor 2A0101
AP-2 complex subunit sigma0101
N-acetyltransferase Eis0202
Calcitonin gene-related peptide type 1 receptor0101
Zinc finger protein 6640101
Chain A, Dual specificity tyrosine-phosphorylation-regulated kinase 1A0101
Glycogen synthase kinase-3 beta 0202
CDC-like kinase 1, isoform CRA_c0001
[Tau protein] kinase 0202
dual specificity protein kinase CLK41001
Dual specificity protein kinase CLK20101
Dual specificity protein kinase CLK30101
Dual specificity protein kinase CLK40101
Dual specificity tyrosine-phosphorylation-regulated kinase 30101
Cyclin-T10505
Protein kinase C gamma type0303
Dual specificity protein kinase CLK10101
Sodium-dependent dopamine transporter0101
Neuromedin-B receptor0101
Cyclin-H0303
Mitogen-activated protein kinase 10202
Serine/threonine-protein kinase haspin0101
Dual specificity tyrosine-phosphorylation-regulated kinase 40101
Chain E, Fibrin beta chain0303
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)0001
CDK50001
major prion protein preproprotein Prp precursor0101
endoribonuclease toxin MazF0011
Aurora kinase B-A0101
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 10303
Heparanase0022
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Protein (female-specific Histamine Binding Protein 2)0011
aryl hydrocarbon receptor nuclear translocator0001
transforming acidic coiled-coil-containing protein 30001
Histamine H3 receptor0202
Histamine N-methyltransferase 0101
Glutaminyl-peptide cyclotransferase0202
Equilibrative nucleoside transporter 40001
Histamine H4 receptor0123
Histamine H4 receptor0123
Histamine H4 receptor 0101
Chain A, HISTIDINE-BINDING PROTEIN0011
Histidine-binding periplasmic protein0011
Intestinal-type alkaline phosphatase0606
Phospholipase A-2-activating protein0606
Phosphatidylcholine-sterol acyltransferase0011
G-protein coupled receptor 10011
N-glycosylase/DNA lyase0202
Aspartate aminotransferase, cytoplasmic0101
Cyclic GMP-AMP synthase0101
Toll-like receptor 90101
Toll-like receptor 70101
Uracil nucleotide/cysteinyl leukotriene receptor0404
Glutamine synthetase0101
Ribonucleoside-diphosphate reductase large subunit0101
2-5A-dependent ribonuclease0203
Caspase-40303
Caspase-50303
Dehydrogenase/reductase SDR family member 90101
Prostacyclin receptor0112
Tyrosine-protein kinase JAK2 0011
Chain A, Cell Division Protein Kinase 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, Cell Division Protein Kinase 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, Cell Division Protein Kinase 20101
Chain A, PROTEIN (PROTEASE)0101
Chain B, PROTEIN (PROTEASE)0101
Chain A, PROTEIN (PROTEASE)0101
Chain B, PROTEIN (PROTEASE)0101
Chain A, HIV-1 PROTEASE0101
Chain B, HIV-1 PROTEASE0101
Chain A, HIV-II PROTEASE0101
Chain B, HIV-II PROTEASE0101
Chain A, POL polyprotein0011
Chain B, POL polyprotein0011
Chain A, POL polyprotein0011
Chain B, POL polyprotein0011
Chain A, POL polyprotein0011
Chain B, POL polyprotein0011
Chain A, POL polyprotein0011
Chain B, POL polyprotein0011
Chain A, protease RETROPEPSIN0101
Chain B, protease RETROPEPSIN0101
Chain A, protease RETROPEPSIN0101
Chain B, protease RETROPEPSIN0101
Chain A, protease RETROPEPSIN0101
Chain B, protease RETROPEPSIN0101
Chain A, POL polyprotein0202
Chain B, POL polyprotein0202
Chain A, POL polyprotein0202
Chain B, POL polyprotein0202
Chain A, HIV-1 protease0101
Chain B, HIV-1 protease0101
Chain A, Pol polyprotein0101
Chain B, Pol polyprotein0101
Chain A, Pol polyprotein0101
Chain B, Pol polyprotein0101
Chain A, Pol polyprotein0101
Chain B, Pol polyprotein0101
Chain A, Pol polyprotein0101
Chain B, Pol polyprotein0101
Chain A, Hiv-1 Protease0101
Chain B, Hiv-1 Protease0101
Chain A, Hiv-1 Protease0101
Chain B, Hiv-1 Protease0101
Chain A, Hiv-1 Protease0101
Chain B, Hiv-1 Protease0101
Gag-Pol polyprotein0404
Gag-Pol polyprotein0202
Gag polyprotein0101
Gag-Pol polyprotein0303
Gag-Pol polyprotein0303
Thromboxane-A synthase0103
Protease 0101
Chain A, Glycogen Synthase Kinase-3 Beta0101
Chain B, Glycogen Synthase Kinase-3 Beta0101
Chain A, Glycogen Synthase Kinase-3 Beta0101
Chain A, membrane-associated prostaglandin E synthase-20101
Phospholipase A2, major isoenzyme0202
C-X-C chemokine receptor type 30303
Prostaglandin D2 receptor 0202
Dehydrogenase/reductase SDR family member 90101
Prostaglandin D2 receptor 20213
Chain B, Pulmonary surfactant-associated protein D0101
Chain A, Pulmonary surfactant-associated protein D0101
Chain A, BETA-SPECTRIN0011
Chain A, Phospholipase C Delta-10011
Chain A, Inositol 1,4,5-trisphosphate receptor type 10011
Inositol-trisphosphate 3-kinase A0101
Inositol 1,4,5-trisphosphate receptor type 1 0022
Inositol 1,4,5-trisphosphate receptor type 20101
Inositol 1,4,5-trisphosphate receptor type 30112
Inositol polyphosphate-5-phosphatase A0101
