Roles > immunomodulator
Page last updated: 2024-08-05 15:09:24

immunomodulator

Biologically active substance whose activity affects or plays a role in the functioning of the immune system.

ChEBI ID: 50846

Members (27)

MemberDefinitionClass
5-oxo-6,8,11,14-eicosatetraenoic acidAn oxoicosatetraenoic acid having a 5-oxo group; and (6E)-, (8Z), (11Z)- and (14Z)-double bonds.5-oxo-ETE
alpha-glutamyltryptophanA dipeptide composed of L-glutamic acid and L-tryptophan joined by a peptide linkage.Glu-Trp
bigelovinA sesquiterpene lactone that is 3,3a,4,4a,7a,8,9,9a-octahydroazuleno[6,5-b]furan-2,5-dione substituted by methyl groups at positions 4a and 8, a methylidene group at position 3 and an acetoxy group at position 4. Isolated from Inula hupehensis, it exhibits antineoplastic activity.bigelovin
birb 796A member of the class of pyrazoles that is an immunomodulator used for treatment of rheumatoid arthritis, Crohn's disease and psoriasis.doramapimod
bis(3',5')-cyclic diguanylic acidA cyclic purine dinucleotide that is the 3',5'-cyclic dimer of MP.c-di-GMP
caffeic acid phenethyl esterAn alkyl caffeate ester in which 2-phenylethyl is the alkyl component.phenethyl caffeate
calcitriolA hydroxycalciol that is calcidiol in which the pro-S hydrogen of calcidiol is replaced by a hydroxy group. It is the active form of vitamin D3, produced fom calciol via hydoxylation in the liver to form calcidiol, which is subsequently oxidised in the kidney to give calcitriol.calcitriol
curcuminA beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa.curcumin
d-alpha tocopherolAn alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils.(R,R,R)-alpha-tocopherol
dimethyl fumarateAn enoate ester resulting from the formal condensation of both carboxy groups of fumaric acid with methanol. Used for treatment of adults with relapsing forms of multiple sclerosis.dimethyl fumarate
glycyrrhetinic acidA pentacyclic triterpenoid that is olean-12-ene substituted by a hydroxy group at position 3, an oxo group at position 11 and a carboxy group at position 30.glycyrrhetinic acid
hydroxyureaA member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease.hydroxyurea
iriloneA hydroxyisoflavone that is 6,7-methylenedioxyisoflavone substituted by hydroxy groups at positions 5 and 4'.irilone
lenalidomideA dicarboximide that consists of 1-oxoisoindoline bearing an amino substituent at position 4 and a 2,6-dioxopiperidin-3-yl group at position 2. Inhibits the secretion of TNF-alpha.lenalidomide
lespenefrilA glycosyloxyflavone that is kaempferol attached to alpha-L-rhamnopyranosyl residues at positions 3 and 7 respectively via glycosidic linkages. It has been isolated from the aerial parts of Vicia faba and Lotus edulis.kaempferol 3,7-di-O-alpha-L-rhamnoside
levamisoleA 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole that has S configuration. It is used (generally as the monohydrochloride salt) to treat parasitic worm infections in pigs, sheep and cattle and was formerly used in humans as an adjuvant to chemotherapy for the treatment of various cancers. It is also widely used as an adulterant to coccaine.levamisole
lisofyllineA 1-(5-hydroxyhexyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione that has (R)-configuration. A synthetic small molecule which was under development for the treatment of type 1 diabetes mellitus.(R)-lisofylline
luteolinA tetrahydroxyflavone in which the four hydroxy groups are located at positions 3', 4', 5 and 7. It is thought to play an important role in the human body as an antioxidant, a free radical scavenger, an anti-inflammatory agent and an immune system modulator as well as being active against several cancers.luteolin
miltefosineA phospholipid that is the hexadecyl monoester of phosphocholine.miltefosine
monomethyl fumarateA dicarboxylic acid monoester resulting from the formal condensation of one of the carboxy groups of fumaric acid with methanol. Is is a metabolite of dimethyl fumarate and used for the the treatment of patients with relapsing multiple sclerosis (MS). It also induces the NFE2L2 (Nrf2) transcription factor by binding to KEAP1.monomethyl fumarate
nicotineA 3-(1-methylpyrrolidin-2-yl)pyridine in which the chiral centre has S-configuration. The naturally occurring and most active enantiomer of nicotine, isolated from Nicotiana tabacum.(S)-nicotine
pomalidomideAn aromatic amine that is thalidomide substituted at position 4 on the isoindole ring system by an amino group. Used for the treatment of multiple myeloma in patients who failed to respond to previous therapies.pomalidomide
salvigeninA trimethoxyflavone that is scutellarein in which the hydroxy groups at positions 4', 6, and 7 are replaced by methoxy groups.salvigenin
solasodineAn oxaspiro compound and steroid alkaloid sapogenin with formula C27H43NO2 found in the Solanum (nightshade) family. It is used as a precursor in the synthesis of complex steroidal compounds such as contraceptive pills.solasodine
su 11248sunitinib
tepoxalinA hydroxamic acid obtained by formal condensation of the carboxy group of 3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)pyrazol-3-yl]propanoic acid with the amino group of N-methylhydroxylamine. It is used in veterinary medicine for the control of pain and inflammation caused by musculoskeletal disorders such as hip dysplasia and arthritis in dogs.tepoxalin
theophyllineA dimethylxanthine having the two methyl groups located at positions 1 and 3. It is structurally similar to caffeine and is found in green and black tea.theophylline

Research

Studies (134,577)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-199033,336 (24.77)18.7374
1990's22,102 (16.42)18.2507
2000's27,510 (20.44)29.6817
2010's37,771 (28.07)24.3611
2020's13,858 (10.30)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials11,546 (8.10%)5.53%
Reviews13,710 (9.61%)6.00%
Case Studies5,450 (3.82%)4.05%
Observational305 (0.21%)0.25%
Other111,613 (78.26%)84.16%

Protein Targets (1,120)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1Homo sapiens (human)Potency23.818515
15-lipoxygenase, partialHomo sapiens (human)Potency6.607215
67.9K proteinVaccinia virusPotency19.777525
acetylcholinesteraseHomo sapiens (human)Potency59.668945
activating transcription factor 6Homo sapiens (human)Potency21.151226
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency23.859419
alpha-galactosidaseHomo sapiens (human)Potency50.118711
Alpha-synucleinHomo sapiens (human)Potency11.511014
apical membrane antigen 1, AMA1Plasmodium falciparum 3D7Potency7.079511
AR proteinHomo sapiens (human)Potency19.67851030
aryl hydrocarbon receptorHomo sapiens (human)Potency32.038139
arylsulfatase AHomo sapiens (human)Potency24.711413
ATAD5 protein, partialHomo sapiens (human)Potency16.906145
Ataxin-2Homo sapiens (human)Potency44.153412
ATP-dependent phosphofructokinaseTrypanosoma brucei brucei TREU927Potency15.190246
ATPase family AAA domain-containing protein 5Homo sapiens (human)Potency48.369624
atrial natriuretic peptide receptor 1 precursorHomo sapiens (human)Potency3.013111
Bloom syndrome protein isoform 1Homo sapiens (human)Potency28.964438
BRCA1Homo sapiens (human)Potency35.481311
bromodomain adjacent to zinc finger domain 2BHomo sapiens (human)Potency40.585113
caspase 7, apoptosis-related cysteine proteaseHomo sapiens (human)Potency47.647912
caspase-1 isoform alpha precursorHomo sapiens (human)Potency23.735812
caspase-3Homo sapiens (human)Potency47.647912
Caspase-7Homo sapiens (human)Potency12.589311
Cellular tumor antigen p53Homo sapiens (human)Potency20.8601318
cellular tumor antigen p53 isoform aHomo sapiens (human)Potency20.077025
Chain A, 2-oxoglutarate OxygenaseHomo sapiens (human)Potency20.921217
Chain A, ATP-DEPENDENT DNA HELICASE Q1Homo sapiens (human)Potency13.121336
Chain A, Beta-lactamaseEscherichia coli K-12Potency19.952611
Chain A, Breast cancer type 1 susceptibility proteinHomo sapiens (human)Potency5.011913
Chain A, CruzipainTrypanosoma cruziPotency19.157213
Chain A, Ferritin light chainEquus caballus (horse)Potency18.754815
Chain A, HADH2 proteinHomo sapiens (human)Potency15.234226
Chain A, JmjC domain-containing histone demethylation protein 3AHomo sapiens (human)Potency71.075413
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASEHomo sapiens (human)Potency7.550516
Chain A, Putative fructose-1,6-bisphosphate aldolaseGiardia intestinalisPotency16.776114
Chain A, TYROSYL-DNA PHOSPHODIESTERASEHomo sapiens (human)Potency20.773916
Chain B, HADH2 proteinHomo sapiens (human)Potency15.234226
chromobox protein homolog 1Homo sapiens (human)Potency62.050612
cytochrome P450 2C19 precursorHomo sapiens (human)Potency15.848911
cytochrome P450 2C9 precursorHomo sapiens (human)Potency31.622811
cytochrome P450 2C9, partialHomo sapiens (human)Potency6.262812
cytochrome P450 2D6Homo sapiens (human)Potency19.702114
cytochrome P450 2D6 isoform 1Homo sapiens (human)Potency31.622811
cytochrome P450 3A4 isoform 1Homo sapiens (human)Potency20.1221212
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency17.750514
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency34.492513
D(1A) dopamine receptorHomo sapiens (human)Potency11.266522
D(1A) dopamine receptorSus scrofa (pig)Potency0.656111
DNA dC->dU-editing enzyme APOBEC-3F isoform aHomo sapiens (human)Potency14.348412
DNA dC->dU-editing enzyme APOBEC-3G isoform 1Homo sapiens (human)Potency27.245423
DNA polymerase betaHomo sapiens (human)Potency25.874012
DNA polymerase eta isoform 1Homo sapiens (human)Potency23.915412
DNA polymerase iota isoform a (long)Homo sapiens (human)Potency46.205414
DNA polymerase kappa isoform 1Homo sapiens (human)Potency20.650819
dopamine D1 receptorHomo sapiens (human)Potency8.199511
endonuclease IVEscherichia coliPotency25.118911
estrogen nuclear receptor alphaHomo sapiens (human)Potency32.0290837
estrogen receptor 2 (ER beta)Homo sapiens (human)Potency22.261624
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency18.3329824
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency12.8583112
EWS/FLI fusion proteinHomo sapiens (human)Potency18.0675415
farnesoid X nuclear receptorHomo sapiens (human)Potency31.1398512
flap endonuclease 1Homo sapiens (human)Potency30.350215
Fumarate hydrataseHomo sapiens (human)Potency20.214813
GVesicular stomatitis virusPotency6.262812
GABA theta subunitRattus norvegicus (Norway rat)Potency20.122116
galactokinaseHomo sapiens (human)Potency47.269011
GALC proteinHomo sapiens (human)Potency0.707911
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)Potency20.122116
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)Potency20.122116
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)Potency20.122116
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)Potency20.122116
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)Potency20.122116
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)Potency20.122116
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)Potency20.122116
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)Potency20.122116
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)Potency20.122116
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)Potency20.122116
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)Potency20.122116
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)Potency20.122116
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)Potency20.122116
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)Potency20.122116
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)Potency20.122116
gemininHomo sapiens (human)Potency11.1194415
GLI family zinc finger 3Homo sapiens (human)Potency24.3984310
glp-1 receptor, partialHomo sapiens (human)Potency11.220211
GLS proteinHomo sapiens (human)Potency19.168827
glucocerebrosidaseHomo sapiens (human)Potency26.425714
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency32.6712410
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency52.015912
GTP-binding nuclear protein Ran isoform 1Homo sapiens (human)Potency29.019413
Guanine nucleotide-binding protein GHomo sapiens (human)Potency23.350712
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)Homo sapiens (human)Potency11.635928
heat shock protein beta-1Homo sapiens (human)Potency30.530727
hemoglobin subunit betaHomo sapiens (human)Potency39.810711
Histamine H2 receptorCavia porcellus (domestic guinea pig)Potency15.2569213
histone acetyltransferase KAT2A isoform 1Homo sapiens (human)Potency39.810711
Histone H2A.xCricetulus griseus (Chinese hamster)Potency70.433026
histone-lysine N-methyltransferase 2A isoform 2 precursorHomo sapiens (human)Potency42.460012
HLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)Potency6.262812
huntingtin isoform 2Homo sapiens (human)Potency19.514712
hypoxia-inducible factor 1 alpha subunitHomo sapiens (human)Potency35.162726
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)Homo sapiens (human)Potency3.290026
IDH1Homo sapiens (human)Potency18.437613
importin subunit beta-1 isoform 1Homo sapiens (human)Potency30.509426
Inositol hexakisphosphate kinase 1Homo sapiens (human)Potency6.262814
Inositol monophosphatase 1Rattus norvegicus (Norway rat)Potency21.437013
Integrin alpha-IIbHomo sapiens (human)Potency19.137313
Integrin beta-3Homo sapiens (human)Potency19.137313
Interferon betaHomo sapiens (human)Potency20.2605211
interleukin 8Homo sapiens (human)Potency65.717312
lamin isoform A-delta10Homo sapiens (human)Potency7.5911211
lethal factor (plasmid)Bacillus anthracis str. A2012Potency6.748214
LuciferasePhotinus pyralis (common eastern firefly)Potency29.499637
lysosomal alpha-glucosidase preproproteinHomo sapiens (human)Potency32.312812
M-phase phosphoprotein 8Homo sapiens (human)Potency38.748212
Microtubule-associated protein tauHomo sapiens (human)Potency14.3560214
