Target type: molecularfunction
The action of a molecule that contributes to the structural integrity of the ribosome. [GOC:mah]
Ribosomal proteins are fundamental components of ribosomes, the molecular machines responsible for protein synthesis. They play a crucial role in the structural integrity and functional efficiency of ribosomes. Ribosomal proteins are involved in several aspects of ribosome function, including:
1. **Ribosome Assembly:** They provide the structural framework for the ribosome, ensuring its correct assembly and stability. Each ribosomal protein interacts with specific ribosomal RNA (rRNA) molecules and other proteins, forming a complex network that contributes to the overall structure and function of the ribosome.
2. **Ribosome Stability:** They help maintain the structural integrity of the ribosome, preventing its disassembly during translation. This stability is essential for the efficient and accurate synthesis of proteins.
3. **mRNA Binding:** Some ribosomal proteins participate in the binding of messenger RNA (mRNA) to the ribosome. This interaction is crucial for initiating protein synthesis and ensuring that the correct mRNA is translated.
4. **tRNA Binding:** Other ribosomal proteins play a role in the binding of transfer RNA (tRNA) molecules to the ribosome. tRNAs carry amino acids to the ribosome, where they are incorporated into the growing polypeptide chain.
5. **Catalytic Activity:** While rRNA is the primary catalytic component of the ribosome, some ribosomal proteins contribute to the catalytic activity of the ribosome. They facilitate the formation of peptide bonds between amino acids, the crucial step in protein synthesis.
6. **Regulation of Translation:** Certain ribosomal proteins are involved in the regulation of protein synthesis. They can influence the rate of translation initiation, elongation, and termination.
7. **Ribosome Biogenesis:** They participate in the synthesis and assembly of new ribosomes, ensuring the continuous production of ribosomes needed for protein synthesis.'
"
| Protein | Definition | Taxonomy |
|---|---|---|
| 50S ribosomal protein L36 2 | A large ribosomal subunit protein bL36B that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:Q2EEQ2] | Escherichia coli K-12 |
| 50S ribosomal protein L25 | A large ribosomal subunit protein bL25 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P68919] | Escherichia coli K-12 |
| 30S ribosomal protein S21 | A small ribosomal subunit protein bS21 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P68679] | Escherichia coli K-12 |
| 50S ribosomal protein L5 | A large ribosomal subunit protein uL5 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P62399] | Escherichia coli K-12 |
| 50S ribosomal protein L22 | A large ribosomal subunit protein uL22 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P61175] | Escherichia coli K-12 |
| 50S ribosomal protein L4 | A large ribosomal subunit protein uL4 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P60723] | Escherichia coli K-12 |
| 50S ribosomal protein L24 | A large ribosomal subunit protein uL24 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P60624] | Escherichia coli K-12 |
| 50S ribosomal protein L3 | A large ribosomal subunit protein uL3 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P60438] | Escherichia coli K-12 |
| 50S ribosomal protein L2 | A large ribosomal subunit protein uL2 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P60422] | Escherichia coli K-12 |
| 50S ribosomal protein L18 | A large ribosomal subunit protein uL18 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0C018] | Escherichia coli K-12 |
| 30S ribosomal protein S1 | A small ribosomal subunit protein bS1 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0AG67] | Escherichia coli K-12 |
| 30S ribosomal protein S17 | A small ribosomal subunit protein uS17 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0AG63] | Escherichia coli K-12 |
| 30S ribosomal protein S14 | A small ribosomal subunit protein uS14 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0AG59] | Escherichia coli K-12 |
| 50S ribosomal protein L6 | A large ribosomal subunit protein uL6 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0AG55] | Escherichia coli K-12 |
| 50S ribosomal protein L30 | A large ribosomal subunit protein uL30 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0AG51] | Escherichia coli K-12 |
| 50S ribosomal protein L21 | A large ribosomal subunit protein bL21 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0AG48] | Escherichia coli K-12 |
| 50S ribosomal protein L17 | A large ribosomal subunit protein bL17 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0AG44] | Escherichia coli K-12 |
| 30S ribosomal protein S15 | A small ribosomal subunit protein uS15 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0ADZ4] | Escherichia coli K-12 |
| 50S ribosomal protein L23 | A large ribosomal subunit protein uL23 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0ADZ0] | Escherichia coli K-12 |
