Page last updated: 2024-09-28

Stye

Synonyms(1)

Synonym
Stye

Research

Studies (40)

TimeframeStudies, This Condition (%)All Conditions %
pre-199030 (75.00)23.3326
1990's2 (5.00)12.5806
2000's5 (12.50)18.1394
2010's1 (2.50)28.8240
2020's2 (5.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
urea0low10
phenytoin0low10
acetazolamide0low10
gentamicin0low30
lidocaine0low10
ofloxacin0medium21
oxyphenbutazone0low10
propofol0low10
sulfadimethoxine0low10
sulfanilamide0low10
sulfaphenazole0low10
sulfisoxazole0low10
methylprednisolone acetate0low10
pilocarpine0low10
chloramphenicol0low10
kanamycin a0low50
methylprednisolone0low10
framycetin0medium31
erythromycin0low10
streptomycin0low20
hypochlorous acid0low10
triamcinolone0low10
propiconazole0low20
clindamycin0low60
zithromax0low10
glycosides0low10
gramicidin a0medium11
colistin0low10
tetracycline0low30
alcian blue0low10
eye0low80

Protein Targets (518)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, TYROSYL-DNA PHOSPHODIESTERASE5005
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Beta-lactamase5005
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Class Iii Chitinase Chia10101
Chain A, Carbonic anhydrase 130101
Chain A, Carbonic anhydrase II0101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase0101
Chain B, Carbonic anhydrase0101
Chain A, Carbonic anhydrase 20101
Carbonic anhydrase 0002
Carbonic anhydrase 0202
thioredoxin reductase9009
GALC protein1001
GLI family zinc finger 3140014
nuclear receptor subfamily 1, group I, member 37007
cytochrome P450 family 3 subfamily A polypeptide 46006
glucocorticoid receptor [Homo sapiens]8008
retinoic acid nuclear receptor alpha variant 1110011
retinoid X nuclear receptor alpha8008
estrogen-related nuclear receptor alpha150015
Carbonic anhydrase 0202
Carbonic anhydrase 0202
arylsulfatase A6006
Carbonic anhydrase0202
euchromatic histone-lysine N-methyltransferase 2100010
Bloom syndrome protein isoform 14004
thyroid hormone receptor beta isoform a4004
nuclear factor erythroid 2-related factor 2 isoform 1100010
geminin120012
peripheral myelin protein 221001
survival motor neuron protein isoform d1001
muscleblind-like protein 1 isoform 13003
Gamma-aminobutyric acid receptor subunit pi84113
ATP-binding cassette sub-family C member 3010010
Multidrug resistance-associated protein 4010010
Carbonic anhydrase0202
Solute carrier family 22 member 60202
Carbonic anhydrase 120316
Prolyl endopeptidase0101
Carbonic anhydrase-related protein 110102
Bile salt export pump013013
Glycogen phosphorylase, muscle form0101
Renin0202
Carbonic anhydrase 105111
Carbonic anhydrase 205211
Carbonic anhydrase 20314
Cytochrome P450 1A20101
Carbonic anhydrase 30316
Cathepsin B0101
Cytochrome P450 3A40505
Steryl-sulfatase0101
5-hydroxytryptamine receptor 2C0202
Polyunsaturated fatty acid 5-lipoxygenase0101
Cytochrome P450 2C80202
Cytochrome P450 2D60101
Cytochrome P450 2A60213
Cytochrome P450 2C9 0606
5-hydroxytryptamine receptor 2A0202
Androgen receptor0303
Gamma-aminobutyric acid receptor subunit beta-184113
Translocator protein0101
Gamma-aminobutyric acid receptor subunit delta84113
Gamma-aminobutyric acid receptor subunit gamma-284113
Gamma-aminobutyric acid receptor subunit alpha-584113
Gamma-aminobutyric acid receptor subunit alpha-384113
Cannabinoid receptor 10101
Arachidonate 5-lipoxygenase-activating protein0101
Cytochrome P450 2B60101
Carbonic anhydrase 40315
Carbonic anhydrase 60416
Gamma-aminobutyric acid receptor subunit gamma-184113
Gamma-aminobutyric acid receptor subunit alpha-284113
Carbonic anhydrase 5A, mitochondrial0202
