Acute Disseminated Encephalomyelitis

An acute or subacute inflammatory process of the CENTRAL NERVOUS SYSTEM characterized histologically by multiple foci of perivascular demyelination. Symptom onset usually occurs several days after an acute viral infection or immunization, but it may coincide with the onset of infection or rarely no antecedent event can be identified. Clinical manifestations include CONFUSION, somnolence, FEVER, nuchal rigidity, and involuntary movements. The illness may progress to COMA and eventually be fatal. (Adams et al., Principles of Neurology, 6th ed, p921)

Synonym
Vaccination Encephalitis
Post-Vaccinal Encephalitis
Disseminated Encephalomyelitis, Acute
Encephalomyelitis, Postexanthem
Encephalomyelitis, Postinfectious
Encephalitis, Post-Vaccinal
Encephalitis, Postvaccinal
Acute Disseminated Encephalomyelitis
Post-Vaccinal Encephalomyelitis
Postvaccinal Encephalitis
Postexanthem Encephalomyelitis
Encephalitis, Vaccination
Encephalomyelitis, Acute Disseminated
Postinfectious Encephalomyelitis

Excerpt	Reference
"Acute disseminated encephalomyelitis is a rare central nervous system demyelinating disease that occurs most frequently in children."	( Bresolin, AU; Lignani, L; Marotto, PC; Seguro, AC; Sztajnbok, J, 1998)
"Acute disseminated encephalomyelitis is a demyelinating syndrome that occurs infrequently in children."	( Harel, L; Karmazyn, B; Schonfeld, T; Straussberg, R; Weitz, R, 2001)
"Acute disseminated encephalomyelitis is an immune-mediated demyelinating disorder usually encountered in children or adolescents and characterized by multifocal neurologic deficits of rapid onset."	( Büyükavci, M; Kiliçaslan, B; Onbaş, O; Tan, H, 2004)
"Acute disseminated encephalomyelitis is reported in a 14-year-old male patient associated with a pleural empyema caused by an esophageal perforation."	( Chatterjee, A; Knapp, HK; Larsen, PD; Varilek, BZ; Wright, RR, 2004)
"Acute disseminated encephalomyelitis is an acute demyelinating disorder of the central nervous system that usually occurs in children and young adults."	( Carstairs, KL; Carstairs, SD, 2007)
"Acute disseminated encephalomyelitis is an acute inflammatory demyelinating disorder of the cenrtral nervous system and patients usually present with signs of meningitis, depressed levels of consciousness, disorientation and/or motor or sensory deficits, depending on the affected sites."	( Hayashi, T; Ishii, N; Morozumi, M; Ono, R; Terao, T; Yamada, T; Yoshinaga, A, 2007)
"Acute disseminated encephalomyelitis is an uncommon inflammatory demyelinating disease of the central nervous system."	( Feld, RJ; Nairn, SJ; Ranasuriya, DG, 2008)
"Acute disseminated encephalomyelitis is a rare inflammatory demyelinating disorder often preceded by infection or vaccination."	( Barsi, P; Liptai, Z; Mihály, I; Rudas, G; Ujhelyi, E, 2009)
"Acute disseminated encephalomyelitis is typically a monophasic, postinfectious, demyelinating disease that presents most often with encephalopathy and acute or subacute, multifocal neurologic deficits."	( Abramo, TJ; Arnold, DH; Pittard, A, 2009)
"Acute disseminated encephalomyelitis is characterized by multifocal demyelinating lesions resulting in varied neurological signs."	( Abdallah, RB; Aloulou, H; Chabchoub, I; Daoud, E; Hachicha, M; Kammoun, F; Mahfoudh, A; Mahfoudh, KB; Mnif, J; Mnif, Z; Neji, H; Toumi, N, 2011)
"Acute disseminated encephalomyelitis is an immune-mediated inflammatory disorder of the central nervous system, characterized by demyelination."	( Alehan, F; Demir, S; Erol, I; Ozkale, M; Ozkale, Y, 2012)
"Acute disseminated encephalomyelitis is an acute demyelinating disorder of the central nervous system, which principally affects the brain and spinal cord."	( Aksoy, A; Oguz, M; Ozkan, M; Tanir, G; Yıldız, YT, 2013)
"Acute disseminated encephalomyelitis is an immune-mediated disease that produces multiple inflammatory lesions in the brain and spinal cord."	( Alehan, F; Alkan, O; Erol, I; Ozkale, Y, 2013)
"One definition of acute disseminated encephalomyelitis is "an initial clinical event with a presumed inflammatory and demyelinating cause, with acute or sub-acute onset affecting multifocal areas of the central nervous system"."	( Bir, LS; Degirmenci, E; Erdogan, C; Oguzhanoglu, A, 2013)
"Acute disseminated encephalomyelitis is an inflammatory demyelinating disease of the central nervous system that usually occurs following an antecedent infection or vaccination."	( Amirkashani, D; Ashrafi, MR; Hirbod-Mobarakeh, A; Manafi, F; Rezaei, N; Tavassoli, A; Yaghmaei, B, 2013)
"Acute disseminated encephalomyelitis is an inflammatory demyelinating disease of the central nervous system that has been associated with influenza immunization, but only a few cases related to vaccination for influenza have been reported."	( Chen, WT; Huang, YC; Lin, KP; Peng, MC; Wang, MC, 2016)
"Acute disseminated encephalomyelitis is generally preceded by an infection, and it is usually self-limiting and non-recurrent."	( Burbano, M; Guerra, JC; Ledesma, PA; Pedroza, LA; Procel, P, 2019)

