immunomodulator

Biologically active substance whose activity affects or plays a role in the functioning of the immune system.

ChEBI ID: 50846

Members (27)

Member	Definition	Class
5-oxo-6,8,11,14-eicosatetraenoic acid	An oxoicosatetraenoic acid having a 5-oxo group; and (6E)-, (8Z), (11Z)- and (14Z)-double bonds.	5-oxo-ETE
alpha-glutamyltryptophan	A dipeptide composed of L-glutamic acid and L-tryptophan joined by a peptide linkage.	Glu-Trp
bigelovin	A sesquiterpene lactone that is 3,3a,4,4a,7a,8,9,9a-octahydroazuleno[6,5-b]furan-2,5-dione substituted by methyl groups at positions 4a and 8, a methylidene group at position 3 and an acetoxy group at position 4. Isolated from Inula hupehensis, it exhibits antineoplastic activity.	bigelovin
birb 796	A member of the class of pyrazoles that is an immunomodulator used for treatment of rheumatoid arthritis, Crohn's disease and psoriasis.	doramapimod
bis(3',5')-cyclic diguanylic acid	A cyclic purine dinucleotide that is the 3',5'-cyclic dimer of MP.	c-di-GMP
caffeic acid phenethyl ester	An alkyl caffeate ester in which 2-phenylethyl is the alkyl component.	phenethyl caffeate
calcitriol	A hydroxycalciol that is calcidiol in which the pro-S hydrogen of calcidiol is replaced by a hydroxy group. It is the active form of vitamin D3, produced fom calciol via hydoxylation in the liver to form calcidiol, which is subsequently oxidised in the kidney to give calcitriol.	calcitriol
curcumin	A beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa.	curcumin
d-alpha tocopherol	An alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils.	(R,R,R)-alpha-tocopherol
dimethyl fumarate	An enoate ester resulting from the formal condensation of both carboxy groups of fumaric acid with methanol. Used for treatment of adults with relapsing forms of multiple sclerosis.	dimethyl fumarate
glycyrrhetinic acid	A pentacyclic triterpenoid that is olean-12-ene substituted by a hydroxy group at position 3, an oxo group at position 11 and a carboxy group at position 30.	glycyrrhetinic acid
hydroxyurea	A member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease.	hydroxyurea
irilone	A hydroxyisoflavone that is 6,7-methylenedioxyisoflavone substituted by hydroxy groups at positions 5 and 4'.	irilone
lenalidomide	A dicarboximide that consists of 1-oxoisoindoline bearing an amino substituent at position 4 and a 2,6-dioxopiperidin-3-yl group at position 2. Inhibits the secretion of TNF-alpha.	lenalidomide
lespenefril	A glycosyloxyflavone that is kaempferol attached to alpha-L-rhamnopyranosyl residues at positions 3 and 7 respectively via glycosidic linkages. It has been isolated from the aerial parts of Vicia faba and Lotus edulis.	kaempferol 3,7-di-O-alpha-L-rhamnoside
levamisole	A 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole that has S configuration. It is used (generally as the monohydrochloride salt) to treat parasitic worm infections in pigs, sheep and cattle and was formerly used in humans as an adjuvant to chemotherapy for the treatment of various cancers. It is also widely used as an adulterant to coccaine.	levamisole
lisofylline	A 1-(5-hydroxyhexyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione that has (R)-configuration. A synthetic small molecule which was under development for the treatment of type 1 diabetes mellitus.	(R)-lisofylline
luteolin	A tetrahydroxyflavone in which the four hydroxy groups are located at positions 3', 4', 5 and 7. It is thought to play an important role in the human body as an antioxidant, a free radical scavenger, an anti-inflammatory agent and an immune system modulator as well as being active against several cancers.	luteolin
miltefosine	A phospholipid that is the hexadecyl monoester of phosphocholine.	miltefosine
monomethyl fumarate	A dicarboxylic acid monoester resulting from the formal condensation of one of the carboxy groups of fumaric acid with methanol. Is is a metabolite of dimethyl fumarate and used for the the treatment of patients with relapsing multiple sclerosis (MS). It also induces the NFE2L2 (Nrf2) transcription factor by binding to KEAP1.	monomethyl fumarate
nicotine	A 3-(1-methylpyrrolidin-2-yl)pyridine in which the chiral centre has S-configuration. The naturally occurring and most active enantiomer of nicotine, isolated from Nicotiana tabacum.	(S)-nicotine
pomalidomide	An aromatic amine that is thalidomide substituted at position 4 on the isoindole ring system by an amino group. Used for the treatment of multiple myeloma in patients who failed to respond to previous therapies.	pomalidomide
salvigenin	A trimethoxyflavone that is scutellarein in which the hydroxy groups at positions 4', 6, and 7 are replaced by methoxy groups.	salvigenin
solasodine	An oxaspiro compound and steroid alkaloid sapogenin with formula C27H43NO2 found in the Solanum (nightshade) family. It is used as a precursor in the synthesis of complex steroidal compounds such as contraceptive pills.	solasodine
su 11248		sunitinib
tepoxalin	A hydroxamic acid obtained by formal condensation of the carboxy group of 3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)pyrazol-3-yl]propanoic acid with the amino group of N-methylhydroxylamine. It is used in veterinary medicine for the control of pain and inflammation caused by musculoskeletal disorders such as hip dysplasia and arthritis in dogs.	tepoxalin
theophylline	A dimethylxanthine having the two methyl groups located at positions 1 and 3. It is structurally similar to caffeine and is found in green and black tea.	theophylline

Research

Studies (134,577)

Timeframe	Studies, Drugs with This Role(%)	All Drugs %
pre-1990	33,336 (24.77)	18.7374
1990's	22,102 (16.42)	18.2507
2000's	27,510 (20.44)	29.6817
2010's	37,771 (28.07)	24.3611
2020's	13,858 (10.30)	2.80

Study Types

Publication Type	Studies, Drugs with this Role (%)	All Drugs (%)
Trials	11,546 (8.10%)	5.53%
Reviews	13,710 (9.61%)	6.00%
Case Studies	5,450 (3.82%)	4.05%
Observational	305 (0.21%)	0.25%
Other	111,613 (78.26%)	84.16%

Protein Targets (1,120)

Potency Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	Homo sapiens (human)	Potency	23.8185	1	5
15-lipoxygenase, partial	Homo sapiens (human)	Potency	6.6072	1	5
67.9K protein	Vaccinia virus	Potency	19.7775	2	5
acetylcholinesterase	Homo sapiens (human)	Potency	59.6689	4	5
activating transcription factor 6	Homo sapiens (human)	Potency	21.1512	2	6
aldehyde dehydrogenase 1 family, member A1	Homo sapiens (human)	Potency	23.8594	1	9
alpha-galactosidase	Homo sapiens (human)	Potency	50.1187	1	1
Alpha-synuclein	Homo sapiens (human)	Potency	11.5110	1	4
apical membrane antigen 1, AMA1	Plasmodium falciparum 3D7	Potency	7.0795	1	1
AR protein	Homo sapiens (human)	Potency	19.6785	10	30
aryl hydrocarbon receptor	Homo sapiens (human)	Potency	32.0381	3	9
arylsulfatase A	Homo sapiens (human)	Potency	24.7114	1	3
ATAD5 protein, partial	Homo sapiens (human)	Potency	16.9061	4	5
Ataxin-2	Homo sapiens (human)	Potency	44.1534	1	2
ATP-dependent phosphofructokinase	Trypanosoma brucei brucei TREU927	Potency	15.1902	4	6
ATPase family AAA domain-containing protein 5	Homo sapiens (human)	Potency	48.3696	2	4
atrial natriuretic peptide receptor 1 precursor	Homo sapiens (human)	Potency	3.0131	1	1
Bloom syndrome protein isoform 1	Homo sapiens (human)	Potency	28.9644	3	8
BRCA1	Homo sapiens (human)	Potency	35.4813	1	1
bromodomain adjacent to zinc finger domain 2B	Homo sapiens (human)	Potency	40.5851	1	3
caspase 7, apoptosis-related cysteine protease	Homo sapiens (human)	Potency	47.6479	1	2
caspase-1 isoform alpha precursor	Homo sapiens (human)	Potency	23.7358	1	2
caspase-3	Homo sapiens (human)	Potency	47.6479	1	2
Caspase-7	Homo sapiens (human)	Potency	12.5893	1	1
Cellular tumor antigen p53	Homo sapiens (human)	Potency	20.8601	3	18
cellular tumor antigen p53 isoform a	Homo sapiens (human)	Potency	20.0770	2	5
Chain A, 2-oxoglutarate Oxygenase	Homo sapiens (human)	Potency	20.9212	1	7
Chain A, ATP-DEPENDENT DNA HELICASE Q1	Homo sapiens (human)	Potency	13.1213	3	6
Chain A, Beta-lactamase	Escherichia coli K-12	Potency	19.9526	1	1
Chain A, Breast cancer type 1 susceptibility protein	Homo sapiens (human)	Potency	5.0119	1	3
Chain A, Cruzipain	Trypanosoma cruzi	Potency	19.1572	1	3
Chain A, Ferritin light chain	Equus caballus (horse)	Potency	18.7548	1	5
Chain A, HADH2 protein	Homo sapiens (human)	Potency	15.2342	2	6
Chain A, JmjC domain-containing histone demethylation protein 3A	Homo sapiens (human)	Potency	71.0754	1	3
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	Homo sapiens (human)	Potency	7.5505	1	6
Chain A, Putative fructose-1,6-bisphosphate aldolase	Giardia intestinalis	Potency	16.7761	1	4
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	Homo sapiens (human)	Potency	20.7739	1	6
Chain B, HADH2 protein	Homo sapiens (human)	Potency	15.2342	2	6
chromobox protein homolog 1	Homo sapiens (human)	Potency	62.0506	1	2
cytochrome P450 2C19 precursor	Homo sapiens (human)	Potency	15.8489	1	1
cytochrome P450 2C9 precursor	Homo sapiens (human)	Potency	31.6228	1	1
cytochrome P450 2C9, partial	Homo sapiens (human)	Potency	6.2628	1	2
cytochrome P450 2D6	Homo sapiens (human)	Potency	19.7021	1	4
cytochrome P450 2D6 isoform 1	Homo sapiens (human)	Potency	31.6228	1	1
cytochrome P450 3A4 isoform 1	Homo sapiens (human)	Potency	20.1221	2	12
cytochrome P450 family 3 subfamily A polypeptide 4	Homo sapiens (human)	Potency	17.7505	1	4
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	Homo sapiens (human)	Potency	34.4925	1	3
D(1A) dopamine receptor	Homo sapiens (human)	Potency	11.2665	2	2
D(1A) dopamine receptor	Sus scrofa (pig)	Potency	0.6561	1	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	Homo sapiens (human)	Potency	14.3484	1	2
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	Homo sapiens (human)	Potency	27.2454	2	3
DNA polymerase beta	Homo sapiens (human)	Potency	25.8740	1	2
DNA polymerase eta isoform 1	Homo sapiens (human)	Potency	23.9154	1	2
DNA polymerase iota isoform a (long)	Homo sapiens (human)	Potency	46.2054	1	4
DNA polymerase kappa isoform 1	Homo sapiens (human)	Potency	20.6508	1	9
dopamine D1 receptor	Homo sapiens (human)	Potency	8.1995	1	1
endonuclease IV	Escherichia coli	Potency	25.1189	1	1
estrogen nuclear receptor alpha	Homo sapiens (human)	Potency	32.0290	8	37
estrogen receptor 2 (ER beta)	Homo sapiens (human)	Potency	22.2616	2	4
estrogen-related nuclear receptor alpha	Homo sapiens (human)	Potency	18.3329	8	24
euchromatic histone-lysine N-methyltransferase 2	Homo sapiens (human)	Potency	12.8583	1	12
EWS/FLI fusion protein	Homo sapiens (human)	Potency	18.0675	4	15
farnesoid X nuclear receptor	Homo sapiens (human)	Potency	31.1398	5	12
flap endonuclease 1	Homo sapiens (human)	Potency	30.3502	1	5
Fumarate hydratase	Homo sapiens (human)	Potency	20.2148	1	3
G	Vesicular stomatitis virus	Potency	6.2628	1	2
GABA theta subunit	Rattus norvegicus (Norway rat)	Potency	20.1221	1	6
galactokinase	Homo sapiens (human)	Potency	47.2690	1	1
GALC protein	Homo sapiens (human)	Potency	0.7079	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	Rattus norvegicus (Norway rat)	Potency	20.1221	1	6
Gamma-aminobutyric acid receptor subunit alpha-2	Rattus norvegicus (Norway rat)	Potency	20.1221	1	6
Gamma-aminobutyric acid receptor subunit alpha-3	Rattus norvegicus (Norway rat)	Potency	20.1221	1	6
Gamma-aminobutyric acid receptor subunit alpha-4	Rattus norvegicus (Norway rat)	Potency	20.1221	1	6
Gamma-aminobutyric acid receptor subunit alpha-5	Rattus norvegicus (Norway rat)	Potency	20.1221	1	6
Gamma-aminobutyric acid receptor subunit alpha-6	Rattus norvegicus (Norway rat)	Potency	20.1221	1	6
Gamma-aminobutyric acid receptor subunit beta-1	Rattus norvegicus (Norway rat)	Potency	20.1221	1	6
Gamma-aminobutyric acid receptor subunit beta-2	Rattus norvegicus (Norway rat)	Potency	20.1221	1	6
Gamma-aminobutyric acid receptor subunit beta-3	Rattus norvegicus (Norway rat)	Potency	20.1221	1	6
Gamma-aminobutyric acid receptor subunit delta	Rattus norvegicus (Norway rat)	Potency	20.1221	1	6
Gamma-aminobutyric acid receptor subunit epsilon	Rattus norvegicus (Norway rat)	Potency	20.1221	1	6
Gamma-aminobutyric acid receptor subunit gamma-1	Rattus norvegicus (Norway rat)	Potency	20.1221	1	6
Gamma-aminobutyric acid receptor subunit gamma-2	Rattus norvegicus (Norway rat)	Potency	20.1221	1	6
Gamma-aminobutyric acid receptor subunit gamma-3	Rattus norvegicus (Norway rat)	Potency	20.1221	1	6
Gamma-aminobutyric acid receptor subunit pi	Rattus norvegicus (Norway rat)	Potency	20.1221	1	6
geminin	Homo sapiens (human)	Potency	11.1194	4	15
GLI family zinc finger 3	Homo sapiens (human)	Potency	24.3984	3	10
glp-1 receptor, partial	Homo sapiens (human)	Potency	11.2202	1	1
GLS protein	Homo sapiens (human)	Potency	19.1688	2	7
glucocerebrosidase	Homo sapiens (human)	Potency	26.4257	1	4
glucocorticoid receptor [Homo sapiens]	Homo sapiens (human)	Potency	32.6712	4	10
Glutamate receptor 2	Rattus norvegicus (Norway rat)	Potency	52.0159	1	2
GTP-binding nuclear protein Ran isoform 1	Homo sapiens (human)	Potency	29.0194	1	3
Guanine nucleotide-binding protein G	Homo sapiens (human)	Potency	23.3507	1	2
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	Homo sapiens (human)	Potency	11.6359	2	8
heat shock protein beta-1	Homo sapiens (human)	Potency	30.5307	2	7
hemoglobin subunit beta	Homo sapiens (human)	Potency	39.8107	1	1
Histamine H2 receptor	Cavia porcellus (domestic guinea pig)	Potency	15.2569	2	13
histone acetyltransferase KAT2A isoform 1	Homo sapiens (human)	Potency	39.8107	1	1
Histone H2A.x	Cricetulus griseus (Chinese hamster)	Potency	70.4330	2	6
histone-lysine N-methyltransferase 2A isoform 2 precursor	Homo sapiens (human)	Potency	42.4600	1	2
HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)	Potency	6.2628	1	2
huntingtin isoform 2	Homo sapiens (human)	Potency	19.5147	1	2
hypoxia-inducible factor 1 alpha subunit	Homo sapiens (human)	Potency	35.1627	2	6
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	Homo sapiens (human)	Potency	3.2900	2	6
IDH1	Homo sapiens (human)	Potency	18.4376	1	3
importin subunit beta-1 isoform 1	Homo sapiens (human)	Potency	30.5094	2	6
Inositol hexakisphosphate kinase 1	Homo sapiens (human)	Potency	6.2628	1	4
Inositol monophosphatase 1	Rattus norvegicus (Norway rat)	Potency	21.4370	1	3
Integrin alpha-IIb	Homo sapiens (human)	Potency	19.1373	1	3
Integrin beta-3	Homo sapiens (human)	Potency	19.1373	1	3
Interferon beta	Homo sapiens (human)	Potency	20.2605	2	11
interleukin 8	Homo sapiens (human)	Potency	65.7173	1	2
lamin isoform A-delta10	Homo sapiens (human)	Potency	7.5911	2	11
lethal factor (plasmid)	Bacillus anthracis str. A2012	Potency	6.7482	1	4
Luciferase	Photinus pyralis (common eastern firefly)	Potency	29.4996	3	7
lysosomal alpha-glucosidase preproprotein	Homo sapiens (human)	Potency	32.3128	1	2
M-phase phosphoprotein 8	Homo sapiens (human)	Potency	38.7482	1	2
Microtubule-associated protein tau	Homo sapiens (human)	Potency	14.3560	2	14
mitogen-activated protein kinase 1	Homo sapiens (human)	Potency	32.1841	2	3
muscleblind-like protein 1 isoform 1	Homo sapiens (human)	Potency	28.7968	1	2
neuropeptide S receptor isoform A	Homo sapiens (human)	Potency	0.3162	1	1
NFKB1 protein, partial	Homo sapiens (human)	Potency	3.1623	2	2
nonstructural protein 1	Influenza A virus (A/WSN/1933(H1N1))	Potency	5.0119	1	1
Nrf2	Homo sapiens (human)	Potency	15.6117	2	3
nuclear factor erythroid 2-related factor 2 isoform 1	Homo sapiens (human)	Potency	33.1223	4	9
nuclear factor erythroid 2-related factor 2 isoform 2	Homo sapiens (human)	Potency	20.5962	1	1
nuclear factor NF-kappa-B p105 subunit isoform 1	Homo sapiens (human)	Potency	50.1187	1	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	Homo sapiens (human)	Potency	14.7184	1	3
Nuclear receptor ROR-gamma	Homo sapiens (human)	Potency	36.3821	1	3
nuclear receptor ROR-gamma isoform 1	Mus musculus (house mouse)	Potency	21.3177	2	20
nuclear receptor subfamily 1, group I, member 3	Homo sapiens (human)	Potency	32.4248	3	11
P53	Homo sapiens (human)	Potency	21.1546	1	2
Parkin	Homo sapiens (human)	Potency	25.7400	2	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Homo sapiens (human)	Potency	57.3911	1	3
peripheral myelin protein 22	Rattus norvegicus (Norway rat)	Potency	7.7185	1	5
peripheral myelin protein 22 isoform 1	Homo sapiens (human)	Potency	42.8439	1	2
peroxisome proliferator activated receptor gamma	Homo sapiens (human)	Potency	23.4296	5	16
peroxisome proliferator-activated receptor delta	Homo sapiens (human)	Potency	23.4154	5	9
phosphoglycerate kinase	Trypanosoma brucei brucei TREU927	Potency	28.1838	1	1
phosphopantetheinyl transferase	Bacillus subtilis	Potency	58.9828	1	7
PINK1	Homo sapiens (human)	Potency	22.3872	1	1
plasminogen precursor	Mus musculus (house mouse)	Potency	5.4320	1	4
polyprotein	Zika virus	Potency	20.2148	1	3
polyunsaturated fatty acid lipoxygenase ALOX12	Homo sapiens (human)	Potency	16.6243	1	4
Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)	Potency	10.3471	1	5
potassium voltage-gated channel subfamily H member 2 isoform d	Homo sapiens (human)	Potency	3.8146	1	2
PPM1D protein	Homo sapiens (human)	Potency	23.3710	1	6
pregnane X nuclear receptor	Homo sapiens (human)	Potency	47.1832	2	6
pregnane X receptor	Rattus norvegicus (Norway rat)	Potency	79.4328	1	1
progesterone receptor	Homo sapiens (human)	Potency	37.5723	2	5
pyruvate kinase PKM isoform a	Homo sapiens (human)	Potency	28.1838	2	2
Rap guanine nucleotide exchange factor 3	Homo sapiens (human)	Potency	24.8401	2	2
RAR-related orphan receptor gamma	Mus musculus (house mouse)	Potency	26.5244	2	6
regulator of G-protein signaling 4	Homo sapiens (human)	Potency	0.9842	1	4
retinoic acid nuclear receptor alpha variant 1	Homo sapiens (human)	Potency	21.2647	3	15
retinoid X nuclear receptor alpha	Homo sapiens (human)	Potency	20.0740	4	14
serine/threonine-protein kinase mTOR isoform 1	Homo sapiens (human)	Potency	4.4043	3	3
serine/threonine-protein kinase PLK1	Homo sapiens (human)	Potency	37.6858	1	1
SMAD family member 2	Homo sapiens (human)	Potency	32.9877	2	5
SMAD family member 3	Homo sapiens (human)	Potency	32.9877	2	5
Smad3	Homo sapiens (human)	Potency	15.0827	1	5
snurportin-1	Homo sapiens (human)	Potency	30.5094	2	6
Spike glycoprotein	Severe acute respiratory syndrome-related coronavirus	Potency	26.9680	1	2
survival motor neuron protein isoform d	Homo sapiens (human)	Potency	14.5983	1	4
TAR DNA-binding protein 43	Homo sapiens (human)	Potency	25.5903	1	4
TDP1 protein	Homo sapiens (human)	Potency	14.1810	2	26
thioredoxin glutathione reductase	Schistosoma mansoni	Potency	39.8107	1	2
thioredoxin reductase	Rattus norvegicus (Norway rat)	Potency	19.8530	3	8
thyroid hormone receptor beta isoform 2	Rattus norvegicus (Norway rat)	Potency	26.9915	3	18
thyroid hormone receptor beta isoform a	Homo sapiens (human)	Potency	50.2657	4	4
thyroid stimulating hormone receptor	Homo sapiens (human)	Potency	25.3694	5	9
thyrotropin-releasing hormone receptor	Homo sapiens (human)	Potency	31.0058	1	2
transcriptional regulator ERG isoform 3	Homo sapiens (human)	Potency	11.4642	1	2
tumor susceptibility gene 101 protein	Homo sapiens (human)	Potency	19.9526	1	1
tyrosine-protein kinase Yes	Homo sapiens (human)	Potency	10.9082	1	2
urokinase plasminogen activator surface receptor precursor	Mus musculus (house mouse)	Potency	5.4320	1	4
urokinase-type plasminogen activator precursor	Mus musculus (house mouse)	Potency	5.4320	1	4
USP1 protein, partial	Homo sapiens (human)	Potency	34.6753	2	10
v-jun sarcoma virus 17 oncogene homolog (avian)	Homo sapiens (human)	Potency	21.7430	2	8
vitamin D (1,25- dihydroxyvitamin D3) receptor	Homo sapiens (human)	Potency	30.5706	5	9
vitamin D3 receptor isoform VDRA	Homo sapiens (human)	Potency	50.4512	1	2
Voltage-dependent calcium channel gamma-2 subunit	Mus musculus (house mouse)	Potency	52.0159	1	2
WRN	Homo sapiens (human)	Potency	6.5201	2	2