Adenosine receptor A10101
Serum paraoxonase/arylesterase 10101
Dipeptidyl peptidase 40001
Gamma-aminobutyric acid receptor subunit alpha-484113
Gamma-aminobutyric acid receptor subunit gamma-384113
Endochitinase0101
Gamma-aminobutyric acid receptor subunit alpha-684113
Adenosine receptor A2a0101
5-hydroxytryptamine receptor 2B0202
Sodium-dependent serotonin transporter0101
Delta-type opioid receptor0202
Cytochrome P450 2C190202
Delta-type opioid receptor0202
Mu-type opioid receptor0202
Carbonic anhydrase 5A, mitochondrial0418
Carbonic anhydrase0202
Kappa-type opioid receptor0101
Carbonic anhydrase 70315
Carbonic anhydrase0101
D(1A) dopamine receptor0101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Carbonic anhydrase0202
D(2) dopamine receptor0101
Gamma-aminobutyric acid receptor subunit alpha-184113
Gamma-aminobutyric acid receptor subunit beta-384113
Gamma-aminobutyric acid receptor subunit beta-284113
Cholinesterase0101
Carbonic anhydrase 0202
Mu-type opioid receptor0202
Fatty-acid amide hydrolase 10202
Beta-carbonic anhydrase 10202
Carbonic anhydrase 20202
Glutamate receptor ionotropic, NMDA 2B0101
Squalene synthase0101
Neuronal acetylcholine receptor subunit alpha-70101
Carbonic anhydrase 90417
Carbonic anhydrase0101
Carbonic anhydrase, alpha family 0202
Carbonic anhydrase 0202
Carbonic anhydrase 30101
Carbonic anhydrase0203
Carbonic anhydrase0203
Carbonic anhydrase 0202
Sigma intracellular receptor 20101
Delta carbonic anhydrase0202
Sigma non-opioid intracellular receptor 10101
Renin0101
Carbonic anhydrase 0202
Endochitinase A10101
Multidrug resistance-associated protein 10101
Carbonic anhydrase 130315
GABA theta subunit84113
Canalicular multispecific organic anion transporter 10909
Carbonic anhydrase 40303
Carbonic anhydrase 150203
Acidic mammalian chitinase0101
Carbonic anhydrase 130304
Carbonic anhydrase 70101
Gamma-aminobutyric acid receptor subunit epsilon84113
Carbonic anhydrase 0101
Carbonic anhydrase 140316
Carbonic anhydrase 0101
Carbonic anhydrase 2, isoform A 0101
Carbonic anhydrase 5B, mitochondrial0317
interleukin 83003
TDP1 protein120012
AR protein120012
aldehyde dehydrogenase 1 family, member A19009
EWS/FLI fusion protein4004
farnesoid X nuclear receptor5005
pregnane X nuclear receptor110011
estrogen nuclear receptor alpha150015
G6006
cytochrome P450 2D62002
peroxisome proliferator activated receptor gamma4004
vitamin D (1,25- dihydroxyvitamin D3) receptor5005
aryl hydrocarbon receptor2002
activating transcription factor 62002
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a2002
thyroid hormone receptor beta isoform 29009
heat shock protein beta-14004
DNA polymerase iota isoform a (long)6006
streptokinase A precursor0044
lethal factor (plasmid)3003
Dihydroxyacetone phosphate acyltransferase0002
Interferon beta8008
HLA class I histocompatibility antigen, B alpha chain 6006
30S ribosomal protein S60516
30S ribosomal protein S70516
50S ribosomal protein L150516
Cellular tumor antigen p537007
50S ribosomal protein L100516
50S ribosomal protein L110516
50S ribosomal protein L7/L120516
50S ribosomal protein L190516
50S ribosomal protein L10516
50S ribosomal protein L200516
50S ribosomal protein L270516
50S ribosomal protein L280516
50S ribosomal protein L290516
50S ribosomal protein L310516
50S ribosomal protein L31 type B0516
50S ribosomal protein L320516
50S ribosomal protein L330516
50S ribosomal protein L340516
50S ribosomal protein L350516
50S ribosomal protein L360516
30S ribosomal protein S100516
30S ribosomal protein S110516