Excerpt	Reference
"We describe a patient with acute disseminated encephalomyelitis (ADEM) who was treated with high-dose intravenous methylprednisolone 2 days after onset of neurologic symptoms."	( Chofflon, M; Delavelle, J; Straub, J, 1997)
"We report a 16-month-old boy with acute disseminated encephalomyelitis (ADEM) who had an early relapse despite prompt treatment with high dose methylprednisolone."	( Anlar, B; Apak, RA; Saatci, I, 1999)
"He was diagnosed as having acute disseminated encephalomyelitis, and thus the oral administration of phenytoin and steroid pulse therapy were begun."	( Oda, Y; Yoshikawa, H, 1999)
"A three year-old boy with severe acute disseminated encephalomyelitis (ADEM) responding dramatically to treatment with intravenous immunoglobulin (IVIG) 1 g/kg/day is described."	( Andersen, JB; Herning, GM; Paerregaard, A; Pedersen, SA, 2000)
"Diagnoses of acute disseminated encephalomyelitis and transverse myelitis with acute motor axonal neuropathy were made, respectively, and steroid pulse therapy and intravenous gamma globulin therapy alleviated the patients' symptoms."	( Itoh, Y; Katoh, H; Koga, H; Nakamura, N; Nokura, K; Osawa, H; Ozeki, T; Tachi, M; Terada, M; Yamamoto, H; Zettsu, T, 2003)
"The diagnosis of acute disseminated encephalomyelitis (ADEM) was made and steroid pulse therapy was started, which resulted in remission of the symptoms without recurrence in the following months."	( Hatsumi, N; Hoshino, T; Miyawaki, S; Sakura, T; Sakurai, A; Takada, S, 2008)
"Diagnosis of acute disseminated encephalomyelitis (ADEM) as a complication of falciparum malaria was made based on sudden onset of neurological events, MRI findings and prompt response to corticosteroid therapy."	( Birakishore, R; Mrutunjaya, D; Rachita, S; Satyasundar, M, 2013)
"Herein, we report an infant with acute disseminated encephalomyelitis, who mimicked the symptoms of meningoencephalitis and the correct diagnosis and treatment were delayed till the development of a severe phase of the disease."	( Amirkashani, D; Ashrafi, MR; Hirbod-Mobarakeh, A; Manafi, F; Rezaei, N; Tavassoli, A; Yaghmaei, B, 2013)
"The patient was diagnosed with acute disseminated encephalomyelitis and treated with methylprednisolone pulse therapy."	( Abe, S; Igarashi, A; Ikeno, M; Nakahara, E; Nakazawa, M; Okumura, A; Shimizu, T; Takahashi, T; Yamashiro, Y, 2015)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	42 (14.33)	23.3326
1990's	28 (9.56)	12.5806
2000's	105 (35.84)	18.1394
2010's	97 (33.11)	28.8240
2020's	21 (7.17)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	1	0
choline	low	1	0
creatine	low	1	0
cytosine	low	2	0
lactic acid	low	2	0
formaldehyde	low	1	0
iodine	low	1	0
kynurenine	low	1	0
thiamine	low	3	0
phenytoin	low	5	0
amitriptyline	low	1	0
aspirin	low	1	0
azathioprine	low	3	0
carbamazepine	low	1	0
clonidine	low	2	0
diazepam	low	1	0
pentetic acid	low	2	0
diphenhydramine	low	1	0
fluorouracil	low	1	0
guanfacine	low	1	0
haloperidol	low	2	0
hydralazine	low	1	0
isoniazid	low	1	0
khellin	low	1	0
meclofenoxate	low	2	0
pentoxifylline	low	1	0
phenobarbital	low	2	0
piracetam	low	1	0
pirenzepine	low	1	0
procainamide	low	1	0
pyrimethamine	low	1	0
risperidone	low	1	0
sulfadiazine	low	1	0
thiabendazole	low	1	0
prednisolone	low	38	0
sorbitol	low	1	0
prednisone	low	13	0
chloramphenicol	low	4	0
aspartic acid	low	1	0
aminopyrine	low	1	0
levodopa	low	2	0
edetic acid	low	1	0
colchicine	low	1	0
mannitol	low	2	0
cytarabine	low	1	0
valine	low	1	0
tryptophan	low	1	0
methylprednisolone	medium	121	1
thiophenes	low	1	0
thiamine pyrophosphate	low	1	0
quinazolines	low	1	0
erythromycin	low	1	0
vancomycin	low	2	0
digoxigenin	low	1	0
methylprednisolone hemisuccinate	low	2	0
streptomycin	low	2	0
gadolinium	low	7	0
trolamine salicylate	low	3	0
levamisole	low	3	0
bromocriptine	low	1	0
phenyl acetate	low	2	0
4-methoxyamphetamine	low	1	0
transferrin	low	1	0
nicergoline	low	1	0
etoposide	low	1	0
methyldopa	low	1	0
propiconazole	low	1	0
cidofovir anhydrous	low	2	0
oseltamivir	low	2	0
n-acetylaspartic acid	low	1	0
cephalosporin c	low	1	0
fluorodeoxyglucose f18	low	1	0
clarithromycin	low	1	0
gadolinium edta	low	1	0
nicotine	low	1	0
imipenem, anhydrous	low	1	0
cyanates	low	1	0
methotrexate	low	4	0
biotin	low	2	0
organophosphonates	low	2	0
cortisone	low	5	0
erythromycin ethylsuccinate	low	1	0
cocaine	low	1	0
mycophenolic acid	low	1	0
clindamycin	low	1	0
iothalamate meglumine	low	1	0
methyl prednisolonate	low	3	0
myelin basic protein	medium	12	2
bilirubin	low	1	0
morphine	low	1	0
silodosin	low	1	0
aluminum	low	1	0
heroin	low	1	0
pregabalin	low	1	0
cefotaxime	low	1	0
cilastatin	low	1	0
gadolinium dtpa	low	3	0
g(m2) ganglioside	low	2	0
g(m1) ganglioside	low	3	0
alpha-synuclein	low	1	0
meglumine ioxithalamate	low	1	0
ro13-9904	low	3	0
ganglioside, gd1a	low	1	0
galactocerebroside	low	3	0
tetracycline	low	1	0
rolitetracycline	low	1	0
vitamin b 12	low	3	0
cyclosporine	low	1	0
myelin oligodendrocyte glycoprotein (35-55)	low	1	0
exudates	low	1	0
acyclovir	low	14	0
levoleucovorin	low	2	0
folic acid	low	1	0
neopterin	low	1	0
clozapine	low	1	0
ganciclovir	low	2	0
valacyclovir	low	1	0
olanzapine	low	1	0

