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xanthones
Any member of the class of xanthenes based on a xanthone skeleton.
ChEBI ID: 51149
Members (37)
| Member | Definition | Role |
|---|---|---|
| 1,2,8-trihydroxy-6-methoxyxanthone | A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 2 and 8 and a methoxy group at position 6. It has been isolated from various species of the genus Swertia and has been found to exhibit antioxidant activities. | swertianin |
| 1,7-dihydroxy-4-methoxyxanthone | A member of the class of xanthones that is 9H-xanthene substituted by hydroxy groups at positions 1 and 7, a methoxy group at position 4 and an oxo group at position 9. It has been isolated from the stems of Cratoxylum cochinchinense. | 1,7-dihydroxy-4-methoxyxanthone |
| 1,8-dihydroxy-3,7-dimethoxyxanthone | A member of the class of xanthones that is swertianin in which the hydroxy group at position 2 has been replaced by a methoxy group. | 2-O-methylswertianin |
| 2-[3-(4-morpholinyl)propylamino]-9-xanthenone | 2-[3-(4-morpholinyl)propylamino]-9-xanthenone | |
| 2-Methoxyxanthone | 2-Methoxyxanthone | |
| 2,3,6,8-tetrahydroxy-1-(3-methylbut-2-enyl)-5-(2-methylbut-3-en-2-yl)-9h-xanthen-9-one | A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 2, 3, 6 and 8, an isoprenyl group at position 1 and a 2-methylbut-3-en-2-yl group at position 5. It is isolated from the root barks of Cudrania tricuspidata and exhibits cytotoxicity towards human cancer cell lines. | cudratricusxanthone A |
| 3-isomangostin | 3-Isomangostin | |
| 8-deoxygartanin | 8-Desoxygartanin | |
| 9-Hydroxycalabaxanthone | 9-Hydroxycalabaxanthone | |
| ah 6809 | 9-oxo-6-propan-2-yloxy-2-xanthenecarboxylic acid | |
| bellidifolin | A member of the xanthone family that is bellidin substituted with a methyl group at O-3. A natural product found particularly in Swertia chirata and Gentianella campestris. | bellidifolin |
| beta-Mangostin | beta-Mangostin | |
| decussatin | A member of the class of xanthones that is xanthone substituted by a hydroxy group at position 1 and methoxy groups at positions 1, 2 and 6. It has been isolated from Centaurium erythraea and Gentiana verna. | decussatin |
| demethylbellidifolin | A member of the class of xanthones that is xanthone which is substituted by hydroxy groups at positions 1, 3, 5, and 8. A natural product found particularly in Iris nigricans and Gentiana campestris. | bellidin |
| euxanthone | A member of the class of xanthones that is 9H-xanthene substituted by hydroxy group at positions 1 and 7 and an oxo group at position 9. It has been isolated from Cratoxylum cochinchinense. | euxanthone |
| gamma-mangostin | A member of the class of xanthones that is 9H-xanthene substituted by hydroxy group at positions 1, 3, 6 and 7, an oxo group at position 9 and prenyl groups at positions 2 and 8. Isolated from the stems of Cratoxylum cochinchinense, it exhibits antitumour activity. | gamma-mangostin |
| garcinone c | Garcinone C | |
| garcinone e | Garcinone E | |
| gartanin | A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3, 5 and 8 and prenyl groups at positions 2 and 4. | gartanin |
| gentiacaulein | A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 2 and 8 and methoxy groups at positions 1 and 6. | gentiacaulein |
| gentisein | A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3 and 7. | gentisein |
| gentisin | A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1 and 7 and a methoxy group at position 3. | gentisin |
| isogentisin | A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1 and 3 and a methoxy group at position 7. | isogentisin |
| isomangiferin | A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3, 6 and 7 and a 1,5-anhydro-D-glucitol moiety at position 1. | isomangiferin |
| lichexanthone | A member of the class of xanthones that is 9H-xanthen-9-one substituted by a hydroxy group at position 1, a methyl group at position 8 and methoxy groups at positions 3 and 6. It has been isolated from the bark of Cupania cinerea. | lichexanthone |
| macluraxanthone b | A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3, 6 and 7, a dimethylallyl group at position 2 and a prenyl group at position 4. Isolated from Maclura tinctoria and Cudrania tricuspidata, it exhibits anti-HIV and antineoplastic activity. | macluraxanthone B |
| mangiferin | A C-glycosyl compound consisting of 1,3,6,7-tetrahydroxyxanthen-9-one having a beta-D-glucosyl residue at the 6-position. | mangiferin |
| mangostin | A member of the class of xanthones that is 9H-xanthene substituted by hydroxy group at positions 1, 3 and 6, a methoxy group at position 7, an oxo group at position 9 and prenyl groups at positions 2 and 8. Isolated from the stems of Cratoxylum cochinchinense, it exhibits antioxidant, antimicrobial and antitumour activities. | alpha-mangostin |
| nidulalin a | A member of the class xanthones which consists of a dihydroxanthone skeleton substituted by hydroxy groups at positions 4 and 8, a methyl group at position 6 and a methoxycarbonyl group at position 4a (the 4R,4aS stereoisomer). It is isolated from Emericella nidulans var lata and Penicillium and exhibits potent antitumour activity against both human and murine tumour cell lines. | nidulalin A |
| norathyriol | A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3, 6 and 7. Isolated from Garcinia mangostana and Maclura pomifera, it exhibits inhibitory activity against protein kinase C. | norathyriol |
| norlichexanthone | A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3 and 6 and a methyl group at position 8. It has been isolated from Wardomyces anomalus. | norlichexanthone |
| norswertianolin | A beta-D-glucoside that is bellidin in which a beta-D-glucopyranosyl residue is attached at position O-8. A natural product found particularly in Gentiana campestris and Gentiana germanica. | norswertianolin |
| psorospermin | An organic heterotetracyclic compound that is 1,2-dihydro-6H-furo[2,3-c]xanthene substituted by a hydroxy group at position 10, a methoxy group at position 5 nad a 2-methyloxiran-2-yl group at position 2. | psorospermin |
| rubraxanthone | A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 3, 6 and 8, a geranyl group at position 1 and a methoxy group at position 2. Isolated from Mesua and Garcinia dioica, it exhibits antibacterial and cytotoxic activities. | rubraxanthone |
| swerchirin | A member of the class of xanthones that is the 5-O-methyl derivative of bellidifolin. Isolated from Centaurium erythraea and Swertia chirayita, it exhibits hypoglycemic activity. | swerchirin |
| vadimezan | A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is replaced by a 5,6-dimethyl-9-oxoxanthen-4-yl group. | vadimezan |
| xanthone | The parent compound of the xanthone class consisting of xanthene bearing a single oxo substituent at position 9. | xanthone |
Research
Studies (1,884)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 22 (1.17) | 18.7374 |
| 1990's | 158 (8.39) | 18.2507 |
| 2000's | 483 (25.64) | 29.6817 |
| 2010's | 928 (49.26) | 24.3611 |
| 2020's | 293 (15.55) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 25 (1.15%) | 5.53% |
| Reviews | 119 (5.49%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 2,022 (93.35%) | 84.16% |