Inositol 1,4,5-trisphosphate receptor type 10112
G-protein coupled bile acid receptor 10022
SUMO-1-specific protease0101
SUMO1/sentrin specific peptidase 70101
caspase-3 isoform a preproprotein0202
sentrin-specific protease 80101
Dihydroorotate dehydrogenase (quinone), mitochondrial0505
Formamidopyrimidine-DNA glycosylase0101
Endonuclease III-like protein 10101
Isocitrate lyase0101
Putative FAD-containing monooxygenase MymA0101
Dihydrofolate reductase0303
Endonuclease 8-like 10101
Butyrophilin subfamily 3 member A10236
Beta-2 adrenergic receptor0011
Beta-3 adrenergic receptor0011
Beta-2 adrenergic receptor0202
Taste receptor type 2 member 380036
Taste receptor type 2 member 390011
Taste receptor type 2 member 400011
Taste receptor type 2 member 410011
Taste receptor type 2 member 430011
Taste receptor type 2 member 310022
Taste receptor type 2 member 450011
Taste receptor type 2 member 300011
Taste receptor type 2 member 190011
Taste receptor type 2 member 200011
Taste receptor type 2 member 500011
Taste receptor type 2 member 600022
Taste receptor type 2 member 420011
Taste receptor type 2 member 140023
Taste receptor type 2 member 130022
Taste receptor type 2 member 100011
Taste receptor type 2 member 90022
Taste receptor type 2 member 80011
Taste receptor type 2 member 70011
Taste receptor type 2 member 50011
Taste receptor type 2 member 40022
Taste receptor type 2 member 30011
Taste receptor type 2 member 10011
Ornithine decarboxylase0002
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 20011
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 10011
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 40011
Protein E60404
Chain A, Glutamate receptor 20011
Chain A, Glutamate receptor 20011
Chain C, Glutamate receptor 20011
Glutamate receptor ionotropic, kainate 40101
3-oxoacyl-[acyl-carrier-protein] synthase 30101
Gap junction alpha-1 protein0101
Gap junction beta-2 protein0101
Acyl-protein thioesterase 10101
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0202
Epoxide hydrolase 1 0202
Cytochrome P450 1440022
Steroid C26-monooxygenase0022
Steroid C26-monooxygenase0022
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0202
Cytochrome P450 26A10101
Camphor 5-monooxygenase0001
Epoxide hydrolase 10001
Cholesterol side-chain cleavage enzyme, mitochondrial 0101
Cytochrome P450 2A20101
Cytochrome P450 11B1, mitochondrial 0303
Cytochrome P450 7A1 0101
Gonadotropin-releasing hormone receptor0314
Cytochrome P450 4F20202
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0101
Cytochrome P450 7A10101
Lanosterol 14-alpha demethylase 0202
Substance-P receptor0527
Chain A, Lectin0011
Chain A, Lectin0011
Chain A, Lectin0011
Chain A, Lectin0011
Chain A, ERYTHRINA CRISTA-GALLI LECTIN0011
Chain A, ERYTHRINA CRISTA-GALLI LECTIN0011
Chain A, cellulase0011
Chain A, cellulase0011
Chain A, Galectin-30011
Chain A, Anti-tumor lectin0101
Galectin-30101
Galectin-90011
Galectin-80011
Beta-galactoside-binding lectin0101
Galectin-10113
Galectin-30112
Galectin-30113
Galectin-70011
Alpha 1,4 galactosyltransferase0001
WD repeat-containing protein 50303
Histone-lysine N-methyltransferase 2A0303
Cytosolic endo-beta-N-acetylglucosaminidase0202
matrix metalloproteinase 1, partial0011
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Cereblon isoform 40303
DNA-binding protein Ikaros0014
DNA damage-binding protein 10213
Zinc finger protein Aiolos0011
Chain A, AMINOPEPTIDASE0202
Chain A, AMINOPEPTIDASE0202
Chain A, Leucine Aminopeptidase0101
Cysteinyl leukotriene receptor 20213
Gonadotropin-releasing hormone receptor0101
Alkaline phosphatase, placental type0101
Alkaline phosphatase, tissue-nonspecific isozyme 0303
Intestinal-type alkaline phosphatase0202
Synaptic vesicle glycoprotein 2A0202
SLC16A10 protein0004
Monocarboxylate transporter 100004
CAAX prenyl protease 2 isoform 20001
Potassium voltage-gated channel subfamily D member 20202
Dipeptidyl peptidase 90101
Dipeptidyl peptidase IV0101
POU domain, class 2, transcription factor 20101
POU domain, class 2, transcription factor 10102
Prolyl endopeptidase FAP0101
Prolyl endopeptidase FAP0101
Dipeptidyl peptidase 80202
Dipeptidyl peptidase 90101
Dipeptidyl peptidase 20101
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial0101
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0101
Renin0101
Sterol O-acyltransferase 10404
N-formyl peptide receptor 20101
inositol monophosphatase 12002
Ephrin type-A receptor 20101
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D0101
Chain A, protease0101
Chain B, protease0101
Chain A, protease0011
Chain B, protease0011
Chain A, protease0011
Chain B, protease0011
Chain A, protease0011
Chain B, protease0011
Chain A, protease0011
Chain B, protease0011
Chain A, protease0011