30S ribosomal protein S120516
30S ribosomal protein S130516
30S ribosomal protein S160516
30S ribosomal protein S180516
30S ribosomal protein S190516
30S ribosomal protein S200516
30S ribosomal protein S20516
30S ribosomal protein S30516
30S ribosomal protein S40516
30S ribosomal protein S50516
30S ribosomal protein S80516
30S ribosomal protein S90516
50S ribosomal protein L130516
50S ribosomal protein L140516
50S ribosomal protein L160516
50S ribosomal protein L230516
30S ribosomal protein S150516
50S ribosomal protein L170516
50S ribosomal protein L210516
50S ribosomal protein L300516
50S ribosomal protein L60516
30S ribosomal protein S140516
30S ribosomal protein S170516
30S ribosomal protein S10516
50S ribosomal protein L180516
50S ribosomal protein L20516
50S ribosomal protein L30516
50S ribosomal protein L240516
50S ribosomal protein L40516
50S ribosomal protein L220516
50S ribosomal protein L50516
30S ribosomal protein S210516
50S ribosomal protein L250516
50S ribosomal protein L36 20516
Inositol hexakisphosphate kinase 16006
Methionine--tRNA ligase, mitochondrial0011
cytochrome P450 2C9, partial6006
Protein-arginine deiminase type-40505
Motilin receptor0011
acid sphingomyelinase1001
low molecular weight phosphotyrosine protein phosphatase isoform c0101
serine/threonine-protein kinase PLK12002
Motilin receptor0112
Rap guanine nucleotide exchange factor 33003
Albumin0022
ATP-dependent translocase ABCB10202
ATP-dependent translocase ABCB10202
60 kDa chaperonin0101
60 kDa heat shock protein, mitochondrial0101
Chitinase B0101
ATP-dependent translocase ABCB10202
Low molecular weight phosphotyrosine protein phosphatase0101
Cytochrome P450 2J20303
10 kDa heat shock protein, mitochondrial0101
Potassium voltage-gated channel subfamily H member 20404
Cytochrome P450 1B10101
Thiosulfate sulfurtransferase0101
Lanosterol 14-alpha demethylase0202
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Multidrug and toxin extrusion protein 10202
Menin0011
Lecithin retinol acyltransferase0101
Lethal factor0101
Protein Rev 0011
Aminoglycoside 3'-phosphotransferase 0001
Tyrosyl-DNA phosphodiesterase 10101
3-oxoacyl-[acyl-carrier-protein] synthase 30101
Gap junction alpha-1 protein0101
Gap junction beta-2 protein0101
Spike glycoprotein3003
Acyl-protein thioesterase 10101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE5005
RAR-related orphan receptor gamma5005
GLS protein4004
Microtubule-associated protein tau3003
IDH15005
chromobox protein homolog 1100010
mitogen-activated protein kinase 11001
flap endonuclease 13003
cytochrome P450 3A4 isoform 18008
muscarinic acetylcholine receptor M14004
lamin isoform A-delta109009
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0202
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50101
Sodium channel protein type 4 subunit alpha0203
Sodium channel protein type 5 subunit alpha0202
Sodium channel protein type 9 subunit alpha0202
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Sodium channel protein type 3 subunit alpha0202
acetylcholinesterase1001
hypoxia-inducible factor 1 alpha subunit1001
PPM1D protein2002
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
progesterone receptor7007
nonstructural protein 12002
bromodomain adjacent to zinc finger domain 2B1001
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a8008
nuclear receptor subfamily 1, group I, member 23003
nuclear factor erythroid 2-related factor 2 isoform 27007
Nuclear receptor subfamily 1 group I member 20011
Glucocorticoid receptor0617
Glycine receptor subunit alpha-10606
Glycine receptor subunit beta0606
