An alkaloid based on a cinchonan skeleton.
ChEBI ID: 51323
Member | Definition | Role |
---|---|---|
6'-hydroxycinchonidine | cupreine | |
aricine | 4-quinolyl(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanol | |
cinchonidine | 8-epi-Cinchonan in which a hydrogen at position 9 is substituted by hydroxy (R configuration). A diasteroisomer of cinchonine, it occurs in the bark of most varieties of Cinchona shrubs, and is frequently used for directing chirality in asymmetric synthesis. | cinchonidine |
cinchonine | Cinchonan in which a hydrogen at position 9 is substituted by hydroxy (S configuration). It occurs in the bark of most varieties of Cinchona shrubs, and is frequently used for directing chirality in asymmetric synthesis. | cinchonine |
epicinchonine | (R)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(4-quinolinyl)methanol | |
ethylhydrocupreine | A cinchona alkaloid consisting of 10,11-dihydrocinchonan bearing hydroxy and ethoxy substituents at positions 9 and 6' respectively. | optochin |
hydroquinidine | hydroquinine | |
quinidine | A cinchona alkaloid consisting of cinchonine with the hydrogen at the 6-position of the quinoline ring substituted by methoxy. | quinidine |
quinine | A cinchona alkaloid that is cinchonidine in which the hydrogen at the 6-position of the quinoline ring is substituted by methoxy. | quinine |
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
---|---|---|
pre-1990 | 6,440 (53.22) | 18.7374 |
1990's | 2,043 (16.88) | 18.2507 |
2000's | 1,744 (14.41) | 29.6817 |
2010's | 1,511 (12.49) | 24.3611 |
2020's | 362 (2.99) | 2.80 |
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
---|---|---|
Trials | 814 (5.86%) | 5.53% |
Reviews | 798 (5.75%) | 6.00% |
Case Studies | 1,167 (8.40%) | 4.05% |
Observational | 15 (0.11%) | 0.25% |
Other | 11,092 (79.88%) | 84.16% |