Page last updated: 2024-08-05 11:49:20

thiazoles

An azole in which the five-membered heterocyclic aromatic skeleton contains a N atom and one S atom.

ChEBI ID: 48901

Members (70)

MemberDefinitionRole
[[2-[(4,5-dimethyl-2-thiazolyl)amino]-2-oxoethyl]thio]methanethioic acid O-ethyl ester[[2-[(4,5-dimethyl-2-thiazolyl)amino]-2-oxoethyl]thio]methanethioic acid O-ethyl ester
1-[4-methyl-2-[2-(4-methylphenoxy)ethylamino]-5-thiazolyl]ethanone1-[4-methyl-2-[2-(4-methylphenoxy)ethylamino]-5-thiazolyl]ethanone
2-(2-Thienyl)-1,3-thiazole-4-carboxylic acid2-(2-Thienyl)-1,3-thiazole-4-carboxylic acid
2-(3-pyridinyl)-4-thiophen-2-ylthiazole2-(3-pyridinyl)-4-thiophen-2-ylthiazole
2-(4-chlorophenoxy)-N-(5-nitro-2-thiazolyl)acetamide2-(4-chlorophenoxy)-N-(5-nitro-2-thiazolyl)acetamide
2-[(4-chlorophenyl)-[2-[5-(4-chlorophenyl)-2-thiazolyl]-5-methyl-3-oxo-1H-pyrazol-4-yl]methyl]propanedinitrile2-[(4-chlorophenyl)-[2-[5-(4-chlorophenyl)-2-thiazolyl]-5-methyl-3-oxo-1H-pyrazol-4-yl]methyl]propanedinitrile
2-[(5-chloro-2-thiophenyl)-oxomethyl]imino-3,4-dimethyl-5-thiazolecarboxylic acid ethyl ester2-[(5-chloro-2-thiophenyl)-oxomethyl]imino-3,4-dimethyl-5-thiazolecarboxylic acid ethyl ester
2-[(5-methyl-4-phenyl-2-thiazolyl)methyl]-4-thiazolol2-[(5-methyl-4-phenyl-2-thiazolyl)methyl]-4-thiazolol
2-[[(5-ethyl-2-thiophenyl)-oxomethyl]amino]-4-methyl-5-thiazolecarboxylic acid ethyl ester2-[[(5-ethyl-2-thiophenyl)-oxomethyl]amino]-4-methyl-5-thiazolecarboxylic acid ethyl ester
2-[[2-[[4-hydroxy-6-oxo-5-(phenylmethyl)-1H-pyrimidin-2-yl]thio]-1-oxoethyl]amino]-4-methyl-5-thiazolecarboxylic acid ethyl ester2-[[2-[[4-hydroxy-6-oxo-5-(phenylmethyl)-1H-pyrimidin-2-yl]thio]-1-oxoethyl]amino]-4-methyl-5-thiazolecarboxylic acid ethyl ester
2-[[4-amino-2-(ethylamino)-5-thiazolyl]-phenylmethylidene]propanedinitrile2-[[4-amino-2-(ethylamino)-5-thiazolyl]-phenylmethylidene]propanedinitrile
2-[2-(3,5-dimethyl-1-pyrazolyl)ethyl]-4-thiophen-2-ylthiazole2-[2-(3,5-dimethyl-1-pyrazolyl)ethyl]-4-thiophen-2-ylthiazole
2-[2-(4-fluoroanilino)-4-thiophen-2-yl-5-thiazolyl]acetic acid2-[2-(4-fluoroanilino)-4-thiophen-2-yl-5-thiazolyl]acetic acid
2-[2-[5-amino-4-(3-thiophenyl)-1-pyrazolyl]-4-phenyl-5-thiazolyl]acetic acid2-[2-[5-amino-4-(3-thiophenyl)-1-pyrazolyl]-4-phenyl-5-thiazolyl]acetic acid
2-[4-(4-chlorophenyl)-2-thiazolyl]ethanethioamide2-[4-(4-chlorophenyl)-2-thiazolyl]ethanethioamide
2-[4-(4-fluorophenyl)-2-thiazolyl]-5-methyl-4H-pyrazol-3-one2-[4-(4-fluorophenyl)-2-thiazolyl]-5-methyl-4H-pyrazol-3-one
2-acetyl-2-thiazoline2-Acetyl-4,5-dihydrothiazole
2-amino-5-nitrothiazole2-Amino-5-nitrothiazole
2-methylthiazoline2-Methyl-4,5-dihydro-1,3-thiazole
2,4-Di(3-pyridyl)-1,3-thiazole2,4-Di(3-pyridyl)-1,3-thiazole
2,4-Dimethyl-1,3-thiazole-5-carboxylic acid2,4-Dimethyl-1,3-thiazole-5-carboxylic acid
2,4-dithiophen-2-ylthiazole2,4-dithiophen-2-ylthiazole
3-[2-(4-chlorophenyl)-4-thiazolyl]-4-ethyl-1H-1,2,4-triazole-5-thione3-[2-(4-chlorophenyl)-4-thiazolyl]-4-ethyl-1H-1,2,4-triazole-5-thione