Inhibition Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	Homo sapiens (human)	IC50	30.0000	1	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	Homo sapiens (human)	IC50	9.6995	2	2
1-deoxy-D-xylulose 5-phosphate reductoisomerase	Escherichia coli K-12	IC50	3.4000	1	1
10 kDa chaperonin	Escherichia coli	IC50	3.0000	2	2
10 kDa heat shock protein, mitochondrial	Homo sapiens (human)	IC50	8.3000	1	1
17-beta-hydroxysteroid dehydrogenase type 2	Homo sapiens (human)	IC50	1.7300	1	1
3-oxoacyl-acyl-carrier protein reductase	Plasmodium falciparum (malaria parasite P. falciparum)	IC50	4.0000	1	1
3-oxoacyl-acyl-carrier protein reductase	Plasmodium falciparum (malaria parasite P. falciparum)	Ki	1.3000	2	2
5-hydroxytryptamine receptor 1A	Homo sapiens (human)	Ki	86.0000	1	1
5-hydroxytryptamine receptor 3A	Homo sapiens (human)	Ki	71.0000	1	2
5-hydroxytryptamine receptor 3B	Homo sapiens (human)	Ki	71.0000	1	2
5-hydroxytryptamine receptor 3C	Homo sapiens (human)	Ki	71.0000	1	2
5-hydroxytryptamine receptor 3D	Homo sapiens (human)	Ki	71.0000	1	2
5-hydroxytryptamine receptor 3E	Homo sapiens (human)	Ki	71.0000	1	2
5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)	IC50	0.1580	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)	IC50	0.0617	1	1
5'-nucleotidase	Rattus norvegicus (Norway rat)	IC50	20.2000	1	1
60 kDa chaperonin	Escherichia coli K-12	IC50	250.0000	1	1
60 kDa chaperonin	Escherichia coli	IC50	3.0000	2	2
60 kDa heat shock protein, mitochondrial	Homo sapiens (human)	IC50	8.3000	1	1
72 kDa type IV collagenase	Homo sapiens (human)	IC50	3.6100	1	1
Acetylcholine receptor subunit alpha	Homo sapiens (human)	IC50	11.0000	2	2
Acetylcholine receptor subunit alpha	Tetronarce californica (Pacific electric ray)	IC50	0.0025	2	2
Acetylcholine receptor subunit alpha	Homo sapiens (human)	Ki	3.3139	4	4
Acetylcholine receptor subunit alpha	Tetronarce californica (Pacific electric ray)	Ki	8.1350	2	2
Acetylcholine receptor subunit beta	Homo sapiens (human)	IC50	1.0000	1	1
Acetylcholine receptor subunit beta	Tetronarce californica (Pacific electric ray)	IC50	0.0025	2	2
Acetylcholine receptor subunit beta	Homo sapiens (human)	Ki	3.3139	4	4
Acetylcholine receptor subunit beta	Tetronarce californica (Pacific electric ray)	Ki	8.1350	2	2
Acetylcholine receptor subunit beta-like 2	Drosophila melanogaster (fruit fly)	IC50	4.0000	1	1
Acetylcholine receptor subunit beta-like 2	Drosophila melanogaster (fruit fly)	Ki	2.7000	1	1
Acetylcholine receptor subunit delta	Homo sapiens (human)	IC50	1.0000	1	1
Acetylcholine receptor subunit delta	Tetronarce californica (Pacific electric ray)	IC50	0.0025	2	2
Acetylcholine receptor subunit delta	Homo sapiens (human)	Ki	3.3139	4	4
Acetylcholine receptor subunit delta	Tetronarce californica (Pacific electric ray)	Ki	8.1350	2	2
Acetylcholine receptor subunit gamma	Homo sapiens (human)	IC50	1.0000	1	1
Acetylcholine receptor subunit gamma	Tetronarce californica (Pacific electric ray)	IC50	0.0025	2	2
Acetylcholine receptor subunit gamma	Homo sapiens (human)	Ki	3.3139	4	4
Acetylcholine receptor subunit gamma	Tetronarce californica (Pacific electric ray)	Ki	8.1350	2	2
Acetylcholine-binding protein	Lymnaea stagnalis (great pond snail)	Ki	0.2236	7	8
Acetylcholinesterase	Electrophorus electricus (electric eel)	IC50	132.1300	2	2
Acetylcholinesterase	Homo sapiens (human)	IC50	5.4350	2	2
Acetylcholinesterase	Electrophorus electricus (electric eel)	Ki	100.0000	1	1
Acetylcholinesterase	Homo sapiens (human)	Ki	65.8000	1	1
Activin receptor type-1B	Homo sapiens (human)	IC50	44.0000	1	1
Adenosine receptor A1	Bos taurus (cattle)	IC50	1,006,650,005.0433	3	3
Adenosine receptor A1	Homo sapiens (human)	IC50	17.1040	1	1
Adenosine receptor A1	Rattus norvegicus (Norway rat)	IC50	19.0000	2	2
Adenosine receptor A1	Bos taurus (cattle)	Ki	4.1143	7	7
Adenosine receptor A1	Cavia porcellus (domestic guinea pig)	Ki	21.3333	6	6
Adenosine receptor A1	Gallus gallus (chicken)	Ki	6.0000	1	1
Adenosine receptor A1	Homo sapiens (human)	Ki	6.6399	18	18
Adenosine receptor A1	Rattus norvegicus (Norway rat)	Ki	9.2781	31	37
Adenosine receptor A2a	Homo sapiens (human)	IC50	12.0070	1	1
Adenosine receptor A2a	Cavia porcellus (domestic guinea pig)	Ki	14.0000	2	2
Adenosine receptor A2a	Homo sapiens (human)	Ki	8.5486	27	27
Adenosine receptor A2a	Rattus norvegicus (Norway rat)	Ki	15.9652	24	31
Adenosine receptor A2b	Homo sapiens (human)	Ki	10.1426	19	19
Adenosine receptor A2b	Rattus norvegicus (Norway rat)	Ki	15.3896	18	24
Adenosine receptor A3	Homo sapiens (human)	Ki	54.8657	20	20
Adenosine receptor A3	Rattus norvegicus (Norway rat)	Ki	45.4056	8	9
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	Homo sapiens (human)	IC50	8.2000	1	1
Aldo-keto reductase family 1 member A1	Homo sapiens (human)	IC50	50.0000	1	1
Aldo-keto reductase family 1 member B1	Bos taurus (cattle)	IC50	5.1620	2	2
Aldo-keto reductase family 1 member B1	Homo sapiens (human)	IC50	57.5860	5	5
Aldo-keto reductase family 1 member B1	Rattus norvegicus (Norway rat)	IC50	2.6635	2	2
Aldo-keto reductase family 1 member B1	Rattus norvegicus (Norway rat)	Ki	3.7560	1	1
Aldo-keto reductase family 1 member B10	Homo sapiens (human)	IC50	20.4083	6	6
Aldo-keto reductase family 1 member B10	Homo sapiens (human)	Ki	0.0460	1	1
Aldo-keto reductase family 1 member C1	Homo sapiens (human)	IC50	21.1200	2	2
Aldo-keto reductase family 1 member C2	Homo sapiens (human)	IC50	15.8800	2	2
Aldo-keto reductase family 1 member C3	Homo sapiens (human)	IC50	2.7050	2	2
Aldo-keto reductase family 1 member C4	Homo sapiens (human)	IC50	5.2750	2	2
ALK tyrosine kinase receptor	Homo sapiens (human)	IC50	10.7849	3	3
alkaline phosphatase, germ cell type preproprotein	Homo sapiens (human)	IC50	100.0000	1	1
alkaline phosphatase, intestinal	Homo sapiens (human)	IC50	100.0000	1	1
Alkaline phosphatase, placental type	Homo sapiens (human)	IC50	400.0000	4	4
Alkaline phosphatase, tissue-nonspecific isozyme	Homo sapiens (human)	IC50	28.2683	4	6
Alkaline phosphatase, tissue-nonspecific isozyme	Homo sapiens (human)	Ki	49.0000	1	2
Alkaline phosphatase, tissue-nonspecific isozyme	Bos taurus (cattle)	IC50	19.4060	5	5
Alkaline phosphatase, tissue-nonspecific isozyme	Bos taurus (cattle)	Ki	1.8100	1	1
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	Homo sapiens (human)	IC50	100.0000	1	1
Alpha-1A adrenergic receptor	Rattus norvegicus (Norway rat)	IC50	5.4000	1	1
Alpha-1B adrenergic receptor	Rattus norvegicus (Norway rat)	IC50	5.4000	1	1
Alpha-1D adrenergic receptor	Rattus norvegicus (Norway rat)	IC50	5.4000	1	1
Alpha-amylase 1A	Homo sapiens (human)	IC50	18.4000	2	2
Alpha-synuclein	Homo sapiens (human)	IC50	63.3400	3	3
Amine oxidase [flavin-containing] A	Homo sapiens (human)	IC50	3.8500	4	4
Amine oxidase [flavin-containing] A	Homo sapiens (human)	Ki	0.7100	1	1
Amine oxidase [flavin-containing] B	Homo sapiens (human)	IC50	16.8550	4	4
Amine oxidase [flavin-containing] B	Homo sapiens (human)	Ki	21.5000	1	1
Aminopeptidase N	Homo sapiens (human)	IC50	15.5000	1	1
Aminopeptidase N	Sus scrofa (pig)	IC50	15.5000	1	1
Amyloid-beta precursor protein	Homo sapiens (human)	IC50	9.7426	31	31
Androgen receptor	Homo sapiens (human)	IC50	10.0000	1	1
Angiopoietin-1 receptor	Homo sapiens (human)	IC50	2.7608	4	4
Angiotensin-converting enzyme	Oryctolagus cuniculus (rabbit)	IC50	290.0000	2	2
AP2-associated protein kinase 1	Homo sapiens (human)	IC50	0.0462	2	2
Aromatase	Homo sapiens (human)	IC50	0.0180	1	1
ATP-binding cassette sub-family C member 3	Homo sapiens (human)	IC50	133.0000	1	5
ATP-dependent translocase ABCB1	Homo sapiens (human)	IC50	19.6000	1	1
Aurora kinase A	Homo sapiens (human)	IC50	15.9185	2	2
Aurora kinase B	Homo sapiens (human)	IC50	35.1267	3	3
BDNF/NT-3 growth factors receptor	Homo sapiens (human)	IC50	0.5250	2	2
Beta lactamase (plasmid)	Pseudomonas aeruginosa	IC50	7.7510	1	1
Beta-adrenergic receptor kinase 1	Bos taurus (cattle)	IC50	130.0000	1	1
Beta-glucuronidase	Escherichia coli K-12	IC50	12.1500	1	1
Beta-glucuronidase	Rattus norvegicus (Norway rat)	IC50	97.2100	1	1
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	Plasmodium falciparum (malaria parasite P. falciparum)	IC50	5.0000	1	1
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	Plasmodium falciparum (malaria parasite P. falciparum)	Ki	11.5000	1	1
Beta-secretase 1	Homo sapiens (human)	IC50	343.0000	1	1
Bifunctional epoxide hydrolase 2	Homo sapiens (human)	IC50	10.0000	1	1
Bile salt export pump	Homo sapiens (human)	IC50	288.7510	3	10
Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)	IC50	4.5100	3	3
Bromodomain-containing protein 4	Homo sapiens (human)	IC50	5.1900	1	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	Homo sapiens (human)	IC50	320.0000	1	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	Bos taurus (cattle)	IC50	340.4000	5	5
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	Bos taurus (cattle)	IC50	300.5000	4	4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	Homo sapiens (human)	IC50	320.0000	1	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	Homo sapiens (human)	IC50	320.0000	1	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)	IC50	40.0000	1	1
Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)	IC50	30.0000	1	1
cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)	IC50	20.0000	1	1
cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)	IC50	20.0000	1	1
cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)	IC50	20.0000	1	1
cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)	IC50	30.0000	1	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)	IC50	574.2500	4	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)	Ki	530.0000	1	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Rattus norvegicus (Norway rat)	Ki	530.0000	1	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)	IC50	527.7500	4	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)	Ki	530.0000	1	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Rattus norvegicus (Norway rat)	Ki	530.0000	1	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	Homo sapiens (human)	IC50	637.0000	3	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	Homo sapiens (human)	Ki	530.0000	1	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	Rattus norvegicus (Norway rat)	Ki	530.0000	1	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)	IC50	637.0000	3	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)	Ki	530.0000	1	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Rattus norvegicus (Norway rat)	Ki	530.0000	1	1
Canalicular multispecific organic anion transporter 1	Homo sapiens (human)	IC50	133.0000	1	5
Carbonic anhydrase 1	Homo sapiens (human)	Ki	4.5480	2	5
Carbonic anhydrase 12	Homo sapiens (human)	Ki	0.0603	1	1
Carbonic anhydrase 2	Homo sapiens (human)	Ki	7.4053	3	6
Carbonic anhydrase 3	Bos taurus (cattle)	Ki	3.1850	1	4
Carbonic anhydrase 4	Homo sapiens (human)	Ki	21.0055	3	6
Carbonic anhydrase 5A, mitochondrial	Homo sapiens (human)	Ki	31.0000	1	1
Carbonic anhydrase 7	Homo sapiens (human)	Ki	0.0047	1	1
Carbonic anhydrase 9	Homo sapiens (human)	Ki	23.0000	1	1
Casein kinase I isoform alpha	Homo sapiens (human)	IC50	15.0005	2	2
Casein kinase II subunit alpha	Homo sapiens (human)	IC50	10.5000	3	3
Casein kinase II subunit alpha 3	Homo sapiens (human)	IC50	0.5000	1	1
Casein kinase II subunit alpha'	Homo sapiens (human)	IC50	0.8333	3	3
Casein kinase II subunit beta	Homo sapiens (human)	IC50	0.8333	3	3
Cationic trypsin	Bos taurus (cattle)	IC50	35.3000	1	1
CDGSH iron-sulfur domain-containing protein 1	Homo sapiens (human)	IC50	2.3600	1	1
CDGSH iron-sulfur domain-containing protein 1	Homo sapiens (human)	Ki	0.1010	1	1
Cereblon isoform 4	Magnetospirillum gryphiswaldense	Ki	1.9500	1	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	Homo sapiens (human)	IC50	210.0000	1	1
cGMP-dependent protein kinase 1	Homo sapiens (human)	IC50	30.0000	2	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	Homo sapiens (human)	IC50	300.0000	2	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	Homo sapiens (human)	IC50	300.0000	2	2
Chain A, Casein Kinase Ii Subunit Alpha	Zea mays	IC50	0.3500	1	3
Chain A, Pyridoxal Kinase	Homo sapiens (human)	Ki	50.0000	1	2
Chemotaxis protein CheA	Escherichia coli K-12	IC50	111.0000	1	1
Chitotriosidase-1	Homo sapiens (human)	IC50	1,000.0000	1	2
Cholinesterase	Equus caballus (horse)	IC50	300.0000	1	1
Cholinesterase	Homo sapiens (human)	IC50	5.0000	1	1
Cholinesterase	Equus caballus (horse)	Ki	100.0000	1	1
Collagenase 3	Homo sapiens (human)	IC50	10.0500	1	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	Homo sapiens (human)	IC50	0.1853	9	9
Corticosteroid 11-beta-dehydrogenase isozyme 1	Mus musculus (house mouse)	IC50	0.0124	6	6
Corticosteroid 11-beta-dehydrogenase isozyme 1	Rattus norvegicus (Norway rat)	IC50	0.0900	1	1
Corticosteroid 11-beta-dehydrogenase isozyme 2	Homo sapiens (human)	IC50	0.1035	5	5
Corticosteroid 11-beta-dehydrogenase isozyme 2	Rattus norvegicus (Norway rat)	IC50	0.3600	2	2
CREB-binding protein	Homo sapiens (human)	IC50	25.0000	4	4
Cruzipain	Trypanosoma cruzi	IC50	91.5000	2	2
Cyclin homolog	Herpesvirus saimiri (strain 11)	IC50	77.7000	1	4
Cyclin-A1	Homo sapiens (human)	IC50	30.0000	1	1
Cyclin-A2	Homo sapiens (human)	IC50	30.0000	1	1
Cyclin-dependent kinase 1	Homo sapiens (human)	IC50	345.4000	3	3
Cyclin-dependent kinase 1	Oryzias latipes (Japanese medaka)	IC50	77.7000	1	4
Cyclin-dependent kinase 2	Homo sapiens (human)	IC50	52.5000	4	4
Cyclin-dependent kinase 5 activator 1	Homo sapiens (human)	IC50	53.5143	4	7
Cyclin-dependent kinase 6	Homo sapiens (human)	IC50	122.1600	2	5
Cyclin-dependent kinase 8	Homo sapiens (human)	IC50	1.0000	1	1
Cyclin-dependent kinase 9	Homo sapiens (human)	IC50	30.0000	1	1
Cyclin-dependent-like kinase 5	Homo sapiens (human)	IC50	46.9500	5	8
Cyclin-T1	Homo sapiens (human)	IC50	30.0000	1	1
Cysteine protease	Trypanosoma brucei rhodesiense	IC50	7.7500	1	1
Cytochrome P450 1A1	Homo sapiens (human)	IC50	1.2490	1	1
Cytochrome P450 1A1	Homo sapiens (human)	Ki	1.8967	2	3
Cytochrome P450 1A2	Homo sapiens (human)	IC50	1,401.1233	3	3
Cytochrome P450 1B1	Homo sapiens (human)	IC50	0.2195	2	2
Cytochrome P450 1B1	Homo sapiens (human)	Ki	1.2280	2	2
Cytochrome P450 2A13	Homo sapiens (human)	Ki	72.0000	1	1
Cytochrome P450 2A5	Mus musculus (house mouse)	IC50	159.9560	1	1
Cytochrome P450 2A6	Homo sapiens (human)	IC50	210.6763	2	3
Cytochrome P450 2A6	Homo sapiens (human)	Ki	46.2667	3	3
Cytochrome P450 2C19	Homo sapiens (human)	IC50	100.0000	1	1
Cytochrome P450 2C19	Homo sapiens (human)	Ki	0.0001	1	1
Cytochrome P450 2C9	Homo sapiens (human)	IC50	50.0046	2	2
Cytochrome P450 2D6	Homo sapiens (human)	IC50	100.0000	1	1
Cytochrome P450 2D6	Homo sapiens (human)	Ki	0.0001	1	1
Cytochrome P450 3A4	Homo sapiens (human)	IC50	42.1031	3	3
Cytochrome P450 3A4	Homo sapiens (human)	Ki	0.0001	1	1
Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)	IC50	30.0000	1	1
Cytosol aminopeptidase	Sus scrofa (pig)	IC50	49.6000	1	1
D-amino-acid oxidase	Sus scrofa (pig)	IC50	1.0700	2	2
D(3) dopamine receptor	Rattus norvegicus (Norway rat)	Ki	0.0006	1	1
Death-associated protein kinase 1	Homo sapiens (human)	IC50	25.5000	2	2
Death-associated protein kinase 3	Homo sapiens (human)	IC50	30.0000	1	1
Delta-type opioid receptor	Homo sapiens (human)	Ki	26.0000	1	1
Delta-type opioid receptor	Mus musculus (house mouse)	Ki	0.4400	1	1
Delta-type opioid receptor	Rattus norvegicus (Norway rat)	Ki	0.1100	1	1
Dipeptidyl peptidase 3	Homo sapiens (human)	IC50	22.0000	1	1
Dipeptidyl peptidase 4	Homo sapiens (human)	IC50	0.1200	1	1
Discoidin domain-containing receptor 2	Homo sapiens (human)	IC50	0.2708	4	4
DNA damage-binding protein 1	Homo sapiens (human)	IC50	1.7972	3	5
DNA topoisomerase 1	Rattus norvegicus (Norway rat)	IC50	2.8300	2	2
DNA-dependent protein kinase catalytic subunit	Homo sapiens (human)	IC50	50.0000	1	1
Endochitinase B1	Aspergillus fumigatus	IC50	1,000.0000	1	2
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	Escherichia coli K-12	Ki	7.0500	1	1
Enoyl-acyl-carrier protein reductase	Plasmodium falciparum (malaria parasite P. falciparum)	IC50	2.0000	2	2
Enoyl-acyl-carrier protein reductase	Plasmodium falciparum (malaria parasite P. falciparum)	Ki	2.1000	1	1