| 50S ribosomal protein L16 | A large ribosomal subunit protein uL16 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0ADY7] | Escherichia coli K-12 |
| 50S ribosomal protein L14 | A large ribosomal subunit protein uL14 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0ADY3] | Escherichia coli K-12 |
| 50S ribosomal protein L13 | A large ribosomal subunit protein uL13 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0AA10] | Escherichia coli K-12 |
| 30S ribosomal protein S9 | A prokaryotic-type small ribosomal subunit protein uS9 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7X3] | Escherichia coli K-12 |
| 30S ribosomal protein S8 | A small ribosomal subunit protein uS8 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7W7] | Escherichia coli K-12 |
| 30S ribosomal protein S5 | A small ribosomal subunit protein uS5 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7W1] | Escherichia coli K-12 |
| 30S ribosomal protein S4 | A small ribosomal subunit protein uS4 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7V8] | Escherichia coli K-12 |
| 30S ribosomal protein S3 | A small ribosomal subunit protein uS3 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7V3] | Escherichia coli K-12 |
| 30S ribosomal protein S2 | A small ribosomal subunit protein uS2 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7V0] | Escherichia coli K-12 |
| 30S ribosomal protein S20 | A small ribosomal subunit protein bS20 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7U7] | Escherichia coli K-12 |
| 30S ribosomal protein S19 | A small ribosomal subunit protein uS19 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7U3] | Escherichia coli K-12 |
| 30S ribosomal protein S18 | A small ribosomal subunit protein bS18 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7T7] | Escherichia coli K-12 |
| 30S ribosomal protein S16 | A small ribosomal subunit protein bS16 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7T3] | Escherichia coli K-12 |
| 30S ribosomal protein S13 | A small ribosomal subunit protein uS13 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7S9] | Escherichia coli K-12 |
| 30S ribosomal protein S12 | A small ribosomal subunit protein uS12 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7S3] | Escherichia coli K-12 |
| 30S ribosomal protein S11 | A small ribosomal subunit protein uS11 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7R9] | Escherichia coli K-12 |
| 30S ribosomal protein S10 | A small ribosomal subunit protein uS10 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7R5] | Escherichia coli K-12 |
| 50S ribosomal protein L36 | A large ribosomal subunit protein bL36A that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7Q6] | Escherichia coli K-12 |
| 50S ribosomal protein L35 | A large ribosomal subunit protein bL35 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7Q1] | Escherichia coli K-12 |
| 50S ribosomal protein L34 | A large ribosomal subunit protein bL34 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7P5] | Escherichia coli K-12 |
| 50S ribosomal protein L33 | A large ribosomal subunit protein bL33 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7N9] | Escherichia coli K-12 |
| 50S ribosomal protein L32 | A large ribosomal subunit protein bL32 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7N4] | Escherichia coli K-12 |
| 50S ribosomal protein L31 type B | A large ribosomal subunit protein bL31B that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7N1] | Escherichia coli K-12 |
| 50S ribosomal protein L31 | A large ribosomal subunit protein bL31 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7M9] | Escherichia coli K-12 |
| 50S ribosomal protein L29 | A large ribosomal subunit protein uL29 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7M6] | Escherichia coli K-12 |
| 50S ribosomal protein L28 | A large ribosomal subunit protein bL28 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7M2] | Escherichia coli K-12 |
| 50S ribosomal protein L27 | A large ribosomal subunit protein bL27 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7L8] | Escherichia coli K-12 |
| 50S ribosomal protein L20 | A large ribosomal subunit protein bL20 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7L3] | Escherichia coli K-12 |
| 50S ribosomal protein L1 | A large ribosomal subunit protein uL1 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7L0] | Escherichia coli K-12 |
| 50S ribosomal protein L19 | A large ribosomal subunit protein bL19 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7K6] | Escherichia coli K-12 |
| 50S ribosomal protein L7/L12 | A large ribosomal subunit protein bL12 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7K2] | Escherichia coli K-12 |
| 50S ribosomal protein L11 | A large ribosomal subunit protein uL11 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7J7] | Escherichia coli K-12 |