Chain B, protease0011
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, PROTEASE RETROPEPSIN0101
Chain B, PROTEASE RETROPEPSIN0101
Chain A, Protease Retropepsin0101
Chain B, Protease Retropepsin0101
Chain A, Protease Retropepsin0101
Chain B, Protease Retropepsin0101
Gag-Pol polyprotein0202
CAAX prenyl protease 1 homolog0101
Plasmepsin V 0202
Translocator protein0101
Neprilysin0101
Type-1 angiotensin II receptor0213
Chain A, Antigen Cd11a (p180)0101
Integrin beta-20101
Intercellular adhesion molecule 10101
Integrin alpha-L0112
Tryptophan 5-hydroxylase 10101
Queuine tRNA-ribosyltransferase0101
histidine kinase 0101
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 70003
Chemotaxis protein CheA0101
Cytosol aminopeptidase0202
Collagenase 30606
DNA topoisomerase 10101
Melatonin receptor type 1C0112
Transcription factor HES-10101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Lysophosphatidic acid receptor 60011
Lysophosphatidic acid receptor 4 0011
Lysophosphatidic acid receptor 10022
Lysophosphatidic acid receptor 40011
Lysophosphatidic acid receptor 50011
Lysophosphatidic acid receptor 20011
Lysophosphatidic acid receptor 30011
Interleukin-6 receptor subunit beta0011
Chain A, Retinoic acid receptor RXR-alpha0011
Chain A, Peroxisome proliferator-activated receptor gamma0011
[tau protein] kinase 0101
C-C chemokine receptor type 60202
C-C chemokine receptor type 50101
C-C chemokine receptor type 50101
bioA0001
Cytochrome P450 1A2 0103
Nociceptin receptor0101
Melatonin receptor type 1A0112
Melatonin receptor type 1C0112
Melatonin receptor type 1B0112
Large neutral amino acids transporter small subunit 1 0202
Vitamin K-dependent gamma-carboxylase 0001
Secreted chorismate mutase0202
Transient receptor potential cation channel subfamily M member 80225
UDP-glucose 6-dehydrogenase0101
UDP-glucose 6-dehydrogenase0101
UDP-glucuronosyltransferase 1A1 0101
microphthalmia-associated transcription factor isoform 90303
Tumor necrosis factor0314
Cystathionine gamma-lyase0303
Cystine/glutamate transporter0202
Hydroxyacid oxidase 10101
Multidrug transporter MdfA0303
Aldehyde oxidase 1 0404
Trace amine-associated receptor 10011
Trace amine-associated receptor 10022
Dopamine beta-hydroxylase 0202
Chain A, Methionyl-tRNA synthetase0011
Chain A, Methionyl-tRNA synthetase0011
Chain A, Aminopeptidase0101
Chain A, Methionine aminopeptidase0101
S-ribosylhomocysteine lyase0101
Adenylate cyclase type 50001
S-adenosylmethionine synthase isoform type-10001
S-adenosylmethionine synthase isoform type-20001
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Thymidylate synthase 0101
Thymidylate synthase 0101
ATP-binding cassette sub-family C member 30103
Dihydrofolate reductase0303
Dihydrofolate reductase0101
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0303
Dihydrofolate reductase0303
Thymidylate synthase0303
Bifunctional dihydrofolate reductase-thymidylate synthase0303
Folate receptor beta0101
Folate receptor alpha0101
Histidine decarboxylase0123
Trifunctional purine biosynthetic protein adenosine-30101
Bifunctional purine biosynthesis protein ATIC0303
Reduced folate transporter0202
Pteridine reductase 10202
Bifunctional dihydrofolate reductase-thymidylate synthase0203
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Trifunctional purine biosynthetic protein adenosine-30101
Dihydrofolate reductase 0303
Dihydrofolate reductase0203
Proton-coupled folate transporter0101
Cytochrome P450 2A130437
TCRAV4S1, partial0101
albumin precursor0101
Catechol O-methyltransferase0001
T cell receptor, partial1001
luteinizing hormone receptor1001
Apoptotic peptidase activating factor 10101
caspase-9 isoform alpha precursor0101
Glutathione reductase0102
Dihydrolipoyl dehydrogenase, mitochondrial0104
Dihydrolipoyl dehydrogenase 0102
Acidic phospholipase A2 20101
Serine racemase0101
Nuclear receptor subfamily 1 group I member 20011
Chain A, androgen receptor0011
Chain A, androgen receptor0011
Thioredoxin reductase 0101
Flavodoxin0001
Potassium channel subfamily K member 90101
Chain A, PROGESTERONE RECEPTOR0101
Glucocorticoid receptor 0101
Tegument protein VP160011
Glucocorticoid receptor0112
Glucocorticoid receptor0101
Sucrase-isomaltase 0101
Ceramide glucosyltransferase0101
Beta-galactosidase0101
Lysosomal alpha-glucosidase0101
Non-lysosomal glucosylceramidase0101
Chain A, Probable serine/threonine-protein kinase pknB0101
phospholipase A2, group III0202
histone-lysine N-methyltransferase NSD2 isoform 10001
NEDD8-activating enzyme E1 regulatory subunit0011
NEDD8-activating enzyme E1 catalytic subunit0011
Nuclear receptor corepressor 10101
Leukotriene C4 synthase0101
Cysteinyl leukotriene receptor 10101
estrogen receptor beta isoform 10303
Islet amyloid polypeptide0101