Ephrin type-A receptor 1	Homo sapiens (human)	IC50	0.6300	1	1
Ephrin type-A receptor 2	Homo sapiens (human)	IC50	0.1600	1	1
Ephrin type-A receptor 3	Homo sapiens (human)	IC50	1.1000	2	2
Ephrin type-A receptor 4	Homo sapiens (human)	IC50	0.0700	1	1
Ephrin type-A receptor 5	Homo sapiens (human)	IC50	0.0900	1	1
Ephrin type-A receptor 7	Homo sapiens (human)	IC50	1.0000	1	1
Ephrin type-A receptor 8	Homo sapiens (human)	IC50	1.0000	1	1
Ephrin type-B receptor 1	Homo sapiens (human)	IC50	0.1100	1	1
Ephrin type-B receptor 2	Homo sapiens (human)	IC50	0.5800	2	2
Ephrin type-B receptor 3	Homo sapiens (human)	IC50	9.4000	1	1
Ephrin type-B receptor 4	Homo sapiens (human)	IC50	25.4500	2	2
Epidermal growth factor receptor	Homo sapiens (human)	IC50	55.9623	18	20
Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)	IC50	1.0000	1	1
Estrogen receptor	Homo sapiens (human)	IC50	7.9120	1	1
Estrogen receptor	Homo sapiens (human)	Ki	2.2600	1	1
Fatty acid synthase	Gallus gallus (chicken)	IC50	62.5000	1	1
Fatty acid synthase	Homo sapiens (human)	IC50	62.5000	1	1
Fibroblast growth factor receptor 1	Homo sapiens (human)	IC50	6.0163	5	7
Fibroblast growth factor receptor 2	Homo sapiens (human)	IC50	24.0000	1	1
Fibroblast growth factor receptor 3	Homo sapiens (human)	IC50	30.0000	1	1
Fibroblast growth factor receptor 4	Homo sapiens (human)	IC50	7.0000	1	1
Focal adhesion kinase 1	Homo sapiens (human)	IC50	1.8000	2	2
G protein-coupled receptor kinase 5	Homo sapiens (human)	IC50	15.4150	2	2
G protein-coupled receptor kinase 6	Homo sapiens (human)	IC50	30.0000	1	1
G-protein coupled receptor 35	Homo sapiens (human)	IC50	18.6000	1	1
G1/S-specific cyclin-E1	Homo sapiens (human)	IC50	30.0000	1	1
G2/mitotic-specific cyclin-B	Marthasterias glacialis (spiny starfish)	IC50	77.7000	1	4
G2/mitotic-specific cyclin-B1	Homo sapiens (human)	IC50	18.1000	2	2
G2/mitotic-specific cyclin-B2	Homo sapiens (human)	IC50	6.2000	1	1
G2/mitotic-specific cyclin-B3	Homo sapiens (human)	IC50	6.2000	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	Homo sapiens (human)	Ki	113.0000	1	2
Gamma-aminobutyric acid receptor subunit alpha-2	Homo sapiens (human)	Ki	113.0000	1	2
Gamma-aminobutyric acid receptor subunit alpha-3	Homo sapiens (human)	Ki	113.0000	1	2
Gamma-aminobutyric acid receptor subunit alpha-4	Homo sapiens (human)	Ki	113.0000	1	2
Gamma-aminobutyric acid receptor subunit alpha-5	Homo sapiens (human)	Ki	113.0000	1	2
Gamma-aminobutyric acid receptor subunit alpha-6	Homo sapiens (human)	Ki	113.0000	1	2
Gamma-aminobutyric acid receptor subunit beta-1	Homo sapiens (human)	Ki	113.0000	1	2
Gamma-aminobutyric acid receptor subunit beta-2	Homo sapiens (human)	Ki	113.0000	1	2
Gamma-aminobutyric acid receptor subunit beta-3	Homo sapiens (human)	Ki	113.0000	1	2
Gamma-aminobutyric acid receptor subunit delta	Homo sapiens (human)	Ki	113.0000	1	2
Gamma-aminobutyric acid receptor subunit epsilon	Homo sapiens (human)	Ki	113.0000	1	2
Gamma-aminobutyric acid receptor subunit gamma-1	Homo sapiens (human)	Ki	113.0000	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	Homo sapiens (human)	Ki	113.0000	1	2
Gamma-aminobutyric acid receptor subunit gamma-3	Homo sapiens (human)	Ki	113.0000	1	2
Gamma-aminobutyric acid receptor subunit pi	Homo sapiens (human)	Ki	113.0000	1	2
Gamma-aminobutyric acid receptor subunit theta	Homo sapiens (human)	Ki	113.0000	1	2
Genome polyprotein	Zika virus	IC50	53.0000	1	1
Glutathione S-transferase P	Homo sapiens (human)	IC50	34.7500	2	2
Glycogen phosphorylase, muscle form	Oryctolagus cuniculus (rabbit)	IC50	66.0000	1	1
Glycogen synthase kinase-3 alpha	Homo sapiens (human)	IC50	0.8000	1	1
Glycogen synthase kinase-3 beta	Homo sapiens (human)	IC50	20.6350	5	6
Glycogen synthase kinase-3 beta	Rattus norvegicus (Norway rat)	IC50	62.1732	2	5
Heat shock protein beta-1	Homo sapiens (human)	IC50	0.0580	1	1
Heme oxygenase 1	Rattus norvegicus (Norway rat)	IC50	10.0000	1	1
Heme oxygenase 2	Rattus norvegicus (Norway rat)	IC50	10.0000	1	1
Hepatocyte growth factor receptor	Homo sapiens (human)	IC50	10.2858	7	7
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	Homo sapiens (human)	IC50	200.0000	1	1
High affinity nerve growth factor receptor	Homo sapiens (human)	IC50	0.5800	2	2
histidine kinase	Streptococcus pneumoniae TIGR4	IC50	216.0000	1	1
Histone acetyltransferase p300	Homo sapiens (human)	IC50	21.9167	6	6
Histone deacetylase 1	Homo sapiens (human)	IC50	187.0000	1	1
Histone deacetylase 1	Homo sapiens (human)	Ki	50.7900	1	1
Histone deacetylase 11	Homo sapiens (human)	IC50	187.0000	1	1
Histone deacetylase 2	Homo sapiens (human)	IC50	187.0000	1	1
Histone deacetylase 2	Homo sapiens (human)	Ki	97.6700	1	1
Histone deacetylase 3	Homo sapiens (human)	IC50	187.0000	1	1
Histone deacetylase 4	Homo sapiens (human)	IC50	187.0000	1	1
Histone deacetylase 5	Homo sapiens (human)	IC50	187.0000	1	1
Histone deacetylase 6	Homo sapiens (human)	IC50	187.0000	1	1
Histone deacetylase 7	Homo sapiens (human)	IC50	187.0000	1	1
Histone deacetylase 8	Homo sapiens (human)	IC50	187.0000	1	1
Histone deacetylase 8	Homo sapiens (human)	Ki	64.9800	1	1
Histone deacetylase 9	Homo sapiens (human)	IC50	187.0000	1	1
Histone-lysine N-methyltransferase SETD7	Homo sapiens (human)	IC50	6.0800	1	1
Homeobox protein Nkx-2.5	Mus musculus (house mouse)	IC50	22.0000	1	1
Homeodomain-interacting protein kinase 1	Homo sapiens (human)	IC50	30.0000	1	1
Homeodomain-interacting protein kinase 3	Homo sapiens (human)	IC50	30.0000	1	1
Hydroxycarboxylic acid receptor 2	Homo sapiens (human)	Ki	0.1800	1	1
hypothetical protein SA1422	Staphylococcus aureus subsp. aureus N315	IC50	42.9000	2	2
Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)	IC50	25.0000	2	2
Inositol hexakisphosphate kinase 2	Homo sapiens (human)	IC50	1.3000	1	1
Inositol polyphosphate multikinase	Homo sapiens (human)	IC50	5.5000	1	1
Insulin receptor	Homo sapiens (human)	IC50	16.6000	2	2
Insulin receptor-related protein	Homo sapiens (human)	IC50	30.0000	1	1
Insulin-like growth factor 1 receptor	Homo sapiens (human)	IC50	30.0000	1	1
Integrase	Human immunodeficiency virus 1	IC50	25.3329	10	10
integrase, partial	Human immunodeficiency virus 1	IC50	7.8945	2	2
Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)	IC50	30.0000	1	1
Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)	IC50	30.0000	1	1
Interstitial collagenase	Homo sapiens (human)	IC50	3.0300	1	1
intestinal alkaline phosphatase precursor	Mus musculus (house mouse)	IC50	18.7000	1	1
Intestinal-type alkaline phosphatase	Bos taurus (cattle)	IC50	171.7220	5	5
Intestinal-type alkaline phosphatase	Homo sapiens (human)	IC50	171.7017	5	6
Kappa-type opioid receptor	Cavia porcellus (domestic guinea pig)	IC50	0.6600	1	1
Lactoylglutathione lyase	Homo sapiens (human)	IC50	7.7000	1	1
Lactoylglutathione lyase	Homo sapiens (human)	Ki	0.0050	1	1
Lactoylglutathione lyase	Mus musculus (house mouse)	Ki	0.2900	1	1
large T antigen	Betapolyomavirus macacae	IC50	11.9000	1	1
lens epithelium-derived growth factor p75	Homo sapiens (human)	IC50	7.8945	2	2
Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)	IC50	0.0215	2	2
Liver carboxylesterase B-1	Rattus norvegicus (Norway rat)	IC50	0.0450	1	1
Lysine-specific histone demethylase 1A	Homo sapiens (human)	IC50	9.6000	1	1
M-phase inducer phosphatase 1	Homo sapiens (human)	IC50	25.0000	1	1
M1-family alanyl aminopeptidase	Plasmodium falciparum 3D7	IC50	22.8600	1	1
Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)	IC50	6.0710	5	5
Macrophage metalloelastase	Homo sapiens (human)	IC50	0.9800	1	1
Macrophage-stimulating protein receptor	Homo sapiens (human)	IC50	30.0000	1	1
MAP kinase-activated protein kinase 2	Homo sapiens (human)	IC50	30.0000	1	1
MAP kinase-activated protein kinase 3	Homo sapiens (human)	IC50	30.0000	1	1
MAP kinase-activated protein kinase 5	Homo sapiens (human)	IC50	30.0000	1	1
MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)	IC50	0.1790	1	1
MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)	IC50	0.5790	1	1
Mast/stem cell growth factor receptor Kit	Homo sapiens (human)	GI50	0.1986	53	53
Mast/stem cell growth factor receptor Kit	Mus musculus (house mouse)	GI50	0.0030	1	1
Mast/stem cell growth factor receptor Kit	Homo sapiens (human)	IC50	1.7875	20	20
Mast/stem cell growth factor receptor Kit	Homo sapiens (human)	Ki	0.0040	1	1
Matrix metalloproteinase-9	Homo sapiens (human)	IC50	5.6200	1	1
Microtubule-associated protein tau	Homo sapiens (human)	IC50	54.8750	4	4
Misshapen-like kinase 1	Homo sapiens (human)	IC50	0.0400	1	1
Mitogen-activated protein kinase 1	Homo sapiens (human)	IC50	4.9430	2	2
Mitogen-activated protein kinase 10	Homo sapiens (human)	IC50	6.5400	4	5
Mitogen-activated protein kinase 11	Homo sapiens (human)	IC50	2.2048	5	5
Mitogen-activated protein kinase 12	Homo sapiens (human)	IC50	0.2298	5	5
Mitogen-activated protein kinase 13	Homo sapiens (human)	IC50	0.1057	3	3
Mitogen-activated protein kinase 14	Homo sapiens (human)	IC50	1.0756	19	20
Mitogen-activated protein kinase 14	Homo sapiens (human)	Ki	0.0186	4	4
Mitogen-activated protein kinase 3	Homo sapiens (human)	IC50	25.0000	2	2
Mitogen-activated protein kinase 8	Homo sapiens (human)	IC50	13.6667	3	3
Mitogen-activated protein kinase 9	Homo sapiens (human)	IC50	0.2989	8	8
Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)	IC50	1.0000	1	1
Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)	IC50	30.0000	1	1
Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)	IC50	0.9000	1	1
Mitogen-activated protein kinase kinase kinase 9	Homo sapiens (human)	IC50	30.0000	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)	IC50	1.0000	1	1
Mu-type opioid receptor	Cavia porcellus (domestic guinea pig)	IC50	0.0180	1	1
Mu-type opioid receptor	Cavia porcellus (domestic guinea pig)	Ki	0.2260	2	2
Mu-type opioid receptor	Rattus norvegicus (Norway rat)	Ki	0.4400	1	1
Multidrug resistance-associated protein 4	Homo sapiens (human)	IC50	133.0000	1	5
Muscarinic acetylcholine receptor M1	Rattus norvegicus (Norway rat)	IC50	360.0000	1	2
Muscarinic acetylcholine receptor M2	Rattus norvegicus (Norway rat)	IC50	360.0000	1	1
Muscarinic acetylcholine receptor M3	Rattus norvegicus (Norway rat)	IC50	360.0000	1	1
Muscarinic acetylcholine receptor M4	Rattus norvegicus (Norway rat)	IC50	360.0000	1	1
Muscarinic acetylcholine receptor M4	Mus musculus (house mouse)	Ki	2.1100	1	1
Muscarinic acetylcholine receptor M4	Rattus norvegicus (Norway rat)	Ki	1.0597	2	2
Muscarinic acetylcholine receptor M5	Rattus norvegicus (Norway rat)	IC50	360.0000	1	1
NACHT, LRR and PYD domains-containing protein 3	Homo sapiens (human)	IC50	24.2000	1	1
NAD-dependent protein deacetylase sirtuin-2	Homo sapiens (human)	IC50	122.7000	1	1
NADPH oxidase 4	Homo sapiens (human)	IC50	0.8500	1	1
Neuraminidase	Influenza A virus (A/Wilson-Smith/1933(H1N1))	IC50	32.6500	4	4
Neuraminidase	Influenza A virus (A/Wilson-Smith/1933(H1N1))	Ki	19.6000	1	1
Neuronal acetylcholine receptor subunit alpha-10	Rattus norvegicus (Norway rat)	IC50	0.0050	2	2
Neuronal acetylcholine receptor subunit alpha-10	Rattus norvegicus (Norway rat)	Ki	0.0070	3	4
Neuronal acetylcholine receptor subunit alpha-2	Mus musculus (house mouse)	IC50	0.0040	1	1
Neuronal acetylcholine receptor subunit alpha-2	Rattus norvegicus (Norway rat)	IC50	0.0050	2	2
Neuronal acetylcholine receptor subunit alpha-2	Homo sapiens (human)	Ki	0.0595	3	3
Neuronal acetylcholine receptor subunit alpha-2	Mus musculus (house mouse)	Ki	0.0012	1	1
Neuronal acetylcholine receptor subunit alpha-2	Rattus norvegicus (Norway rat)	Ki	0.0438	27	28
Neuronal acetylcholine receptor subunit alpha-3	Homo sapiens (human)	IC50	0.3899	4	4
Neuronal acetylcholine receptor subunit alpha-3	Mus musculus (house mouse)	IC50	0.0040	1	1
Neuronal acetylcholine receptor subunit alpha-3	Rattus norvegicus (Norway rat)	IC50	5.0025	4	4
Neuronal acetylcholine receptor subunit alpha-3	Homo sapiens (human)	Ki	0.3763	20	20
Neuronal acetylcholine receptor subunit alpha-3	Mus musculus (house mouse)	Ki	0.0841	2	2
Neuronal acetylcholine receptor subunit alpha-3	Rattus norvegicus (Norway rat)	Ki	0.2178	37	42
Neuronal acetylcholine receptor subunit alpha-4	Homo sapiens (human)	IC50	0.3456	10	12
Neuronal acetylcholine receptor subunit alpha-4	Mus musculus (house mouse)	IC50	0.0055	2	2
Neuronal acetylcholine receptor subunit alpha-4	Rattus norvegicus (Norway rat)	IC50	0.0046	3	3
Neuronal acetylcholine receptor subunit alpha-4	Gallus gallus (chicken)	Ki	0.0019	1	1
Neuronal acetylcholine receptor subunit alpha-4	Homo sapiens (human)	Ki	0.3444	30	30
Neuronal acetylcholine receptor subunit alpha-4	Mus musculus (house mouse)	Ki	0.0012	1	1
Neuronal acetylcholine receptor subunit alpha-4	Rattus norvegicus (Norway rat)	Ki	0.0204	72	85
Neuronal acetylcholine receptor subunit alpha-5	Mus musculus (house mouse)	IC50	0.0040	1	1
Neuronal acetylcholine receptor subunit alpha-5	Rattus norvegicus (Norway rat)	IC50	0.0050	2	2
Neuronal acetylcholine receptor subunit alpha-5	Mus musculus (house mouse)	Ki	0.0012	1	1
Neuronal acetylcholine receptor subunit alpha-5	Rattus norvegicus (Norway rat)	Ki	0.0070	3	4
Neuronal acetylcholine receptor subunit alpha-6	Homo sapiens (human)	IC50	0.0848	1	1
Neuronal acetylcholine receptor subunit alpha-6	Mus musculus (house mouse)	IC50	0.0040	1	1
Neuronal acetylcholine receptor subunit alpha-6	Rattus norvegicus (Norway rat)	IC50	0.0050	2	2
Neuronal acetylcholine receptor subunit alpha-6	Mus musculus (house mouse)	Ki	0.0012	1	1
Neuronal acetylcholine receptor subunit alpha-6	Rattus norvegicus (Norway rat)	Ki	0.0070	3	4
Neuronal acetylcholine receptor subunit alpha-7	Homo sapiens (human)	IC50	14.3000	2	2
Neuronal acetylcholine receptor subunit alpha-7	Mus musculus (house mouse)	IC50	0.0040	1	1
Neuronal acetylcholine receptor subunit alpha-7	Rattus norvegicus (Norway rat)	IC50	0.0087	3	3
Neuronal acetylcholine receptor subunit alpha-7	Homo sapiens (human)	Ki	5.9317	17	19
Neuronal acetylcholine receptor subunit alpha-7	Mus musculus (house mouse)	Ki	0.2406	2	2
Neuronal acetylcholine receptor subunit alpha-7	Rattus norvegicus (Norway rat)	Ki	3.1729	16	20
Neuronal acetylcholine receptor subunit alpha-9	Rattus norvegicus (Norway rat)	IC50	0.0041	3	3
Neuronal acetylcholine receptor subunit alpha-9	Rattus norvegicus (Norway rat)	Ki	0.0070	3	4
Neuronal acetylcholine receptor subunit beta-2	Homo sapiens (human)	IC50	0.3256	11	13
Neuronal acetylcholine receptor subunit beta-2	Mus musculus (house mouse)	IC50	0.0040	1	1
Neuronal acetylcholine receptor subunit beta-2	Rattus norvegicus (Norway rat)	IC50	0.0046	3	3
Neuronal acetylcholine receptor subunit beta-2	Homo sapiens (human)	Ki	0.3399	30	30
Neuronal acetylcholine receptor subunit beta-2	Mus musculus (house mouse)	Ki	0.0024	2	2
Neuronal acetylcholine receptor subunit beta-2	Rattus norvegicus (Norway rat)	Ki	0.0124	76	85
Neuronal acetylcholine receptor subunit beta-3	Homo sapiens (human)	IC50	0.0848	1	1
Neuronal acetylcholine receptor subunit beta-3	Mus musculus (house mouse)	IC50	0.0040	1	1
Neuronal acetylcholine receptor subunit beta-3	Rattus norvegicus (Norway rat)	IC50	0.0050	2	2
Neuronal acetylcholine receptor subunit beta-3	Mus musculus (house mouse)	Ki	0.0012	1	1
Neuronal acetylcholine receptor subunit beta-3	Rattus norvegicus (Norway rat)	Ki	0.0070	3	4
Neuronal acetylcholine receptor subunit beta-4	Homo sapiens (human)	IC50	0.7150	2	2
Neuronal acetylcholine receptor subunit beta-4	Mus musculus (house mouse)	IC50	0.0040	1	1
Neuronal acetylcholine receptor subunit beta-4	Rattus norvegicus (Norway rat)	IC50	5.0025	4	4
Neuronal acetylcholine receptor subunit beta-4	Homo sapiens (human)	Ki	0.3463	22	22
Neuronal acetylcholine receptor subunit beta-4	Mus musculus (house mouse)	Ki	0.0572	3	3
Neuronal acetylcholine receptor subunit beta-4	Rattus norvegicus (Norway rat)	Ki	0.1748	54	63
Neuronal proto-oncogene tyrosine-protein kinase Src	Mus musculus (house mouse)	IC50	2.2000	1	1
Neutrophil elastase	Homo sapiens (human)	IC50	12.7000	1	1
Neutrophil elastase	Homo sapiens (human)	Ki	10.1000	1	1
NT-3 growth factor receptor	Homo sapiens (human)	IC50	1.0000	1	1
NUAK family SNF1-like kinase 1	Homo sapiens (human)	IC50	15.0240	2	2
Oxoeicosanoid receptor 1	Homo sapiens (human)	IC50	0.0030	1	1
Pancreatic alpha-amylase	Sus scrofa (pig)	IC50	200.0000	1	1
PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)	IC50	30.0000	1	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Homo sapiens (human)	IC50	10.0000	1	1
perilipin-1	Homo sapiens (human)	IC50	9.1670	1	1
perilipin-5	Homo sapiens (human)	IC50	10.2320	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)	IC50	11.0000	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)	IC50	50.0000	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)	IC50	12.0000	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)	IC50	1,458.5000	2	2
Phosphodiesterase	Bos taurus (cattle)	IC50	250.3333	6	6
Phosphodiesterase	Bos taurus (cattle)	Ki	77.0000	1	1
Phospholipase A-2-activating protein	Homo sapiens (human)	IC50	5.0000	1	2
Phospholipase A2	Homo sapiens (human)	IC50	11.1000	1	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)	IC50	30.0000	1	1
Platelet-activating factor receptor	Cavia porcellus (domestic guinea pig)	IC50	200.0000	1	1
Platelet-derived growth factor receptor alpha	Homo sapiens (human)	GI50	0.3305	2	2
Platelet-derived growth factor receptor alpha	Homo sapiens (human)	IC50	6.0488	5	5
Platelet-derived growth factor receptor alpha	Mus musculus (house mouse)	IC50	0.0186	7	7
Platelet-derived growth factor receptor beta	Homo sapiens (human)	GI50	0.1140	1	1
Platelet-derived growth factor receptor beta	Homo sapiens (human)	IC50	12.6275	23	25
Platelet-derived growth factor receptor beta	Mus musculus (house mouse)	IC50	0.0186	7	7
Platelet-derived growth factor receptor beta	Homo sapiens (human)	Ki	0.0080	1	1
Poly [ADP-ribose] polymerase 1	Homo sapiens (human)	IC50	4.2329	1	2
Poly [ADP-ribose] polymerase tankyrase-1	Homo sapiens (human)	IC50	2.3994	1	2
Poly [ADP-ribose] polymerase tankyrase-2	Homo sapiens (human)	IC50	1.0858	1	2
Polyamine deacetylase HDAC10	Homo sapiens (human)	IC50	187.0000	1	1
Polyphenol oxidase 2	Agaricus bisporus	IC50	400.0000	1	1
Polyunsaturated fatty acid 5-lipoxygenase	Homo sapiens (human)	IC50	14.3425	4	4
Polyunsaturated fatty acid 5-lipoxygenase	Rattus norvegicus (Norway rat)	IC50	5.0000	4	4
Polyunsaturated fatty acid lipoxygenase ALOX12	Homo sapiens (human)	IC50	15.0000	1	1
Polyunsaturated fatty acid lipoxygenase ALOX15	Homo sapiens (human)	IC50	10.0433	3	3
Polyunsaturated fatty acid lipoxygenase ALOX15	Oryctolagus cuniculus (rabbit)	IC50	25.0000	1	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)	IC50	70.0000	2	2
Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)	IC50	50.1187	1	1
Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)	IC50	63.0957	1	1
Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)	IC50	132.4732	11	12
Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)	IC50	63.0957	1	1
Programmed cell death 1 ligand 1	Homo sapiens (human)	IC50	0.0100	1	1
Programmed cell death protein 1	Homo sapiens (human)	IC50	0.0100	1	1
Prostaglandin E synthase	Homo sapiens (human)	IC50	1.8000	3	3
Prostaglandin G/H synthase 1	Homo sapiens (human)	IC50	29.4165	2	2
Prostaglandin G/H synthase 1	Ovis aries (sheep)	IC50	33.4300	3	4
Prostaglandin G/H synthase 1	Rattus norvegicus (Norway rat)	IC50	3.5250	2	2
Prostaglandin G/H synthase 2	Homo sapiens (human)	IC50	42.6200	5	6
Prostaglandin G/H synthase 2	Rattus norvegicus (Norway rat)	IC50	3.5250	2	2
Proteasome subunit beta type-5	Homo sapiens (human)	IC50	5.7000	4	4
Protein cereblon	Homo sapiens (human)	IC50	7.2078	6	11
Protein cereblon	Homo sapiens (human)	Ki	9.2633	2	3
Protein delta homolog 1	Homo sapiens (human)	Ki	0.0063	1	1
Protein kinase C alpha type	Homo sapiens (human)	IC50	30.0000	1	1
Protein kinase C beta type	Homo sapiens (human)	IC50	23.4500	2	2
Protein kinase C delta type	Homo sapiens (human)	IC50	1.9000	1	1
Protein kinase C eta type	Homo sapiens (human)	IC50	30.0000	1	1
Protein kinase C gamma type	Homo sapiens (human)	IC50	30.0000	1	1
Protein kinase C theta type	Homo sapiens (human)	IC50	30.0000	1	1
Protein-tyrosine kinase 2-beta	Homo sapiens (human)	IC50	4.3000	3	3
Protein-tyrosine kinase 6	Homo sapiens (human)	IC50	30.0000	1	1
Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)	IC50	0.3971	7	7
Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)	IC50	30.0000	1	1
Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)	IC50	0.5550	1	1
Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)	IC50	11.8509	3	3
RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)	IC50	16.5333	3	3
RAC-beta serine/threonine-protein kinase	Homo sapiens (human)	IC50	30.0000	1	1
RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)	IC50	30.0000	1	1
RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)	IC50	3.4500	4	4
Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)	IC50	10.6645	2	2
Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)	IC50	30.0000	1	1
Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)	IC50	10.0000	1	1
Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)	IC50	1.1601	29	29
Renin	Homo sapiens (human)	Ki	2.3250	1	2
Replicase polyprotein 1ab	Severe acute respiratory syndrome coronavirus 2	IC50	45.8750	1	4
Replicase polyprotein 1ab	Severe acute respiratory syndrome-related coronavirus	IC50	40.7000	2	5
Rho-associated protein kinase 1	Homo sapiens (human)	IC50	30.0000	1	1
Rho-associated protein kinase 2	Homo sapiens (human)	IC50	30.0000	1	1
Ribonucleoside-diphosphate reductase large subunit	Homo sapiens (human)	IC50	997.0000	1	1
Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)	IC50	15.0656	2	2
Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)	IC50	0.1839	1	1
Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)	IC50	30.0000	1	1
Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)	IC50	30.0000	1	1
Ribosomal protein S6 kinase beta-1	Homo sapiens (human)	IC50	30.0000	1	1
RocR	Pseudomonas aeruginosa PAO1	IC50	0.0200	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	Oryctolagus cuniculus (rabbit)	IC50	3.0000	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	Oryctolagus cuniculus (rabbit)	Ki	5.8000	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	Homo sapiens (human)	IC50	7.0000	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	Homo sapiens (human)	Ki	53.0000	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	Rattus norvegicus (Norway rat)	Ki	5.8000	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	Homo sapiens (human)	IC50	7.0000	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	Homo sapiens (human)	Ki	8.6000	1	1
Seed linoleate 13S-lipoxygenase-1	Glycine max (soybean)	IC50	3.2000	3	3
Seed linoleate 13S-lipoxygenase-1	Glycine max (soybean)	Ki	121.7000	1	1
Serine/threonine-protein kinase 10	Homo sapiens (human)	IC50	1.0000	1	1
Serine/threonine-protein kinase 17A	Homo sapiens (human)	IC50	30.0000	1	1
Serine/threonine-protein kinase 3	Homo sapiens (human)	IC50	30.0000	1	1
Serine/threonine-protein kinase 33	Homo sapiens (human)	IC50	30.0000	1	1
Serine/threonine-protein kinase 4	Homo sapiens (human)	IC50	30.0000	1	1
Serine/threonine-protein kinase B-raf	Homo sapiens (human)	IC50	0.0834	1	1
Serine/threonine-protein kinase BRSK1	Homo sapiens (human)	IC50	30.0000	1	1
Serine/threonine-protein kinase Chk1	Homo sapiens (human)	IC50	15.0386	2	2
Serine/threonine-protein kinase Chk2	Homo sapiens (human)	IC50	9.5084	2	2
Serine/threonine-protein kinase D1	Homo sapiens (human)	IC50	30.0000	1	1
Serine/threonine-protein kinase D2	Homo sapiens (human)	IC50	30.0000	1	1
Serine/threonine-protein kinase MARK1	Homo sapiens (human)	IC50	30.0000	1	1
Serine/threonine-protein kinase MARK2	Homo sapiens (human)	IC50	43.0000	1	1
Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)	IC50	1.0000	1	1
Serine/threonine-protein kinase mTOR	Homo sapiens (human)	IC50	50.0000	1	1
Serine/threonine-protein kinase Nek2	Homo sapiens (human)	IC50	12.0000	1	1
Serine/threonine-protein kinase Nek3	Homo sapiens (human)	IC50	30.0000	1	1
Serine/threonine-protein kinase NLK	Homo sapiens (human)	IC50	30.0000	1	1
Serine/threonine-protein kinase PAK 1	Homo sapiens (human)	IC50	16.0000	1	1
Serine/threonine-protein kinase PAK 2	Homo sapiens (human)	IC50	30.0000	1	1
Serine/threonine-protein kinase PAK 3	Homo sapiens (human)	IC50	30.0000	1	1
Serine/threonine-protein kinase PAK 4	Homo sapiens (human)	IC50	10.3795	3	3
Serine/threonine-protein kinase PAK 4	Homo sapiens (human)	Ki	0.5000	1	1
Serine/threonine-protein kinase PAK 5	Homo sapiens (human)	IC50	30.0000	1	1
Serine/threonine-protein kinase PAK 5	Homo sapiens (human)	Ki	0.5000	1	1
Serine/threonine-protein kinase PAK 6	Homo sapiens (human)	IC50	30.0000	1	1
Serine/threonine-protein kinase PAK 6	Homo sapiens (human)	Ki	0.5000	1	1
Serine/threonine-protein kinase pim-1	Homo sapiens (human)	IC50	15.8000	2	2
Serine/threonine-protein kinase pim-2	Homo sapiens (human)	IC50	30.0000	1	1
Serine/threonine-protein kinase PLK1	Homo sapiens (human)	IC50	20.0000	2	2
Serine/threonine-protein kinase PLK1	Homo sapiens (human)	Ki	12.4000	1	4
Serine/threonine-protein kinase PLK2	Homo sapiens (human)	IC50	30.0000	1	1
Serine/threonine-protein kinase PLK2	Homo sapiens (human)	Ki	12.4000	1	4
Serine/threonine-protein kinase PLK3	Homo sapiens (human)	IC50	30.0000	1	1
Serine/threonine-protein kinase PLK3	Homo sapiens (human)	Ki	12.4000	1	4
Serine/threonine-protein kinase PLK4	Homo sapiens (human)	Ki	12.4000	1	4
Serine/threonine-protein kinase Sgk1	Homo sapiens (human)	IC50	30.0000	1	1
Serine/threonine-protein kinase TBK1	Homo sapiens (human)	IC50	15.1100	2	2
Serine/threonine-protein kinase WNK2	Homo sapiens (human)	IC50	30.0000	1	1
Short transient receptor potential channel 5	Homo sapiens (human)	IC50	10.0000	1	1
Sialidase	Clostridium perfringens	IC50	4.3000	1	1
Sialidase-2	Homo sapiens (human)	IC50	130.0000	1	1
Sigma non-opioid intracellular receptor 1	Cavia porcellus (domestic guinea pig)	Ki	7.9000	1	1
Sodium channel protein type 5 subunit alpha	Homo sapiens (human)	IC50	27.8298	2	2
Sodium-dependent noradrenaline transporter	Homo sapiens (human)	IC50	3.7870	1	1
Sodium-dependent noradrenaline transporter	Homo sapiens (human)	Ki	3.7560	1	1
Soluble acetylcholine receptor	Aplysia californica (California sea hare)	Ki	1.0466	3	3
Solute carrier family 22 member 1	Rattus norvegicus (Norway rat)	Ki	64.3000	1	1
Solute carrier family 22 member 1	Homo sapiens (human)	IC50	6.1000	1	1
Solute carrier family 22 member 2	Rattus norvegicus (Norway rat)	Ki	50.5000	1	1
Solute carrier organic anion transporter family member 1B1	Homo sapiens (human)	IC50	0.5248	1	1
Solute carrier organic anion transporter family member 1B1	Homo sapiens (human)	Ki	0.2900	1	1
Solute carrier organic anion transporter family member 1B3	Homo sapiens (human)	IC50	0.5495	1	1
Solute carrier organic anion transporter family member 1B3	Homo sapiens (human)	Ki	0.4200	1	1
Sortase A	Streptococcus mutans	IC50	10.2000	1	1
STE20-like serine/threonine-protein kinase	Homo sapiens (human)	IC50	5.5000	2	2
Stromelysin-1	Homo sapiens (human)	IC50	16.2000	1	1
Substance-K receptor	Cavia porcellus (domestic guinea pig)	IC50	33.7000	1	1
Substance-P receptor	Cavia porcellus (domestic guinea pig)	IC50	33.7000	1	1
Testis-specific serine/threonine-protein kinase 2	Homo sapiens (human)	IC50	30.0000	1	1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1	Homo sapiens (human)	IC50	0.9000	1	1
Thioredoxin reductase 1, cytoplasmic	Homo sapiens (human)	IC50	40.4667	3	3
Thioredoxin reductase 2, mitochondrial	Homo sapiens (human)	IC50	40.4667	3	3
Thioredoxin reductase 3	Homo sapiens (human)	IC50	40.4667	3	3
Thiosulfate sulfurtransferase	Homo sapiens (human)	IC50	56.0000	1	1
Thyroid hormone receptor beta	Rattus norvegicus (Norway rat)	Ki	14.0000	1	1
Tissue factor	Homo sapiens (human)	IC50	0.0132	1	1
toll-like receptor 9	Homo sapiens (human)	IC50	8.3620	1	1
TPA: protein transporter TIM10	Saccharomyces cerevisiae S288C	IC50	19.7000	1	1
TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)	IC50	5.5000	2	2
Transcription factor GATA-4	Mus musculus (house mouse)	IC50	22.0000	1	1
Translocator protein	Rattus norvegicus (Norway rat)	IC50	0.0390	1	2
Translocator protein	Rattus norvegicus (Norway rat)	Ki	0.5063	2	4
Transporter	Rattus norvegicus (Norway rat)	Ki	2.7500	2	2
Transthyretin	Homo sapiens (human)	IC50	6.4000	1	1
Tyrosinase	Homo sapiens (human)	IC50	32.5000	2	2
Tyrosine-protein kinase ABL1	Homo sapiens (human)	IC50	18.7054	5	5
Tyrosine-protein kinase ABL1	Mus musculus (house mouse)	IC50	14.6000	1	1
Tyrosine-protein kinase ABL2	Homo sapiens (human)	IC50	30.0000	1	1
Tyrosine-protein kinase Blk	Homo sapiens (human)	IC50	15.5000	2	2
Tyrosine-protein kinase BTK	Homo sapiens (human)	IC50	30.0000	1	1
Tyrosine-protein kinase CSK	Homo sapiens (human)	IC50	30.0000	1	1
Tyrosine-protein kinase Fer	Homo sapiens (human)	IC50	17.0000	1	1
Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)	IC50	30.0000	1	1
Tyrosine-protein kinase Fgr	Homo sapiens (human)	IC50	8.5000	1	1
Tyrosine-protein kinase FRK	Homo sapiens (human)	IC50	1.0000	1	1
Tyrosine-protein kinase Fyn	Homo sapiens (human)	IC50	15.8428	5	5
Tyrosine-protein kinase HCK	Homo sapiens (human)	IC50	6.9633	3	3
Tyrosine-protein kinase JAK2	Homo sapiens (human)	IC50	30.0000	1	1
Tyrosine-protein kinase JAK3	Homo sapiens (human)	IC50	30.0000	1	1
Tyrosine-protein kinase Lck	Homo sapiens (human)	IC50	10.1660	6	6
Tyrosine-protein kinase Lyn	Homo sapiens (human)	IC50	0.9600	1	1
Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)	IC50	1.0000	1	1
Tyrosine-protein kinase receptor UFO	Homo sapiens (human)	IC50	10.0060	3	3
Tyrosine-protein kinase SYK	Homo sapiens (human)	IC50	20.6667	3	3
Tyrosine-protein kinase Yes	Homo sapiens (human)	IC50	8.9000	1	1
Tyrosine-protein kinase Yes	Homo sapiens (human)	Ki	2.3800	1	1
Tyrosine-protein kinase ZAP-70	Homo sapiens (human)	IC50	25.0000	2	2
Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens (human)	IC50	32.9000	2	2
Tyrosine-protein phosphatase non-receptor type 11	Homo sapiens (human)	IC50	9.6000	2	2
Tyrosine-protein phosphatase non-receptor type 2	Homo sapiens (human)	IC50	20.0000	1	1
Tyrosine-protein phosphatase non-receptor type 6	Homo sapiens (human)	IC50	65.4000	1	1
Tyrosine-protein phosphatase non-receptor type 7	Homo sapiens (human)	IC50	300.0000	1	1
UDP-glucuronosyltransferase 1A1	Homo sapiens (human)	Ki	11.3000	2	2
UDP-glucuronosyltransferase 1A10	Homo sapiens (human)	Ki	121.3000	1	1
UDP-glucuronosyltransferase 1A7	Homo sapiens (human)	Ki	101.0000	1	1
UDP-glucuronosyltransferase 1A8	Homo sapiens (human)	Ki	23.0000	2	2
UDP-glucuronosyltransferase 1A9	Homo sapiens (human)	Ki	534.0000	1	1
Urease subunit alpha	Helicobacter pylori 26695	IC50	67.7000	2	2
Urease subunit beta	Helicobacter pylori 26695	IC50	67.7000	2	2
Vascular endothelial growth factor receptor 1	Homo sapiens (human)	IC50	0.3354	4	4
Vascular endothelial growth factor receptor 1	Homo sapiens (human)	Ki	0.0020	1	1
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	GI50	0.0330	1	1
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	IC50	3.7105	58	60
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	Ki	0.0075	4	4
Vascular endothelial growth factor receptor 3	Homo sapiens (human)	IC50	0.1395	2	2
Vascular endothelial growth factor receptor 3	Homo sapiens (human)	Ki	0.0170	1	1
Vitamin D3 receptor	Bos taurus (cattle)	IC50	0.0000	1	1
Vitamin D3 receptor	Homo sapiens (human)	IC50	0.3401	19	19
Vitamin D3 receptor	Rattus norvegicus (Norway rat)	Ki	0.0001	11	11
Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)	IC50	104.1196	3	3
Voltage-dependent L-type calcium channel subunit alpha-1C	Rattus norvegicus (Norway rat)	IC50	100.0000	1	1
Voltage-dependent L-type calcium channel subunit alpha-1D	Rattus norvegicus (Norway rat)	IC50	100.0000	1	1
Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)	IC50	33.4000	1	1
Voltage-dependent L-type calcium channel subunit alpha-1F	Homo sapiens (human)	IC50	33.4000	1	1
Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)	IC50	33.4000	1	1
Voltage-dependent L-type calcium channel subunit alpha-1S	Rattus norvegicus (Norway rat)	IC50	100.0000	1	1
Xanthine dehydrogenase/oxidase	Bos taurus (cattle)	IC50	10.2000	1	1
Xanthine dehydrogenase/oxidase	Homo sapiens (human)	IC50	6.6300	3	3
Xanthine dehydrogenase/oxidase	Bos taurus (cattle)	Ki	1.9000	1	1
Xanthine dehydrogenase/oxidase	Homo sapiens (human)	Ki	2.9000	1	1