| 50S ribosomal protein L10 | A large ribosomal subunit protein uL10 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A7J3] | Escherichia coli K-12 |
| 50S ribosomal protein L15 | A large ribosomal subunit protein uL15 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P02413] | Escherichia coli K-12 |
| 30S ribosomal protein S7 | A small ribosomal subunit protein uS7 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P02359] | Escherichia coli K-12 |
| 30S ribosomal protein S6 | A small ribosomal subunit protein bS6 that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P02358] | Escherichia coli K-12 |
| 60S ribosomal protein L36 | A large ribosomal subunit protein eL36 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q9Y3U8] | Homo sapiens (human) |
| 60S ribosomal protein L18 | A large ribosomal subunit protein eL18 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q07020] | Homo sapiens (human) |
| 60S ribosomal protein L6 | A large ribosomal subunit protein eL6 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q02878] | Homo sapiens (human) |
| 60S ribosomal protein L18a | A large ribosomal subunit protein eL20 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q02543] | Homo sapiens (human) |
| 60S ribosomal protein L19 | A large ribosomal subunit protein eL19 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P84098] | Homo sapiens (human) |
| 60S ribosomal protein L36a | A large ribosomal subunit protein eL42 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P83881] | Homo sapiens (human) |
| 60S ribosomal protein L24 | A large ribosomal subunit protein eL24 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P83731] | Homo sapiens (human) |
| 40S ribosomal protein S21 | A small ribosomal subunit protein eS21 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P63220] | Homo sapiens (human) |
| 60S ribosomal protein L38 | A large ribosomal subunit protein eL38 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P63173] | Homo sapiens (human) |
| Ubiquitin-40S ribosomal protein S27a | A ubiquitin-ribosomal protein eS31 fusion protein that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62979] | Homo sapiens (human) |
| 60S ribosomal protein L41 | A small ribosomal subunit protein eS32 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62945] | Homo sapiens (human) |
| 60S ribosomal protein L8 | A eukaryotic-type large ribosomal subunit protein uL2 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62917] | Homo sapiens (human) |
| 60S ribosomal protein L11 | A eukaryotic-type large ribosomal subunit protein uL5 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62913] | Homo sapiens (human) |
| 60S ribosomal protein L32 | A large ribosomal subunit protein eL32 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62910] | Homo sapiens (human) |
| 60S ribosomal protein L10a | A eukaryotic-type large ribosomal subunit protein uL1 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62906] | Homo sapiens (human) |
| 60S ribosomal protein L31 | A large ribosomal subunit protein eL31 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62899] | Homo sapiens (human) |
| 60S ribosomal protein L39 | A large ribosomal subunit protein eL39 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62891] | Homo sapiens (human) |
| 60S ribosomal protein L30 | A large ribosomal subunit protein eL30 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62888] | Homo sapiens (human) |
| 40S ribosomal protein S30 | A ubiquitin-like FUBI-ribosomal protein eS30 fusion protein that is encoded in the genome of human. [PRO:DAN, UniProtKB:P62861] | Homo sapiens (human) |
| 40S ribosomal protein S28 | A small ribosomal subunit protein eS28 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62857] | Homo sapiens (human) |
| 40S ribosomal protein S26 | A small ribosomal subunit protein eS26 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62854] | Homo sapiens (human) |
| 40S ribosomal protein S25 | A small ribosomal subunit protein eS25 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62851] | Homo sapiens (human) |
| 40S ribosomal protein S24 | A small ribosomal subunit protein eS24 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62847] | Homo sapiens (human) |
| 40S ribosomal protein S15 | A eukaryotic-type small ribosomal subunit protein uS19 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62841] | Homo sapiens (human) |
| 60S ribosomal protein L23 | A eukaryotic-type large ribosomal subunit protein uL14 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62829] | Homo sapiens (human) |
| 40S ribosomal protein S6 | A small ribosomal subunit protein eS6 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62753] | Homo sapiens (human) |
| 60S ribosomal protein L23a | A eukaryotic-type large ribosomal subunit protein uL23 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62750] | Homo sapiens (human) |
| 40S ribosomal protein S4, X isoform | A small ribosomal subunit protein eS4, X isoform that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62701] | Homo sapiens (human) |