Low molecular weight phosphotyrosine protein phosphatase0101
C-terminal-binding protein 12002
Solute carrier family 22 member 120101
Solute carrier family 22 member 120404
Acyl-CoA desaturase 10202
Nociceptin receptor0101
Mu-type opioid receptor0101
Phosphotyrosine protein phosphatase 0202
Low molecular weight protein-tyrosine phosphatase A0101
Tyrosine-protein phosphatase non-receptor type 120101
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Tyrosine-protein phosphatase non-receptor type 220101
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
Inosine-5'-monophosphate dehydrogenase0102
UDP-glucuronosyltransferase 1A80004
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-10101
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-10101
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-10101
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-10101
Chain A, Pancreatic alpha-amylase0101
Chain A, Pancreatic alpha-amylase0101
DNA dC->dU-editing enzyme APOBEC-3A isoform a0101
Tyrosine-protein kinase transforming protein Fps0101
Solute carrier family 2, facilitated glucose transporter member 20202
Solute carrier family 2, facilitated glucose transporter member 4 0202
DNA primase TraC0101
DNA-(apurinic or apyrimidinic site) endonuclease0101
Cystathionine beta-synthase0101
Aldo-keto reductase family 1 member C210303
RNA-editing ligase 1, mitochondrial0101
Sialidase-40101
Sialidase-10101
Sialidase-30101
Sepiapterin reductase0101
Phenylethanolamine N-methyltransferase0202
Chain A, Protein tyrosine kinase 2 beta0101
Chain A, Protein tyrosine kinase 2 beta0101
Chain A, Protein tyrosine kinase 2 beta0101
vasopressin V1b receptor2002
relaxin receptor 2 isoform 11001
Bromodomain adjacent to zinc finger domain protein 2B0101
Muscarinic acetylcholine receptor 0011
Muscarinic acetylcholine receptor 0101
Chain A, PROTEIN (5-AMINOLAEVULINIC ACID DEHYDRATASE)0101
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10002
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10001
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Chain A, Cholix toxin0101
Beta-hexosaminidase subunit alpha0101
Chain A, Hth-type Transcriptional Regulator Ttgr0022
Chain A, Hth-type Transcriptional Regulator Ttgr0022
Chain A, Mitogen-activated protein kinase 140101
Chain A, Mitogen-activated protein kinase 140101
Chain A, Mitogen-activated protein kinase 140101
Chain A, Mitogen-activated protein kinase 140101
Chain A, Mitogen-activated protein kinase 140101
Chain A, Mitogen-activated protein kinase 140101
Chain A, Mitogen-activated protein kinase 140101
Chain A, Mitogen-activated protein kinase 140101
Chain A, Mitogen-activated protein kinase 140101
G protein-activated inward rectifier potassium channel 20011
G protein-activated inward rectifier potassium channel 40011
G protein-activated inward rectifier potassium channel 10011
Geranylgeranyl transferase type-2 subunit alpha0001
Neuropeptide Y receptor type 10202
Neuropeptide Y receptor type 20202
Chain B, Hiv-1 Reverse Transcriptase0101
Chain A, Hiv-1 Reverse Transcriptase0101
Chain A, Hiv-1 Reverse Transcriptase0101
Chain A, Hiv-1 Reverse Transcriptase0101
Chain B, Hiv-1 Reverse Transcriptase0101
Chain A, Reverse transcriptase/ribonuclease H0101
Gag-Pol polyprotein0101
Imidazoleglycerol-phosphate dehydratase0101
Ryanodine receptor 10101
Exoribonuclease H 0202
Cardiac ryanodine receptor 2 0101
Cholesteryl ester transfer protein0314
D-amino-acid oxidase0101
Hydroxycarboxylic acid receptor 30011
Nicotinamidase0101
Hydroxycarboxylic acid receptor 20011
D-aspartate oxidase0101
Hydroxycarboxylic acid receptor 20112
Chain A, NAD-dependent deacetylase0101
Poly [ADP-ribose] polymerase 20101
NAD-dependent protein deacetylase HST20101
NAD(+) hydrolase SARM10101
NAD-dependent protein deacetylase sirtuin-60202
NAD-dependent protein deacetylase 0101
Glutamate dehydrogenase 1, mitochondrial 0101
Neuronal acetylcholine receptor subunit alpha-40213
Acetylcholine receptor subunit alpha0213
Acetylcholine receptor subunit beta0213
Acetylcholine receptor subunit gamma0213
Acetylcholine receptor subunit delta0213
Neuronal acetylcholine receptor subunit alpha-40101
Acetylcholine receptor subunit beta-like 20202
Neuronal acetylcholine receptor subunit alpha-50011
Neuronal acetylcholine receptor subunit alpha-70202
Acetylcholine-binding protein0112
Neuronal acetylcholine receptor subunit beta-30112
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit alpha-60112
Neuronal acetylcholine receptor subunit alpha-50202
Liver carboxylesterase B-10101
Neuronal acetylcholine receptor subunit beta-30202
Neuronal acetylcholine receptor subunit beta-40202
Neuronal acetylcholine receptor subunit alpha-30202
Soluble acetylcholine receptor0101