Glycine receptor subunit alpha-20606
Glycine receptor subunit alpha-30606
ATPase family AAA domain-containing protein 53003
Ataxin-23003
Nuclear receptor subfamily 1 group I member 20011
ATP-dependent phosphofructokinase2002
USP1 protein, partial5005
importin subunit beta-1 isoform 11001
snurportin-11001
GTP-binding nuclear protein Ran isoform 11001
urokinase-type plasminogen activator precursor2002
plasminogen precursor2002
urokinase plasminogen activator surface receptor precursor2002
Glucose-6-phosphate 1-dehydrogenase0101
Chain A, HADH2 protein4004
Chain B, HADH2 protein4004
Chain A, 2-oxoglutarate Oxygenase1001
Chain A, Ferritin light chain4004
STE240001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 13003
parathyroid hormone/parathyroid hormone-related peptide receptor precursor3003
CAAX prenyl protease0001
histone acetyltransferase KAT2A isoform 11001
Trypsin0001
DNA gyrase subunit A0102
DNA gyrase subunit B0102
DNA gyrase subunit B0102
DNA gyrase subunit A0102
Chain A, JmjC domain-containing histone demethylation protein 3A1001
Luciferase1001
Nrf21001
glp-1 receptor, partial6006
SMAD family member 23003
ATAD5 protein, partial2002
Fumarate hydratase1001
SMAD family member 33003
Microphthalmia-associated transcription factor0001
thioredoxin glutathione reductase3003
Smad33003
estrogen receptor 2 (ER beta)4004
hypothetical protein, conserved1001
polyprotein1001
peroxisome proliferator-activated receptor delta4004
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0101
caspase recruitment domain family, member 150101
v-jun sarcoma virus 17 oncogene homolog (avian)4004
Caspase-71001
cellular tumor antigen p53 isoform a1001
vitamin D3 receptor isoform VDRA4004
glucose-6-phosphate 1-dehydrogenase isoform b0101
caspase-31001
histone deacetylase 9 isoform 31001
receptor-interacting serine/threonine-protein kinase 2 isoform 10101
ras-related protein Rab-9A1001
nuclear receptor ROR-gamma isoform 14004
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
Guanine nucleotide-binding protein G2002
TAR DNA-binding protein 433003
Nicotinate phosphoribosyltransferase0101
Beta lactamase (plasmid)0101
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
Gamma-aminobutyric acid 0101
endonuclease IV1001
regulator of G-protein signaling 42002
peripheral myelin protein 22 isoform 12002
cytochrome P450 2C9 precursor4004
atrial natriuretic peptide receptor 1 precursor1001
transcriptional regulator ERG isoform 33003
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Dihydrofolate reductase 0101
Gamma-aminobutyric acid receptor subunit alpha-10213
Aldo-keto reductase family 1 member B10101
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit beta-10112
Gamma-aminobutyric acid receptor subunit gamma-20213
5-hydroxytryptamine receptor 1A0101
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit beta-30213
Gamma-aminobutyric acid receptor subunit alpha-50112
Gamma-aminobutyric acid receptor subunit alpha-30112
Sodium channel protein type 1 subunit alpha0101
Histamine H2 receptor6006
Gamma-aminobutyric acid receptor subunit alpha-20112
Gamma-aminobutyric acid receptor subunit beta-20112
Gamma-aminobutyric acid receptor subunit alpha-40112
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit epsilon0101
Inositol monophosphatase 11001
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Gamma-aminobutyric acid receptor subunit alpha-60112
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit pi0101
Sodium channel protein type 2 subunit alpha0101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit theta0101