Protein Targets (1,167)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
5-hydroxytryptamine receptor 2C	0	13	1	15
5-hydroxytryptamine receptor 2A	0	13	1	14
5-hydroxytryptamine receptor 1A	0	19	2	21
5-hydroxytryptamine receptor 1B	0	13	1	14
5-hydroxytryptamine receptor 1D	0	6	1	7
5-hydroxytryptamine receptor 1F	0	6	1	7
5-hydroxytryptamine receptor 2B	0	12	2	14
5-hydroxytryptamine receptor 6	0	2	1	3
Sodium-dependent serotonin transporter	0	11	1	12
Sodium-dependent serotonin transporter	0	8	0	9
5-hydroxytryptamine receptor 7	0	5	1	6
5-hydroxytryptamine receptor 5A	0	2	1	3
5-hydroxytryptamine receptor 5B	0	2	1	3
5-hydroxytryptamine receptor 3A	0	3	1	4
5-hydroxytryptamine receptor 4	0	2	1	3
5-hydroxytryptamine receptor 3B	0	3	1	4
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	13	0	0	13
Chain B, HADH2 protein	13	0	0	13
Chain A, ATP-DEPENDENT DNA HELICASE Q1	4	0	0	4
Chain A, Ferritin light chain	11	0	0	11
Thymidine kinase	0	3	0	3
thioredoxin reductase	26	0	0	26
phosphopantetheinyl transferase	15	0	0	15
GLS protein	20	0	0	20
TDP1 protein	36	0	0	36
Smad3	8	0	0	8
thyroid stimulating hormone receptor	19	0	0	19
EWS/FLI fusion protein	20	0	0	20
arylsulfatase A	21	0	0	21
euchromatic histone-lysine N-methyltransferase 2	36	0	0	36
activating transcription factor 6	10	0	0	10
Histone H2A.x	12	0	0	12
Bloom syndrome protein isoform 1	15	0	0	15
hemoglobin subunit beta	3	0	0	3
atrial natriuretic peptide receptor 1 precursor	6	0	0	6
ubiquitin carboxyl-terminal hydrolase 2 isoform a	7	0	0	7
lamin isoform A-delta10	29	0	0	29
Solute carrier family 22 member 1	0	9	0	16
ATP-binding cassette sub-family C member 3	0	33	0	33
Multidrug resistance-associated protein 4	0	33	0	35
Solute carrier family 22 member 6	0	3	0	5
Bile salt export pump	0	8	0	8
Bile salt export pump	0	46	0	46
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	1	0	2
POU domain, class 2, transcription factor 2	0	0	0	2
Cytochrome P450 2C9	0	12	0	13
Cytochrome P450 2J2	0	7	0	8
Disintegrin and metalloproteinase domain-containing protein 17	4	0	0	4
Purine nucleoside phosphorylase	0	0	2	2
Solute carrier family 22 member 6	0	4	0	8
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	3	0	7
Canalicular multispecific organic anion transporter 1	0	32	0	33
Thymidine kinase	0	2	0	2
Luciferase	12	0	0	12
interleukin 8	7	0	0	7
15-lipoxygenase, partial	7	0	0	7
RAR-related orphan receptor gamma	24	0	0	24
GLI family zinc finger 3	31	0	0	31
estrogen receptor 2 (ER beta)	15	0	0	15
nuclear receptor subfamily 1, group I, member 3	22	0	0	22
cytochrome P450 family 3 subfamily A polypeptide 4	22	0	0	22
retinoic acid nuclear receptor alpha variant 1	25	0	0	25
retinoid X nuclear receptor alpha	16	0	0	16
estrogen-related nuclear receptor alpha	31	0	0	31
pregnane X nuclear receptor	21	0	0	21
estrogen nuclear receptor alpha	46	0	0	46
G	10	0	0	10
peroxisome proliferator-activated receptor delta	16	0	0	16
vitamin D (1,25- dihydroxyvitamin D3) receptor	20	0	0	20
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	18	0	0	18
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	8	0	0	8
v-jun sarcoma virus 17 oncogene homolog (avian)	15	0	0	15
chromobox protein homolog 1	22	0	0	22
thyroid hormone receptor beta isoform a	9	0	0	9
thyroid hormone receptor beta isoform 2	25	0	0	25
histone deacetylase 9 isoform 3	3	0	0	3
nuclear factor erythroid 2-related factor 2 isoform 1	25	0	0	25
geminin	36	0	0	36
Voltage-dependent calcium channel gamma-2 subunit	20	0	0	20
Interferon beta	14	0	0	14
HLA class I histocompatibility antigen, B alpha chain	10	0	0	10
Glutamate receptor 2	20	1	0	21
Nicotinate phosphoribosyltransferase	0	2	0	2
Inositol hexakisphosphate kinase 1	10	0	0	10
cytochrome P450 2C9, partial	10	0	0	10
ORF73	0	0	2	2
USP1 protein, partial	12	0	0	12
NFKB1 protein, partial	6	0	0	6
cytochrome P450 2D6	14	0	0	14
cytochrome P450 2D6 isoform 1	15	0	0	15
D(1A) dopamine receptor	8	0	0	8
atrial natriuretic peptide receptor 2 precursor	4	0	0	4
serine/threonine-protein kinase mTOR isoform 1	7	0	0	7
muscarinic acetylcholine receptor M1	19	0	0	19
Polyunsaturated fatty acid lipoxygenase ALOX15B	7	0	0	7
Voltage-dependent L-type calcium channel subunit alpha-1F	0	8	0	8
5-hydroxytryptamine receptor 4	0	18	0	18
Albumin	0	0	6	6
High affinity nerve growth factor receptor	0	1	2	3
Aldo-keto reductase family 1 member B1	0	10	0	10
Muscarinic acetylcholine receptor M2	0	14	1	15
Muscarinic acetylcholine receptor M4	0	14	1	15
Muscarinic acetylcholine receptor M1	0	10	0	10
Muscarinic acetylcholine receptor M3	0	9	0	9
Muscarinic acetylcholine receptor M4	0	10	0	10
Muscarinic acetylcholine receptor M5	0	9	0	9
Muscarinic acetylcholine receptor M5	0	13	0	13
Alpha-2A adrenergic receptor	0	17	2	19
Muscarinic acetylcholine receptor M2	0	9	0	9
Muscarinic acetylcholine receptor M1	0	14	3	18
Angiotensin-converting enzyme	0	12	0	12
D(2) dopamine receptor	0	12	2	19
Alpha-2B adrenergic receptor	0	16	1	17
Alpha-2C adrenergic receptor	0	16	1	17
Muscarinic acetylcholine receptor M3	0	13	1	14
D(1A) dopamine receptor	0	12	0	14
D(1B) dopamine receptor	0	4	0	6
UDP-glucuronosyltransferase 1A4	0	0	0	4
Sodium-dependent noradrenaline transporter	0	15	0	15
Histamine H2 receptor	0	8	0	8
Alpha-1D adrenergic receptor	0	16	1	17
5-hydroxytryptamine receptor 2A	0	16	1	19
5-hydroxytryptamine receptor 2C	0	18	2	20
Histamine H1 receptor	0	5	0	5
Histamine H1 receptor	0	12	3	17
D(3) dopamine receptor	0	12	1	17
Sodium channel protein type 1 subunit alpha	0	4	0	4
Sodium channel protein type 4 subunit alpha	0	4	0	6
UDP-glucuronosyltransferase 1A3	0	0	0	2
5-hydroxytryptamine receptor 2B	0	16	1	17
Alpha-1A adrenergic receptor	0	11	2	13
Histamine H2 receptor	11	1	0	15
D(1A) dopamine receptor	4	1	0	5
5-hydroxytryptamine receptor 6	0	10	0	11
5-hydroxytryptamine receptor 7	0	4	0	4
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Sodium channel protein type 7 subunit alpha	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	8	0	8
Sodium-dependent dopamine transporter	0	5	0	5
Potassium voltage-gated channel subfamily H member 2	0	24	0	24