Neuronal acetylcholine receptor subunit alpha-20202
Neuronal acetylcholine receptor subunit beta-20213
Neuronal acetylcholine receptor subunit alpha-60202
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Chain A, Phospholipase A2 isoform 30011
4-hydroxyphenylpyruvate dioxygenase0101
4-hydroxyphenylpyruvate dioxygenase 0101
4-hydroxyphenylpyruvate dioxygenase0101
Sodium/iodide cotransporter0101
Extracellular calcium-sensing receptor0011
Extracellular calcium-sensing receptor0202
Casein kinase I isoform alpha0101
Glycogen synthase kinase 3 0101
Dual specificity protein phosphatase 50101
Cathepsin L20202
Pro-cathepsin H0101
Dipeptidyl peptidase 10101
Cathepsin Z0101
Cathepsin F0101
STE240001
Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]0011
Receptor-type tyrosine-protein phosphatase C0101
Receptor-type tyrosine-protein phosphatase F0303
Receptor-type tyrosine-protein phosphatase alpha0202
M-phase inducer phosphatase 20404
Chain A, Adipocyte Lipid-binding Protein0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
putative potassium channel subunit0011
Nuclear factor erythroid 2-related factor 20002
Nitric oxide synthase, brain0101
Bifunctional cytochrome P450/NADPH--P450 reductase0011
Potassium-transporting ATPase subunit beta0101
Potassium-transporting ATPase alpha chain 10101
Bombesin receptor subtype-30011
Potassium-transporting ATPase alpha chain 20001
Chain A, ARGINASE 10101
Chain A, Arginase 10101
Chain A, ARGINASE 10101
Chain A, L-ARGININE\\:GLYCINE AMIDINOTRANSFERASE0101
Solute carrier family 2, facilitated glucose transporter member 90224
MecA 0101
Chain A, Pyruvate kinase, M2 isozyme0101
Chain A, Phosphonopyruvate hydrolase0101
Chain A, Phosphoenolpyruvate-protein phosphotransferase0101
polyadenylate-binding protein 10101
MBT domain-containing protein 10101
Lethal(3)malignant brain tumor-like protein 40101
Lethal(3)malignant brain tumor-like protein 30101
Lethal(3)malignant brain tumor-like protein 10101
chaperonin GroEL2002
Alpha-1B adrenergic receptor0202
Alpha-2A adrenergic receptor0101
Microphthalmia-associated transcription factor0001
Cholecystokinin receptor type A0639
Beta-tubulin 0101
Chain B, Cell division protein kinase 60101
Chain B, Cell division protein kinase 60101
Cyclin-K0101
G1/S-specific cyclin-D20101
G1/S-specific cyclin-D30202
CDK-activating kinase assembly factor MAT10101
Genome polyprotein0101
Chain A, Fatty acid-binding protein, adipocyte0101
Toll-like receptor 20101
Testosterone 17-beta-dehydrogenase 30101
Putative nucleoside diphosphate kinase0022
Nucleoside diphosphate kinase B0033
Nuclear receptor subfamily 4 group A member 30101
Peroxiredoxin-like 2A0101
Dual specificity mitogen-activated protein kinase kinase 2 0101
Dual specificity mitogen-activated protein kinase kinase 1 0101
Gastrin/cholecystokinin type B receptor0437
Aldehyde oxidase 10303
Aldehyde oxidase 10303
Macrophage colony-stimulating factor 1 receptor0101
Chain A, Focal adhesion kinase 10101
B-cell lymphoma 6 protein0011
Chain A, Immunoglobulin0011
Chain B, Immunoglobulin0011
Muscarinic acetylcholine receptor M50113
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Ferritin light chain0022
Chain A, Ferritin light chain0022
Chain A, Ferritin light chain0022
Chain A, Ferritin light chain0022
Chain A, Ferritin light chain0022
Chain A, Ferritin light chain0022
Chain A, Ferritin light chain0022
electroneutral potassium-chloride cotransporter KCC20011
G-protein coupled receptor 550101
Thymidylate synthase0101
Alpha-1A adrenergic receptor0011
fMet-Leu-Phe receptor0202
Beta-lactamase0303
Monocarboxylate transporter 10202
Sodium/hydrogen exchanger 9B20101
Sodium/glucose cotransporter 1 0101
Chain D, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)0101
Chain A, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)0101
Chain A, Beta-arrestin 10011
Beta-lactamase 0101
Muscarinic acetylcholine receptor DM10202
XBP10101
DNA damage-inducible transcript 3 protein0101
Ubiquitin carboxyl-terminal hydrolase 10202
WD repeat-containing protein 480202
CDGSH iron-sulfur domain-containing protein 10202
Peroxisome proliferator-activated receptor gamma0101
Carnitine O-palmitoyltransferase 2, mitochondrial0202
CDGSH iron-sulfur domain-containing protein 20202
C-X-C chemokine receptor type 40101
Atypical chemokine receptor 30011
C-X-C chemokine receptor type 40204
dual specificity mitogen-activated protein kinase kinase 11001
RAF proto-oncogene serine/threonine-protein kinase isoform b1001
M-phase inducer phosphatase 10303
Platelet-activating factor acetylhydrolase0204
Mitogen-activated protein kinase kinase kinase 140101
Sodium/potassium/calcium exchanger 40112
Sodium/potassium/calcium exchanger 20112
luciferase0001
Glutamine synthetase0011
Nociceptin receptor0011
Pannexin-10101