| 60S ribosomal protein L7a | A large ribosomal subunit protein eL8 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62424] | Homo sapiens (human) |
| 40S ribosomal protein S11 | A eukaryotic-type small ribosomal subunit protein uS17 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62280] | Homo sapiens (human) |
| 40S ribosomal protein S13 | A eukaryotic-type small ribosomal subunit protein uS15 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62277] | Homo sapiens (human) |
| 40S ribosomal protein S29 | A eukaryotic-type small ribosomal subunit protein uS14 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62273] | Homo sapiens (human) |
| 40S ribosomal protein S18 | A eukaryotic-type small ribosomal subunit protein uS13 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62269] | Homo sapiens (human) |
| 40S ribosomal protein S23 | A eukaryotic-type small ribosomal subunit protein uS12 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62266] | Homo sapiens (human) |
| 40S ribosomal protein S14 | A eukaryotic-type small ribosomal subunit protein uS11 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62263] | Homo sapiens (human) |
| 40S ribosomal protein S16 | A eukaryotic-type small ribosomal subunit protein uS9 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62249] | Homo sapiens (human) |
| 40S ribosomal protein S15a | A eukaryotic-type small ribosomal subunit protein uS8 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62244] | Homo sapiens (human) |
| 40S ribosomal protein S8 | A small ribosomal subunit protein eS8 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62241] | Homo sapiens (human) |
| 40S ribosomal protein S7 | A small ribosomal subunit protein eS7 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P62081] | Homo sapiens (human) |
| 60S ribosomal protein L37 | A large ribosomal subunit protein eL37 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P61927] | Homo sapiens (human) |
| 60S ribosomal protein L37a | A large ribosomal subunit protein eL43 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P61513] | Homo sapiens (human) |
| 60S ribosomal protein L27 | A large ribosomal subunit protein eL27 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P61353] | Homo sapiens (human) |
| 60S ribosomal protein L15 | A large ribosomal subunit protein eL15 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P61313] | Homo sapiens (human) |
| 60S ribosomal protein L26 | A eukaryotic-type large ribosomal subunit protein uL24 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P61254] | Homo sapiens (human) |
| 40S ribosomal protein S3a | A small ribosomal subunit protein eS1 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P61247] | Homo sapiens (human) |
| 40S ribosomal protein S20 | A eukaryotic-type small ribosomal subunit protein uS10 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P60866] | Homo sapiens (human) |
| 60S ribosomal protein L14 | A large ribosomal subunit protein eL14 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P50914] | Homo sapiens (human) |
| 60S ribosomal protein L34 | A large ribosomal subunit protein eL34 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P49207] | Homo sapiens (human) |
| 60S ribosomal protein L29 | A large ribosomal subunit protein eL29 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P47914] | Homo sapiens (human) |
| 40S ribosomal protein S10 | A small ribosomal subunit protein eS10 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P46783] | Homo sapiens (human) |
| 40S ribosomal protein S5 | A eukaryotic-type small ribosomal subunit protein uS7 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P46782] | Homo sapiens (human) |
| 40S ribosomal protein S9 | A eukaryotic-type small ribosomal subunit protein uS4 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P46781] | Homo sapiens (human) |
| 60S ribosomal protein L28 | A large ribosomal subunit protein eL28 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P46779] | Homo sapiens (human) |
| 60S ribosomal protein L21 | A large ribosomal subunit protein eL21 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P46778] | Homo sapiens (human) |
| 60S ribosomal protein L5 | A eukaryotic-type large ribosomal subunit protein uL18 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P46777] | Homo sapiens (human) |
| 60S ribosomal protein L27a | A eukaryotic-type large ribosomal subunit protein uL15 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P46776] | Homo sapiens (human) |
| 60S ribosomal protein L35 | A eukaryotic-type large ribosomal subunit protein uL29 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P42766] | Homo sapiens (human) |
| 40S ribosomal protein S27 | A small ribosomal subunit protein eS27 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P42677] | Homo sapiens (human) |