mitogen-activated protein kinase 1Homo sapiens (human)Potency32.184123
muscleblind-like protein 1 isoform 1Homo sapiens (human)Potency28.796812
neuropeptide S receptor isoform AHomo sapiens (human)Potency0.316211
NFKB1 protein, partialHomo sapiens (human)Potency3.162322
nonstructural protein 1Influenza A virus (A/WSN/1933(H1N1))Potency5.011911
Nrf2Homo sapiens (human)Potency15.611723
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency33.122349
nuclear factor erythroid 2-related factor 2 isoform 2Homo sapiens (human)Potency20.596211
nuclear factor NF-kappa-B p105 subunit isoform 1Homo sapiens (human)Potency50.118711
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_aHomo sapiens (human)Potency14.718413
Nuclear receptor ROR-gammaHomo sapiens (human)Potency36.382113
nuclear receptor ROR-gamma isoform 1Mus musculus (house mouse)Potency21.3177220
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency32.4248311
P53Homo sapiens (human)Potency21.154612
ParkinHomo sapiens (human)Potency25.740022
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1Homo sapiens (human)Potency57.391113
peripheral myelin protein 22Rattus norvegicus (Norway rat)Potency7.718515
peripheral myelin protein 22 isoform 1Homo sapiens (human)Potency42.843912
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency23.4296516
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency23.415459
phosphoglycerate kinaseTrypanosoma brucei brucei TREU927Potency28.183811
phosphopantetheinyl transferaseBacillus subtilisPotency58.982817
PINK1Homo sapiens (human)Potency22.387211
plasminogen precursorMus musculus (house mouse)Potency5.432014
polyproteinZika virusPotency20.214813
polyunsaturated fatty acid lipoxygenase ALOX12Homo sapiens (human)Potency16.624314
Polyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)Potency10.347115
potassium voltage-gated channel subfamily H member 2 isoform dHomo sapiens (human)Potency3.814612
PPM1D proteinHomo sapiens (human)Potency23.371016
pregnane X nuclear receptorHomo sapiens (human)Potency47.183226
pregnane X receptorRattus norvegicus (Norway rat)Potency79.432811
progesterone receptorHomo sapiens (human)Potency37.572325
pyruvate kinase PKM isoform aHomo sapiens (human)Potency28.183822
Rap guanine nucleotide exchange factor 3Homo sapiens (human)Potency24.840122
RAR-related orphan receptor gammaMus musculus (house mouse)Potency26.524426
regulator of G-protein signaling 4Homo sapiens (human)Potency0.984214
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency21.2647315
retinoid X nuclear receptor alphaHomo sapiens (human)Potency20.0740414
serine/threonine-protein kinase mTOR isoform 1Homo sapiens (human)Potency4.404333
serine/threonine-protein kinase PLK1Homo sapiens (human)Potency37.685811
SMAD family member 2Homo sapiens (human)Potency32.987725
SMAD family member 3Homo sapiens (human)Potency32.987725
Smad3Homo sapiens (human)Potency15.082715
snurportin-1Homo sapiens (human)Potency30.509426
Spike glycoproteinSevere acute respiratory syndrome-related coronavirusPotency26.968012
survival motor neuron protein isoform dHomo sapiens (human)Potency14.598314
TAR DNA-binding protein 43Homo sapiens (human)Potency25.590314
TDP1 proteinHomo sapiens (human)Potency14.1810226
thioredoxin glutathione reductaseSchistosoma mansoniPotency39.810712
thioredoxin reductaseRattus norvegicus (Norway rat)Potency19.853038
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency26.9915318
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency50.265744
thyroid stimulating hormone receptorHomo sapiens (human)Potency25.369459
thyrotropin-releasing hormone receptorHomo sapiens (human)Potency31.005812
transcriptional regulator ERG isoform 3Homo sapiens (human)Potency11.464212
tumor susceptibility gene 101 proteinHomo sapiens (human)Potency19.952611
tyrosine-protein kinase YesHomo sapiens (human)Potency10.908212
urokinase plasminogen activator surface receptor precursorMus musculus (house mouse)Potency5.432014
urokinase-type plasminogen activator precursorMus musculus (house mouse)Potency5.432014
USP1 protein, partialHomo sapiens (human)Potency34.6753210
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency21.743028
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency30.570659
vitamin D3 receptor isoform VDRAHomo sapiens (human)Potency50.451212
Voltage-dependent calcium channel gamma-2 subunitMus musculus (house mouse)Potency52.015912
WRNHomo sapiens (human)Potency6.520122

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrialHomo sapiens (human)IC5030.000011
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform aHomo sapiens (human)IC509.699522
1-deoxy-D-xylulose 5-phosphate reductoisomeraseEscherichia coli K-12IC503.400011
10 kDa chaperonin Escherichia coliIC503.000022
10 kDa heat shock protein, mitochondrialHomo sapiens (human)IC508.300011
17-beta-hydroxysteroid dehydrogenase type 2Homo sapiens (human)IC501.730011
3-oxoacyl-acyl-carrier protein reductase Plasmodium falciparum (malaria parasite P. falciparum)IC504.000011
3-oxoacyl-acyl-carrier protein reductase Plasmodium falciparum (malaria parasite P. falciparum)Ki1.300022
5-hydroxytryptamine receptor 1AHomo sapiens (human)Ki86.000011
5-hydroxytryptamine receptor 3AHomo sapiens (human)Ki71.000012
5-hydroxytryptamine receptor 3BHomo sapiens (human)Ki71.000012
5-hydroxytryptamine receptor 3CHomo sapiens (human)Ki71.000012
5-hydroxytryptamine receptor 3DHomo sapiens (human)Ki71.000012
5-hydroxytryptamine receptor 3EHomo sapiens (human)Ki71.000012
5'-AMP-activated protein kinase catalytic subunit alpha-1Homo sapiens (human)IC500.158011
5'-AMP-activated protein kinase catalytic subunit alpha-2Homo sapiens (human)IC500.061711
5'-nucleotidaseRattus norvegicus (Norway rat)IC5020.200011
60 kDa chaperoninEscherichia coli K-12IC50250.000011
60 kDa chaperonin Escherichia coliIC503.000022
60 kDa heat shock protein, mitochondrialHomo sapiens (human)IC508.300011
72 kDa type IV collagenaseHomo sapiens (human)IC503.610011
Acetylcholine receptor subunit alphaHomo sapiens (human)IC5011.000022
Acetylcholine receptor subunit alphaTetronarce californica (Pacific electric ray)IC500.002522
Acetylcholine receptor subunit alphaHomo sapiens (human)Ki3.313944
Acetylcholine receptor subunit alphaTetronarce californica (Pacific electric ray)Ki8.135022
Acetylcholine receptor subunit betaHomo sapiens (human)IC501.000011
Acetylcholine receptor subunit betaTetronarce californica (Pacific electric ray)IC500.002522
Acetylcholine receptor subunit betaHomo sapiens (human)Ki3.313944
Acetylcholine receptor subunit betaTetronarce californica (Pacific electric ray)Ki8.135022
Acetylcholine receptor subunit beta-like 2Drosophila melanogaster (fruit fly)IC504.000011
Acetylcholine receptor subunit beta-like 2Drosophila melanogaster (fruit fly)Ki2.700011
Acetylcholine receptor subunit deltaHomo sapiens (human)IC501.000011
Acetylcholine receptor subunit deltaTetronarce californica (Pacific electric ray)IC500.002522
Acetylcholine receptor subunit deltaHomo sapiens (human)Ki3.313944
Acetylcholine receptor subunit deltaTetronarce californica (Pacific electric ray)Ki8.135022
Acetylcholine receptor subunit gammaHomo sapiens (human)IC501.000011
Acetylcholine receptor subunit gammaTetronarce californica (Pacific electric ray)IC500.002522
Acetylcholine receptor subunit gammaHomo sapiens (human)Ki3.313944
Acetylcholine receptor subunit gammaTetronarce californica (Pacific electric ray)Ki8.135022
Acetylcholine-binding proteinLymnaea stagnalis (great pond snail)Ki0.223678
AcetylcholinesteraseElectrophorus electricus (electric eel)IC50132.130022
AcetylcholinesteraseHomo sapiens (human)IC505.435022
AcetylcholinesteraseElectrophorus electricus (electric eel)Ki100.000011
AcetylcholinesteraseHomo sapiens (human)Ki65.800011
Activin receptor type-1BHomo sapiens (human)IC5044.000011
Adenosine receptor A1Bos taurus (cattle)IC501,006,650,005.043333
Adenosine receptor A1Homo sapiens (human)IC5017.104011
Adenosine receptor A1Rattus norvegicus (Norway rat)IC5019.000022
Adenosine receptor A1Bos taurus (cattle)Ki4.114377
Adenosine receptor A1Cavia porcellus (domestic guinea pig)Ki21.333366
Adenosine receptor A1Gallus gallus (chicken)Ki6.000011
Adenosine receptor A1Homo sapiens (human)Ki6.63991818
Adenosine receptor A1Rattus norvegicus (Norway rat)Ki9.27813137
Adenosine receptor A2aHomo sapiens (human)IC5012.007011
Adenosine receptor A2aCavia porcellus (domestic guinea pig)Ki14.000022
Adenosine receptor A2aHomo sapiens (human)Ki8.54862727
Adenosine receptor A2aRattus norvegicus (Norway rat)Ki15.96522431
Adenosine receptor A2bHomo sapiens (human)Ki10.14261919
Adenosine receptor A2bRattus norvegicus (Norway rat)Ki15.38961824
Adenosine receptor A3Homo sapiens (human)Ki54.86572020
Adenosine receptor A3Rattus norvegicus (Norway rat)Ki45.405689
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1Homo sapiens (human)IC508.200011
Aldo-keto reductase family 1 member A1Homo sapiens (human)IC5050.000011
Aldo-keto reductase family 1 member B1Bos taurus (cattle)IC505.162022
Aldo-keto reductase family 1 member B1Homo sapiens (human)IC5057.586055
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)IC502.663522
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)Ki3.756011
Aldo-keto reductase family 1 member B10Homo sapiens (human)IC5020.408366
Aldo-keto reductase family 1 member B10Homo sapiens (human)Ki0.046011
Aldo-keto reductase family 1 member C1Homo sapiens (human)IC5021.120022
Aldo-keto reductase family 1 member C2 Homo sapiens (human)IC5015.880022
Aldo-keto reductase family 1 member C3Homo sapiens (human)IC502.705022
Aldo-keto reductase family 1 member C4Homo sapiens (human)IC505.275022
ALK tyrosine kinase receptorHomo sapiens (human)IC5010.784933
alkaline phosphatase, germ cell type preproproteinHomo sapiens (human)IC50100.000011
alkaline phosphatase, intestinalHomo sapiens (human)IC50100.000011
Alkaline phosphatase, placental typeHomo sapiens (human)IC50400.000044
Alkaline phosphatase, tissue-nonspecific isozymeHomo sapiens (human)IC5028.268346
Alkaline phosphatase, tissue-nonspecific isozymeHomo sapiens (human)Ki49.000012
Alkaline phosphatase, tissue-nonspecific isozyme Bos taurus (cattle)IC5019.406055
Alkaline phosphatase, tissue-nonspecific isozyme Bos taurus (cattle)Ki1.810011
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproproteinHomo sapiens (human)IC50100.000011
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)IC505.400011
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)IC505.400011
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)IC505.400011
Alpha-amylase 1A Homo sapiens (human)IC5018.400022
Alpha-synucleinHomo sapiens (human)IC5063.340033
Amine oxidase [flavin-containing] AHomo sapiens (human)IC503.850044
Amine oxidase [flavin-containing] AHomo sapiens (human)Ki0.710011
Amine oxidase [flavin-containing] BHomo sapiens (human)IC5016.855044
Amine oxidase [flavin-containing] BHomo sapiens (human)Ki21.500011
Aminopeptidase NHomo sapiens (human)IC5015.500011
Aminopeptidase NSus scrofa (pig)IC5015.500011
Amyloid-beta precursor proteinHomo sapiens (human)IC509.74263131
Androgen receptorHomo sapiens (human)IC5010.000011
Angiopoietin-1 receptorHomo sapiens (human)IC502.760844
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)IC50290.000022
AP2-associated protein kinase 1Homo sapiens (human)IC500.046222
AromataseHomo sapiens (human)IC500.018011
ATP-binding cassette sub-family C member 3Homo sapiens (human)IC50133.000015
ATP-dependent translocase ABCB1Homo sapiens (human)IC5019.600011
Aurora kinase AHomo sapiens (human)IC5015.918522
Aurora kinase BHomo sapiens (human)IC5035.126733
BDNF/NT-3 growth factors receptorHomo sapiens (human)IC500.525022
Beta lactamase (plasmid)Pseudomonas aeruginosaIC507.751011
Beta-adrenergic receptor kinase 1Bos taurus (cattle)IC50130.000011
Beta-glucuronidaseEscherichia coli K-12IC5012.150011
Beta-glucuronidaseRattus norvegicus (Norway rat)IC5097.210011
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)Plasmodium falciparum (malaria parasite P. falciparum)IC505.000011
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)Plasmodium falciparum (malaria parasite P. falciparum)Ki11.500011
Beta-secretase 1Homo sapiens (human)IC50343.000011
Bifunctional epoxide hydrolase 2Homo sapiens (human)IC5010.000011
Bile salt export pumpHomo sapiens (human)IC50288.7510310
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)IC504.510033
Bromodomain-containing protein 4Homo sapiens (human)IC505.190011
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1AHomo sapiens (human)IC50320.000011
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Bos taurus (cattle)IC50340.400055
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BBos taurus (cattle)IC50300.500044
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BHomo sapiens (human)IC50320.000011
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CHomo sapiens (human)IC50320.000011
Calcium/calmodulin-dependent protein kinase type II subunit betaHomo sapiens (human)IC5040.000011
Calcium/calmodulin-dependent protein kinase type II subunit deltaHomo sapiens (human)IC5030.000011
cAMP-dependent protein kinase catalytic subunit alphaHomo sapiens (human)IC5020.000011
cAMP-dependent protein kinase catalytic subunit betaHomo sapiens (human)IC5020.000011
cAMP-dependent protein kinase catalytic subunit gammaHomo sapiens (human)IC5020.000011
cAMP-dependent protein kinase catalytic subunit PRKXHomo sapiens (human)IC5030.000011
cAMP-specific 3',5'-cyclic phosphodiesterase 4AHomo sapiens (human)IC50574.250044
cAMP-specific 3',5'-cyclic phosphodiesterase 4AHomo sapiens (human)Ki530.000011
cAMP-specific 3',5'-cyclic phosphodiesterase 4ARattus norvegicus (Norway rat)Ki530.000011
cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)IC50527.750044
cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)Ki530.000011
cAMP-specific 3',5'-cyclic phosphodiesterase 4BRattus norvegicus (Norway rat)Ki530.000011
cAMP-specific 3',5'-cyclic phosphodiesterase 4CHomo sapiens (human)IC50637.000033
cAMP-specific 3',5'-cyclic phosphodiesterase 4CHomo sapiens (human)Ki530.000011
cAMP-specific 3',5'-cyclic phosphodiesterase 4CRattus norvegicus (Norway rat)Ki530.000011
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)IC50637.000033
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)Ki530.000011
cAMP-specific 3',5'-cyclic phosphodiesterase 4D Rattus norvegicus (Norway rat)Ki530.000011
Canalicular multispecific organic anion transporter 1Homo sapiens (human)IC50133.000015
Carbonic anhydrase 1Homo sapiens (human)Ki4.548025
Carbonic anhydrase 12Homo sapiens (human)Ki0.060311
Carbonic anhydrase 2Homo sapiens (human)Ki7.405336
Carbonic anhydrase 3Bos taurus (cattle)Ki3.185014
Carbonic anhydrase 4Homo sapiens (human)Ki21.005536
Carbonic anhydrase 5A, mitochondrialHomo sapiens (human)Ki31.000011
Carbonic anhydrase 7Homo sapiens (human)Ki0.004711
Carbonic anhydrase 9Homo sapiens (human)Ki23.000011
Casein kinase I isoform alphaHomo sapiens (human)IC5015.000522
Casein kinase II subunit alphaHomo sapiens (human)IC5010.500033
Casein kinase II subunit alpha 3Homo sapiens (human)IC500.500011
Casein kinase II subunit alpha'Homo sapiens (human)IC500.833333
Casein kinase II subunit betaHomo sapiens (human)IC500.833333
Cationic trypsinBos taurus (cattle)IC5035.300011
CDGSH iron-sulfur domain-containing protein 1Homo sapiens (human)IC502.360011
CDGSH iron-sulfur domain-containing protein 1Homo sapiens (human)Ki0.101011
Cereblon isoform 4Magnetospirillum gryphiswaldenseKi1.950012
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)IC50210.000011
cGMP-dependent protein kinase 1 Homo sapiens (human)IC5030.000022
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)IC50300.000022
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)IC50300.000022
Chain A, Casein Kinase Ii Subunit AlphaZea maysIC500.350013
Chain A, Pyridoxal KinaseHomo sapiens (human)Ki50.000012
Chemotaxis protein CheAEscherichia coli K-12IC50111.000011
Chitotriosidase-1Homo sapiens (human)IC501,000.000012
CholinesteraseEquus caballus (horse)IC50300.000011
CholinesteraseHomo sapiens (human)IC505.000011
CholinesteraseEquus caballus (horse)Ki100.000011
Collagenase 3Homo sapiens (human)IC5010.050011
Corticosteroid 11-beta-dehydrogenase isozyme 1Homo sapiens (human)IC500.185399
Corticosteroid 11-beta-dehydrogenase isozyme 1Mus musculus (house mouse)IC500.012466
Corticosteroid 11-beta-dehydrogenase isozyme 1 Rattus norvegicus (Norway rat)IC500.090011
Corticosteroid 11-beta-dehydrogenase isozyme 2Homo sapiens (human)IC500.103555
Corticosteroid 11-beta-dehydrogenase isozyme 2Rattus norvegicus (Norway rat)IC500.360022
CREB-binding proteinHomo sapiens (human)IC5025.000044
CruzipainTrypanosoma cruziIC5091.500022
Cyclin homologHerpesvirus saimiri (strain 11)IC5077.700014
Cyclin-A1Homo sapiens (human)IC5030.000011
Cyclin-A2Homo sapiens (human)IC5030.000011
Cyclin-dependent kinase 1Homo sapiens (human)IC50345.400033
Cyclin-dependent kinase 1Oryzias latipes (Japanese medaka)IC5077.700014
Cyclin-dependent kinase 2Homo sapiens (human)IC5052.500044
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)IC5053.514347
Cyclin-dependent kinase 6Homo sapiens (human)IC50122.160025
Cyclin-dependent kinase 8Homo sapiens (human)IC501.000011
Cyclin-dependent kinase 9Homo sapiens (human)IC5030.000011
Cyclin-dependent-like kinase 5 Homo sapiens (human)IC5046.950058
Cyclin-T1Homo sapiens (human)IC5030.000011
Cysteine protease Trypanosoma brucei rhodesienseIC507.750011
Cytochrome P450 1A1Homo sapiens (human)IC501.249011
Cytochrome P450 1A1Homo sapiens (human)Ki1.896723
Cytochrome P450 1A2Homo sapiens (human)IC501,401.123333
Cytochrome P450 1B1Homo sapiens (human)IC500.219522
Cytochrome P450 1B1Homo sapiens (human)Ki1.228022
Cytochrome P450 2A13Homo sapiens (human)Ki72.000011
Cytochrome P450 2A5Mus musculus (house mouse)IC50159.956011
Cytochrome P450 2A6Homo sapiens (human)IC50210.676323
Cytochrome P450 2A6Homo sapiens (human)Ki46.266733
Cytochrome P450 2C19Homo sapiens (human)IC50100.000011
Cytochrome P450 2C19Homo sapiens (human)Ki0.000111
Cytochrome P450 2C9 Homo sapiens (human)IC5050.004622
Cytochrome P450 2D6Homo sapiens (human)IC50100.000011
Cytochrome P450 2D6Homo sapiens (human)Ki0.000111
Cytochrome P450 3A4Homo sapiens (human)IC5042.103133
Cytochrome P450 3A4Homo sapiens (human)Ki0.000111
Cytoplasmic tyrosine-protein kinase BMXHomo sapiens (human)IC5030.000011
Cytosol aminopeptidaseSus scrofa (pig)IC5049.600011
D-amino-acid oxidaseSus scrofa (pig)IC501.070022
D(3) dopamine receptorRattus norvegicus (Norway rat)Ki0.000611
Death-associated protein kinase 1Homo sapiens (human)IC5025.500022
Death-associated protein kinase 3Homo sapiens (human)IC5030.000011
Delta-type opioid receptorHomo sapiens (human)Ki26.000011
Delta-type opioid receptorMus musculus (house mouse)Ki0.440011
Delta-type opioid receptorRattus norvegicus (Norway rat)Ki0.110011
Dipeptidyl peptidase 3Homo sapiens (human)IC5022.000011
Dipeptidyl peptidase 4Homo sapiens (human)IC500.120011
Discoidin domain-containing receptor 2Homo sapiens (human)IC500.270844
DNA damage-binding protein 1Homo sapiens (human)IC501.797235
DNA topoisomerase 1Rattus norvegicus (Norway rat)IC502.830022
DNA-dependent protein kinase catalytic subunitHomo sapiens (human)IC5050.000011
Endochitinase B1Aspergillus fumigatusIC501,000.000012
Enoyl-[acyl-carrier-protein] reductase [NADH] FabIEscherichia coli K-12Ki7.050011
Enoyl-acyl-carrier protein reductase Plasmodium falciparum (malaria parasite P. falciparum)IC502.000022
Enoyl-acyl-carrier protein reductase Plasmodium falciparum (malaria parasite P. falciparum)Ki2.100011
Ephrin type-A receptor 1Homo sapiens (human)IC500.630011
Ephrin type-A receptor 2Homo sapiens (human)IC500.160011
Ephrin type-A receptor 3Homo sapiens (human)IC501.100022
Ephrin type-A receptor 4Homo sapiens (human)IC500.070011
Ephrin type-A receptor 5Homo sapiens (human)IC500.090011
Ephrin type-A receptor 7Homo sapiens (human)IC501.000011
Ephrin type-A receptor 8Homo sapiens (human)IC501.000011
Ephrin type-B receptor 1Homo sapiens (human)IC500.110011
Ephrin type-B receptor 2Homo sapiens (human)IC500.580022
Ephrin type-B receptor 3Homo sapiens (human)IC509.400011
Ephrin type-B receptor 4Homo sapiens (human)IC5025.450022
Epidermal growth factor receptorHomo sapiens (human)IC5055.96231820
Epithelial discoidin domain-containing receptor 1Homo sapiens (human)IC501.000011
Estrogen receptorHomo sapiens (human)IC507.912011
Estrogen receptorHomo sapiens (human)Ki2.260011
Fatty acid synthaseGallus gallus (chicken)IC5062.500011
Fatty acid synthaseHomo sapiens (human)IC5062.500011
Fibroblast growth factor receptor 1Homo sapiens (human)IC506.016357
Fibroblast growth factor receptor 2Homo sapiens (human)IC5024.000011
Fibroblast growth factor receptor 3Homo sapiens (human)IC5030.000011
Fibroblast growth factor receptor 4Homo sapiens (human)IC507.000011
Focal adhesion kinase 1Homo sapiens (human)IC501.800022
G protein-coupled receptor kinase 5Homo sapiens (human)IC5015.415022
G protein-coupled receptor kinase 6Homo sapiens (human)IC5030.000011
G-protein coupled receptor 35Homo sapiens (human)IC5018.600011
G1/S-specific cyclin-E1Homo sapiens (human)IC5030.000011
G2/mitotic-specific cyclin-BMarthasterias glacialis (spiny starfish)IC5077.700014
G2/mitotic-specific cyclin-B1Homo sapiens (human)IC5018.100022
G2/mitotic-specific cyclin-B2Homo sapiens (human)IC506.200011
G2/mitotic-specific cyclin-B3Homo sapiens (human)IC506.200011
Gamma-aminobutyric acid receptor subunit alpha-1Homo sapiens (human)Ki113.000012
Gamma-aminobutyric acid receptor subunit alpha-2Homo sapiens (human)Ki113.000012
Gamma-aminobutyric acid receptor subunit alpha-3Homo sapiens (human)Ki113.000012
Gamma-aminobutyric acid receptor subunit alpha-4Homo sapiens (human)Ki113.000012
Gamma-aminobutyric acid receptor subunit alpha-5Homo sapiens (human)Ki113.000012
Gamma-aminobutyric acid receptor subunit alpha-6Homo sapiens (human)Ki113.000012
Gamma-aminobutyric acid receptor subunit beta-1Homo sapiens (human)Ki113.000012
Gamma-aminobutyric acid receptor subunit beta-2Homo sapiens (human)Ki113.000012
Gamma-aminobutyric acid receptor subunit beta-3Homo sapiens (human)Ki113.000012
Gamma-aminobutyric acid receptor subunit deltaHomo sapiens (human)Ki113.000012
Gamma-aminobutyric acid receptor subunit epsilonHomo sapiens (human)Ki113.000012
Gamma-aminobutyric acid receptor subunit gamma-1Homo sapiens (human)Ki113.000012
Gamma-aminobutyric acid receptor subunit gamma-2Homo sapiens (human)Ki113.000012
Gamma-aminobutyric acid receptor subunit gamma-3Homo sapiens (human)Ki113.000012
Gamma-aminobutyric acid receptor subunit piHomo sapiens (human)Ki113.000012
Gamma-aminobutyric acid receptor subunit thetaHomo sapiens (human)Ki113.000012
Genome polyprotein Zika virusIC5053.000011
Glutathione S-transferase PHomo sapiens (human)IC5034.750022
Glycogen phosphorylase, muscle formOryctolagus cuniculus (rabbit)IC5066.000011
Glycogen synthase kinase-3 alphaHomo sapiens (human)IC500.800011
Glycogen synthase kinase-3 betaHomo sapiens (human)IC5020.635056
Glycogen synthase kinase-3 betaRattus norvegicus (Norway rat)IC5062.173225
Heat shock protein beta-1Homo sapiens (human)IC500.058011
Heme oxygenase 1 Rattus norvegicus (Norway rat)IC5010.000011
Heme oxygenase 2Rattus norvegicus (Norway rat)IC5010.000011
Hepatocyte growth factor receptorHomo sapiens (human)IC5010.285877
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7AHomo sapiens (human)IC50200.000011
High affinity nerve growth factor receptorHomo sapiens (human)IC500.580022
histidine kinase Streptococcus pneumoniae TIGR4IC50216.000011
Histone acetyltransferase p300Homo sapiens (human)IC5021.916766
Histone deacetylase 1Homo sapiens (human)IC50187.000011
Histone deacetylase 1Homo sapiens (human)Ki50.790011
Histone deacetylase 11 Homo sapiens (human)IC50187.000011
Histone deacetylase 2Homo sapiens (human)IC50187.000011
Histone deacetylase 2Homo sapiens (human)Ki97.670011
Histone deacetylase 3Homo sapiens (human)IC50187.000011
Histone deacetylase 4Homo sapiens (human)IC50187.000011
Histone deacetylase 5Homo sapiens (human)IC50187.000011
Histone deacetylase 6Homo sapiens (human)IC50187.000011
Histone deacetylase 7Homo sapiens (human)IC50187.000011
Histone deacetylase 8Homo sapiens (human)IC50187.000011
Histone deacetylase 8Homo sapiens (human)Ki64.980011
Histone deacetylase 9Homo sapiens (human)IC50187.000011
Histone-lysine N-methyltransferase SETD7Homo sapiens (human)IC506.080011
Homeobox protein Nkx-2.5 Mus musculus (house mouse)IC5022.000011
Homeodomain-interacting protein kinase 1Homo sapiens (human)IC5030.000011
Homeodomain-interacting protein kinase 3Homo sapiens (human)IC5030.000011
Hydroxycarboxylic acid receptor 2Homo sapiens (human)Ki0.180011
hypothetical protein SA1422Staphylococcus aureus subsp. aureus N315IC5042.900022
Inhibitor of nuclear factor kappa-B kinase subunit betaHomo sapiens (human)IC5025.000022
Inositol hexakisphosphate kinase 2Homo sapiens (human)IC501.300011
Inositol polyphosphate multikinaseHomo sapiens (human)IC505.500011
Insulin receptorHomo sapiens (human)IC5016.600022
Insulin receptor-related proteinHomo sapiens (human)IC5030.000011
Insulin-like growth factor 1 receptorHomo sapiens (human)IC5030.000011
Integrase Human immunodeficiency virus 1IC5025.33291010
integrase, partialHuman immunodeficiency virus 1IC507.894522
Interleukin-1 receptor-associated kinase 1Homo sapiens (human)IC5030.000011
Interleukin-1 receptor-associated kinase 4Homo sapiens (human)IC5030.000011
Interstitial collagenaseHomo sapiens (human)IC503.030011
intestinal alkaline phosphatase precursorMus musculus (house mouse)IC5018.700011
Intestinal-type alkaline phosphataseBos taurus (cattle)IC50171.722055
Intestinal-type alkaline phosphataseHomo sapiens (human)IC50171.701756
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)IC500.660011
Lactoylglutathione lyaseHomo sapiens (human)IC507.700011
Lactoylglutathione lyaseHomo sapiens (human)Ki0.005011
Lactoylglutathione lyaseMus musculus (house mouse)Ki0.290011
large T antigenBetapolyomavirus macacaeIC5011.900011
lens epithelium-derived growth factor p75Homo sapiens (human)IC507.894522
Leucine-rich repeat serine/threonine-protein kinase 2Homo sapiens (human)IC500.021522
Liver carboxylesterase B-1Rattus norvegicus (Norway rat)IC500.045011
Lysine-specific histone demethylase 1AHomo sapiens (human)IC509.600011
M-phase inducer phosphatase 1Homo sapiens (human)IC5025.000011
M1-family alanyl aminopeptidasePlasmodium falciparum 3D7IC5022.860011
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)IC506.071055
Macrophage metalloelastaseHomo sapiens (human)IC500.980011
Macrophage-stimulating protein receptorHomo sapiens (human)IC5030.000011
MAP kinase-activated protein kinase 2Homo sapiens (human)IC5030.000011
MAP kinase-activated protein kinase 3Homo sapiens (human)IC5030.000011
MAP kinase-activated protein kinase 5Homo sapiens (human)IC5030.000011
MAP kinase-interacting serine/threonine-protein kinase 1Homo sapiens (human)IC500.179011
MAP kinase-interacting serine/threonine-protein kinase 2Homo sapiens (human)IC500.579011
Mast/stem cell growth factor receptor KitHomo sapiens (human)GI500.19865353
Mast/stem cell growth factor receptor KitMus musculus (house mouse)GI500.003011
Mast/stem cell growth factor receptor KitHomo sapiens (human)IC501.78752020
Mast/stem cell growth factor receptor KitHomo sapiens (human)Ki0.004011
Matrix metalloproteinase-9Homo sapiens (human)IC505.620011
Microtubule-associated protein tauHomo sapiens (human)IC5054.875044
Misshapen-like kinase 1Homo sapiens (human)IC500.040011