Voltage-dependent L-type calcium channel subunit alpha-1S	0	8	0	8
Voltage-dependent L-type calcium channel subunit alpha-1C	0	9	0	9
Sodium channel protein type 5 subunit alpha	0	6	0	6
Sodium channel protein type 9 subunit alpha	0	5	0	5
Sigma non-opioid intracellular receptor 1	0	2	1	3
Nuclear receptor subfamily 3 group C member 3	0	11	0	11
Sodium channel protein type 2 subunit alpha	0	4	0	4
Ataxin-2	22	0	0	22
Sigma non-opioid intracellular receptor 1	0	8	1	9
Sodium channel protein type 3 subunit alpha	0	4	0	4
Sodium channel protein type 11 subunit alpha	0	2	0	2
Sodium channel protein type 8 subunit alpha	0	2	0	2
Histamine H3 receptor	0	3	0	3
Sodium channel protein type 10 subunit alpha	0	2	0	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	19	0	0	19
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	16	0	0	16
aldehyde dehydrogenase 1 family, member A1	20	0	0	20
cytochrome P450 2C19 precursor	11	0	0	11
lethal factor (plasmid)	10	0	0	10
Metabotropic glutamate receptor 6	0	0	1	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate transporter homolog	0	0	1	1
Carbonic anhydrase 1	0	5	0	8
Carbonic anhydrase 2	0	5	1	9
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	0	0	1
Glutamate receptor ionotropic, NMDA 1	0	3	0	6
Excitatory amino acid transporter 1	0	1	0	1
Excitatory amino acid transporter 2	0	1	0	1
Excitatory amino acid transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	3	0	6
Glutamate receptor ionotropic, NMDA 2B	0	3	0	6
Glutamate receptor ionotropic, NMDA 2C	0	3	0	6
Metabotropic glutamate receptor 1	0	0	1	1
Metabotropic glutamate receptor 2	0	0	1	1
Carbonic anhydrase-like protein, putative	0	0	0	3
Glutamate receptor ionotropic, NMDA 2D	0	3	0	6
Glutamate receptor ionotropic, NMDA 3B	0	3	0	6
Carbonic anhydrase 4	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	3	0	6
Chain A, Phospholipase A2 isoform 3	0	0	1	1
Chain A, 2-oxoglutarate Oxygenase	14	0	0	14
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
AR protein	39	0	0	39
hypothetical protein, conserved	3	0	0	3
glucocorticoid receptor [Homo sapiens]	25	0	0	25
glucocerebrosidase	5	0	0	5
Rac1 protein	0	0	1	1
IDH1	13	0	0	13
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	6	0	0	6
DNA polymerase iota isoform a (long)	14	0	0	14
DNA polymerase kappa isoform 1	7	0	0	7
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Epidermal growth factor receptor	0	6	0	6
Fatty acid-binding protein, liver	0	3	0	3
Integrin beta-3	6	1	0	7
Myeloperoxidase	0	4	0	4
Prostaglandin G/H synthase 1	0	1	0	1
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	6	1	0	7
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Adenosine receptor A1	0	4	0	5
Adenosine receptor A2a	0	1	1	3
Substance-P receptor	0	2	0	2
Prostaglandin G/H synthase 2	0	3	0	3
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Nuclear receptor ROR-gamma	7	0	0	7
Ras-related protein Rab-2A	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	16	7	2	25
Prostaglandin G/H synthase 2	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	3	1	4
acetylcholinesterase	13	0	0	13
SMAD family member 2	6	0	0	6
ATAD5 protein, partial	15	0	0	15
Fumarate hydratase	8	0	0	8
SMAD family member 3	6	0	0	6
Microtubule-associated protein tau	11	0	0	11
thioredoxin glutathione reductase	5	0	0	5
farnesoid X nuclear receptor	11	0	0	11
polyprotein	8	0	0	8
P53	2	0	0	2
peroxisome proliferator activated receptor gamma	16	0	0	16
aryl hydrocarbon receptor	15	0	0	15
thyroid stimulating hormone receptor	8	0	0	8
peripheral myelin protein 22 isoform 1	11	0	0	11
cellular tumor antigen p53 isoform a	8	0	0	8
heat shock protein beta-1	4	0	0	4
peripheral myelin protein 22	19	0	0	19
survival motor neuron protein isoform d	14	0	0	14
cytochrome P450 3A4 isoform 1	16	0	0	16
M-phase phosphoprotein 8	10	0	0	10
muscleblind-like protein 1 isoform 1	7	0	0	7
Gamma-aminobutyric acid receptor subunit pi	16	6	1	23
Cellular tumor antigen p53	24	0	0	24
Gamma-aminobutyric acid receptor subunit beta-1	16	6	1	23
Gamma-aminobutyric acid receptor subunit delta	16	6	1	23
Gamma-aminobutyric acid receptor subunit gamma-2	16	6	2	24
Gamma-aminobutyric acid receptor subunit alpha-5	16	6	1	23
Gamma-aminobutyric acid receptor subunit alpha-3	16	6	1	23
Gamma-aminobutyric acid receptor subunit gamma-1	16	6	1	23
Gamma-aminobutyric acid receptor subunit alpha-2	16	6	1	23
Gamma-aminobutyric acid receptor subunit alpha-4	16	6	1	23
Gamma-aminobutyric acid receptor subunit gamma-3	16	6	1	23
Gamma-aminobutyric acid receptor subunit alpha-6	16	6	1	23
Gamma-aminobutyric acid receptor subunit beta-3	16	6	1	23
Gamma-aminobutyric acid receptor subunit beta-2	16	6	2	24
GABA theta subunit	16	6	1	23
ATPase family AAA domain-containing protein 5	16	0	0	16
Gamma-aminobutyric acid receptor subunit epsilon	16	6	1	23
Protein-arginine deiminase type-4	0	6	0	6
pregnane X receptor	8	0	0	8
progesterone receptor	17	0	0	17
nuclear receptor subfamily 1, group I, member 2	4	0	0	4
nuclear factor erythroid 2-related factor 2 isoform 2	16	0	0	16
galanin receptor type 3	0	1	0	1
Glucocorticoid receptor	0	10	2	17
Glycine receptor subunit alpha-1	0	10	0	10
Glycine receptor subunit beta	0	10	0	10
Glycine receptor subunit alpha-2	0	10	0	10
Glycine receptor subunit alpha-3	0	10	0	10
Chain A, Putative fructose-1,6-bisphosphate aldolase	7	0	0	7
Chain A, Cruzipain	2	0	0	2
vitamin D3 receptor isoform VDRA	12	0	0	12
caspase-1 isoform alpha precursor	3	0	0	3
Caspase-7	2	0	0	2
Inositol monophosphatase 1	9	0	0	9
Solute carrier organic anion transporter family member 1B3	0	9	0	11
Solute carrier organic anion transporter family member 1B1	0	5	0	6
Chain A, Avidin	0	0	1	1
Chain A, Protein (streptavidin)	0	0	1	1
Chain B, Protein (streptavidin)	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin Complex With Biotin	0	0	1	1
Chain D, Circularly Permuted Core-streptavidin E51/a46	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	7	0	0	7
apical membrane antigen 1, AMA1	4	0	0	4
nonstructural protein 1	0	2	0	2
green fluorescent protein, partial	0	1	0	1