| 60S ribosomal protein L13a | A eukaryotic-type large ribosomal subunit protein uL13 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P40429] | Homo sapiens (human) |
| 60S ribosomal protein L3 | A eukaryotic-type large ribosomal subunit protein uL3 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P39023] | Homo sapiens (human) |
| 40S ribosomal protein S19 | A small ribosomal subunit protein eS19 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P39019] | Homo sapiens (human) |
| 60S ribosomal protein L4 | A eukaryotic-type large ribosomal subunit protein uL4 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P36578] | Homo sapiens (human) |
| 60S ribosomal protein L22 | A large ribosomal subunit protein eL22 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P35268] | Homo sapiens (human) |
| 60S ribosomal protein L9 | A eukaryotic-type large ribosomal subunit protein uL6 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P32969] | Homo sapiens (human) |
| 60S ribosomal protein L12 | A eukaryotic-type large ribosomal subunit protein uL11 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P30050] | Homo sapiens (human) |
| 60S ribosomal protein L10 | A eukaryotic-type large ribosomal subunit protein uL16 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P27635] | Homo sapiens (human) |
| 60S ribosomal protein L13 | A large ribosomal subunit protein eL13 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P26373] | Homo sapiens (human) |
| 40S ribosomal protein S12 | A small ribosomal subunit protein eS12 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P25398] | Homo sapiens (human) |
| 40S ribosomal protein S3 | A eukaryotic-type small ribosomal subunit protein uS3 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P23396] | Homo sapiens (human) |
| 40S ribosomal protein S4, Y isoform 1 | A small ribosomal subunit protein eS4, Y isoform 1 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P22090] | Homo sapiens (human) |
| 60S ribosomal protein L17 | A eukaryotic-type large ribosomal subunit protein uL22 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P18621] | Homo sapiens (human) |
| 60S ribosomal protein L7 | A eukaryotic-type large ribosomal subunit protein uL30 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P18124] | Homo sapiens (human) |
| 60S ribosomal protein L35a | A large ribosomal subunit protein eL33 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P18077] | Homo sapiens (human) |
| 40S ribosomal protein S2 | A eukaryotic-type small ribosomal subunit protein uS5 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P15880] | Homo sapiens (human) |
| 40S ribosomal protein SA | A eukaryotic-type small ribosomal subunit protein uS2 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P08865] | Homo sapiens (human) |
| 40S ribosomal protein S17 | A small ribosomal subunit protein eS17 that is encoded in the genome of human. [PRO:DAN, UniProtKB:P08708] | Homo sapiens (human) |
| 60S acidic ribosomal protein P0 | A eukaryotic-type large ribosomal subunit protein uL10 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P05388] | Homo sapiens (human) |
| 60S acidic ribosomal protein P1 | A large ribosomal subunit protein P1 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P05386] | Homo sapiens (human) |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 | An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 that is encoded in the genome of human. [PRO:DNx] | Homo sapiens (human) |
| Compound | Definition | Classes | Roles |
|---|---|---|---|
| chloramphenicol | Amphenicol: Chloramphenicol and its derivatives. | C-nitro compound; carboxamide; diol; organochlorine compound | antibacterial drug; antimicrobial agent; Escherichia coli metabolite; geroprotector; Mycoplasma genitalium metabolite; protein synthesis inhibitor |
| framycetin | framycetin : A tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine B. Framycetin: A component of NEOMYCIN that is produced by Streptomyces fradiae. On hydrolysis it yields neamine and neobiosamine B. (From Merck Index, 11th ed) | aminoglycoside | allergen; antibacterial drug; Escherichia coli metabolite |
| erythromycin | erythromycin : Any of several wide-spectrum macrolide antibiotics obtained from actinomycete Saccharopolyspora erythraea (formerly known as Streptomyces erythraeus). erythromycin A : An erythromycin that consists of erythronolide A having 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl and 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl residues attahced at positions 4 and 6 respectively. Erythromycin: A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins. | cyclic ketone; erythromycin | |
| neamine | neamine : 2-Deoxy-D-streptamine glycosylated at the 4-oxygen with a 6-amino-alpha-D-glucosaminyl group. neamine: fragment of NEOMYCIN B; structure in first source | 2,6-dideoxy-alpha-D-glucoside; aminoglycoside | antibacterial agent |