Pannexin-10101
Vascular cell adhesion protein 10101
Glutamate 5-kinase0001
Chloroquine resistance transporter0202
Free fatty acid receptor 20011
Neuromedin-K receptor0011
Nuclear receptor subfamily 2 group E member 10033
NADH-cytochrome b5 reductase 3 0101
Thyroid peroxidase0101
Chain A, Protocatechuate 3,4-dioxygenase alpha chain0011
Chain B, Protocatechuate 3,4-dioxygenase beta chain0011
cathepsin L10202
3-dehydroquinate synthase0101
Coproheme decarboxylase0011
Interleukin-50202
Interleukin-50101
Interleukin-5 receptor subunit alpha0202
Lysine-specific demethylase 4C0303
Trans-sialidase0101
Trans-sialidase0101
Chain A, dATP pyrophosphohydrolase0101
Chain A, Adenylate cyclase type 50101
Chain B, Adenylate cyclase type 20101
Chain A, APH(2')-Id0101
glucose-6-phosphate dehydrogenase0101
B2 bradykinin receptor0101
Chymotrypsin-like elastase family member 10101
Heterogeneous nuclear ribonucleoprotein A10011
Malate dehydrogenase0202
Glutathione reductase0101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10202
Aldo-keto reductase family 1 member B10101
cGMP-dependent 3',5'-cyclic phosphodiesterase0303
Chymotrypsin-C0101
Multidrug resistance protein 1a0001
Histone deacetylase 80112
NAD-dependent protein deacetylase sirtuin-70101
Phospholipase D20101
Phospholipase D1 0202
Phospholipase D10213
Gastric inhibitory polypeptide receptor0101
Cathepsin K0101
Chain A, TGF-beta receptor type I0101
Chromaffin granule amine transporter0101
Synaptic vesicular amine transporter0213
Synaptic vesicular amine transporter0101
Chain A, Troponin C, slow skeletal and cardiac muscles0011
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Aryl hydrocarbon receptor0101
Myc proto-oncogene protein0102
DNA polymerase alpha catalytic subunit0101
N1L 0101
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
Beta-lactoglobulin0011
MSRA protein0101
plectin 10101
tyrosine-protein phosphatase non-receptor type 7 isoform 20202
Ribonuclease HI0202
NS5 0011
Polymerase basic protein 20011
RNA-directed RNA polymerase catalytic subunit0011
Adenosine receptor A10101
Genome polyprotein0011
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain H, Immunoglobulin Igg1 Heavy chain0011
Chain L, Immunoglobulin Igg1 Lambda Light Chain0011
Chain A, DODECIN0011
Chain A, DODECIN0011
Chain C, DODECIN0011
Chain E, DODECIN0011
Reverse transcriptase 0101
4-hydroxy-3-methylbut-2-enyl diphosphate reductase0101
Farnesyl diphosphate synthase0101
H0202
Phosphotransferase 0101
Farnesyl diphosphate synthase0101
Chain A, HIV-1 PROTEASE0101
Chain B, HIV-1 PROTEASE0101
Chain A, Endothiapepsin0101
Chain A, Endothiapepsin0101
Chain A, Activated Factor Xa Heavy Chain0101
Suppressor of tumorigenicity 14 protein0101
Acetylcholine receptor subunit epsilon0101
Cholinesterase0101
Prostaglandin G/H synthase 20101
Cytochrome c oxidase subunit 10101
Transporter0101
Sodium-dependent serotonin transporter0101
Retina-specific copper amine oxidase0202
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B0202
cGMP-specific 3',5'-cyclic phosphodiesterase0303
Endothelin-1 receptor0101
Phosphodiesterase 0101
Catechol O-methyltransferase0012
ATP-binding cassette sub-family C member 80202
ATP-sensitive inward rectifier potassium channel 110202
Thrombin 0011
Neuromedin-U receptor 20011
Chain A, ADENINE-N6-DNA-METHYLTRANSFERASE TAQI0011
Chain A, Adenine-n6-dna-methyltransferase Taqi0011
Chain A, Histamine N-Methyltransferase0101
Chain A, Histamine N-Methyltransferase0101
Chain A, Modification Methylase Rsri0011
Chain A, Modification Methylase Rsri0011
Chain A, Ermc' Methyltransferase0101
Chain A, Ermc' Rrna Methyltransferase0101
Chain A, Uroporphyrin-III C-methyltransferase0101
Chain B, ADENINE-N6-DNA-METHYLTRANSFERASE TAQI0011
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase0011
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase0011
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase0011
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase0011
tRNA (cytosine(38)-C(5))-methyltransferase0112
Protein arginine N-methyltransferase 50101
Histone-lysine N-methyltransferase SUV39H10202
Adenosylhomocysteinase0001
Protein arginine N-methyltransferase 30101
Indolethylamine N-methyltransferase0101
Histone-lysine N-methyltransferase NSD20101
Adenosylhomocysteinase0001
Phenylethanolamine N-methyltransferase0101
rRNA adenine N-6-methyltransferase0101
Nicotinamide N-methyltransferase0101
tRNA (guanine-N(1)-)-methyltransferase0011
Histone-lysine N-methyltransferase SETDB10101
Retinoblastoma-binding protein 50101
Histone-lysine N-methyltransferase EZH20202
tRNA (guanine-N(1)-)-methyltransferase0011
N6-adenosine-methyltransferase catalytic subunit0101
Histone-arginine methyltransferase CARM10101
Histone-lysine N-methyltransferase KMT5C0101