insulin-degrading enzyme isoform 1	0	0	1	1
Streptavidin	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
Genome polyprotein	0	1	1	2
dopamine D1 receptor	8	0	0	8
regulator of G-protein signaling 4	12	0	0	12
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	9	0	0	9
ATP-dependent translocase ABCB1	0	6	0	6
ATP-dependent translocase ABCB1	0	12	0	20
Beta-1 adrenergic receptor	0	2	0	2
Cytochrome P450 3A4	0	16	1	19
5-hydroxytryptamine receptor 1A	0	8	3	11
Androgen receptor	0	5	0	5
D	0	9	0	9
D(3) dopamine receptor	0	8	0	8
Alpha-2B adrenergic receptor	0	10	1	11
ATP-dependent translocase ABCB1	0	6	0	6
Alpha-2C adrenergic receptor	0	10	1	11
Alpha-2A adrenergic receptor	0	10	1	11
D(1B) dopamine receptor	0	6	0	6
D(4) dopamine receptor	0	7	0	7
Alpha-synuclein	2	2	0	4
D(2) dopamine receptor	0	11	1	12
ATP-dependent phosphofructokinase	17	0	0	17
Chain A, Beta-lactamase	8	0	0	8
mitogen-activated protein kinase 1	8	0	0	8
Vpr	3	0	0	3
Major prion protein	0	0	2	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	3
Cytochrome P450 2B6	0	0	1	1
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	1	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase type 2	0	0	0	2
Metallo-beta-lactamase VIM-11	0	0	0	2
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	1	0	2
Metallo-beta-lactamase VIM-19	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	1	0	2
Albumin	0	0	4	5
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	2
Beta-lactamase	0	0	0	2
Kappa-type opioid receptor	0	3	0	5
Solute carrier family 15 member 1	0	5	0	6
B2 metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Solute carrier family 15 member 2	0	1	0	1
Metallo-beta-lactamase VIM-13	0	1	0	3
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase Toho-1	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 7	0	1	0	1
Metallo-beta-lactamase	0	0	0	2
Solute carrier family 15 member 2	0	2	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
Metallo-b-lactamase	0	0	0	2
BlaVIM-1	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	2
Histamine H3 receptor	0	0	0	3
Beta-lactamase class B VIM-2	0	0	0	2
Solute carrier family 22 member 11	0	1	0	3
Solute carrier family 22 member 8	0	2	0	2
Beta-lactamase VIM-1	0	1	0	3
Solute carrier family 22 member 7	0	1	0	2
streptokinase A precursor	0	0	5	5
Dihydroxyacetone phosphate acyltransferase	0	0	0	2
30S ribosomal protein S6	0	3	1	4
30S ribosomal protein S7	0	3	1	4
50S ribosomal protein L15	0	3	1	4
50S ribosomal protein L10	0	3	1	4
50S ribosomal protein L11	0	3	1	4
50S ribosomal protein L7/L12	0	3	1	4
50S ribosomal protein L19	0	3	1	4
50S ribosomal protein L1	0	3	1	4
50S ribosomal protein L20	0	3	1	4
50S ribosomal protein L27	0	3	1	4
50S ribosomal protein L28	0	3	1	4
50S ribosomal protein L29	0	3	1	4
50S ribosomal protein L31	0	3	1	4
50S ribosomal protein L31 type B	0	3	1	4
50S ribosomal protein L32	0	3	1	4
50S ribosomal protein L33	0	3	1	4
50S ribosomal protein L34	0	3	1	4
50S ribosomal protein L35	0	3	1	4
50S ribosomal protein L36	0	3	1	4
30S ribosomal protein S10	0	3	1	4
30S ribosomal protein S11	0	3	1	4
30S ribosomal protein S12	0	3	1	4
30S ribosomal protein S13	0	3	1	4
30S ribosomal protein S16	0	3	1	4
30S ribosomal protein S18	0	3	1	4
30S ribosomal protein S19	0	3	1	4
30S ribosomal protein S20	0	3	1	4
30S ribosomal protein S2	0	3	1	4
30S ribosomal protein S3	0	3	1	4
30S ribosomal protein S4	0	3	1	4
30S ribosomal protein S5	0	3	1	4
30S ribosomal protein S8	0	3	1	4
30S ribosomal protein S9	0	3	1	4
50S ribosomal protein L13	0	3	1	4
50S ribosomal protein L14	0	3	1	4
50S ribosomal protein L16	0	3	1	4
50S ribosomal protein L23	0	3	1	4
30S ribosomal protein S15	0	3	1	4
50S ribosomal protein L17	0	3	1	4
50S ribosomal protein L21	0	3	1	4
50S ribosomal protein L30	0	3	1	4
50S ribosomal protein L6	0	3	1	4
30S ribosomal protein S14	0	3	1	4
30S ribosomal protein S17	0	3	1	4
30S ribosomal protein S1	0	3	1	4
50S ribosomal protein L18	0	3	1	4
50S ribosomal protein L2	0	3	1	4
50S ribosomal protein L3	0	3	1	4
50S ribosomal protein L24	0	3	1	4
50S ribosomal protein L4	0	3	1	4
50S ribosomal protein L22	0	3	1	4
50S ribosomal protein L5	0	3	1	4
30S ribosomal protein S21	0	3	1	4
50S ribosomal protein L25	0	3	1	4
50S ribosomal protein L36 2	0	3	1	4
Methionine--tRNA ligase, mitochondrial	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	3	0	4
Solute carrier family 22 member 2	0	3	0	4
Solute carrier family 22 member 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-4	0	4	2	7
Neuronal acetylcholine receptor subunit alpha-2	0	3	2	6
Neuronal acetylcholine receptor subunit beta-2	0	4	2	7
Neuronal acetylcholine receptor subunit beta-3	0	3	2	6
Neuronal acetylcholine receptor subunit beta-4	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-5	0	3	2	6
Acetylcholinesterase	0	4	0	4
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-9	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-7	0	4	2	7
Solute carrier family 22 member 1	0	7	0	8
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	3	2	6
Solute carrier family 22 member 2	0	6	0	7
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Thymidine kinase	0	0	0	1
Beta-2 adrenergic receptor	0	5	0	5
Beta-1 adrenergic receptor	0	4	0	4
Dipeptidase 1	0	1	0	1
Beta-3 adrenergic receptor	0	3	0	3
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
General amino-acid permease GAP1	0	0	0	1
Nitric oxide synthase, brain	0	1	0	1
Nitric oxide synthase, brain	0	1	0	1
importin subunit beta-1 isoform 1	6	0	0	6
snurportin-1	6	0	0	6
GTP-binding nuclear protein Ran isoform 1	3	0	0	3
urokinase-type plasminogen activator precursor	7	0	0	7
plasminogen precursor	7	0	0	7
urokinase plasminogen activator surface receptor precursor	7	0	0	7
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	9	0	0	9
Beta-1 adrenergic receptor	0	1	1	2
Alpha-1B adrenergic receptor	0	0	1	1
cytochrome P450 2C9 precursor	6	0	0	6
Membrane primary amine oxidase	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	1	2
Solute carrier family 22 member 3	0	5	0	5
