A terpenoid indole alkaloid which is biosynthesised from L-tryptophan and diisoprenoid (usually secolaganin) building blocks.
Member | Definition | Role |
akuammicine | A monoterpenoid indole alkaloid with formula C20H22N2O2, isolated from several plant species including Alstonia spatulata, Catharanthus roseus and Vinca major. | akuammicine |
brucine | | brucine |
catharanthine | An organic heteropentacyclic compound and monoterpenoid indole alkaloid produced by the medicinal plant Catharanthus roseus via strictosidine. | catharanthine |
coronardine | A monoterpenoid indole alkaloid with formula C21H26N2O2. It is isolated from the flowering plant genus, Tabernaemontana. | (-)-coronaridine |
ervatamine | | Ervatamine |
goniomitine | | Goniomitine |
leuconolam | | Leuconolam |
lundurine a | | Lundurine A |
methyl reserpate | | Methyl reserpate |
mitragynine | | Mitragynine |
noribogaine | An organic heteropentacyclic compound that is ibogamine in which the indole hydrogen para to the indole nitrogen has been replaced by a hydroxy group. It is the primary (and long-lived) metabolite of ibogaine, the psychoactive indole alkaloid found in the African rainforest shrub Tabernanthe iboga. | noribogaine |
pleiocarpamine | | Pleiocarpamine |
quinine | An Aspidosperma alkaloid with molecular formula C21H24N2O3 found in the roots of Madagascar periwinkle (Catharanthus roseus, formerly known as Vinca rosea). | lochnericine |
raubasine | A monoterpenoid indole alkaloid with formula C21H24N2O3, isolated from several Rauvolfia and Catharanthus species. It is a selective alpha1-adrenoceptor antagonist used for the treatment of high blood pressure. | ajmalicine |
stemmadenine | A monoterpenoid indole alkaloid with formula C21H26N2O3, isolated from several plant species including Rhazya stricta, Tabernaemontana dichotoma and Aspidosperma pyricollum. | 15alpha-stemmadenine |
strychnine | A monoterpenoid indole alkaloid that is strychnidine bearing a keto substituent at the 10-position. | strychnine |
strychnine n-oxide | A tertiary amine oxide resulting from the oxidation of the non-acylated nitrogen of strychnine. It is a metabolite of strychnine. | strychnine N-oxide |
tabersonine | A monoterpenoid indole alkaloid with cytotoxic activity. | tabersonine |
vincosamide | | Vincosamide |
vindolinine | A monoterpenoid indole alkaloid with formula C21H24N2O2, isolated from several plant species. | vindolinine |
voacamine | A monoterpenoid indole alkaloid with formula C22H28N2O3, isolated from several plant species. | (-)-voacangine |