3-[2-(cyclohexylamino)-4-(4-methoxyphenyl)-5-thiazolyl]propanoic acid methyl ester3-[2-(cyclohexylamino)-4-(4-methoxyphenyl)-5-thiazolyl]propanoic acid methyl ester
4-(1-adamantyl)-2-methyl-1,3-thiazole4-(1-adamantyl)-2-methyl-1,3-thiazole
4-(2,4-dimethyl-5-thiazolyl)-N-(phenylmethyl)-2-thiazolamine4-(2,4-dimethyl-5-thiazolyl)-N-(phenylmethyl)-2-thiazolamine
4-(3-chloro-2-thiophenyl)-2-(3-pyridinyl)thiazole4-(3-chloro-2-thiophenyl)-2-(3-pyridinyl)thiazole
4-(3-fluorophenyl)-2-thiazolamine4-(3-fluorophenyl)-2-thiazolamine
4-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-2-methylthiazole4-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-2-methylthiazole
4-(3,4-dimethylphenyl)-5-phenyl-2-thiazolamine4-(3,4-dimethylphenyl)-5-phenyl-2-thiazolamine
4-amino-3-(4-ethoxyphenyl)-N-(2-oxolanylmethyl)-2-sulfanylidene-5-thiazolecarboxamide4-amino-3-(4-ethoxyphenyl)-N-(2-oxolanylmethyl)-2-sulfanylidene-5-thiazolecarboxamide
4-amino-3-[(cyclohexylamino)-oxomethyl]-5-isothiazolecarboxylic acid [1-(cyclohexylamino)-1-oxopropan-2-yl] ester4-amino-3-[(cyclohexylamino)-oxomethyl]-5-isothiazolecarboxylic acid [1-(cyclohexylamino)-1-oxopropan-2-yl] ester
4-amino-3-[(cyclohexylamino)-oxomethyl]-5-isothiazolecarboxylic acid ethyl ester4-amino-3-[(cyclohexylamino)-oxomethyl]-5-isothiazolecarboxylic acid ethyl ester
4-amino-3-methyl-N-(phenylmethyl)-2-sulfanylidene-5-thiazolecarboxamide4-amino-3-methyl-N-(phenylmethyl)-2-sulfanylidene-5-thiazolecarboxamide
4-amino-3-phenyl-2-sulfanylidene-5-thiazolecarboxylic acid methyl ester4-amino-3-phenyl-2-sulfanylidene-5-thiazolecarboxylic acid methyl ester
4-amino-N-(2-oxolanylmethyl)-3-prop-2-enyl-2-sulfanylidene-5-thiazolecarboxamide4-amino-N-(2-oxolanylmethyl)-3-prop-2-enyl-2-sulfanylidene-5-thiazolecarboxamide
4-methyl-5-[2-[(phenylmethyl)amino]-4-thiazolyl]-2-thiazolamine4-methyl-5-[2-[(phenylmethyl)amino]-4-thiazolyl]-2-thiazolamine
4-methyl-N-(3-methylbutyl)-5-(5-methyl-3-phenyl-4H-isoxazol-5-yl)-2-thiazolecarboxamide4-methyl-N-(3-methylbutyl)-5-(5-methyl-3-phenyl-4H-isoxazol-5-yl)-2-thiazolecarboxamide
4-methylthiazole-5-carboxylic acid4-Methyl-thiazole-5-carboxylic acid
4,5-dichloro-3-isothiazolecarboxylic acid [1-(2-furanylmethylamino)-1-oxopropan-2-yl] ester4,5-dichloro-3-isothiazolecarboxylic acid [1-(2-furanylmethylamino)-1-oxopropan-2-yl] ester
4,5-dichloro-3-isothiazolecarboxylic acid [1-oxo-1-(thiophen-2-ylmethylamino)butan-2-yl] ester4,5-dichloro-3-isothiazolecarboxylic acid [1-oxo-1-(thiophen-2-ylmethylamino)butan-2-yl] ester
5-[1-[(4-fluorophenyl)methyl]-3-pyrazolyl]-2-phenylthiazole5-[1-[(4-fluorophenyl)methyl]-3-pyrazolyl]-2-phenylthiazole
5-[1-[(4-methylphenyl)methyl]-3-pyrazolyl]-2-phenylthiazole5-[1-[(4-methylphenyl)methyl]-3-pyrazolyl]-2-phenylthiazole
5-[2-(4-chlorophenyl)-4-methyl-5-thiazolyl]-3-(3-fluorophenyl)-5-methyl-4H-isoxazole5-[2-(4-chlorophenyl)-4-methyl-5-thiazolyl]-3-(3-fluorophenyl)-5-methyl-4H-isoxazole
5-ethyl-N-[[2-(3-pyridinyl)-4-thiazolyl]methyl]-2-thiophenesulfonamide5-ethyl-N-[[2-(3-pyridinyl)-4-thiazolyl]methyl]-2-thiophenesulfonamide