Alpha-1B adrenergic receptor	0	10	1	11
Alpha-1A adrenergic receptor	0	0	1	1
Amine oxidase [flavin-containing] A	0	1	0	1
Alpha-1D adrenergic receptor	0	9	1	10
Amine oxidase [flavin-containing] B	0	1	0	1
Adenosine receptor A2b	0	0	1	1
Alpha-2B adrenergic receptor	0	0	0	1
Delta-type opioid receptor	0	3	0	4
Alpha-1A adrenergic receptor	0	8	1	9
Alpha-1B adrenergic receptor	0	7	1	8
Spike glycoprotein	12	0	0	12
Mu-type opioid receptor	0	4	0	4
Alpha-2C adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Nischarin	0	2	0	2
Multidrug and toxin extrusion protein 1	0	6	0	6
Nischarin	0	2	0	2
5-hydroxytryptamine receptor 3E	0	3	0	3
hypoxia-inducible factor 1 alpha subunit	9	0	0	9
caspase 7, apoptosis-related cysteine protease	4	0	0	4
bromodomain adjacent to zinc finger domain 2B	6	0	0	6
caspase-3	4	0	0	4
Adenylate cyclase type 1	0	2	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	12	0	0	12
DNA polymerase beta	4	0	0	4
nuclear receptor ROR-gamma isoform 1	9	0	0	9
short transient receptor potential channel 6 isoform 1	0	0	1	1
transient receptor potential cation channel subfamily V member 1	2	0	0	2
5-hydroxytryptamine receptor 3B	0	3	0	3
Calmodulin-1	0	1	0	1
Cytochrome P450 2D6	0	3	0	4
D(2) dopamine receptor	0	4	0	4
Endothelin receptor type B	1	1	0	2
D(4) dopamine receptor	0	7	1	12
Adenylate cyclase type 3	0	2	0	2
Sodium-dependent dopamine transporter	0	6	0	6
5-hydroxytryptamine receptor 3A	0	2	0	2
Endothelin receptor type B	0	1	0	1
Adenylate cyclase type 2	0	2	0	2
Adenylate cyclase type 4	0	2	0	2
Histamine H1 receptor	0	3	1	5
Cytochrome P450 2C19	0	2	0	3
5-hydroxytryptamine receptor 2C	0	3	0	3
5-hydroxytryptamine receptor 7	0	4	0	4
5-hydroxytryptamine receptor 2A	0	3	0	3
Adenylate cyclase type 8	0	2	0	2
5-hydroxytryptamine receptor 3A	0	3	0	3
5-hydroxytryptamine receptor 5A	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	3	0	3
D(2) dopamine receptor	0	2	0	2
D(3) dopamine receptor	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	2	0	2
D(2) dopamine receptor	0	2	0	2
Calmodulin	0	0	1	1
5-hydroxytryptamine receptor 2B	0	3	0	3
Adenylate cyclase type 6	0	2	0	2
Adenylate cyclase type 5	0	2	0	2
5-hydroxytryptamine receptor 4	0	2	0	2
Transporter	0	4	0	4
Cholecystokinin receptor type A	0	2	0	2
5-hydroxytryptamine receptor 1A	0	2	0	2
5-hydroxytryptamine receptor 3D	0	3	0	3
Adenylyl cyclase 7	0	2	0	2
5-hydroxytryptamine receptor 3C	0	3	0	3
D	0	3	0	3
Histamine H4 receptor	0	2	1	3
Transporter	0	7	1	9
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	5	0	5
Gamma-aminobutyric acid receptor subunit delta	0	5	0	5
Amyloid-beta precursor protein	2	2	0	4
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Tryptophan 5-hydroxylase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	5	3	8
Gamma-aminobutyric acid receptor subunit beta-1	0	5	1	6
Gamma-aminobutyric acid receptor subunit gamma-2	0	5	2	7
Liver carboxylesterase 1	0	0	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	5	2	7
Gamma-aminobutyric acid receptor subunit alpha-5	0	5	3	8
Gamma-aminobutyric acid receptor subunit alpha-3	0	5	2	7
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	5	2	7
Gamma-aminobutyric acid receptor subunit beta-2	0	5	2	7
Gamma-aminobutyric acid receptor subunit alpha-4	0	5	1	6
Gamma-aminobutyric acid receptor subunit epsilon	0	5	0	5
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
Leukotriene B4 receptor 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	5	1	6
Sodium-dependent dopamine transporter	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	5	0	5
Gamma-aminobutyric acid receptor subunit gamma-3	0	5	0	5
Leukotriene B4 receptor 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	5	0	5
endonuclease IV	9	0	0	9
PAX8	0	0	0	2
PPM1D protein	3	0	0	3
Thrombopoietin	6	0	0	6
67.9K protein	11	0	0	11
nuclear receptor subfamily 0 group B member 1	0	1	0	1
flap endonuclease 1	13	0	0	13
ras-related protein Rab-9A	5	0	0	5
steroidogenic factor 1	0	1	0	1
neuropeptide S receptor isoform A	2	0	0	2
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Plasma kallikrein	0	0	0	3
Tubulin beta-4A chain	0	2	2	5
Tubulin beta chain	0	2	2	5
Tubulin alpha-3C chain	0	2	2	5
Serine/threonine-protein kinase pim-1	0	1	0	1
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	3	0	3
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	2	0	2
Similar to alpha-tubulin isoform 1	0	2	0	2
CREB-binding protein	1	0	0	1
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
Sex hormone-binding globulin	0	0	1	1
Corticosteroid-binding globulin	0	2	0	2
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
TAR DNA-binding protein 43	8	1	0	9
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	2	0	2
Carbonic anhydrase 4	0	1	0	3
Carbonic anhydrase 15	0	1	0	3
glp-1 receptor, partial	13	0	0	13
LMP1 [Human herpesvirus 4]	0	0	0	3
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	3	0	3
transactivating tegument protein VP16 [Human herpesvirus 1]	0	3	0	3
nuclear receptor coactivator 3 isoform a	0	3	0	3
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	4	0	5
Thymidine kinase	0	1	0	1
Deoxycytidine kinase	0	0	0	1
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	1	0	2
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
Deoxycytidine kinase	0	0	0	1
Gamma-aminobutyric acid	0	2	1	3
Alpha-1-acid glycoprotein 1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Translocator protein	0	2	2	5
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit delta	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	1	3
Translocator protein	0	1	0	1
Translocator protein	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	1	3
Gamma-aminobutyric acid receptor subunit pi	0	2	1	3
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	1	3
Gamma-aminobutyric acid receptor subunit theta	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	1	3
Chain A, DigA16	0	0	1	1
Chain A, DigA16	0	0	1	1
NPC intracellular cholesterol transporter 1 precursor	4	0	0	4
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	2	0	0	2