| florfenicol | florfenicol : A carboxamide that is the N-dichloroacetyl derivative of (1R,2S)-2-amino-3-fluoro-1-[4-(methanesulfonyl)phenyl]propan-1-ol. A synthetic veterinary antibiotic that is used for treatment of bovine respiratory disease and foot rot; also used in aquaculture. florfenicol: structure given in first source | organochlorine compound; organofluorine compound; secondary alcohol; secondary carboxamide; sulfone | antimicrobial agent |
| antibiotic g 418 | antibiotic G 418: from Micromonospora rhodorangea | ||
| paromomycin | paromomycin : An amino cyclitol glycoside that is the 1-O-(2-amino-2-deoxy-alpha-D-glucopyranoside) and the 3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranoside of 4,6-diamino-2,3-dihydroxycyclohexane (the 1R,2R,3S,4R,6S diastereoisomer). It is obtained from various Streptomyces species. A broad-spectrum antibiotic, it is used (generally as the sulfate salt) for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmaniasis. Paromomycin: An aminoglycoside antibacterial and antiprotozoal agent produced by species of STREPTOMYCES. | amino cyclitol glycoside; aminoglycoside antibiotic | anthelminthic drug; antibacterial drug; antiparasitic agent; antiprotozoal drug |
| puromycin | puromycins | antiinfective agent; antimicrobial agent; antineoplastic agent; EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor; EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor; nucleoside antibiotic; protein synthesis inhibitor | |
| netilmicin | Netilmicin: Semisynthetic 1-N-ethyl derivative of SISOMYCIN, an aminoglycoside antibiotic with action similar to gentamicin, but less ear and kidney toxicity. | ||
| linezolid | acetamides; morpholines; organofluorine compound; oxazolidinone | antibacterial drug; protein synthesis inhibitor | |
| zithromax | azithromycin : A macrolide antibiotic useful for the treatment of bacterial infections. Azithromycin: A semi-synthetic macrolide antibiotic structurally related to ERYTHROMYCIN. It has been used in the treatment of Mycobacterium avium intracellulare infections, toxoplasmosis, and cryptosporidiosis. | macrolide antibiotic | antibacterial drug; environmental contaminant; xenobiotic |
| tiamulin | tiamulin : A carbotricyclic compound that is pleuromutilin in which the hydroxyacetate group is replaced by a 2-{[2-(diethylamino)ethyl]sulfanyl}acetate group. An antibacterial drug, tiamulin is used in veterinary medicine (generally as its hydrogen fumarate salt) for the treatment of swine dysentery caused by Serpulina hyodysenteriae. tiamulin: 81723 HFU and tiamutin are for fumarate salt; prevents senescence in ascomycete; pleuromutilin derivative; RN given refers to ((3aS-(3aalpha,4beta,5alpha,6alpha,8beta,9alpha,9abeta,10S*))-isomer | carbotricyclic compound; carboxylic ester; cyclic ketone; organic sulfide; secondary alcohol; semisynthetic derivative; tertiary amino compound; tetracyclic diterpenoid | antibacterial drug |
| aurapten | aurapten: RN refers to (E)-isomer; structure given in first source auraptene : A member of the class of coumarins that is umbelliferone in which the phenolic hydrogen has been replaced by a geranyl group. Ii is isolated from several edible fruits and vegetables and exhibits a variety of therapeutic properties. | coumarins; monoterpenoid | antihypertensive agent; antineoplastic agent; antioxidant; apoptosis inducer; dopaminergic agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor; gamma-secretase modulator; gastrointestinal drug; hepatoprotective agent; matrix metalloproteinase inhibitor; neuroprotective agent; plant metabolite; PPARalpha agonist; vulnerary |
| hmr 3647 | |||
| josamycin | acetate ester; aldehyde; disaccharide derivative; glycoside; macrolide antibiotic; tertiary alcohol; tertiary amino compound | antibacterial drug; metabolite | |
| albocycline | albocycline: macrolide antibiotic isolated from Streptomyces bruneogriseus nov. sp. MCRL-0129; specifically anti-staphylococcal, including antibiotic-resistant strains; structure | macrolide | |
| marmin | marmin: structure in first source; RN given for (R-(E))-isomer | ||
| evernimicin | |||
| gentamicin sulfate | |||
| gentamicin sulfate | |||
| pristinamycin iib | virginiamycin M2: structure in first source | ||
| cem 101 | solithromycin: an antibacterial fluoroketolide; structure in first source | ||
| tetracycline | tetracycline : A broad-spectrum polyketide antibiotic produced by the Streptomyces genus of actinobacteria. Tetracycline: A naphthacene antibiotic that inhibits AMINO ACYL TRNA binding during protein synthesis. | ||
| eravacycline | eravacycline: has antibacterial activity | tetracyclines | |
| PF-06446846 | PF-06446846 : A triazolopyridine that is 3H-[1,2,3]triazolo[4,5-b]pyridine substituted by a 4-{(3-chloropyridin-2-yl)[(3R)-piperidin-3-yl]carbamoyl}phenyl group at position 3. It is a potent inhibitor of PCSK9. PF-06446846: inhibits translation of PCSK9 ;structure in first source | benzamides; monochloropyridine; piperidines; tertiary carboxamide; triazolopyridine | antilipemic drug; EC 3.4.21.61 (kexin) inhibitor |