Histone-lysine N-methyltransferase EZH10101
Methylosome protein 500101
Protein dpy-30 homolog0101
Histamine N-methyltransferase0001
Histone-lysine N-methyltransferase SUV39H20101
tRNA (guanine-N(1)-)-methyltransferase0011
N-lysine methyltransferase SMYD20101
Protein arginine N-methyltransferase 70101
DNA (cytosine-5)-methyltransferase 3B0101
Set1/Ash2 histone methyltransferase complex subunit ASH20101
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, 146aa long hypothetical transcriptional regulator0011
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain B, Anthranilate phosphoribosyltransferase0101
Chain C, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Anthranilate phosphoribosyltransferase0101
Tyrosine-protein phosphatase YopH0101
Ubiquitin-like domain-containing CTD phosphatase 10101
B-cell CLL/lymphoma 9 protein0202
Cadherin-10101
Pancreatic triacylglycerol lipase0101
Catenin beta-10213
Transcription factor 7-like 20101
Alanine aminotransferase 10002
Chain A, Proto-oncogene tyrosine-protein kinase Src0101
Chain A, Erk20101
Mitogen-activated protein kinase 20101
Mitogen-activated protein kinase 14 0112
P2X purinoceptor 70101
P2X purinoceptor 70101
Transient receptor potential cation channel subfamily M member 10101
Programmed cell death protein 10101
Programmed cell death 1 ligand 10101
Sterol O-acyltransferase 20101
Neuraminidase0101
photoreceptor-specific nuclear receptor0101
Cholecystokinin receptor type A0101
Eukaryotic translation initiation factor 4E0011
Peptidyl-prolyl cis-trans isomerase FKBP1A0101
Peptidyl-prolyl cis-trans isomerase FKBP1B0022
Peptidyl-prolyl cis-trans isomerase FKBP50202
Programmed cell death protein 40011
Serine/threonine-protein kinase mTOR 0101
Sulfate anion transporter 10001
C-X-C chemokine receptor type 5 isoform 10101
Endoglycoceramidase II 0001
cAMP-dependent protein kinase catalytic subunit alpha 0101
Sphingosine 1-phosphate receptor 20112
Sphingosine 1-phosphate receptor 40112
Sphingosine 1-phosphate receptor 30112
Sphingosine 1-phosphate receptor 50112
Chain A, Mineralocorticoid receptor0101
Chain A, Mineralocorticoid receptor0101
Orexin receptor type 10001
Cathepsin B0101
Thymidine kinase, cytosolic 0104
Substance-P receptor0202
Neuromedin-K receptor0011
Substance-K receptor0112
Neuromedin-K receptor0112
Substance-K receptor0101
Substance-K receptor0101
Growth hormone secretagogue receptor type 10011
Chain A, MALTOPORIN0011
Chain B, MALTOPORIN0011
ATP-dependent 6-phosphofructokinase0101
Dihydropteroate synthase0101
Cytochrome P450 2C180202
Chain A, Glutathione S-transferase0101
Fibroblast growth factor 10011
fMet-Leu-Phe receptor0101
Hematopoietic prostaglandin D synthase0101
Transcription regulator protein BACH10101
Transcription factor MafK 0101
NAD0003
Kelch-like ECH-associated protein 10123
Kelch-like ECH-associated protein 10001
D(2) dopamine receptor0101
15-hydroxyprostaglandin dehydrogenase [NAD(+)]0202
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0202
Splicing factor 3B subunit 30101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain B, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase0101
cGMP-specific 3',5'-cyclic phosphodiesterase0123
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha0101
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'0101
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta0101
Chain A, CES1 protein0101
Emopamil-binding protein-like0202
7-dehydrocholesterol reductase0112
Corticotropin releasing hormone receptor 20101
Lysine-specific demethylase 4B0101
ATP-dependent molecular chaperone HSC820101
Heat-shock protein0101
Putative heat shock protein HSP 90-alpha A40101
Polycomb protein SUZ120101
Chain A, Prostatic Acid Phosphatase0101
Bile salt export pump0002
Sodium/bile acid cotransporter0001
Ileal sodium/bile acid cotransporter0001
Ileal sodium/bile acid cotransporter0001
Solute carrier organic anion transporter family member 4A10002
Parathyroid hormone/parathyroid hormone-related peptide receptor0113
Dihydroxyacetone phosphate acyltransferase0001
Tetracycline resistance protein, class B0001
Neutrophil collagenase0303
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 0101
Chain A, Pyridoxal kinase0101
Chain A, Pyridoxal Kinase0101
Adenosine receptor A10202
Adenosine receptor A10101
Chain A, ykoF0011
Chain B, ykoF0011
Chain A, ThiT0011
Thiamine transporter ThiT0011
Transketolase0011
Thiamine-binding periplasmic protein0011
Urease subunit alpha0101
Urease subunit beta 0101
Thymidine kinase 0102
Thymidine phosphorylase0001
Thymidine phosphorylase0001
Thymidylate kinase0101
Thymidine kinase0001
Thymidylate kinase0202
Thymidine kinase 0204
Thymidine kinase0103
Thymidine phosphorylase0101
Chain X, Thyroid hormone receptor beta-10022
