Page last updated: 2024-08-05 11:47:50
dinitrile
A dinitrile is a compound containing two nitrile groups.
ChEBI ID: 51308
Members (6)
Member | Definition | Role |
---|---|---|
cyanogen | A dinitrile that is ethane substituted by two cyano groups. | oxalonitrile |
dicyanmethane | A dinitrile that is methane substituted by two cyano groups. | malononitrile |
dithianone | A naphthodithiin that is 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiin which is substituted by nitrile groups at positions 2 and 3. It is a broad spectrum fungicide used to control scab, downy mildew, rust, and leaf spot in the commercial growing of grapes and other fruit, citrus, coffee, and vegetables. | dithianon |
etravirine | An aminopyrimidine that consists of 2,6-diaminopyrimidine bearing a bromo substituent at position 5, a 4-cyano-2,6-dimethylphenoxy substituent at position 4 and having a 4-cyanophenyl substituent attached to the 2-amino group. NNRTI of HIV-1, binds directly to RT and blocks RNA-dependent and DNA-dependent DNA polymerase activities | etravirine |
tetrachloroisophthalonitrile | A dinitrile that is benzene-1,3-dicarbonitrile substituted by four chloro groups. A non-systemic fungicide first introduced in the 1960s, it is used to control a range of diseases in a wide variety of crops. | chlorothalonil |
u 0126 | An aryl sulfide that is (2Z,3Z)-bis[amino(sulfanyl)methylidene]butanedinitrile in which the sulfanyl hydrogens are replaced by 2-aminophenyl groups. An inhibitor of mitogen-activated protein kinase that also exhibits anti-cancer properties. | U0126 |
Research
Studies (4,579)
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
---|---|---|
pre-1990 | 87 (1.90) | 18.7374 |
1990's | 74 (1.62) | 18.2507 |
2000's | 1,689 (36.89) | 29.6817 |
2010's | 2,255 (49.25) | 24.3611 |
2020's | 474 (10.35) | 2.80 |
Study Types
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
---|---|---|
Trials | 102 (2.18%) | 5.53% |
Reviews | 114 (2.44%) | 6.00% |
Case Studies | 43 (0.92%) | 4.05% |
Observational | 11 (0.24%) | 0.25% |
Other | 4,403 (94.22%) | 84.16% |