Mitogen-activated protein kinase 1Homo sapiens (human)IC504.943022
Mitogen-activated protein kinase 10Homo sapiens (human)IC506.540045
Mitogen-activated protein kinase 11Homo sapiens (human)IC502.204855
Mitogen-activated protein kinase 12Homo sapiens (human)IC500.229855
Mitogen-activated protein kinase 13Homo sapiens (human)IC500.105733
Mitogen-activated protein kinase 14Homo sapiens (human)IC501.07561920
Mitogen-activated protein kinase 14Homo sapiens (human)Ki0.018644
Mitogen-activated protein kinase 3 Homo sapiens (human)IC5025.000022
Mitogen-activated protein kinase 8Homo sapiens (human)IC5013.666733
Mitogen-activated protein kinase 9Homo sapiens (human)IC500.298988
Mitogen-activated protein kinase kinase kinase 20Homo sapiens (human)IC501.000011
Mitogen-activated protein kinase kinase kinase 5Homo sapiens (human)IC5030.000011
Mitogen-activated protein kinase kinase kinase 7Homo sapiens (human)IC500.900011
Mitogen-activated protein kinase kinase kinase 9Homo sapiens (human)IC5030.000011
Mitogen-activated protein kinase kinase kinase kinase 4Homo sapiens (human)IC501.000011
Mu-type opioid receptorCavia porcellus (domestic guinea pig)IC500.018011
Mu-type opioid receptorCavia porcellus (domestic guinea pig)Ki0.226022
Mu-type opioid receptorRattus norvegicus (Norway rat)Ki0.440011
Multidrug resistance-associated protein 4Homo sapiens (human)IC50133.000015
Muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)IC50360.000012
Muscarinic acetylcholine receptor M2Rattus norvegicus (Norway rat)IC50360.000011
Muscarinic acetylcholine receptor M3Rattus norvegicus (Norway rat)IC50360.000011
Muscarinic acetylcholine receptor M4Rattus norvegicus (Norway rat)IC50360.000011
Muscarinic acetylcholine receptor M4Mus musculus (house mouse)Ki2.110011
Muscarinic acetylcholine receptor M4Rattus norvegicus (Norway rat)Ki1.059722
Muscarinic acetylcholine receptor M5Rattus norvegicus (Norway rat)IC50360.000011
NACHT, LRR and PYD domains-containing protein 3 Homo sapiens (human)IC5024.200011
NAD-dependent protein deacetylase sirtuin-2Homo sapiens (human)IC50122.700011
NADPH oxidase 4Homo sapiens (human)IC500.850011
Neuraminidase Influenza A virus (A/Wilson-Smith/1933(H1N1))IC5032.650044
Neuraminidase Influenza A virus (A/Wilson-Smith/1933(H1N1))Ki19.600011
Neuronal acetylcholine receptor subunit alpha-10Rattus norvegicus (Norway rat)IC500.005022
Neuronal acetylcholine receptor subunit alpha-10Rattus norvegicus (Norway rat)Ki0.007034
Neuronal acetylcholine receptor subunit alpha-2Mus musculus (house mouse)IC500.004011
Neuronal acetylcholine receptor subunit alpha-2Rattus norvegicus (Norway rat)IC500.005022
Neuronal acetylcholine receptor subunit alpha-2Homo sapiens (human)Ki0.059533
Neuronal acetylcholine receptor subunit alpha-2Mus musculus (house mouse)Ki0.001211
Neuronal acetylcholine receptor subunit alpha-2Rattus norvegicus (Norway rat)Ki0.04382728
Neuronal acetylcholine receptor subunit alpha-3Homo sapiens (human)IC500.389944
Neuronal acetylcholine receptor subunit alpha-3Mus musculus (house mouse)IC500.004011
Neuronal acetylcholine receptor subunit alpha-3Rattus norvegicus (Norway rat)IC505.002544
Neuronal acetylcholine receptor subunit alpha-3Homo sapiens (human)Ki0.37632020
Neuronal acetylcholine receptor subunit alpha-3Mus musculus (house mouse)Ki0.084122
Neuronal acetylcholine receptor subunit alpha-3Rattus norvegicus (Norway rat)Ki0.21783742
Neuronal acetylcholine receptor subunit alpha-4Homo sapiens (human)IC500.34561012
Neuronal acetylcholine receptor subunit alpha-4Mus musculus (house mouse)IC500.005522
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)IC500.004633
Neuronal acetylcholine receptor subunit alpha-4Gallus gallus (chicken)Ki0.001911
Neuronal acetylcholine receptor subunit alpha-4Homo sapiens (human)Ki0.34443030
Neuronal acetylcholine receptor subunit alpha-4Mus musculus (house mouse)Ki0.001211
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)Ki0.02047285
Neuronal acetylcholine receptor subunit alpha-5Mus musculus (house mouse)IC500.004011
Neuronal acetylcholine receptor subunit alpha-5Rattus norvegicus (Norway rat)IC500.005022
Neuronal acetylcholine receptor subunit alpha-5Mus musculus (house mouse)Ki0.001211
Neuronal acetylcholine receptor subunit alpha-5Rattus norvegicus (Norway rat)Ki0.007034
Neuronal acetylcholine receptor subunit alpha-6Homo sapiens (human)IC500.084811
Neuronal acetylcholine receptor subunit alpha-6Mus musculus (house mouse)IC500.004011
Neuronal acetylcholine receptor subunit alpha-6Rattus norvegicus (Norway rat)IC500.005022
Neuronal acetylcholine receptor subunit alpha-6Mus musculus (house mouse)Ki0.001211
Neuronal acetylcholine receptor subunit alpha-6Rattus norvegicus (Norway rat)Ki0.007034
Neuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)IC5014.300022
Neuronal acetylcholine receptor subunit alpha-7Mus musculus (house mouse)IC500.004011
Neuronal acetylcholine receptor subunit alpha-7Rattus norvegicus (Norway rat)IC500.008733
Neuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)Ki5.93171719
Neuronal acetylcholine receptor subunit alpha-7Mus musculus (house mouse)Ki0.240622
Neuronal acetylcholine receptor subunit alpha-7Rattus norvegicus (Norway rat)Ki3.17291620
Neuronal acetylcholine receptor subunit alpha-9Rattus norvegicus (Norway rat)IC500.004133
Neuronal acetylcholine receptor subunit alpha-9Rattus norvegicus (Norway rat)Ki0.007034
Neuronal acetylcholine receptor subunit beta-2Homo sapiens (human)IC500.32561113
Neuronal acetylcholine receptor subunit beta-2Mus musculus (house mouse)IC500.004011
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)IC500.004633
Neuronal acetylcholine receptor subunit beta-2Homo sapiens (human)Ki0.33993030
Neuronal acetylcholine receptor subunit beta-2Mus musculus (house mouse)Ki0.002422
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)Ki0.01247685
Neuronal acetylcholine receptor subunit beta-3Homo sapiens (human)IC500.084811
Neuronal acetylcholine receptor subunit beta-3Mus musculus (house mouse)IC500.004011
Neuronal acetylcholine receptor subunit beta-3Rattus norvegicus (Norway rat)IC500.005022
Neuronal acetylcholine receptor subunit beta-3Mus musculus (house mouse)Ki0.001211
Neuronal acetylcholine receptor subunit beta-3Rattus norvegicus (Norway rat)Ki0.007034
Neuronal acetylcholine receptor subunit beta-4Homo sapiens (human)IC500.715022
Neuronal acetylcholine receptor subunit beta-4Mus musculus (house mouse)IC500.004011
Neuronal acetylcholine receptor subunit beta-4Rattus norvegicus (Norway rat)IC505.002544
Neuronal acetylcholine receptor subunit beta-4Homo sapiens (human)Ki0.34632222
Neuronal acetylcholine receptor subunit beta-4Mus musculus (house mouse)Ki0.057233
Neuronal acetylcholine receptor subunit beta-4Rattus norvegicus (Norway rat)Ki0.17485463
Neuronal proto-oncogene tyrosine-protein kinase Src Mus musculus (house mouse)IC502.200011
Neutrophil elastaseHomo sapiens (human)IC5012.700011
Neutrophil elastaseHomo sapiens (human)Ki10.100011
NT-3 growth factor receptorHomo sapiens (human)IC501.000011
NUAK family SNF1-like kinase 1Homo sapiens (human)IC5015.024022
Oxoeicosanoid receptor 1Homo sapiens (human)IC500.003011
Pancreatic alpha-amylaseSus scrofa (pig)IC50200.000011
PAS domain-containing serine/threonine-protein kinaseHomo sapiens (human)IC5030.000011
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1Homo sapiens (human)IC5010.000011
perilipin-1Homo sapiens (human)IC509.167011
perilipin-5Homo sapiens (human)IC5010.232011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformHomo sapiens (human)IC5011.000011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformHomo sapiens (human)IC5050.000011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformHomo sapiens (human)IC5012.000011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)IC501,458.500022
Phosphodiesterase Bos taurus (cattle)IC50250.333366
Phosphodiesterase Bos taurus (cattle)Ki77.000011
Phospholipase A-2-activating proteinHomo sapiens (human)IC505.000012
Phospholipase A2Homo sapiens (human)IC5011.100011
Phosphorylase b kinase gamma catalytic chain, liver/testis isoformHomo sapiens (human)IC5030.000011
Platelet-activating factor receptorCavia porcellus (domestic guinea pig)IC50200.000011
Platelet-derived growth factor receptor alphaHomo sapiens (human)GI500.330522
Platelet-derived growth factor receptor alphaHomo sapiens (human)IC506.048855
Platelet-derived growth factor receptor alpha Mus musculus (house mouse)IC500.018677
Platelet-derived growth factor receptor betaHomo sapiens (human)GI500.114011
Platelet-derived growth factor receptor betaHomo sapiens (human)IC5012.62752325
Platelet-derived growth factor receptor betaMus musculus (house mouse)IC500.018677
Platelet-derived growth factor receptor betaHomo sapiens (human)Ki0.008011
Poly [ADP-ribose] polymerase 1Homo sapiens (human)IC504.232912
Poly [ADP-ribose] polymerase tankyrase-1Homo sapiens (human)IC502.399412
Poly [ADP-ribose] polymerase tankyrase-2Homo sapiens (human)IC501.085812
Polyamine deacetylase HDAC10Homo sapiens (human)IC50187.000011
Polyphenol oxidase 2Agaricus bisporusIC50400.000011
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)IC5014.342544
Polyunsaturated fatty acid 5-lipoxygenaseRattus norvegicus (Norway rat)IC505.000044
Polyunsaturated fatty acid lipoxygenase ALOX12Homo sapiens (human)IC5015.000011
Polyunsaturated fatty acid lipoxygenase ALOX15Homo sapiens (human)IC5010.043333
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)IC5025.000011
Polyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)IC5070.000022
Potassium voltage-gated channel subfamily D member 3Homo sapiens (human)IC5050.118711
Potassium voltage-gated channel subfamily E member 1Homo sapiens (human)IC5063.095711
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)IC50132.47321112
Potassium voltage-gated channel subfamily KQT member 1Homo sapiens (human)IC5063.095711
Programmed cell death 1 ligand 1Homo sapiens (human)IC500.010011
Programmed cell death protein 1Homo sapiens (human)IC500.010011
Prostaglandin E synthaseHomo sapiens (human)IC501.800033
Prostaglandin G/H synthase 1Homo sapiens (human)IC5029.416522
Prostaglandin G/H synthase 1Ovis aries (sheep)IC5033.430034
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)IC503.525022
Prostaglandin G/H synthase 2Homo sapiens (human)IC5042.620056
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)IC503.525022
Proteasome subunit beta type-5Homo sapiens (human)IC505.700044
Protein cereblonHomo sapiens (human)IC507.2078611
Protein cereblonHomo sapiens (human)Ki9.263323
Protein delta homolog 1Homo sapiens (human)Ki0.006311
Protein kinase C alpha typeHomo sapiens (human)IC5030.000011
Protein kinase C beta typeHomo sapiens (human)IC5023.450022
Protein kinase C delta typeHomo sapiens (human)IC501.900011
Protein kinase C eta typeHomo sapiens (human)IC5030.000011
Protein kinase C gamma typeHomo sapiens (human)IC5030.000011
Protein kinase C theta typeHomo sapiens (human)IC5030.000011
Protein-tyrosine kinase 2-betaHomo sapiens (human)IC504.300033
Protein-tyrosine kinase 6Homo sapiens (human)IC5030.000011
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)IC500.397177
Proto-oncogene tyrosine-protein kinase ROSHomo sapiens (human)IC5030.000011
Proto-oncogene tyrosine-protein kinase SrcGallus gallus (chicken)IC500.555011
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)IC5011.850933
RAC-alpha serine/threonine-protein kinaseHomo sapiens (human)IC5016.533333
RAC-beta serine/threonine-protein kinaseHomo sapiens (human)IC5030.000011
RAC-gamma serine/threonine-protein kinaseHomo sapiens (human)IC5030.000011
RAF proto-oncogene serine/threonine-protein kinaseHomo sapiens (human)IC503.450044
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)IC5010.664522
Receptor tyrosine-protein kinase erbB-4Homo sapiens (human)IC5030.000011
Receptor-interacting serine/threonine-protein kinase 2Homo sapiens (human)IC5010.000011
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)IC501.16012929
ReninHomo sapiens (human)Ki2.325012
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2IC5045.875014
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirusIC5040.700025
Rho-associated protein kinase 1Homo sapiens (human)IC5030.000011
Rho-associated protein kinase 2Homo sapiens (human)IC5030.000011
Ribonucleoside-diphosphate reductase large subunitHomo sapiens (human)IC50997.000011
Ribosomal protein S6 kinase alpha-1Homo sapiens (human)IC5015.065622
Ribosomal protein S6 kinase alpha-3Homo sapiens (human)IC500.183911
Ribosomal protein S6 kinase alpha-4Homo sapiens (human)IC5030.000011
Ribosomal protein S6 kinase alpha-5Homo sapiens (human)IC5030.000011
Ribosomal protein S6 kinase beta-1Homo sapiens (human)IC5030.000011
RocRPseudomonas aeruginosa PAO1IC500.020011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1Oryctolagus cuniculus (rabbit)IC503.000011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1Oryctolagus cuniculus (rabbit)Ki5.800011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2Homo sapiens (human)IC507.000011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2Homo sapiens (human)Ki53.000011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Rattus norvegicus (Norway rat)Ki5.800011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3Homo sapiens (human)IC507.000011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3Homo sapiens (human)Ki8.600011
Seed linoleate 13S-lipoxygenase-1Glycine max (soybean)IC503.200033
Seed linoleate 13S-lipoxygenase-1Glycine max (soybean)Ki121.700011
Serine/threonine-protein kinase 10Homo sapiens (human)IC501.000011
Serine/threonine-protein kinase 17AHomo sapiens (human)IC5030.000011
Serine/threonine-protein kinase 3Homo sapiens (human)IC5030.000011
Serine/threonine-protein kinase 33Homo sapiens (human)IC5030.000011
