tetracycline and Leukemia-P388

tetracycline has been researched along with Leukemia-P388* in 1 studies

Other Studies

1 other study(ies) available for tetracycline and Leukemia-P388

Article	Year
Spectroscopic and biological studies of spin-labeled tetracycline. Life sciences, 1992, Volume: 50, Issue:20 A new nitroxyl labeled tetracycline is synthesized. Proton NMR experiments of tetracycline, spin-labeled tetracycline, and the diamagnetic reduced form in DMSO-d6 are reported. The signals observed in the NMR spectra are all assigned. The NMR data revealed that the spin label is attached to the C-2 amide group on ring A of tetracycline. The spin-labeled tetracycline is also tested in vitro for antitumor activity and is found to be active against leukemia P338/ADR cell line and in melanoma LOX cell line. Topics: Animals; Antineoplastic Agents; Electron Spin Resonance Spectroscopy; Leukemia P388; Magnetic Resonance Spectroscopy; Melanoma; Spin Labels; Tetracycline; Tumor Cells, Cultured	1992

Article

Year

Spectroscopic and biological studies of spin-labeled tetracycline.

Life sciences, 1992, Volume: 50, Issue:20

A new nitroxyl labeled tetracycline is synthesized. Proton NMR experiments of tetracycline, spin-labeled tetracycline, and the diamagnetic reduced form in DMSO-d6 are reported. The signals observed in the NMR spectra are all assigned. The NMR data revealed that the spin label is attached to the C-2 amide group on ring A of tetracycline. The spin-labeled tetracycline is also tested in vitro for antitumor activity and is found to be active against leukemia P338/ADR cell line and in melanoma LOX cell line.

Topics: Animals; Antineoplastic Agents; Electron Spin Resonance Spectroscopy; Leukemia P388; Magnetic Resonance Spectroscopy; Melanoma; Spin Labels; Tetracycline; Tumor Cells, Cultured

1992