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit theta0101
cytochrome P450 2C19 precursor3003
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
Muscarinic acetylcholine receptor M20213
Muscarinic acetylcholine receptor M10203
Muscarinic acetylcholine receptor M30203
Muscarinic acetylcholine receptor M40203
Muscarinic acetylcholine receptor M50203
Muscarinic acetylcholine receptor M50101
Muscarinic acetylcholine receptor M20203
Muscarinic acetylcholine receptor M10123
Muscarinic acetylcholine receptor M10011
Muscarinic acetylcholine receptor DM10101
Cytochrome P450 2A130112
pregnane X receptor2002
Nuclear receptor ROR-gamma2002
phosphopantetheinyl transferase1001
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
heat shock protein HSP 90-alpha isoform 20102
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
Voltage-dependent calcium channel gamma-2 subunit2002
Glutamate receptor 22002
heat shock protein 90, putative0001
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
caspase 7, apoptosis-related cysteine protease2002
thyroid stimulating hormone receptor5005
caspase-32002
Histone H2A.x3003
D(1A) dopamine receptor1001
Fatty-acid amide hydrolase 10101
UDP-glucuronosyltransferase 1A90001
5-hydroxytryptamine receptor 40202
Aldo-keto reductase family 1 member B10202
Gamma-aminobutyric acid receptor subunit alpha-10001
Gamma-aminobutyric acid receptor subunit beta-10001
Gamma-aminobutyric acid receptor subunit alpha-20001
Gamma-aminobutyric acid receptor subunit alpha-30001
Polyunsaturated fatty acid lipoxygenase ALOX150101
Gamma-aminobutyric acid receptor subunit alpha-40001
Gamma-aminobutyric acid receptor subunit gamma-20001
Prostaglandin G/H synthase 10101
Sodium-dependent noradrenaline transporter 0202
Sodium- and chloride-dependent GABA transporter 10101
5-hydroxytryptamine receptor 2C0202
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
5-hydroxytryptamine receptor 2B0202
Sodium- and chloride-dependent betaine transporter0101
UDP-glucuronosyltransferase 1A80001
Bile salt export pump0101
Enoyl-[acyl-carrier-protein] reductase [NADH]0001
Chain A, Cruzipain1001
5-hydroxytryptamine receptor 60202
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
Cholinesterase0101
Acetylcholinesterase0101
Disintegrin and metalloproteinase domain-containing protein 171001
Protein argonaute-20011
NFKB1 protein, partial2002
Thrombopoietin1001
DNA polymerase beta1001
neuropeptide S receptor isoform A1001
UDP-glucuronosyltransferase 2B70101
UDP-glucuronosyltransferase 1-60101
UDP-glucuronosyltransferase 1A1 0101
UDP-glucuronosyltransferase 1A40101
Cytochrome P450 2C180101
UDP-glucuronosyltransferase 2B10 0101
67.9K protein1001
Endothelin-1 receptor0202
Endothelin-1 receptor0101
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Tetracycline resistance protein, class B0001
72 kDa type IV collagenase0101
Stromelysin-10101
Multidrug transporter MdfA0101
Alpha-1B adrenergic receptor0101
Neutrophil collagenase0101
Alpha-1D adrenergic receptor0101
Alpha-synuclein0101
Alpha-1A adrenergic receptor0101
Collagenase 30101
Cannabinoid receptor 10101
Integrase 0101
Solute carrier family 22 member 80001
P2Y purinoceptor 120101
Solute carrier family 22 member 110001
Solute carrier family 22 member 70001
procathepsin L isoform 1 preproprotein0101
Urease subunit alpha0101
Urease subunit beta0101
Olfactory receptor 51E20011
thyroid stimulating hormone receptor1001
twin arginine protein translocation system - TatA protein0001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]