Activation Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	Homo sapiens (human)	EC50	0.0030	1	1
26S proteasome regulatory subunit 6B	Homo sapiens (human)	Kd	30.0000	1	2
3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)	Kd	6.1000	3	5
5-hydroxytryptamine receptor 4	Homo sapiens (human)	EC50	10.0000	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)	Kd	2.6550	6	8
5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)	Kd	4.0534	3	5
5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)	Kd	1.1400	1	1
5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)	Kd	1.7340	1	1
AarF domain-containing protein kinase 1	Homo sapiens (human)	Kd	30.0000	1	2
Acetylcholine receptor subunit alpha	Homo sapiens (human)	EC50	25.3333	3	3
Acetylcholine receptor subunit alpha	Tetronarce californica (Pacific electric ray)	EC50	60.0000	1	1
Acetylcholine receptor subunit beta	Homo sapiens (human)	EC50	29.0000	3	3
Acetylcholine receptor subunit beta	Tetronarce californica (Pacific electric ray)	EC50	60.0000	1	1
Acetylcholine receptor subunit delta	Homo sapiens (human)	EC50	33.0000	2	2
Acetylcholine receptor subunit delta	Tetronarce californica (Pacific electric ray)	EC50	110.0000	2	2
Acetylcholine receptor subunit epsilon	Homo sapiens (human)	EC50	65.0000	1	1
Acetylcholine receptor subunit gamma	Homo sapiens (human)	EC50	33.0000	2	2
Acetylcholine receptor subunit gamma	Tetronarce californica (Pacific electric ray)	EC50	60.0000	1	1
Acetylcholine-binding protein	Lymnaea stagnalis (great pond snail)	Kd	0.2931	3	5
Actin-related protein 2	Homo sapiens (human)	Kd	30.0000	1	1
Actin-related protein 3	Homo sapiens (human)	Kd	30.0000	1	1
Activated CDC42 kinase 1	Homo sapiens (human)	Kd	11.6667	4	6
Activin receptor type-1	Homo sapiens (human)	Kd	15.7143	4	7
Activin receptor type-1B	Homo sapiens (human)	Kd	13.3333	4	6
Activin receptor type-2A	Homo sapiens (human)	Kd	10.0000	3	5
Activin receptor type-2B	Homo sapiens (human)	Kd	13.3333	4	6
Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)	Kd	30.0000	1	1
Adenine phosphoribosyltransferase	Homo sapiens (human)	Kd	30.0000	1	1
Adenosine kinase	Homo sapiens (human)	Kd	30.0000	1	1
Adenosine receptor A1	Homo sapiens (human)	Kd	12.0000	1	1
Adenosine receptor A2a	Homo sapiens (human)	EC50	28.2000	1	1
Adenosine receptor A2a	Homo sapiens (human)	Kd	2.8115	3	3
Adenylate kinase 2, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	1
ADP/ATP translocase 2	Homo sapiens (human)	Kd	30.0000	1	1
ADP/ATP translocase 3	Homo sapiens (human)	Kd	30.0000	1	1
ALK tyrosine kinase receptor	Homo sapiens (human)	Kd	4.1020	3	5
Alpha-synuclein	Homo sapiens (human)	Kd	3.5000	4	4
Alpha-tocopherol transfer protein	Homo sapiens (human)	Kd	2.4200	1	1
Amyloid-beta precursor protein	Homo sapiens (human)	EC50	8.4100	1	1
Angiopoietin-1 receptor	Homo sapiens (human)	Kd	5.0085	4	6
Angiotensin-converting enzyme 2	Homo sapiens (human)	EC50	10.6000	1	1
Ankyrin repeat and protein kinase domain-containing protein 1	Homo sapiens (human)	Kd	0.5860	3	5
AP2-associated protein kinase 1	Homo sapiens (human)	Kd	2.0583	8	10
ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)	Kd	30.0000	1	1
ATP-dependent RNA helicase DDX1	Homo sapiens (human)	Kd	30.0000	1	1
ATP-dependent RNA helicase DDX3X	Homo sapiens (human)	Kd	30.0000	1	1
ATP-dependent RNA helicase DDX42	Homo sapiens (human)	Kd	30.0000	1	1
ATP-dependent RNA helicase DHX30	Homo sapiens (human)	Kd	30.0000	1	1
ATP-dependent translocase ABCB1	Homo sapiens (human)	EC50	0.5240	1	1
Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)	Kd	13.3333	4	6
Atypical kinase COQ8B, mitochondrial	Homo sapiens (human)	Kd	10.0000	3	5
Aurora kinase A	Homo sapiens (human)	Kd	8.8143	5	7
Aurora kinase B	Homo sapiens (human)	Kd	3.8262	4	6
Aurora kinase C	Homo sapiens (human)	Kd	3.0400	5	7
BDNF/NT-3 growth factors receptor	Homo sapiens (human)	Kd	0.5820	3	5
Beta-adrenergic receptor kinase 1	Homo sapiens (human)	Kd	30.0000	1	1
BMP-2-inducible protein kinase	Homo sapiens (human)	Kd	2.5224	6	8
Bone morphogenetic protein receptor type-1A	Homo sapiens (human)	Kd	13.3333	4	6
Bone morphogenetic protein receptor type-1B	Homo sapiens (human)	Kd	13.1000	3	4
Bone morphogenetic protein receptor type-2	Homo sapiens (human)	Kd	4.0530	4	6
Breakpoint cluster region protein	Homo sapiens (human)	EC50	1.0000	1	1
Breakpoint cluster region protein	Homo sapiens (human)	Kd	30.0000	1	1
Bromodomain-containing protein 7	Homo sapiens (human)	Kd	11.0000	1	1
Bromodomain-containing protein 9	Homo sapiens (human)	Kd	17.0000	1	1
calcineurin A1, putative	Candida dubliniensis CD36	EC50	180.0000	1	1
Calcium-dependent protein kinase 1	Plasmodium falciparum 3D7	Kd	5.6500	1	2
Calcium/calmodulin-dependent protein kinase kinase 1	Homo sapiens (human)	Kd	3.6933	4	6
Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)	Kd	8.6143	5	7
Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)	Kd	4.1517	4	6
Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)	Kd	3.7717	4	6
Calcium/calmodulin-dependent protein kinase type 1G	Homo sapiens (human)	Kd	4.3740	3	5
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)	Kd	2.9971	5	7
Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)	Kd	4.5667	4	6
Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)	Kd	7.4800	5	7
Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)	Kd	2.7698	7	9
Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)	Kd	4.2733	4	6
cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)	Kd	14.0000	3	5
cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)	Kd	13.3333	4	6
cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)	Kd	30.0000	1	1
cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)	Kd	13.3333	4	6
cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)	Kd	30.0000	1	1
Casein kinase I isoform alpha	Homo sapiens (human)	Kd	4.4970	3	4
Casein kinase I isoform alpha-like	Homo sapiens (human)	Kd	5.2750	2	4
Casein kinase I isoform delta	Homo sapiens (human)	Kd	3.4857	4	6
Casein kinase I isoform epsilon	Homo sapiens (human)	Kd	3.4812	4	6
Casein kinase I isoform gamma-1	Homo sapiens (human)	Kd	4.3607	4	6
Casein kinase I isoform gamma-2	Homo sapiens (human)	Kd	8.3883	4	6
Casein kinase I isoform gamma-3	Homo sapiens (human)	Kd	3.9443	4	6
Casein kinase II subunit alpha	Homo sapiens (human)	Kd	4.2124	3	5
Casein kinase II subunit alpha'	Homo sapiens (human)	Kd	4.0168	4	6
Cell division control protein 2 homolog	Plasmodium falciparum 3D7	Kd	10.0000	1	2
Cell division cycle 7-related protein kinase	Homo sapiens (human)	Kd	30.0000	1	1
cGMP-dependent protein kinase 1	Homo sapiens (human)	Kd	13.3333	4	6
cGMP-dependent protein kinase 2	Homo sapiens (human)	Kd	10.0000	3	5
Chain A, p38 MAP kinase	Homo sapiens (human)	Kd	0.0001	1	2
Chain A, Transthyretin	Homo sapiens (human)	Kd	0.1000	1	5
Chain A, Vitamin D Nuclear Receptor	Homo sapiens (human)	Kd	0.0006	1	1
Chain B, Transthyretin	Homo sapiens (human)	Kd	0.1000	1	2
Choline-phosphate cytidylyltransferase A	Homo sapiens (human)	Kd	30.0000	1	1
Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)	Kd	30.0000	1	1
Citron Rho-interacting kinase	Homo sapiens (human)	Kd	7.6500	4	6
Cyclin-dependent kinase 1	Homo sapiens (human)	Kd	30.0000	1	1
Cyclin-dependent kinase 10	Homo sapiens (human)	Kd	30.0000	1	1
Cyclin-dependent kinase 11A	Homo sapiens (human)	Kd	10.0000	3	5
Cyclin-dependent kinase 11B	Homo sapiens (human)	Kd	10.0000	3	5
Cyclin-dependent kinase 12	Homo sapiens (human)	Kd	30.0000	1	1
Cyclin-dependent kinase 13	Homo sapiens (human)	Kd	13.7000	2	3
Cyclin-dependent kinase 14	Homo sapiens (human)	Kd	4.1620	3	5
Cyclin-dependent kinase 15	Homo sapiens (human)	Kd	10.0000	2	3
Cyclin-dependent kinase 16	Homo sapiens (human)	Kd	2.8829	6	8
Cyclin-dependent kinase 17	Homo sapiens (human)	Kd	4.4133	4	6
Cyclin-dependent kinase 18	Homo sapiens (human)	Kd	9.1833	4	6
Cyclin-dependent kinase 19	Homo sapiens (human)	Kd	6.0800	3	5
Cyclin-dependent kinase 2	Homo sapiens (human)	Kd	12.8571	5	7
Cyclin-dependent kinase 3	Homo sapiens (human)	Kd	8.5040	4	6
Cyclin-dependent kinase 4	Homo sapiens (human)	Kd	11.6400	3	5
Cyclin-dependent kinase 6	Homo sapiens (human)	Kd	30.0000	1	1
Cyclin-dependent kinase 7	Homo sapiens (human)	Kd	2.5487	4	6
Cyclin-dependent kinase 8	Homo sapiens (human)	Kd	6.0880	3	5
Cyclin-dependent kinase 9	Homo sapiens (human)	Kd	13.3333	4	6
Cyclin-dependent kinase-like 1	Homo sapiens (human)	Kd	10.0000	1	2
Cyclin-dependent kinase-like 2	Homo sapiens (human)	Kd	4.0667	2	3
Cyclin-dependent kinase-like 3	Homo sapiens (human)	Kd	10.0000	2	3
Cyclin-dependent kinase-like 5	Homo sapiens (human)	Kd	18.0000	3	5
Cyclin-dependent-like kinase 5	Homo sapiens (human)	Kd	8.7557	5	7
Cyclin-G-associated kinase	Homo sapiens (human)	Kd	2.4008	7	9
Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)	Kd	30.0000	1	1
Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	1
Cytochrome P450 2A13	Homo sapiens (human)	Kd	54.0000	1	1
Cytochrome P450 2A6	Homo sapiens (human)	Kd	470.0000	1	1
Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)	Kd	10.0000	3	5
dCTP pyrophosphatase 1	Homo sapiens (human)	Kd	30.0000	1	1
Death-associated protein kinase 1	Homo sapiens (human)	Kd	4.0720	3	5
Death-associated protein kinase 2	Homo sapiens (human)	Kd	3.0557	5	7
Death-associated protein kinase 3	Homo sapiens (human)	Kd	3.4184	6	9
Delta(24)-sterol reductase	Homo sapiens (human)	Kd	30.0000	1	2
Deoxycytidine kinase	Homo sapiens (human)	Kd	30.0000	1	1
Discoidin domain-containing receptor 2	Homo sapiens (human)	Kd	5.8948	7	9
DNA damage-binding protein 1	Homo sapiens (human)	EC50	0.0090	1	1
DNA replication licensing factor MCM4	Homo sapiens (human)	Kd	30.0000	1	1
DNA topoisomerase 2-alpha	Homo sapiens (human)	Kd	30.0000	1	1
DNA topoisomerase 2-beta	Homo sapiens (human)	Kd	30.0000	1	1
DNA-binding protein Ikaros	Homo sapiens (human)	EC50	0.0455	1	2
DnaJ homolog subfamily A member 1	Homo sapiens (human)	Kd	30.0000	1	1
Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)	Kd	5.6500	1	2
Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)	Kd	3.8283	4	6
Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)	Kd	3.6678	4	6
Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)	Kd	11.9500	4	6
Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)	Kd	8.1400	3	5
Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)	Kd	4.5237	2	3
Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)	Kd	12.5333	4	6
Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)	Kd	10.0000	1	2
Dual specificity protein kinase CLK1	Homo sapiens (human)	Kd	2.3031	7	9
Dual specificity protein kinase CLK2	Homo sapiens (human)	Kd	2.3758	7	9
Dual specificity protein kinase CLK3	Homo sapiens (human)	Kd	13.3333	4	6
Dual specificity protein kinase CLK4	Homo sapiens (human)	Kd	5.5862	7	9
Dual specificity protein kinase TTK	Homo sapiens (human)	Kd	4.2721	6	9
Dual specificity testis-specific protein kinase 1	Homo sapiens (human)	Kd	13.3333	4	6
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)	Kd	3.5188	3	4
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)	Kd	5.3800	3	5
Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)	Kd	3.7867	2	3
Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	1
Egl nine homolog 1	Homo sapiens (human)	EC50	50.0000	1	1
eIF-2-alpha kinase GCN2	Homo sapiens (human)	Kd	4.1080	3	5
EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)	Kd	30.0000	1	1
Electron transfer flavoprotein subunit beta	Homo sapiens (human)	Kd	30.0000	1	1
Elongation factor Tu, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	1
Ephrin type-A receptor 1	Homo sapiens (human)	Kd	13.2667	4	6
Ephrin type-A receptor 2	Homo sapiens (human)	Kd	10.7857	5	7
Ephrin type-A receptor 3	Homo sapiens (human)	Kd	1.4400	4	6
Ephrin type-A receptor 4	Homo sapiens (human)	Kd	9.9571	5	7
Ephrin type-A receptor 5	Homo sapiens (human)	Kd	7.6500	5	8
Ephrin type-A receptor 6	Homo sapiens (human)	Kd	1.3300	4	7
Ephrin type-A receptor 7	Homo sapiens (human)	Kd	4.5067	6	9
Ephrin type-A receptor 8	Homo sapiens (human)	Kd	5.1133	4	6
Ephrin type-B receptor 1	Homo sapiens (human)	Kd	2.1700	5	8
Ephrin type-B receptor 2	Homo sapiens (human)	Kd	10.1467	4	6
Ephrin type-B receptor 3	Homo sapiens (human)	Kd	13.3333	4	6
Ephrin type-B receptor 4	Homo sapiens (human)	Kd	13.1625	5	8
Ephrin type-B receptor 6	Homo sapiens (human)	Kd	10.4625	3	4
Epidermal growth factor receptor	Homo sapiens (human)	Kd	8.6049	29	51
Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)	Kd	4.7507	6	8
Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)	Kd	16.6667	2	3
Eukaryotic translation initiation factor 5B	Homo sapiens (human)	Kd	30.0000	1	1
Exosome RNA helicase MTR4	Homo sapiens (human)	Kd	30.0000	1	1
Ferrochelatase, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	1
Fibroblast growth factor receptor 1	Homo sapiens (human)	Kd	2.2221	5	7
Fibroblast growth factor receptor 2	Homo sapiens (human)	Kd	3.2529	5	7
Fibroblast growth factor receptor 3	Homo sapiens (human)	Kd	4.1245	7	11
Fibroblast growth factor receptor 4	Homo sapiens (human)	Kd	8.4200	3	5
Focal adhesion kinase 1	Homo sapiens (human)	Kd	5.8425	6	8
G protein-coupled receptor kinase 4	Homo sapiens (human)	Kd	3.4267	2	3
G protein-coupled receptor kinase 6	Homo sapiens (human)	Kd	1.6150	1	1
G-protein coupled receptor 35	Homo sapiens (human)	EC50	5.2200	2	2
General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)	Kd	1.2250	1	1
Glycine--tRNA ligase	Homo sapiens (human)	Kd	30.0000	1	1
Glycogen phosphorylase, brain form	Homo sapiens (human)	Kd	30.0000	1	1
Glycogen phosphorylase, liver form	Homo sapiens (human)	Kd	30.0000	1	1
Glycogen synthase kinase-3 alpha	Homo sapiens (human)	Kd	13.3333	4	6
Glycogen synthase kinase-3 beta	Homo sapiens (human)	Kd	13.3333	4	6
glycogen synthase kinase-3 beta isoform 1	Homo sapiens (human)	EC50	3.8120	1	1
Glycoprotein IIb	Oryctolagus cuniculus (rabbit)	EC50	1.5068	1	4
GTP-binding nuclear protein Ran	Homo sapiens (human)	Kd	30.0000	1	1
Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)	Kd	30.0000	1	1
heat shock protein 90	Candida albicans	EC50	120.0330	3	4
Heme oxygenase 2	Homo sapiens (human)	Kd	30.0000	1	1
Hepatocyte growth factor receptor	Homo sapiens (human)	Kd	9.0833	8	12
High affinity nerve growth factor receptor	Homo sapiens (human)	Kd	0.5550	7	10
Homeodomain-interacting protein kinase 1	Homo sapiens (human)	Kd	6.6850	2	3
Homeodomain-interacting protein kinase 2	Homo sapiens (human)	Kd	3.3540	2	3
Homeodomain-interacting protein kinase 3	Homo sapiens (human)	Kd	3.3607	2	3
Homeodomain-interacting protein kinase 4	Homo sapiens (human)	Kd	3.4400	2	3
Hormonally up-regulated neu tumor-associated kinase	Homo sapiens (human)	Kd	3.6667	2	3
Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)	Kd	3.6800	2	3
Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)	Kd	10.0000	2	3
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)	Kd	3.9318	4	6
Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)	Kd	30.0000	1	1
Insulin receptor	Homo sapiens (human)	Kd	6.4825	6	8
Insulin receptor-related protein	Homo sapiens (human)	Kd	4.2580	3	5
Insulin-like growth factor 1 receptor	Homo sapiens (human)	Kd	9.6333	4	6
Integrin beta	Oryctolagus cuniculus (rabbit)	EC50	1.5068	1	4
Integrin-linked protein kinase	Homo sapiens (human)	Kd	30.0000	1	1
Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)	Kd	4.4020	3	5
Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)	Kd	10.0070	3	4
Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)	Kd	8.8033	4	6
Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)	Kd	4.2303	2	3
Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	1
Kappa-type opioid receptor	Cavia porcellus (domestic guinea pig)	EC50	0.0000	1	1
Kelch-like ECH-associated protein 1	Homo sapiens (human)	EC50	5.1100	1	1
large T antigen	Betapolyomavirus macacae	EC50	47.9300	1	1
Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	5.0465	2	4
Leukocyte tyrosine kinase receptor	Homo sapiens (human)	Kd	1.6400	3	5
Leukotriene B4 receptor 1	Homo sapiens (human)	EC50	0.0700	1	1
Leukotriene B4 receptor 2	Homo sapiens (human)	EC50	0.0700	1	1
Leukotriene C4 synthase	Cavia porcellus (domestic guinea pig)	Kd	5.4650	1	2
LIM domain kinase 1	Homo sapiens (human)	Kd	15.7143	4	7
LIM domain kinase 2	Homo sapiens (human)	Kd	13.3333	4	6
Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)	Kd	30.0000	1	1
Lymphocyte antigen 96	Homo sapiens (human)	Kd	379.0000	1	1
Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)	Kd	3.2413	3	5
Macrophage-stimulating protein receptor	Homo sapiens (human)	Kd	15.0000	3	4
MAP kinase-activated protein kinase 2	Homo sapiens (human)	Kd	13.3333	4	6
MAP kinase-activated protein kinase 5	Homo sapiens (human)	Kd	13.3333	4	6
MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	8.0400	3	5
MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	5.0000	4	6
MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)	Kd	3.4910	5	7
MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)	Kd	10.1333	4	6
Mast/stem cell growth factor receptor Kit	Homo sapiens (human)	Kd	1.8561	24	62
Maternal embryonic leucine zipper kinase	Homo sapiens (human)	Kd	3.7338	4	6
Megakaryocyte-associated tyrosine-protein kinase	Homo sapiens (human)	Kd	9.2333	2	3
Membrane-associated progesterone receptor component 1	Homo sapiens (human)	Kd	30.0000	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)	Kd	13.3333	4	6
Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	3.4667	2	3
Midasin	Homo sapiens (human)	Kd	30.0000	1	2
Misshapen-like kinase 1	Homo sapiens (human)	Kd	0.1227	2	3
Mitogen-activated protein kinase 1	Homo sapiens (human)	Kd	13.3333	4	6
Mitogen-activated protein kinase 10	Homo sapiens (human)	Kd	6.8305	6	8
Mitogen-activated protein kinase 11	Homo sapiens (human)	EC50	0.0180	1	1
Mitogen-activated protein kinase 11	Homo sapiens (human)	Kd	6.8586	6	9
Mitogen-activated protein kinase 12	Homo sapiens (human)	EC50	0.0180	1	1
Mitogen-activated protein kinase 12	Homo sapiens (human)	Kd	3.7545	5	8
Mitogen-activated protein kinase 13	Homo sapiens (human)	EC50	0.0180	1	1
Mitogen-activated protein kinase 13	Homo sapiens (human)	Kd	4.0156	3	5
Mitogen-activated protein kinase 14	Homo sapiens (human)	EC50	0.0180	1	1
Mitogen-activated protein kinase 14	Homo sapiens (human)	Kd	2.7284	19	22
Mitogen-activated protein kinase 14	Mus musculus (house mouse)	Kd	0.0001	3	3
Mitogen-activated protein kinase 15	Homo sapiens (human)	Kd	11.0000	4	6
Mitogen-activated protein kinase 3	Homo sapiens (human)	Kd	13.3333	4	6
Mitogen-activated protein kinase 4	Homo sapiens (human)	Kd	10.0000	3	5
Mitogen-activated protein kinase 6	Homo sapiens (human)	Kd	10.0000	3	5
Mitogen-activated protein kinase 7	Homo sapiens (human)	Kd	13.3167	4	6
Mitogen-activated protein kinase 8	Homo sapiens (human)	Kd	13.1833	4	6
Mitogen-activated protein kinase 9	Homo sapiens (human)	Kd	6.5531	6	8
Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)	Kd	15.0000	3	4
Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)	Kd	10.0000	3	5
Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)	Kd	4.4995	4	6
Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)	Kd	5.0500	1	2
Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)	Kd	3.3967	2	3
Mitogen-activated protein kinase kinase kinase 15	Homo sapiens (human)	Kd	4.2000	2	3
Mitogen-activated protein kinase kinase kinase 19	Homo sapiens (human)	Kd	3.3447	2	3
Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)	Kd	3.1252	3	4
Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)	Kd	10.2867	4	6
Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)	Kd	3.4260	3	4
Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)	Kd	11.1571	5	7
Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)	Kd	13.3333	4	6
Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)	Kd	15.0000	3	4
Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)	Kd	0.1120	2	3
Mitogen-activated protein kinase kinase kinase 9	Homo sapiens (human)	Kd	6.0400	3	5
Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)	Kd	3.3828	4	6
Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)	Kd	12.5082	3	4
Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)	Kd	3.5113	4	6
Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)	Kd	0.1447	4	6
Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)	Kd	2.6839	6	8
Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)	Kd	3.5070	1	1
Multifunctional protein ADE2	Homo sapiens (human)	Kd	30.0000	1	1
Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)	Kd	1.0540	3	5
Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)	Kd	2.8944	5	7
Myosin light chain kinase 3	Homo sapiens (human)	Kd	13.3410	2	3
Myosin light chain kinase family member 4	Homo sapiens (human)	Kd	4.0090	3	5
Myosin light chain kinase, smooth muscle	Gallus gallus (chicken)	Kd	5.0115	1	2
Myosin light chain kinase, smooth muscle	Homo sapiens (human)	Kd	10.1079	5	8
Myosin-10	Homo sapiens (human)	Kd	30.0000	1	1
Myosin-14	Homo sapiens (human)	Kd	30.0000	1	1
Myosin-IIIa	Homo sapiens (human)	Kd	8.6200	3	5
Myosin-IIIb	Homo sapiens (human)	Kd	6.7000	3	5
Myotonin-protein kinase	Homo sapiens (human)	Kd	10.0000	3	5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)	Kd	30.0000	1	2
Neuronal acetylcholine receptor subunit alpha-10	Rattus norvegicus (Norway rat)	EC50	40.6667	2	3
Neuronal acetylcholine receptor subunit alpha-10	Rattus norvegicus (Norway rat)	Kd	14,352.0000	3	3
Neuronal acetylcholine receptor subunit alpha-2	Rattus norvegicus (Norway rat)	EC50	35.5000	2	2
Neuronal acetylcholine receptor subunit alpha-2	Rattus norvegicus (Norway rat)	Kd	14,352.0000	3	3
Neuronal acetylcholine receptor subunit alpha-3	Homo sapiens (human)	EC50	21.3260	14	15
Neuronal acetylcholine receptor subunit alpha-3	Rattus norvegicus (Norway rat)	EC50	30.2517	7	8
Neuronal acetylcholine receptor subunit alpha-3	Rattus norvegicus (Norway rat)	Kd	14,352.0000	3	3
Neuronal acetylcholine receptor subunit alpha-4	Homo sapiens (human)	EC50	3.1424	20	24
Neuronal acetylcholine receptor subunit alpha-4	Mus musculus (house mouse)	EC50	0.7222	1	2
Neuronal acetylcholine receptor subunit alpha-4	Rattus norvegicus (Norway rat)	EC50	10.7398	12	12
Neuronal acetylcholine receptor subunit alpha-4	Rattus norvegicus (Norway rat)	Kd	14,352.0000	3	3
Neuronal acetylcholine receptor subunit alpha-5	Homo sapiens (human)	EC50	30.0000	1	1
Neuronal acetylcholine receptor subunit alpha-5	Rattus norvegicus (Norway rat)	EC50	35.5000	2	2
Neuronal acetylcholine receptor subunit alpha-5	Rattus norvegicus (Norway rat)	Kd	14,352.0000	3	3
Neuronal acetylcholine receptor subunit alpha-6	Homo sapiens (human)	EC50	0.1270	1	1
Neuronal acetylcholine receptor subunit alpha-6	Rattus norvegicus (Norway rat)	EC50	35.5000	2	2
Neuronal acetylcholine receptor subunit alpha-6	Rattus norvegicus (Norway rat)	Kd	14,352.0000	3	3
Neuronal acetylcholine receptor subunit alpha-7	Homo sapiens (human)	EC50	55.2158	6	6
Neuronal acetylcholine receptor subunit alpha-7	Rattus norvegicus (Norway rat)	EC50	3,948.0836	10	11
Neuronal acetylcholine receptor subunit alpha-7	Homo sapiens (human)	Kd	0.0011	1	1
Neuronal acetylcholine receptor subunit alpha-7	Rattus norvegicus (Norway rat)	Kd	14,352.0000	3	3
Neuronal acetylcholine receptor subunit alpha-9	Rattus norvegicus (Norway rat)	EC50	35.5000	2	2
Neuronal acetylcholine receptor subunit alpha-9	Rattus norvegicus (Norway rat)	Kd	14,352.0000	3	3
Neuronal acetylcholine receptor subunit beta-2	Homo sapiens (human)	EC50	9.3127	23	27
Neuronal acetylcholine receptor subunit beta-2	Mus musculus (house mouse)	EC50	0.7222	1	2
Neuronal acetylcholine receptor subunit beta-2	Rattus norvegicus (Norway rat)	EC50	10.7398	12	12
Neuronal acetylcholine receptor subunit beta-2	Rattus norvegicus (Norway rat)	Kd	14,352.0000	3	3
Neuronal acetylcholine receptor subunit beta-3	Homo sapiens (human)	EC50	10.5635	2	2
Neuronal acetylcholine receptor subunit beta-3	Rattus norvegicus (Norway rat)	EC50	35.5000	2	2
Neuronal acetylcholine receptor subunit beta-3	Rattus norvegicus (Norway rat)	Kd	14,352.0000	3	3
Neuronal acetylcholine receptor subunit beta-4	Homo sapiens (human)	EC50	13.6576	14	15
Neuronal acetylcholine receptor subunit beta-4	Rattus norvegicus (Norway rat)	EC50	30.2517	7	8
Neuronal acetylcholine receptor subunit beta-4	Rattus norvegicus (Norway rat)	Kd	14,352.0000	3	3
Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)	Kd	8.6733	4	6
Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)	Kd	7.2800	6	9
NT-3 growth factor receptor	Homo sapiens (human)	Kd	3.1360	3	5
NUAK family SNF1-like kinase 1	Homo sapiens (human)	Kd	4.0288	3	5
NUAK family SNF1-like kinase 2	Homo sapiens (human)	Kd	8.4083	4	6
Nuclear factor erythroid 2-related factor 2	Homo sapiens (human)	EC50	13.0550	2	2
Nucleolar GTP-binding protein 1	Homo sapiens (human)	Kd	30.0000	1	1
Obg-like ATPase 1	Homo sapiens (human)	Kd	30.0000	1	1
Oxoeicosanoid receptor 1	Homo sapiens (human)	EC50	0.1135	2	2
Palmitoleoyl-protein carboxylesterase NOTUM	Homo sapiens (human)	Kd	6,800.0000	1	1
PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)	Kd	30.0000	1	1
Peripheral plasma membrane protein CASK	Homo sapiens (human)	Kd	10.0000	1	2
Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)	Kd	30.0000	1	1
Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)	Kd	30.0000	1	1
Peroxisome proliferator-activated receptor gamma	Mus musculus (house mouse)	EC50	2.3000	1	1
Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)	Kd	30.0000	1	1
Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)	Kd	30.0000	1	1
Phosphatidylinositol 4-kinase beta	Homo sapiens (human)	Kd	10.0000	2	3
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)	Kd	10.0000	2	3
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	Homo sapiens (human)	Kd	10.0000	2	3
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)	Kd	7.2400	3	5
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)	Kd	10.0000	1	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)	Kd	10.0000	21	33
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)	Kd	10.0000	2	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)	Kd	10.0000	2	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)	Kd	10.0000	2	3
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)	Kd	30.0000	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)	Kd	4.0234	3	5
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)	Kd	16.6667	2	3
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)	Kd	2.5946	6	8
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	Homo sapiens (human)	Kd	2.8795	5	7
Platelet-derived growth factor receptor alpha	Homo sapiens (human)	Kd	0.4805	3	5
Platelet-derived growth factor receptor beta	Homo sapiens (human)	Kd	0.3561	6	9
Poly [ADP-ribose] polymerase tankyrase-2	Homo sapiens (human)	Kd	8.9000	1	1
Polyunsaturated fatty acid 5-lipoxygenase	Homo sapiens (human)	EC50	0.0700	1	1
POsterior Segregation	Caenorhabditis elegans	EC50	60.3740	1	1
Potassium channel subfamily K member 2	Homo sapiens (human)	EC50	486.0000	1	1
Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)	Kd	30.0000	1	1
Procathepsin L	Homo sapiens (human)	EC50	10.6000	1	1
Prolyl hydroxylase EGLN2	Homo sapiens (human)	EC50	50.0000	1	1
Prolyl hydroxylase EGLN3	Homo sapiens (human)	EC50	50.0000	1	1
Prostaglandin G/H synthase 2	Homo sapiens (human)	Kd	5.0175	1	2
Protein cereblon	Homo sapiens (human)	EC50	0.0418	3	5
Protein delta homolog 1	Homo sapiens (human)	Kd	0.1000	1	1
Protein kinase C alpha type	Homo sapiens (human)	Kd	15.3333	3	3
Protein kinase C beta type	Homo sapiens (human)	Kd	30.0000	1	1
Protein kinase C delta type	Homo sapiens (human)	Kd	13.3333	4	6
Protein kinase C epsilon type	Homo sapiens (human)	Kd	10.0000	3	5
Protein kinase C eta type	Homo sapiens (human)	Kd	8.3750	4	6
Protein kinase C iota type	Homo sapiens (human)	Kd	16.6667	2	3
Protein kinase C theta type	Homo sapiens (human)	Kd	10.4833	4	6
Protein kinase C zeta type	Homo sapiens (human)	Kd	30.0000	1	1
Protein polybromo-1	Homo sapiens (human)	Kd	12.9000	1	1
Protein-tyrosine kinase 2-beta	Homo sapiens (human)	Kd	8.8894	4	7
Protein-tyrosine kinase 6	Homo sapiens (human)	Kd	12.4333	4	6
Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)	Kd	1.2727	11	17
Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)	Kd	10.0000	3	5
Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)	Kd	8.4857	5	7
Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)	Kd	30.0000	1	1
Pyridoxal kinase	Homo sapiens (human)	Kd	6.0210	1	1
Rab-like protein 3	Homo sapiens (human)	Kd	30.0000	1	1
RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)	Kd	13.3333	4	6
RAC-beta serine/threonine-protein kinase	Homo sapiens (human)	Kd	9.6833	4	6
RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)	Kd	13.3333	4	6
RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)	Kd	10.0000	3	5
Ras-related protein Rab-10	Homo sapiens (human)	Kd	30.0000	1	1
Ras-related protein Rab-27A	Homo sapiens (human)	Kd	30.0000	1	2
Ras-related protein Rab-6A	Homo sapiens (human)	Kd	30.0000	1	1
Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)	Kd	10.0000	3	5
Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)	Kd	10.0000	2	3
Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)	Kd	10.0000	2	3
Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	3.5800	4	6
Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	12.6333	4	6
Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)	Kd	30.0000	1	1
Receptor-interacting serine/threonine-protein kinase 4	Homo sapiens (human)	Kd	4.7333	2	3
Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)	Kd	2.1011	25	38
Replicase polyprotein 1a	Severe acute respiratory syndrome-related coronavirus	EC50	10.6000	2	2
Replicase polyprotein 1ab	Betacoronavirus England 1	EC50	10.6000	1	1
Replicase polyprotein 1ab	Human coronavirus 229E	EC50	10.6000	2	2
Replicase polyprotein 1ab	Severe acute respiratory syndrome coronavirus 2	EC50	10.3000	2	2
Replicase polyprotein 1ab	Severe acute respiratory syndrome-related coronavirus	EC50	10.4000	3	3
Retinoic acid receptor RXR-alpha	Homo sapiens (human)	EC50	0.0016	1	1
Rho-associated protein kinase 1	Homo sapiens (human)	Kd	10.2300	3	4
Rho-associated protein kinase 2	Homo sapiens (human)	Kd	10.0700	3	4
Rhodopsin kinase GRK1	Homo sapiens (human)	Kd	3.5267	2	3
Rhodopsin kinase GRK7	Homo sapiens (human)	Kd	3.4533	2	3
Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)	Kd	4.8755	7	11
Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)	Kd	4.8898	8	12
Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)	Kd	3.1207	6	8
Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)	Kd	4.5367	7	11
Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)	Kd	4.1150	9	13
Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)	Kd	9.7455	7	11
Ribosomal protein S6 kinase beta-1	Homo sapiens (human)	Kd	10.0620	3	4
Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)	Kd	4.0220	1	1
RNA cytidine acetyltransferase	Homo sapiens (human)	Kd	30.0000	1	1
S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)	Kd	30.0000	1	1
Septin-9	Homo sapiens (human)	Kd	30.0000	1	2
Serine/threonine-protein kinase 10	Homo sapiens (human)	Kd	0.5866	5	8
Serine/threonine-protein kinase 16	Homo sapiens (human)	Kd	6.4338	6	8
Serine/threonine-protein kinase 17A	Homo sapiens (human)	Kd	2.8636	5	7
Serine/threonine-protein kinase 17B	Homo sapiens (human)	Kd	2.9671	5	7
Serine/threonine-protein kinase 24	Homo sapiens (human)	Kd	4.0455	4	6
Serine/threonine-protein kinase 25	Homo sapiens (human)	Kd	4.1740	3	5
Serine/threonine-protein kinase 26	Homo sapiens (human)	Kd	3.8757	4	6
Serine/threonine-protein kinase 3	Homo sapiens (human)	Kd	3.7618	4	6
Serine/threonine-protein kinase 3	Mus musculus (house mouse)	Kd	0.1600	1	1
Serine/threonine-protein kinase 32A	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase 32B	Homo sapiens (human)	Kd	10.0000	3	5
Serine/threonine-protein kinase 32C	Homo sapiens (human)	Kd	10.0000	3	5
Serine/threonine-protein kinase 33	Homo sapiens (human)	Kd	4.0102	3	5
Serine/threonine-protein kinase 35	Homo sapiens (human)	Kd	4.2000	2	3
Serine/threonine-protein kinase 36	Homo sapiens (human)	Kd	10.0000	3	5
Serine/threonine-protein kinase 38	Homo sapiens (human)	Kd	3.6067	2	3
Serine/threonine-protein kinase 38-like	Homo sapiens (human)	Kd	7.7729	5	7
Serine/threonine-protein kinase 4	Homo sapiens (human)	Kd	2.6982	6	8
Serine/threonine-protein kinase A-Raf	Homo sapiens (human)	Kd	30.0000	1	1
Serine/threonine-protein kinase ATR	Homo sapiens (human)	Kd	30.0000	1	1
Serine/threonine-protein kinase B-raf	Homo sapiens (human)	Kd	10.4909	7	11
Serine/threonine-protein kinase BRSK1	Homo sapiens (human)	Kd	6.1000	3	5
Serine/threonine-protein kinase BRSK2	Homo sapiens (human)	Kd	4.6600	3	5
Serine/threonine-protein kinase Chk1	Homo sapiens (human)	Kd	4.0323	4	6
Serine/threonine-protein kinase Chk2	Homo sapiens (human)	Kd	3.3390	2	3
Serine/threonine-protein kinase D1	Homo sapiens (human)	Kd	4.1860	3	5
Serine/threonine-protein kinase D2	Homo sapiens (human)	Kd	3.7108	4	6
Serine/threonine-protein kinase D3	Homo sapiens (human)	Kd	3.7475	4	6
Serine/threonine-protein kinase DCLK1	Homo sapiens (human)	Kd	4.2220	3	5
Serine/threonine-protein kinase DCLK2	Homo sapiens (human)	Kd	5.6200	3	5
Serine/threonine-protein kinase DCLK3	Homo sapiens (human)	Kd	4.0660	3	5
Serine/threonine-protein kinase ICK	Homo sapiens (human)	Kd	10.2350	3	4
Serine/threonine-protein kinase LATS1	Homo sapiens (human)	Kd	3.7722	4	6
Serine/threonine-protein kinase LATS2	Homo sapiens (human)	Kd	4.2760	3	5
Serine/threonine-protein kinase MAK	Homo sapiens (human)	Kd	10.0000	2	3
Serine/threonine-protein kinase MARK1	Homo sapiens (human)	Kd	4.7200	3	5
Serine/threonine-protein kinase MARK2	Homo sapiens (human)	Kd	3.4661	5	7
Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)	Kd	13.1333	4	6
Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)	Kd	10.3033	4	6
Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)	Kd	10.4000	4	6
Serine/threonine-protein kinase mTOR	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase N1	Homo sapiens (human)	Kd	8.6883	4	6
Serine/threonine-protein kinase N2	Homo sapiens (human)	Kd	8.9833	4	6
Serine/threonine-protein kinase N3	Homo sapiens (human)	Kd	30.0000	1	1
Serine/threonine-protein kinase Nek1	Homo sapiens (human)	Kd	13.3333	4	6
Serine/threonine-protein kinase Nek11	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase Nek2	Homo sapiens (human)	Kd	6.9000	6	8
Serine/threonine-protein kinase Nek3	Homo sapiens (human)	Kd	16.6667	2	3
Serine/threonine-protein kinase Nek4	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase Nek5	Homo sapiens (human)	Kd	10.0000	3	5
Serine/threonine-protein kinase Nek6	Homo sapiens (human)	Kd	10.0000	3	5
Serine/threonine-protein kinase Nek7	Homo sapiens (human)	Kd	10.3833	4	6
Serine/threonine-protein kinase Nek9	Homo sapiens (human)	Kd	13.3333	4	6
Serine/threonine-protein kinase NIM1	Homo sapiens (human)	Kd	3.9000	2	3
Serine/threonine-protein kinase NLK	Homo sapiens (human)	Kd	10.3333	4	6
Serine/threonine-protein kinase OSR1	Homo sapiens (human)	Kd	3.6867	2	3
Serine/threonine-protein kinase PAK 1	Homo sapiens (human)	Kd	10.0000	3	5
Serine/threonine-protein kinase PAK 2	Homo sapiens (human)	Kd	13.3333	4	6
Serine/threonine-protein kinase PAK 3	Homo sapiens (human)	Kd	4.0096	3	5
Serine/threonine-protein kinase PAK 4	Homo sapiens (human)	Kd	9.4833	4	6
Serine/threonine-protein kinase PAK 5	Homo sapiens (human)	Kd	4.3840	3	5
Serine/threonine-protein kinase PAK 6	Homo sapiens (human)	Kd	5.4400	3	5
Serine/threonine-protein kinase pim-1	Homo sapiens (human)	Kd	13.3333	4	6
Serine/threonine-protein kinase pim-2	Homo sapiens (human)	Kd	9.1667	4	6
Serine/threonine-protein kinase pim-3	Homo sapiens (human)	Kd	5.4400	3	5
Serine/threonine-protein kinase PknB	Mycobacterium tuberculosis H37Rv	Kd	5.0435	1	2
Serine/threonine-protein kinase PLK1	Homo sapiens (human)	Kd	13.3333	4	6
Serine/threonine-protein kinase PLK2	Homo sapiens (human)	Kd	6.4667	2	3
Serine/threonine-protein kinase PLK3	Homo sapiens (human)	Kd	10.0000	3	5
Serine/threonine-protein kinase PLK4	Homo sapiens (human)	Kd	6.4163	6	8
Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)	Kd	3.5933	2	3
Serine/threonine-protein kinase receptor R3	Homo sapiens (human)	Kd	10.0000	3	5
Serine/threonine-protein kinase RIO1	Homo sapiens (human)	Kd	4.0210	3	5
Serine/threonine-protein kinase RIO2	Homo sapiens (human)	Kd	2.5745	3	4
Serine/threonine-protein kinase RIO3	Homo sapiens (human)	Kd	6.2800	3	5
Serine/threonine-protein kinase SBK1	Homo sapiens (human)	Kd	5.1000	1	2
Serine/threonine-protein kinase Sgk3	Homo sapiens (human)	Kd	5.1100	1	2
Serine/threonine-protein kinase SIK1	Homo sapiens (human)	Kd	5.9200	3	5
Serine/threonine-protein kinase SIK2	Homo sapiens (human)	Kd	8.6233	4	6
Serine/threonine-protein kinase SIK3	Homo sapiens (human)	Kd	15.0000	3	4
Serine/threonine-protein kinase STK11	Homo sapiens (human)	Kd	8.3523	4	6
Serine/threonine-protein kinase TAO1	Homo sapiens (human)	Kd	10.3560	4	5
Serine/threonine-protein kinase TAO2	Homo sapiens (human)	Kd	16.6667	2	3
Serine/threonine-protein kinase TAO3	Homo sapiens (human)	Kd	10.1050	3	4
Serine/threonine-protein kinase TBK1	Homo sapiens (human)	Kd	2.9355	3	4
Serine/threonine-protein kinase TNNI3K	Homo sapiens (human)	Kd	10.0000	3	5
Serine/threonine-protein kinase tousled-like 1	Homo sapiens (human)	Kd	4.4440	3	5
Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)	Kd	4.1980	3	5
Serine/threonine-protein kinase ULK1	Homo sapiens (human)	Kd	3.0540	3	4
Serine/threonine-protein kinase ULK2	Homo sapiens (human)	Kd	3.3420	2	3
Serine/threonine-protein kinase ULK3	Homo sapiens (human)	Kd	2.8022	3	4
Serine/threonine-protein kinase ULK3	Mus musculus (house mouse)	Kd	0.1100	1	1
Serine/threonine-protein kinase VRK2	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)	Kd	10.3000	3	4
Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)	Kd	30.0000	1	1
Signal recognition particle receptor subunit alpha	Homo sapiens (human)	Kd	30.0000	1	1
SNF-related serine/threonine-protein kinase	Homo sapiens (human)	Kd	5.3200	1	2
Sodium-dependent dopamine transporter	Rattus norvegicus (Norway rat)	EC50	1.4500	1	1
Sodium-dependent noradrenaline transporter	Homo sapiens (human)	EC50	31.0000	1	1
Sodium/bile acid cotransporter	Homo sapiens (human)	Kd	64.3000	1	1
Spike glycoprotein	Betacoronavirus England 1	EC50	10.6000	1	1
Spike glycoprotein	Severe acute respiratory syndrome-related coronavirus	EC50	10.6000	1	1
SRSF protein kinase 1	Homo sapiens (human)	Kd	4.1500	3	5
SRSF protein kinase 2	Homo sapiens (human)	Kd	4.1140	3	5
SRSF protein kinase 3	Homo sapiens (human)	Kd	3.3727	2	3
STE20-like serine/threonine-protein kinase	Homo sapiens (human)	Kd	0.4333	6	9
STE20-related kinase adapter protein alpha	Homo sapiens (human)	Kd	30.0000	1	1
STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)	Kd	3.4267	2	3
Stimulator of interferon genes protein	Homo sapiens (human)	EC50	40.0283	6	6
Stimulator of interferon genes protein	Homo sapiens (human)	Kd	2.2075	4	4
Stimulator of interferon genes protein	Mus musculus (house mouse)	Kd	0.1100	1	1
Stromelysin-1	Homo sapiens (human)	Kd	25,000.0000	1	1
Structural maintenance of chromosomes protein 1A	Homo sapiens (human)	Kd	30.0000	1	1
Structural maintenance of chromosomes protein 2	Homo sapiens (human)	Kd	30.0000	1	1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	1
Testis-specific serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	7.7800	3	5
TGF-beta receptor type-1	Homo sapiens (human)	Kd	13.3333	4	6
TGF-beta receptor type-2	Homo sapiens (human)	Kd	13.3333	4	6
Thyroid hormone receptor-associated protein 3	Homo sapiens (human)	Kd	30.0000	1	1
TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)	Kd	0.0891	6	9
Transient receptor potential cation channel subfamily A member 1	Homo sapiens (human)	EC50	152,369.0000	2	3
Transient receptor potential cation channel subfamily A member 1	Mus musculus (house mouse)	EC50	10.0000	1	1
Transient receptor potential cation channel subfamily M member 6	Homo sapiens (human)	Kd	10.0000	1	2
Transmembrane prolyl 4-hydroxylase	Homo sapiens (human)	EC50	50.0000	1	1
Transmembrane protease serine 2	Homo sapiens (human)	EC50	10.6000	1	1
Transporter	Rattus norvegicus (Norway rat)	EC50	51.0000	1	1
Transthyretin	Homo sapiens (human)	EC50	8.6000	1	1
Transthyretin	Homo sapiens (human)	Kd	0.0700	1	1
Tubulin alpha-1A chain	Rattus norvegicus (Norway rat)	Kd	10.0000	1	2
Tumor necrosis factor	Homo sapiens (human)	EC50	0.0180	1	1
Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)	Kd	30.0000	1	1
Tyrosine-protein kinase ABL1	Homo sapiens (human)	EC50	1.0000	1	1
Tyrosine-protein kinase ABL1	Homo sapiens (human)	Kd	3.1663	40	90
Tyrosine-protein kinase ABL2	Homo sapiens (human)	Kd	6.5000	5	7
Tyrosine-protein kinase Blk	Homo sapiens (human)	Kd	0.3110	3	5
Tyrosine-protein kinase BTK	Homo sapiens (human)	Kd	12.0167	4	6
Tyrosine-protein kinase CSK	Homo sapiens (human)	Kd	13.3333	4	6
Tyrosine-protein kinase Fer	Homo sapiens (human)	Kd	3.8141	5	7
Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)	Kd	8.8133	4	6
Tyrosine-protein kinase Fgr	Homo sapiens (human)	Kd	2.8635	6	8
Tyrosine-protein kinase FRK	Homo sapiens (human)	Kd	4.3388	6	8
Tyrosine-protein kinase Fyn	Homo sapiens (human)	Kd	7.9229	5	7
Tyrosine-protein kinase HCK	Homo sapiens (human)	Kd	3.9833	5	7
Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)	Kd	4.0078	3	5
Tyrosine-protein kinase JAK1	Homo sapiens (human)	Kd	3.8764	8	11
Tyrosine-protein kinase JAK2	Homo sapiens (human)	Kd	7.4529	5	7
Tyrosine-protein kinase JAK3	Homo sapiens (human)	Kd	4.7200	3	5
Tyrosine-protein kinase Lck	Homo sapiens (human)	Kd	0.8568	5	8
Tyrosine-protein kinase Lyn	Homo sapiens (human)	Kd	1.0882	6	8
Tyrosine-protein kinase Mer	Homo sapiens (human)	Kd	1.4956	3	5
Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)	Kd	4.7833	3	5
Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)	Kd	4.0294	3	5
Tyrosine-protein kinase receptor UFO	Homo sapiens (human)	Kd	4.0054	3	5
Tyrosine-protein kinase Srms	Homo sapiens (human)	Kd	10.0000	3	5
Tyrosine-protein kinase SYK	Homo sapiens (human)	EC50	4.5000	1	1
Tyrosine-protein kinase SYK	Homo sapiens (human)	Kd	13.3333	4	6
Tyrosine-protein kinase Tec	Homo sapiens (human)	Kd	13.3333	4	6
Tyrosine-protein kinase TXK	Homo sapiens (human)	Kd	10.0000	3	5
Tyrosine-protein kinase Yes	Homo sapiens (human)	Kd	1.5940	5	7
Tyrosine-protein kinase ZAP-70	Homo sapiens (human)	Kd	10.0000	3	5
U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)	Kd	30.0000	1	1
UMP-CMP kinase	Homo sapiens (human)	Kd	30.0000	1	1
Uncharacterized aarF domain-containing protein kinase 5	Homo sapiens (human)	Kd	30.0000	1	1
Uncharacterized protein FLJ45252	Homo sapiens (human)	Kd	0.4310	1	1
Uncharacterized serine/threonine-protein kinase SBK3	Homo sapiens (human)	Kd	4.6000	2	3
Vascular endothelial growth factor receptor 1	Homo sapiens (human)	Kd	0.1651	3	5
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	Kd	1.2261	6	9
Vascular endothelial growth factor receptor 3	Homo sapiens (human)	Kd	2.1150	5	8
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	1
Vitamin D-binding protein	Homo sapiens (human)	Kd	0.0240	1	1
Vitamin D3 receptor	Bos taurus (cattle)	EC50	0.0001	2	2
Vitamin D3 receptor	Homo sapiens (human)	EC50	0.0394	36	36
Vitamin D3 receptor	Mus musculus (house mouse)	EC50	0.1000	1	1
Vitamin D3 receptor	Rattus norvegicus (Norway rat)	EC50	0.0002	7	7
Vitamin D3 receptor	Homo sapiens (human)	Kd	0.0001	1	1
Vitamin D3 receptor	Sus scrofa (pig)	Kd	0.0001	1	1
Vitamin D3 receptor A	Danio rerio (zebrafish)	EC50	0.0055	1	1
Vitamin D3 receptor A	Danio rerio (zebrafish)	Kd	1.2000	1	1
Wee1-like protein kinase	Homo sapiens (human)	Kd	8.8833	4	6
Wee1-like protein kinase 2	Homo sapiens (human)	Kd	10.0000	2	3
Zinc finger protein Aiolos	Homo sapiens (human)	EC50	0.0545	1	2
Zinc finger protein mex-5	Caenorhabditis elegans	EC50	31.0000	1	1