Serine/threonine-protein kinase 4Homo sapiens (human)IC5030.000011
Serine/threonine-protein kinase B-rafHomo sapiens (human)IC500.083411
Serine/threonine-protein kinase BRSK1Homo sapiens (human)IC5030.000011
Serine/threonine-protein kinase Chk1Homo sapiens (human)IC5015.038622
Serine/threonine-protein kinase Chk2Homo sapiens (human)IC509.508422
Serine/threonine-protein kinase D1Homo sapiens (human)IC5030.000011
Serine/threonine-protein kinase D2Homo sapiens (human)IC5030.000011
Serine/threonine-protein kinase MARK1Homo sapiens (human)IC5030.000011
Serine/threonine-protein kinase MARK2Homo sapiens (human)IC5043.000011
Serine/threonine-protein kinase MRCK betaHomo sapiens (human)IC501.000011
Serine/threonine-protein kinase mTORHomo sapiens (human)IC5050.000011
Serine/threonine-protein kinase Nek2Homo sapiens (human)IC5012.000011
Serine/threonine-protein kinase Nek3Homo sapiens (human)IC5030.000011
Serine/threonine-protein kinase NLKHomo sapiens (human)IC5030.000011
Serine/threonine-protein kinase PAK 1Homo sapiens (human)IC5016.000011
Serine/threonine-protein kinase PAK 2Homo sapiens (human)IC5030.000011
Serine/threonine-protein kinase PAK 3Homo sapiens (human)IC5030.000011
Serine/threonine-protein kinase PAK 4Homo sapiens (human)IC5010.379533
Serine/threonine-protein kinase PAK 4Homo sapiens (human)Ki0.500011
Serine/threonine-protein kinase PAK 5Homo sapiens (human)IC5030.000011
Serine/threonine-protein kinase PAK 5Homo sapiens (human)Ki0.500011
Serine/threonine-protein kinase PAK 6Homo sapiens (human)IC5030.000011
Serine/threonine-protein kinase PAK 6Homo sapiens (human)Ki0.500011
Serine/threonine-protein kinase pim-1Homo sapiens (human)IC5015.800022
Serine/threonine-protein kinase pim-2Homo sapiens (human)IC5030.000011
Serine/threonine-protein kinase PLK1Homo sapiens (human)IC5020.000022
Serine/threonine-protein kinase PLK1Homo sapiens (human)Ki12.400014
Serine/threonine-protein kinase PLK2Homo sapiens (human)IC5030.000011
Serine/threonine-protein kinase PLK2Homo sapiens (human)Ki12.400014
Serine/threonine-protein kinase PLK3Homo sapiens (human)IC5030.000011
Serine/threonine-protein kinase PLK3Homo sapiens (human)Ki12.400014
Serine/threonine-protein kinase PLK4Homo sapiens (human)Ki12.400014
Serine/threonine-protein kinase Sgk1Homo sapiens (human)IC5030.000011
Serine/threonine-protein kinase TBK1Homo sapiens (human)IC5015.110022
Serine/threonine-protein kinase WNK2Homo sapiens (human)IC5030.000011
Short transient receptor potential channel 5Homo sapiens (human)IC5010.000011
SialidaseClostridium perfringensIC504.300011
Sialidase-2Homo sapiens (human)IC50130.000011
Sigma non-opioid intracellular receptor 1Cavia porcellus (domestic guinea pig)Ki7.900011
Sodium channel protein type 5 subunit alphaHomo sapiens (human)IC5027.829822
Sodium-dependent noradrenaline transporter Homo sapiens (human)IC503.787011
Sodium-dependent noradrenaline transporter Homo sapiens (human)Ki3.756011
Soluble acetylcholine receptorAplysia californica (California sea hare)Ki1.046633
Solute carrier family 22 member 1Rattus norvegicus (Norway rat)Ki64.300011
Solute carrier family 22 member 1 Homo sapiens (human)IC506.100011
Solute carrier family 22 member 2Rattus norvegicus (Norway rat)Ki50.500011
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)IC500.524811
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)Ki0.290011
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)IC500.549511
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)Ki0.420011
Sortase AStreptococcus mutansIC5010.200011
STE20-like serine/threonine-protein kinase Homo sapiens (human)IC505.500022
Stromelysin-1Homo sapiens (human)IC5016.200011
Substance-K receptorCavia porcellus (domestic guinea pig)IC5033.700011
Substance-P receptorCavia porcellus (domestic guinea pig)IC5033.700011
Testis-specific serine/threonine-protein kinase 2Homo sapiens (human)IC5030.000011
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1Homo sapiens (human)IC500.900011
Thioredoxin reductase 1, cytoplasmicHomo sapiens (human)IC5040.466733
Thioredoxin reductase 2, mitochondrialHomo sapiens (human)IC5040.466733
Thioredoxin reductase 3Homo sapiens (human)IC5040.466733
Thiosulfate sulfurtransferaseHomo sapiens (human)IC5056.000011
Thyroid hormone receptor betaRattus norvegicus (Norway rat)Ki14.000011
Tissue factorHomo sapiens (human)IC500.013211
toll-like receptor 9Homo sapiens (human)IC508.362011
TPA: protein transporter TIM10Saccharomyces cerevisiae S288CIC5019.700011
TRAF2 and NCK-interacting protein kinaseHomo sapiens (human)IC505.500022
Transcription factor GATA-4 Mus musculus (house mouse)IC5022.000011
Translocator proteinRattus norvegicus (Norway rat)IC500.039012
Translocator proteinRattus norvegicus (Norway rat)Ki0.506324
TransporterRattus norvegicus (Norway rat)Ki2.750022
TransthyretinHomo sapiens (human)IC506.400011
TyrosinaseHomo sapiens (human)IC5032.500022
Tyrosine-protein kinase ABL1Homo sapiens (human)IC5018.705455
Tyrosine-protein kinase ABL1Mus musculus (house mouse)IC5014.600011
Tyrosine-protein kinase ABL2Homo sapiens (human)IC5030.000011
Tyrosine-protein kinase BlkHomo sapiens (human)IC5015.500022
Tyrosine-protein kinase BTKHomo sapiens (human)IC5030.000011
Tyrosine-protein kinase CSKHomo sapiens (human)IC5030.000011
Tyrosine-protein kinase FerHomo sapiens (human)IC5017.000011
Tyrosine-protein kinase Fes/FpsHomo sapiens (human)IC5030.000011
Tyrosine-protein kinase FgrHomo sapiens (human)IC508.500011
Tyrosine-protein kinase FRKHomo sapiens (human)IC501.000011
Tyrosine-protein kinase FynHomo sapiens (human)IC5015.842855
Tyrosine-protein kinase HCKHomo sapiens (human)IC506.963333
Tyrosine-protein kinase JAK2Homo sapiens (human)IC5030.000011
Tyrosine-protein kinase JAK3Homo sapiens (human)IC5030.000011
Tyrosine-protein kinase LckHomo sapiens (human)IC5010.166066
Tyrosine-protein kinase LynHomo sapiens (human)IC500.960011
Tyrosine-protein kinase receptor Tie-1Homo sapiens (human)IC501.000011
Tyrosine-protein kinase receptor UFOHomo sapiens (human)IC5010.006033
Tyrosine-protein kinase SYKHomo sapiens (human)IC5020.666733
Tyrosine-protein kinase YesHomo sapiens (human)IC508.900011
Tyrosine-protein kinase YesHomo sapiens (human)Ki2.380011
Tyrosine-protein kinase ZAP-70Homo sapiens (human)IC5025.000022
Tyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)IC5032.900022
Tyrosine-protein phosphatase non-receptor type 11Homo sapiens (human)IC509.600022
Tyrosine-protein phosphatase non-receptor type 2Homo sapiens (human)IC5020.000011
Tyrosine-protein phosphatase non-receptor type 6Homo sapiens (human)IC5065.400011
Tyrosine-protein phosphatase non-receptor type 7Homo sapiens (human)IC50300.000011
UDP-glucuronosyltransferase 1A1 Homo sapiens (human)Ki11.300022
UDP-glucuronosyltransferase 1A10Homo sapiens (human)Ki121.300011
UDP-glucuronosyltransferase 1A7Homo sapiens (human)Ki101.000011
UDP-glucuronosyltransferase 1A8Homo sapiens (human)Ki23.000022
UDP-glucuronosyltransferase 1A9Homo sapiens (human)Ki534.000011
Urease subunit alphaHelicobacter pylori 26695IC5067.700022
Urease subunit betaHelicobacter pylori 26695IC5067.700022
Vascular endothelial growth factor receptor 1 Homo sapiens (human)IC500.335444
Vascular endothelial growth factor receptor 1 Homo sapiens (human)Ki0.002011
Vascular endothelial growth factor receptor 2Homo sapiens (human)GI500.033011
Vascular endothelial growth factor receptor 2Homo sapiens (human)IC503.71055860
Vascular endothelial growth factor receptor 2Homo sapiens (human)Ki0.007544
Vascular endothelial growth factor receptor 3Homo sapiens (human)IC500.139522
Vascular endothelial growth factor receptor 3Homo sapiens (human)Ki0.017011
Vitamin D3 receptorBos taurus (cattle)IC500.000011
Vitamin D3 receptorHomo sapiens (human)IC500.34011919
Vitamin D3 receptorRattus norvegicus (Norway rat)Ki0.00011111
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)IC50104.119633
Voltage-dependent L-type calcium channel subunit alpha-1CRattus norvegicus (Norway rat)IC50100.000011
Voltage-dependent L-type calcium channel subunit alpha-1DRattus norvegicus (Norway rat)IC50100.000011
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)IC5033.400011
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)IC5033.400011
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)IC5033.400011
Voltage-dependent L-type calcium channel subunit alpha-1SRattus norvegicus (Norway rat)IC50100.000011
Xanthine dehydrogenase/oxidaseBos taurus (cattle)IC5010.200011
Xanthine dehydrogenase/oxidaseHomo sapiens (human)IC506.630033
Xanthine dehydrogenase/oxidaseBos taurus (cattle)Ki1.900011
Xanthine dehydrogenase/oxidaseHomo sapiens (human)Ki2.900011

Activation Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialHomo sapiens (human)EC500.003011
26S proteasome regulatory subunit 6BHomo sapiens (human)Kd30.000012
3-phosphoinositide-dependent protein kinase 1Homo sapiens (human)Kd6.100035
5-hydroxytryptamine receptor 4Homo sapiens (human)EC5010.000011
5'-AMP-activated protein kinase catalytic subunit alpha-1Homo sapiens (human)Kd2.655068
5'-AMP-activated protein kinase catalytic subunit alpha-2Homo sapiens (human)Kd4.053435
5'-AMP-activated protein kinase subunit gamma-1Homo sapiens (human)Kd1.140011
5'-AMP-activated protein kinase subunit gamma-2Homo sapiens (human)Kd1.734011
AarF domain-containing protein kinase 1Homo sapiens (human)Kd30.000012
Acetylcholine receptor subunit alphaHomo sapiens (human)EC5025.333333
Acetylcholine receptor subunit alphaTetronarce californica (Pacific electric ray)EC5060.000011
Acetylcholine receptor subunit betaHomo sapiens (human)EC5029.000033
Acetylcholine receptor subunit betaTetronarce californica (Pacific electric ray)EC5060.000011
Acetylcholine receptor subunit deltaHomo sapiens (human)EC5033.000022
Acetylcholine receptor subunit deltaTetronarce californica (Pacific electric ray)EC50110.000022
Acetylcholine receptor subunit epsilonHomo sapiens (human)EC5065.000011
Acetylcholine receptor subunit gammaHomo sapiens (human)EC5033.000022
Acetylcholine receptor subunit gammaTetronarce californica (Pacific electric ray)EC5060.000011
Acetylcholine-binding proteinLymnaea stagnalis (great pond snail)Kd0.293135
Actin-related protein 2Homo sapiens (human)Kd30.000011
Actin-related protein 3Homo sapiens (human)Kd30.000011
Activated CDC42 kinase 1Homo sapiens (human)Kd11.666746
Activin receptor type-1Homo sapiens (human)Kd15.714347
Activin receptor type-1BHomo sapiens (human)Kd13.333346
Activin receptor type-2AHomo sapiens (human)Kd10.000035
Activin receptor type-2BHomo sapiens (human)Kd13.333346
Acyl-CoA dehydrogenase family member 11Homo sapiens (human)Kd30.000011
Adenine phosphoribosyltransferaseHomo sapiens (human)Kd30.000011
Adenosine kinaseHomo sapiens (human)Kd30.000011
Adenosine receptor A1Homo sapiens (human)Kd12.000011
Adenosine receptor A2aHomo sapiens (human)EC5028.200011
Adenosine receptor A2aHomo sapiens (human)Kd2.811533
Adenylate kinase 2, mitochondrialHomo sapiens (human)Kd30.000011
ADP/ATP translocase 2Homo sapiens (human)Kd30.000011
ADP/ATP translocase 3Homo sapiens (human)Kd30.000011
ALK tyrosine kinase receptorHomo sapiens (human)Kd4.102035
Alpha-synucleinHomo sapiens (human)Kd3.500044
Alpha-tocopherol transfer proteinHomo sapiens (human)Kd2.420011
Amyloid-beta precursor proteinHomo sapiens (human)EC508.410011
Angiopoietin-1 receptorHomo sapiens (human)Kd5.008546
Angiotensin-converting enzyme 2 Homo sapiens (human)EC5010.600011
Ankyrin repeat and protein kinase domain-containing protein 1Homo sapiens (human)Kd0.586035
AP2-associated protein kinase 1Homo sapiens (human)Kd2.0583810
ATP-dependent 6-phosphofructokinase, platelet typeHomo sapiens (human)Kd30.000011
ATP-dependent RNA helicase DDX1Homo sapiens (human)Kd30.000011
ATP-dependent RNA helicase DDX3XHomo sapiens (human)Kd30.000011
ATP-dependent RNA helicase DDX42Homo sapiens (human)Kd30.000011
ATP-dependent RNA helicase DHX30Homo sapiens (human)Kd30.000011
ATP-dependent translocase ABCB1Homo sapiens (human)EC500.524011
Atypical kinase COQ8A, mitochondrialHomo sapiens (human)Kd13.333346
Atypical kinase COQ8B, mitochondrialHomo sapiens (human)Kd10.000035
Aurora kinase AHomo sapiens (human)Kd8.814357
Aurora kinase BHomo sapiens (human)Kd3.826246
Aurora kinase CHomo sapiens (human)Kd3.040057
BDNF/NT-3 growth factors receptorHomo sapiens (human)Kd0.582035
Beta-adrenergic receptor kinase 1Homo sapiens (human)Kd30.000011
BMP-2-inducible protein kinaseHomo sapiens (human)Kd2.522468
Bone morphogenetic protein receptor type-1AHomo sapiens (human)Kd13.333346
Bone morphogenetic protein receptor type-1BHomo sapiens (human)Kd13.100034
Bone morphogenetic protein receptor type-2Homo sapiens (human)Kd4.053046
Breakpoint cluster region proteinHomo sapiens (human)EC501.000011
Breakpoint cluster region proteinHomo sapiens (human)Kd30.000011
Bromodomain-containing protein 7Homo sapiens (human)Kd11.000011
Bromodomain-containing protein 9Homo sapiens (human)Kd17.000011
calcineurin A1, putativeCandida dubliniensis CD36EC50180.000011
Calcium-dependent protein kinase 1Plasmodium falciparum 3D7Kd5.650012
Calcium/calmodulin-dependent protein kinase kinase 1Homo sapiens (human)Kd3.693346
Calcium/calmodulin-dependent protein kinase kinase 2Homo sapiens (human)Kd8.614357
Calcium/calmodulin-dependent protein kinase type 1Homo sapiens (human)Kd4.151746
Calcium/calmodulin-dependent protein kinase type 1DHomo sapiens (human)Kd3.771746
Calcium/calmodulin-dependent protein kinase type 1GHomo sapiens (human)Kd4.374035
Calcium/calmodulin-dependent protein kinase type II subunit alphaHomo sapiens (human)Kd2.997157
Calcium/calmodulin-dependent protein kinase type II subunit betaHomo sapiens (human)Kd4.566746
Calcium/calmodulin-dependent protein kinase type II subunit deltaHomo sapiens (human)Kd7.480057
Calcium/calmodulin-dependent protein kinase type II subunit gammaHomo sapiens (human)Kd2.769879