Chain X, Thyroid hormone receptor beta-10022
Proliferating cell nuclear antigen0202
Malate dehydrogenase, mitochondrial0101
Monocarboxylate transporter 80001
Solute carrier organic anion transporter family member 1C10001
Chain A, Tyrosine-protein kinase0101
Chain A, Tyrosine-protein kinase0101
Chain A, Tyrosine-protein kinase JAK20101
Tyrosine-protein kinase JAK30101
Tyrosine-protein kinase JAK20101
Tyrosine-protein kinase JAK30101
Cytochrome P450 4B10101
Cytochrome P450 2A70101
Cytochrome P450 2F10101
Cytochrome P450 4F80101
Cytochrome P450 4A110101
Cytochrome P450 4F30101
Cytochrome P450 4A220101
Vitamin D 25-hydroxylase0101
Cytochrome P450 2U10101
Cytochrome P450 2W10101
Cytochrome P450 2S10101
Cytochrome P450 3A43 0101
REST corepressor 30101
Chain A, X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with trehalose0101
Chain A, X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with cellobiose0101
Chain A, X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with maltose0101
Trehalose-phosphatase0101
Chain A, Nuclear Receptor ROR-beta0101
Nuclear receptor ROR-alpha0101
Nuclear receptor ROR-beta0101
procathepsin L isoform 1 preproprotein0101
Chain A, PAPAIN1001
putative alpha-glucosidase1001
Janus kinase 2 (a protein tyrosine kinase)0101
Chain A, enoyl-acyl carrier reductase0101
Chain C, enoyl-acyl carrier reductase0101
Chain A, enoyl-acyl carrier reductase0101
Chain C, enoyl-acyl carrier reductase0101
Chain A, enoyl-acyl carrier reductase0101
Chain C, enoyl-acyl carrier reductase0101
Chain A, Repressor0011
twin arginine protein translocation system - TatA protein0002
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI0101
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI0101
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI0202
Enoyl-acyl carrier reductase0101
Enoyl-ACP reductase II 0101
Diamine acetyltransferase 10001
Thialysine N-epsilon-acetyltransferase0001
Calcium-dependent protein kinase 40101
Chain A, Dihydrofolate Reductase0011
Chain A, Dihydrofolate reductase0101
Chain A, dihydrofolate reductase (DHFR)0101
Chain A, Dihydrofolate reductase0101
Chain A, Dihydrofolate reductase0101
Dihydrofolate reductase 0102
Dihydrofolate reductase type 10102
Dihydrofolate reductase0101
Dihydrofolate reductase0101
NH(3)-dependent NAD(+) synthetase0101
Dihydrofolate reductase type 1 from Tn40030101
Dihydrofolate reductase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Trace amine-associated receptor 50011
Dihydrofolate reductase 0101
Dihydrofolate reductase 0101
Proteinase-activated receptor 20101
Forkhead box protein M10202
Chain A, CARBONIC ANHYDRASE II0101
Dopamine beta-hydroxylase0101
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Tryprostatin B synthase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Chain A, Uracil-DNA Glycosylase0101
Chain A, Cytidine Deaminase0101
Uridine-cytidine kinase 1 0001
Basic phospholipase A2 10101
Hemagglutinin0011
Basic phospholipase A2 PLA-A0101
Acidic phospholipase A2 EC-I0101
Ubiquitin carboxyl-terminal hydrolase 70101
Ubiquitin carboxyl-terminal hydrolase 470101
Sentrin-specific protease 10101
Chain A, Arginase 10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
D-alanyl-D-alanine dipeptidase0101
Glycoprotein0101
Catechol O-methyltransferase0101
Dual specificity protein phosphatase 10101
M-phase inducer phosphatase 30101
Receptor protein-tyrosine kinase 0101
Dual specificity protein phosphatase 60101
Ubiquitin carboxyl-terminal hydrolase isozyme L30101
Ubiquitin carboxyl-terminal hydrolase isozyme L10101
Sterol 14-alpha-demethylase0011
14-alpha sterol demethylase 0011
Lanosterol 14-alpha demethylase0011
Sterol 14-alpha demethylase0011
14-alpha sterol demethylase 0011
14-alpha sterol demethylase 0011
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
Proto-oncogene Wnt-30012
Secreted frizzled-related protein 10101
Arachidonate 5-lipoxygenase0101
Telomere resolvase ResT0101
Genome polyprotein0101
Chain A, Tankyrase-20011
Chain A, Tankyrase-10101
Chain A, Tankyrase-10101
Protein Wnt-3a0101
Protein Wnt-3a0101
Protein mono-ADP-ribosyltransferase PARP60101
Protein mono-ADP-ribosyltransferase PARP140101
Protein mono-ADP-ribosyltransferase PARP160101
Protein mono-ADP-ribosyltransferase PARP110101
Protein mono-ADP-ribosyltransferase PARP40101
Axin-20011
Protein mono-ADP-ribosyltransferase PARP30101
Gastrin/cholecystokinin type B receptor0101
Farnesyl diphosphate synthase0202
Alkaline phosphatase, tissue-nonspecific isozyme 0101
Zinc finger protein GLI20101
Ectonucleoside triphosphate diphosphohydrolase 10001
Tumor necrosis factor ligand superfamily member 110101
Sphingosine-1-phosphate lyase 10101
Amine oxidase [flavin-containing]0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]