Other Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
Adenosine receptor A1	Homo sapiens (human)	Affinity constant	10.0000	1	1
Adenosine receptor A1	Rattus norvegicus (Norway rat)	Kb	8.7000	1	1
Adenosine receptor A1	Homo sapiens (human)	KD hydro	2,500.0000	1	1
Adenosine receptor A2a	Homo sapiens (human)	Affinity constant	10.0000	1	1
Adenosine receptor A2a	Rattus norvegicus (Norway rat)	Kb	13.7000	1	1
Adenosine receptor A2a	Rattus norvegicus (Norway rat)	Ratio	25.0000	1	2
Adenosine receptor A2b	Homo sapiens (human)	Affinity constant	10.0000	1	1
Adenosine receptor A2b	Mus musculus (house mouse)	Kb	16.0000	1	1
Adenosine receptor A2b	Rattus norvegicus (Norway rat)	Ratio	25.0000	1	2
Adenylate cyclase type 1	Homo sapiens (human)	Kb	14.0000	1	1
Amyloid-beta precursor protein	Homo sapiens (human)	DC50	0.7550	2	2
Androgen receptor	Homo sapiens (human)	EC150	18.0000	1	1
Breakpoint cluster region protein	Homo sapiens (human)	DC50	10.0000	1	2
Carbonic anhydrase 1	Homo sapiens (human)	Kinact	284.0000	1	1
Carbonic anhydrase 2	Homo sapiens (human)	Kinact	17.7500	2	2
Carbonic anhydrase 5A, mitochondrial	Homo sapiens (human)	Kinact	0.1030	1	1
Carbonic anhydrase 5B, mitochondrial	Homo sapiens (human)	Kinact	0.0980	1	1
Carbonic anhydrase 9	Homo sapiens (human)	Kinact	23.0000	1	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	Homo sapiens (human)	AC50	29.2700	1	1
Cytochrome P450 1A2	Homo sapiens (human)	ED50	0.0002	1	1
Cytochrome P450 2C9	Homo sapiens (human)	ED50	0.0002	1	2
Cytochrome P450 3A4	Homo sapiens (human)	ED50	0.0002	1	1
DNA-binding protein Ikaros	Homo sapiens (human)	DC50	0.0584	1	2
DNA-binding protein Ikaros	Homo sapiens (human)	fEC50	0.2805	1	2
E3 ubiquitin-protein ligase ZFP91	Homo sapiens (human)	DC50	0.4200	1	1
EWS/FLI fusion protein	Homo sapiens (human)	AbsAC35_uM	40.2500	1	1
Glucocorticoid receptor	Homo sapiens (human)	EC150	18.0000	1	1
Microtubule-associated protein tau	Homo sapiens (human)	DC50	200.0000	1	1
Neuronal acetylcholine receptor subunit alpha-10	Rattus norvegicus (Norway rat)	K app	0.0062	1	3
Neuronal acetylcholine receptor subunit alpha-2	Rattus norvegicus (Norway rat)	K app	0.0062	1	3
Neuronal acetylcholine receptor subunit alpha-3	Rattus norvegicus (Norway rat)	K app	0.0062	1	3
Neuronal acetylcholine receptor subunit alpha-4	Rattus norvegicus (Norway rat)	K app	0.0062	1	3
Neuronal acetylcholine receptor subunit alpha-5	Rattus norvegicus (Norway rat)	K app	0.0062	1	3
Neuronal acetylcholine receptor subunit alpha-6	Rattus norvegicus (Norway rat)	K app	0.0062	1	3
Neuronal acetylcholine receptor subunit alpha-7	Rattus norvegicus (Norway rat)	K app	0.0062	1	3
Neuronal acetylcholine receptor subunit alpha-9	Rattus norvegicus (Norway rat)	K app	0.0062	1	3
Neuronal acetylcholine receptor subunit beta-2	Rattus norvegicus (Norway rat)	K app	0.0062	1	3
Neuronal acetylcholine receptor subunit beta-3	Rattus norvegicus (Norway rat)	K app	0.0062	1	3
Neuronal acetylcholine receptor subunit beta-4	Rattus norvegicus (Norway rat)	K app	0.0062	1	3
Pancreatic triacylglycerol lipase	Sus scrofa (pig)	ED50	10.0000	1	1
Protein cereblon	Homo sapiens (human)	DC50	5.0292	2	4
Protein cereblon	Homo sapiens (human)	fEC50	0.2805	1	2
Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)	INH	0.0566	2	2
Retinoic acid receptor RXR-alpha	Homo sapiens (human)	ED50	4.9000	1	1
Seed linoleate 13S-lipoxygenase-1	Glycine max (soybean)	Km	169.0500	2	2
Seed linoleate 13S-lipoxygenase-1	Glycine max (soybean)	Vmax	0.0105	2	2
Solute carrier family 22 member 1	Homo sapiens (human)	Activity	53.2000	1	1
Transporter	Rattus norvegicus (Norway rat)	K app	0.0062	1	1
Tyrosine-protein kinase ABL1	Homo sapiens (human)	DC50	10.0000	1	2
UDP-glucuronosyltransferase 1A1	Homo sapiens (human)	Km	28.7500	2	2
UDP-glucuronosyltransferase 1A10	Homo sapiens (human)	Km	10.3000	1	1
UDP-glucuronosyltransferase 1A7	Homo sapiens (human)	Km	9.4000	1	1
UDP-glucuronosyltransferase 1A8	Homo sapiens (human)	Km	79.2000	2	2
UDP-glucuronosyltransferase 1A9	Homo sapiens (human)	Km	5.0000	1	1
Vasopressin V2 receptor	Sus scrofa (pig)	Kb	14.0000	1	1
Vitamin D3 receptor	Homo sapiens (human)	ED50	0.1007	4	4
Vitamin D3 receptor	Rattus norvegicus (Norway rat)	ED50	500,000.0002	6	6
Xanthine dehydrogenase/oxidase	Bos taurus (cattle)	Km	32.3500	4	4

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