Calcium/calmodulin-dependent protein kinase type IVHomo sapiens (human)Kd4.273346
cAMP-dependent protein kinase catalytic subunit alphaHomo sapiens (human)Kd14.000035
cAMP-dependent protein kinase catalytic subunit betaHomo sapiens (human)Kd13.333346
cAMP-dependent protein kinase catalytic subunit gammaHomo sapiens (human)Kd30.000011
cAMP-dependent protein kinase catalytic subunit PRKXHomo sapiens (human)Kd13.333346
cAMP-dependent protein kinase type II-alpha regulatory subunitHomo sapiens (human)Kd30.000011
Casein kinase I isoform alphaHomo sapiens (human)Kd4.497034
Casein kinase I isoform alpha-likeHomo sapiens (human)Kd5.275024
Casein kinase I isoform deltaHomo sapiens (human)Kd3.485746
Casein kinase I isoform epsilonHomo sapiens (human)Kd3.481246
Casein kinase I isoform gamma-1Homo sapiens (human)Kd4.360746
Casein kinase I isoform gamma-2Homo sapiens (human)Kd8.388346
Casein kinase I isoform gamma-3Homo sapiens (human)Kd3.944346
Casein kinase II subunit alphaHomo sapiens (human)Kd4.212435
Casein kinase II subunit alpha'Homo sapiens (human)Kd4.016846
Cell division control protein 2 homologPlasmodium falciparum 3D7Kd10.000012
Cell division cycle 7-related protein kinaseHomo sapiens (human)Kd30.000011
cGMP-dependent protein kinase 1 Homo sapiens (human)Kd13.333346
cGMP-dependent protein kinase 2Homo sapiens (human)Kd10.000035
Chain A, p38 MAP kinaseHomo sapiens (human)Kd0.000112
Chain A, TransthyretinHomo sapiens (human)Kd0.100015
Chain A, Vitamin D Nuclear ReceptorHomo sapiens (human)Kd0.000611
Chain B, TransthyretinHomo sapiens (human)Kd0.100012
Choline-phosphate cytidylyltransferase AHomo sapiens (human)Kd30.000011
Chromodomain-helicase-DNA-binding protein 4Homo sapiens (human)Kd30.000011
Citron Rho-interacting kinaseHomo sapiens (human)Kd7.650046
Cyclin-dependent kinase 1Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 10Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 11AHomo sapiens (human)Kd10.000035
Cyclin-dependent kinase 11BHomo sapiens (human)Kd10.000035
Cyclin-dependent kinase 12Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 13Homo sapiens (human)Kd13.700023
Cyclin-dependent kinase 14Homo sapiens (human)Kd4.162035
Cyclin-dependent kinase 15Homo sapiens (human)Kd10.000023
Cyclin-dependent kinase 16Homo sapiens (human)Kd2.882968
Cyclin-dependent kinase 17Homo sapiens (human)Kd4.413346
Cyclin-dependent kinase 18Homo sapiens (human)Kd9.183346
Cyclin-dependent kinase 19Homo sapiens (human)Kd6.080035
Cyclin-dependent kinase 2Homo sapiens (human)Kd12.857157
Cyclin-dependent kinase 3Homo sapiens (human)Kd8.504046
Cyclin-dependent kinase 4Homo sapiens (human)Kd11.640035
Cyclin-dependent kinase 6Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 7Homo sapiens (human)Kd2.548746
Cyclin-dependent kinase 8Homo sapiens (human)Kd6.088035
Cyclin-dependent kinase 9Homo sapiens (human)Kd13.333346
Cyclin-dependent kinase-like 1Homo sapiens (human)Kd10.000012
Cyclin-dependent kinase-like 2Homo sapiens (human)Kd4.066723
Cyclin-dependent kinase-like 3Homo sapiens (human)Kd10.000023
Cyclin-dependent kinase-like 5Homo sapiens (human)Kd18.000035
Cyclin-dependent-like kinase 5 Homo sapiens (human)Kd8.755757
Cyclin-G-associated kinaseHomo sapiens (human)Kd2.400879
Cysteine--tRNA ligase, cytoplasmicHomo sapiens (human)Kd30.000011
Cytochrome c1, heme protein, mitochondrialHomo sapiens (human)Kd30.000011
Cytochrome P450 2A13Homo sapiens (human)Kd54.000011
Cytochrome P450 2A6Homo sapiens (human)Kd470.000011
Cytoplasmic tyrosine-protein kinase BMXHomo sapiens (human)Kd10.000035
dCTP pyrophosphatase 1Homo sapiens (human)Kd30.000011
Death-associated protein kinase 1Homo sapiens (human)Kd4.072035
Death-associated protein kinase 2Homo sapiens (human)Kd3.055757
Death-associated protein kinase 3Homo sapiens (human)Kd3.418469
Delta(24)-sterol reductaseHomo sapiens (human)Kd30.000012
Deoxycytidine kinaseHomo sapiens (human)Kd30.000011
Discoidin domain-containing receptor 2Homo sapiens (human)Kd5.894879
DNA damage-binding protein 1Homo sapiens (human)EC500.009011
DNA replication licensing factor MCM4Homo sapiens (human)Kd30.000011
DNA topoisomerase 2-alphaHomo sapiens (human)Kd30.000011
DNA topoisomerase 2-betaHomo sapiens (human)Kd30.000011
DNA-binding protein IkarosHomo sapiens (human)EC500.045512
DnaJ homolog subfamily A member 1Homo sapiens (human)Kd30.000011
Dual serine/threonine and tyrosine protein kinaseHomo sapiens (human)Kd5.650012
Dual specificity mitogen-activated protein kinase kinase 1Homo sapiens (human)Kd3.828346
Dual specificity mitogen-activated protein kinase kinase 2Homo sapiens (human)Kd3.667846
Dual specificity mitogen-activated protein kinase kinase 3Homo sapiens (human)Kd11.950046
Dual specificity mitogen-activated protein kinase kinase 4Homo sapiens (human)Kd8.140035
Dual specificity mitogen-activated protein kinase kinase 5Homo sapiens (human)Kd4.523723
Dual specificity mitogen-activated protein kinase kinase 6Homo sapiens (human)Kd12.533346
Dual specificity mitogen-activated protein kinase kinase 7Homo sapiens (human)Kd10.000012
Dual specificity protein kinase CLK1Homo sapiens (human)Kd2.303179
Dual specificity protein kinase CLK2Homo sapiens (human)Kd2.375879
Dual specificity protein kinase CLK3Homo sapiens (human)Kd13.333346
Dual specificity protein kinase CLK4Homo sapiens (human)Kd5.586279
Dual specificity protein kinase TTKHomo sapiens (human)Kd4.272169
Dual specificity testis-specific protein kinase 1Homo sapiens (human)Kd13.333346
Dual specificity tyrosine-phosphorylation-regulated kinase 1AHomo sapiens (human)Kd3.518834
Dual specificity tyrosine-phosphorylation-regulated kinase 1BHomo sapiens (human)Kd5.380035
Dual specificity tyrosine-phosphorylation-regulated kinase 2Homo sapiens (human)Kd3.786723
Dynamin-like 120 kDa protein, mitochondrialHomo sapiens (human)Kd30.000011
Egl nine homolog 1Homo sapiens (human)EC5050.000011
eIF-2-alpha kinase GCN2Homo sapiens (human)Kd4.108035
EKC/KEOPS complex subunit TP53RKHomo sapiens (human)Kd30.000011
Electron transfer flavoprotein subunit betaHomo sapiens (human)Kd30.000011
Elongation factor Tu, mitochondrialHomo sapiens (human)Kd30.000011
Ephrin type-A receptor 1Homo sapiens (human)Kd13.266746
Ephrin type-A receptor 2Homo sapiens (human)Kd10.785757
Ephrin type-A receptor 3Homo sapiens (human)Kd1.440046
Ephrin type-A receptor 4Homo sapiens (human)Kd9.957157
Ephrin type-A receptor 5Homo sapiens (human)Kd7.650058
Ephrin type-A receptor 6Homo sapiens (human)Kd1.330047
Ephrin type-A receptor 7Homo sapiens (human)Kd4.506769
Ephrin type-A receptor 8Homo sapiens (human)Kd5.113346
Ephrin type-B receptor 1Homo sapiens (human)Kd2.170058
Ephrin type-B receptor 2Homo sapiens (human)Kd10.146746
Ephrin type-B receptor 3Homo sapiens (human)Kd13.333346
Ephrin type-B receptor 4Homo sapiens (human)Kd13.162558
Ephrin type-B receptor 6Homo sapiens (human)Kd10.462534
Epidermal growth factor receptorHomo sapiens (human)Kd8.60492951
Epithelial discoidin domain-containing receptor 1Homo sapiens (human)Kd4.750768
Eukaryotic translation initiation factor 2-alpha kinase 1Homo sapiens (human)Kd16.666723
Eukaryotic translation initiation factor 5BHomo sapiens (human)Kd30.000011
Exosome RNA helicase MTR4Homo sapiens (human)Kd30.000011
Ferrochelatase, mitochondrialHomo sapiens (human)Kd30.000011
Fibroblast growth factor receptor 1Homo sapiens (human)Kd2.222157
Fibroblast growth factor receptor 2Homo sapiens (human)Kd3.252957
Fibroblast growth factor receptor 3Homo sapiens (human)Kd4.1245711
Fibroblast growth factor receptor 4Homo sapiens (human)Kd8.420035
Focal adhesion kinase 1Homo sapiens (human)Kd5.842568
G protein-coupled receptor kinase 4Homo sapiens (human)Kd3.426723
G protein-coupled receptor kinase 6Homo sapiens (human)Kd1.615011
G-protein coupled receptor 35Homo sapiens (human)EC505.220022
General transcription and DNA repair factor IIH helicase subunit XPDHomo sapiens (human)Kd1.225011
Glycine--tRNA ligaseHomo sapiens (human)Kd30.000011
Glycogen phosphorylase, brain formHomo sapiens (human)Kd30.000011
Glycogen phosphorylase, liver formHomo sapiens (human)Kd30.000011
Glycogen synthase kinase-3 alphaHomo sapiens (human)Kd13.333346
Glycogen synthase kinase-3 betaHomo sapiens (human)Kd13.333346
glycogen synthase kinase-3 beta isoform 1Homo sapiens (human)EC503.812011
Glycoprotein IIbOryctolagus cuniculus (rabbit)EC501.506814
GTP-binding nuclear protein RanHomo sapiens (human)Kd30.000011
Guanine nucleotide-binding protein G(i) subunit alpha-2Homo sapiens (human)Kd30.000011
heat shock protein 90Candida albicansEC50120.033034
Heme oxygenase 2Homo sapiens (human)Kd30.000011
Hepatocyte growth factor receptorHomo sapiens (human)Kd9.0833812
High affinity nerve growth factor receptorHomo sapiens (human)Kd0.5550710
Homeodomain-interacting protein kinase 1Homo sapiens (human)Kd6.685023
Homeodomain-interacting protein kinase 2Homo sapiens (human)Kd3.354023
Homeodomain-interacting protein kinase 3Homo sapiens (human)Kd3.360723
Homeodomain-interacting protein kinase 4Homo sapiens (human)Kd3.440023
Hormonally up-regulated neu tumor-associated kinaseHomo sapiens (human)Kd3.666723
Inhibitor of nuclear factor kappa-B kinase subunit alphaHomo sapiens (human)Kd3.680023
Inhibitor of nuclear factor kappa-B kinase subunit betaHomo sapiens (human)Kd10.000023
Inhibitor of nuclear factor kappa-B kinase subunit epsilonHomo sapiens (human)Kd3.931846
Inosine-5'-monophosphate dehydrogenase 2Homo sapiens (human)Kd30.000011
Insulin receptorHomo sapiens (human)Kd6.482568
Insulin receptor-related proteinHomo sapiens (human)Kd4.258035
Insulin-like growth factor 1 receptorHomo sapiens (human)Kd9.633346
Integrin betaOryctolagus cuniculus (rabbit)EC501.506814
Integrin-linked protein kinaseHomo sapiens (human)Kd30.000011
Interferon-induced, double-stranded RNA-activated protein kinaseHomo sapiens (human)Kd4.402035
Interleukin-1 receptor-associated kinase 1Homo sapiens (human)Kd10.007034
Interleukin-1 receptor-associated kinase 3Homo sapiens (human)Kd8.803346
Interleukin-1 receptor-associated kinase 4Homo sapiens (human)Kd4.230323
Isoleucine--tRNA ligase, mitochondrialHomo sapiens (human)Kd30.000011
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)EC500.000011
Kelch-like ECH-associated protein 1Homo sapiens (human)EC505.110011
large T antigenBetapolyomavirus macacaeEC5047.930011
Leucine-rich repeat serine/threonine-protein kinase 2Homo sapiens (human)Kd5.046524
Leukocyte tyrosine kinase receptorHomo sapiens (human)Kd1.640035
Leukotriene B4 receptor 1Homo sapiens (human)EC500.070011
Leukotriene B4 receptor 2Homo sapiens (human)EC500.070011
Leukotriene C4 synthaseCavia porcellus (domestic guinea pig)Kd5.465012
LIM domain kinase 1Homo sapiens (human)Kd15.714347
LIM domain kinase 2Homo sapiens (human)Kd13.333346
Long-chain-fatty-acid--CoA ligase 5Homo sapiens (human)Kd30.000011
Lymphocyte antigen 96Homo sapiens (human)Kd379.000011
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)Kd3.241335
Macrophage-stimulating protein receptorHomo sapiens (human)Kd15.000034
MAP kinase-activated protein kinase 2Homo sapiens (human)Kd13.333346
MAP kinase-activated protein kinase 5Homo sapiens (human)Kd13.333346
MAP kinase-interacting serine/threonine-protein kinase 1Homo sapiens (human)Kd8.040035
MAP kinase-interacting serine/threonine-protein kinase 2Homo sapiens (human)Kd5.000046
MAP/microtubule affinity-regulating kinase 3Homo sapiens (human)Kd3.491057
MAP/microtubule affinity-regulating kinase 4Homo sapiens (human)Kd10.133346
Mast/stem cell growth factor receptor KitHomo sapiens (human)Kd1.85612462
Maternal embryonic leucine zipper kinaseHomo sapiens (human)Kd3.733846
Megakaryocyte-associated tyrosine-protein kinaseHomo sapiens (human)Kd9.233323
Membrane-associated progesterone receptor component 1Homo sapiens (human)Kd30.000011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinaseHomo sapiens (human)Kd13.333346
Microtubule-associated serine/threonine-protein kinase 1Homo sapiens (human)Kd3.466723
MidasinHomo sapiens (human)Kd30.000012
Misshapen-like kinase 1Homo sapiens (human)Kd0.122723
Mitogen-activated protein kinase 1Homo sapiens (human)Kd13.333346
Mitogen-activated protein kinase 10Homo sapiens (human)Kd6.830568
Mitogen-activated protein kinase 11Homo sapiens (human)EC500.018011
Mitogen-activated protein kinase 11Homo sapiens (human)Kd6.858669
Mitogen-activated protein kinase 12Homo sapiens (human)EC500.018011
Mitogen-activated protein kinase 12Homo sapiens (human)Kd3.754558
Mitogen-activated protein kinase 13Homo sapiens (human)EC500.018011
Mitogen-activated protein kinase 13Homo sapiens (human)Kd4.015635
Mitogen-activated protein kinase 14Homo sapiens (human)EC500.018011
Mitogen-activated protein kinase 14Homo sapiens (human)Kd2.72841922
Mitogen-activated protein kinase 14 Mus musculus (house mouse)Kd0.000133
Mitogen-activated protein kinase 15Homo sapiens (human)Kd11.000046
Mitogen-activated protein kinase 3 Homo sapiens (human)Kd13.333346
Mitogen-activated protein kinase 4Homo sapiens (human)Kd10.000035
Mitogen-activated protein kinase 6Homo sapiens (human)Kd10.000035
Mitogen-activated protein kinase 7Homo sapiens (human)Kd13.316746
Mitogen-activated protein kinase 8Homo sapiens (human)Kd13.183346
Mitogen-activated protein kinase 9Homo sapiens (human)Kd6.553168
Mitogen-activated protein kinase kinase kinase 1Homo sapiens (human)Kd15.000034
Mitogen-activated protein kinase kinase kinase 10Homo sapiens (human)Kd10.000035
Mitogen-activated protein kinase kinase kinase 11Homo sapiens (human)Kd4.499546
Mitogen-activated protein kinase kinase kinase 12Homo sapiens (human)Kd5.050012
Mitogen-activated protein kinase kinase kinase 13Homo sapiens (human)Kd3.396723
Mitogen-activated protein kinase kinase kinase 15Homo sapiens (human)Kd4.200023