5-ethyl-N-[2-(2-phenyl-4-thiazolyl)ethyl]-2-thiophenesulfonamide5-ethyl-N-[2-(2-phenyl-4-thiazolyl)ethyl]-2-thiophenesulfonamide
5-methyl-2-(2-phenylethylamino)-4-thiazolecarboxylic acid ethyl ester5-methyl-2-(2-phenylethylamino)-4-thiazolecarboxylic acid ethyl ester
amiphenazoleamiphenazole
amthamine5-(2-aminoethyl)-4-methyl-2-thiazolamine
chlormethiazole5-(2-chloroethyl)-4-methylthiazole
curacin aCuracin A
fatostatin4-(4-methylphenyl)-2-(2-propyl-4-pyridinyl)thiazole
fentiazac2-[4-(4-chlorophenyl)-2-phenyl-5-thiazolyl]acetic acid
fr 122047[4,5-bis(4-methoxyphenyl)-2-thiazolyl]-(4-methyl-1-piperazinyl)methanone
mycothiazolemycothiazole
N-(4,5-dihydrothiazol-2-yl)-3,5-dimethyl-1-adamantanecarboxamideN-(4,5-dihydrothiazol-2-yl)-3,5-dimethyl-1-adamantanecarboxamide
N-(4,5-dimethyl-2-thiazolyl)cyclohexanecarboxamideN-(4,5-dimethyl-2-thiazolyl)cyclohexanecarboxamide
N-(4,5-dithiophen-2-yl-2-thiazolyl)-2-methyl-1-cyclopropanecarboxamideN-(4,5-dithiophen-2-yl-2-thiazolyl)-2-methyl-1-cyclopropanecarboxamide
N-(5-acetyl-4-methyl-2-thiazolyl)-2-(2,4-dichlorophenoxy)acetamideN-(5-acetyl-4-methyl-2-thiazolyl)-2-(2,4-dichlorophenoxy)acetamide
N-(5-acetyl-4-methyl-2-thiazolyl)-2-methylpropanamideN-(5-acetyl-4-methyl-2-thiazolyl)-2-methylpropanamide
N-(5-acetyl-4-methyl-2-thiazolyl)-5-bromo-2-furancarboxamideN-(5-acetyl-4-methyl-2-thiazolyl)-5-bromo-2-furancarboxamide
N-(5-ethyl-4-phenyl-2-thiazolyl)-2-methoxyacetamideN-(5-ethyl-4-phenyl-2-thiazolyl)-2-methoxyacetamide
N-[(4-methoxyphenyl)methyl]-2-(phenylmethyl)-4-thiazolecarboxamideN-[(4-methoxyphenyl)methyl]-2-(phenylmethyl)-4-thiazolecarboxamide
N-[4-methyl-5-[2-(4-methylanilino)-4-thiazolyl]-2-thiazolyl]-2-furancarboxamideN-[4-methyl-5-[2-(4-methylanilino)-4-thiazolyl]-2-thiazolyl]-2-furancarboxamide
N-[5-[2-(2,4-dichloroanilino)-4-thiazolyl]-4-methyl-2-thiazolyl]-4-pentenamideN-[5-[2-(2,4-dichloroanilino)-4-thiazolyl]-4-methyl-2-thiazolyl]-4-pentenamide
N-[5-[2-(4-chloroanilino)-4-thiazolyl]-4-methyl-2-thiazolyl]-2-furancarboxamideN-[5-[2-(4-chloroanilino)-4-thiazolyl]-4-methyl-2-thiazolyl]-2-furancarboxamide
N-[5-[2-(5-chloro-2-methylanilino)-4-thiazolyl]-4-methyl-2-thiazolyl]heptanamideN-[5-[2-(5-chloro-2-methylanilino)-4-thiazolyl]-4-methyl-2-thiazolyl]heptanamide
N,N,4-trimethyl-2-[[(5-methyl-2-furanyl)-oxomethyl]amino]-5-thiazolecarboxamideN,N,4-trimethyl-2-[[(5-methyl-2-furanyl)-oxomethyl]amino]-5-thiazolecarboxamide
N1-(4-methyl-1,3-thiazol-2-yl)acetamideN1-(4-methyl-1,3-thiazol-2-yl)acetamide
tiotidine1-cyano-3-[2-[[2-(diaminomethylideneamino)-4-thiazolyl]methylthio]ethyl]-2-methylguanidine

Research

Studies (1,129)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990653 (57.84)18.7374
1990's169 (14.97)18.2507
2000's155 (13.73)29.6817
2010's119 (10.54)24.3611
2020's33 (2.92)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials103 (6.71%)5.53%
Reviews63 (4.10%)6.00%
Case Studies78 (5.08%)4.05%
Observational1 (0.07%)0.25%
Other1,291 (84.05%)84.16%