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cinchona alkaloid

An alkaloid based on a cinchonan skeleton.

ChEBI ID: 51323

Members (9)

MemberDefinitionRole
6'-hydroxycinchonidinecupreine
aricine4-quinolyl(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanol
cinchonidine8-epi-Cinchonan in which a hydrogen at position 9 is substituted by hydroxy (R configuration). A diasteroisomer of cinchonine, it occurs in the bark of most varieties of Cinchona shrubs, and is frequently used for directing chirality in asymmetric synthesis.cinchonidine
cinchonineCinchonan in which a hydrogen at position 9 is substituted by hydroxy (S configuration). It occurs in the bark of most varieties of Cinchona shrubs, and is frequently used for directing chirality in asymmetric synthesis.cinchonine
epicinchonine(R)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(4-quinolinyl)methanol
ethylhydrocupreineA cinchona alkaloid consisting of 10,11-dihydrocinchonan bearing hydroxy and ethoxy substituents at positions 9 and 6' respectively.optochin
hydroquinidinehydroquinine
quinidineA cinchona alkaloid consisting of cinchonine with the hydrogen at the 6-position of the quinoline ring substituted by methoxy.quinidine
quinineA cinchona alkaloid that is cinchonidine in which the hydrogen at the 6-position of the quinoline ring is substituted by methoxy.quinine

Research

Studies (12,100)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19906,440 (53.22)18.7374
1990's2,043 (16.88)18.2507
2000's1,744 (14.41)29.6817
2010's1,511 (12.49)24.3611
2020's362 (2.99)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials814 (5.86%)5.53%
Reviews798 (5.75%)6.00%
Case Studies1,167 (8.40%)4.05%
Observational15 (0.11%)0.25%
Other11,092 (79.88%)84.16%