Mitogen-activated protein kinase kinase kinase 19Homo sapiens (human)Kd3.344723
Mitogen-activated protein kinase kinase kinase 2Homo sapiens (human)Kd3.125234
Mitogen-activated protein kinase kinase kinase 20Homo sapiens (human)Kd10.286746
Mitogen-activated protein kinase kinase kinase 3Homo sapiens (human)Kd3.426034
Mitogen-activated protein kinase kinase kinase 4Homo sapiens (human)Kd11.157157
Mitogen-activated protein kinase kinase kinase 5Homo sapiens (human)Kd13.333346
Mitogen-activated protein kinase kinase kinase 6Homo sapiens (human)Kd15.000034
Mitogen-activated protein kinase kinase kinase 7Homo sapiens (human)Kd0.112023
Mitogen-activated protein kinase kinase kinase 9Homo sapiens (human)Kd6.040035
Mitogen-activated protein kinase kinase kinase kinase 1Homo sapiens (human)Kd3.382846
Mitogen-activated protein kinase kinase kinase kinase 2Homo sapiens (human)Kd12.508234
Mitogen-activated protein kinase kinase kinase kinase 3Homo sapiens (human)Kd3.511346
Mitogen-activated protein kinase kinase kinase kinase 4Homo sapiens (human)Kd0.144746
Mitogen-activated protein kinase kinase kinase kinase 5Homo sapiens (human)Kd2.683968
Mitotic checkpoint serine/threonine-protein kinase BUB1Homo sapiens (human)Kd3.507011
Multifunctional protein ADE2Homo sapiens (human)Kd30.000011
Muscle, skeletal receptor tyrosine-protein kinaseHomo sapiens (human)Kd1.054035
Myosin light chain kinase 2, skeletal/cardiac muscleHomo sapiens (human)Kd2.894457
Myosin light chain kinase 3Homo sapiens (human)Kd13.341023
Myosin light chain kinase family member 4Homo sapiens (human)Kd4.009035
Myosin light chain kinase, smooth muscleGallus gallus (chicken)Kd5.011512
Myosin light chain kinase, smooth muscleHomo sapiens (human)Kd10.107958
Myosin-10Homo sapiens (human)Kd30.000011
Myosin-14Homo sapiens (human)Kd30.000011
Myosin-IIIaHomo sapiens (human)Kd8.620035
Myosin-IIIbHomo sapiens (human)Kd6.700035
Myotonin-protein kinaseHomo sapiens (human)Kd10.000035
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13Homo sapiens (human)Kd30.000012
Neuronal acetylcholine receptor subunit alpha-10Rattus norvegicus (Norway rat)EC5040.666723
Neuronal acetylcholine receptor subunit alpha-10Rattus norvegicus (Norway rat)Kd14,352.000033
Neuronal acetylcholine receptor subunit alpha-2Rattus norvegicus (Norway rat)EC5035.500022
Neuronal acetylcholine receptor subunit alpha-2Rattus norvegicus (Norway rat)Kd14,352.000033
Neuronal acetylcholine receptor subunit alpha-3Homo sapiens (human)EC5021.32601415
Neuronal acetylcholine receptor subunit alpha-3Rattus norvegicus (Norway rat)EC5030.251778
Neuronal acetylcholine receptor subunit alpha-3Rattus norvegicus (Norway rat)Kd14,352.000033
Neuronal acetylcholine receptor subunit alpha-4Homo sapiens (human)EC503.14242024
Neuronal acetylcholine receptor subunit alpha-4Mus musculus (house mouse)EC500.722212
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)EC5010.73981212
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)Kd14,352.000033
Neuronal acetylcholine receptor subunit alpha-5Homo sapiens (human)EC5030.000011
Neuronal acetylcholine receptor subunit alpha-5Rattus norvegicus (Norway rat)EC5035.500022
Neuronal acetylcholine receptor subunit alpha-5Rattus norvegicus (Norway rat)Kd14,352.000033
Neuronal acetylcholine receptor subunit alpha-6Homo sapiens (human)EC500.127011
Neuronal acetylcholine receptor subunit alpha-6Rattus norvegicus (Norway rat)EC5035.500022
Neuronal acetylcholine receptor subunit alpha-6Rattus norvegicus (Norway rat)Kd14,352.000033
Neuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)EC5055.215866
Neuronal acetylcholine receptor subunit alpha-7Rattus norvegicus (Norway rat)EC503,948.08361011
Neuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)Kd0.001111
Neuronal acetylcholine receptor subunit alpha-7Rattus norvegicus (Norway rat)Kd14,352.000033
Neuronal acetylcholine receptor subunit alpha-9Rattus norvegicus (Norway rat)EC5035.500022
Neuronal acetylcholine receptor subunit alpha-9Rattus norvegicus (Norway rat)Kd14,352.000033
Neuronal acetylcholine receptor subunit beta-2Homo sapiens (human)EC509.31272327
Neuronal acetylcholine receptor subunit beta-2Mus musculus (house mouse)EC500.722212
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)EC5010.73981212
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)Kd14,352.000033
Neuronal acetylcholine receptor subunit beta-3Homo sapiens (human)EC5010.563522
Neuronal acetylcholine receptor subunit beta-3Rattus norvegicus (Norway rat)EC5035.500022
Neuronal acetylcholine receptor subunit beta-3Rattus norvegicus (Norway rat)Kd14,352.000033
Neuronal acetylcholine receptor subunit beta-4Homo sapiens (human)EC5013.65761415
Neuronal acetylcholine receptor subunit beta-4Rattus norvegicus (Norway rat)EC5030.251778
Neuronal acetylcholine receptor subunit beta-4Rattus norvegicus (Norway rat)Kd14,352.000033
Non-receptor tyrosine-protein kinase TNK1Homo sapiens (human)Kd8.673346
Non-receptor tyrosine-protein kinase TYK2Homo sapiens (human)Kd7.280069
NT-3 growth factor receptorHomo sapiens (human)Kd3.136035
NUAK family SNF1-like kinase 1Homo sapiens (human)Kd4.028835
NUAK family SNF1-like kinase 2Homo sapiens (human)Kd8.408346
Nuclear factor erythroid 2-related factor 2Homo sapiens (human)EC5013.055022
Nucleolar GTP-binding protein 1Homo sapiens (human)Kd30.000011
Obg-like ATPase 1Homo sapiens (human)Kd30.000011
Oxoeicosanoid receptor 1Homo sapiens (human)EC500.113522
Palmitoleoyl-protein carboxylesterase NOTUMHomo sapiens (human)Kd6,800.000011
PAS domain-containing serine/threonine-protein kinaseHomo sapiens (human)Kd30.000011
Peripheral plasma membrane protein CASKHomo sapiens (human)Kd10.000012
Peroxisomal acyl-coenzyme A oxidase 1Homo sapiens (human)Kd30.000011
Peroxisomal acyl-coenzyme A oxidase 3Homo sapiens (human)Kd30.000011
Peroxisome proliferator-activated receptor gammaMus musculus (house mouse)EC502.300011
Phenylalanine--tRNA ligase beta subunitHomo sapiens (human)Kd30.000011
Phosphatidylethanolamine-binding protein 1Homo sapiens (human)Kd30.000011
Phosphatidylinositol 4-kinase betaHomo sapiens (human)Kd10.000023
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit betaHomo sapiens (human)Kd10.000023
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gammaHomo sapiens (human)Kd10.000023
Phosphatidylinositol 4-phosphate 5-kinase type-1 alphaHomo sapiens (human)Kd7.240035
Phosphatidylinositol 4-phosphate 5-kinase type-1 gammaHomo sapiens (human)Kd10.000012
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformHomo sapiens (human)Kd10.00002133
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformHomo sapiens (human)Kd10.000023
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformHomo sapiens (human)Kd10.000023
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)Kd10.000023
Phosphatidylinositol 5-phosphate 4-kinase type-2 alphaHomo sapiens (human)Kd30.000011
Phosphatidylinositol 5-phosphate 4-kinase type-2 betaHomo sapiens (human)Kd4.023435
Phosphatidylinositol 5-phosphate 4-kinase type-2 gammaHomo sapiens (human)Kd16.666723
Phosphorylase b kinase gamma catalytic chain, liver/testis isoformHomo sapiens (human)Kd2.594668
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoformHomo sapiens (human)Kd2.879557
Platelet-derived growth factor receptor alphaHomo sapiens (human)Kd0.480535
Platelet-derived growth factor receptor betaHomo sapiens (human)Kd0.356169
Poly [ADP-ribose] polymerase tankyrase-2Homo sapiens (human)Kd8.900011
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)EC500.070011
POsterior SegregationCaenorhabditis elegansEC5060.374011
Potassium channel subfamily K member 2Homo sapiens (human)EC50486.000011
Probable ATP-dependent RNA helicase DDX6Homo sapiens (human)Kd30.000011
Procathepsin LHomo sapiens (human)EC5010.600011
Prolyl hydroxylase EGLN2Homo sapiens (human)EC5050.000011
Prolyl hydroxylase EGLN3Homo sapiens (human)EC5050.000011
Prostaglandin G/H synthase 2Homo sapiens (human)Kd5.017512
Protein cereblonHomo sapiens (human)EC500.041835
Protein delta homolog 1Homo sapiens (human)Kd0.100011
Protein kinase C alpha typeHomo sapiens (human)Kd15.333333
Protein kinase C beta typeHomo sapiens (human)Kd30.000011
Protein kinase C delta typeHomo sapiens (human)Kd13.333346
Protein kinase C epsilon typeHomo sapiens (human)Kd10.000035
Protein kinase C eta typeHomo sapiens (human)Kd8.375046
Protein kinase C iota typeHomo sapiens (human)Kd16.666723
Protein kinase C theta typeHomo sapiens (human)Kd10.483346
Protein kinase C zeta typeHomo sapiens (human)Kd30.000011
Protein polybromo-1Homo sapiens (human)Kd12.900011
Protein-tyrosine kinase 2-betaHomo sapiens (human)Kd8.889447
Protein-tyrosine kinase 6Homo sapiens (human)Kd12.433346
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)Kd1.27271117
Proto-oncogene tyrosine-protein kinase ROSHomo sapiens (human)Kd10.000035
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)Kd8.485757
Putative heat shock protein HSP 90-beta 2Homo sapiens (human)Kd30.000011
Pyridoxal kinaseHomo sapiens (human)Kd6.021011
Rab-like protein 3Homo sapiens (human)Kd30.000011
RAC-alpha serine/threonine-protein kinaseHomo sapiens (human)Kd13.333346
RAC-beta serine/threonine-protein kinaseHomo sapiens (human)Kd9.683346
RAC-gamma serine/threonine-protein kinaseHomo sapiens (human)Kd13.333346
RAF proto-oncogene serine/threonine-protein kinaseHomo sapiens (human)Kd10.000035
Ras-related protein Rab-10Homo sapiens (human)Kd30.000011
Ras-related protein Rab-27AHomo sapiens (human)Kd30.000012
Ras-related protein Rab-6AHomo sapiens (human)Kd30.000011
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)Kd10.000035
Receptor tyrosine-protein kinase erbB-3Homo sapiens (human)Kd10.000023
Receptor tyrosine-protein kinase erbB-4Homo sapiens (human)Kd10.000023
Receptor-interacting serine/threonine-protein kinase 1Homo sapiens (human)Kd3.580046
Receptor-interacting serine/threonine-protein kinase 2Homo sapiens (human)Kd12.633346
Receptor-interacting serine/threonine-protein kinase 3Homo sapiens (human)Kd30.000011
Receptor-interacting serine/threonine-protein kinase 4Homo sapiens (human)Kd4.733323
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)Kd2.10112538
Replicase polyprotein 1aSevere acute respiratory syndrome-related coronavirusEC5010.600022
Replicase polyprotein 1abBetacoronavirus England 1EC5010.600011
Replicase polyprotein 1abHuman coronavirus 229EEC5010.600022
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2EC5010.300022
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirusEC5010.400033
Retinoic acid receptor RXR-alphaHomo sapiens (human)EC500.001611
Rho-associated protein kinase 1Homo sapiens (human)Kd10.230034
Rho-associated protein kinase 2Homo sapiens (human)Kd10.070034
Rhodopsin kinase GRK1Homo sapiens (human)Kd3.526723
Rhodopsin kinase GRK7Homo sapiens (human)Kd3.453323
Ribosomal protein S6 kinase alpha-1Homo sapiens (human)Kd4.8755711
Ribosomal protein S6 kinase alpha-2Homo sapiens (human)Kd4.8898812
Ribosomal protein S6 kinase alpha-3Homo sapiens (human)Kd3.120768
Ribosomal protein S6 kinase alpha-4Homo sapiens (human)Kd4.5367711
Ribosomal protein S6 kinase alpha-5Homo sapiens (human)Kd4.1150913
Ribosomal protein S6 kinase alpha-6Homo sapiens (human)Kd9.7455711
Ribosomal protein S6 kinase beta-1Homo sapiens (human)Kd10.062034
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)Kd4.022011
RNA cytidine acetyltransferaseHomo sapiens (human)Kd30.000011
S-adenosylmethionine synthase isoform type-2Homo sapiens (human)Kd30.000011
Septin-9Homo sapiens (human)Kd30.000012
Serine/threonine-protein kinase 10Homo sapiens (human)Kd0.586658
Serine/threonine-protein kinase 16Homo sapiens (human)Kd6.433868
Serine/threonine-protein kinase 17AHomo sapiens (human)Kd2.863657
Serine/threonine-protein kinase 17BHomo sapiens (human)Kd2.967157
Serine/threonine-protein kinase 24Homo sapiens (human)Kd4.045546
Serine/threonine-protein kinase 25Homo sapiens (human)Kd4.174035
Serine/threonine-protein kinase 26Homo sapiens (human)Kd3.875746
Serine/threonine-protein kinase 3Homo sapiens (human)Kd3.761846
Serine/threonine-protein kinase 3Mus musculus (house mouse)Kd0.160011
Serine/threonine-protein kinase 32AHomo sapiens (human)Kd10.000012
Serine/threonine-protein kinase 32BHomo sapiens (human)Kd10.000035
Serine/threonine-protein kinase 32CHomo sapiens (human)Kd10.000035
Serine/threonine-protein kinase 33Homo sapiens (human)Kd4.010235
Serine/threonine-protein kinase 35Homo sapiens (human)Kd4.200023
Serine/threonine-protein kinase 36Homo sapiens (human)Kd10.000035
Serine/threonine-protein kinase 38Homo sapiens (human)Kd3.606723
Serine/threonine-protein kinase 38-likeHomo sapiens (human)Kd7.772957
Serine/threonine-protein kinase 4Homo sapiens (human)Kd2.698268
Serine/threonine-protein kinase A-RafHomo sapiens (human)Kd30.000011
Serine/threonine-protein kinase ATRHomo sapiens (human)Kd30.000011
Serine/threonine-protein kinase B-rafHomo sapiens (human)Kd10.4909711
Serine/threonine-protein kinase BRSK1Homo sapiens (human)Kd6.100035
Serine/threonine-protein kinase BRSK2Homo sapiens (human)Kd4.660035
Serine/threonine-protein kinase Chk1Homo sapiens (human)Kd4.032346
Serine/threonine-protein kinase Chk2Homo sapiens (human)Kd3.339023
Serine/threonine-protein kinase D1Homo sapiens (human)Kd4.186035
Serine/threonine-protein kinase D2Homo sapiens (human)Kd3.710846
Serine/threonine-protein kinase D3Homo sapiens (human)Kd3.747546
Serine/threonine-protein kinase DCLK1Homo sapiens (human)Kd4.222035
Serine/threonine-protein kinase DCLK2Homo sapiens (human)Kd5.620035
Serine/threonine-protein kinase DCLK3Homo sapiens (human)Kd4.066035
Serine/threonine-protein kinase ICKHomo sapiens (human)Kd10.235034
Serine/threonine-protein kinase LATS1Homo sapiens (human)Kd3.772246
Serine/threonine-protein kinase LATS2Homo sapiens (human)Kd4.276035
Serine/threonine-protein kinase MAKHomo sapiens (human)Kd10.000023
