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amidoxime

Amidines of general formula RC(=NOH)NR(1)R(2), in which the imino nitrogen is substituted by a hydroxy group.

ChEBI ID: 65234

Members (2)

MemberDefinitionRole
benzamidoximeA member of the class of amidoximes obtained by formal condensation of the carbonyl group of benzamide with hydroxylamine.benzamidoxime
ximelagatranA member of the class of azetidines that is melagatran in which the carboxylic acid group has been converted to the corresponding ethyl ester and in which the amidine group has been converted into the corresponding amidoxime. A prodrug for melagatran, ximelagatran was the first orally available direct thrombin inhibitor to be brought to market as an anticoagulant, but was withdrawn in 2006 following reports of it causing liver damage.ximelagatran (hydroxylamine form); ximelagatran

Research

Studies (413)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19903 (0.73)18.7374
1990's6 (1.45)18.2507
2000's334 (80.87)29.6817
2010's67 (16.22)24.3611
2020's3 (0.73)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials75 (17.40%)5.53%
Reviews179 (41.53%)6.00%
Case Studies1 (0.23%)4.05%
Observational0 (0.00%)0.25%
Other176 (40.84%)84.16%