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Rap guanine nucleotide exchange factor 4	2	0	0	2
huntingtin isoform 2	3	0	0	3
Histamine N-methyltransferase	0	0	0	1
Calcium release-activated calcium channel protein 1	0	1	0	1
Protein orai-2	0	1	0	1
Protein orai-3	0	1	0	1
Eyes absent homolog 2	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	1
Motilin receptor	0	0	1	1
acid sphingomyelinase	3	0	0	3
low molecular weight phosphotyrosine protein phosphatase isoform c	0	2	0	2
serine/threonine-protein kinase PLK1	1	0	0	1
Motilin receptor	0	1	1	2
Rap guanine nucleotide exchange factor 3	2	0	0	2
60 kDa chaperonin	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	2	0	2
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	2	0	2
10 kDa heat shock protein, mitochondrial	0	2	0	2
Cytochrome P450 1B1	0	2	0	2
Thiosulfate sulfurtransferase	0	2	0	2
Lanosterol 14-alpha demethylase	0	1	0	1
60 kDa chaperonin	0	2	0	2
10 kDa chaperonin	0	2	0	2
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
Prothrombin	0	0	0	1
Regulatory protein E2	0	0	1	1
DNA topoisomerase 1	0	1	0	2
DNA topoisomerase 2-alpha	0	2	1	9
Polyunsaturated fatty acid lipoxygenase ALOX15	0	6	0	6
DNA topoisomerase 2	0	0	0	2
UDP-glucuronosyltransferase 1A1	0	0	0	2
Serum paraoxonase/arylesterase 1	0	1	0	1
Caspase-3	0	1	0	1
DNA topoisomerase 2-alpha	0	0	0	1
DNA topoisomerase 2-beta	0	1	1	9
Integrase	0	4	0	4
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Skn7p	0	0	0	1
nonstructural protein 1	5	0	0	5
Solute carrier family 22 member 8	0	0	0	1
Aromatase	0	1	0	1
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
Chain A, Dihydrofolate reductase	0	0	1	1
alpha-galactosidase	2	0	0	2
lysosomal alpha-glucosidase preproprotein	3	0	0	3
Thymidylate synthase	0	4	0	4
Dihydrofolate reductase	0	4	4	9
Aldo-keto reductase family 1 member B1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Solute carrier organic anion transporter family member 1A3	0	1	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Multidrug resistance associated protein	0	1	0	3
P-selectin	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	2	3
transcriptional regulator ERG isoform 3	6	0	0	6
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
histone acetyltransferase KAT2A isoform 1	11	0	0	11
Histone deacetylase 3	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Histone deacetylase 4	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Histone deacetylase 1	0	1	0	1
Sterol O-acyltransferase 1	0	0	1	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Histone deacetylase 8	0	1	0	1
Platelet glycoprotein VI	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Histone deacetylase 6	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
ClpP	2	0	0	2
Transitional endoplasmic reticulum ATPase	0	1	0	1
POU domain, class 2, transcription factor 1	0	0	0	1
Cocaine esterase	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
UDP-glucuronosyltransferase 1A9	0	1	0	3
Potassium channel subfamily K member 2	0	1	0	1
Vitamin D-binding protein	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Integrin beta-1	0	1	0	1
Integrin alpha-4	0	1	0	1
Carbonyl reductase [NADPH] 1	0	0	0	1
C-8 sterol isomerase	0	1	0	1
Delta-type opioid receptor	0	5	1	7
Mu-type opioid receptor	0	5	1	9
Kappa-type opioid receptor	0	4	1	6
Mu-type opioid receptor	0	4	2	7
5-hydroxytryptamine receptor 2A	0	1	0	1
AP-2 complex subunit sigma	0	1	0	1
N-acetyltransferase Eis	0	2	0	2
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Calcitonin gene-related peptide type 1 receptor	0	1	0	1
Genome polyprotein	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Zinc finger protein 664	0	1	0	1
Vesicular acetylcholine transporter	0	1	0	1
Protease	0	2	0	2
Transient receptor potential cation channel subfamily V member 4	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Parkin	2	0	0	2
pyruvate kinase	5	0	0	5
pyruvate kinase PKM isoform b	2	0	0	2
N-glycosylase/DNA lyase	0	2	0	2
Ornithine decarboxylase	2	0	0	2
Aspartate aminotransferase, cytoplasmic	0	1	0	1
Lactoperoxidase	0	1	0	1
Single-stranded DNA cytosine deaminase	2	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Beta-lactamase TEM	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
Beta-lactamase	0	0	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Polyphenol oxidase 2	0	1	0	2
Cytochrome P450 1A2	0	5	0	5
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Cytochrome P450 2C8	0	1	0	1
Cytochrome P450 2A6	0	3	1	4
Macrophage migration inhibitory factor	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	3
Pantothenate synthetase	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Endonuclease 8-like 1	0	1	0	1
GALC protein	4	0	0	4
Cytochrome P450 1A1	0	2	0	2
Alkaline phosphatase, tissue-nonspecific isozyme	0	3	0	3
Alkaline phosphatase, placental type	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Intestinal-type alkaline phosphatase	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
Phospholipase A-2-activating protein	0	2	0	2
WRN	2	0	0	2
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
DNA polymerase eta isoform 1	4	0	0	4
Carbonic anhydrase 12	0	0	0	2
Tyrosine-protein kinase Lck	0	1	0	1
Tyrosine-protein kinase Fyn	0	3	0	3
Carbonic anhydrase 3	0	0	0	2
Tyrosinase	0	1	0	1
Carbonic anhydrase 6	0	2	0	4
Carbonic anhydrase 5A, mitochondrial	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase 7	0	0	0	2
Carbonic anhydrase	0	0	0	2
Large neutral amino acids transporter small subunit 1	0	3	0	3
SLC16A10 protein	0	0	0	2
Carbonic anhydrase 9	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Monocarboxylate transporter 10	0	0	0	2
Carbonic anhydrase 13	0	0	0	2
Carbonic anhydrase 14	0	0	0	2
Carbonic anhydrase 5B, mitochondrial	0	0	0	2
phosphoglycerate kinase	3	0	0	3
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	6	0	7
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	3	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	0	1	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	3	0	3
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	4	0	4