Serine/threonine-protein kinase MARK1Homo sapiens (human)Kd4.720035
Serine/threonine-protein kinase MARK2Homo sapiens (human)Kd3.466157
Serine/threonine-protein kinase MRCK alphaHomo sapiens (human)Kd13.133346
Serine/threonine-protein kinase MRCK betaHomo sapiens (human)Kd10.303346
Serine/threonine-protein kinase MRCK gammaHomo sapiens (human)Kd10.400046
Serine/threonine-protein kinase mTORHomo sapiens (human)Kd10.000012
Serine/threonine-protein kinase N1Homo sapiens (human)Kd8.688346
Serine/threonine-protein kinase N2Homo sapiens (human)Kd8.983346
Serine/threonine-protein kinase N3Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase Nek1Homo sapiens (human)Kd13.333346
Serine/threonine-protein kinase Nek11Homo sapiens (human)Kd10.000012
Serine/threonine-protein kinase Nek2Homo sapiens (human)Kd6.900068
Serine/threonine-protein kinase Nek3Homo sapiens (human)Kd16.666723
Serine/threonine-protein kinase Nek4Homo sapiens (human)Kd10.000012
Serine/threonine-protein kinase Nek5Homo sapiens (human)Kd10.000035
Serine/threonine-protein kinase Nek6Homo sapiens (human)Kd10.000035
Serine/threonine-protein kinase Nek7Homo sapiens (human)Kd10.383346
Serine/threonine-protein kinase Nek9Homo sapiens (human)Kd13.333346
Serine/threonine-protein kinase NIM1Homo sapiens (human)Kd3.900023
Serine/threonine-protein kinase NLKHomo sapiens (human)Kd10.333346
Serine/threonine-protein kinase OSR1Homo sapiens (human)Kd3.686723
Serine/threonine-protein kinase PAK 1Homo sapiens (human)Kd10.000035
Serine/threonine-protein kinase PAK 2Homo sapiens (human)Kd13.333346
Serine/threonine-protein kinase PAK 3Homo sapiens (human)Kd4.009635
Serine/threonine-protein kinase PAK 4Homo sapiens (human)Kd9.483346
Serine/threonine-protein kinase PAK 5Homo sapiens (human)Kd4.384035
Serine/threonine-protein kinase PAK 6Homo sapiens (human)Kd5.440035
Serine/threonine-protein kinase pim-1Homo sapiens (human)Kd13.333346
Serine/threonine-protein kinase pim-2Homo sapiens (human)Kd9.166746
Serine/threonine-protein kinase pim-3Homo sapiens (human)Kd5.440035
Serine/threonine-protein kinase PknBMycobacterium tuberculosis H37RvKd5.043512
Serine/threonine-protein kinase PLK1Homo sapiens (human)Kd13.333346
Serine/threonine-protein kinase PLK2Homo sapiens (human)Kd6.466723
Serine/threonine-protein kinase PLK3Homo sapiens (human)Kd10.000035
Serine/threonine-protein kinase PLK4Homo sapiens (human)Kd6.416368
Serine/threonine-protein kinase PRP4 homologHomo sapiens (human)Kd3.593323
Serine/threonine-protein kinase receptor R3Homo sapiens (human)Kd10.000035
Serine/threonine-protein kinase RIO1Homo sapiens (human)Kd4.021035
Serine/threonine-protein kinase RIO2Homo sapiens (human)Kd2.574534
Serine/threonine-protein kinase RIO3Homo sapiens (human)Kd6.280035
Serine/threonine-protein kinase SBK1Homo sapiens (human)Kd5.100012
Serine/threonine-protein kinase Sgk3Homo sapiens (human)Kd5.110012
Serine/threonine-protein kinase SIK1Homo sapiens (human)Kd5.920035
Serine/threonine-protein kinase SIK2Homo sapiens (human)Kd8.623346
Serine/threonine-protein kinase SIK3Homo sapiens (human)Kd15.000034
Serine/threonine-protein kinase STK11Homo sapiens (human)Kd8.352346
Serine/threonine-protein kinase TAO1Homo sapiens (human)Kd10.356045
Serine/threonine-protein kinase TAO2Homo sapiens (human)Kd16.666723
Serine/threonine-protein kinase TAO3Homo sapiens (human)Kd10.105034
Serine/threonine-protein kinase TBK1Homo sapiens (human)Kd2.935534
Serine/threonine-protein kinase TNNI3KHomo sapiens (human)Kd10.000035
Serine/threonine-protein kinase tousled-like 1Homo sapiens (human)Kd4.444035
Serine/threonine-protein kinase tousled-like 2Homo sapiens (human)Kd4.198035
Serine/threonine-protein kinase ULK1Homo sapiens (human)Kd3.054034
Serine/threonine-protein kinase ULK2Homo sapiens (human)Kd3.342023
Serine/threonine-protein kinase ULK3Homo sapiens (human)Kd2.802234
Serine/threonine-protein kinase ULK3Mus musculus (house mouse)Kd0.110011
Serine/threonine-protein kinase VRK2Homo sapiens (human)Kd10.000012
Serine/threonine-protein kinase/endoribonuclease IRE1Homo sapiens (human)Kd10.300034
Serine/threonine-protein kinase/endoribonuclease IRE2Homo sapiens (human)Kd30.000011
Signal recognition particle receptor subunit alphaHomo sapiens (human)Kd30.000011
SNF-related serine/threonine-protein kinaseHomo sapiens (human)Kd5.320012
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)EC501.450011
Sodium-dependent noradrenaline transporter Homo sapiens (human)EC5031.000011
Sodium/bile acid cotransporterHomo sapiens (human)Kd64.300011
Spike glycoproteinBetacoronavirus England 1EC5010.600011
Spike glycoproteinSevere acute respiratory syndrome-related coronavirusEC5010.600011
SRSF protein kinase 1Homo sapiens (human)Kd4.150035
SRSF protein kinase 2Homo sapiens (human)Kd4.114035
SRSF protein kinase 3Homo sapiens (human)Kd3.372723
STE20-like serine/threonine-protein kinase Homo sapiens (human)Kd0.433369
STE20-related kinase adapter protein alphaHomo sapiens (human)Kd30.000011
STE20/SPS1-related proline-alanine-rich protein kinaseHomo sapiens (human)Kd3.426723
Stimulator of interferon genes proteinHomo sapiens (human)EC5040.028366
Stimulator of interferon genes proteinHomo sapiens (human)Kd2.207544
Stimulator of interferon genes proteinMus musculus (house mouse)Kd0.110011
Stromelysin-1Homo sapiens (human)Kd25,000.000011
Structural maintenance of chromosomes protein 1AHomo sapiens (human)Kd30.000011
Structural maintenance of chromosomes protein 2Homo sapiens (human)Kd30.000011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrialHomo sapiens (human)Kd30.000011
Testis-specific serine/threonine-protein kinase 1Homo sapiens (human)Kd7.780035
TGF-beta receptor type-1Homo sapiens (human)Kd13.333346
TGF-beta receptor type-2Homo sapiens (human)Kd13.333346
Thyroid hormone receptor-associated protein 3Homo sapiens (human)Kd30.000011
TRAF2 and NCK-interacting protein kinaseHomo sapiens (human)Kd0.089169
Transient receptor potential cation channel subfamily A member 1Homo sapiens (human)EC50152,369.000023
Transient receptor potential cation channel subfamily A member 1Mus musculus (house mouse)EC5010.000011
Transient receptor potential cation channel subfamily M member 6Homo sapiens (human)Kd10.000012
Transmembrane prolyl 4-hydroxylaseHomo sapiens (human)EC5050.000011
Transmembrane protease serine 2Homo sapiens (human)EC5010.600011
TransporterRattus norvegicus (Norway rat)EC5051.000011
TransthyretinHomo sapiens (human)EC508.600011
TransthyretinHomo sapiens (human)Kd0.070011
Tubulin alpha-1A chainRattus norvegicus (Norway rat)Kd10.000012
Tumor necrosis factorHomo sapiens (human)EC500.018011
Tyrosine--tRNA ligase, cytoplasmicHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase ABL1Homo sapiens (human)EC501.000011
Tyrosine-protein kinase ABL1Homo sapiens (human)Kd3.16634090
Tyrosine-protein kinase ABL2Homo sapiens (human)Kd6.500057
Tyrosine-protein kinase BlkHomo sapiens (human)Kd0.311035
Tyrosine-protein kinase BTKHomo sapiens (human)Kd12.016746
Tyrosine-protein kinase CSKHomo sapiens (human)Kd13.333346
Tyrosine-protein kinase FerHomo sapiens (human)Kd3.814157
Tyrosine-protein kinase Fes/FpsHomo sapiens (human)Kd8.813346
Tyrosine-protein kinase FgrHomo sapiens (human)Kd2.863568
Tyrosine-protein kinase FRKHomo sapiens (human)Kd4.338868
Tyrosine-protein kinase FynHomo sapiens (human)Kd7.922957
Tyrosine-protein kinase HCKHomo sapiens (human)Kd3.983357
Tyrosine-protein kinase ITK/TSKHomo sapiens (human)Kd4.007835
Tyrosine-protein kinase JAK1Homo sapiens (human)Kd3.8764811
Tyrosine-protein kinase JAK2Homo sapiens (human)Kd7.452957
Tyrosine-protein kinase JAK3Homo sapiens (human)Kd4.720035
Tyrosine-protein kinase LckHomo sapiens (human)Kd0.856858
Tyrosine-protein kinase LynHomo sapiens (human)Kd1.088268
Tyrosine-protein kinase MerHomo sapiens (human)Kd1.495635
Tyrosine-protein kinase receptor Tie-1Homo sapiens (human)Kd4.783335
Tyrosine-protein kinase receptor TYRO3Homo sapiens (human)Kd4.029435
Tyrosine-protein kinase receptor UFOHomo sapiens (human)Kd4.005435
Tyrosine-protein kinase SrmsHomo sapiens (human)Kd10.000035
Tyrosine-protein kinase SYKHomo sapiens (human)EC504.500011
Tyrosine-protein kinase SYKHomo sapiens (human)Kd13.333346
Tyrosine-protein kinase TecHomo sapiens (human)Kd13.333346
Tyrosine-protein kinase TXKHomo sapiens (human)Kd10.000035
Tyrosine-protein kinase YesHomo sapiens (human)Kd1.594057
Tyrosine-protein kinase ZAP-70Homo sapiens (human)Kd10.000035
U5 small nuclear ribonucleoprotein 200 kDa helicaseHomo sapiens (human)Kd30.000011
UMP-CMP kinase Homo sapiens (human)Kd30.000011
Uncharacterized aarF domain-containing protein kinase 5Homo sapiens (human)Kd30.000011
Uncharacterized protein FLJ45252Homo sapiens (human)Kd0.431011
Uncharacterized serine/threonine-protein kinase SBK3Homo sapiens (human)Kd4.600023
Vascular endothelial growth factor receptor 1 Homo sapiens (human)Kd0.165135
Vascular endothelial growth factor receptor 2Homo sapiens (human)Kd1.226169
Vascular endothelial growth factor receptor 3Homo sapiens (human)Kd2.115058
Very long-chain specific acyl-CoA dehydrogenase, mitochondrialHomo sapiens (human)Kd30.000011
Vitamin D-binding proteinHomo sapiens (human)Kd0.024011
Vitamin D3 receptorBos taurus (cattle)EC500.000122
Vitamin D3 receptorHomo sapiens (human)EC500.03943636
Vitamin D3 receptorMus musculus (house mouse)EC500.100011
Vitamin D3 receptorRattus norvegicus (Norway rat)EC500.000277
Vitamin D3 receptorHomo sapiens (human)Kd0.000111
Vitamin D3 receptorSus scrofa (pig)Kd0.000111
Vitamin D3 receptor ADanio rerio (zebrafish)EC500.005511
Vitamin D3 receptor ADanio rerio (zebrafish)Kd1.200011
Wee1-like protein kinaseHomo sapiens (human)Kd8.883346
Wee1-like protein kinase 2Homo sapiens (human)Kd10.000023
Zinc finger protein AiolosHomo sapiens (human)EC500.054512
Zinc finger protein mex-5Caenorhabditis elegansEC5031.000011

Other Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
Adenosine receptor A1Homo sapiens (human)Affinity constant10.000011
Adenosine receptor A1Rattus norvegicus (Norway rat)Kb8.700011
Adenosine receptor A1Homo sapiens (human)KD hydro2,500.000011
Adenosine receptor A2aHomo sapiens (human)Affinity constant10.000011
Adenosine receptor A2aRattus norvegicus (Norway rat)Kb13.700011
Adenosine receptor A2aRattus norvegicus (Norway rat)Ratio25.000012
Adenosine receptor A2bHomo sapiens (human)Affinity constant10.000011
Adenosine receptor A2bMus musculus (house mouse)Kb16.000011
Adenosine receptor A2bRattus norvegicus (Norway rat)Ratio25.000012
Adenylate cyclase type 1Homo sapiens (human)Kb14.000011
Amyloid-beta precursor proteinHomo sapiens (human)DC500.755022
Androgen receptorHomo sapiens (human)EC15018.000011
Breakpoint cluster region proteinHomo sapiens (human)DC5010.000012
Carbonic anhydrase 1Homo sapiens (human)Kinact284.000011
Carbonic anhydrase 2Homo sapiens (human)Kinact17.750022
Carbonic anhydrase 5A, mitochondrialHomo sapiens (human)Kinact0.103011
Carbonic anhydrase 5B, mitochondrialHomo sapiens (human)Kinact0.098011
Carbonic anhydrase 9Homo sapiens (human)Kinact23.000011
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7Homo sapiens (human)AC5029.270011
Cytochrome P450 1A2Homo sapiens (human)ED500.000211
Cytochrome P450 2C9 Homo sapiens (human)ED500.000212
Cytochrome P450 3A4Homo sapiens (human)ED500.000211
DNA-binding protein IkarosHomo sapiens (human)DC500.058412
DNA-binding protein IkarosHomo sapiens (human)fEC500.280512
E3 ubiquitin-protein ligase ZFP91Homo sapiens (human)DC500.420011
EWS/FLI fusion proteinHomo sapiens (human)AbsAC35_uM40.250011
Glucocorticoid receptorHomo sapiens (human)EC15018.000011
Microtubule-associated protein tauHomo sapiens (human)DC50200.000011
Neuronal acetylcholine receptor subunit alpha-10Rattus norvegicus (Norway rat)K app0.006213
Neuronal acetylcholine receptor subunit alpha-2Rattus norvegicus (Norway rat)K app0.006213
Neuronal acetylcholine receptor subunit alpha-3Rattus norvegicus (Norway rat)K app0.006213
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)K app0.006213
Neuronal acetylcholine receptor subunit alpha-5Rattus norvegicus (Norway rat)K app0.006213
Neuronal acetylcholine receptor subunit alpha-6Rattus norvegicus (Norway rat)K app0.006213
Neuronal acetylcholine receptor subunit alpha-7Rattus norvegicus (Norway rat)K app0.006213
Neuronal acetylcholine receptor subunit alpha-9Rattus norvegicus (Norway rat)K app0.006213
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)K app0.006213
Neuronal acetylcholine receptor subunit beta-3Rattus norvegicus (Norway rat)K app0.006213
Neuronal acetylcholine receptor subunit beta-4Rattus norvegicus (Norway rat)K app0.006213
Pancreatic triacylglycerol lipaseSus scrofa (pig)ED5010.000011
Protein cereblonHomo sapiens (human)DC505.029224
Protein cereblonHomo sapiens (human)fEC500.280512
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)INH0.056622
Retinoic acid receptor RXR-alphaHomo sapiens (human)ED504.900011
Seed linoleate 13S-lipoxygenase-1Glycine max (soybean)Km169.050022
Seed linoleate 13S-lipoxygenase-1Glycine max (soybean)Vmax0.010522
Solute carrier family 22 member 1 Homo sapiens (human)Activity53.200011
TransporterRattus norvegicus (Norway rat)K app0.006211
Tyrosine-protein kinase ABL1Homo sapiens (human)DC5010.000012
UDP-glucuronosyltransferase 1A1 Homo sapiens (human)Km28.750022
UDP-glucuronosyltransferase 1A10Homo sapiens (human)Km10.300011
UDP-glucuronosyltransferase 1A7Homo sapiens (human)Km9.400011
UDP-glucuronosyltransferase 1A8Homo sapiens (human)Km79.200022
UDP-glucuronosyltransferase 1A9Homo sapiens (human)Km5.000011
Vasopressin V2 receptorSus scrofa (pig)Kb14.000011
Vitamin D3 receptorHomo sapiens (human)ED500.100744
Vitamin D3 receptorRattus norvegicus (Norway rat)ED50500,000.000266
Xanthine dehydrogenase/oxidaseBos taurus (cattle)Km32.350044