Histidine decarboxylase	0	1	1	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	0	1	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Multidrug resistance-associated protein 1	0	1	0	2
Reduced folate transporter	0	2	0	2
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Pteridine reductase 1	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	3
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
estrogen receptor beta isoform 1	0	2	0	2
Cystathionine gamma-lyase	0	1	0	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	2	0	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Chain A, Probable serine/threonine-protein kinase pknB	0	1	0	1
DNA polymerase III, partial	1	0	0	1
LANA	0	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
phospholipase A2, group III	0	1	0	1
interferon gamma precursor	0	0	0	1
histone-lysine N-methyltransferase NSD2 isoform 1	0	0	0	1
protein AF-9 isoform a	0	0	0	1
tyrosine-protein kinase Yes	1	0	0	1
dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	0	1
rac GTPase-activating protein 1 isoform a	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Glycoprotein hormones alpha chain	1	0	0	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Proto-oncogene tyrosine-protein kinase ROS	0	1	0	1
Casein kinase II subunit alpha'	0	1	0	1
Guanine nucleotide-binding protein G	3	0	0	3
Casein kinase II subunit beta	0	1	0	1
Casein kinase II subunit alpha	0	1	0	1
Tyrosine-protein kinase BTK	0	1	0	1
NEDD8-activating enzyme E1 regulatory subunit	0	0	1	1
Multidrug and toxin extrusion protein 2	0	2	0	2
Casein kinase II subunit alpha 3	0	1	0	1
NEDD8-activating enzyme E1 catalytic subunit	0	0	1	1
P2Y purinoceptor 12	0	2	0	2
Opioid receptor, delta 1b	0	1	0	1
Acetylcholinesterase	0	2	0	2
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Proteinase-activated receptor 1	0	1	1	2
Kappa-type opioid receptor	0	2	1	4
Delta-type opioid receptor	0	2	1	4
Kappa-type opioid receptor	0	2	1	4
Mu-type opioid receptor	0	2	1	5
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	2	0	2
Glutamate receptor 1	0	1	0	1
Glutamate receptor 3	0	1	0	1
Glutamate receptor 4	0	1	0	1
Inosine-5'-monophosphate dehydrogenase 1	0	2	0	2
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A7	0	0	0	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Acetylcholine receptor subunit beta	0	2	1	3
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Cytochrome P450 2A5	0	1	0	1
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
Neuronal acetylcholine receptor subunit beta-4	0	2	1	3
Muscarinic acetylcholine receptor M4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	4
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Acetylcholine-binding protein	0	1	1	2
Acetylcholine receptor subunit epsilon	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Cytochrome P450 2A13	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	1	0	1
Neuraminidase	0	2	0	2
Sialidase	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	1	0	1
Neuraminidase	0	1	0	1
Sialidase-4	0	1	0	1
Sialidase-1	0	1	0	1
Sialidase-3	0	1	0	1
Sialidase-2	0	1	0	1
vasopressin V1b receptor	1	0	0	1
relaxin receptor 1 isoform 1	1	0	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	2	0	2
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Tumor necrosis factor	0	1	0	1
Cholinesterase	0	1	0	1
Adenosine receptor A2b	0	1	0	1
Chitotriosidase-1	0	2	1	3
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Endochitinase B1	0	2	1	3
Aldo-keto reductase family 1 member B1	0	1	0	1
Synaptic vesicle glycoprotein 2A	0	1	0	1
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Muscarinic acetylcholine receptor	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	1	0	1
Sterol O-acyltransferase 1	0	1	0	1
Acetylcholinesterase	0	1	0	1
DNA (cytosine-5)-methyltransferase 1	0	1	0	1
Sterol O-acyltransferase 1	0	1	0	1
Solute carrier family 22 member 4	0	1	0	1
DNA (cytosine-5)-methyltransferase 3-like	0	1	0	1
DNA (cytosine-5)-methyltransferase 3A	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	2
heat shock protein 90, putative	0	0	0	1
dual specificity protein phosphatase 3	0	1	0	1
tyrosine-protein phosphatase non-receptor type 22 isoform 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Estrogen receptor	0	0	1	1
Beta-hexosaminidase subunit alpha	0	1	0	2
Beta-hexosaminidase subunit beta	0	1	0	1
Substance-K receptor	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Estrogen receptor beta	0	0	1	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Multidrug and toxin extrusion protein 1	0	1	0	1
Glycine receptor subunit alpha-1	0	0	1	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
Insulin-degrading enzyme	0	1	0	1
DNA repair protein RAD52 homolog	0	1	0	1
Alpha-1A adrenergic receptor	0	1	0	1
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Potassium voltage-gated channel subfamily D member 3	0	1	0	1
Aurora kinase A	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
Stromelysin-1	0	2	0	2
Multidrug transporter MdfA	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
BRCA1	1	0	0	1
Methionine aminopeptidase	0	1	0	1
Endothelin-1 receptor	1	0	0	1
Methionine aminopeptidase 2	0	1	0	1
Methionine aminopeptidase 1	0	1	1	2
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
Reverse transcriptase/RNaseH	0	1	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
1-deoxy-D-xylulose-5-phosphate synthase	0	0	1	1
1-deoxy-D-xylulose-5-phosphate synthase	0	0	1	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Indoleamine 2,3-dioxygenase 1	0	1	0	2
Tryptophan 2,3-dioxygenase	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Solute carrier family 15 member 1	0	1	0	1
Valacyclovir hydrolase	0	0	0	1
Chain A, Arginase 1	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Acute Disseminated Encephalomyelitis

Synonyms(14)

Research Excerpts

Overview

Treatment

Research

Studies (293)

Protein Targets (1,167)

Acute Disseminated Encephalomyelitis

Synonyms(14)

Research Excerpts

Overview

Treatment

Research

Studies (293)

Drugs Studied (131)

Protein Targets (1,167)